locus-tag	class	description
CBP35_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBP35_RS00010	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CBP35_RS00015	COG0594	ribonuclease P activity
CBP35_RS00020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CBP35_RS00025	COG0706	membrane insertase activity
CBP35_RS00035	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CBP35_RS00070	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CBP35_RS00085	COG0724	RNA recognition motif
CBP35_RS00090	COG0724	RNA recognition motif
CBP35_RS00095	COG2119	membrane
CBP35_RS00100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBP35_RS00105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBP35_RS00110	COG0840	transmembrane signaling receptor activity
CBP35_RS00120	COG2267	carboxylic ester hydrolase activity
CBP35_RS00125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBP35_RS00145	COG2814	Major facilitator Superfamily
CBP35_RS00150	COG0826	peptidase U32
CBP35_RS00155	COG0826	peptidase U32
CBP35_RS00160	COG3154	lipid carrier protein
CBP35_RS00170	COG0163	prenyltransferase activity
CBP35_RS00175	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CBP35_RS00185	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CBP35_RS00195	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CBP35_RS00200	COG0861	Integral membrane protein TerC family
CBP35_RS00205	COG0631	protein serine/threonine phosphatase activity
CBP35_RS00215	COG1234	tRNA 3'-trailer cleavage
CBP35_RS00220	COG4969	Belongs to the N-Me-Phe pilin family
CBP35_RS00225	COG3307	-O-antigen
CBP35_RS00230	COG0315	cyclic pyranopterin monophosphate synthase activity
CBP35_RS00235	COG4783	chaperone-mediated protein folding
CBP35_RS00240	COG1950	PFAM Membrane protein of
CBP35_RS00250	COG0861	Integral membrane protein TerC family
CBP35_RS00275	COG0625	glutathione transferase activity
CBP35_RS00305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBP35_RS00330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CBP35_RS00350	COG4566	intracellular signal transduction
CBP35_RS00370	COG1522	sequence-specific DNA binding
CBP35_RS00380	COG1862	Preprotein translocase
CBP35_RS00385	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBP35_RS00390	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CBP35_RS00400	COG0758	DNA mediated transformation
CBP35_RS00410	COG0242	peptide deformylase activity
CBP35_RS00435	COG0126	phosphoglycerate kinase activity
CBP35_RS00440	COG0284	orotidine-5'-phosphate decarboxylase activity
CBP35_RS00445	COG0697	spore germination
CBP35_RS00455	COG0840	transmembrane signaling receptor activity
CBP35_RS00465	COG2814	Major facilitator Superfamily
CBP35_RS00485	COG0270	DNA (cytosine-5-)-methyltransferase activity
CBP35_RS00490	COG0482	sulfurtransferase activity
CBP35_RS00505	COG3976	FMN-binding domain protein
CBP35_RS00505	COG1053	succinate dehydrogenase
CBP35_RS00525	COG1012	belongs to the aldehyde dehydrogenase family
CBP35_RS00530	COG2084	Dehydrogenase
CBP35_RS00545	COG0307	riboflavin synthase, alpha
CBP35_RS00560	COG0737	Belongs to the 5'-nucleotidase family
CBP35_RS00570	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CBP35_RS00585	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CBP35_RS00610	COG4786	Flagellar basal body rod
CBP35_RS00620	COG3258	Cytochrome c
CBP35_RS00625	COG4566	intracellular signal transduction
CBP35_RS00640	COG0280	phosphate acetyltransferase
CBP35_RS00640	COG0281	malic enzyme
CBP35_RS00655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CBP35_RS00660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBP35_RS00665	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CBP35_RS00680	COG2329	Antibiotic biosynthesis monooxygenase
CBP35_RS00695	COG2137	regulation of response to DNA damage stimulus
CBP35_RS00700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CBP35_RS00730	COG0642	Histidine kinase
CBP35_RS00755	COG2365	Tyrosine phosphatase family
CBP35_RS00760	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS00765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBP35_RS00790	COG3148	PFAM DTW domain containing protein
CBP35_RS00825	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CBP35_RS00835	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CBP35_RS00840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CBP35_RS00845	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CBP35_RS00850	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CBP35_RS00860	COG0006	proline dipeptidase activity
CBP35_RS00890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CBP35_RS00895	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CBP35_RS00900	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS00905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBP35_RS00910	COG0598	Magnesium transport protein CorA
CBP35_RS00925	COG1214	PFAM Peptidase M22, glycoprotease
CBP35_RS00935	COG4095	Psort location CytoplasmicMembrane, score
CBP35_RS00955	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CBP35_RS00965	COG3118	belongs to the thioredoxin family
CBP35_RS00970	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CBP35_RS00980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CBP35_RS00995	COG0735	belongs to the Fur family
CBP35_RS01000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBP35_RS01005	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CBP35_RS01020	COG0495	leucyl-tRNA aminoacylation
CBP35_RS01030	COG0010	Belongs to the arginase family
CBP35_RS01035	COG1414	Transcriptional regulator
CBP35_RS01045	COG1063	alcohol dehydrogenase
CBP35_RS01075	COG3360	Dodecin
CBP35_RS01080	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CBP35_RS01105	COG3135	benzoate transporter
CBP35_RS01110	COG0189	ligase activity
CBP35_RS01140	COG0121	glutamine amidotransferase
CBP35_RS01150	COG1942	4-Oxalocrotonate Tautomerase
CBP35_RS01160	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CBP35_RS01185	COG0018	arginyl-trna synthetase
CBP35_RS01190	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CBP35_RS01205	COG1137	ATPase activity
CBP35_RS01210	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CBP35_RS01235	COG0659	secondary active sulfate transmembrane transporter activity
CBP35_RS01245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CBP35_RS01250	COG0589	response to stress
CBP35_RS01255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBP35_RS01265	COG0842	Transport permease protein
CBP35_RS01270	COG0842	Transport permease protein
CBP35_RS01270	COG1129	ABC transporter
CBP35_RS01275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBP35_RS01285	COG3243	poly(R)-hydroxyalkanoic acid synthase
CBP35_RS01315	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CBP35_RS01330	COG2967	ApaG domain
CBP35_RS01335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CBP35_RS01340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CBP35_RS01365	COG0489	protein tyrosine kinase activity
CBP35_RS01375	COG3267	Type II secretory pathway component ExeA
CBP35_RS01375	COG3409	Peptidoglycan-binding domain 1 protein
CBP35_RS01400	COG0367	asparagine synthase
CBP35_RS01415	COG0438	transferase activity, transferring glycosyl groups
CBP35_RS01435	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CBP35_RS01435	COG2755	lipolytic protein G-D-S-L family
CBP35_RS01465	COG1216	Glycosyl transferase, family 2
CBP35_RS01465	COG0463	Glycosyl transferase, family 2
CBP35_RS01485	COG0546	phosphoglycolate phosphatase activity
CBP35_RS01485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CBP35_RS01490	COG2076	Multidrug Resistance protein
CBP35_RS01535	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS01550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBP35_RS01590	COG0546	phosphoglycolate phosphatase activity
CBP35_RS01610	COG0512	Glutamine amidotransferase of anthranilate synthase
CBP35_RS01620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBP35_RS01625	COG0134	indole-3-glycerol-phosphate synthase activity
CBP35_RS01630	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CBP35_RS01650	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CBP35_RS01675	COG0783	Belongs to the Dps family
CBP35_RS01685	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CBP35_RS01695	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CBP35_RS01705	COG3842	ATPase activity
CBP35_RS01720	COG0395	ABC-type sugar transport system, permease component
CBP35_RS01735	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CBP35_RS01740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CBP35_RS01745	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CBP35_RS01750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CBP35_RS01755	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CBP35_RS01760	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CBP35_RS01765	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CBP35_RS01770	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CBP35_RS01775	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CBP35_RS01780	COG1841	ribosomal large subunit assembly
CBP35_RS01785	COG0200	Binds to the 23S rRNA
CBP35_RS01790	COG0201	protein transport
CBP35_RS01795	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CBP35_RS01800	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CBP35_RS01805	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CBP35_RS01810	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CBP35_RS01815	COG0202	RNA polymerase activity
CBP35_RS01820	COG0203	ribosomal protein L17
CBP35_RS01850	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS01855	COG0583	DNA-binding transcription factor activity
CBP35_RS01865	COG2095	MarC family integral membrane protein
CBP35_RS01905	COG2847	Copper chaperone PCu(A)C
CBP35_RS01920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBP35_RS01930	COG2072	flavoprotein involved in K transport
CBP35_RS01935	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS01960	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS01960	COG0204	Acyl-transferase
CBP35_RS01990	COG0343	queuine tRNA-ribosyltransferase activity
CBP35_RS02015	COG0210	DNA helicase
CBP35_RS02020	COG0679	Auxin Efflux Carrier
CBP35_RS02025	COG0438	transferase activity, transferring glycosyl groups
CBP35_RS02040	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CBP35_RS02045	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CBP35_RS02050	COG2814	Major facilitator Superfamily
CBP35_RS02055	COG0583	DNA-binding transcription factor activity
CBP35_RS02060	COG0861	Integral membrane protein TerC family
CBP35_RS02075	COG1832	CoA-binding protein
CBP35_RS02105	COG0714	Associated with various cellular activities
CBP35_RS02110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBP35_RS02115	COG0084	hydrolase, TatD family'
CBP35_RS02130	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBP35_RS02160	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS02165	COG2423	ornithine cyclodeaminase activity
CBP35_RS02170	COG0697	spore germination
CBP35_RS02220	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS02235	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS02270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBP35_RS02275	COG0384	phenazine biosynthesis protein PhzF
CBP35_RS02280	COG0625	glutathione transferase activity
CBP35_RS02285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBP35_RS02290	COG0697	spore germination
CBP35_RS02300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBP35_RS02310	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CBP35_RS02315	COG1256	bacterial-type flagellum assembly
CBP35_RS02325	COG1706	bacterial-type flagellum-dependent cell motility
CBP35_RS02330	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CBP35_RS02340	COG4787	bacterial-type flagellum-dependent cell motility
CBP35_RS02345	COG1749	Flagellar hook protein flgE
CBP35_RS02350	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CBP35_RS02355	COG1558	bacterial-type flagellum-dependent cell motility
CBP35_RS02360	COG1815	bacterial-type flagellum-dependent cell motility
CBP35_RS02395	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CBP35_RS02405	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CBP35_RS02410	COG0745	RESPONSE REGULATOR receiver
CBP35_RS02415	COG1360	Flagellar Motor Protein
CBP35_RS02420	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
CBP35_RS02435	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CBP35_RS02450	COG3609	addiction module antidote protein, CC2985 family
CBP35_RS02460	COG1677	Flagellar hook-basal body complex protein FliE
CBP35_RS02495	COG1580	Controls the rotational direction of flagella during chemotaxis
CBP35_RS02505	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CBP35_RS02515	COG1338	Plays a role in the flagellum-specific transport system
CBP35_RS02520	COG1987	bacterial-type flagellum assembly
CBP35_RS02530	COG2197	response regulator
CBP35_RS02545	COG2201	protein-glutamate methylesterase activity
CBP35_RS02555	COG0835	chemotaxis
CBP35_RS02565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CBP35_RS02570	COG2201	protein-glutamate methylesterase activity
CBP35_RS02575	COG0488	(ABC) transporter
CBP35_RS02605	COG0789	Transcriptional regulator
CBP35_RS02615	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS02620	COG0288	reversible hydration of carbon dioxide
CBP35_RS02625	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CBP35_RS02630	COG0183	Belongs to the thiolase family
CBP35_RS02640	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS02650	COG3012	SEC-C Motif Domain Protein
CBP35_RS02655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CBP35_RS02675	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS02680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CBP35_RS02685	COG1024	Enoyl-CoA hydratase
CBP35_RS02700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBP35_RS02705	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS02710	COG3246	L-lysine catabolic process to acetate
CBP35_RS02715	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBP35_RS02760	COG3162	membrane
CBP35_RS02765	COG0477	Major facilitator Superfamily
CBP35_RS02780	COG0683	leucine binding
CBP35_RS02785	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CBP35_RS02805	COG0714	Associated with various cellular activities
CBP35_RS02815	COG2010	Cytochrome c
CBP35_RS02820	COG1845	cytochrome c oxidase, subunit III
CBP35_RS02850	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CBP35_RS02855	COG3177	Filamentation induced by cAMP protein fic
CBP35_RS02895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CBP35_RS02905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CBP35_RS02910	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CBP35_RS02915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CBP35_RS02930	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CBP35_RS02935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CBP35_RS02940	COG0316	Belongs to the HesB IscA family
CBP35_RS02945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CBP35_RS02950	COG0739	heme binding
CBP35_RS02955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CBP35_RS02960	COG0583	DNA-binding transcription factor activity
CBP35_RS02980	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBP35_RS02985	COG2205	protein histidine kinase activity
CBP35_RS02990	COG3706	GGDEF domain
CBP35_RS03015	COG3360	Dodecin
CBP35_RS03045	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CBP35_RS03055	COG1560	Kdo2-lipid A biosynthetic process
CBP35_RS03065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CBP35_RS03075	COG1333	cytochrome c biogenesis protein
CBP35_RS03080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBP35_RS03085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CBP35_RS03090	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CBP35_RS03105	COG1965	Belongs to the frataxin family
CBP35_RS03170	COG0069	glutamate synthase activity
CBP35_RS03170	COG0070	glutamate synthase
CBP35_RS03170	COG0067	glutamate synthase
CBP35_RS03185	COG0765	amino acid transport
CBP35_RS03190	COG1126	abc transporter atp-binding protein
CBP35_RS03195	COG1127	ABC transporter
CBP35_RS03200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBP35_RS03205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CBP35_RS03225	COG1131	(ABC) transporter
CBP35_RS03230	COG0842	Transport permease protein
CBP35_RS03235	COG5007	Belongs to the BolA IbaG family
CBP35_RS03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CBP35_RS03245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CBP35_RS03255	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBP35_RS03260	COG0131	Imidazoleglycerol-phosphate dehydratase
CBP35_RS03270	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CBP35_RS03300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CBP35_RS03305	COG0107	imidazoleglycerol-phosphate synthase activity
CBP35_RS03310	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CBP35_RS03315	COG0140	phosphoribosyl-ATP diphosphatase activity
CBP35_RS03330	COG0537	adenosine 5'-monophosphoramidase activity
CBP35_RS03335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBP35_RS03340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CBP35_RS03345	COG0805	protein transport
CBP35_RS03350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBP35_RS03355	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CBP35_RS03370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CBP35_RS03380	COG1970	mechanosensitive ion channel activity
CBP35_RS03385	COG0723	plastoquinol--plastocyanin reductase activity
CBP35_RS03390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CBP35_RS03395	COG2857	Cytochrome c1
CBP35_RS03400	COG0625	glutathione transferase activity
CBP35_RS03405	COG2969	positive regulation of protein catabolic process
CBP35_RS03420	COG0653	protein targeting
CBP35_RS03425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CBP35_RS03435	COG0494	nUDIX hydrolase
CBP35_RS03440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CBP35_RS03445	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CBP35_RS03450	COG0237	dephospho-CoA kinase activity
CBP35_RS03455	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CBP35_RS03495	COG0142	geranyltranstransferase activity
CBP35_RS03500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CBP35_RS03505	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CBP35_RS03510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CBP35_RS03520	COG0494	nUDIX hydrolase
CBP35_RS03525	COG0442	prolyl-tRNA aminoacylation
CBP35_RS03530	COG0741	lytic transglycosylase activity
CBP35_RS03545	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CBP35_RS03555	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CBP35_RS03565	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CBP35_RS03575	COG0583	DNA-binding transcription factor activity
CBP35_RS03590	COG0584	glycerophosphoryl diester phosphodiesterase
CBP35_RS03595	COG3842	ATPase activity
CBP35_RS03600	COG0395	ABC-type sugar transport system, permease component
CBP35_RS03605	COG1175	transmembrane transport
CBP35_RS03615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CBP35_RS03635	COG2226	methyltransferase
CBP35_RS03650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBP35_RS03670	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CBP35_RS03675	COG1715	Restriction endonuclease
CBP35_RS03690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBP35_RS03695	COG0302	gtp cyclohydrolase
CBP35_RS03720	COG0588	phosphoglycerate mutase activity
CBP35_RS03740	COG4608	Belongs to the ABC transporter superfamily
CBP35_RS03745	COG0444	Belongs to the ABC transporter superfamily
CBP35_RS03750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBP35_RS03760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CBP35_RS03765	COG0193	aminoacyl-tRNA hydrolase activity
CBP35_RS03770	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CBP35_RS03775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CBP35_RS03785	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CBP35_RS03790	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CBP35_RS03800	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CBP35_RS03815	COG1660	Displays ATPase and GTPase activities
CBP35_RS03820	COG0497	DNA recombination
CBP35_RS03830	COG1420	regulation of RNA biosynthetic process
CBP35_RS03850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CBP35_RS03855	COG1758	RNA polymerase activity
CBP35_RS03860	COG0194	GDP metabolic process
CBP35_RS03865	COG1561	YicC-like family, N-terminal region
CBP35_RS03885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CBP35_RS03890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CBP35_RS03940	COG0798	PFAM Bile acid sodium symporter
CBP35_RS03965	COG0737	Belongs to the 5'-nucleotidase family
CBP35_RS03970	COG1193	negative regulation of DNA recombination
CBP35_RS03975	COG2003	Belongs to the UPF0758 family
CBP35_RS03980	COG1047	Peptidyl-prolyl cis-trans
CBP35_RS03985	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CBP35_RS03990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CBP35_RS03990	COG0617	tRNA 3'-terminal CCA addition
CBP35_RS03990	COG0517	IMP dehydrogenase activity
CBP35_RS03995	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBP35_RS04000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CBP35_RS04020	COG0574	Belongs to the PEP-utilizing enzyme family
CBP35_RS04020	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBP35_RS04045	COG1994	Peptidase M50
CBP35_RS04050	COG0009	L-threonylcarbamoyladenylate synthase
CBP35_RS04055	COG0613	PHP domain protein
CBP35_RS04065	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBP35_RS04075	COG4591	ABC-type transport system involved in lipoprotein release permease component
CBP35_RS04080	COG1136	(ABC) transporter
CBP35_RS04085	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CBP35_RS04095	COG0196	riboflavin kinase activity
CBP35_RS04105	COG3781	membrane
CBP35_RS04110	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS04115	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS04120	COG3132	Protein of unknown function, DUF480
CBP35_RS04125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CBP35_RS04130	COG2826	transposase and inactivated derivatives, IS30 family
CBP35_RS04140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBP35_RS04140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBP35_RS04150	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CBP35_RS04155	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CBP35_RS04160	COG0492	ferredoxin-NADP+ reductase activity
CBP35_RS04165	COG1674	ftsk spoiiie
CBP35_RS04170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CBP35_RS04175	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CBP35_RS04180	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBP35_RS04205	COG1392	Phosphate transport regulator
CBP35_RS04210	COG0306	phosphate transporter
CBP35_RS04225	COG0228	four-way junction DNA binding
CBP35_RS04230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CBP35_RS04240	COG0335	large ribosomal subunit rRNA binding
CBP35_RS04245	COG0494	nUDIX hydrolase
CBP35_RS04250	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CBP35_RS04255	COG1162	GTPase activity
CBP35_RS04260	COG2154	pterin-4-alpha-carbinolamine dehydratase
CBP35_RS04265	COG0501	Belongs to the peptidase M48B family
CBP35_RS04270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CBP35_RS04275	COG0513	Belongs to the DEAD box helicase family
CBP35_RS04290	COG2814	Major facilitator Superfamily
CBP35_RS04300	COG2084	Dehydrogenase
CBP35_RS04305	COG0516	GMP reductase activity
CBP35_RS04315	COG0210	DNA helicase
CBP35_RS04340	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CBP35_RS04375	COG0625	glutathione transferase activity
CBP35_RS04385	COG0655	NAD(P)H dehydrogenase (quinone) activity
CBP35_RS04395	COG0412	Dienelactone hydrolase
CBP35_RS04410	COG3275	phosphorelay sensor kinase activity
CBP35_RS04415	COG0165	Argininosuccinate lyase
CBP35_RS04420	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS04450	COG5001	Diguanylate cyclase
CBP35_RS04450	COG3447	MASE1 domain protein
CBP35_RS04450	COG5002	protein histidine kinase activity
CBP35_RS04455	COG1304	FMN binding
CBP35_RS04470	COG0840	transmembrane signaling receptor activity
CBP35_RS04475	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBP35_RS04475	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CBP35_RS04485	COG3022	response to hydroperoxide
CBP35_RS04515	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CBP35_RS04520	COG0424	maF-like protein
CBP35_RS04525	COG1399	metal-binding, possibly nucleic acid-binding protein
CBP35_RS04530	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CBP35_RS04535	COG0416	fatty acid biosynthetic process
CBP35_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS04555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBP35_RS04560	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CBP35_RS04580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CBP35_RS04585	COG0481	GTPase activity
CBP35_RS04590	COG0681	Belongs to the peptidase S26 family
CBP35_RS04600	COG0571	ribonuclease III activity
CBP35_RS04605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CBP35_RS04610	COG1381	Involved in DNA repair and RecF pathway recombination
CBP35_RS04615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CBP35_RS04620	COG0736	holo-[acyl-carrier-protein] synthase activity
CBP35_RS04625	COG1472	Belongs to the glycosyl hydrolase 3 family
CBP35_RS04650	COG0762	integral membrane protein
CBP35_RS04655	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CBP35_RS04660	COG0159	tryptophan synthase activity
CBP35_RS04665	COG0133	tryptophan synthase activity
CBP35_RS04670	COG0135	phosphoribosylanthranilate isomerase activity
CBP35_RS04675	COG0101	tRNA pseudouridine synthase activity
CBP35_RS04695	COG0473	3-isopropylmalate dehydrogenase activity
CBP35_RS04700	COG0066	3-isopropylmalate dehydratase activity
CBP35_RS04725	COG0484	heat shock protein binding
CBP35_RS04730	COG0443	Heat shock 70 kDa protein
CBP35_RS04735	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CBP35_RS04740	COG0360	Binds together with S18 to 16S ribosomal RNA
CBP35_RS04750	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CBP35_RS04755	COG0359	binds to the 23S rRNA
CBP35_RS04775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CBP35_RS04785	COG0436	Aminotransferase
CBP35_RS04800	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CBP35_RS04805	COG1763	Mo-molybdopterin cofactor biosynthetic process
CBP35_RS04810	COG0303	'Molybdopterin
CBP35_RS04840	COG0314	molybdopterin synthase activity
CBP35_RS04845	COG0542	response to heat
CBP35_RS04865	COG2197	response regulator
CBP35_RS04890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBP35_RS04900	COG0004	ammonium transporteR
CBP35_RS04905	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CBP35_RS04915	COG4968	Prepilin-type N-terminal cleavage methylation domain
CBP35_RS04950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBP35_RS04950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CBP35_RS04960	COG0436	Aminotransferase
CBP35_RS04965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CBP35_RS04970	COG1185	polyribonucleotide nucleotidyltransferase activity
CBP35_RS04975	COG0604	alcohol dehydrogenase
CBP35_RS04975	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS04975	COG3321	synthase
CBP35_RS04980	COG0149	triose-phosphate isomerase activity
CBP35_RS04995	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBP35_RS05000	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBP35_RS05005	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBP35_RS05010	COG0649	NAD binding
CBP35_RS05025	COG1034	ATP synthesis coupled electron transport
CBP35_RS05030	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CBP35_RS05035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CBP35_RS05045	COG0713	ATP synthesis coupled electron transport
CBP35_RS05060	COG1007	ATP synthesis coupled electron transport
CBP35_RS05075	COG1132	(ABC) transporter
CBP35_RS05095	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBP35_RS05115	COG0071	Belongs to the small heat shock protein (HSP20) family
CBP35_RS05120	COG4181	ATPase activity
CBP35_RS05125	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CBP35_RS05140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBP35_RS05175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CBP35_RS05215	COG0745	RESPONSE REGULATOR receiver
CBP35_RS05225	COG0586	Pfam SNARE associated Golgi protein
CBP35_RS05240	COG0860	N-Acetylmuramoyl-L-alanine amidase
CBP35_RS05245	COG0802	atpase or kinase
CBP35_RS05250	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CBP35_RS05265	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS05270	COG4974	Belongs to the 'phage' integrase family
CBP35_RS05280	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CBP35_RS05290	COG2833	Protein of unknown function (DUF455)
CBP35_RS05310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CBP35_RS05320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CBP35_RS05325	COG0504	CTP synthase activity
CBP35_RS05330	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CBP35_RS05335	COG0756	dUTP diphosphatase activity
CBP35_RS05345	COG1047	Peptidyl-prolyl cis-trans
CBP35_RS05350	COG2850	peptidyl-arginine hydroxylation
CBP35_RS05365	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
CBP35_RS05370	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CBP35_RS05375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBP35_RS05380	COG0500	methyltransferase
CBP35_RS05395	COG0741	lytic transglycosylase activity
CBP35_RS05405	COG0840	transmembrane signaling receptor activity
CBP35_RS05435	COG4628	conserved protein (DUF2132)
CBP35_RS05455	COG3634	alkyl hydroperoxide reductase activity
CBP35_RS05465	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CBP35_RS05480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CBP35_RS05505	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBP35_RS05510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS05530	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS05545	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CBP35_RS05550	COG0405	Gamma-glutamyltransferase
CBP35_RS05555	COG3540	Alkaline phosphatase
CBP35_RS05575	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBP35_RS05590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CBP35_RS05595	COG1187	pseudouridine synthase activity
CBP35_RS05600	COG0105	UTP biosynthetic process
CBP35_RS05605	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CBP35_RS05620	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CBP35_RS05625	COG0124	histidyl-tRNA synthetase
CBP35_RS05635	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CBP35_RS05640	COG1160	GTP binding
CBP35_RS05645	COG1923	regulation of RNA biosynthetic process
CBP35_RS05650	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CBP35_RS05655	COG0330	HflC and HflK could
CBP35_RS05660	COG0330	HflC and HflK could
CBP35_RS05665	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CBP35_RS05670	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CBP35_RS05675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CBP35_RS05740	COG0174	glutamine synthetase
CBP35_RS05750	COG3852	Histidine kinase
CBP35_RS05755	COG2204	response regulator
CBP35_RS05765	COG0708	Exodeoxyribonuclease III
CBP35_RS05780	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CBP35_RS05785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBP35_RS05790	COG0277	FAD linked oxidase domain protein
CBP35_RS05800	COG1295	ribonuclease BN
CBP35_RS05805	COG0277	FAD linked oxidase domain protein
CBP35_RS05820	COG0517	IMP dehydrogenase activity
CBP35_RS05825	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CBP35_RS05835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CBP35_RS05840	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CBP35_RS05845	COG0741	lytic transglycosylase activity
CBP35_RS05870	COG0557	exoribonuclease II activity
CBP35_RS05875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CBP35_RS05875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CBP35_RS05900	COG0052	Belongs to the universal ribosomal protein uS2 family
CBP35_RS05905	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CBP35_RS05910	COG0528	UMP kinase activity
CBP35_RS05915	COG0233	cytoplasmic translational termination
CBP35_RS05920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CBP35_RS05930	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CBP35_RS05935	COG0750	zinc metalloprotease
CBP35_RS05950	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBP35_RS05955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBP35_RS05960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBP35_RS05970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBP35_RS05975	COG0505	Belongs to the CarA family
CBP35_RS05980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CBP35_RS05985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBP35_RS06010	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CBP35_RS06015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBP35_RS06025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CBP35_RS06070	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CBP35_RS06075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CBP35_RS06080	COG0573	inorganic phosphate transmembrane transporter activity
CBP35_RS06085	COG0581	inorganic phosphate transmembrane transporter activity
CBP35_RS06090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CBP35_RS06095	COG0704	Plays a role in the regulation of phosphate uptake
CBP35_RS06110	COG0534	Mate efflux family protein
CBP35_RS06120	COG0254	rRNA binding
CBP35_RS06150	COG3108	Peptidase M15
CBP35_RS06180	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CBP35_RS06185	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CBP35_RS06205	COG0741	lytic transglycosylase activity
CBP35_RS06205	COG1388	LysM domain
CBP35_RS06210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBP35_RS06245	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBP35_RS06260	COG0746	molybdenum cofactor guanylyltransferase activity
CBP35_RS06265	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CBP35_RS06300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CBP35_RS06305	COG0840	transmembrane signaling receptor activity
CBP35_RS06310	COG0835	chemotaxis
CBP35_RS06325	COG0347	Belongs to the P(II) protein family
CBP35_RS06335	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CBP35_RS06355	COG1595	DNA-templated transcription, initiation
CBP35_RS06360	COG0028	Belongs to the TPP enzyme family
CBP35_RS06365	COG0440	acetolactate synthase activity
CBP35_RS06370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CBP35_RS06375	COG1183	phosphatidylcholine synthase activity
CBP35_RS06380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBP35_RS06395	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CBP35_RS06400	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CBP35_RS06415	COG2832	Protein of unknown function (DUF454)
CBP35_RS06420	COG0242	peptide deformylase activity
CBP35_RS06425	COG0582	viral genome integration into host DNA
CBP35_RS06430	COG3657	addiction module killer protein
CBP35_RS06445	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS06460	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CBP35_RS06465	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS06575	COG0582	viral genome integration into host DNA
CBP35_RS06580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CBP35_RS06585	COG0308	aminopeptidase N
CBP35_RS06595	COG2267	carboxylic ester hydrolase activity
CBP35_RS06600	COG0667	Aldo Keto reductase
CBP35_RS06605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CBP35_RS06610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CBP35_RS06620	COG3577	Aspartyl protease
CBP35_RS06625	COG1666	GTP binding
CBP35_RS06630	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CBP35_RS06635	COG0137	argininosuccinate synthase activity
CBP35_RS06640	COG3123	guanosine phosphorylase activity
CBP35_RS06650	COG1393	Belongs to the ArsC family
CBP35_RS06675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBP35_RS06715	COG1840	ABC-type Fe3 transport system, periplasmic component
CBP35_RS06785	COG0582	viral genome integration into host DNA
CBP35_RS06795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CBP35_RS06795	COG4651	solute:proton antiporter activity
CBP35_RS06810	COG0488	(ABC) transporter
CBP35_RS06825	COG3191	aminopeptidase activity
CBP35_RS06845	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CBP35_RS06960	COG0582	viral genome integration into host DNA
CBP35_RS06990	COG1793	dna ligase
CBP35_RS07000	COG4166	transmembrane transport
CBP35_RS07005	COG4174	ABC transporter (Permease)
CBP35_RS07010	COG4239	(ABC) transporter, permease
CBP35_RS07100	COG0500	methyltransferase
CBP35_RS07110	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
CBP35_RS07145	COG0779	Required for maturation of 30S ribosomal subunits
CBP35_RS07150	COG0195	Participates in both transcription termination and antitermination
CBP35_RS07155	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CBP35_RS07160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CBP35_RS07165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CBP35_RS07180	COG1024	Enoyl-CoA hydratase
CBP35_RS07200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CBP35_RS07205	COG2867	negative regulation of translational initiation
CBP35_RS07210	COG2914	Belongs to the UPF0125 (RnfH) family
CBP35_RS07225	COG0519	Catalyzes the synthesis of GMP from XMP
CBP35_RS07225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CBP35_RS07270	COG0688	phosphatidylethanolamine metabolic process
CBP35_RS07280	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CBP35_RS07295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBP35_RS07305	COG2917	probably involved in intracellular septation
CBP35_RS07310	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBP35_RS07315	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CBP35_RS07320	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS07330	COG0559	Belongs to the binding-protein-dependent transport system permease family
CBP35_RS07340	COG0411	ABC transporter
CBP35_RS07350	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBP35_RS07350	COG1024	Enoyl-CoA hydratase
CBP35_RS07355	COG0183	Belongs to the thiolase family
CBP35_RS07360	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS07380	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS07390	COG2130	NADP-dependent
CBP35_RS07395	COG2153	protein acetylation
CBP35_RS07425	COG2183	response to ionizing radiation
CBP35_RS07445	COG0657	acetylesterase activity
CBP35_RS07460	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CBP35_RS07465	COG0826	peptidase U32
CBP35_RS07490	COG1619	proteins homologs of microcin C7 resistance protein MccF
CBP35_RS07530	COG1024	Enoyl-CoA hydratase
CBP35_RS07535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBP35_RS07550	COG2022	thiamine diphosphate biosynthetic process
CBP35_RS07565	COG0351	phosphomethylpyrimidine kinase
CBP35_RS07575	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBP35_RS07585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CBP35_RS07590	COG2895	sulfate adenylyltransferase (ATP) activity
CBP35_RS07595	COG0175	sulfate reduction
CBP35_RS07600	COG0175	sulfate reduction
CBP35_RS07615	COG0730	response to heat
CBP35_RS07625	COG2860	membrane
CBP35_RS07630	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CBP35_RS07635	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBP35_RS07640	COG0431	NADPH-dependent FMN reductase
CBP35_RS07645	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBP35_RS07650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBP35_RS07660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBP35_RS07665	COG1116	anion transmembrane transporter activity
CBP35_RS07675	COG0583	DNA-binding transcription factor activity
CBP35_RS07695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBP35_RS07740	COG0463	Glycosyl transferase, family 2
CBP35_RS07745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CBP35_RS07755	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CBP35_RS07760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CBP35_RS07790	COG0506	proline dehydrogenase activity
CBP35_RS07790	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBP35_RS07790	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CBP35_RS07805	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CBP35_RS07815	COG0670	Belongs to the BI1 family
CBP35_RS07820	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CBP35_RS07855	COG3128	pkhd-type hydroxylase
CBP35_RS07860	COG4774	siderophore transport
CBP35_RS07870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CBP35_RS07885	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CBP35_RS07890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CBP35_RS07895	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CBP35_RS07900	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CBP35_RS07905	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CBP35_RS07910	COG0072	phenylalanine-tRNA ligase activity
CBP35_RS07910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBP35_RS07915	COG0776	regulation of translation
CBP35_RS07920	COG0789	Transcriptional regulator
CBP35_RS07940	COG0024	Methionine aminopeptidase
CBP35_RS07945	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CBP35_RS07945	COG0047	phosphoribosylformylglycinamidine synthase activity
CBP35_RS07955	COG2354	Protein conserved in bacteria
CBP35_RS07960	COG3047	cAMP biosynthetic process
CBP35_RS07965	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CBP35_RS07970	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CBP35_RS07985	COG0354	folic acid binding
CBP35_RS07990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CBP35_RS07995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CBP35_RS08000	COG0470	DNA polymerase III
CBP35_RS08010	COG0084	hydrolase, TatD family'
CBP35_RS08020	COG1132	(ABC) transporter
CBP35_RS08040	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CBP35_RS08055	COG2814	Major facilitator Superfamily
CBP35_RS08065	COG2011	ABC-type metal ion transport system permease component
CBP35_RS08100	COG0697	spore germination
CBP35_RS08125	COG0583	DNA-binding transcription factor activity
CBP35_RS08135	COG0450	alkyl hydroperoxide reductase
CBP35_RS08145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CBP35_RS08155	COG4208	sulfate ABC transporter
CBP35_RS08160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CBP35_RS08165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CBP35_RS08175	COG1902	pentaerythritol trinitrate reductase activity
CBP35_RS08190	COG1054	Belongs to the UPF0176 family
CBP35_RS08195	COG2367	Beta-lactamase
CBP35_RS08200	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CBP35_RS08200	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CBP35_RS08205	COG1643	Atp-dependent helicase
CBP35_RS08210	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CBP35_RS08235	COG0732	type I restriction modification DNA specificity domain
CBP35_RS08275	COG0183	Belongs to the thiolase family
CBP35_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS08300	COG0545	Peptidyl-prolyl cis-trans isomerase
CBP35_RS08315	COG0509	glycine decarboxylation via glycine cleavage system
CBP35_RS08320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CBP35_RS08325	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBP35_RS08325	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBP35_RS08335	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBP35_RS08350	COG4120	Belongs to the binding-protein-dependent transport system permease family
CBP35_RS08365	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS08370	COG0697	spore germination
CBP35_RS08390	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CBP35_RS08430	COG2982	Protein involved in outer membrane biogenesis
CBP35_RS08435	COG0564	pseudouridine synthase activity
CBP35_RS08470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CBP35_RS08475	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CBP35_RS08490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBP35_RS08505	COG1741	Belongs to the pirin family
CBP35_RS08525	COG1741	Belongs to the pirin family
CBP35_RS08530	COG1054	Belongs to the UPF0176 family
CBP35_RS08575	COG4181	ATPase activity
CBP35_RS08580	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CBP35_RS08585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CBP35_RS08615	COG5507	3-demethylubiquinone-9 3-methyltransferase
CBP35_RS08625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CBP35_RS08645	COG0179	Fumarylacetoacetate (FAA) hydrolase
CBP35_RS08685	COG2807	transmembrane transport
CBP35_RS08700	COG3550	peptidyl-serine autophosphorylation
CBP35_RS08725	COG1739	Uncharacterized protein family UPF0029
CBP35_RS08750	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS08770	COG1414	Transcriptional regulator
CBP35_RS08795	COG0556	nucleotide-excision repair
CBP35_RS08800	COG1959	2 iron, 2 sulfur cluster binding
CBP35_RS08805	COG1104	cysteine desulfurase activity
CBP35_RS08810	COG0822	iron-sulfur transferase activity
CBP35_RS08815	COG0316	Belongs to the HesB IscA family
CBP35_RS08820	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CBP35_RS08825	COG0443	Heat shock 70 kDa protein
CBP35_RS08955	COG0024	Methionine aminopeptidase
CBP35_RS08965	COG0702	epimerase
CBP35_RS08970	COG1733	regulation of RNA biosynthetic process
CBP35_RS09010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBP35_RS09015	COG0322	excinuclease ABC activity
CBP35_RS09055	COG0579	oxidoreductase
CBP35_RS09075	COG0167	dihydroorotate dehydrogenase activity
CBP35_RS09080	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CBP35_RS09100	COG4566	intracellular signal transduction
CBP35_RS09115	COG0508	dehydrogenase complex catalyzes the overall conversion of
CBP35_RS09130	COG3318	Belongs to the UPF0149 family
CBP35_RS09130	COG3012	SEC-C Motif Domain Protein
CBP35_RS09175	COG0791	NLP P60 protein
CBP35_RS09180	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CBP35_RS09235	COG1538	Outer membrane efflux protein
CBP35_RS09245	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CBP35_RS09260	COG1309	transcriptional regulator
CBP35_RS09265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CBP35_RS09305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS09335	COG4251	negative regulation of phosphorylation
CBP35_RS09335	COG2203	Gaf domain
CBP35_RS09335	COG3706	GGDEF domain
CBP35_RS09335	COG5001	Diguanylate cyclase
CBP35_RS09350	COG0259	pyridoxamine-phosphate oxidase activity
CBP35_RS09365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CBP35_RS09370	COG2032	superoxide dismutase activity
CBP35_RS09375	COG0589	response to stress
CBP35_RS09395	COG0346	lactoylglutathione lyase activity
CBP35_RS09410	COG0534	Mate efflux family protein
CBP35_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS09450	COG0640	Transcriptional regulator
CBP35_RS09465	COG0446	pyridine nucleotide-disulphide oxidoreductase
CBP35_RS09520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CBP35_RS09525	COG1703	isobutyryl-CoA mutase activity
CBP35_RS09530	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CBP35_RS09530	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CBP35_RS09535	COG1802	Transcriptional regulator
CBP35_RS09550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CBP35_RS09570	COG2878	Part of a membrane complex involved in electron transport
CBP35_RS09580	COG0436	Aminotransferase
CBP35_RS09585	COG2171	N-acyltransferase activity
CBP35_RS09595	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBP35_RS09610	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS09620	COG0840	transmembrane signaling receptor activity
CBP35_RS09625	COG0183	Belongs to the thiolase family
CBP35_RS09700	COG1752	Esterase of the alpha-beta hydrolase superfamily
CBP35_RS09705	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CBP35_RS09715	COG1196	nuclear chromosome segregation
CBP35_RS09760	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS09775	COG0583	DNA-binding transcription factor activity
CBP35_RS09780	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS09785	COG1473	amidohydrolase
CBP35_RS09820	COG1570	exodeoxyribonuclease VII activity
CBP35_RS09825	COG0811	peptide transport
CBP35_RS09835	COG1663	tetraacyldisaccharide 4'-kinase activity
CBP35_RS09840	COG2835	tetraacyldisaccharide 4'-kinase activity
CBP35_RS09845	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CBP35_RS09850	COG0563	adenylate kinase activity
CBP35_RS09855	COG0252	asparaginase activity
CBP35_RS09860	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBP35_RS09865	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBP35_RS09895	COG0795	lipopolysaccharide-transporting ATPase activity
CBP35_RS09905	COG0583	DNA-binding transcription factor activity
CBP35_RS09940	COG1530	ribonuclease E activity
CBP35_RS09945	COG0424	maF-like protein
CBP35_RS09950	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CBP35_RS09955	COG0799	negative regulation of ribosome biogenesis
CBP35_RS09960	COG0408	coproporphyrinogen oxidase activity
CBP35_RS09965	COG0151	Belongs to the GarS family
CBP35_RS09970	COG0217	transcriptional regulatory protein
CBP35_RS09990	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CBP35_RS10005	COG4771	TonB-dependent receptor
CBP35_RS10010	COG0402	S-adenosylhomocysteine deaminase activity
CBP35_RS10015	COG3706	GGDEF domain
CBP35_RS10035	COG0484	heat shock protein binding
CBP35_RS10040	COG0217	transcriptional regulatory protein
CBP35_RS10045	COG0700	Nucleoside recognition
CBP35_RS10055	COG2925	Exonuclease
CBP35_RS10065	COG0542	response to heat
CBP35_RS10070	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CBP35_RS10095	COG0631	protein serine/threonine phosphatase activity
CBP35_RS10105	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CBP35_RS10110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CBP35_RS10120	COG0567	Dehydrogenase, E1 component
CBP35_RS10140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBP35_RS10175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CBP35_RS10190	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CBP35_RS10195	COG1605	Chorismate mutase
CBP35_RS10195	COG0077	Prephenate dehydratase
CBP35_RS10200	COG0287	Prephenate dehydrogenase
CBP35_RS10215	COG0776	regulation of translation
CBP35_RS10235	COG1006	Multisubunit Na H antiporter MnhC subunit
CBP35_RS10245	COG1863	multisubunit Na H antiporter MnhE subunit
CBP35_RS10250	COG2212	antiporter activity
CBP35_RS10265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CBP35_RS10285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBP35_RS10295	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CBP35_RS10305	COG0123	including yeast histone deacetylase and acetoin utilization protein
CBP35_RS10325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBP35_RS10335	COG0776	regulation of translation
CBP35_RS10340	COG0473	3-isopropylmalate dehydrogenase activity
CBP35_RS10350	COG0322	excinuclease ABC activity
CBP35_RS10355	COG0778	Nitroreductase
CBP35_RS10375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS10380	COG0583	DNA-binding transcription factor activity
CBP35_RS10390	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CBP35_RS10395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBP35_RS10400	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CBP35_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS10445	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBP35_RS10450	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CBP35_RS10450	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CBP35_RS10455	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CBP35_RS10470	COG0560	Phosphoserine phosphatase
CBP35_RS10475	COG1959	2 iron, 2 sulfur cluster binding
CBP35_RS10505	COG0583	DNA-binding transcription factor activity
CBP35_RS10510	COG3530	Putative quorum-sensing-regulated virulence factor
CBP35_RS10515	COG0023	Translation Initiation Factor
CBP35_RS10525	COG0513	Belongs to the DEAD box helicase family
CBP35_RS10535	COG0667	Aldo Keto reductase
CBP35_RS10545	COG2900	Belongs to the SlyX family
CBP35_RS10550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CBP35_RS10555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CBP35_RS10570	COG4829	muconolactone delta-isomerase
CBP35_RS10600	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CBP35_RS10605	COG1492	cobalamin metabolic process
CBP35_RS10610	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CBP35_RS10620	COG0778	Nitroreductase
CBP35_RS10625	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CBP35_RS10645	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CBP35_RS10650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CBP35_RS10670	COG4206	TonB-dependent receptor
CBP35_RS10685	COG0730	response to heat
CBP35_RS10710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBP35_RS10745	COG3278	Belongs to the heme-copper respiratory oxidase family
CBP35_RS10765	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS10785	COG1802	Transcriptional regulator
CBP35_RS10815	COG4654	Cytochrome c, class I
CBP35_RS10835	COG4175	Glycine betaine
CBP35_RS10840	COG4176	ABC-type proline glycine betaine transport system permease component
CBP35_RS10845	COG2113	Glycine betaine
CBP35_RS10850	COG0114	fumarate hydratase activity
CBP35_RS10865	COG1451	nucleotide metabolic process
CBP35_RS10900	COG2003	Belongs to the UPF0758 family
CBP35_RS10925	COG1475	DNA binding
CBP35_RS10995	COG1192	Involved in chromosome partitioning
CBP35_RS11085	COG0789	Transcriptional regulator
CBP35_RS11145	COG1677	Flagellar hook-basal body complex protein FliE
CBP35_RS11150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CBP35_RS11155	COG0789	Transcriptional regulator
CBP35_RS11160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CBP35_RS11170	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CBP35_RS11185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBP35_RS11190	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBP35_RS11210	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CBP35_RS11215	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CBP35_RS11225	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CBP35_RS11245	COG2326	polyphosphate kinase activity
CBP35_RS11280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBP35_RS11300	COG3174	membrane
CBP35_RS11320	COG0789	Transcriptional regulator
CBP35_RS11325	COG1742	UPF0060 membrane protein
CBP35_RS11385	COG2205	protein histidine kinase activity
CBP35_RS11390	COG0583	DNA-binding transcription factor activity
CBP35_RS11410	COG4962	Type ii secretion system protein e
CBP35_RS11415	COG3838	Conjugal transfer protein Trbc
CBP35_RS11425	COG3451	type IV secretory pathway VirB4
CBP35_RS11445	COG3504	Conjugal transfer protein
CBP35_RS11450	COG2948	multi-organism process
CBP35_RS11475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CBP35_RS11480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CBP35_RS11485	COG0740	serine-type endopeptidase activity
CBP35_RS11490	COG0544	peptidyl-prolyl cis-trans isomerase activity
CBP35_RS11515	COG1760	l-serine dehydratase
CBP35_RS11525	COG1562	ergosterol biosynthetic process
CBP35_RS11575	COG1067	ATP-dependent peptidase activity
CBP35_RS11630	COG0415	Belongs to the DNA photolyase family
CBP35_RS11685	COG2204	response regulator
CBP35_RS11710	COG0642	Histidine kinase
CBP35_RS11715	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CBP35_RS11770	COG1053	succinate dehydrogenase
CBP35_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS11790	COG1053	succinate dehydrogenase
CBP35_RS11790	COG3976	FMN-binding domain protein
CBP35_RS11865	COG0527	aspartate kinase activity
CBP35_RS11870	COG0037	tRNA processing
CBP35_RS11875	COG0825	malonyl-CoA metabolic process
CBP35_RS11885	COG0215	cysteine-tRNA ligase activity
CBP35_RS11900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CBP35_RS11905	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CBP35_RS11935	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CBP35_RS11945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CBP35_RS12010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CBP35_RS12035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CBP35_RS12055	COG0564	pseudouridine synthase activity
CBP35_RS12065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CBP35_RS12095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CBP35_RS12100	COG2918	glutathione biosynthetic process
CBP35_RS12105	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS12135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CBP35_RS12140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBP35_RS12145	COG0436	Aminotransferase
CBP35_RS12150	COG0824	Thioesterase
CBP35_RS12170	COG0826	peptidase U32
CBP35_RS12190	COG0039	L-malate dehydrogenase activity
CBP35_RS12195	COG2188	Transcriptional regulator
CBP35_RS12205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CBP35_RS12210	COG1053	succinate dehydrogenase
CBP35_RS12215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CBP35_RS12220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CBP35_RS12225	COG0372	Belongs to the citrate synthase family
CBP35_RS12235	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CBP35_RS12240	COG2194	sulfuric ester hydrolase activity
CBP35_RS12245	COG0583	DNA-binding transcription factor activity
CBP35_RS12260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CBP35_RS12275	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS12290	COG1196	nuclear chromosome segregation
CBP35_RS12290	COG3264	Mechanosensitive ion channel
CBP35_RS12295	COG1024	Enoyl-CoA hydratase
CBP35_RS12305	COG0714	Associated with various cellular activities
CBP35_RS12320	COG2951	lytic endotransglycosylase activity
CBP35_RS12325	COG1131	(ABC) transporter
CBP35_RS12330	COG0842	Transport permease protein
CBP35_RS12335	COG0683	leucine binding
CBP35_RS12350	COG0577	efflux transmembrane transporter activity
CBP35_RS12350	COG1136	(ABC) transporter
CBP35_RS12355	COG1136	(ABC) transporter
CBP35_RS12355	COG0577	efflux transmembrane transporter activity
CBP35_RS12360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBP35_RS12370	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CBP35_RS12390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBP35_RS12395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBP35_RS12405	COG0517	IMP dehydrogenase activity
CBP35_RS12420	COG0745	RESPONSE REGULATOR receiver
CBP35_RS12425	COG2205	protein histidine kinase activity
CBP35_RS12435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBP35_RS12445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CBP35_RS12455	COG0243	molybdopterin cofactor binding
CBP35_RS12460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CBP35_RS12470	COG1607	acyl-coa hydrolase
CBP35_RS12475	COG2081	HI0933 family
CBP35_RS12480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CBP35_RS12510	COG3028	Belongs to the UPF0307 family
CBP35_RS12515	COG0521	Mo-molybdopterin cofactor biosynthetic process
CBP35_RS12520	COG1063	alcohol dehydrogenase
CBP35_RS12525	COG1045	serine acetyltransferase
CBP35_RS12560	COG5001	Diguanylate cyclase
CBP35_RS12575	COG1968	undecaprenyl-diphosphatase activity
CBP35_RS12590	COG2186	Transcriptional regulator
CBP35_RS12595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CBP35_RS12610	COG3386	PFAM SMP-30 Gluconolaconase
CBP35_RS12620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBP35_RS12625	COG2721	sulfolactate sulfo-lyase activity
CBP35_RS12635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBP35_RS12650	COG1280	lysine exporter protein (LysE YggA)
CBP35_RS12665	COG1234	tRNA 3'-trailer cleavage
CBP35_RS12680	COG3608	succinylglutamate desuccinylase aspartoacylase
CBP35_RS12680	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CBP35_RS12725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CBP35_RS12740	COG1122	ATPase activity
CBP35_RS12785	COG1722	exodeoxyribonuclease VII activity
CBP35_RS12825	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CBP35_RS12830	COG0181	hydroxymethylbilane synthase activity
CBP35_RS12850	COG3038	cytochrome b561
CBP35_RS12865	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS12870	COG0525	valine-tRNA ligase activity
CBP35_RS12875	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CBP35_RS12885	COG2816	NAD+ diphosphatase activity
CBP35_RS12900	COG2948	multi-organism process
CBP35_RS12915	COG3846	protein secretion by the type IV secretion system
CBP35_RS12930	COG3451	type IV secretory pathway VirB4
CBP35_RS12945	COG4962	Type ii secretion system protein e
CBP35_RS13000	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS13030	COG4638	Rieske (2fe-2S)
CBP35_RS13060	COG3971	2-oxopent-4-enoate hydratase activity
CBP35_RS13070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBP35_RS13095	COG0730	response to heat
CBP35_RS13125	COG1012	belongs to the aldehyde dehydrogenase family
CBP35_RS13130	COG0346	lactoylglutathione lyase activity
CBP35_RS13185	COG0543	2 iron, 2 sulfur cluster binding
CBP35_RS13185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CBP35_RS13190	COG2146	nitrite reductase [NAD(P)H] activity
CBP35_RS13210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBP35_RS13265	COG2159	amidohydrolase
CBP35_RS13270	COG2828	Protein conserved in bacteria
CBP35_RS13310	COG1192	Involved in chromosome partitioning
CBP35_RS13310	COG1192	Involved in chromosome partitioning
CBP35_RS13340	COG1396	sequence-specific DNA binding
CBP35_RS13535	COG0583	DNA-binding transcription factor activity
CBP35_RS13540	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS13555	COG0784	Response regulator, receiver
CBP35_RS13555	COG0835	chemotaxis
CBP35_RS13595	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CBP35_RS13600	COG0463	Glycosyl transferase, family 2
CBP35_RS13610	COG0617	tRNA 3'-terminal CCA addition
CBP35_RS13620	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CBP35_RS13625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CBP35_RS13635	COG0840	transmembrane signaling receptor activity
CBP35_RS13675	COG0268	Binds directly to 16S ribosomal RNA
CBP35_RS13685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CBP35_RS13690	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CBP35_RS13700	COG3706	GGDEF domain
CBP35_RS13720	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CBP35_RS13730	COG3483	tryptophan 2,3-dioxygenase activity
CBP35_RS13745	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CBP35_RS13750	COG2916	Histone family protein nucleoid-structuring protein H-NS
CBP35_RS13755	COG1253	flavin adenine dinucleotide binding
CBP35_RS13760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CBP35_RS13770	COG3245	cytochrome
CBP35_RS13780	COG4263	nitrous-oxide reductase activity
CBP35_RS13800	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
CBP35_RS13815	COG0513	Belongs to the DEAD box helicase family
CBP35_RS13820	COG2321	neutral zinc metallopeptidase
CBP35_RS13825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CBP35_RS13830	COG2423	ornithine cyclodeaminase activity
CBP35_RS13835	COG3706	GGDEF domain
CBP35_RS13840	COG0717	Belongs to the dCTP deaminase family
CBP35_RS13845	COG0402	S-adenosylhomocysteine deaminase activity
CBP35_RS13870	COG0537	adenosine 5'-monophosphoramidase activity
CBP35_RS13875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CBP35_RS13920	COG5001	Diguanylate cyclase
CBP35_RS13920	COG5002	protein histidine kinase activity
CBP35_RS13920	COG3447	MASE1 domain protein
CBP35_RS13990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CBP35_RS13995	COG0281	malic enzyme
CBP35_RS13995	COG0280	phosphate acetyltransferase
CBP35_RS14005	COG1116	anion transmembrane transporter activity
CBP35_RS14010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CBP35_RS14015	COG1752	Esterase of the alpha-beta hydrolase superfamily
CBP35_RS14020	COG2186	Transcriptional regulator
CBP35_RS14025	COG2610	gluconate transmembrane transporter activity
CBP35_RS14030	COG2084	Dehydrogenase
CBP35_RS14035	COG3395	kinase activity
CBP35_RS14040	COG0235	Class ii aldolase
CBP35_RS14045	COG3622	Belongs to the hyi family
CBP35_RS14055	COG0829	nickel cation binding
CBP35_RS14090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CBP35_RS14105	COG0831	urea catabolic process
CBP35_RS14115	COG0832	Belongs to the urease beta subunit family
CBP35_RS14120	COG0804	urea catabolic process
CBP35_RS14125	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CBP35_RS14130	COG0830	nickel cation binding
CBP35_RS14135	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CBP35_RS14140	COG0501	Belongs to the peptidase M48B family
CBP35_RS14145	COG1704	LemA family
CBP35_RS14185	COG0437	4 iron, 4 sulfur cluster binding
CBP35_RS14250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBP35_RS14250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CBP35_RS14270	COG0028	Belongs to the TPP enzyme family
CBP35_RS14295	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CBP35_RS14315	COG0602	queuosine metabolic process
CBP35_RS14320	COG0720	synthase
CBP35_RS14350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBP35_RS14365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CBP35_RS14370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CBP35_RS14375	COG0583	DNA-binding transcription factor activity
CBP35_RS14385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CBP35_RS14390	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CBP35_RS14405	COG0588	phosphoglycerate mutase activity
CBP35_RS14410	COG0793	Belongs to the peptidase S41A family
CBP35_RS14415	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CBP35_RS14425	COG2197	response regulator
CBP35_RS14430	COG4585	Histidine kinase
CBP35_RS14460	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CBP35_RS14465	COG0742	ribosomal rna small subunit methyltransferase
CBP35_RS14475	COG0612	Peptidase, M16
CBP35_RS14485	COG1324	tolerance protein
CBP35_RS14490	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBP35_RS14500	COG1999	signal sequence binding
CBP35_RS14505	COG0109	protoheme IX farnesyltransferase activity
CBP35_RS14530	COG1845	cytochrome c oxidase, subunit III
CBP35_RS14545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBP35_RS14565	COG1040	competence protein
CBP35_RS14570	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CBP35_RS14575	COG0583	DNA-binding transcription factor activity
CBP35_RS14620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CBP35_RS14625	COG0183	Belongs to the thiolase family
CBP35_RS14630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CBP35_RS14640	COG1414	Transcriptional regulator
CBP35_RS14665	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CBP35_RS14715	COG1178	ABC-type Fe3 transport system permease component
CBP35_RS14730	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CBP35_RS14735	COG0540	Belongs to the ATCase OTCase family
CBP35_RS14740	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CBP35_RS14745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CBP35_RS14750	COG1678	Uncharacterized ACR, COG1678
CBP35_RS14755	COG0415	Belongs to the DNA photolyase family
CBP35_RS14765	COG2198	Histidine kinase
CBP35_RS14765	COG0784	Response regulator, receiver
CBP35_RS14765	COG0643	Histidine kinase
CBP35_RS14765	COG2198	Histidine kinase
CBP35_RS14765	COG0784	Response regulator, receiver
CBP35_RS14765	COG0643	Histidine kinase
CBP35_RS14790	COG1773	rubredoxin
CBP35_RS14800	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CBP35_RS14810	COG0138	bifunctional purine biosynthesis protein purh
CBP35_RS14815	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CBP35_RS14830	COG1238	metal cluster binding
CBP35_RS14850	COG1136	(ABC) transporter
CBP35_RS14860	COG0012	GTP binding
CBP35_RS14865	COG0633	Ferredoxin
CBP35_RS14865	COG3217	Mosc domain protein beta barrel domain protein
CBP35_RS14885	COG1024	Enoyl-CoA hydratase
CBP35_RS14900	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CBP35_RS14905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CBP35_RS14910	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CBP35_RS14940	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CBP35_RS14950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CBP35_RS14965	COG2264	protein methyltransferase activity
CBP35_RS14970	COG0439	Biotin carboxylase
CBP35_RS14980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBP35_RS14990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBP35_RS15000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CBP35_RS15010	COG0312	modulator of DNA gyrase
CBP35_RS15015	COG3422	double-strand break repair
CBP35_RS15025	COG4585	Histidine kinase
CBP35_RS15030	COG2197	response regulator
CBP35_RS15040	COG0515	serine threonine protein kinase
CBP35_RS15040	COG2815	serine threonine protein kinase
CBP35_RS15045	COG3150	esterase
CBP35_RS15055	COG3474	cytochrome
CBP35_RS15065	COG1595	DNA-templated transcription, initiation
CBP35_RS15070	COG0557	exoribonuclease II activity
CBP35_RS15085	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CBP35_RS15100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CBP35_RS15115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CBP35_RS15145	COG1132	(ABC) transporter
CBP35_RS15150	COG0189	ligase activity
CBP35_RS15150	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBP35_RS15155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBP35_RS15155	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBP35_RS15160	COG3045	CreA protein
CBP35_RS15170	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS15185	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CBP35_RS15190	COG0459	protein refolding
CBP35_RS15200	COG1858	cytochrome C peroxidase
CBP35_RS15225	COG0800	Aldolase
CBP35_RS15230	COG0129	dihydroxy-acid dehydratase activity
CBP35_RS15245	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CBP35_RS15255	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CBP35_RS15290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS15300	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS15305	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS15315	COG0583	DNA-binding transcription factor activity
CBP35_RS15320	COG4608	Belongs to the ABC transporter superfamily
CBP35_RS15325	COG0444	Belongs to the ABC transporter superfamily
CBP35_RS15330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CBP35_RS15340	COG1473	amidohydrolase
CBP35_RS15360	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CBP35_RS15365	COG1765	OsmC-like protein
CBP35_RS15370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBP35_RS15445	COG0840	transmembrane signaling receptor activity
CBP35_RS15450	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CBP35_RS15455	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CBP35_RS15460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CBP35_RS15470	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CBP35_RS15475	COG1181	Belongs to the D-alanine--D-alanine ligase family
CBP35_RS15480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CBP35_RS15485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CBP35_RS15490	COG0772	Belongs to the SEDS family
CBP35_RS15495	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CBP35_RS15500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CBP35_RS15510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CBP35_RS15525	COG0275	rRNA processing
CBP35_RS15530	COG2001	Belongs to the MraZ family
CBP35_RS15535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CBP35_RS15540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CBP35_RS15555	COG0523	cobalamin synthesis protein
CBP35_RS15565	COG0789	Transcriptional regulator
CBP35_RS15570	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CBP35_RS15580	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CBP35_RS15590	COG1408	metallophosphoesterase
CBP35_RS15630	COG1566	PFAM secretion protein HlyD family protein
CBP35_RS15635	COG2814	Major facilitator Superfamily
CBP35_RS15645	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CBP35_RS15650	COG0471	metal ion transport
CBP35_RS15655	COG0501	Belongs to the peptidase M48B family
CBP35_RS15680	COG1126	abc transporter atp-binding protein
CBP35_RS15690	COG0765	amino acid transport
CBP35_RS15705	COG0583	DNA-binding transcription factor activity
CBP35_RS15715	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CBP35_RS15715	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CBP35_RS15720	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CBP35_RS15760	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CBP35_RS15765	COG5265	(ABC) transporter
CBP35_RS15785	COG1024	Enoyl-CoA hydratase
CBP35_RS15800	COG0183	Belongs to the thiolase family
CBP35_RS15810	COG1024	Enoyl-CoA hydratase
CBP35_RS15810	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBP35_RS15820	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS15830	COG1309	transcriptional regulator
CBP35_RS15840	COG0745	RESPONSE REGULATOR receiver
CBP35_RS15860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CBP35_RS15880	COG1086	Polysaccharide biosynthesis protein
CBP35_RS15890	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CBP35_RS15895	COG0482	sulfurtransferase activity
CBP35_RS15935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CBP35_RS15950	COG1091	dTDP-4-dehydrorhamnose reductase activity
CBP35_RS15955	COG1088	dTDP-glucose 4,6-dehydratase activity
CBP35_RS15980	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CBP35_RS15985	COG1652	LysM domain
CBP35_RS16010	COG0751	glycine-tRNA ligase activity
CBP35_RS16015	COG0752	glycyl-tRNA synthetase alpha subunit
CBP35_RS16035	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CBP35_RS16050	COG1522	sequence-specific DNA binding
CBP35_RS16055	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
CBP35_RS16070	COG3186	Phenylalanine-4-hydroxylase
CBP35_RS16100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CBP35_RS16135	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS16145	COG0037	tRNA processing
CBP35_RS16170	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CBP35_RS16170	COG1648	precorrin-2 dehydrogenase activity
CBP35_RS16175	COG2010	Cytochrome c
CBP35_RS16180	COG3391	amine dehydrogenase activity
CBP35_RS16210	COG1136	(ABC) transporter
CBP35_RS16215	COG4591	ABC-type transport system involved in lipoprotein release permease component
CBP35_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBP35_RS16250	COG0632	four-way junction helicase activity
CBP35_RS16255	COG1702	phosphate starvation-inducible protein PhoH
CBP35_RS16260	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CBP35_RS16275	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CBP35_RS16280	COG1845	cytochrome c oxidase, subunit III
CBP35_RS16285	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CBP35_RS16290	COG3346	SURF1 family
CBP35_RS16300	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CBP35_RS16305	COG0730	response to heat
CBP35_RS16315	COG0589	response to stress
CBP35_RS16320	COG1490	D-aminoacyl-tRNA deacylase activity
CBP35_RS16325	COG0513	Belongs to the DEAD box helicase family
CBP35_RS16340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CBP35_RS16345	COG1131	(ABC) transporter
CBP35_RS16355	COG0842	Transport permease protein
CBP35_RS16380	COG1250	3-hydroxyacyl-CoA dehydrogenase
CBP35_RS16385	COG1846	Transcriptional regulator
CBP35_RS16390	COG1764	response to oxidative stress
CBP35_RS16400	COG2815	serine threonine protein kinase
CBP35_RS16400	COG0515	serine threonine protein kinase
CBP35_RS16405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CBP35_RS16415	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS16420	COG0326	Molecular chaperone. Has ATPase activity
CBP35_RS16425	COG1187	pseudouridine synthase activity
CBP35_RS16445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBP35_RS16450	COG1022	Amp-dependent synthetase and ligase
CBP35_RS16505	COG3639	organic phosphonate transmembrane transporter activity
CBP35_RS16525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBP35_RS16530	COG3454	Phosphonate metabolism
CBP35_RS16540	COG4107	phosphonate C-P lyase system protein PhnK
CBP35_RS16550	COG3627	carbon phosphorus lyase activity
CBP35_RS16555	COG3626	phosphonate metabolism
CBP35_RS16565	COG3624	Phosphonate C-P lyase system protein PhnG
CBP35_RS16570	COG1609	Transcriptional regulator
CBP35_RS16580	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CBP35_RS16625	COG1473	amidohydrolase
CBP35_RS16640	COG0243	molybdopterin cofactor binding
CBP35_RS16650	COG1979	alcohol dehydrogenase
CBP35_RS16655	COG1309	transcriptional regulator
CBP35_RS16685	COG3945	hemerythrin HHE cation binding domain
CBP35_RS16710	COG0288	reversible hydration of carbon dioxide
CBP35_RS16715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CBP35_RS16720	COG2181	nitrate reductase activity
CBP35_RS16725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CBP35_RS16730	COG1140	nitrate reductase beta subunit
CBP35_RS16735	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CBP35_RS16740	COG2223	nitrite transmembrane transporter activity
CBP35_RS16750	COG2197	response regulator
CBP35_RS16755	COG0784	Response regulator, receiver
CBP35_RS16755	COG2205	protein histidine kinase activity
CBP35_RS16755	COG5002	protein histidine kinase activity
CBP35_RS16785	COG2733	membrane
CBP35_RS16805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBP35_RS16815	COG2084	Dehydrogenase
CBP35_RS16820	COG2823	Periplasmic or secreted lipoprotein
CBP35_RS16825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CBP35_RS16830	COG0792	nuclease activity
CBP35_RS16835	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CBP35_RS16855	COG0443	Heat shock 70 kDa protein
CBP35_RS16865	COG2204	response regulator
CBP35_RS16870	COG5000	phosphorelay sensor kinase activity
CBP35_RS16880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CBP35_RS16880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CBP35_RS16890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CBP35_RS16895	COG0085	RNA polymerase activity
CBP35_RS16900	COG0222	ribosome binding
CBP35_RS16905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CBP35_RS16910	COG0081	regulation of translation
CBP35_RS16915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CBP35_RS16925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CBP35_RS16935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBP35_RS16955	COG3385	transposase activity
CBP35_RS16990	COG4453	Protein conserved in bacteria
CBP35_RS17040	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBP35_RS17060	COG3174	membrane
CBP35_RS17140	COG2205	protein histidine kinase activity
CBP35_RS17160	COG0583	DNA-binding transcription factor activity
CBP35_RS17165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBP35_RS17170	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CBP35_RS17220	COG0582	viral genome integration into host DNA
CBP35_RS17355	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CBP35_RS17360	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CBP35_RS17365	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CBP35_RS17370	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CBP35_RS17375	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CBP35_RS17380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CBP35_RS17390	COG0356	it plays a direct role in the translocation of protons across the membrane
CBP35_RS17400	COG2921	Belongs to the UPF0250 family
CBP35_RS17405	COG0321	lipoyl(octanoyl) transferase activity
CBP35_RS17410	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CBP35_RS17420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CBP35_RS17425	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CBP35_RS17440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CBP35_RS17455	COG0456	acetyltransferase
CBP35_RS17460	COG0678	peroxiredoxin activity
CBP35_RS17465	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CBP35_RS17470	COG0255	Belongs to the universal ribosomal protein uL29 family
CBP35_RS17475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CBP35_RS17480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CBP35_RS17485	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CBP35_RS17490	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CBP35_RS17495	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CBP35_RS17500	COG0089	rRNA binding
CBP35_RS17505	COG0088	Forms part of the polypeptide exit tunnel
CBP35_RS17510	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CBP35_RS17515	COG0051	transcription antitermination factor activity, RNA binding
CBP35_RS17520	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CBP35_RS17525	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CBP35_RS17530	COG0049	tRNA binding
CBP35_RS17535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CBP35_RS17540	COG1686	Belongs to the peptidase S11 family
CBP35_RS17545	COG2945	thiolester hydrolase activity
CBP35_RS17560	COG1981	membrane
CBP35_RS17570	COG0598	Magnesium transport protein CorA
CBP35_RS17575	COG0412	Dienelactone hydrolase
CBP35_RS17580	COG2095	MarC family integral membrane protein
CBP35_RS17610	COG3237	CsbD-like
CBP35_RS17625	COG1127	ABC transporter
CBP35_RS17630	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CBP35_RS17645	COG0004	ammonium transporteR
CBP35_RS17655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CBP35_RS17660	COG0765	amino acid transport
CBP35_RS17675	COG0768	penicillin binding
CBP35_RS17685	COG1792	Involved in formation and maintenance of cell shape
CBP35_RS17690	COG1077	Cell shape determining protein MreB Mrl
CBP35_RS17695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBP35_RS17705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CBP35_RS17715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CBP35_RS17720	COG0708	Exodeoxyribonuclease III
CBP35_RS17725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBP35_RS17745	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CBP35_RS17830	COG1802	Transcriptional regulator
CBP35_RS17835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CBP35_RS17845	COG0501	Belongs to the peptidase M48B family
CBP35_RS17850	COG2211	Major facilitator Superfamily
CBP35_RS17855	COG0745	RESPONSE REGULATOR receiver
CBP35_RS17870	COG2070	2-Nitropropane dioxygenase
CBP35_RS17880	COG3307	-O-antigen
CBP35_RS17915	COG0747	negative chemotaxis
CBP35_RS17930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CBP35_RS17950	COG0386	Belongs to the glutathione peroxidase family
CBP35_RS17980	COG0247	lactate metabolic process
CBP35_RS17990	COG0277	FAD linked oxidase domain protein
CBP35_RS18005	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18010	COG2079	MmgE PrpD family protein
CBP35_RS18015	COG3180	Ammonia monooxygenase
CBP35_RS18030	COG2084	Dehydrogenase
CBP35_RS18055	COG2084	Dehydrogenase
CBP35_RS18065	COG0004	ammonium transporteR
CBP35_RS18070	COG0347	Belongs to the P(II) protein family
CBP35_RS18080	COG0606	chelatase, subunit chli
CBP35_RS18085	COG0840	transmembrane signaling receptor activity
CBP35_RS18115	COG1846	Transcriptional regulator
CBP35_RS18125	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CBP35_RS18155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBP35_RS18165	COG0646	methionine synthase
CBP35_RS18165	COG1410	methionine synthase
CBP35_RS18175	COG0583	DNA-binding transcription factor activity
CBP35_RS18180	COG2326	polyphosphate kinase activity
CBP35_RS18185	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CBP35_RS18190	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS18195	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS18225	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS18230	COG0183	Belongs to the thiolase family
CBP35_RS18240	COG1024	Enoyl-CoA hydratase
CBP35_RS18250	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS18255	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS18260	COG1024	Enoyl-CoA hydratase
CBP35_RS18270	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS18300	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18305	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CBP35_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
CBP35_RS18315	COG2030	dehydratase
CBP35_RS18320	COG1024	Enoyl-CoA hydratase
CBP35_RS18325	COG0427	acetyl-CoA hydrolase
CBP35_RS18330	COG0183	Belongs to the thiolase family
CBP35_RS18340	COG0318	PFAM AMP-dependent synthetase and ligase
CBP35_RS18360	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18370	COG0583	DNA-binding transcription factor activity
CBP35_RS18375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS18410	COG0724	RNA recognition motif
CBP35_RS18435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CBP35_RS18440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CBP35_RS18445	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CBP35_RS18470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CBP35_RS18475	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CBP35_RS18490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CBP35_RS18495	COG2267	carboxylic ester hydrolase activity
CBP35_RS18500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBP35_RS18505	COG2258	MOSC domain
CBP35_RS18510	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CBP35_RS18520	COG0850	regulation of cytokinetic process
CBP35_RS18525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CBP35_RS18540	COG0840	transmembrane signaling receptor activity
CBP35_RS18550	COG1183	phosphatidylcholine synthase activity
CBP35_RS18565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS18570	COG1024	Enoyl-CoA hydratase
CBP35_RS18575	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18580	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CBP35_RS18595	COG0583	DNA-binding transcription factor activity
CBP35_RS18600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CBP35_RS18605	COG2233	PERMEase
CBP35_RS18615	COG2050	protein possibly involved in aromatic compounds catabolism
CBP35_RS18620	COG2096	Adenosyltransferase
CBP35_RS18635	COG0277	FAD linked oxidase domain protein
CBP35_RS18640	COG1742	UPF0060 membrane protein
CBP35_RS18650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CBP35_RS18655	COG3639	organic phosphonate transmembrane transporter activity
CBP35_RS18690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CBP35_RS18710	COG1192	Involved in chromosome partitioning
CBP35_RS18720	COG0357	Ribosomal RNA small subunit methyltransferase G
CBP35_RS18725	COG0445	tRNA wobble uridine modification
CBP35_RS18740	COG0625	glutathione transferase activity
CBP35_RS18745	COG1902	pentaerythritol trinitrate reductase activity
CBP35_RS18750	COG0840	transmembrane signaling receptor activity
CBP35_RS18755	COG2217	Heavy metal translocating P-type atpase
CBP35_RS18760	COG2608	mercury ion transmembrane transporter activity
CBP35_RS18765	COG0789	Transcriptional regulator
CBP35_RS18805	COG1024	Enoyl-CoA hydratase
CBP35_RS18810	COG0183	Belongs to the thiolase family
CBP35_RS18815	COG1960	acyl-CoA dehydrogenase activity
CBP35_RS18820	COG1741	Belongs to the pirin family
CBP35_RS18825	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
CBP35_RS18830	COG2974	May be involved in recombination
CBP35_RS18855	COG0791	NLP P60 protein
CBP35_RS18895	COG2824	Alkylphosphonate utilization operon protein PhnA
CBP35_RS18920	COG0537	adenosine 5'-monophosphoramidase activity
CBP35_RS18975	COG0583	DNA-binding transcription factor activity
CBP35_RS18990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CBP35_RS18995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CBP35_RS19005	COG0732	type I restriction modification DNA specificity domain
CBP35_RS19010	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CBP35_RS19075	COG0778	Nitroreductase
CBP35_RS19095	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
CBP35_RS19155	COG1987	bacterial-type flagellum assembly
CBP35_RS19160	COG3012	SEC-C Motif Domain Protein
CBP35_RS19160	COG3318	Belongs to the UPF0149 family
CBP35_RS19165	COG4372	Transposase
CBP35_RS19285	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CBP35_RS19310	COG4974	Belongs to the 'phage' integrase family
CBP35_RS19335	COG1484	DNA-dependent DNA replication
CBP35_RS19340	COG4584	PFAM Integrase catalytic
CBP35_RS19385	COG0675	Transposase, IS605 OrfB family
CBP35_RS19415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CBP35_RS19420	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBP35_RS19535	COG0210	DNA helicase
CBP35_RS19540	COG2974	May be involved in recombination
CBP35_RS19555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CBP35_RS19595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CBP35_RS19615	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CBP35_RS19675	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CBP35_RS19685	COG2176	DNA-directed DNA polymerase activity
CBP35_RS19705	COG0358	DNA primase activity
CBP35_RS19720	COG0739	heme binding
CBP35_RS19785	COG0305	Participates in initiation and elongation during chromosome replication
CBP35_RS19915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBP35_RS19930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CBP35_RS19945	COG0840	transmembrane signaling receptor activity
CBP35_RS19955	COG0643	Histidine kinase
CBP35_RS19955	COG2198	Histidine kinase
CBP35_RS19970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBP35_RS19995	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CBP35_RS20000	COG4974	Belongs to the 'phage' integrase family
CBP35_RS20010	COG3415	Transposase
CBP35_RS20010	COG2801	Transposase and inactivated derivatives
CBP35_RS20020	COG1192	Involved in chromosome partitioning
CBP35_RS20100	COG2916	Histone family protein nucleoid-structuring protein H-NS
CBP35_RS20210	COG1396	sequence-specific DNA binding
CBP35_RS20210	COG3800	Transcriptional regulator
CBP35_RS20285	COG0372	Belongs to the citrate synthase family
CBP35_RS20300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CBP35_RS20310	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CBP35_RS20345	COG2159	amidohydrolase
CBP35_RS20380	COG0667	Aldo Keto reductase
CBP35_RS20405	COG3181	Tripartite tricarboxylate transporter family receptor
CBP35_RS20445	COG0372	Belongs to the citrate synthase family
CBP35_RS20510	COG1063	alcohol dehydrogenase
CBP35_RS20560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CBP35_RS20565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CBP35_RS20580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CBP35_RS20590	COG1309	transcriptional regulator
CBP35_RS20595	COG1309	transcriptional regulator
CBP35_RS20610	COG4974	Belongs to the 'phage' integrase family
CBP35_RS20665	COG1396	sequence-specific DNA binding
CBP35_RS20670	COG3550	peptidyl-serine autophosphorylation
CBP35_RS20745	COG1595	DNA-templated transcription, initiation
CBP35_RS20755	COG2226	methyltransferase
CBP35_RS20805	COG0583	DNA-binding transcription factor activity
CBP35_RS20840	COG0789	Transcriptional regulator
CBP35_RS20890	COG1742	UPF0060 membrane protein
CBP35_RS20895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CBP35_RS20900	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CBP35_RS20930	COG2003	Belongs to the UPF0758 family
CBP35_RS20950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CBP35_RS21005	COG3850	Histidine kinase
CBP35_RS21010	COG2197	response regulator
CBP35_RS21050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CBP35_RS21240	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
CBP35_RS21280	COG3657	addiction module killer protein
CBP35_RS21325	COG0629	single-stranded DNA binding