locus-tag	class	description
FRC90_RS00025	COG0583	DNA-binding transcription factor activity
FRC90_RS00040	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FRC90_RS00045	COG1126	abc transporter atp-binding protein
FRC90_RS00050	COG0765	amino acid transport
FRC90_RS00055	COG0765	amino acid transport
FRC90_RS00075	COG0646	methionine synthase
FRC90_RS00075	COG1410	methionine synthase
FRC90_RS00130	COG0583	DNA-binding transcription factor activity
FRC90_RS00140	COG0840	transmembrane signaling receptor activity
FRC90_RS00145	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS00150	COG4191	Histidine kinase
FRC90_RS00160	COG0606	chelatase, subunit chli
FRC90_RS00170	COG0347	Belongs to the P(II) protein family
FRC90_RS00175	COG0004	ammonium transporteR
FRC90_RS00220	COG0277	FAD linked oxidase domain protein
FRC90_RS00230	COG0247	lactate metabolic process
FRC90_RS00260	COG0386	Belongs to the glutathione peroxidase family
FRC90_RS00270	COG0477	Major facilitator Superfamily
FRC90_RS00275	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FRC90_RS00285	COG0747	negative chemotaxis
FRC90_RS00305	COG0625	glutathione transferase activity
FRC90_RS00310	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC90_RS00355	COG1215	transferase activity, transferring glycosyl groups
FRC90_RS00375	COG0477	Major facilitator Superfamily
FRC90_RS00385	COG0745	RESPONSE REGULATOR receiver
FRC90_RS00390	COG2211	Major facilitator Superfamily
FRC90_RS00410	COG0501	Belongs to the peptidase M48B family
FRC90_RS00415	COG0471	metal ion transport
FRC90_RS00420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC90_RS00440	COG0583	DNA-binding transcription factor activity
FRC90_RS00445	COG2814	Major facilitator Superfamily
FRC90_RS00455	COG0708	Exodeoxyribonuclease III
FRC90_RS00460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FRC90_RS00470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC90_RS00475	COG0154	amidase activity
FRC90_RS00480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC90_RS00485	COG1077	Cell shape determining protein MreB Mrl
FRC90_RS00495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FRC90_RS00500	COG0768	penicillin binding
FRC90_RS00515	COG0765	amino acid transport
FRC90_RS00520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS00525	COG1760	l-serine dehydratase
FRC90_RS00545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC90_RS00550	COG1127	ABC transporter
FRC90_RS00575	COG3237	CsbD-like
FRC90_RS00595	COG4452	Inner membrane protein CreD
FRC90_RS00600	COG2205	protein histidine kinase activity
FRC90_RS00605	COG0745	RESPONSE REGULATOR receiver
FRC90_RS00610	COG2095	MarC family integral membrane protein
FRC90_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS00620	COG0412	Dienelactone hydrolase
FRC90_RS00630	COG1566	PFAM secretion protein HlyD family protein
FRC90_RS00640	COG1846	Transcriptional regulator
FRC90_RS00645	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC90_RS00645	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_RS00650	COG0598	Magnesium transport protein CorA
FRC90_RS00660	COG1981	membrane
FRC90_RS00675	COG2945	thiolester hydrolase activity
FRC90_RS00680	COG1686	Belongs to the peptidase S11 family
FRC90_RS00685	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FRC90_RS00690	COG0049	tRNA binding
FRC90_RS00695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FRC90_RS00700	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC90_RS00705	COG0051	transcription antitermination factor activity, RNA binding
FRC90_RS00710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FRC90_RS00715	COG0088	Forms part of the polypeptide exit tunnel
FRC90_RS00720	COG0089	rRNA binding
FRC90_RS00725	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FRC90_RS00730	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FRC90_RS00735	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FRC90_RS00740	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FRC90_RS00745	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FRC90_RS00750	COG0255	Belongs to the universal ribosomal protein uL29 family
FRC90_RS00755	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FRC90_RS00760	COG0678	peroxiredoxin activity
FRC90_RS00770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC90_RS00785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC90_RS00790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC90_RS00805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FRC90_RS00810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FRC90_RS00815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FRC90_RS00820	COG2205	protein histidine kinase activity
FRC90_RS00825	COG0745	RESPONSE REGULATOR receiver
FRC90_RS00845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FRC90_RS00850	COG0321	lipoyl(octanoyl) transferase activity
FRC90_RS00855	COG2921	Belongs to the UPF0250 family
FRC90_RS00865	COG0356	it plays a direct role in the translocation of protons across the membrane
FRC90_RS00875	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FRC90_RS00880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FRC90_RS00885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FRC90_RS00890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FRC90_RS00895	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FRC90_RS00900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC90_RS00905	COG1793	dna ligase
FRC90_RS00905	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FRC90_RS00910	COG1793	dna ligase
FRC90_RS00915	COG1201	RNA secondary structure unwinding
FRC90_RS00965	COG3245	cytochrome
FRC90_RS00980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_RS00985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_RS01070	COG0121	glutamine amidotransferase
FRC90_RS01075	COG2814	Major facilitator Superfamily
FRC90_RS01080	COG1942	4-Oxalocrotonate Tautomerase
FRC90_RS01095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FRC90_RS01125	COG0018	arginyl-trna synthetase
FRC90_RS01135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FRC90_RS01145	COG1137	ATPase activity
FRC90_RS01150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC90_RS01155	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FRC90_RS01175	COG4178	(ABC) transporter
FRC90_RS01185	COG0653	protein targeting
FRC90_RS01190	COG0659	secondary active sulfate transmembrane transporter activity
FRC90_RS01205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FRC90_RS01225	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FRC90_RS01240	COG2967	ApaG domain
FRC90_RS01245	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FRC90_RS01255	COG0546	phosphoglycolate phosphatase activity
FRC90_RS01275	COG2207	Transcriptional regulator
FRC90_RS01305	COG4794	Type iii secretion
FRC90_RS01310	COG4790	Type iii secretion
FRC90_RS01325	COG4789	Type iii secretion
FRC90_RS01330	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC90_RS01455	COG0500	methyltransferase
FRC90_RS01460	COG0741	lytic transglycosylase activity
FRC90_RS01460	COG1196	nuclear chromosome segregation
FRC90_RS01460	COG0739	heme binding
FRC90_RS01485	COG0512	Glutamine amidotransferase of anthranilate synthase
FRC90_RS01490	COG1280	lysine exporter protein (LysE YggA)
FRC90_RS01495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC90_RS01505	COG0134	indole-3-glycerol-phosphate synthase activity
FRC90_RS01510	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FRC90_RS01550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FRC90_RS01560	COG0783	Belongs to the Dps family
FRC90_RS01565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC90_RS01580	COG0463	Glycosyl transferase, family 2
FRC90_RS01595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FRC90_RS01605	COG3842	ATPase activity
FRC90_RS01610	COG3842	ATPase activity
FRC90_RS01620	COG0395	ABC-type sugar transport system, permease component
FRC90_RS01640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FRC90_RS01645	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FRC90_RS01650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FRC90_RS01655	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FRC90_RS01660	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FRC90_RS01665	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FRC90_RS01670	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FRC90_RS01675	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FRC90_RS01680	COG1841	ribosomal large subunit assembly
FRC90_RS01685	COG0200	Binds to the 23S rRNA
FRC90_RS01690	COG0201	protein transport
FRC90_RS01695	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FRC90_RS01700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FRC90_RS01705	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FRC90_RS01710	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FRC90_RS01715	COG0202	RNA polymerase activity
FRC90_RS01720	COG0203	ribosomal protein L17
FRC90_RS01730	COG0443	Heat shock 70 kDa protein
FRC90_RS01735	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC90_RS01740	COG0792	nuclease activity
FRC90_RS01745	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FRC90_RS01750	COG2823	Periplasmic or secreted lipoprotein
FRC90_RS01755	COG2084	Dehydrogenase
FRC90_RS01765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC90_RS01790	COG2733	membrane
FRC90_RS01810	COG0277	FAD linked oxidase domain protein
FRC90_RS01820	COG0583	DNA-binding transcription factor activity
FRC90_RS01840	COG1285	pathogenesis
FRC90_RS01850	COG3850	Histidine kinase
FRC90_RS01855	COG2197	response regulator
FRC90_RS01870	COG4771	TonB-dependent receptor
FRC90_RS01885	COG2223	nitrite transmembrane transporter activity
FRC90_RS01890	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FRC90_RS01895	COG1140	nitrate reductase beta subunit
FRC90_RS01900	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FRC90_RS01905	COG2181	nitrate reductase activity
FRC90_RS01910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_RS01915	COG0288	reversible hydration of carbon dioxide
FRC90_RS01930	COG3945	hemerythrin HHE cation binding domain
FRC90_RS01940	COG0477	Major facilitator Superfamily
FRC90_RS01985	COG1272	protein, Hemolysin III
FRC90_RS02000	COG3706	GGDEF domain
FRC90_RS02010	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_RS02015	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_RS02025	COG0129	dihydroxy-acid dehydratase activity
FRC90_RS02030	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS02040	COG0583	DNA-binding transcription factor activity
FRC90_RS02045	COG1741	Belongs to the pirin family
FRC90_RS02050	COG1335	isochorismatase
FRC90_RS02090	COG0243	molybdopterin cofactor binding
FRC90_RS02105	COG1473	amidohydrolase
FRC90_RS02115	COG0840	transmembrane signaling receptor activity
FRC90_RS02130	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_RS02140	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_RS02195	COG3267	Type II secretory pathway component ExeA
FRC90_RS02195	COG3409	Peptidoglycan-binding domain 1 protein
FRC90_RS02200	COG3266	domain, Protein
FRC90_RS02215	COG4269	membrane
FRC90_RS02250	COG0625	glutathione transferase activity
FRC90_RS02255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FRC90_RS02265	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FRC90_RS02270	COG1649	PFAM Uncharacterised BCR, COG1649
FRC90_RS02290	COG5002	protein histidine kinase activity
FRC90_RS02290	COG3447	MASE1 domain protein
FRC90_RS02290	COG5001	Diguanylate cyclase
FRC90_RS02295	COG0523	cobalamin synthesis protein
FRC90_RS02310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FRC90_RS02315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FRC90_RS02320	COG2001	Belongs to the MraZ family
FRC90_RS02325	COG0275	rRNA processing
FRC90_RS02330	COG3116	cell division
FRC90_RS02340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_RS02345	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FRC90_RS02350	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FRC90_RS02355	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FRC90_RS02360	COG0772	Belongs to the SEDS family
FRC90_RS02365	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FRC90_RS02370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC90_RS02375	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC90_RS02380	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FRC90_RS02390	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FRC90_RS02395	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FRC90_RS02405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FRC90_RS02410	COG0840	transmembrane signaling receptor activity
FRC90_RS02425	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FRC90_RS02430	COG0575	Belongs to the CDS family
FRC90_RS02455	COG1414	Transcriptional regulator
FRC90_RS02460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_RS02465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FRC90_RS02475	COG0557	exoribonuclease II activity
FRC90_RS02485	COG3150	esterase
FRC90_RS02490	COG0772	Belongs to the SEDS family
FRC90_RS02495	COG0154	amidase activity
FRC90_RS02500	COG0312	modulator of DNA gyrase
FRC90_RS02510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC90_RS02520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC90_RS02530	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC90_RS02535	COG0511	ligase activity, forming carbon-carbon bonds
FRC90_RS02540	COG0439	Biotin carboxylase
FRC90_RS02545	COG2264	protein methyltransferase activity
FRC90_RS02555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC90_RS02565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FRC90_RS02600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FRC90_RS02610	COG2204	response regulator
FRC90_RS02620	COG2205	protein histidine kinase activity
FRC90_RS02625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC90_RS02650	COG0431	NADPH-dependent FMN reductase
FRC90_RS02655	COG3829	transcription factor binding
FRC90_RS02660	COG1024	Enoyl-CoA hydratase
FRC90_RS02675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC90_RS02685	COG0012	GTP binding
FRC90_RS02695	COG1125	glycine betaine transport
FRC90_RS02695	COG0517	IMP dehydrogenase activity
FRC90_RS02705	COG1238	metal cluster binding
FRC90_RS02715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_RS02720	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FRC90_RS02725	COG0138	bifunctional purine biosynthesis protein purh
FRC90_RS02735	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FRC90_RS02740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FRC90_RS02740	COG0352	thiamine-phosphate diphosphorylase activity
FRC90_RS02740	COG0351	phosphomethylpyrimidine kinase
FRC90_RS02745	COG1773	rubredoxin
FRC90_RS02760	COG0835	chemotaxis
FRC90_RS02765	COG0840	transmembrane signaling receptor activity
FRC90_RS02770	COG2198	Histidine kinase
FRC90_RS02770	COG0643	Histidine kinase
FRC90_RS02775	COG0415	Belongs to the DNA photolyase family
FRC90_RS02780	COG1678	Uncharacterized ACR, COG1678
FRC90_RS02785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FRC90_RS02790	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FRC90_RS02795	COG0540	Belongs to the ATCase OTCase family
FRC90_RS02810	COG3842	ATPase activity
FRC90_RS02815	COG1178	ABC-type Fe3 transport system permease component
FRC90_RS02865	COG4970	Tfp pilus assembly protein FimT
FRC90_RS02885	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FRC90_RS02890	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_RS02895	COG1765	OsmC-like protein
FRC90_RS02900	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FRC90_RS02920	COG1473	amidohydrolase
FRC90_RS02925	COG0747	negative chemotaxis
FRC90_RS02930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_RS02935	COG0444	Belongs to the ABC transporter superfamily
FRC90_RS02940	COG4608	Belongs to the ABC transporter superfamily
FRC90_RS02945	COG0840	transmembrane signaling receptor activity
FRC90_RS02960	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FRC90_RS02965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FRC90_RS02970	COG0166	Belongs to the GPI family
FRC90_RS02975	COG0459	protein refolding
FRC90_RS02980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FRC90_RS02995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FRC90_RS03030	COG2226	methyltransferase
FRC90_RS03035	COG0438	transferase activity, transferring glycosyl groups
FRC90_RS03045	COG0367	asparagine synthase
FRC90_RS03050	COG0438	transferase activity, transferring glycosyl groups
FRC90_RS03055	COG0367	asparagine synthase
FRC90_RS03075	COG1216	Glycosyl transferase, family 2
FRC90_RS03085	COG1309	transcriptional regulator
FRC90_RS03090	COG0493	'glutamate synthase
FRC90_RS03100	COG1953	Uracil, thiamine, allantoin
FRC90_RS03135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FRC90_RS03135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FRC90_RS03140	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC90_RS03155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FRC90_RS03165	COG1560	Kdo2-lipid A biosynthetic process
FRC90_RS03175	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FRC90_RS03185	COG1333	cytochrome c biogenesis protein
FRC90_RS03190	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FRC90_RS03195	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FRC90_RS03200	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FRC90_RS03230	COG1965	Belongs to the frataxin family
FRC90_RS03270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FRC90_RS03275	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FRC90_RS03280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FRC90_RS03300	COG0067	glutamate synthase
FRC90_RS03300	COG0070	glutamate synthase
FRC90_RS03300	COG0069	glutamate synthase activity
FRC90_RS03310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS03315	COG0765	amino acid transport
FRC90_RS03320	COG1126	abc transporter atp-binding protein
FRC90_RS03325	COG1127	ABC transporter
FRC90_RS03330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC90_RS03335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FRC90_RS03340	COG2853	Lipoprotein
FRC90_RS03360	COG1131	(ABC) transporter
FRC90_RS03365	COG0842	Transport permease protein
FRC90_RS03370	COG5007	Belongs to the BolA IbaG family
FRC90_RS03375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FRC90_RS03380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FRC90_RS03385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FRC90_RS03415	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FRC90_RS03420	COG0131	Imidazoleglycerol-phosphate dehydratase
FRC90_RS03430	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FRC90_RS03450	COG0438	transferase activity, transferring glycosyl groups
FRC90_RS03480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FRC90_RS03485	COG1301	dicarboxylic acid transport
FRC90_RS03495	COG0107	imidazoleglycerol-phosphate synthase activity
FRC90_RS03500	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FRC90_RS03505	COG0140	phosphoribosyl-ATP diphosphatase activity
FRC90_RS03520	COG0537	adenosine 5'-monophosphoramidase activity
FRC90_RS03525	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC90_RS03530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC90_RS03535	COG0805	protein transport
FRC90_RS03555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FRC90_RS03575	COG0714	Associated with various cellular activities
FRC90_RS03580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_RS03585	COG0084	hydrolase, TatD family'
FRC90_RS03595	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC90_RS03600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC90_RS03660	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS03665	COG0840	transmembrane signaling receptor activity
FRC90_RS03670	COG0829	nickel cation binding
FRC90_RS03690	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC90_RS03715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS03720	COG1116	anion transmembrane transporter activity
FRC90_RS03735	COG0280	phosphate acetyltransferase
FRC90_RS03735	COG0281	malic enzyme
FRC90_RS03755	COG1953	Uracil, thiamine, allantoin
FRC90_RS03760	COG2186	Transcriptional regulator
FRC90_RS03765	COG0840	transmembrane signaling receptor activity
FRC90_RS03770	COG1301	dicarboxylic acid transport
FRC90_RS03805	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC90_RS03820	COG2186	Transcriptional regulator
FRC90_RS03830	COG0405	Gamma-glutamyltransferase
FRC90_RS03870	COG0251	oxidation-reduction process
FRC90_RS03890	COG5001	Diguanylate cyclase
FRC90_RS03890	COG5002	protein histidine kinase activity
FRC90_RS03890	COG3447	MASE1 domain protein
FRC90_RS03905	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS03925	COG3845	ABC transporter
FRC90_RS03930	COG4603	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS03955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FRC90_RS03965	COG2366	antibiotic biosynthetic process
FRC90_RS03970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC90_RS03980	COG0402	S-adenosylhomocysteine deaminase activity
FRC90_RS03985	COG0717	Belongs to the dCTP deaminase family
FRC90_RS04000	COG2321	neutral zinc metallopeptidase
FRC90_RS04005	COG0513	Belongs to the DEAD box helicase family
FRC90_RS04010	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FRC90_RS04015	COG2916	Histone family protein nucleoid-structuring protein H-NS
FRC90_RS04020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FRC90_RS04040	COG3483	tryptophan 2,3-dioxygenase activity
FRC90_RS04050	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FRC90_RS04055	COG1522	sequence-specific DNA binding
FRC90_RS04060	COG0727	PFAM Uncharacterised protein family (UPF0153)
FRC90_RS04085	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FRC90_RS04090	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FRC90_RS04100	COG0579	oxidoreductase
FRC90_RS04105	COG0268	Binds directly to 16S ribosomal RNA
FRC90_RS04110	COG0728	peptidoglycan biosynthetic process
FRC90_RS04120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC90_RS04120	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC90_RS04130	COG3022	response to hydroperoxide
FRC90_RS04135	COG1530	ribonuclease E activity
FRC90_RS04160	COG0616	signal peptide processing
FRC90_RS04160	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FRC90_RS04165	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC90_RS04170	COG0424	maF-like protein
FRC90_RS04175	COG1399	metal-binding, possibly nucleic acid-binding protein
FRC90_RS04180	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FRC90_RS04185	COG0416	fatty acid biosynthetic process
FRC90_RS04190	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FRC90_RS04195	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FRC90_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS04205	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC90_RS04210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FRC90_RS04235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_RS04240	COG0481	GTPase activity
FRC90_RS04245	COG0681	Belongs to the peptidase S26 family
FRC90_RS04255	COG0571	ribonuclease III activity
FRC90_RS04260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FRC90_RS04265	COG1381	Involved in DNA repair and RecF pathway recombination
FRC90_RS04270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FRC90_RS04280	COG1472	Belongs to the glycosyl hydrolase 3 family
FRC90_RS04285	COG3064	Membrane
FRC90_RS04295	COG2203	Gaf domain
FRC90_RS04295	COG3706	GGDEF domain
FRC90_RS04295	COG4251	negative regulation of phosphorylation
FRC90_RS04295	COG5001	Diguanylate cyclase
FRC90_RS04300	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FRC90_RS04325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FRC90_RS04340	COG0762	integral membrane protein
FRC90_RS04345	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FRC90_RS04350	COG0159	tryptophan synthase activity
FRC90_RS04355	COG0133	tryptophan synthase activity
FRC90_RS04360	COG0135	phosphoribosylanthranilate isomerase activity
FRC90_RS04365	COG0101	tRNA pseudouridine synthase activity
FRC90_RS04375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FRC90_RS04385	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_RS04390	COG0066	3-isopropylmalate dehydratase activity
FRC90_RS04400	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FRC90_RS04410	COG0484	heat shock protein binding
FRC90_RS04415	COG0443	Heat shock 70 kDa protein
FRC90_RS04420	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FRC90_RS04425	COG0360	Binds together with S18 to 16S ribosomal RNA
FRC90_RS04435	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FRC90_RS04440	COG0359	binds to the 23S rRNA
FRC90_RS04455	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FRC90_RS04460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRC90_RS04525	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC90_RS04530	COG0436	Aminotransferase
FRC90_RS04545	COG1763	Mo-molybdopterin cofactor biosynthetic process
FRC90_RS04550	COG0303	'Molybdopterin
FRC90_RS04555	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FRC90_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_RS04585	COG0314	molybdopterin synthase activity
FRC90_RS04590	COG0542	response to heat
FRC90_RS04610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FRC90_RS04620	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_RS04635	COG0436	Aminotransferase
FRC90_RS04640	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FRC90_RS04645	COG1185	polyribonucleotide nucleotidyltransferase activity
FRC90_RS04650	COG3321	synthase
FRC90_RS04650	COG0604	alcohol dehydrogenase
FRC90_RS04650	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS04655	COG0149	triose-phosphate isomerase activity
FRC90_RS04670	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_RS04675	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_RS04680	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_RS04685	COG0649	NAD binding
FRC90_RS04690	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FRC90_RS04695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRC90_RS04700	COG1034	ATP synthesis coupled electron transport
FRC90_RS04705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FRC90_RS04710	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC90_RS04720	COG0713	ATP synthesis coupled electron transport
FRC90_RS04735	COG1007	ATP synthesis coupled electron transport
FRC90_RS04795	COG0457	Tetratricopeptide repeat
FRC90_RS04795	COG0463	Glycosyl transferase, family 2
FRC90_RS04815	COG0071	Belongs to the small heat shock protein (HSP20) family
FRC90_RS04820	COG1136	(ABC) transporter
FRC90_RS04825	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FRC90_RS04830	COG0702	epimerase
FRC90_RS04835	COG1733	regulation of RNA biosynthetic process
FRC90_RS04840	COG2267	carboxylic ester hydrolase activity
FRC90_RS04845	COG0584	glycerophosphoryl diester phosphodiesterase
FRC90_RS04855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FRC90_RS04860	COG0586	Pfam SNARE associated Golgi protein
FRC90_RS04865	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_RS04880	COG0860	N-Acetylmuramoyl-L-alanine amidase
FRC90_RS04885	COG0802	atpase or kinase
FRC90_RS04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FRC90_RS04925	COG4974	Belongs to the 'phage' integrase family
FRC90_RS04930	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS04935	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC90_RS04940	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC90_RS04945	COG2833	Protein of unknown function (DUF455)
FRC90_RS04955	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FRC90_RS04965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FRC90_RS04970	COG0148	phosphopyruvate hydratase activity
FRC90_RS04990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FRC90_RS04995	COG0504	CTP synthase activity
FRC90_RS05000	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FRC90_RS05005	COG0756	dUTP diphosphatase activity
FRC90_RS05015	COG1047	Peptidyl-prolyl cis-trans
FRC90_RS05020	COG2850	peptidyl-arginine hydroxylation
FRC90_RS05035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FRC90_RS05040	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FRC90_RS05045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_RS05070	COG0741	lytic transglycosylase activity
FRC90_RS05080	COG0840	transmembrane signaling receptor activity
FRC90_RS05085	COG0840	transmembrane signaling receptor activity
FRC90_RS05090	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FRC90_RS05125	COG2308	Evidence 4 Homologs of previously reported genes of
FRC90_RS05145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC90_RS05155	COG4628	conserved protein (DUF2132)
FRC90_RS05165	COG0657	acetylesterase activity
FRC90_RS05170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_RS05195	COG4774	siderophore transport
FRC90_RS05240	COG3634	alkyl hydroperoxide reductase activity
FRC90_RS05265	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FRC90_RS05280	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FRC90_RS05305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS05320	COG0583	DNA-binding transcription factor activity
FRC90_RS05325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS05340	COG4948	Mandelate Racemase Muconate Lactonizing
FRC90_RS05385	COG0840	transmembrane signaling receptor activity
FRC90_RS05390	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC90_RS05395	COG0358	DNA primase activity
FRC90_RS05400	COG3300	MHYT domain
FRC90_RS05400	COG5001	Diguanylate cyclase
FRC90_RS05405	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS05410	COG0405	Gamma-glutamyltransferase
FRC90_RS05415	COG3540	Alkaline phosphatase
FRC90_RS05425	COG0604	alcohol dehydrogenase
FRC90_RS05425	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS05425	COG3321	synthase
FRC90_RS05430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FRC90_RS05435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FRC90_RS05445	COG0564	pseudouridine synthase activity
FRC90_RS05450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FRC90_RS05455	COG1187	pseudouridine synthase activity
FRC90_RS05460	COG0105	UTP biosynthetic process
FRC90_RS05465	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FRC90_RS05470	COG3063	Type IV pilus biogenesis stability protein PilW
FRC90_RS05480	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FRC90_RS05485	COG0124	histidyl-tRNA synthetase
FRC90_RS05500	COG1160	GTP binding
FRC90_RS05505	COG1923	regulation of RNA biosynthetic process
FRC90_RS05510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FRC90_RS05515	COG0330	HflC and HflK could
FRC90_RS05520	COG0330	HflC and HflK could
FRC90_RS05525	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FRC90_RS05530	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FRC90_RS05535	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FRC90_RS05565	COG1187	pseudouridine synthase activity
FRC90_RS05595	COG0174	glutamine synthetase
FRC90_RS05605	COG3852	Histidine kinase
FRC90_RS05610	COG2204	response regulator
FRC90_RS05620	COG0708	Exodeoxyribonuclease III
FRC90_RS05635	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FRC90_RS05645	COG0277	FAD linked oxidase domain protein
FRC90_RS05655	COG1295	ribonuclease BN
FRC90_RS05660	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FRC90_RS05685	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC90_RS05690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FRC90_RS05695	COG0740	serine-type endopeptidase activity
FRC90_RS05700	COG0544	peptidyl-prolyl cis-trans isomerase activity
FRC90_RS05710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_RS05720	COG1562	ergosterol biosynthetic process
FRC90_RS05750	COG0631	protein serine/threonine phosphatase activity
FRC90_RS05765	COG2885	chlorophyll binding
FRC90_RS05830	COG1451	nucleotide metabolic process
FRC90_RS05835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS05840	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC90_RS05845	COG2080	2 iron, 2 sulfur cluster binding
FRC90_RS05850	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FRC90_RS05865	COG0114	fumarate hydratase activity
FRC90_RS05875	COG0745	RESPONSE REGULATOR receiver
FRC90_RS05880	COG2205	protein histidine kinase activity
FRC90_RS05885	COG2113	Glycine betaine
FRC90_RS05890	COG4176	ABC-type proline glycine betaine transport system permease component
FRC90_RS05895	COG4175	Glycine betaine
FRC90_RS05905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC90_RS05925	COG4654	Cytochrome c, class I
FRC90_RS05935	COG0129	dihydroxy-acid dehydratase activity
FRC90_RS05950	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FRC90_RS05955	COG1802	Transcriptional regulator
FRC90_RS05975	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS05985	COG0589	response to stress
FRC90_RS05995	COG2217	Heavy metal translocating P-type atpase
FRC90_RS06005	COG3278	Belongs to the heme-copper respiratory oxidase family
FRC90_RS06040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC90_RS06045	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC90_RS06055	COG3437	response regulator, receiver
FRC90_RS06075	COG4206	TonB-dependent receptor
FRC90_RS06080	COG1797	cobyrinic acid a,c-diamide synthase activity
FRC90_RS06095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC90_RS06100	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC90_RS06105	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FRC90_RS06110	COG0778	Nitroreductase
FRC90_RS06115	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC90_RS06145	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS06150	COG1492	cobalamin metabolic process
FRC90_RS06155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FRC90_RS06180	COG0477	Major facilitator Superfamily
FRC90_RS06200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FRC90_RS06205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_RS06210	COG2900	Belongs to the SlyX family
FRC90_RS06225	COG0513	Belongs to the DEAD box helicase family
FRC90_RS06250	COG1959	2 iron, 2 sulfur cluster binding
FRC90_RS06255	COG0583	DNA-binding transcription factor activity
FRC90_RS06270	COG0560	Phosphoserine phosphatase
FRC90_RS06280	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC90_RS06290	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FRC90_RS06295	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC90_RS06295	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC90_RS06300	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC90_RS06300	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC90_RS06320	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS06330	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC90_RS06370	COG0693	protein deglycase activity
FRC90_RS06380	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FRC90_RS06385	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC90_RS06400	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FRC90_RS06415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS06420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_RS06440	COG1446	asparaginase
FRC90_RS06445	COG4172	Belongs to the ABC transporter superfamily
FRC90_RS06455	COG0601	transmembrane transport
FRC90_RS06460	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_RS06480	COG0322	excinuclease ABC activity
FRC90_RS06520	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FRC90_RS06705	COG3728	DNA packaging
FRC90_RS06705	COG5484	DNA packaging
FRC90_RS06885	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC90_RS06895	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS06900	COG0028	Belongs to the TPP enzyme family
FRC90_RS06905	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS06925	COG2267	carboxylic ester hydrolase activity
FRC90_RS06935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC90_RS06980	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_RS06985	COG2207	Transcriptional regulator
FRC90_RS06995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FRC90_RS07025	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FRC90_RS07025	COG4651	solute:proton antiporter activity
FRC90_RS07035	COG0513	Belongs to the DEAD box helicase family
FRC90_RS07040	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC90_RS07045	COG0488	(ABC) transporter
FRC90_RS07060	COG3191	aminopeptidase activity
FRC90_RS07085	COG2132	Multicopper oxidase
FRC90_RS07115	COG0789	Transcriptional regulator
FRC90_RS07140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FRC90_RS07140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FRC90_RS07145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS07150	COG0052	Belongs to the universal ribosomal protein uS2 family
FRC90_RS07155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FRC90_RS07160	COG0528	UMP kinase activity
FRC90_RS07165	COG0233	cytoplasmic translational termination
FRC90_RS07175	COG0575	Belongs to the CDS family
FRC90_RS07180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FRC90_RS07185	COG0750	zinc metalloprotease
FRC90_RS07200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_RS07205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC90_RS07210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_RS07215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC90_RS07220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FRC90_RS07225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC90_RS07230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS07235	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS07240	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS07245	COG0583	DNA-binding transcription factor activity
FRC90_RS07255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FRC90_RS07260	COG0308	aminopeptidase N
FRC90_RS07270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC90_RS07280	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC90_RS07285	COG0667	Aldo Keto reductase
FRC90_RS07290	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FRC90_RS07295	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FRC90_RS07305	COG3577	Aspartyl protease
FRC90_RS07310	COG1666	GTP binding
FRC90_RS07320	COG0137	argininosuccinate synthase activity
FRC90_RS07325	COG3123	guanosine phosphorylase activity
FRC90_RS07335	COG1393	Belongs to the ArsC family
FRC90_RS07340	COG0285	dihydrofolate synthase activity
FRC90_RS07350	COG1286	toxin biosynthetic process
FRC90_RS07365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_RS07405	COG2814	Major facilitator Superfamily
FRC90_RS07410	COG2814	Major facilitator Superfamily
FRC90_RS07435	COG2183	response to ionizing radiation
FRC90_RS07450	COG1454	alcohol dehydrogenase
FRC90_RS07460	COG0657	acetylesterase activity
FRC90_RS07475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FRC90_RS07480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FRC90_RS07495	COG0084	hydrolase, TatD family'
FRC90_RS07505	COG1132	(ABC) transporter
FRC90_RS07510	COG0823	Involved in the tonB-independent uptake of proteins
FRC90_RS07515	COG2885	chlorophyll binding
FRC90_RS07525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FRC90_RS07545	COG2423	ornithine cyclodeaminase activity
FRC90_RS07610	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS07610	COG2010	Cytochrome c
FRC90_RS07620	COG0779	Required for maturation of 30S ribosomal subunits
FRC90_RS07625	COG0195	Participates in both transcription termination and antitermination
FRC90_RS07630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FRC90_RS07635	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FRC90_RS07640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FRC90_RS07650	COG1253	flavin adenine dinucleotide binding
FRC90_RS07655	COG1024	Enoyl-CoA hydratase
FRC90_RS07675	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FRC90_RS07685	COG2914	Belongs to the UPF0125 (RnfH) family
FRC90_RS07710	COG0519	Catalyzes the synthesis of GMP from XMP
FRC90_RS07710	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC90_RS07755	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FRC90_RS07785	COG0583	DNA-binding transcription factor activity
FRC90_RS07795	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS07815	COG3209	COG3209 Rhs family protein
FRC90_RS07860	COG2226	methyltransferase
FRC90_RS07865	COG0492	ferredoxin-NADP+ reductase activity
FRC90_RS07880	COG1278	Cold shock
FRC90_RS07885	COG0494	nUDIX hydrolase
FRC90_RS07920	COG4774	siderophore transport
FRC90_RS07925	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC90_RS07935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC90_RS07945	COG0506	proline dehydrogenase activity
FRC90_RS07945	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC90_RS07945	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC90_RS07960	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FRC90_RS07970	COG0670	Belongs to the BI1 family
FRC90_RS07975	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FRC90_RS08015	COG0405	Gamma-glutamyltransferase
FRC90_RS08020	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC90_RS08025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC90_RS08050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FRC90_RS08085	COG2212	antiporter activity
FRC90_RS08095	COG0651	ATP synthesis coupled electron transport
FRC90_RS08100	COG1006	Multisubunit Na H antiporter MnhC subunit
FRC90_RS08105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC90_RS08105	COG2111	Na H antiporter
FRC90_RS08110	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FRC90_RS08120	COG0776	regulation of translation
FRC90_RS08130	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FRC90_RS08135	COG0287	Prephenate dehydrogenase
FRC90_RS08140	COG0077	Prephenate dehydratase
FRC90_RS08140	COG1605	Chorismate mutase
FRC90_RS08145	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FRC90_RS08160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_RS08280	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FRC90_RS08290	COG4166	transmembrane transport
FRC90_RS08295	COG4174	ABC transporter (Permease)
FRC90_RS08300	COG4239	(ABC) transporter, permease
FRC90_RS08305	COG4172	Belongs to the ABC transporter superfamily
FRC90_RS08310	COG5001	Diguanylate cyclase
FRC90_RS08310	COG5002	protein histidine kinase activity
FRC90_RS08310	COG3447	MASE1 domain protein
FRC90_RS08315	COG0628	permease
FRC90_RS08320	COG0567	Dehydrogenase, E1 component
FRC90_RS08325	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC90_RS08330	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC90_RS08335	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FRC90_RS08350	COG1199	ATP-dependent helicase activity
FRC90_RS08365	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FRC90_RS08370	COG0542	response to heat
FRC90_RS08375	COG2951	lytic endotransglycosylase activity
FRC90_RS08380	COG2925	Exonuclease
FRC90_RS08390	COG3284	Transcriptional regulator
FRC90_RS08410	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_RS08415	COG0484	heat shock protein binding
FRC90_RS08450	COG0402	S-adenosylhomocysteine deaminase activity
FRC90_RS08465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FRC90_RS08480	COG0625	glutathione transferase activity
FRC90_RS08505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FRC90_RS08510	COG0277	FAD linked oxidase domain protein
FRC90_RS08530	COG0433	COG0433 Predicted ATPase
FRC90_RS08535	COG0217	transcriptional regulatory protein
FRC90_RS08540	COG0151	Belongs to the GarS family
FRC90_RS08545	COG0408	coproporphyrinogen oxidase activity
FRC90_RS08550	COG0799	negative regulation of ribosome biogenesis
FRC90_RS08555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FRC90_RS08565	COG0424	maF-like protein
FRC90_RS08570	COG1530	ribonuclease E activity
FRC90_RS08610	COG0210	DNA helicase
FRC90_RS08625	COG3593	DNA synthesis involved in DNA repair
FRC90_RS08640	COG2205	protein histidine kinase activity
FRC90_RS08645	COG0596	Alpha beta hydrolase
FRC90_RS08660	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS08670	COG1024	Enoyl-CoA hydratase
FRC90_RS08675	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS08685	COG0683	leucine binding
FRC90_RS08720	COG0436	Aminotransferase
FRC90_RS08725	COG0583	DNA-binding transcription factor activity
FRC90_RS08745	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FRC90_RS08785	COG0589	response to stress
FRC90_RS08805	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS08810	COG0564	pseudouridine synthase activity
FRC90_RS08820	COG0545	Peptidyl-prolyl cis-trans isomerase
FRC90_RS08825	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC90_RS08825	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC90_RS08830	COG0509	glycine decarboxylation via glycine cleavage system
FRC90_RS08835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FRC90_RS08850	COG4120	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS08905	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FRC90_RS08915	COG1252	NADH dehydrogenase
FRC90_RS08940	COG0835	chemotaxis
FRC90_RS08945	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS08955	COG0583	DNA-binding transcription factor activity
FRC90_RS08970	COG0347	Belongs to the P(II) protein family
FRC90_RS08980	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FRC90_RS09000	COG1595	DNA-templated transcription, initiation
FRC90_RS09010	COG0028	Belongs to the TPP enzyme family
FRC90_RS09015	COG0440	acetolactate synthase activity
FRC90_RS09020	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FRC90_RS09025	COG1183	phosphatidylcholine synthase activity
FRC90_RS09030	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_RS09040	COG1414	Transcriptional regulator
FRC90_RS09045	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FRC90_RS09050	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FRC90_RS09065	COG2832	Protein of unknown function (DUF454)
FRC90_RS09070	COG0242	peptide deformylase activity
FRC90_RS09075	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FRC90_RS09080	COG0024	Methionine aminopeptidase
FRC90_RS09085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FRC90_RS09085	COG0047	phosphoribosylformylglycinamidine synthase activity
FRC90_RS09100	COG5001	Diguanylate cyclase
FRC90_RS09100	COG3300	MHYT domain
FRC90_RS09105	COG2354	Protein conserved in bacteria
FRC90_RS09110	COG3047	cAMP biosynthetic process
FRC90_RS09125	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FRC90_RS09130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FRC90_RS09140	COG0823	Involved in the tonB-independent uptake of proteins
FRC90_RS09140	COG1506	peptidase
FRC90_RS09140	COG4946	Tricorn protease homolog
FRC90_RS09155	COG0826	peptidase U32
FRC90_RS09180	COG1619	proteins homologs of microcin C7 resistance protein MccF
FRC90_RS09195	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS09210	COG1024	Enoyl-CoA hydratase
FRC90_RS09215	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_RS09230	COG2022	thiamine diphosphate biosynthetic process
FRC90_RS09245	COG0351	phosphomethylpyrimidine kinase
FRC90_RS09305	COG0492	ferredoxin-NADP+ reductase activity
FRC90_RS09310	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FRC90_RS09315	COG0529	Catalyzes the synthesis of activated sulfate
FRC90_RS09315	COG2895	sulfate adenylyltransferase (ATP) activity
FRC90_RS09320	COG0175	sulfate reduction
FRC90_RS09335	COG0730	response to heat
FRC90_RS09350	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FRC90_RS09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS09355	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FRC90_RS09365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC90_RS09375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_RS09385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS09390	COG1116	anion transmembrane transporter activity
FRC90_RS09400	COG0583	DNA-binding transcription factor activity
FRC90_RS09420	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC90_RS09430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FRC90_RS09435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_RS09440	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FRC90_RS09440	COG0493	'glutamate synthase
FRC90_RS09445	COG0583	DNA-binding transcription factor activity
FRC90_RS09450	COG1741	Belongs to the pirin family
FRC90_RS09460	COG1741	Belongs to the pirin family
FRC90_RS09465	COG1054	Belongs to the UPF0176 family
FRC90_RS09505	COG4181	ATPase activity
FRC90_RS09510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC90_RS09515	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FRC90_RS09520	COG0667	Aldo Keto reductase
FRC90_RS09535	COG0642	Histidine kinase
FRC90_RS09545	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS09595	COG5002	protein histidine kinase activity
FRC90_RS09600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FRC90_RS09605	COG1011	Hydrolase
FRC90_RS09620	COG0517	IMP dehydrogenase activity
FRC90_RS09620	COG1125	glycine betaine transport
FRC90_RS09625	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FRC90_RS09635	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FRC90_RS09640	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FRC90_RS09645	COG0741	lytic transglycosylase activity
FRC90_RS09670	COG0557	exoribonuclease II activity
FRC90_RS09675	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS09680	COG0297	glycogen (starch) synthase activity
FRC90_RS09700	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FRC90_RS09720	COG0784	Response regulator, receiver
FRC90_RS09720	COG4191	Histidine kinase
FRC90_RS09725	COG2205	protein histidine kinase activity
FRC90_RS09730	COG2205	protein histidine kinase activity
FRC90_RS09740	COG2172	sigma factor antagonist activity
FRC90_RS09745	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC90_RS09750	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC90_RS09760	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS09770	COG2188	Transcriptional regulator
FRC90_RS09775	COG2986	histidine ammonia-lyase
FRC90_RS09780	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FRC90_RS09795	COG1228	amidohydrolase
FRC90_RS09825	COG0688	phosphatidylethanolamine metabolic process
FRC90_RS09830	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC90_RS10010	COG4695	Portal protein
FRC90_RS10015	COG0740	serine-type endopeptidase activity
FRC90_RS10065	COG1196	nuclear chromosome segregation
FRC90_RS10135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_RS10145	COG2917	probably involved in intracellular septation
FRC90_RS10150	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC90_RS10155	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FRC90_RS10160	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS10170	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS10180	COG0411	ABC transporter
FRC90_RS10205	COG3706	GGDEF domain
FRC90_RS10220	COG1024	Enoyl-CoA hydratase
FRC90_RS10220	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_RS10225	COG0183	Belongs to the thiolase family
FRC90_RS10230	COG2050	protein possibly involved in aromatic compounds catabolism
FRC90_RS10235	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS10255	COG2130	NADP-dependent
FRC90_RS10260	COG2153	protein acetylation
FRC90_RS10280	COG1840	ABC-type Fe3 transport system, periplasmic component
FRC90_RS10290	COG0697	spore germination
FRC90_RS10295	COG1522	sequence-specific DNA binding
FRC90_RS10310	COG2224	Isocitrate lyase
FRC90_RS10315	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FRC90_RS10320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FRC90_RS10325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FRC90_RS10330	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FRC90_RS10335	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FRC90_RS10340	COG0072	phenylalanine-tRNA ligase activity
FRC90_RS10340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_RS10345	COG0776	regulation of translation
FRC90_RS10350	COG0789	Transcriptional regulator
FRC90_RS10375	COG1132	(ABC) transporter
FRC90_RS10380	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FRC90_RS10390	COG1742	UPF0060 membrane protein
FRC90_RS10405	COG1196	nuclear chromosome segregation
FRC90_RS10415	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FRC90_RS10485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FRC90_RS10510	COG3048	D-serine ammonia-lyase activity
FRC90_RS10515	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS10520	COG0154	amidase activity
FRC90_RS10540	COG1739	Uncharacterized protein family UPF0029
FRC90_RS10555	COG0840	transmembrane signaling receptor activity
FRC90_RS10570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS10580	COG0556	nucleotide-excision repair
FRC90_RS10585	COG1959	2 iron, 2 sulfur cluster binding
FRC90_RS10590	COG1104	cysteine desulfurase activity
FRC90_RS10595	COG0822	iron-sulfur transferase activity
FRC90_RS10605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FRC90_RS10610	COG0443	Heat shock 70 kDa protein
FRC90_RS10615	COG0633	Ferredoxin
FRC90_RS10640	COG0579	oxidoreductase
FRC90_RS10660	COG0167	dihydroorotate dehydrogenase activity
FRC90_RS10665	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FRC90_RS10680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FRC90_RS10685	COG4566	intracellular signal transduction
FRC90_RS10695	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FRC90_RS10700	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC90_RS10705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC90_RS10730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FRC90_RS10735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_RS10745	COG0515	serine threonine protein kinase
FRC90_RS10775	COG3243	poly(R)-hydroxyalkanoic acid synthase
FRC90_RS10780	COG0183	Belongs to the thiolase family
FRC90_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS10790	COG0488	(ABC) transporter
FRC90_RS10795	COG2890	protein-(glutamine-N5) methyltransferase activity
FRC90_RS10800	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC90_RS10810	COG2171	N-acyltransferase activity
FRC90_RS10820	COG0840	transmembrane signaling receptor activity
FRC90_RS10825	COG2878	Part of a membrane complex involved in electron transport
FRC90_RS10845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC90_RS10870	COG3039	Transposase
FRC90_RS10885	COG0840	transmembrane signaling receptor activity
FRC90_RS10955	COG1802	Transcriptional regulator
FRC90_RS10960	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC90_RS10960	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC90_RS10970	COG1703	isobutyryl-CoA mutase activity
FRC90_RS10975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_RS10985	COG4770	biotin carboxylase activity
FRC90_RS11005	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FRC90_RS11050	COG5002	protein histidine kinase activity
FRC90_RS11065	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_RS11080	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FRC90_RS11085	COG0583	DNA-binding transcription factor activity
FRC90_RS11090	COG2814	Major facilitator Superfamily
FRC90_RS11100	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FRC90_RS11105	COG2011	ABC-type metal ion transport system permease component
FRC90_RS11125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC90_RS11145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FRC90_RS11150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FRC90_RS11155	COG4208	sulfate ABC transporter
FRC90_RS11160	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FRC90_RS11165	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FRC90_RS11190	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FRC90_RS11190	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC90_RS11195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS11205	COG1643	Atp-dependent helicase
FRC90_RS11215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC90_RS11220	COG0252	asparaginase activity
FRC90_RS11230	COG0563	adenylate kinase activity
FRC90_RS11235	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FRC90_RS11240	COG2835	tetraacyldisaccharide 4'-kinase activity
FRC90_RS11245	COG1663	tetraacyldisaccharide 4'-kinase activity
FRC90_RS11250	COG0848	biopolymer transport protein
FRC90_RS11255	COG0811	peptide transport
FRC90_RS11260	COG1570	exodeoxyribonuclease VII activity
FRC90_RS11265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FRC90_RS11295	COG0625	glutathione transferase activity
FRC90_RS11300	COG1942	4-Oxalocrotonate Tautomerase
FRC90_RS11315	COG2814	Major facilitator Superfamily
FRC90_RS11320	COG0789	Transcriptional regulator
FRC90_RS11360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC90_RS11365	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS11375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FRC90_RS11385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS11400	COG2721	sulfolactate sulfo-lyase activity
FRC90_RS11415	COG4772	TonB-dependent receptor
FRC90_RS11420	COG2032	superoxide dismutase activity
FRC90_RS11435	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS11460	COG1113	amino acid transport
FRC90_RS11470	COG0505	Belongs to the CarA family
FRC90_RS11475	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FRC90_RS11480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC90_RS11495	COG1534	Rna-binding protein
FRC90_RS11500	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FRC90_RS11505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC90_RS11515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FRC90_RS11545	COG0248	Ppx GppA phosphatase
FRC90_RS11550	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FRC90_RS11555	COG0573	inorganic phosphate transmembrane transporter activity
FRC90_RS11560	COG0581	inorganic phosphate transmembrane transporter activity
FRC90_RS11565	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FRC90_RS11570	COG0704	Plays a role in the regulation of phosphate uptake
FRC90_RS11585	COG0534	Mate efflux family protein
FRC90_RS11595	COG0254	rRNA binding
FRC90_RS11600	COG0420	3'-5' exonuclease activity
FRC90_RS11605	COG0419	ATPase involved in DNA repair
FRC90_RS11610	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FRC90_RS11625	COG1074	ATP-dependent DNA helicase activity
FRC90_RS11630	COG2081	HI0933 family
FRC90_RS11645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FRC90_RS11650	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FRC90_RS11655	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FRC90_RS11675	COG0741	lytic transglycosylase activity
FRC90_RS11675	COG1388	LysM domain
FRC90_RS11680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC90_RS11685	COG2226	methyltransferase
FRC90_RS11690	COG0328	RNA-DNA hybrid ribonuclease activity
FRC90_RS11705	COG0303	'Molybdopterin
FRC90_RS11715	COG0746	molybdenum cofactor guanylyltransferase activity
FRC90_RS11720	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FRC90_RS11745	COG1012	belongs to the aldehyde dehydrogenase family
FRC90_RS11770	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FRC90_RS11785	COG0587	DNA-directed DNA polymerase activity
FRC90_RS11790	COG2982	Protein involved in outer membrane biogenesis
FRC90_RS11795	COG0564	pseudouridine synthase activity
FRC90_RS11810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FRC90_RS11820	COG0431	NADPH-dependent FMN reductase
FRC90_RS11825	COG0583	DNA-binding transcription factor activity
FRC90_RS11870	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS11875	COG0346	lactoylglutathione lyase activity
FRC90_RS11885	COG0800	Aldolase
FRC90_RS11895	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS11900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_RS11905	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_RS11910	COG3265	gluconokinase activity
FRC90_RS11915	COG1609	Transcriptional regulator
FRC90_RS11940	COG0259	pyridoxamine-phosphate oxidase activity
FRC90_RS11955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS11960	COG4771	TonB-dependent receptor
FRC90_RS11985	COG1136	(ABC) transporter
FRC90_RS11995	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC90_RS12000	COG1309	transcriptional regulator
FRC90_RS12020	COG1042	CoA-binding domain protein
FRC90_RS12020	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC90_RS12020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC90_RS12070	COG2133	pyrroloquinoline quinone binding
FRC90_RS12075	COG0791	NLP P60 protein
FRC90_RS12120	COG3209	COG3209 Rhs family protein
FRC90_RS12140	COG3728	DNA packaging
FRC90_RS12140	COG5484	DNA packaging
FRC90_RS12190	COG0527	aspartate kinase activity
FRC90_RS12195	COG0037	tRNA processing
FRC90_RS12210	COG0215	cysteine-tRNA ligase activity
FRC90_RS12265	COG1522	sequence-specific DNA binding
FRC90_RS12285	COG3384	dioxygenase
FRC90_RS12300	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FRC90_RS12310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC90_RS12325	COG1309	transcriptional regulator
FRC90_RS12365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_RS12395	COG0840	transmembrane signaling receptor activity
FRC90_RS12425	COG0564	pseudouridine synthase activity
FRC90_RS12430	COG1285	pathogenesis
FRC90_RS12445	COG2814	Major facilitator Superfamily
FRC90_RS12465	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FRC90_RS12480	COG5002	protein histidine kinase activity
FRC90_RS12495	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC90_RS12505	COG2918	glutathione biosynthetic process
FRC90_RS12515	COG3386	PFAM SMP-30 Gluconolaconase
FRC90_RS12535	COG1879	ABC-type sugar transport system periplasmic component
FRC90_RS12540	COG4213	ABC transporter substrate-binding protein
FRC90_RS12550	COG4214	carbohydrate transport
FRC90_RS12560	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS12565	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS12580	COG3734	2-keto-3-deoxy-galactonokinase
FRC90_RS12585	COG0800	Aldolase
FRC90_RS12590	COG4948	Mandelate Racemase Muconate Lactonizing
FRC90_RS12595	COG1289	transmembrane transporter activity
FRC90_RS12620	COG0745	RESPONSE REGULATOR receiver
FRC90_RS12630	COG2202	Pas domain
FRC90_RS12630	COG2205	protein histidine kinase activity
FRC90_RS12640	COG0633	Ferredoxin
FRC90_RS12655	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FRC90_RS12660	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_RS12665	COG0436	Aminotransferase
FRC90_RS12670	COG0824	Thioesterase
FRC90_RS12690	COG0477	Major facilitator Superfamily
FRC90_RS12695	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FRC90_RS12700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FRC90_RS12705	COG1845	cytochrome c oxidase, subunit III
FRC90_RS12710	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FRC90_RS12740	COG0826	peptidase U32
FRC90_RS12755	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FRC90_RS12760	COG1049	propionate catabolic process, 2-methylcitrate cycle
FRC90_RS12775	COG4106	trans-aconitate 2-methyltransferase activity
FRC90_RS12780	COG0039	L-malate dehydrogenase activity
FRC90_RS12785	COG2188	Transcriptional regulator
FRC90_RS12800	COG1053	succinate dehydrogenase
FRC90_RS12805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FRC90_RS12810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FRC90_RS12815	COG0372	Belongs to the citrate synthase family
FRC90_RS12830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC90_RS12835	COG4977	sequence-specific DNA binding
FRC90_RS12845	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC90_RS12850	COG2194	sulfuric ester hydrolase activity
FRC90_RS12860	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_RS12870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_RS12875	COG0601	transmembrane transport
FRC90_RS12885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS12905	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_RS12915	COG1522	sequence-specific DNA binding
FRC90_RS12920	COG1473	amidohydrolase
FRC90_RS12965	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS12980	COG3264	Mechanosensitive ion channel
FRC90_RS12980	COG1511	domain protein
FRC90_RS12995	COG1024	Enoyl-CoA hydratase
FRC90_RS13000	COG0123	including yeast histone deacetylase and acetoin utilization protein
FRC90_RS13005	COG0714	Associated with various cellular activities
FRC90_RS13020	COG2951	lytic endotransglycosylase activity
FRC90_RS13050	COG0683	leucine binding
FRC90_RS13065	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FRC90_RS13070	COG0683	leucine binding
FRC90_RS13090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC90_RS13095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS13100	COG1116	anion transmembrane transporter activity
FRC90_RS13105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FRC90_RS13120	COG0724	RNA recognition motif
FRC90_RS13130	COG0626	cystathionine gamma-synthase activity
FRC90_RS13145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC90_RS13170	COG0194	GDP metabolic process
FRC90_RS13175	COG3958	Transketolase
FRC90_RS13180	COG3959	Transketolase, thiamine diphosphate binding domain
FRC90_RS13185	COG2223	nitrite transmembrane transporter activity
FRC90_RS13200	COG0745	RESPONSE REGULATOR receiver
FRC90_RS13210	COG0840	transmembrane signaling receptor activity
FRC90_RS13215	COG0643	Histidine kinase
FRC90_RS13215	COG2198	Histidine kinase
FRC90_RS13235	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_RS13240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_RS13245	COG0516	GMP reductase activity
FRC90_RS13245	COG0517	IMP dehydrogenase activity
FRC90_RS13250	COG0840	transmembrane signaling receptor activity
FRC90_RS13260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC90_RS13275	COG0840	transmembrane signaling receptor activity
FRC90_RS13280	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FRC90_RS13290	COG0243	molybdopterin cofactor binding
FRC90_RS13295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC90_RS13305	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FRC90_RS13305	COG5297	Belongs to the glycosyl hydrolase family 6
FRC90_RS13310	COG1607	acyl-coa hydrolase
FRC90_RS13315	COG0288	reversible hydration of carbon dioxide
FRC90_RS13330	COG2081	HI0933 family
FRC90_RS13335	COG0640	Transcriptional regulator
FRC90_RS13355	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FRC90_RS13360	COG1610	YqeY-like protein
FRC90_RS13365	COG0625	glutathione transferase activity
FRC90_RS13375	COG0583	DNA-binding transcription factor activity
FRC90_RS13380	COG0473	3-isopropylmalate dehydrogenase activity
FRC90_RS13385	COG1752	Esterase of the alpha-beta hydrolase superfamily
FRC90_RS13390	COG0477	Major facilitator Superfamily
FRC90_RS13405	COG2721	sulfolactate sulfo-lyase activity
FRC90_RS13420	COG0312	modulator of DNA gyrase
FRC90_RS13425	COG3028	Belongs to the UPF0307 family
FRC90_RS13430	COG0521	Mo-molybdopterin cofactor biosynthetic process
FRC90_RS13435	COG1045	serine acetyltransferase
FRC90_RS13445	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC90_RS13450	COG4555	ABC transporter
FRC90_RS13465	COG0483	inositol monophosphate 1-phosphatase activity
FRC90_RS13485	COG1132	(ABC) transporter
FRC90_RS13495	COG3437	response regulator, receiver
FRC90_RS13500	COG0784	Response regulator, receiver
FRC90_RS13500	COG2205	protein histidine kinase activity
FRC90_RS13500	COG5002	protein histidine kinase activity
FRC90_RS13555	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FRC90_RS13560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FRC90_RS13575	COG3209	COG3209 Rhs family protein
FRC90_RS13600	COG3447	MASE1 domain protein
FRC90_RS13600	COG5002	protein histidine kinase activity
FRC90_RS13600	COG5001	Diguanylate cyclase
FRC90_RS13605	COG1968	undecaprenyl-diphosphatase activity
FRC90_RS13635	COG3275	phosphorelay sensor kinase activity
FRC90_RS13640	COG3279	Response regulator of the LytR AlgR family
FRC90_RS13645	COG1280	lysine exporter protein (LysE YggA)
FRC90_RS13655	COG4133	protoheme IX ABC transporter activity
FRC90_RS13665	COG3585	molybdate ion transport
FRC90_RS13665	COG2005	Transcriptional regulator
FRC90_RS13685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FRC90_RS13690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FRC90_RS13695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FRC90_RS13700	COG0366	Alpha amylase catalytic
FRC90_RS13705	COG0366	Alpha amylase catalytic
FRC90_RS13710	COG0668	transmembrane transport
FRC90_RS13730	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FRC90_RS13735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FRC90_RS13740	COG0142	geranyltranstransferase activity
FRC90_RS13745	COG1722	exodeoxyribonuclease VII activity
FRC90_RS13800	COG0628	permease
FRC90_RS13805	COG1289	transmembrane transporter activity
FRC90_RS13810	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FRC90_RS13815	COG0181	hydroxymethylbilane synthase activity
FRC90_RS13835	COG0488	(ABC) transporter
FRC90_RS13845	COG0501	Belongs to the peptidase M48B family
FRC90_RS13850	COG0525	valine-tRNA ligase activity
FRC90_RS13855	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FRC90_RS13865	COG0425	Belongs to the sulfur carrier protein TusA family
FRC90_RS13870	COG2816	NAD+ diphosphatase activity
FRC90_RS13915	COG0583	DNA-binding transcription factor activity
FRC90_RS13920	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS13925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS13965	COG0617	tRNA 3'-terminal CCA addition
FRC90_RS13975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC90_RS13980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FRC90_RS14005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FRC90_RS14025	COG0840	transmembrane signaling receptor activity
FRC90_RS14030	COG1304	FMN binding
FRC90_RS14040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC90_RS14045	COG0840	transmembrane signaling receptor activity
FRC90_RS14080	COG0165	Argininosuccinate lyase
FRC90_RS14085	COG3275	phosphorelay sensor kinase activity
FRC90_RS14095	COG0165	Argininosuccinate lyase
FRC90_RS14105	COG0412	Dienelactone hydrolase
FRC90_RS14135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS14140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS14180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FRC90_RS14265	COG0516	GMP reductase activity
FRC90_RS14325	COG2204	response regulator
FRC90_RS14330	COG5002	protein histidine kinase activity
FRC90_RS14335	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC90_RS14350	COG2814	Major facilitator Superfamily
FRC90_RS14355	COG5001	Diguanylate cyclase
FRC90_RS14355	COG3447	MASE1 domain protein
FRC90_RS14355	COG5002	protein histidine kinase activity
FRC90_RS14360	COG0513	Belongs to the DEAD box helicase family
FRC90_RS14365	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FRC90_RS14375	COG2154	pterin-4-alpha-carbinolamine dehydratase
FRC90_RS14380	COG1162	GTPase activity
FRC90_RS14385	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC90_RS14395	COG0335	large ribosomal subunit rRNA binding
FRC90_RS14400	COG0336	Belongs to the RNA methyltransferase TrmD family
FRC90_RS14405	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FRC90_RS14410	COG0228	four-way junction DNA binding
FRC90_RS14425	COG0306	phosphate transporter
FRC90_RS14430	COG1392	Phosphate transport regulator
FRC90_RS14435	COG2885	chlorophyll binding
FRC90_RS14435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FRC90_RS14455	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS14460	COG0840	transmembrane signaling receptor activity
FRC90_RS14465	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FRC90_RS14470	COG1573	uracil-dna glycosylase
FRC90_RS14480	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FRC90_RS14485	COG1674	ftsk spoiiie
FRC90_RS14490	COG0492	ferredoxin-NADP+ reductase activity
FRC90_RS14495	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FRC90_RS14500	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FRC90_RS14505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_RS14520	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC90_RS14520	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_RS14525	COG3866	Pectate lyase
FRC90_RS14540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC90_RS14545	COG3132	Protein of unknown function, DUF480
FRC90_RS14550	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS14570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_RS14585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_RS14595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS14605	COG0196	riboflavin kinase activity
FRC90_RS14615	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FRC90_RS14630	COG1609	Transcriptional regulator
FRC90_RS14640	COG4149	molybdate abc transporter
FRC90_RS14645	COG1177	transmembrane transport
FRC90_RS14655	COG3842	ATPase activity
FRC90_RS14660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FRC90_RS14670	COG1283	sodium-dependent phosphate transmembrane transporter activity
FRC90_RS14685	COG0583	DNA-binding transcription factor activity
FRC90_RS14715	COG0697	spore germination
FRC90_RS14745	COG3209	COG3209 Rhs family protein
FRC90_RS14755	COG3209	COG3209 Rhs family protein
FRC90_RS14820	COG2814	Major facilitator Superfamily
FRC90_RS14865	COG1301	dicarboxylic acid transport
FRC90_RS14870	COG5599	Phosphatase
FRC90_RS14895	COG3038	cytochrome b561
FRC90_RS14910	COG4770	biotin carboxylase activity
FRC90_RS14915	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FRC90_RS14920	COG4336	lyase activity
FRC90_RS14925	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FRC90_RS14930	COG2814	Major facilitator Superfamily
FRC90_RS14950	COG2205	protein histidine kinase activity
FRC90_RS14955	COG1304	FMN binding
FRC90_RS14975	COG5001	Diguanylate cyclase
FRC90_RS14990	COG0831	urea catabolic process
FRC90_RS15000	COG0832	Belongs to the urease beta subunit family
FRC90_RS15005	COG0804	urea catabolic process
FRC90_RS15015	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FRC90_RS15020	COG0830	nickel cation binding
FRC90_RS15025	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FRC90_RS15040	COG0464	growth
FRC90_RS15055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FRC90_RS15060	COG5000	phosphorelay sensor kinase activity
FRC90_RS15060	COG5002	protein histidine kinase activity
FRC90_RS15080	COG2199	diguanylate cyclase activity
FRC90_RS15080	COG2200	EAL domain
FRC90_RS15080	COG2202	Pas domain
FRC90_RS15100	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC90_RS15105	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC90_RS15130	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC90_RS15130	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC90_RS15175	COG0784	Response regulator, receiver
FRC90_RS15175	COG4191	Histidine kinase
FRC90_RS15180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_RS15205	COG1595	DNA-templated transcription, initiation
FRC90_RS15220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC90_RS15225	COG4221	oxidoreductase activity
FRC90_RS15240	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC90_RS15245	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FRC90_RS15265	COG1561	YicC-like family, N-terminal region
FRC90_RS15270	COG0194	GDP metabolic process
FRC90_RS15275	COG1758	RNA polymerase activity
FRC90_RS15280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC90_RS15305	COG3693	PFAM glycoside hydrolase, family 10
FRC90_RS15310	COG2197	response regulator
FRC90_RS15320	COG1420	regulation of RNA biosynthetic process
FRC90_RS15325	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FRC90_RS15330	COG0497	DNA recombination
FRC90_RS15335	COG1660	Displays ATPase and GTPase activities
FRC90_RS15340	COG1194	a g-specific adenine glycosylase
FRC90_RS15350	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC90_RS15365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FRC90_RS15375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FRC90_RS15380	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FRC90_RS15385	COG0193	aminoacyl-tRNA hydrolase activity
FRC90_RS15390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FRC90_RS15400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_RS15405	COG0444	Belongs to the ABC transporter superfamily
FRC90_RS15410	COG4608	Belongs to the ABC transporter superfamily
FRC90_RS15420	COG0747	negative chemotaxis
FRC90_RS15450	COG1609	Transcriptional regulator
FRC90_RS15480	COG0302	gtp cyclohydrolase
FRC90_RS15485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_RS15495	COG0745	RESPONSE REGULATOR receiver
FRC90_RS15500	COG0494	nUDIX hydrolase
FRC90_RS15510	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FRC90_RS15530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FRC90_RS15545	COG2226	methyltransferase
FRC90_RS15570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_RS15575	COG1653	transport
FRC90_RS15580	COG1175	transmembrane transport
FRC90_RS15585	COG0395	ABC-type sugar transport system, permease component
FRC90_RS15590	COG3842	ATPase activity
FRC90_RS15600	COG0584	glycerophosphoryl diester phosphodiesterase
FRC90_RS15605	COG3264	Mechanosensitive ion channel
FRC90_RS15605	COG1511	domain protein
FRC90_RS15635	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FRC90_RS15640	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FRC90_RS15650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FRC90_RS15655	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC90_RS15660	COG1253	flavin adenine dinucleotide binding
FRC90_RS15670	COG0442	prolyl-tRNA aminoacylation
FRC90_RS15675	COG0494	nUDIX hydrolase
FRC90_RS15680	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FRC90_RS15685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FRC90_RS15690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FRC90_RS15695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FRC90_RS15700	COG0142	geranyltranstransferase activity
FRC90_RS15710	COG1473	amidohydrolase
FRC90_RS15720	COG0583	DNA-binding transcription factor activity
FRC90_RS15740	COG0237	dephospho-CoA kinase activity
FRC90_RS15745	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FRC90_RS15750	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FRC90_RS15755	COG0494	nUDIX hydrolase
FRC90_RS15765	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FRC90_RS15770	COG0653	protein targeting
FRC90_RS15775	COG0739	heme binding
FRC90_RS15790	COG2969	positive regulation of protein catabolic process
FRC90_RS15795	COG0625	glutathione transferase activity
FRC90_RS15800	COG2857	Cytochrome c1
FRC90_RS15805	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FRC90_RS15810	COG0723	plastoquinol--plastocyanin reductase activity
FRC90_RS15815	COG1970	mechanosensitive ion channel activity
FRC90_RS15820	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FRC90_RS15825	COG1136	(ABC) transporter
FRC90_RS15830	COG4591	ABC-type transport system involved in lipoprotein release permease component
FRC90_RS15840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FRC90_RS15855	COG0738	Major facilitator superfamily
FRC90_RS15860	COG0613	PHP domain protein
FRC90_RS15865	COG0009	L-threonylcarbamoyladenylate synthase
FRC90_RS15875	COG1994	Peptidase M50
FRC90_RS15880	COG0180	Tryptophanyl-tRNA synthetase
FRC90_RS15885	COG3209	COG3209 Rhs family protein
FRC90_RS15945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FRC90_RS15990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC90_RS16000	COG4774	siderophore transport
FRC90_RS16005	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC90_RS16060	COG0443	Heat shock 70 kDa protein
FRC90_RS16110	COG0038	chloride channel
FRC90_RS16145	COG3209	COG3209 Rhs family protein
FRC90_RS16155	COG0612	Peptidase, M16
FRC90_RS16160	COG0765	amino acid transport
FRC90_RS16165	COG0765	amino acid transport
FRC90_RS16170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS16185	COG0129	dihydroxy-acid dehydratase activity
FRC90_RS16225	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FRC90_RS16230	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_RS16235	COG0517	IMP dehydrogenase activity
FRC90_RS16235	COG0617	tRNA 3'-terminal CCA addition
FRC90_RS16235	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FRC90_RS16240	COG1253	flavin adenine dinucleotide binding
FRC90_RS16245	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FRC90_RS16250	COG1047	Peptidyl-prolyl cis-trans
FRC90_RS16255	COG2003	Belongs to the UPF0758 family
FRC90_RS16275	COG1193	negative regulation of DNA recombination
FRC90_RS16300	COG0737	Belongs to the 5'-nucleotidase family
FRC90_RS16380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC90_RS16395	COG0534	Mate efflux family protein
FRC90_RS16400	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS16430	COG2771	luxR family
FRC90_RS16435	COG3916	Acyl-homoserine-lactone synthase
FRC90_RS16445	COG1802	Transcriptional regulator
FRC90_RS16455	COG0154	amidase activity
FRC90_RS16500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FRC90_RS16510	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FRC90_RS16515	COG0243	molybdopterin cofactor binding
FRC90_RS16520	COG0840	transmembrane signaling receptor activity
FRC90_RS16525	COG2223	nitrite transmembrane transporter activity
FRC90_RS16530	COG0489	protein tyrosine kinase activity
FRC90_RS16545	COG0028	Belongs to the TPP enzyme family
FRC90_RS16550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_RS16550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC90_RS16580	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FRC90_RS16590	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FRC90_RS16595	COG0156	8-amino-7-oxononanoate synthase activity
FRC90_RS16600	COG0602	queuosine metabolic process
FRC90_RS16605	COG0720	synthase
FRC90_RS16630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FRC90_RS16640	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FRC90_RS16645	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FRC90_RS16650	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FRC90_RS16655	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FRC90_RS16665	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FRC90_RS16670	COG0588	phosphoglycerate mutase activity
FRC90_RS16675	COG0793	Belongs to the peptidase S41A family
FRC90_RS16680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FRC90_RS16690	COG2197	response regulator
FRC90_RS16700	COG5487	UPF0391 membrane protein
FRC90_RS16725	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FRC90_RS16730	COG0742	ribosomal rna small subunit methyltransferase
FRC90_RS16735	COG0612	Peptidase, M16
FRC90_RS16740	COG0612	Peptidase, M16
FRC90_RS16750	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC90_RS16775	COG0840	transmembrane signaling receptor activity
FRC90_RS16780	COG4977	sequence-specific DNA binding
FRC90_RS16795	COG0534	Mate efflux family protein
FRC90_RS16825	COG3842	ATPase activity
FRC90_RS16835	COG0583	DNA-binding transcription factor activity
FRC90_RS16845	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC90_RS16865	COG1999	signal sequence binding
FRC90_RS16870	COG0109	protoheme IX farnesyltransferase activity
FRC90_RS16875	COG1612	heme a metabolic process
FRC90_RS16925	COG2226	methyltransferase
FRC90_RS16930	COG1040	competence protein
FRC90_RS16935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FRC90_RS16940	COG0583	DNA-binding transcription factor activity
FRC90_RS16955	COG1192	Involved in chromosome partitioning
FRC90_RS16960	COG1280	lysine exporter protein (LysE YggA)
FRC90_RS16970	COG4774	siderophore transport
FRC90_RS16990	COG3038	cytochrome b561
FRC90_RS16995	COG1846	Transcriptional regulator
FRC90_RS17000	COG0840	transmembrane signaling receptor activity
FRC90_RS17005	COG0477	Major facilitator Superfamily
FRC90_RS17010	COG2010	Cytochrome c
FRC90_RS17010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS17015	COG2080	2 iron, 2 sulfur cluster binding
FRC90_RS17025	COG3473	Maleate cis-trans isomerase
FRC90_RS17030	COG0596	Alpha beta hydrolase
FRC90_RS17035	COG2309	aminopeptidase activity
FRC90_RS17040	COG1335	isochorismatase
FRC90_RS17045	COG2010	Cytochrome c
FRC90_RS17045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS17070	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS17080	COG2031	fatty acid transporter
FRC90_RS17100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_RS17105	COG0183	Belongs to the thiolase family
FRC90_RS17110	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FRC90_RS17120	COG1414	Transcriptional regulator
FRC90_RS17150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC90_RS17220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC90_RS17235	COG0346	lactoylglutathione lyase activity
FRC90_RS17265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC90_RS17295	COG1132	(ABC) transporter
FRC90_RS17300	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_RS17300	COG0189	ligase activity
FRC90_RS17305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC90_RS17305	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC90_RS17310	COG3045	CreA protein
FRC90_RS17325	COG3145	DNA-N1-methyladenine dioxygenase activity
FRC90_RS17340	COG0753	catalase activity
FRC90_RS17345	COG0745	RESPONSE REGULATOR receiver
FRC90_RS17350	COG0784	Response regulator, receiver
FRC90_RS17350	COG5002	protein histidine kinase activity
FRC90_RS17360	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC90_RS17395	COG0601	transmembrane transport
FRC90_RS17400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC90_RS17410	COG0514	ATP-dependent DNA helicase (RecQ)
FRC90_RS17435	COG3209	COG3209 Rhs family protein
FRC90_RS17435	COG3209	COG3209 Rhs family protein
FRC90_RS17455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC90_RS17460	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC90_RS17465	COG2080	2 iron, 2 sulfur cluster binding
FRC90_RS17505	COG0737	Belongs to the 5'-nucleotidase family
FRC90_RS17510	COG0583	DNA-binding transcription factor activity
FRC90_RS17515	COG2855	membrane
FRC90_RS17525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC90_RS17550	COG2267	carboxylic ester hydrolase activity
FRC90_RS17560	COG3002	Belongs to the UPF0753 family
FRC90_RS17565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC90_RS17610	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FRC90_RS17635	COG0583	DNA-binding transcription factor activity
FRC90_RS17640	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FRC90_RS17650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FRC90_RS17655	COG2814	Major facilitator Superfamily
FRC90_RS17660	COG0316	Belongs to the HesB IscA family
FRC90_RS17675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FRC90_RS17680	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FRC90_RS17685	COG0515	serine threonine protein kinase
FRC90_RS17685	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC90_RS17690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FRC90_RS17695	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FRC90_RS17715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC90_RS17735	COG2076	Multidrug Resistance protein
FRC90_RS17765	COG1126	abc transporter atp-binding protein
FRC90_RS17770	COG0765	amino acid transport
FRC90_RS17775	COG0765	amino acid transport
FRC90_RS17780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS17790	COG0583	DNA-binding transcription factor activity
FRC90_RS17795	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_RS17800	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC90_RS17800	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC90_RS17805	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC90_RS17810	COG5265	(ABC) transporter
FRC90_RS17825	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS17830	COG1024	Enoyl-CoA hydratase
FRC90_RS17840	COG0183	Belongs to the thiolase family
FRC90_RS17850	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_RS17850	COG1024	Enoyl-CoA hydratase
FRC90_RS17860	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS18115	COG1309	transcriptional regulator
FRC90_RS18125	COG0745	RESPONSE REGULATOR receiver
FRC90_RS18130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC90_RS18170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_RS18185	COG1450	Type ii and iii secretion system protein
FRC90_RS18215	COG2165	general secretion pathway protein
FRC90_RS18220	COG4970	Tfp pilus assembly protein FimT
FRC90_RS18225	COG2165	general secretion pathway protein
FRC90_RS18230	COG1459	type II secretion system
FRC90_RS18235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC90_RS18275	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FRC90_RS18280	COG1652	LysM domain
FRC90_RS18300	COG0204	Acyl-transferase
FRC90_RS18305	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FRC90_RS18315	COG0751	glycine-tRNA ligase activity
FRC90_RS18320	COG0752	glycyl-tRNA synthetase alpha subunit
FRC90_RS18325	COG3258	Cytochrome c
FRC90_RS18335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC90_RS18350	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FRC90_RS18355	COG4535	Mg2 and Co2 transporter CorC
FRC90_RS18370	COG1522	sequence-specific DNA binding
FRC90_RS18375	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FRC90_RS18395	COG3186	Phenylalanine-4-hydroxylase
FRC90_RS18410	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS18420	COG1129	ABC transporter
FRC90_RS18425	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC90_RS18435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC90_RS18440	COG1869	D-ribose catabolic process
FRC90_RS18450	COG1196	nuclear chromosome segregation
FRC90_RS18450	COG0741	lytic transglycosylase activity
FRC90_RS18450	COG0739	heme binding
FRC90_RS18455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FRC90_RS18480	COG0617	tRNA 3'-terminal CCA addition
FRC90_RS18495	COG3387	PFAM Glycoside hydrolase 15-related
FRC90_RS18500	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC90_RS18520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC90_RS18535	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS18545	COG2879	small protein
FRC90_RS18550	COG1966	Carbon starvation protein
FRC90_RS18555	COG2197	response regulator
FRC90_RS18565	COG0037	tRNA processing
FRC90_RS18595	COG2255	four-way junction helicase activity
FRC90_RS18605	COG0632	four-way junction helicase activity
FRC90_RS18610	COG1702	phosphate starvation-inducible protein PhoH
FRC90_RS18630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FRC90_RS18635	COG1490	D-aminoacyl-tRNA deacylase activity
FRC90_RS18640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FRC90_RS18645	COG0513	Belongs to the DEAD box helicase family
FRC90_RS18650	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FRC90_RS18655	COG3706	GGDEF domain
FRC90_RS18670	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC90_RS18670	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC90_RS18680	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC90_RS18680	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC90_RS18700	COG0443	Heat shock 70 kDa protein
FRC90_RS18710	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FRC90_RS18715	COG1131	(ABC) transporter
FRC90_RS18720	COG0842	Transport permease protein
FRC90_RS18725	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_RS18735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_RS18755	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC90_RS18760	COG3971	2-oxopent-4-enoate hydratase activity
FRC90_RS18770	COG1846	Transcriptional regulator
FRC90_RS18775	COG1764	response to oxidative stress
FRC90_RS18790	COG0515	serine threonine protein kinase
FRC90_RS18790	COG2815	serine threonine protein kinase
FRC90_RS18865	COG0326	Molecular chaperone. Has ATPase activity
FRC90_RS18880	COG1187	pseudouridine synthase activity
FRC90_RS18895	COG0840	transmembrane signaling receptor activity
FRC90_RS18915	COG3568	Endonuclease Exonuclease Phosphatase
FRC90_RS18920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC90_RS18925	COG0392	lysyltransferase activity
FRC90_RS18930	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FRC90_RS18940	COG0840	transmembrane signaling receptor activity
FRC90_RS18975	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS18980	COG1024	Enoyl-CoA hydratase
FRC90_RS18985	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS18990	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS18995	COG1024	Enoyl-CoA hydratase
FRC90_RS18995	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC90_RS19000	COG0583	DNA-binding transcription factor activity
FRC90_RS19005	COG0501	Belongs to the peptidase M48B family
FRC90_RS19020	COG0418	dihydroorotase activity
FRC90_RS19025	COG2205	protein histidine kinase activity
FRC90_RS19030	COG0745	RESPONSE REGULATOR receiver
FRC90_RS19045	COG1136	(ABC) transporter
FRC90_RS19045	COG0577	efflux transmembrane transporter activity
FRC90_RS19075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC90_RS19135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FRC90_RS19150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FRC90_RS19185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC90_RS19200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FRC90_RS19205	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC90_RS19210	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS19230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FRC90_RS19235	COG0784	Response regulator, receiver
FRC90_RS19235	COG2198	Histidine kinase
FRC90_RS19235	COG2205	protein histidine kinase activity
FRC90_RS19240	COG3012	SEC-C Motif Domain Protein
FRC90_RS19255	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS19270	COG0183	Belongs to the thiolase family
FRC90_RS19275	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FRC90_RS19280	COG0288	reversible hydration of carbon dioxide
FRC90_RS19285	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS19295	COG0789	Transcriptional regulator
FRC90_RS19325	COG0488	(ABC) transporter
FRC90_RS19330	COG2201	protein-glutamate methylesterase activity
FRC90_RS19335	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FRC90_RS19340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC90_RS19345	COG0835	chemotaxis
FRC90_RS19350	COG2198	Histidine kinase
FRC90_RS19350	COG0643	Histidine kinase
FRC90_RS19355	COG0745	RESPONSE REGULATOR receiver
FRC90_RS19365	COG3851	Histidine kinase
FRC90_RS19370	COG2197	response regulator
FRC90_RS19380	COG1987	bacterial-type flagellum assembly
FRC90_RS19395	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FRC90_RS19405	COG1580	Controls the rotational direction of flagella during chemotaxis
FRC90_RS19435	COG1766	The M ring may be actively involved in energy transduction
FRC90_RS19440	COG1677	Flagellar hook-basal body complex protein FliE
FRC90_RS19475	COG4106	trans-aconitate 2-methyltransferase activity
FRC90_RS19485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS19490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC90_RS19495	COG0438	transferase activity, transferring glycosyl groups
FRC90_RS19495	COG1216	Glycosyl transferase, family 2
FRC90_RS19500	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FRC90_RS19505	COG1360	Flagellar Motor Protein
FRC90_RS19510	COG0745	RESPONSE REGULATOR receiver
FRC90_RS19515	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FRC90_RS19520	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC90_RS19560	COG1815	bacterial-type flagellum-dependent cell motility
FRC90_RS19565	COG1558	bacterial-type flagellum-dependent cell motility
FRC90_RS19570	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FRC90_RS19580	COG4787	bacterial-type flagellum-dependent cell motility
FRC90_RS19590	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FRC90_RS19600	COG1706	bacterial-type flagellum-dependent cell motility
FRC90_RS19605	COG1705	Flagellar rod assembly protein muramidase FlgJ
FRC90_RS19605	COG3951	Flagellar rod assembly protein muramidase FlgJ
FRC90_RS19615	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FRC90_RS19630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_RS19640	COG0697	spore germination
FRC90_RS19645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC90_RS19650	COG0625	glutathione transferase activity
FRC90_RS19655	COG0384	phenazine biosynthesis protein PhzF
FRC90_RS19685	COG0840	transmembrane signaling receptor activity
FRC90_RS19730	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC90_RS19765	COG0861	Integral membrane protein TerC family
FRC90_RS19770	COG0583	DNA-binding transcription factor activity
FRC90_RS19795	COG3119	arylsulfatase activity
FRC90_RS19810	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FRC90_RS19820	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FRC90_RS19840	COG0210	DNA helicase
FRC90_RS19860	COG0343	queuine tRNA-ribosyltransferase activity
FRC90_RS19890	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS19915	COG1522	sequence-specific DNA binding
FRC90_RS19920	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FRC90_RS19930	COG0840	transmembrane signaling receptor activity
FRC90_RS19970	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS19975	COG2072	flavoprotein involved in K transport
FRC90_RS19985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS20005	COG2365	Tyrosine phosphatase family
FRC90_RS20010	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS20020	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS20025	COG1116	anion transmembrane transporter activity
FRC90_RS20040	COG3046	protein related to deoxyribodipyrimidine photolyase
FRC90_RS20050	COG3550	peptidyl-serine autophosphorylation
FRC90_RS20065	COG2032	superoxide dismutase activity
FRC90_RS20080	COG2204	response regulator
FRC90_RS20085	COG5000	phosphorelay sensor kinase activity
FRC90_RS20095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC90_RS20095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC90_RS20105	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FRC90_RS20110	COG0085	RNA polymerase activity
FRC90_RS20115	COG0222	ribosome binding
FRC90_RS20120	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FRC90_RS20125	COG0081	regulation of translation
FRC90_RS20130	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FRC90_RS20140	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FRC90_RS20150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC90_RS20195	COG0189	ligase activity
FRC90_RS20200	COG3135	benzoate transporter
FRC90_RS20205	COG3158	transport of potassium into the cell
FRC90_RS20215	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FRC90_RS20220	COG0569	domain protein
FRC90_RS20225	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FRC90_RS20245	COG0495	leucyl-tRNA aminoacylation
FRC90_RS20255	COG3300	MHYT domain
FRC90_RS20255	COG5001	Diguanylate cyclase
FRC90_RS20270	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FRC90_RS20275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC90_RS20280	COG0735	belongs to the Fur family
FRC90_RS20285	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FRC90_RS20295	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FRC90_RS20300	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FRC90_RS20310	COG3118	belongs to the thioredoxin family
FRC90_RS20315	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FRC90_RS20320	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FRC90_RS20325	COG0009	L-threonylcarbamoyladenylate synthase
FRC90_RS20350	COG1214	PFAM Peptidase M22, glycoprotease
FRC90_RS20365	COG0598	Magnesium transport protein CorA
FRC90_RS20375	COG0318	PFAM AMP-dependent synthetase and ligase
FRC90_RS20410	COG0469	pyruvate kinase activity
FRC90_RS20415	COG0006	proline dipeptidase activity
FRC90_RS20420	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FRC90_RS20425	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FRC90_RS20430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FRC90_RS20450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FRC90_RS20460	COG0583	DNA-binding transcription factor activity
FRC90_RS20495	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC90_RS20550	COG0668	transmembrane transport
FRC90_RS20560	COG2194	sulfuric ester hydrolase activity
FRC90_RS20565	COG1028	Short-chain dehydrogenase reductase Sdr
FRC90_RS20580	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FRC90_RS20635	COG1714	RDD family
FRC90_RS20675	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FRC90_RS20675	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FRC90_RS20705	COG0583	DNA-binding transcription factor activity
FRC90_RS20715	COG0642	Histidine kinase
FRC90_RS20730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FRC90_RS20735	COG2137	regulation of response to DNA damage stimulus
FRC90_RS20745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC90_RS20750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC90_RS20755	COG1862	Preprotein translocase
FRC90_RS20765	COG1522	sequence-specific DNA binding
FRC90_RS20775	COG2814	Major facilitator Superfamily
FRC90_RS20795	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FRC90_RS20825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FRC90_RS20830	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC90_RS20845	COG1309	transcriptional regulator
FRC90_RS20855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC90_RS20880	COG0625	glutathione transferase activity
FRC90_RS20905	COG0861	Integral membrane protein TerC family
FRC90_RS20915	COG1950	PFAM Membrane protein of
FRC90_RS20920	COG4783	chaperone-mediated protein folding
FRC90_RS20925	COG0315	cyclic pyranopterin monophosphate synthase activity
FRC90_RS20935	COG3307	-O-antigen
FRC90_RS20945	COG1716	ATPase activity
FRC90_RS20950	COG0631	protein serine/threonine phosphatase activity
FRC90_RS20955	COG0861	Integral membrane protein TerC family
FRC90_RS20960	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FRC90_RS20965	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC90_RS20970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FRC90_RS20975	COG0758	DNA mediated transformation
FRC90_RS20985	COG0242	peptide deformylase activity
FRC90_RS20995	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FRC90_RS21010	COG0126	phosphoglycerate kinase activity
FRC90_RS21020	COG0697	spore germination
FRC90_RS21025	COG0284	orotidine-5'-phosphate decarboxylase activity
FRC90_RS21030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC90_RS21060	COG0840	transmembrane signaling receptor activity
FRC90_RS21090	COG0529	Catalyzes the synthesis of activated sulfate
FRC90_RS21100	COG2814	Major facilitator Superfamily
FRC90_RS21110	COG0629	single-stranded DNA binding
FRC90_RS21135	COG0640	Transcriptional regulator
FRC90_RS21160	COG1620	l-lactate permease
FRC90_RS21165	COG0482	sulfurtransferase activity
FRC90_RS21170	COG0494	nUDIX hydrolase
FRC90_RS21200	COG0307	riboflavin synthase, alpha
FRC90_RS21225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC90_RS21230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC90_RS21290	COG1802	Transcriptional regulator
FRC90_RS21345	COG0281	malic enzyme
FRC90_RS21345	COG0280	phosphate acetyltransferase
FRC90_RS21360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FRC90_RS21365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC90_RS21370	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FRC90_RS21380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FRC90_RS21395	COG1196	nuclear chromosome segregation
FRC90_RS21400	COG2814	Major facilitator Superfamily
FRC90_RS21410	COG2207	Transcriptional regulator
FRC90_RS21415	COG1113	amino acid transport
FRC90_RS21420	COG4303	Ethanolamine ammonia lyase large subunit
FRC90_RS21425	COG4302	ethanolamine ammonia-lyase activity
FRC90_RS21435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC90_RS21440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC90_RS21445	COG2119	membrane
FRC90_RS21450	COG0724	RNA recognition motif
FRC90_RS21455	COG0724	RNA recognition motif
FRC90_RS21460	COG0300	oxidoreductase activity
FRC90_RS21470	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FRC90_RS21485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FRC90_RS21505	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FRC90_RS21515	COG0706	membrane insertase activity
FRC90_RS21520	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FRC90_RS21525	COG0594	ribonuclease P activity
FRC90_RS21530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FRC90_RS21535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC90_RS21575	COG1764	response to oxidative stress
FRC90_RS21595	COG1199	ATP-dependent helicase activity
FRC90_RS21610	COG2176	DNA-directed DNA polymerase activity
FRC90_RS21625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC90_RS21630	COG0791	NLP P60 protein
FRC90_RS21635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC90_RS21655	COG2974	May be involved in recombination
FRC90_RS21660	COG2715	membrane protein required for spore maturation
FRC90_RS21685	COG0183	Belongs to the thiolase family
FRC90_RS21690	COG0789	Transcriptional regulator
FRC90_RS21700	COG2217	Heavy metal translocating P-type atpase
FRC90_RS21735	COG0745	RESPONSE REGULATOR receiver
FRC90_RS21740	COG0642	Histidine kinase
FRC90_RS21760	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FRC90_RS21765	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC90_RS21785	COG0445	tRNA wobble uridine modification
FRC90_RS21790	COG0357	Ribosomal RNA small subunit methyltransferase G
FRC90_RS21795	COG1280	lysine exporter protein (LysE YggA)
FRC90_RS21800	COG1192	Involved in chromosome partitioning
FRC90_RS21825	COG0493	'glutamate synthase
FRC90_RS21845	COG0277	FAD linked oxidase domain protein
FRC90_RS21850	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC90_RS21850	COG0546	phosphoglycolate phosphatase activity
FRC90_RS21865	COG2272	Belongs to the type-B carboxylesterase lipase family
FRC90_RS21885	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FRC90_RS21920	COG3411	Ferredoxin
FRC90_RS21935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_RS22025	COG0277	FAD linked oxidase domain protein
FRC90_RS22040	COG2096	Adenosyltransferase
FRC90_RS22045	COG2050	protein possibly involved in aromatic compounds catabolism
FRC90_RS22060	COG2233	PERMEase
FRC90_RS22080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FRC90_RS22095	COG0583	DNA-binding transcription factor activity
FRC90_RS22110	COG1116	anion transmembrane transporter activity
FRC90_RS22115	COG0395	ABC-type sugar transport system, permease component
FRC90_RS22135	COG1414	Transcriptional regulator
FRC90_RS22140	COG0501	Belongs to the peptidase M48B family
FRC90_RS22150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC90_RS22165	COG2423	ornithine cyclodeaminase activity
FRC90_RS22175	COG1183	phosphatidylcholine synthase activity
FRC90_RS22185	COG0850	regulation of cytokinetic process
FRC90_RS22190	COG2894	cell division
FRC90_RS22195	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FRC90_RS22200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC90_RS22215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC90_RS22220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC90_RS22230	COG1309	transcriptional regulator
FRC90_RS22255	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FRC90_RS22260	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FRC90_RS22270	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FRC90_RS22275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC90_RS22285	COG1960	acyl-CoA dehydrogenase activity
FRC90_RS22305	COG0625	glutathione transferase activity
FRC90_RS22310	COG2271	Major facilitator Superfamily
FRC90_RS22320	COG2423	ornithine cyclodeaminase activity
FRC90_RS22350	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FRC90_RS22405	COG0840	transmembrane signaling receptor activity
FRC90_RS22440	COG0583	DNA-binding transcription factor activity
FRC90_RS22455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC90_RS22460	COG3181	Tripartite tricarboxylate transporter family receptor
FRC90_RS22500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FRC90_RS22510	COG2326	polyphosphate kinase activity
FRC90_RS22550	COG0583	DNA-binding transcription factor activity