locus-tag	class	description
FRC97_RS00005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC97_RS00070	COG3736	Type IV secretory pathway, component VirB8
FRC97_RS00075	COG3504	Conjugal transfer protein
FRC97_RS00090	COG3505	Type IV secretory pathway VirD4
FRC97_RS00095	COG2885	chlorophyll binding
FRC97_RS00255	COG1475	DNA binding
FRC97_RS00310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FRC97_RS00320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FRC97_RS00325	COG0243	molybdopterin cofactor binding
FRC97_RS00330	COG0840	transmembrane signaling receptor activity
FRC97_RS00335	COG2223	nitrite transmembrane transporter activity
FRC97_RS00340	COG0489	protein tyrosine kinase activity
FRC97_RS00355	COG0028	Belongs to the TPP enzyme family
FRC97_RS00360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_RS00360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_RS00390	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FRC97_RS00400	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FRC97_RS00405	COG0156	8-amino-7-oxononanoate synthase activity
FRC97_RS00410	COG0602	queuosine metabolic process
FRC97_RS00415	COG0720	synthase
FRC97_RS00440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FRC97_RS00450	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FRC97_RS00455	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FRC97_RS00460	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FRC97_RS00465	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FRC97_RS00475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FRC97_RS00480	COG0588	phosphoglycerate mutase activity
FRC97_RS00485	COG0793	Belongs to the peptidase S41A family
FRC97_RS00490	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FRC97_RS00500	COG2197	response regulator
FRC97_RS00510	COG5487	UPF0391 membrane protein
FRC97_RS00535	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FRC97_RS00540	COG0742	ribosomal rna small subunit methyltransferase
FRC97_RS00545	COG0612	Peptidase, M16
FRC97_RS00550	COG0612	Peptidase, M16
FRC97_RS00560	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC97_RS00585	COG0840	transmembrane signaling receptor activity
FRC97_RS00590	COG4977	sequence-specific DNA binding
FRC97_RS00605	COG0534	Mate efflux family protein
FRC97_RS00640	COG3842	ATPase activity
FRC97_RS00650	COG0583	DNA-binding transcription factor activity
FRC97_RS00665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC97_RS00685	COG1999	signal sequence binding
FRC97_RS00690	COG0109	protoheme IX farnesyltransferase activity
FRC97_RS00695	COG1612	heme a metabolic process
FRC97_RS00745	COG2226	methyltransferase
FRC97_RS00750	COG1040	competence protein
FRC97_RS00755	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FRC97_RS00760	COG0583	DNA-binding transcription factor activity
FRC97_RS00775	COG1192	Involved in chromosome partitioning
FRC97_RS00780	COG1280	lysine exporter protein (LysE YggA)
FRC97_RS00790	COG4774	siderophore transport
FRC97_RS00810	COG3038	cytochrome b561
FRC97_RS00815	COG1846	Transcriptional regulator
FRC97_RS00820	COG0840	transmembrane signaling receptor activity
FRC97_RS00825	COG0477	Major facilitator Superfamily
FRC97_RS00835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS00835	COG2010	Cytochrome c
FRC97_RS00840	COG2080	2 iron, 2 sulfur cluster binding
FRC97_RS00850	COG3473	Maleate cis-trans isomerase
FRC97_RS00855	COG0596	Alpha beta hydrolase
FRC97_RS00860	COG2309	aminopeptidase activity
FRC97_RS00865	COG1335	isochorismatase
FRC97_RS00870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS00870	COG2010	Cytochrome c
FRC97_RS00895	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS00905	COG2031	fatty acid transporter
FRC97_RS00925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_RS00930	COG0183	Belongs to the thiolase family
FRC97_RS00935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FRC97_RS00945	COG1414	Transcriptional regulator
FRC97_RS00975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC97_RS01045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_RS01060	COG0346	lactoylglutathione lyase activity
FRC97_RS01090	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC97_RS01120	COG1132	(ABC) transporter
FRC97_RS01125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_RS01125	COG0189	ligase activity
FRC97_RS01130	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC97_RS01130	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_RS01135	COG3045	CreA protein
FRC97_RS01150	COG3145	DNA-N1-methyladenine dioxygenase activity
FRC97_RS01165	COG0753	catalase activity
FRC97_RS01170	COG0745	RESPONSE REGULATOR receiver
FRC97_RS01175	COG5002	protein histidine kinase activity
FRC97_RS01175	COG0784	Response regulator, receiver
FRC97_RS01185	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC97_RS01220	COG0601	transmembrane transport
FRC97_RS01225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_RS01235	COG0514	ATP-dependent DNA helicase (RecQ)
FRC97_RS01255	COG3209	COG3209 Rhs family protein
FRC97_RS01255	COG3209	COG3209 Rhs family protein
FRC97_RS01275	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS01280	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC97_RS01285	COG2080	2 iron, 2 sulfur cluster binding
FRC97_RS01325	COG0737	Belongs to the 5'-nucleotidase family
FRC97_RS01330	COG0583	DNA-binding transcription factor activity
FRC97_RS01335	COG2855	membrane
FRC97_RS01345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC97_RS01370	COG2267	carboxylic ester hydrolase activity
FRC97_RS01380	COG3002	Belongs to the UPF0753 family
FRC97_RS01385	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC97_RS01430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FRC97_RS01455	COG0583	DNA-binding transcription factor activity
FRC97_RS01460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FRC97_RS01470	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FRC97_RS01475	COG2814	Major facilitator Superfamily
FRC97_RS01480	COG0316	Belongs to the HesB IscA family
FRC97_RS01495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FRC97_RS01500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FRC97_RS01505	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC97_RS01505	COG0515	serine threonine protein kinase
FRC97_RS01510	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FRC97_RS01515	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FRC97_RS01535	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC97_RS01545	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FRC97_RS01555	COG2076	Multidrug Resistance protein
FRC97_RS01585	COG1126	abc transporter atp-binding protein
FRC97_RS01590	COG0765	amino acid transport
FRC97_RS01595	COG0765	amino acid transport
FRC97_RS01600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS01610	COG0583	DNA-binding transcription factor activity
FRC97_RS01615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_RS01620	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_RS01620	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_RS01625	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS01630	COG5265	(ABC) transporter
FRC97_RS01645	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS01650	COG1024	Enoyl-CoA hydratase
FRC97_RS01660	COG0183	Belongs to the thiolase family
FRC97_RS01680	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS01690	COG1309	transcriptional regulator
FRC97_RS01700	COG0745	RESPONSE REGULATOR receiver
FRC97_RS01705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC97_RS01745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_RS01760	COG1450	Type ii and iii secretion system protein
FRC97_RS01790	COG2165	general secretion pathway protein
FRC97_RS01795	COG4970	Tfp pilus assembly protein FimT
FRC97_RS01800	COG2165	general secretion pathway protein
FRC97_RS01805	COG1459	type II secretion system
FRC97_RS01810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC97_RS01850	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FRC97_RS01855	COG1652	LysM domain
FRC97_RS01875	COG0204	Acyl-transferase
FRC97_RS01880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FRC97_RS01890	COG0751	glycine-tRNA ligase activity
FRC97_RS01895	COG0752	glycyl-tRNA synthetase alpha subunit
FRC97_RS01900	COG3258	Cytochrome c
FRC97_RS01910	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC97_RS01925	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FRC97_RS01930	COG4535	Mg2 and Co2 transporter CorC
FRC97_RS01945	COG1522	sequence-specific DNA binding
FRC97_RS01950	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
FRC97_RS01970	COG3186	Phenylalanine-4-hydroxylase
FRC97_RS01985	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS01995	COG1129	ABC transporter
FRC97_RS02000	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS02010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC97_RS02015	COG1869	D-ribose catabolic process
FRC97_RS02025	COG0741	lytic transglycosylase activity
FRC97_RS02025	COG0739	heme binding
FRC97_RS02025	COG1196	nuclear chromosome segregation
FRC97_RS02030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FRC97_RS02055	COG0617	tRNA 3'-terminal CCA addition
FRC97_RS02070	COG3387	PFAM Glycoside hydrolase 15-related
FRC97_RS02075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FRC97_RS02095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS02110	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS02120	COG2879	small protein
FRC97_RS02125	COG1966	Carbon starvation protein
FRC97_RS02130	COG2197	response regulator
FRC97_RS02140	COG0037	tRNA processing
FRC97_RS02170	COG2255	four-way junction helicase activity
FRC97_RS02185	COG0632	four-way junction helicase activity
FRC97_RS02190	COG1702	phosphate starvation-inducible protein PhoH
FRC97_RS02210	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FRC97_RS02215	COG1490	D-aminoacyl-tRNA deacylase activity
FRC97_RS02220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FRC97_RS02225	COG0513	Belongs to the DEAD box helicase family
FRC97_RS02230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FRC97_RS02235	COG3706	GGDEF domain
FRC97_RS02250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC97_RS02250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FRC97_RS02260	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC97_RS02260	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC97_RS02280	COG0443	Heat shock 70 kDa protein
FRC97_RS02290	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FRC97_RS02295	COG1131	(ABC) transporter
FRC97_RS02300	COG0842	Transport permease protein
FRC97_RS02305	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_RS02315	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_RS02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
FRC97_RS02340	COG3971	2-oxopent-4-enoate hydratase activity
FRC97_RS02350	COG1846	Transcriptional regulator
FRC97_RS02355	COG1764	response to oxidative stress
FRC97_RS02370	COG0515	serine threonine protein kinase
FRC97_RS02370	COG2815	serine threonine protein kinase
FRC97_RS02415	COG3209	COG3209 Rhs family protein
FRC97_RS02460	COG0326	Molecular chaperone. Has ATPase activity
FRC97_RS02490	COG0840	transmembrane signaling receptor activity
FRC97_RS02510	COG3568	Endonuclease Exonuclease Phosphatase
FRC97_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_RS02520	COG0392	lysyltransferase activity
FRC97_RS02525	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
FRC97_RS02535	COG0840	transmembrane signaling receptor activity
FRC97_RS02570	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS02575	COG1024	Enoyl-CoA hydratase
FRC97_RS02580	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS02585	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS02590	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_RS02590	COG1024	Enoyl-CoA hydratase
FRC97_RS02595	COG0583	DNA-binding transcription factor activity
FRC97_RS02600	COG0501	Belongs to the peptidase M48B family
FRC97_RS02615	COG0418	dihydroorotase activity
FRC97_RS02620	COG2205	protein histidine kinase activity
FRC97_RS02625	COG0745	RESPONSE REGULATOR receiver
FRC97_RS02640	COG0577	efflux transmembrane transporter activity
FRC97_RS02640	COG1136	(ABC) transporter
FRC97_RS02670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC97_RS02720	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FRC97_RS02735	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FRC97_RS02770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_RS02785	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FRC97_RS02790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC97_RS02795	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS02815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FRC97_RS02820	COG2198	Histidine kinase
FRC97_RS02820	COG2205	protein histidine kinase activity
FRC97_RS02820	COG0784	Response regulator, receiver
FRC97_RS02825	COG3012	SEC-C Motif Domain Protein
FRC97_RS02840	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS02855	COG0183	Belongs to the thiolase family
FRC97_RS02860	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FRC97_RS02865	COG0288	reversible hydration of carbon dioxide
FRC97_RS02870	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS02880	COG0789	Transcriptional regulator
FRC97_RS02910	COG0488	(ABC) transporter
FRC97_RS02915	COG2201	protein-glutamate methylesterase activity
FRC97_RS02920	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FRC97_RS02925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FRC97_RS02930	COG0835	chemotaxis
FRC97_RS02935	COG2198	Histidine kinase
FRC97_RS02935	COG0643	Histidine kinase
FRC97_RS02940	COG0745	RESPONSE REGULATOR receiver
FRC97_RS02950	COG3851	Histidine kinase
FRC97_RS02955	COG2197	response regulator
FRC97_RS02965	COG1987	bacterial-type flagellum assembly
FRC97_RS02980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FRC97_RS02990	COG1580	Controls the rotational direction of flagella during chemotaxis
FRC97_RS03020	COG1766	The M ring may be actively involved in energy transduction
FRC97_RS03025	COG1677	Flagellar hook-basal body complex protein FliE
FRC97_RS03060	COG4106	trans-aconitate 2-methyltransferase activity
FRC97_RS03070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS03075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FRC97_RS03080	COG0438	transferase activity, transferring glycosyl groups
FRC97_RS03080	COG1216	Glycosyl transferase, family 2
FRC97_RS03085	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FRC97_RS03090	COG1360	Flagellar Motor Protein
FRC97_RS03095	COG0745	RESPONSE REGULATOR receiver
FRC97_RS03100	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FRC97_RS03105	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC97_RS03145	COG1815	bacterial-type flagellum-dependent cell motility
FRC97_RS03150	COG1558	bacterial-type flagellum-dependent cell motility
FRC97_RS03155	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FRC97_RS03165	COG4787	bacterial-type flagellum-dependent cell motility
FRC97_RS03175	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FRC97_RS03185	COG1706	bacterial-type flagellum-dependent cell motility
FRC97_RS03190	COG3951	Flagellar rod assembly protein muramidase FlgJ
FRC97_RS03190	COG1705	Flagellar rod assembly protein muramidase FlgJ
FRC97_RS03200	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FRC97_RS03215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_RS03225	COG0697	spore germination
FRC97_RS03230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_RS03235	COG0625	glutathione transferase activity
FRC97_RS03240	COG0384	phenazine biosynthesis protein PhzF
FRC97_RS03270	COG0840	transmembrane signaling receptor activity
FRC97_RS03315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC97_RS03350	COG0861	Integral membrane protein TerC family
FRC97_RS03355	COG0583	DNA-binding transcription factor activity
FRC97_RS03380	COG3119	arylsulfatase activity
FRC97_RS03395	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FRC97_RS03405	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FRC97_RS03425	COG0210	DNA helicase
FRC97_RS03445	COG0343	queuine tRNA-ribosyltransferase activity
FRC97_RS03480	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS03505	COG1522	sequence-specific DNA binding
FRC97_RS03510	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FRC97_RS03520	COG0840	transmembrane signaling receptor activity
FRC97_RS03560	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS03565	COG2072	flavoprotein involved in K transport
FRC97_RS03575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS03595	COG2365	Tyrosine phosphatase family
FRC97_RS03600	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS03610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS03615	COG1116	anion transmembrane transporter activity
FRC97_RS03630	COG3046	protein related to deoxyribodipyrimidine photolyase
FRC97_RS03655	COG2032	superoxide dismutase activity
FRC97_RS03670	COG2204	response regulator
FRC97_RS03675	COG5000	phosphorelay sensor kinase activity
FRC97_RS03685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC97_RS03685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_RS03695	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FRC97_RS03700	COG0085	RNA polymerase activity
FRC97_RS03705	COG0222	ribosome binding
FRC97_RS03710	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FRC97_RS03715	COG0081	regulation of translation
FRC97_RS03720	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FRC97_RS03730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FRC97_RS03740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC97_RS03785	COG0189	ligase activity
FRC97_RS03790	COG3135	benzoate transporter
FRC97_RS03795	COG3158	transport of potassium into the cell
FRC97_RS03810	COG0569	domain protein
FRC97_RS03815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FRC97_RS03835	COG0495	leucyl-tRNA aminoacylation
FRC97_RS03845	COG3300	MHYT domain
FRC97_RS03845	COG5001	Diguanylate cyclase
FRC97_RS03860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FRC97_RS03865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRC97_RS03870	COG0735	belongs to the Fur family
FRC97_RS03875	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FRC97_RS03885	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FRC97_RS03895	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FRC97_RS03905	COG3118	belongs to the thioredoxin family
FRC97_RS03910	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FRC97_RS03915	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FRC97_RS03920	COG0009	L-threonylcarbamoyladenylate synthase
FRC97_RS03945	COG1214	PFAM Peptidase M22, glycoprotease
FRC97_RS03960	COG0598	Magnesium transport protein CorA
FRC97_RS03970	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS04005	COG0469	pyruvate kinase activity
FRC97_RS04010	COG0006	proline dipeptidase activity
FRC97_RS04015	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FRC97_RS04020	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FRC97_RS04025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FRC97_RS04045	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FRC97_RS04055	COG0583	DNA-binding transcription factor activity
FRC97_RS04090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC97_RS04145	COG0668	transmembrane transport
FRC97_RS04155	COG2194	sulfuric ester hydrolase activity
FRC97_RS04160	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS04175	COG2764	glyoxalase bleomycin resistance protein dioxygenase
FRC97_RS04230	COG1714	RDD family
FRC97_RS04270	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FRC97_RS04270	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FRC97_RS04300	COG0583	DNA-binding transcription factor activity
FRC97_RS04310	COG0642	Histidine kinase
FRC97_RS04325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FRC97_RS04330	COG2137	regulation of response to DNA damage stimulus
FRC97_RS04340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC97_RS04345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FRC97_RS04350	COG1862	Preprotein translocase
FRC97_RS04360	COG1522	sequence-specific DNA binding
FRC97_RS04370	COG2814	Major facilitator Superfamily
FRC97_RS04390	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FRC97_RS04420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FRC97_RS04425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC97_RS04440	COG1309	transcriptional regulator
FRC97_RS04450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_RS04475	COG0625	glutathione transferase activity
FRC97_RS04500	COG0861	Integral membrane protein TerC family
FRC97_RS04510	COG1950	PFAM Membrane protein of
FRC97_RS04515	COG4783	chaperone-mediated protein folding
FRC97_RS04520	COG0315	cyclic pyranopterin monophosphate synthase activity
FRC97_RS04530	COG3307	-O-antigen
FRC97_RS04540	COG1716	ATPase activity
FRC97_RS04545	COG0631	protein serine/threonine phosphatase activity
FRC97_RS04550	COG0861	Integral membrane protein TerC family
FRC97_RS04555	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FRC97_RS04560	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC97_RS04565	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FRC97_RS04570	COG0758	DNA mediated transformation
FRC97_RS04580	COG0242	peptide deformylase activity
FRC97_RS04590	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FRC97_RS04605	COG0126	phosphoglycerate kinase activity
FRC97_RS04615	COG0697	spore germination
FRC97_RS04620	COG0284	orotidine-5'-phosphate decarboxylase activity
FRC97_RS04625	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC97_RS04655	COG0840	transmembrane signaling receptor activity
FRC97_RS04685	COG0529	Catalyzes the synthesis of activated sulfate
FRC97_RS04695	COG2814	Major facilitator Superfamily
FRC97_RS04705	COG0629	single-stranded DNA binding
FRC97_RS04730	COG0640	Transcriptional regulator
FRC97_RS04755	COG1620	l-lactate permease
FRC97_RS04760	COG0482	sulfurtransferase activity
FRC97_RS04765	COG0494	nUDIX hydrolase
FRC97_RS04795	COG0307	riboflavin synthase, alpha
FRC97_RS04820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC97_RS04825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC97_RS04885	COG1802	Transcriptional regulator
FRC97_RS04935	COG0280	phosphate acetyltransferase
FRC97_RS04935	COG0281	malic enzyme
FRC97_RS04950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FRC97_RS04955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_RS04960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FRC97_RS04970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FRC97_RS04985	COG1196	nuclear chromosome segregation
FRC97_RS04990	COG2814	Major facilitator Superfamily
FRC97_RS05000	COG2207	Transcriptional regulator
FRC97_RS05005	COG1113	amino acid transport
FRC97_RS05010	COG4303	Ethanolamine ammonia lyase large subunit
FRC97_RS05015	COG4302	ethanolamine ammonia-lyase activity
FRC97_RS05025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_RS05030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_RS05035	COG2119	membrane
FRC97_RS05040	COG0724	RNA recognition motif
FRC97_RS05045	COG0724	RNA recognition motif
FRC97_RS05050	COG0300	oxidoreductase activity
FRC97_RS05060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FRC97_RS05075	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FRC97_RS05095	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FRC97_RS05105	COG0706	membrane insertase activity
FRC97_RS05110	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FRC97_RS05115	COG0594	ribonuclease P activity
FRC97_RS05120	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FRC97_RS05125	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC97_RS05175	COG1764	response to oxidative stress
FRC97_RS05195	COG1199	ATP-dependent helicase activity
FRC97_RS05210	COG2176	DNA-directed DNA polymerase activity
FRC97_RS05225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_RS05230	COG0791	NLP P60 protein
FRC97_RS05235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC97_RS05255	COG2974	May be involved in recombination
FRC97_RS05260	COG2715	membrane protein required for spore maturation
FRC97_RS05285	COG0183	Belongs to the thiolase family
FRC97_RS05290	COG0789	Transcriptional regulator
FRC97_RS05300	COG2217	Heavy metal translocating P-type atpase
FRC97_RS05335	COG0745	RESPONSE REGULATOR receiver
FRC97_RS05340	COG0642	Histidine kinase
FRC97_RS05360	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FRC97_RS05365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS05385	COG0445	tRNA wobble uridine modification
FRC97_RS05390	COG0357	Ribosomal RNA small subunit methyltransferase G
FRC97_RS05395	COG1280	lysine exporter protein (LysE YggA)
FRC97_RS05400	COG1192	Involved in chromosome partitioning
FRC97_RS05425	COG0493	'glutamate synthase
FRC97_RS05445	COG0277	FAD linked oxidase domain protein
FRC97_RS05450	COG0546	phosphoglycolate phosphatase activity
FRC97_RS05450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC97_RS05465	COG2272	Belongs to the type-B carboxylesterase lipase family
FRC97_RS05485	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FRC97_RS05520	COG3411	Ferredoxin
FRC97_RS05535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_RS05625	COG0277	FAD linked oxidase domain protein
FRC97_RS05640	COG2096	Adenosyltransferase
FRC97_RS05645	COG2050	protein possibly involved in aromatic compounds catabolism
FRC97_RS05660	COG2233	PERMEase
FRC97_RS05680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FRC97_RS05695	COG0583	DNA-binding transcription factor activity
FRC97_RS05710	COG1116	anion transmembrane transporter activity
FRC97_RS05715	COG0395	ABC-type sugar transport system, permease component
FRC97_RS05735	COG1414	Transcriptional regulator
FRC97_RS05740	COG0501	Belongs to the peptidase M48B family
FRC97_RS05750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC97_RS05765	COG2423	ornithine cyclodeaminase activity
FRC97_RS05775	COG1183	phosphatidylcholine synthase activity
FRC97_RS05785	COG0850	regulation of cytokinetic process
FRC97_RS05790	COG2894	cell division
FRC97_RS05795	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FRC97_RS05800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FRC97_RS05815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC97_RS05820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS05830	COG1309	transcriptional regulator
FRC97_RS05855	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
FRC97_RS05860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FRC97_RS05870	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FRC97_RS05875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_RS05885	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS05905	COG0625	glutathione transferase activity
FRC97_RS05910	COG2271	Major facilitator Superfamily
FRC97_RS05920	COG2423	ornithine cyclodeaminase activity
FRC97_RS05950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FRC97_RS06005	COG0840	transmembrane signaling receptor activity
FRC97_RS06040	COG0583	DNA-binding transcription factor activity
FRC97_RS06055	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS06060	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS06100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FRC97_RS06110	COG2326	polyphosphate kinase activity
FRC97_RS06150	COG0583	DNA-binding transcription factor activity
FRC97_RS06180	COG0583	DNA-binding transcription factor activity
FRC97_RS06195	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FRC97_RS06200	COG1126	abc transporter atp-binding protein
FRC97_RS06205	COG0765	amino acid transport
FRC97_RS06210	COG0765	amino acid transport
FRC97_RS06235	COG1410	methionine synthase
FRC97_RS06235	COG0646	methionine synthase
FRC97_RS06290	COG0583	DNA-binding transcription factor activity
FRC97_RS06300	COG0840	transmembrane signaling receptor activity
FRC97_RS06305	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS06310	COG4191	Histidine kinase
FRC97_RS06320	COG0606	chelatase, subunit chli
FRC97_RS06330	COG0347	Belongs to the P(II) protein family
FRC97_RS06335	COG0004	ammonium transporteR
FRC97_RS06380	COG0277	FAD linked oxidase domain protein
FRC97_RS06390	COG0247	lactate metabolic process
FRC97_RS06420	COG0386	Belongs to the glutathione peroxidase family
FRC97_RS06430	COG0477	Major facilitator Superfamily
FRC97_RS06435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FRC97_RS06445	COG0747	negative chemotaxis
FRC97_RS06465	COG0625	glutathione transferase activity
FRC97_RS06470	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FRC97_RS06515	COG1215	transferase activity, transferring glycosyl groups
FRC97_RS06535	COG0477	Major facilitator Superfamily
FRC97_RS06545	COG0745	RESPONSE REGULATOR receiver
FRC97_RS06550	COG2211	Major facilitator Superfamily
FRC97_RS06570	COG0501	Belongs to the peptidase M48B family
FRC97_RS06575	COG0471	metal ion transport
FRC97_RS06580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC97_RS06600	COG0583	DNA-binding transcription factor activity
FRC97_RS06605	COG2814	Major facilitator Superfamily
FRC97_RS06615	COG0708	Exodeoxyribonuclease III
FRC97_RS06620	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FRC97_RS06630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC97_RS06635	COG0154	amidase activity
FRC97_RS06640	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FRC97_RS06645	COG1077	Cell shape determining protein MreB Mrl
FRC97_RS06655	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FRC97_RS06660	COG0768	penicillin binding
FRC97_RS06675	COG0765	amino acid transport
FRC97_RS06680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS06685	COG1760	l-serine dehydratase
FRC97_RS06705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC97_RS06710	COG1127	ABC transporter
FRC97_RS06735	COG3237	CsbD-like
FRC97_RS06755	COG4452	Inner membrane protein CreD
FRC97_RS06760	COG2205	protein histidine kinase activity
FRC97_RS06765	COG0745	RESPONSE REGULATOR receiver
FRC97_RS06770	COG2095	MarC family integral membrane protein
FRC97_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS06780	COG0412	Dienelactone hydrolase
FRC97_RS06790	COG1566	PFAM secretion protein HlyD family protein
FRC97_RS06800	COG1846	Transcriptional regulator
FRC97_RS06805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC97_RS06805	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_RS06810	COG0598	Magnesium transport protein CorA
FRC97_RS06820	COG1981	membrane
FRC97_RS06835	COG2945	thiolester hydrolase activity
FRC97_RS06840	COG1686	Belongs to the peptidase S11 family
FRC97_RS06845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FRC97_RS06850	COG0049	tRNA binding
FRC97_RS06855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FRC97_RS06860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FRC97_RS06865	COG0051	transcription antitermination factor activity, RNA binding
FRC97_RS06870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FRC97_RS06875	COG0088	Forms part of the polypeptide exit tunnel
FRC97_RS06880	COG0089	rRNA binding
FRC97_RS06885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FRC97_RS06890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FRC97_RS06895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FRC97_RS06900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FRC97_RS06905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FRC97_RS06910	COG0255	Belongs to the universal ribosomal protein uL29 family
FRC97_RS06915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FRC97_RS06920	COG0678	peroxiredoxin activity
FRC97_RS06930	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC97_RS06945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FRC97_RS06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FRC97_RS06965	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FRC97_RS06970	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FRC97_RS06975	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FRC97_RS06980	COG2205	protein histidine kinase activity
FRC97_RS06985	COG0745	RESPONSE REGULATOR receiver
FRC97_RS07005	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FRC97_RS07010	COG0321	lipoyl(octanoyl) transferase activity
FRC97_RS07015	COG2921	Belongs to the UPF0250 family
FRC97_RS07025	COG0356	it plays a direct role in the translocation of protons across the membrane
FRC97_RS07035	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FRC97_RS07040	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FRC97_RS07045	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FRC97_RS07050	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FRC97_RS07055	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FRC97_RS07060	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC97_RS07065	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FRC97_RS07065	COG1793	dna ligase
FRC97_RS07070	COG1793	dna ligase
FRC97_RS07075	COG1201	RNA secondary structure unwinding
FRC97_RS07125	COG3245	cytochrome
FRC97_RS07140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_RS07145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_RS07225	COG0121	glutamine amidotransferase
FRC97_RS07230	COG2814	Major facilitator Superfamily
FRC97_RS07235	COG1942	4-Oxalocrotonate Tautomerase
FRC97_RS07245	COG0840	transmembrane signaling receptor activity
FRC97_RS07250	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FRC97_RS07280	COG0018	arginyl-trna synthetase
FRC97_RS07290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FRC97_RS07300	COG1137	ATPase activity
FRC97_RS07305	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC97_RS07310	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FRC97_RS07330	COG4178	(ABC) transporter
FRC97_RS07340	COG0653	protein targeting
FRC97_RS07345	COG0659	secondary active sulfate transmembrane transporter activity
FRC97_RS07360	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FRC97_RS07380	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
FRC97_RS07395	COG2967	ApaG domain
FRC97_RS07400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FRC97_RS07410	COG0546	phosphoglycolate phosphatase activity
FRC97_RS07430	COG2207	Transcriptional regulator
FRC97_RS07450	COG4794	Type iii secretion
FRC97_RS07455	COG4790	Type iii secretion
FRC97_RS07470	COG4789	Type iii secretion
FRC97_RS07475	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FRC97_RS07595	COG0500	methyltransferase
FRC97_RS07600	COG1196	nuclear chromosome segregation
FRC97_RS07600	COG0739	heme binding
FRC97_RS07600	COG0741	lytic transglycosylase activity
FRC97_RS07625	COG0512	Glutamine amidotransferase of anthranilate synthase
FRC97_RS07630	COG1280	lysine exporter protein (LysE YggA)
FRC97_RS07635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC97_RS07645	COG0134	indole-3-glycerol-phosphate synthase activity
FRC97_RS07650	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FRC97_RS07690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FRC97_RS07700	COG0783	Belongs to the Dps family
FRC97_RS07705	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FRC97_RS07720	COG0463	Glycosyl transferase, family 2
FRC97_RS07735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FRC97_RS07745	COG3842	ATPase activity
FRC97_RS07750	COG3842	ATPase activity
FRC97_RS07760	COG0395	ABC-type sugar transport system, permease component
FRC97_RS07780	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FRC97_RS07785	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FRC97_RS07790	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FRC97_RS07795	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FRC97_RS07800	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FRC97_RS07805	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FRC97_RS07810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FRC97_RS07815	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FRC97_RS07820	COG1841	ribosomal large subunit assembly
FRC97_RS07825	COG0200	Binds to the 23S rRNA
FRC97_RS07830	COG0201	protein transport
FRC97_RS07835	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FRC97_RS07840	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FRC97_RS07845	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FRC97_RS07850	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FRC97_RS07855	COG0202	RNA polymerase activity
FRC97_RS07860	COG0203	ribosomal protein L17
FRC97_RS07870	COG0443	Heat shock 70 kDa protein
FRC97_RS07875	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC97_RS07880	COG0792	nuclease activity
FRC97_RS07885	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FRC97_RS07890	COG2823	Periplasmic or secreted lipoprotein
FRC97_RS07895	COG2084	Dehydrogenase
FRC97_RS07905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC97_RS07930	COG2733	membrane
FRC97_RS07950	COG0277	FAD linked oxidase domain protein
FRC97_RS07960	COG0583	DNA-binding transcription factor activity
FRC97_RS07980	COG1285	pathogenesis
FRC97_RS07990	COG3850	Histidine kinase
FRC97_RS07995	COG2197	response regulator
FRC97_RS08010	COG4771	TonB-dependent receptor
FRC97_RS08025	COG2223	nitrite transmembrane transporter activity
FRC97_RS08030	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
FRC97_RS08035	COG1140	nitrate reductase beta subunit
FRC97_RS08040	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
FRC97_RS08045	COG2181	nitrate reductase activity
FRC97_RS08050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_RS08055	COG0288	reversible hydration of carbon dioxide
FRC97_RS08070	COG3945	hemerythrin HHE cation binding domain
FRC97_RS08080	COG0477	Major facilitator Superfamily
FRC97_RS08125	COG1272	protein, Hemolysin III
FRC97_RS08185	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_RS08190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_RS08200	COG0129	dihydroxy-acid dehydratase activity
FRC97_RS08205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS08215	COG0583	DNA-binding transcription factor activity
FRC97_RS08220	COG1741	Belongs to the pirin family
FRC97_RS08225	COG1335	isochorismatase
FRC97_RS08265	COG0243	molybdopterin cofactor binding
FRC97_RS08280	COG1473	amidohydrolase
FRC97_RS08305	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_RS08315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_RS08370	COG3267	Type II secretory pathway component ExeA
FRC97_RS08370	COG3409	Peptidoglycan-binding domain 1 protein
FRC97_RS08375	COG3266	domain, Protein
FRC97_RS08390	COG4269	membrane
FRC97_RS08425	COG0625	glutathione transferase activity
FRC97_RS08430	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FRC97_RS08440	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FRC97_RS08445	COG1649	PFAM Uncharacterised BCR, COG1649
FRC97_RS08465	COG3447	MASE1 domain protein
FRC97_RS08465	COG5001	Diguanylate cyclase
FRC97_RS08465	COG5002	protein histidine kinase activity
FRC97_RS08470	COG0523	cobalamin synthesis protein
FRC97_RS08485	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FRC97_RS08490	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FRC97_RS08495	COG2001	Belongs to the MraZ family
FRC97_RS08500	COG0275	rRNA processing
FRC97_RS08505	COG3116	cell division
FRC97_RS08515	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FRC97_RS08520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FRC97_RS08525	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FRC97_RS08530	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FRC97_RS08535	COG0772	Belongs to the SEDS family
FRC97_RS08540	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FRC97_RS08545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC97_RS08550	COG1181	Belongs to the D-alanine--D-alanine ligase family
FRC97_RS08555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FRC97_RS08565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FRC97_RS08570	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FRC97_RS08580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FRC97_RS08585	COG0840	transmembrane signaling receptor activity
FRC97_RS08600	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FRC97_RS08605	COG0575	Belongs to the CDS family
FRC97_RS08630	COG1414	Transcriptional regulator
FRC97_RS08635	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_RS08640	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FRC97_RS08650	COG0557	exoribonuclease II activity
FRC97_RS08660	COG3150	esterase
FRC97_RS08665	COG0772	Belongs to the SEDS family
FRC97_RS08670	COG0154	amidase activity
FRC97_RS08675	COG0312	modulator of DNA gyrase
FRC97_RS08685	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FRC97_RS08695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FRC97_RS08705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FRC97_RS08710	COG0511	ligase activity, forming carbon-carbon bonds
FRC97_RS08715	COG0439	Biotin carboxylase
FRC97_RS08720	COG2264	protein methyltransferase activity
FRC97_RS08730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FRC97_RS08740	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FRC97_RS08775	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FRC97_RS08785	COG2204	response regulator
FRC97_RS08795	COG2205	protein histidine kinase activity
FRC97_RS08800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC97_RS08825	COG0431	NADPH-dependent FMN reductase
FRC97_RS08830	COG3829	transcription factor binding
FRC97_RS08835	COG1024	Enoyl-CoA hydratase
FRC97_RS08850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC97_RS08855	COG0633	Ferredoxin
FRC97_RS08855	COG3217	Mosc domain protein beta barrel domain protein
FRC97_RS08860	COG0012	GTP binding
FRC97_RS08870	COG0517	IMP dehydrogenase activity
FRC97_RS08870	COG1125	glycine betaine transport
FRC97_RS08880	COG1238	metal cluster binding
FRC97_RS08890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_RS08895	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FRC97_RS08900	COG0138	bifunctional purine biosynthesis protein purh
FRC97_RS08910	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FRC97_RS08915	COG0351	phosphomethylpyrimidine kinase
FRC97_RS08915	COG0352	thiamine-phosphate diphosphorylase activity
FRC97_RS08915	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FRC97_RS08920	COG1773	rubredoxin
FRC97_RS08935	COG0835	chemotaxis
FRC97_RS08940	COG0840	transmembrane signaling receptor activity
FRC97_RS08945	COG2198	Histidine kinase
FRC97_RS08945	COG0643	Histidine kinase
FRC97_RS08950	COG0415	Belongs to the DNA photolyase family
FRC97_RS08955	COG1678	Uncharacterized ACR, COG1678
FRC97_RS08960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FRC97_RS08965	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
FRC97_RS08970	COG0540	Belongs to the ATCase OTCase family
FRC97_RS08985	COG3842	ATPase activity
FRC97_RS08990	COG1178	ABC-type Fe3 transport system permease component
FRC97_RS09040	COG4970	Tfp pilus assembly protein FimT
FRC97_RS09060	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FRC97_RS09065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_RS09070	COG1765	OsmC-like protein
FRC97_RS09075	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FRC97_RS09095	COG1473	amidohydrolase
FRC97_RS09100	COG0747	negative chemotaxis
FRC97_RS09105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_RS09110	COG0444	Belongs to the ABC transporter superfamily
FRC97_RS09115	COG4608	Belongs to the ABC transporter superfamily
FRC97_RS09120	COG0840	transmembrane signaling receptor activity
FRC97_RS09130	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FRC97_RS09135	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FRC97_RS09140	COG0166	Belongs to the GPI family
FRC97_RS09145	COG0459	protein refolding
FRC97_RS09150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FRC97_RS09165	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FRC97_RS09200	COG2226	methyltransferase
FRC97_RS09205	COG0438	transferase activity, transferring glycosyl groups
FRC97_RS09215	COG0367	asparagine synthase
FRC97_RS09220	COG0438	transferase activity, transferring glycosyl groups
FRC97_RS09225	COG0367	asparagine synthase
FRC97_RS09245	COG1216	Glycosyl transferase, family 2
FRC97_RS09255	COG1309	transcriptional regulator
FRC97_RS09260	COG0493	'glutamate synthase
FRC97_RS09270	COG1953	Uracil, thiamine, allantoin
FRC97_RS09305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FRC97_RS09305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FRC97_RS09310	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC97_RS09325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FRC97_RS09335	COG1560	Kdo2-lipid A biosynthetic process
FRC97_RS09345	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FRC97_RS09355	COG1333	cytochrome c biogenesis protein
FRC97_RS09360	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FRC97_RS09365	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FRC97_RS09370	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FRC97_RS09400	COG1965	Belongs to the frataxin family
FRC97_RS09440	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FRC97_RS09445	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FRC97_RS09450	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FRC97_RS09470	COG0067	glutamate synthase
FRC97_RS09470	COG0069	glutamate synthase activity
FRC97_RS09470	COG0070	glutamate synthase
FRC97_RS09480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS09485	COG0765	amino acid transport
FRC97_RS09490	COG1126	abc transporter atp-binding protein
FRC97_RS09495	COG1127	ABC transporter
FRC97_RS09500	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FRC97_RS09505	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FRC97_RS09510	COG2853	Lipoprotein
FRC97_RS09530	COG1131	(ABC) transporter
FRC97_RS09535	COG0842	Transport permease protein
FRC97_RS09540	COG5007	Belongs to the BolA IbaG family
FRC97_RS09545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FRC97_RS09550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FRC97_RS09555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FRC97_RS09585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FRC97_RS09590	COG0131	Imidazoleglycerol-phosphate dehydratase
FRC97_RS09600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FRC97_RS09620	COG0438	transferase activity, transferring glycosyl groups
FRC97_RS09650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FRC97_RS09655	COG1301	dicarboxylic acid transport
FRC97_RS09665	COG0107	imidazoleglycerol-phosphate synthase activity
FRC97_RS09670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FRC97_RS09675	COG0140	phosphoribosyl-ATP diphosphatase activity
FRC97_RS09690	COG0537	adenosine 5'-monophosphoramidase activity
FRC97_RS09695	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC97_RS09700	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FRC97_RS09705	COG0805	protein transport
FRC97_RS09730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FRC97_RS09750	COG0714	Associated with various cellular activities
FRC97_RS09755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_RS09760	COG0084	hydrolase, TatD family'
FRC97_RS09770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FRC97_RS09775	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FRC97_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS09830	COG0840	transmembrane signaling receptor activity
FRC97_RS09835	COG0829	nickel cation binding
FRC97_RS09855	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC97_RS09880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS09885	COG1116	anion transmembrane transporter activity
FRC97_RS09900	COG0280	phosphate acetyltransferase
FRC97_RS09900	COG0281	malic enzyme
FRC97_RS09920	COG1953	Uracil, thiamine, allantoin
FRC97_RS09925	COG2186	Transcriptional regulator
FRC97_RS09930	COG0840	transmembrane signaling receptor activity
FRC97_RS09935	COG1301	dicarboxylic acid transport
FRC97_RS09970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC97_RS09985	COG2186	Transcriptional regulator
FRC97_RS09995	COG0405	Gamma-glutamyltransferase
FRC97_RS10035	COG0251	oxidation-reduction process
FRC97_RS10055	COG5002	protein histidine kinase activity
FRC97_RS10055	COG3447	MASE1 domain protein
FRC97_RS10055	COG5001	Diguanylate cyclase
FRC97_RS10070	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS10090	COG3845	ABC transporter
FRC97_RS10095	COG4603	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS10120	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FRC97_RS10135	COG2366	antibiotic biosynthetic process
FRC97_RS10140	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC97_RS10155	COG0717	Belongs to the dCTP deaminase family
FRC97_RS10170	COG2321	neutral zinc metallopeptidase
FRC97_RS10175	COG0513	Belongs to the DEAD box helicase family
FRC97_RS10180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FRC97_RS10185	COG2916	Histone family protein nucleoid-structuring protein H-NS
FRC97_RS10190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FRC97_RS10220	COG3483	tryptophan 2,3-dioxygenase activity
FRC97_RS10230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FRC97_RS10235	COG1522	sequence-specific DNA binding
FRC97_RS10240	COG0727	PFAM Uncharacterised protein family (UPF0153)
FRC97_RS10265	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FRC97_RS10270	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FRC97_RS10280	COG0579	oxidoreductase
FRC97_RS10285	COG0268	Binds directly to 16S ribosomal RNA
FRC97_RS10290	COG0728	peptidoglycan biosynthetic process
FRC97_RS10300	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC97_RS10300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FRC97_RS10310	COG3022	response to hydroperoxide
FRC97_RS10315	COG1530	ribonuclease E activity
FRC97_RS10340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FRC97_RS10340	COG0616	signal peptide processing
FRC97_RS10345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FRC97_RS10350	COG0424	maF-like protein
FRC97_RS10355	COG1399	metal-binding, possibly nucleic acid-binding protein
FRC97_RS10360	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FRC97_RS10365	COG0416	fatty acid biosynthetic process
FRC97_RS10370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FRC97_RS10375	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FRC97_RS10380	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS10385	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC97_RS10390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FRC97_RS10410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FRC97_RS10415	COG0481	GTPase activity
FRC97_RS10420	COG0681	Belongs to the peptidase S26 family
FRC97_RS10430	COG0571	ribonuclease III activity
FRC97_RS10435	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FRC97_RS10440	COG1381	Involved in DNA repair and RecF pathway recombination
FRC97_RS10445	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FRC97_RS10455	COG1472	Belongs to the glycosyl hydrolase 3 family
FRC97_RS10460	COG3064	Membrane
FRC97_RS10470	COG5001	Diguanylate cyclase
FRC97_RS10470	COG4251	negative regulation of phosphorylation
FRC97_RS10470	COG3706	GGDEF domain
FRC97_RS10470	COG2203	Gaf domain
FRC97_RS10475	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FRC97_RS10500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FRC97_RS10515	COG0762	integral membrane protein
FRC97_RS10520	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FRC97_RS10525	COG0159	tryptophan synthase activity
FRC97_RS10530	COG0133	tryptophan synthase activity
FRC97_RS10535	COG0135	phosphoribosylanthranilate isomerase activity
FRC97_RS10540	COG0101	tRNA pseudouridine synthase activity
FRC97_RS10550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FRC97_RS10560	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_RS10565	COG0066	3-isopropylmalate dehydratase activity
FRC97_RS10575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FRC97_RS10585	COG0484	heat shock protein binding
FRC97_RS10590	COG0443	Heat shock 70 kDa protein
FRC97_RS10595	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FRC97_RS10600	COG0360	Binds together with S18 to 16S ribosomal RNA
FRC97_RS10610	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FRC97_RS10615	COG0359	binds to the 23S rRNA
FRC97_RS10630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FRC97_RS10635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRC97_RS10645	COG0436	Aminotransferase
FRC97_RS10660	COG1763	Mo-molybdopterin cofactor biosynthetic process
FRC97_RS10665	COG0303	'Molybdopterin
FRC97_RS10670	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FRC97_RS10675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_RS10700	COG0314	molybdopterin synthase activity
FRC97_RS10705	COG0542	response to heat
FRC97_RS10725	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FRC97_RS10735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_RS10740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_RS10750	COG0436	Aminotransferase
FRC97_RS10755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FRC97_RS10760	COG1185	polyribonucleotide nucleotidyltransferase activity
FRC97_RS10765	COG0604	alcohol dehydrogenase
FRC97_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS10765	COG3321	synthase
FRC97_RS10770	COG0149	triose-phosphate isomerase activity
FRC97_RS10785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_RS10790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_RS10795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_RS10800	COG0649	NAD binding
FRC97_RS10805	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FRC97_RS10810	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRC97_RS10815	COG1034	ATP synthesis coupled electron transport
FRC97_RS10820	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FRC97_RS10825	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FRC97_RS10835	COG0713	ATP synthesis coupled electron transport
FRC97_RS10850	COG1007	ATP synthesis coupled electron transport
FRC97_RS10865	COG1132	(ABC) transporter
FRC97_RS10910	COG0463	Glycosyl transferase, family 2
FRC97_RS10910	COG0457	Tetratricopeptide repeat
FRC97_RS10930	COG0071	Belongs to the small heat shock protein (HSP20) family
FRC97_RS10935	COG1136	(ABC) transporter
FRC97_RS10940	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FRC97_RS10945	COG0702	epimerase
FRC97_RS10950	COG1733	regulation of RNA biosynthetic process
FRC97_RS10955	COG2267	carboxylic ester hydrolase activity
FRC97_RS10960	COG0584	glycerophosphoryl diester phosphodiesterase
FRC97_RS10970	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FRC97_RS10975	COG0586	Pfam SNARE associated Golgi protein
FRC97_RS10980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FRC97_RS10995	COG0860	N-Acetylmuramoyl-L-alanine amidase
FRC97_RS11000	COG0802	atpase or kinase
FRC97_RS11005	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FRC97_RS11035	COG4974	Belongs to the 'phage' integrase family
FRC97_RS11040	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS11045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC97_RS11050	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FRC97_RS11055	COG2833	Protein of unknown function (DUF455)
FRC97_RS11065	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FRC97_RS11075	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FRC97_RS11080	COG0148	phosphopyruvate hydratase activity
FRC97_RS11100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FRC97_RS11105	COG0504	CTP synthase activity
FRC97_RS11110	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FRC97_RS11115	COG0756	dUTP diphosphatase activity
FRC97_RS11125	COG1047	Peptidyl-prolyl cis-trans
FRC97_RS11130	COG2850	peptidyl-arginine hydroxylation
FRC97_RS11145	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FRC97_RS11150	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FRC97_RS11155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_RS11180	COG0741	lytic transglycosylase activity
FRC97_RS11190	COG0840	transmembrane signaling receptor activity
FRC97_RS11195	COG0840	transmembrane signaling receptor activity
FRC97_RS11200	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
FRC97_RS11235	COG2308	Evidence 4 Homologs of previously reported genes of
FRC97_RS11255	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FRC97_RS11270	COG4628	conserved protein (DUF2132)
FRC97_RS11280	COG0657	acetylesterase activity
FRC97_RS11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FRC97_RS11310	COG4774	siderophore transport
FRC97_RS11355	COG3634	alkyl hydroperoxide reductase activity
FRC97_RS11380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FRC97_RS11395	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FRC97_RS11420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS11435	COG0583	DNA-binding transcription factor activity
FRC97_RS11440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_RS11450	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS11455	COG4948	Mandelate Racemase Muconate Lactonizing
FRC97_RS11500	COG0840	transmembrane signaling receptor activity
FRC97_RS11505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FRC97_RS11510	COG0358	DNA primase activity
FRC97_RS11515	COG5001	Diguanylate cyclase
FRC97_RS11515	COG3300	MHYT domain
FRC97_RS11520	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS11525	COG0405	Gamma-glutamyltransferase
FRC97_RS11530	COG3540	Alkaline phosphatase
FRC97_RS11540	COG0604	alcohol dehydrogenase
FRC97_RS11540	COG3321	synthase
FRC97_RS11540	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS11545	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FRC97_RS11550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FRC97_RS11560	COG0564	pseudouridine synthase activity
FRC97_RS11565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FRC97_RS11570	COG1187	pseudouridine synthase activity
FRC97_RS11575	COG0105	UTP biosynthetic process
FRC97_RS11580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FRC97_RS11585	COG3063	Type IV pilus biogenesis stability protein PilW
FRC97_RS11595	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FRC97_RS11600	COG0124	histidyl-tRNA synthetase
FRC97_RS11615	COG1160	GTP binding
FRC97_RS11620	COG1923	regulation of RNA biosynthetic process
FRC97_RS11625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FRC97_RS11630	COG0330	HflC and HflK could
FRC97_RS11635	COG0330	HflC and HflK could
FRC97_RS11640	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FRC97_RS11645	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FRC97_RS11650	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FRC97_RS11680	COG1187	pseudouridine synthase activity
FRC97_RS11710	COG0174	glutamine synthetase
FRC97_RS11720	COG3852	Histidine kinase
FRC97_RS11735	COG0708	Exodeoxyribonuclease III
FRC97_RS11750	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FRC97_RS11760	COG0277	FAD linked oxidase domain protein
FRC97_RS11770	COG1295	ribonuclease BN
FRC97_RS11775	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
FRC97_RS11800	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC97_RS11805	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FRC97_RS11810	COG0740	serine-type endopeptidase activity
FRC97_RS11815	COG0544	peptidyl-prolyl cis-trans isomerase activity
FRC97_RS11825	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_RS11835	COG1562	ergosterol biosynthetic process
FRC97_RS11865	COG0631	protein serine/threonine phosphatase activity
FRC97_RS11880	COG2885	chlorophyll binding
FRC97_RS11945	COG1451	nucleotide metabolic process
FRC97_RS11950	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS11955	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
FRC97_RS11960	COG2080	2 iron, 2 sulfur cluster binding
FRC97_RS11965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FRC97_RS11980	COG0114	fumarate hydratase activity
FRC97_RS11990	COG0745	RESPONSE REGULATOR receiver
FRC97_RS11995	COG2205	protein histidine kinase activity
FRC97_RS12000	COG2113	Glycine betaine
FRC97_RS12005	COG4176	ABC-type proline glycine betaine transport system permease component
FRC97_RS12010	COG4175	Glycine betaine
FRC97_RS12020	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FRC97_RS12045	COG4654	Cytochrome c, class I
FRC97_RS12055	COG0129	dihydroxy-acid dehydratase activity
FRC97_RS12070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FRC97_RS12075	COG1802	Transcriptional regulator
FRC97_RS12095	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS12105	COG0589	response to stress
FRC97_RS12115	COG2217	Heavy metal translocating P-type atpase
FRC97_RS12125	COG3278	Belongs to the heme-copper respiratory oxidase family
FRC97_RS12160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FRC97_RS12165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC97_RS12175	COG3437	response regulator, receiver
FRC97_RS12195	COG4206	TonB-dependent receptor
FRC97_RS12200	COG1797	cobyrinic acid a,c-diamide synthase activity
FRC97_RS12215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC97_RS12220	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC97_RS12225	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
FRC97_RS12230	COG0778	Nitroreductase
FRC97_RS12235	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC97_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS12270	COG1492	cobalamin metabolic process
FRC97_RS12275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FRC97_RS12300	COG0477	Major facilitator Superfamily
FRC97_RS12320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FRC97_RS12325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_RS12330	COG2900	Belongs to the SlyX family
FRC97_RS12345	COG0513	Belongs to the DEAD box helicase family
FRC97_RS12370	COG1959	2 iron, 2 sulfur cluster binding
FRC97_RS12375	COG0583	DNA-binding transcription factor activity
FRC97_RS12390	COG0560	Phosphoserine phosphatase
FRC97_RS12400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC97_RS12410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FRC97_RS12415	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC97_RS12415	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC97_RS12420	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FRC97_RS12420	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FRC97_RS12440	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS12450	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC97_RS12490	COG0693	protein deglycase activity
FRC97_RS12500	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
FRC97_RS12505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FRC97_RS12520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FRC97_RS12535	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS12540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_RS12560	COG1446	asparaginase
FRC97_RS12565	COG4172	Belongs to the ABC transporter superfamily
FRC97_RS12575	COG0601	transmembrane transport
FRC97_RS12580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_RS12600	COG0322	excinuclease ABC activity
FRC97_RS12640	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FRC97_RS12765	COG0737	Belongs to the 5'-nucleotidase family
FRC97_RS12790	COG1193	negative regulation of DNA recombination
FRC97_RS12810	COG2003	Belongs to the UPF0758 family
FRC97_RS12815	COG1047	Peptidyl-prolyl cis-trans
FRC97_RS12820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FRC97_RS12825	COG1253	flavin adenine dinucleotide binding
FRC97_RS12830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
FRC97_RS12830	COG0617	tRNA 3'-terminal CCA addition
FRC97_RS12830	COG0517	IMP dehydrogenase activity
FRC97_RS12835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FRC97_RS12840	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FRC97_RS12880	COG0129	dihydroxy-acid dehydratase activity
FRC97_RS12895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS12900	COG0765	amino acid transport
FRC97_RS12905	COG0765	amino acid transport
FRC97_RS12910	COG0612	Peptidase, M16
FRC97_RS12920	COG3209	COG3209 Rhs family protein
FRC97_RS12955	COG0038	chloride channel
FRC97_RS13000	COG0443	Heat shock 70 kDa protein
FRC97_RS13060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FRC97_RS13065	COG4774	siderophore transport
FRC97_RS13075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC97_RS13140	COG3209	COG3209 Rhs family protein
FRC97_RS13145	COG0180	Tryptophanyl-tRNA synthetase
FRC97_RS13150	COG1994	Peptidase M50
FRC97_RS13160	COG0009	L-threonylcarbamoyladenylate synthase
FRC97_RS13165	COG0613	PHP domain protein
FRC97_RS13170	COG0738	Major facilitator superfamily
FRC97_RS13185	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FRC97_RS13195	COG4591	ABC-type transport system involved in lipoprotein release permease component
FRC97_RS13200	COG1136	(ABC) transporter
FRC97_RS13205	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FRC97_RS13210	COG1970	mechanosensitive ion channel activity
FRC97_RS13215	COG0723	plastoquinol--plastocyanin reductase activity
FRC97_RS13220	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FRC97_RS13225	COG2857	Cytochrome c1
FRC97_RS13230	COG0625	glutathione transferase activity
FRC97_RS13235	COG2969	positive regulation of protein catabolic process
FRC97_RS13250	COG0739	heme binding
FRC97_RS13255	COG0653	protein targeting
FRC97_RS13260	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FRC97_RS13270	COG0494	nUDIX hydrolase
FRC97_RS13275	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FRC97_RS13280	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FRC97_RS13285	COG0237	dephospho-CoA kinase activity
FRC97_RS13305	COG0583	DNA-binding transcription factor activity
FRC97_RS13315	COG1473	amidohydrolase
FRC97_RS13325	COG0142	geranyltranstransferase activity
FRC97_RS13330	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FRC97_RS13335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FRC97_RS13340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FRC97_RS13345	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FRC97_RS13350	COG0494	nUDIX hydrolase
FRC97_RS13355	COG0442	prolyl-tRNA aminoacylation
FRC97_RS13365	COG1253	flavin adenine dinucleotide binding
FRC97_RS13370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FRC97_RS13375	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FRC97_RS13385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FRC97_RS13390	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FRC97_RS13420	COG1511	domain protein
FRC97_RS13420	COG3264	Mechanosensitive ion channel
FRC97_RS13425	COG0584	glycerophosphoryl diester phosphodiesterase
FRC97_RS13435	COG3842	ATPase activity
FRC97_RS13440	COG0395	ABC-type sugar transport system, permease component
FRC97_RS13445	COG1175	transmembrane transport
FRC97_RS13450	COG1653	transport
FRC97_RS13455	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_RS13480	COG2226	methyltransferase
FRC97_RS13495	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FRC97_RS13515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FRC97_RS13525	COG0494	nUDIX hydrolase
FRC97_RS13530	COG0745	RESPONSE REGULATOR receiver
FRC97_RS13540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_RS13545	COG0302	gtp cyclohydrolase
FRC97_RS13575	COG1609	Transcriptional regulator
FRC97_RS13605	COG0747	negative chemotaxis
FRC97_RS13615	COG4608	Belongs to the ABC transporter superfamily
FRC97_RS13620	COG0444	Belongs to the ABC transporter superfamily
FRC97_RS13625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_RS13635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FRC97_RS13640	COG0193	aminoacyl-tRNA hydrolase activity
FRC97_RS13645	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FRC97_RS13650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FRC97_RS13660	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FRC97_RS13675	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC97_RS13685	COG1194	a g-specific adenine glycosylase
FRC97_RS13690	COG1660	Displays ATPase and GTPase activities
FRC97_RS13695	COG0497	DNA recombination
FRC97_RS13700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FRC97_RS13770	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_RS13775	COG1420	regulation of RNA biosynthetic process
FRC97_RS13785	COG2197	response regulator
FRC97_RS13790	COG3693	PFAM glycoside hydrolase, family 10
FRC97_RS13820	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FRC97_RS13825	COG1758	RNA polymerase activity
FRC97_RS13830	COG0194	GDP metabolic process
FRC97_RS13835	COG1561	YicC-like family, N-terminal region
FRC97_RS13855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FRC97_RS13860	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FRC97_RS13875	COG4221	oxidoreductase activity
FRC97_RS13880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_RS13895	COG1595	DNA-templated transcription, initiation
FRC97_RS13920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FRC97_RS13925	COG0784	Response regulator, receiver
FRC97_RS13925	COG4191	Histidine kinase
FRC97_RS13970	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC97_RS13970	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FRC97_RS13995	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC97_RS14000	COG4968	Prepilin-type N-terminal cleavage methylation domain
FRC97_RS14025	COG1063	alcohol dehydrogenase
FRC97_RS14035	COG2205	protein histidine kinase activity
FRC97_RS14040	COG2249	NAD(P)H dehydrogenase (quinone) activity
FRC97_RS14055	COG0464	growth
FRC97_RS14070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FRC97_RS14075	COG0830	nickel cation binding
FRC97_RS14080	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
FRC97_RS14090	COG0804	urea catabolic process
FRC97_RS14095	COG0832	Belongs to the urease beta subunit family
FRC97_RS14105	COG0831	urea catabolic process
FRC97_RS14120	COG5001	Diguanylate cyclase
FRC97_RS14140	COG1304	FMN binding
FRC97_RS14145	COG2205	protein histidine kinase activity
FRC97_RS14165	COG2814	Major facilitator Superfamily
FRC97_RS14170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FRC97_RS14175	COG4336	lyase activity
FRC97_RS14180	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FRC97_RS14185	COG4770	biotin carboxylase activity
FRC97_RS14195	COG3038	cytochrome b561
FRC97_RS14215	COG5599	Phosphatase
FRC97_RS14220	COG1301	dicarboxylic acid transport
FRC97_RS14265	COG2814	Major facilitator Superfamily
FRC97_RS14365	COG0697	spore germination
FRC97_RS14400	COG0583	DNA-binding transcription factor activity
FRC97_RS14415	COG1283	sodium-dependent phosphate transmembrane transporter activity
FRC97_RS14425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FRC97_RS14430	COG3842	ATPase activity
FRC97_RS14440	COG1177	transmembrane transport
FRC97_RS14445	COG4149	molybdate abc transporter
FRC97_RS14455	COG1609	Transcriptional regulator
FRC97_RS14470	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FRC97_RS14480	COG0196	riboflavin kinase activity
FRC97_RS14490	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS14500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_RS14515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_RS14535	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS14540	COG3132	Protein of unknown function, DUF480
FRC97_RS14545	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FRC97_RS14560	COG3866	Pectate lyase
FRC97_RS14565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_RS14565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FRC97_RS14580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FRC97_RS14585	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FRC97_RS14590	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FRC97_RS14595	COG0492	ferredoxin-NADP+ reductase activity
FRC97_RS14600	COG1674	ftsk spoiiie
FRC97_RS14605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FRC97_RS14620	COG1573	uracil-dna glycosylase
FRC97_RS14625	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FRC97_RS14630	COG0840	transmembrane signaling receptor activity
FRC97_RS14635	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS14655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FRC97_RS14655	COG2885	chlorophyll binding
FRC97_RS14660	COG1392	Phosphate transport regulator
FRC97_RS14665	COG0306	phosphate transporter
FRC97_RS14680	COG0228	four-way junction DNA binding
FRC97_RS14685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FRC97_RS14690	COG0336	Belongs to the RNA methyltransferase TrmD family
FRC97_RS14695	COG0335	large ribosomal subunit rRNA binding
FRC97_RS14705	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FRC97_RS14710	COG1162	GTPase activity
FRC97_RS14715	COG2154	pterin-4-alpha-carbinolamine dehydratase
FRC97_RS14725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FRC97_RS14730	COG0513	Belongs to the DEAD box helicase family
FRC97_RS14735	COG3447	MASE1 domain protein
FRC97_RS14735	COG5001	Diguanylate cyclase
FRC97_RS14735	COG5002	protein histidine kinase activity
FRC97_RS14740	COG2814	Major facilitator Superfamily
FRC97_RS14755	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FRC97_RS14760	COG5002	protein histidine kinase activity
FRC97_RS14765	COG2204	response regulator
FRC97_RS14815	COG0516	GMP reductase activity
FRC97_RS14900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FRC97_RS14940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS14945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FRC97_RS14975	COG0412	Dienelactone hydrolase
FRC97_RS14985	COG0165	Argininosuccinate lyase
FRC97_RS14995	COG3275	phosphorelay sensor kinase activity
FRC97_RS15000	COG0165	Argininosuccinate lyase
FRC97_RS15035	COG0840	transmembrane signaling receptor activity
FRC97_RS15040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_RS15050	COG1304	FMN binding
FRC97_RS15055	COG0840	transmembrane signaling receptor activity
FRC97_RS15075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FRC97_RS15100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FRC97_RS15105	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FRC97_RS15115	COG0617	tRNA 3'-terminal CCA addition
FRC97_RS15155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS15160	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS15165	COG0583	DNA-binding transcription factor activity
FRC97_RS15210	COG2816	NAD+ diphosphatase activity
FRC97_RS15215	COG0425	Belongs to the sulfur carrier protein TusA family
FRC97_RS15225	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FRC97_RS15230	COG0525	valine-tRNA ligase activity
FRC97_RS15235	COG0501	Belongs to the peptidase M48B family
FRC97_RS15245	COG0488	(ABC) transporter
FRC97_RS15265	COG0181	hydroxymethylbilane synthase activity
FRC97_RS15270	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FRC97_RS15275	COG1289	transmembrane transporter activity
FRC97_RS15285	COG1289	transmembrane transporter activity
FRC97_RS15290	COG0628	permease
FRC97_RS15345	COG1722	exodeoxyribonuclease VII activity
FRC97_RS15350	COG0142	geranyltranstransferase activity
FRC97_RS15355	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FRC97_RS15360	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FRC97_RS15380	COG0668	transmembrane transport
FRC97_RS15385	COG0366	Alpha amylase catalytic
FRC97_RS15390	COG0366	Alpha amylase catalytic
FRC97_RS15395	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FRC97_RS15400	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FRC97_RS15405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FRC97_RS15425	COG2005	Transcriptional regulator
FRC97_RS15425	COG3585	molybdate ion transport
FRC97_RS15435	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FRC97_RS15445	COG1280	lysine exporter protein (LysE YggA)
FRC97_RS15450	COG3279	Response regulator of the LytR AlgR family
FRC97_RS15455	COG3275	phosphorelay sensor kinase activity
FRC97_RS15485	COG1968	undecaprenyl-diphosphatase activity
FRC97_RS15490	COG5002	protein histidine kinase activity
FRC97_RS15490	COG5001	Diguanylate cyclase
FRC97_RS15490	COG3447	MASE1 domain protein
FRC97_RS15515	COG3209	COG3209 Rhs family protein
FRC97_RS15530	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FRC97_RS15535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FRC97_RS15590	COG0784	Response regulator, receiver
FRC97_RS15590	COG2205	protein histidine kinase activity
FRC97_RS15590	COG5002	protein histidine kinase activity
FRC97_RS15595	COG3437	response regulator, receiver
FRC97_RS15605	COG1132	(ABC) transporter
FRC97_RS15625	COG0483	inositol monophosphate 1-phosphatase activity
FRC97_RS15640	COG4555	ABC transporter
FRC97_RS15655	COG1045	serine acetyltransferase
FRC97_RS15660	COG0521	Mo-molybdopterin cofactor biosynthetic process
FRC97_RS15665	COG3028	Belongs to the UPF0307 family
FRC97_RS15670	COG0312	modulator of DNA gyrase
FRC97_RS15685	COG2721	sulfolactate sulfo-lyase activity
FRC97_RS15700	COG0477	Major facilitator Superfamily
FRC97_RS15705	COG1752	Esterase of the alpha-beta hydrolase superfamily
FRC97_RS15710	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_RS15715	COG0583	DNA-binding transcription factor activity
FRC97_RS15725	COG0625	glutathione transferase activity
FRC97_RS15730	COG1610	YqeY-like protein
FRC97_RS15735	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FRC97_RS15755	COG0640	Transcriptional regulator
FRC97_RS15760	COG2081	HI0933 family
FRC97_RS15775	COG0288	reversible hydration of carbon dioxide
FRC97_RS15780	COG1607	acyl-coa hydrolase
FRC97_RS15785	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
FRC97_RS15785	COG5297	Belongs to the glycosyl hydrolase family 6
FRC97_RS15795	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FRC97_RS15800	COG0243	molybdopterin cofactor binding
FRC97_RS15810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FRC97_RS15815	COG0840	transmembrane signaling receptor activity
FRC97_RS15830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_RS15840	COG0840	transmembrane signaling receptor activity
FRC97_RS15845	COG0516	GMP reductase activity
FRC97_RS15845	COG0517	IMP dehydrogenase activity
FRC97_RS15865	COG0643	Histidine kinase
FRC97_RS15865	COG2198	Histidine kinase
FRC97_RS15870	COG0840	transmembrane signaling receptor activity
FRC97_RS15880	COG0745	RESPONSE REGULATOR receiver
FRC97_RS15895	COG2223	nitrite transmembrane transporter activity
FRC97_RS15900	COG3959	Transketolase, thiamine diphosphate binding domain
FRC97_RS15905	COG3958	Transketolase
FRC97_RS15910	COG0194	GDP metabolic process
FRC97_RS15925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FRC97_RS15940	COG0626	cystathionine gamma-synthase activity
FRC97_RS15950	COG0724	RNA recognition motif
FRC97_RS15965	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FRC97_RS15970	COG1116	anion transmembrane transporter activity
FRC97_RS15975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS15980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC97_RS16000	COG0683	leucine binding
FRC97_RS16005	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FRC97_RS16020	COG0683	leucine binding
FRC97_RS16050	COG2951	lytic endotransglycosylase activity
FRC97_RS16065	COG0714	Associated with various cellular activities
FRC97_RS16070	COG0123	including yeast histone deacetylase and acetoin utilization protein
FRC97_RS16075	COG1024	Enoyl-CoA hydratase
FRC97_RS16145	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FRC97_RS16170	COG3048	D-serine ammonia-lyase activity
FRC97_RS16175	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS16180	COG0154	amidase activity
FRC97_RS16200	COG1739	Uncharacterized protein family UPF0029
FRC97_RS16215	COG0840	transmembrane signaling receptor activity
FRC97_RS16230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS16240	COG0556	nucleotide-excision repair
FRC97_RS16245	COG1959	2 iron, 2 sulfur cluster binding
FRC97_RS16250	COG1104	cysteine desulfurase activity
FRC97_RS16255	COG0822	iron-sulfur transferase activity
FRC97_RS16265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FRC97_RS16270	COG0443	Heat shock 70 kDa protein
FRC97_RS16275	COG0633	Ferredoxin
FRC97_RS16300	COG0579	oxidoreductase
FRC97_RS16320	COG0167	dihydroorotate dehydrogenase activity
FRC97_RS16325	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FRC97_RS16340	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FRC97_RS16345	COG4566	intracellular signal transduction
FRC97_RS16355	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FRC97_RS16360	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC97_RS16365	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC97_RS16390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FRC97_RS16395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FRC97_RS16405	COG0515	serine threonine protein kinase
FRC97_RS16435	COG3243	poly(R)-hydroxyalkanoic acid synthase
FRC97_RS16440	COG0183	Belongs to the thiolase family
FRC97_RS16445	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS16450	COG0488	(ABC) transporter
FRC97_RS16455	COG2890	protein-(glutamine-N5) methyltransferase activity
FRC97_RS16460	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FRC97_RS16470	COG2171	N-acyltransferase activity
FRC97_RS16480	COG0840	transmembrane signaling receptor activity
FRC97_RS16485	COG2878	Part of a membrane complex involved in electron transport
FRC97_RS16505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FRC97_RS16520	COG3039	Transposase
FRC97_RS16535	COG0840	transmembrane signaling receptor activity
FRC97_RS16605	COG1802	Transcriptional regulator
FRC97_RS16610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC97_RS16610	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
FRC97_RS16620	COG1703	isobutyryl-CoA mutase activity
FRC97_RS16625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FRC97_RS16635	COG4770	biotin carboxylase activity
FRC97_RS16655	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FRC97_RS16740	COG5002	protein histidine kinase activity
FRC97_RS16755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FRC97_RS16770	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FRC97_RS16775	COG0583	DNA-binding transcription factor activity
FRC97_RS16780	COG2814	Major facilitator Superfamily
FRC97_RS16790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FRC97_RS16795	COG2011	ABC-type metal ion transport system permease component
FRC97_RS16815	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FRC97_RS16835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FRC97_RS16840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FRC97_RS16845	COG4208	sulfate ABC transporter
FRC97_RS16850	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FRC97_RS16855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FRC97_RS16880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FRC97_RS16880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FRC97_RS16885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS16895	COG1643	Atp-dependent helicase
FRC97_RS16905	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FRC97_RS16910	COG0252	asparaginase activity
FRC97_RS16920	COG0563	adenylate kinase activity
FRC97_RS16925	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FRC97_RS16930	COG2835	tetraacyldisaccharide 4'-kinase activity
FRC97_RS16935	COG1663	tetraacyldisaccharide 4'-kinase activity
FRC97_RS16940	COG0848	biopolymer transport protein
FRC97_RS16945	COG0811	peptide transport
FRC97_RS16950	COG1570	exodeoxyribonuclease VII activity
FRC97_RS16955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FRC97_RS16985	COG0625	glutathione transferase activity
FRC97_RS16990	COG1942	4-Oxalocrotonate Tautomerase
FRC97_RS17005	COG2814	Major facilitator Superfamily
FRC97_RS17010	COG0789	Transcriptional regulator
FRC97_RS17050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FRC97_RS17055	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS17065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FRC97_RS17075	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS17090	COG2721	sulfolactate sulfo-lyase activity
FRC97_RS17105	COG4772	TonB-dependent receptor
FRC97_RS17110	COG2032	superoxide dismutase activity
FRC97_RS17125	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS17150	COG1113	amino acid transport
FRC97_RS17160	COG0505	Belongs to the CarA family
FRC97_RS17165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FRC97_RS17170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FRC97_RS17185	COG1534	Rna-binding protein
FRC97_RS17190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FRC97_RS17195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FRC97_RS17205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FRC97_RS17235	COG0248	Ppx GppA phosphatase
FRC97_RS17240	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FRC97_RS17245	COG0573	inorganic phosphate transmembrane transporter activity
FRC97_RS17250	COG0581	inorganic phosphate transmembrane transporter activity
FRC97_RS17255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FRC97_RS17260	COG0704	Plays a role in the regulation of phosphate uptake
FRC97_RS17275	COG0534	Mate efflux family protein
FRC97_RS17285	COG0254	rRNA binding
FRC97_RS17290	COG0420	3'-5' exonuclease activity
FRC97_RS17295	COG0419	ATPase involved in DNA repair
FRC97_RS17300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FRC97_RS17315	COG1074	ATP-dependent DNA helicase activity
FRC97_RS17320	COG2081	HI0933 family
FRC97_RS17335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FRC97_RS17340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FRC97_RS17345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FRC97_RS17365	COG1388	LysM domain
FRC97_RS17365	COG0741	lytic transglycosylase activity
FRC97_RS17370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FRC97_RS17430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_RS17435	COG2226	methyltransferase
FRC97_RS17440	COG0328	RNA-DNA hybrid ribonuclease activity
FRC97_RS17455	COG0303	'Molybdopterin
FRC97_RS17465	COG0746	molybdenum cofactor guanylyltransferase activity
FRC97_RS17470	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FRC97_RS17495	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_RS17520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FRC97_RS17535	COG0587	DNA-directed DNA polymerase activity
FRC97_RS17540	COG2982	Protein involved in outer membrane biogenesis
FRC97_RS17545	COG0564	pseudouridine synthase activity
FRC97_RS17575	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FRC97_RS17585	COG0431	NADPH-dependent FMN reductase
FRC97_RS17590	COG0583	DNA-binding transcription factor activity
FRC97_RS17635	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS17640	COG0346	lactoylglutathione lyase activity
FRC97_RS17650	COG0800	Aldolase
FRC97_RS17660	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FRC97_RS17665	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FRC97_RS17670	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
FRC97_RS17675	COG3265	gluconokinase activity
FRC97_RS17680	COG1609	Transcriptional regulator
FRC97_RS17705	COG0259	pyridoxamine-phosphate oxidase activity
FRC97_RS17720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS17725	COG4771	TonB-dependent receptor
FRC97_RS17750	COG1136	(ABC) transporter
FRC97_RS17760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC97_RS17765	COG1309	transcriptional regulator
FRC97_RS17785	COG0045	succinate-CoA ligase (ADP-forming) activity
FRC97_RS17785	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC97_RS17785	COG1042	CoA-binding domain protein
FRC97_RS17835	COG2133	pyrroloquinoline quinone binding
FRC97_RS17840	COG0791	NLP P60 protein
FRC97_RS17885	COG3209	COG3209 Rhs family protein
FRC97_RS17905	COG5484	DNA packaging
FRC97_RS17905	COG3728	DNA packaging
FRC97_RS17950	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FRC97_RS17965	COG4128	Pfam Zonular occludens toxin
FRC97_RS18020	COG0527	aspartate kinase activity
FRC97_RS18025	COG0037	tRNA processing
FRC97_RS18040	COG0215	cysteine-tRNA ligase activity
FRC97_RS18095	COG1522	sequence-specific DNA binding
FRC97_RS18115	COG3384	dioxygenase
FRC97_RS18130	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FRC97_RS18140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_RS18155	COG1309	transcriptional regulator
FRC97_RS18195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FRC97_RS18225	COG0840	transmembrane signaling receptor activity
FRC97_RS18255	COG0564	pseudouridine synthase activity
FRC97_RS18260	COG1285	pathogenesis
FRC97_RS18275	COG2814	Major facilitator Superfamily
FRC97_RS18295	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
FRC97_RS18310	COG5002	protein histidine kinase activity
FRC97_RS18325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC97_RS18335	COG2918	glutathione biosynthetic process
FRC97_RS18345	COG3386	PFAM SMP-30 Gluconolaconase
FRC97_RS18365	COG1879	ABC-type sugar transport system periplasmic component
FRC97_RS18370	COG4213	ABC transporter substrate-binding protein
FRC97_RS18380	COG4214	carbohydrate transport
FRC97_RS18390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS18395	COG1172	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS18410	COG3734	2-keto-3-deoxy-galactonokinase
FRC97_RS18415	COG0800	Aldolase
FRC97_RS18420	COG4948	Mandelate Racemase Muconate Lactonizing
FRC97_RS18425	COG1289	transmembrane transporter activity
FRC97_RS18445	COG2201	protein-glutamate methylesterase activity
FRC97_RS18450	COG0745	RESPONSE REGULATOR receiver
FRC97_RS18460	COG2202	Pas domain
FRC97_RS18460	COG2205	protein histidine kinase activity
FRC97_RS18485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FRC97_RS18490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FRC97_RS18495	COG0436	Aminotransferase
FRC97_RS18500	COG0824	Thioesterase
FRC97_RS18520	COG0477	Major facilitator Superfamily
FRC97_RS18525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FRC97_RS18530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FRC97_RS18535	COG1845	cytochrome c oxidase, subunit III
FRC97_RS18540	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FRC97_RS18565	COG0583	DNA-binding transcription factor activity
FRC97_RS18570	COG0826	peptidase U32
FRC97_RS18585	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FRC97_RS18590	COG1049	propionate catabolic process, 2-methylcitrate cycle
FRC97_RS18605	COG4106	trans-aconitate 2-methyltransferase activity
FRC97_RS18610	COG0039	L-malate dehydrogenase activity
FRC97_RS18615	COG2188	Transcriptional regulator
FRC97_RS18630	COG1053	succinate dehydrogenase
FRC97_RS18635	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FRC97_RS18640	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FRC97_RS18645	COG0372	Belongs to the citrate synthase family
FRC97_RS18660	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FRC97_RS18665	COG4977	sequence-specific DNA binding
FRC97_RS18675	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FRC97_RS18680	COG2194	sulfuric ester hydrolase activity
FRC97_RS18690	COG0473	3-isopropylmalate dehydrogenase activity
FRC97_RS18700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FRC97_RS18705	COG0601	transmembrane transport
FRC97_RS18715	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS18735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FRC97_RS18745	COG1522	sequence-specific DNA binding
FRC97_RS18750	COG1473	amidohydrolase
FRC97_RS18795	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS18810	COG3264	Mechanosensitive ion channel
FRC97_RS18810	COG1511	domain protein
FRC97_RS18825	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FRC97_RS18835	COG1196	nuclear chromosome segregation
FRC97_RS18845	COG1742	UPF0060 membrane protein
FRC97_RS18855	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FRC97_RS18860	COG1132	(ABC) transporter
FRC97_RS18885	COG0789	Transcriptional regulator
FRC97_RS18890	COG0776	regulation of translation
FRC97_RS18895	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FRC97_RS18895	COG0072	phenylalanine-tRNA ligase activity
FRC97_RS18900	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FRC97_RS18905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FRC97_RS18910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FRC97_RS18915	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FRC97_RS18920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FRC97_RS18925	COG2224	Isocitrate lyase
FRC97_RS18940	COG1522	sequence-specific DNA binding
FRC97_RS18955	COG1840	ABC-type Fe3 transport system, periplasmic component
FRC97_RS18975	COG2153	protein acetylation
FRC97_RS18980	COG2130	NADP-dependent
FRC97_RS19000	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS19005	COG2050	protein possibly involved in aromatic compounds catabolism
FRC97_RS19010	COG0183	Belongs to the thiolase family
FRC97_RS19015	COG1024	Enoyl-CoA hydratase
FRC97_RS19015	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_RS19280	COG3706	GGDEF domain
FRC97_RS19305	COG0411	ABC transporter
FRC97_RS19315	COG0559	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS19325	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS19330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FRC97_RS19335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FRC97_RS19340	COG2917	probably involved in intracellular septation
FRC97_RS19350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FRC97_RS19370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FRC97_RS19375	COG0688	phosphatidylethanolamine metabolic process
FRC97_RS19390	COG5006	permease, DMT superfamily
FRC97_RS19405	COG1228	amidohydrolase
FRC97_RS19420	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FRC97_RS19425	COG2986	histidine ammonia-lyase
FRC97_RS19430	COG2188	Transcriptional regulator
FRC97_RS19440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS19450	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC97_RS19455	COG1366	Belongs to the anti-sigma-factor antagonist family
FRC97_RS19460	COG2172	sigma factor antagonist activity
FRC97_RS19470	COG2205	protein histidine kinase activity
FRC97_RS19475	COG2205	protein histidine kinase activity
FRC97_RS19480	COG0784	Response regulator, receiver
FRC97_RS19480	COG4191	Histidine kinase
FRC97_RS19500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FRC97_RS19520	COG0297	glycogen (starch) synthase activity
FRC97_RS19525	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS19530	COG0557	exoribonuclease II activity
FRC97_RS19555	COG0741	lytic transglycosylase activity
FRC97_RS19560	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FRC97_RS19565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FRC97_RS19575	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FRC97_RS19580	COG0517	IMP dehydrogenase activity
FRC97_RS19580	COG1125	glycine betaine transport
FRC97_RS19595	COG1011	Hydrolase
FRC97_RS19600	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FRC97_RS19605	COG5002	protein histidine kinase activity
FRC97_RS19655	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS19665	COG0642	Histidine kinase
FRC97_RS19680	COG0667	Aldo Keto reductase
FRC97_RS19685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FRC97_RS19690	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC97_RS19695	COG4181	ATPase activity
FRC97_RS19735	COG1054	Belongs to the UPF0176 family
FRC97_RS19740	COG1741	Belongs to the pirin family
FRC97_RS19750	COG1741	Belongs to the pirin family
FRC97_RS19755	COG0583	DNA-binding transcription factor activity
FRC97_RS19760	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
FRC97_RS19760	COG0493	'glutamate synthase
FRC97_RS19765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_RS19770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FRC97_RS19780	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FRC97_RS19805	COG0583	DNA-binding transcription factor activity
FRC97_RS19815	COG1116	anion transmembrane transporter activity
FRC97_RS19820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FRC97_RS19830	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FRC97_RS19840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FRC97_RS19850	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FRC97_RS19855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS19855	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FRC97_RS19870	COG0730	response to heat
FRC97_RS19885	COG0175	sulfate reduction
FRC97_RS19890	COG0529	Catalyzes the synthesis of activated sulfate
FRC97_RS19890	COG2895	sulfate adenylyltransferase (ATP) activity
FRC97_RS19895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FRC97_RS19900	COG0492	ferredoxin-NADP+ reductase activity
FRC97_RS19950	COG0351	phosphomethylpyrimidine kinase
FRC97_RS19965	COG2022	thiamine diphosphate biosynthetic process
FRC97_RS19980	COG1250	3-hydroxyacyl-CoA dehydrogenase
FRC97_RS19985	COG1024	Enoyl-CoA hydratase
FRC97_RS20000	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS20015	COG1619	proteins homologs of microcin C7 resistance protein MccF
FRC97_RS20040	COG0826	peptidase U32
FRC97_RS20055	COG1506	peptidase
FRC97_RS20055	COG4946	Tricorn protease homolog
FRC97_RS20055	COG0823	Involved in the tonB-independent uptake of proteins
FRC97_RS20065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FRC97_RS20070	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FRC97_RS20085	COG3047	cAMP biosynthetic process
FRC97_RS20090	COG2354	Protein conserved in bacteria
FRC97_RS20095	COG3300	MHYT domain
FRC97_RS20095	COG5001	Diguanylate cyclase
FRC97_RS20110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FRC97_RS20110	COG0047	phosphoribosylformylglycinamidine synthase activity
FRC97_RS20115	COG0024	Methionine aminopeptidase
FRC97_RS20120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FRC97_RS20125	COG0242	peptide deformylase activity
FRC97_RS20130	COG2832	Protein of unknown function (DUF454)
FRC97_RS20145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FRC97_RS20150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FRC97_RS20155	COG1414	Transcriptional regulator
FRC97_RS20165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FRC97_RS20170	COG1183	phosphatidylcholine synthase activity
FRC97_RS20175	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FRC97_RS20180	COG0440	acetolactate synthase activity
FRC97_RS20185	COG0028	Belongs to the TPP enzyme family
FRC97_RS20195	COG1595	DNA-templated transcription, initiation
FRC97_RS20215	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FRC97_RS20225	COG0347	Belongs to the P(II) protein family
FRC97_RS20240	COG0583	DNA-binding transcription factor activity
FRC97_RS20250	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS20255	COG0835	chemotaxis
FRC97_RS20280	COG1252	NADH dehydrogenase
FRC97_RS20290	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FRC97_RS20325	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS20345	COG4120	Belongs to the binding-protein-dependent transport system permease family
FRC97_RS20360	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FRC97_RS20365	COG0509	glycine decarboxylation via glycine cleavage system
FRC97_RS20370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC97_RS20370	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRC97_RS20375	COG0545	Peptidyl-prolyl cis-trans isomerase
FRC97_RS20385	COG0564	pseudouridine synthase activity
FRC97_RS20390	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS20415	COG0589	response to stress
FRC97_RS20455	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FRC97_RS20475	COG0583	DNA-binding transcription factor activity
FRC97_RS20480	COG0436	Aminotransferase
FRC97_RS20515	COG0683	leucine binding
FRC97_RS20525	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS20530	COG1024	Enoyl-CoA hydratase
FRC97_RS20540	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS20555	COG0596	Alpha beta hydrolase
FRC97_RS20560	COG2205	protein histidine kinase activity
FRC97_RS20570	COG3593	DNA synthesis involved in DNA repair
FRC97_RS20580	COG0210	DNA helicase
FRC97_RS20620	COG1530	ribonuclease E activity
FRC97_RS20625	COG0424	maF-like protein
FRC97_RS20635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FRC97_RS20640	COG0799	negative regulation of ribosome biogenesis
FRC97_RS20645	COG0408	coproporphyrinogen oxidase activity
FRC97_RS20650	COG0151	Belongs to the GarS family
FRC97_RS20655	COG0217	transcriptional regulatory protein
FRC97_RS20660	COG0433	COG0433 Predicted ATPase
FRC97_RS20680	COG0277	FAD linked oxidase domain protein
FRC97_RS20685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FRC97_RS20710	COG0625	glutathione transferase activity
FRC97_RS20725	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FRC97_RS20740	COG0402	S-adenosylhomocysteine deaminase activity
FRC97_RS20775	COG0484	heat shock protein binding
FRC97_RS20780	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_RS20800	COG3284	Transcriptional regulator
FRC97_RS20810	COG2925	Exonuclease
FRC97_RS20815	COG2951	lytic endotransglycosylase activity
FRC97_RS20820	COG0542	response to heat
FRC97_RS20825	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FRC97_RS20840	COG1199	ATP-dependent helicase activity
FRC97_RS20855	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FRC97_RS20860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FRC97_RS20865	COG0508	dehydrogenase complex catalyzes the overall conversion of
FRC97_RS20870	COG0567	Dehydrogenase, E1 component
FRC97_RS20875	COG0628	permease
FRC97_RS20880	COG3447	MASE1 domain protein
FRC97_RS20880	COG5001	Diguanylate cyclase
FRC97_RS20880	COG5002	protein histidine kinase activity
FRC97_RS20885	COG4172	Belongs to the ABC transporter superfamily
FRC97_RS20890	COG4239	(ABC) transporter, permease
FRC97_RS20895	COG4174	ABC transporter (Permease)
FRC97_RS20900	COG4166	transmembrane transport
FRC97_RS20910	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FRC97_RS21025	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FRC97_RS21040	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FRC97_RS21045	COG1605	Chorismate mutase
FRC97_RS21045	COG0077	Prephenate dehydratase
FRC97_RS21050	COG0287	Prephenate dehydrogenase
FRC97_RS21055	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FRC97_RS21065	COG0776	regulation of translation
FRC97_RS21075	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FRC97_RS21080	COG2111	Na H antiporter
FRC97_RS21080	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FRC97_RS21085	COG1006	Multisubunit Na H antiporter MnhC subunit
FRC97_RS21090	COG0651	ATP synthesis coupled electron transport
FRC97_RS21100	COG2212	antiporter activity
FRC97_RS21135	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FRC97_RS21160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FRC97_RS21165	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FRC97_RS21170	COG0405	Gamma-glutamyltransferase
FRC97_RS21210	COG3193	protein, possibly involved in utilization of glycolate and propanediol
FRC97_RS21215	COG0670	Belongs to the BI1 family
FRC97_RS21225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FRC97_RS21240	COG0506	proline dehydrogenase activity
FRC97_RS21240	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC97_RS21240	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FRC97_RS21250	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FRC97_RS21260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FRC97_RS21265	COG4774	siderophore transport
FRC97_RS21300	COG0494	nUDIX hydrolase
FRC97_RS21305	COG1278	Cold shock
FRC97_RS21320	COG0492	ferredoxin-NADP+ reductase activity
FRC97_RS21325	COG2226	methyltransferase
FRC97_RS21370	COG3209	COG3209 Rhs family protein
FRC97_RS21390	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS21400	COG0583	DNA-binding transcription factor activity
FRC97_RS21430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FRC97_RS21470	COG0582	viral genome integration into host DNA
FRC97_RS21475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FRC97_RS21475	COG0519	Catalyzes the synthesis of GMP from XMP
FRC97_RS21500	COG2914	Belongs to the UPF0125 (RnfH) family
FRC97_RS21510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FRC97_RS21530	COG1024	Enoyl-CoA hydratase
FRC97_RS21535	COG1253	flavin adenine dinucleotide binding
FRC97_RS21545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FRC97_RS21550	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FRC97_RS21555	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FRC97_RS21560	COG0195	Participates in both transcription termination and antitermination
FRC97_RS21565	COG0779	Required for maturation of 30S ribosomal subunits
FRC97_RS21575	COG2010	Cytochrome c
FRC97_RS21575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FRC97_RS21640	COG2423	ornithine cyclodeaminase activity
FRC97_RS21660	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FRC97_RS21670	COG2885	chlorophyll binding
FRC97_RS21675	COG0823	Involved in the tonB-independent uptake of proteins
FRC97_RS21680	COG1132	(ABC) transporter
FRC97_RS21690	COG0084	hydrolase, TatD family'
FRC97_RS21705	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FRC97_RS21710	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FRC97_RS21725	COG0657	acetylesterase activity
FRC97_RS21735	COG1454	alcohol dehydrogenase
FRC97_RS21750	COG2183	response to ionizing radiation
FRC97_RS21775	COG2814	Major facilitator Superfamily
FRC97_RS21780	COG2814	Major facilitator Superfamily
FRC97_RS21820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FRC97_RS21835	COG1286	toxin biosynthetic process
FRC97_RS21845	COG0285	dihydrofolate synthase activity
FRC97_RS21850	COG1393	Belongs to the ArsC family
FRC97_RS21860	COG3123	guanosine phosphorylase activity
FRC97_RS21865	COG0137	argininosuccinate synthase activity
FRC97_RS21875	COG1666	GTP binding
FRC97_RS21880	COG3577	Aspartyl protease
FRC97_RS21890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FRC97_RS21895	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FRC97_RS21900	COG0667	Aldo Keto reductase
FRC97_RS21905	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FRC97_RS21915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FRC97_RS21925	COG0308	aminopeptidase N
FRC97_RS21930	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FRC97_RS21940	COG0583	DNA-binding transcription factor activity
FRC97_RS21945	COG1960	acyl-CoA dehydrogenase activity
FRC97_RS21950	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS21955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FRC97_RS21960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FRC97_RS21965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FRC97_RS21970	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_RS21975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_RS21980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FRC97_RS21985	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FRC97_RS22000	COG0750	zinc metalloprotease
FRC97_RS22005	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FRC97_RS22010	COG0575	Belongs to the CDS family
FRC97_RS22020	COG0233	cytoplasmic translational termination
FRC97_RS22025	COG0528	UMP kinase activity
FRC97_RS22030	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FRC97_RS22035	COG0052	Belongs to the universal ribosomal protein uS2 family
FRC97_RS22040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FRC97_RS22045	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FRC97_RS22045	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FRC97_RS22070	COG0789	Transcriptional regulator
FRC97_RS22100	COG2132	Multicopper oxidase
FRC97_RS22130	COG3191	aminopeptidase activity
FRC97_RS22145	COG0488	(ABC) transporter
FRC97_RS22150	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FRC97_RS22155	COG0513	Belongs to the DEAD box helicase family
FRC97_RS22165	COG4651	solute:proton antiporter activity
FRC97_RS22165	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FRC97_RS22195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FRC97_RS22205	COG2207	Transcriptional regulator
FRC97_RS22210	COG1012	belongs to the aldehyde dehydrogenase family
FRC97_RS22250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FRC97_RS22260	COG2267	carboxylic ester hydrolase activity
FRC97_RS22280	COG1028	Short-chain dehydrogenase reductase Sdr
FRC97_RS22285	COG0028	Belongs to the TPP enzyme family
FRC97_RS22290	COG3181	Tripartite tricarboxylate transporter family receptor
FRC97_RS22300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FRC97_RS22500	COG3728	DNA packaging
FRC97_RS22500	COG5484	DNA packaging
FRC97_RS22535	COG1802	Transcriptional regulator
FRC97_RS22535	COG4626	Terminase
FRC97_RS22610	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FRC97_RS22625	COG0534	Mate efflux family protein
FRC97_RS22630	COG0318	PFAM AMP-dependent synthetase and ligase
FRC97_RS22660	COG2771	luxR family
FRC97_RS22665	COG3916	Acyl-homoserine-lactone synthase
FRC97_RS22675	COG1802	Transcriptional regulator
FRC97_RS22685	COG0154	amidase activity