locus-tag	class	description
H9L24_RS00035	COG0270	DNA (cytosine-5-)-methyltransferase activity
H9L24_RS00180	COG4695	Portal protein
H9L24_RS00205	COG2391	methyltransferase activity
H9L24_RS00225	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H9L24_RS00255	COG0737	Belongs to the 5'-nucleotidase family
H9L24_RS00265	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H9L24_RS00270	COG0642	Histidine kinase
H9L24_RS00390	COG1067	ATP-dependent peptidase activity
H9L24_RS00420	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
H9L24_RS00425	COG1562	ergosterol biosynthetic process
H9L24_RS00430	COG1760	l-serine dehydratase
H9L24_RS00460	COG0544	peptidyl-prolyl cis-trans isomerase activity
H9L24_RS00465	COG0740	serine-type endopeptidase activity
H9L24_RS00470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
H9L24_RS00475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9L24_RS00505	COG1451	nucleotide metabolic process
H9L24_RS00520	COG0114	fumarate hydratase activity
H9L24_RS00540	COG2113	Glycine betaine
H9L24_RS00545	COG4176	ABC-type proline glycine betaine transport system permease component
H9L24_RS00550	COG4175	Glycine betaine
H9L24_RS00560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L24_RS00570	COG4654	Cytochrome c, class I
H9L24_RS00580	COG0583	DNA-binding transcription factor activity
H9L24_RS00585	COG0129	dihydroxy-acid dehydratase activity
H9L24_RS00600	COG1802	Transcriptional regulator
H9L24_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS00710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L24_RS00735	COG0730	response to heat
H9L24_RS00750	COG4206	TonB-dependent receptor
H9L24_RS00770	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
H9L24_RS00780	COG1120	ATPase activity
H9L24_RS00800	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
H9L24_RS00815	COG0786	glutamate:sodium symporter activity
H9L24_RS00825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L24_RS00840	COG1492	cobalamin metabolic process
H9L24_RS00845	COG0778	Nitroreductase
H9L24_RS00850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H9L24_RS00865	COG3842	ATPase activity
H9L24_RS00875	COG1176	ABC-type spermidine putrescine transport system, permease component I
H9L24_RS00885	COG1802	Transcriptional regulator
H9L24_RS00895	COG0471	metal ion transport
H9L24_RS00900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H9L24_RS00910	COG0154	amidase activity
H9L24_RS00915	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS00925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS00930	COG2900	Belongs to the SlyX family
H9L24_RS00935	COG0513	Belongs to the DEAD box helicase family
H9L24_RS00940	COG0667	Aldo Keto reductase
H9L24_RS00950	COG3530	Putative quorum-sensing-regulated virulence factor
H9L24_RS00985	COG3842	ATPase activity
H9L24_RS00990	COG1840	ABC-type Fe3 transport system, periplasmic component
H9L24_RS00995	COG0583	DNA-binding transcription factor activity
H9L24_RS01010	COG0028	Belongs to the TPP enzyme family
H9L24_RS01020	COG0583	DNA-binding transcription factor activity
H9L24_RS01030	COG2766	serine protein kinase
H9L24_RS01050	COG0765	amino acid transport
H9L24_RS01055	COG0765	amino acid transport
H9L24_RS01070	COG0560	Phosphoserine phosphatase
H9L24_RS01090	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
H9L24_RS01090	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L24_RS01095	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
H9L24_RS01115	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS01125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L24_RS01140	COG0789	Transcriptional regulator
H9L24_RS01160	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
H9L24_RS01220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L24_RS01225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
H9L24_RS01240	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS01245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L24_RS01260	COG0322	excinuclease ABC activity
H9L24_RS01270	COG0776	regulation of translation
H9L24_RS01280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L24_RS01290	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H9L24_RS01295	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
H9L24_RS01315	COG0741	lytic transglycosylase activity
H9L24_RS01315	COG1388	LysM domain
H9L24_RS01320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L24_RS01325	COG2226	methyltransferase
H9L24_RS01330	COG0328	RNA-DNA hybrid ribonuclease activity
H9L24_RS01335	COG1566	PFAM secretion protein HlyD family protein
H9L24_RS01340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L24_RS01370	COG0746	molybdenum cofactor guanylyltransferase activity
H9L24_RS01405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9L24_RS01415	COG0840	transmembrane signaling receptor activity
H9L24_RS01440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H9L24_RS01475	COG0582	viral genome integration into host DNA
H9L24_RS01485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H9L24_RS01485	COG4651	solute:proton antiporter activity
H9L24_RS01490	COG0625	glutathione transferase activity
H9L24_RS01510	COG0488	(ABC) transporter
H9L24_RS01590	COG0789	Transcriptional regulator
H9L24_RS01625	COG3158	transport of potassium into the cell
H9L24_RS01635	COG0583	DNA-binding transcription factor activity
H9L24_RS01645	COG0667	Aldo Keto reductase
H9L24_RS01660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L24_RS01670	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L24_RS01680	COG0154	amidase activity
H9L24_RS01690	COG0747	negative chemotaxis
H9L24_RS01705	COG0747	negative chemotaxis
H9L24_RS01725	COG0840	transmembrane signaling receptor activity
H9L24_RS01745	COG2841	Protein conserved in bacteria
H9L24_RS01755	COG4166	transmembrane transport
H9L24_RS01775	COG4239	(ABC) transporter, permease
H9L24_RS01865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS01875	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9L24_RS01875	COG2010	Cytochrome c
H9L24_RS01885	COG0779	Required for maturation of 30S ribosomal subunits
H9L24_RS01890	COG0195	Participates in both transcription termination and antitermination
H9L24_RS01895	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
H9L24_RS01900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
H9L24_RS01905	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H9L24_RS01920	COG1024	Enoyl-CoA hydratase
H9L24_RS01940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
H9L24_RS01965	COG2914	Belongs to the UPF0125 (RnfH) family
H9L24_RS01990	COG0519	Catalyzes the synthesis of GMP from XMP
H9L24_RS01990	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H9L24_RS02005	COG1335	isochorismatase
H9L24_RS02025	COG0583	DNA-binding transcription factor activity
H9L24_RS02035	COG4221	oxidoreductase activity
H9L24_RS02040	COG0183	Belongs to the thiolase family
H9L24_RS02055	COG0330	HflC and HflK could
H9L24_RS02090	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H9L24_RS02095	COG0640	Transcriptional regulator
H9L24_RS02115	COG0506	proline dehydrogenase activity
H9L24_RS02115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H9L24_RS02115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H9L24_RS02130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
H9L24_RS02140	COG0670	Belongs to the BI1 family
H9L24_RS02145	COG3193	protein, possibly involved in utilization of glycolate and propanediol
H9L24_RS02200	COG1522	sequence-specific DNA binding
H9L24_RS02205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L24_RS02225	COG0251	oxidation-reduction process
H9L24_RS02245	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
H9L24_RS02250	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H9L24_RS02255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
H9L24_RS02260	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
H9L24_RS02265	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
H9L24_RS02270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L24_RS02270	COG0072	phenylalanine-tRNA ligase activity
H9L24_RS02275	COG0776	regulation of translation
H9L24_RS02280	COG0789	Transcriptional regulator
H9L24_RS02290	COG2202	Pas domain
H9L24_RS02290	COG2205	protein histidine kinase activity
H9L24_RS02330	COG3474	cytochrome
H9L24_RS02350	COG0583	DNA-binding transcription factor activity
H9L24_RS02355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L24_RS02360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS02365	COG3850	Histidine kinase
H9L24_RS02365	COG3437	response regulator, receiver
H9L24_RS02365	COG2205	protein histidine kinase activity
H9L24_RS02365	COG4999	Histidine kinase
H9L24_RS02375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H9L24_RS02380	COG3177	Filamentation induced by cAMP protein fic
H9L24_RS02390	COG1116	anion transmembrane transporter activity
H9L24_RS02415	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H9L24_RS02445	COG2267	carboxylic ester hydrolase activity
H9L24_RS02470	COG0667	Aldo Keto reductase
H9L24_RS02475	COG3655	Transcriptional regulator
H9L24_RS02490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
H9L24_RS02500	COG3577	Aspartyl protease
H9L24_RS02505	COG1666	GTP binding
H9L24_RS02510	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H9L24_RS02525	COG0583	DNA-binding transcription factor activity
H9L24_RS02530	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L24_RS02535	COG1595	DNA-templated transcription, initiation
H9L24_RS02540	COG0137	argininosuccinate synthase activity
H9L24_RS02545	COG3123	guanosine phosphorylase activity
H9L24_RS02555	COG1393	Belongs to the ArsC family
H9L24_RS02560	COG0285	dihydrofolate synthase activity
H9L24_RS02585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L24_RS02625	COG0583	DNA-binding transcription factor activity
H9L24_RS02635	COG0583	DNA-binding transcription factor activity
H9L24_RS02645	COG2814	Major facilitator Superfamily
H9L24_RS02665	COG2855	membrane
H9L24_RS02690	COG0242	peptide deformylase activity
H9L24_RS02705	COG5002	protein histidine kinase activity
H9L24_RS02720	COG0047	phosphoribosylformylglycinamidine synthase activity
H9L24_RS02720	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H9L24_RS02725	COG2354	Protein conserved in bacteria
H9L24_RS02730	COG3047	cAMP biosynthetic process
H9L24_RS02735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L24_RS02765	COG0826	peptidase U32
H9L24_RS02780	COG1619	proteins homologs of microcin C7 resistance protein MccF
H9L24_RS02820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L24_RS02825	COG1024	Enoyl-CoA hydratase
H9L24_RS02830	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L24_RS02845	COG2022	thiamine diphosphate biosynthetic process
H9L24_RS02865	COG3209	COG3209 Rhs family protein
H9L24_RS02875	COG3209	COG3209 Rhs family protein
H9L24_RS02895	COG3209	COG3209 Rhs family protein
H9L24_RS02905	COG3209	COG3209 Rhs family protein
H9L24_RS02920	COG3209	COG3209 Rhs family protein
H9L24_RS02930	COG3209	COG3209 Rhs family protein
H9L24_RS02940	COG3209	COG3209 Rhs family protein
H9L24_RS02955	COG0351	phosphomethylpyrimidine kinase
H9L24_RS02965	COG0492	ferredoxin-NADP+ reductase activity
H9L24_RS02970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H9L24_RS02975	COG2895	sulfate adenylyltransferase (ATP) activity
H9L24_RS02975	COG0529	Catalyzes the synthesis of activated sulfate
H9L24_RS02980	COG0175	sulfate reduction
H9L24_RS02985	COG0175	sulfate reduction
H9L24_RS02995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L24_RS03000	COG0730	response to heat
H9L24_RS03015	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
H9L24_RS03025	COG0431	NADPH-dependent FMN reductase
H9L24_RS03035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L24_RS03040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L24_RS03045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L24_RS03050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9L24_RS03055	COG1116	anion transmembrane transporter activity
H9L24_RS03070	COG0583	DNA-binding transcription factor activity
H9L24_RS03095	COG1309	transcriptional regulator
H9L24_RS03115	COG2188	Transcriptional regulator
H9L24_RS03120	COG2986	histidine ammonia-lyase
H9L24_RS03125	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
H9L24_RS03135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS03140	COG0765	amino acid transport
H9L24_RS03160	COG1228	amidohydrolase
H9L24_RS03170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L24_RS03215	COG1280	lysine exporter protein (LysE YggA)
H9L24_RS03230	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
H9L24_RS03240	COG0835	chemotaxis
H9L24_RS03255	COG3706	GGDEF domain
H9L24_RS03275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L24_RS03285	COG2917	probably involved in intracellular septation
H9L24_RS03290	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L24_RS03295	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H9L24_RS03300	COG2207	Transcriptional regulator
H9L24_RS03310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L24_RS03325	COG0559	Belongs to the binding-protein-dependent transport system permease family
H9L24_RS03335	COG0411	ABC transporter
H9L24_RS03350	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L24_RS03350	COG1024	Enoyl-CoA hydratase
H9L24_RS03355	COG0183	Belongs to the thiolase family
H9L24_RS03375	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS03385	COG2130	NADP-dependent
H9L24_RS03405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L24_RS03415	COG2814	Major facilitator Superfamily
H9L24_RS03435	COG2197	response regulator
H9L24_RS03495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H9L24_RS03500	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
H9L24_RS03505	COG0470	DNA polymerase III
H9L24_RS03515	COG0084	hydrolase, TatD family'
H9L24_RS03525	COG1132	(ABC) transporter
H9L24_RS03535	COG2885	chlorophyll binding
H9L24_RS03545	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H9L24_RS03565	COG2226	methyltransferase
H9L24_RS03570	COG1215	transferase activity, transferring glycosyl groups
H9L24_RS03590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9L24_RS03595	COG0300	oxidoreductase activity
H9L24_RS03615	COG0567	Dehydrogenase, E1 component
H9L24_RS03620	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L24_RS03625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L24_RS03645	COG1199	ATP-dependent helicase activity
H9L24_RS03660	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H9L24_RS03665	COG0542	response to heat
H9L24_RS03675	COG2951	lytic endotransglycosylase activity
H9L24_RS03680	COG2925	Exonuclease
H9L24_RS03685	COG0745	RESPONSE REGULATOR receiver
H9L24_RS03690	COG2205	protein histidine kinase activity
H9L24_RS03695	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H9L24_RS03700	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H9L24_RS03720	COG0217	transcriptional regulatory protein
H9L24_RS03775	COG0433	COG0433 Predicted ATPase
H9L24_RS03780	COG0217	transcriptional regulatory protein
H9L24_RS03795	COG0799	negative regulation of ribosome biogenesis
H9L24_RS03800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
H9L24_RS03805	COG0424	maF-like protein
H9L24_RS03810	COG1530	ribonuclease E activity
H9L24_RS03815	COG0582	viral genome integration into host DNA
H9L24_RS03825	COG1396	sequence-specific DNA binding
H9L24_RS03830	COG3550	peptidyl-serine autophosphorylation
H9L24_RS03905	COG4191	Histidine kinase
H9L24_RS03910	COG0436	Aminotransferase
H9L24_RS03915	COG0583	DNA-binding transcription factor activity
H9L24_RS03935	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
H9L24_RS03965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H9L24_RS03970	COG0252	asparaginase activity
H9L24_RS03975	COG1473	amidohydrolase
H9L24_RS03980	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS04030	COG0583	DNA-binding transcription factor activity
H9L24_RS04035	COG0590	tRNA wobble adenosine to inosine editing
H9L24_RS04040	COG2807	transmembrane transport
H9L24_RS04050	COG1902	pentaerythritol trinitrate reductase activity
H9L24_RS04055	COG0697	spore germination
H9L24_RS04090	COG1053	succinate dehydrogenase
H9L24_RS04100	COG0133	tryptophan synthase activity
H9L24_RS04115	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS04160	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
H9L24_RS04165	COG0583	DNA-binding transcription factor activity
H9L24_RS04175	COG1132	(ABC) transporter
H9L24_RS04230	COG1607	acyl-coa hydrolase
H9L24_RS04235	COG3800	Transcriptional regulator
H9L24_RS04235	COG1396	sequence-specific DNA binding
H9L24_RS04245	COG1742	UPF0060 membrane protein
H9L24_RS04250	COG1196	nuclear chromosome segregation
H9L24_RS04260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H9L24_RS04315	COG0183	Belongs to the thiolase family
H9L24_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS04325	COG0488	(ABC) transporter
H9L24_RS04345	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L24_RS04350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L24_RS04360	COG2171	N-acyltransferase activity
H9L24_RS04370	COG0840	transmembrane signaling receptor activity
H9L24_RS04375	COG2878	Part of a membrane complex involved in electron transport
H9L24_RS04410	COG1022	Amp-dependent synthetase and ligase
H9L24_RS04420	COG1802	Transcriptional regulator
H9L24_RS04430	COG1703	isobutyryl-CoA mutase activity
H9L24_RS04445	COG4770	biotin carboxylase activity
H9L24_RS04480	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L24_RS04490	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H9L24_RS04520	COG0642	Histidine kinase
H9L24_RS04530	COG2205	protein histidine kinase activity
H9L24_RS04530	COG2202	Pas domain
H9L24_RS04540	COG0784	Response regulator, receiver
H9L24_RS04550	COG5001	Diguanylate cyclase
H9L24_RS04550	COG3300	MHYT domain
H9L24_RS04555	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS04595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L24_RS04600	COG0583	DNA-binding transcription factor activity
H9L24_RS04605	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L24_RS04605	COG1024	Enoyl-CoA hydratase
H9L24_RS04610	COG0183	Belongs to the thiolase family
H9L24_RS04615	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS04620	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS04625	COG1024	Enoyl-CoA hydratase
H9L24_RS04630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS04635	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS04665	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS04695	COG1380	Effector of murein hydrolase LrgA
H9L24_RS04710	COG0784	Response regulator, receiver
H9L24_RS04710	COG5002	protein histidine kinase activity
H9L24_RS04710	COG2198	Histidine kinase
H9L24_RS04715	COG0417	DNA replication proofreading
H9L24_RS04725	COG0024	Methionine aminopeptidase
H9L24_RS04730	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS04740	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS04760	COG0346	lactoylglutathione lyase activity
H9L24_RS04775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H9L24_RS04780	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L24_RS04800	COG0800	Aldolase
H9L24_RS04810	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS04815	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L24_RS04820	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L24_RS04825	COG3265	gluconokinase activity
H9L24_RS04830	COG1609	Transcriptional regulator
H9L24_RS04865	COG1309	transcriptional regulator
H9L24_RS04870	COG0259	pyridoxamine-phosphate oxidase activity
H9L24_RS04900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
H9L24_RS04920	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H9L24_RS04930	COG1538	Outer membrane efflux protein
H9L24_RS04990	COG3718	enzyme involved in inositol metabolism
H9L24_RS05005	COG4948	Mandelate Racemase Muconate Lactonizing
H9L24_RS05010	COG2271	Major facilitator Superfamily
H9L24_RS05015	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS05020	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9L24_RS05025	COG0583	DNA-binding transcription factor activity
H9L24_RS05030	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
H9L24_RS05060	COG0840	transmembrane signaling receptor activity
H9L24_RS05070	COG2133	pyrroloquinoline quinone binding
H9L24_RS05075	COG0791	NLP P60 protein
H9L24_RS05125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
H9L24_RS05135	COG0583	DNA-binding transcription factor activity
H9L24_RS05140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H9L24_RS05145	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L24_RS05150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
H9L24_RS05160	COG4566	intracellular signal transduction
H9L24_RS05165	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H9L24_RS05180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
H9L24_RS05185	COG0167	dihydroorotate dehydrogenase activity
H9L24_RS05205	COG0579	oxidoreductase
H9L24_RS05230	COG0633	Ferredoxin
H9L24_RS05235	COG0443	Heat shock 70 kDa protein
H9L24_RS05240	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
H9L24_RS05250	COG0822	iron-sulfur transferase activity
H9L24_RS05255	COG1104	cysteine desulfurase activity
H9L24_RS05260	COG1959	2 iron, 2 sulfur cluster binding
H9L24_RS05265	COG0556	nucleotide-excision repair
H9L24_RS05280	COG3384	dioxygenase
H9L24_RS05335	COG0456	acetyltransferase
H9L24_RS05335	COG1846	Transcriptional regulator
H9L24_RS05345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L24_RS05355	COG1595	DNA-templated transcription, initiation
H9L24_RS05360	COG0543	2 iron, 2 sulfur cluster binding
H9L24_RS05360	COG0633	Ferredoxin
H9L24_RS05385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H9L24_RS05390	COG1570	exodeoxyribonuclease VII activity
H9L24_RS05400	COG0848	biopolymer transport protein
H9L24_RS05405	COG1663	tetraacyldisaccharide 4'-kinase activity
H9L24_RS05410	COG2835	tetraacyldisaccharide 4'-kinase activity
H9L24_RS05415	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
H9L24_RS05420	COG0563	adenylate kinase activity
H9L24_RS05430	COG1739	Uncharacterized protein family UPF0029
H9L24_RS05445	COG3550	peptidyl-serine autophosphorylation
H9L24_RS05460	COG0765	amino acid transport
H9L24_RS05465	COG0501	Belongs to the peptidase M48B family
H9L24_RS05480	COG0179	Fumarylacetoacetate (FAA) hydrolase
H9L24_RS05485	COG0693	protein deglycase activity
H9L24_RS05515	COG0583	DNA-binding transcription factor activity
H9L24_RS05525	COG0667	Aldo Keto reductase
H9L24_RS05530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H9L24_RS05535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L24_RS05540	COG4181	ATPase activity
H9L24_RS05585	COG1054	Belongs to the UPF0176 family
H9L24_RS05590	COG1741	Belongs to the pirin family
H9L24_RS05600	COG2259	Doxx family
H9L24_RS05605	COG1741	Belongs to the pirin family
H9L24_RS05610	COG0583	DNA-binding transcription factor activity
H9L24_RS05625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H9L24_RS05655	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L24_RS05670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS05680	COG1802	Transcriptional regulator
H9L24_RS05735	COG2814	Major facilitator Superfamily
H9L24_RS05750	COG1473	amidohydrolase
H9L24_RS05755	COG0564	pseudouridine synthase activity
H9L24_RS05775	COG0587	DNA-directed DNA polymerase activity
H9L24_RS05790	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
H9L24_RS05795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H9L24_RS05835	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9L24_RS05840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L24_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS05900	COG4120	Belongs to the binding-protein-dependent transport system permease family
H9L24_RS05905	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
H9L24_RS05910	COG0833	amino acid
H9L24_RS05925	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H9L24_RS05935	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L24_RS05935	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H9L24_RS05940	COG0545	Peptidyl-prolyl cis-trans isomerase
H9L24_RS05945	COG0789	Transcriptional regulator
H9L24_RS05960	COG0564	pseudouridine synthase activity
H9L24_RS05965	COG0697	spore germination
H9L24_RS05970	COG1846	Transcriptional regulator
H9L24_RS05975	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS05980	COG0183	Belongs to the thiolase family
H9L24_RS05990	COG2703	oxygen carrier activity
H9L24_RS05995	COG0589	response to stress
H9L24_RS06005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L24_RS06010	COG1414	Transcriptional regulator
H9L24_RS06015	COG0583	DNA-binding transcription factor activity
H9L24_RS06040	COG2188	Transcriptional regulator
H9L24_RS06055	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H9L24_RS06070	COG0667	Aldo Keto reductase
H9L24_RS06105	COG2159	amidohydrolase
H9L24_RS06135	COG1752	Esterase of the alpha-beta hydrolase superfamily
H9L24_RS06175	COG1396	sequence-specific DNA binding
H9L24_RS06195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L24_RS06225	COG1054	Belongs to the UPF0176 family
H9L24_RS06235	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
H9L24_RS06240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H9L24_RS06250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H9L24_RS06255	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H9L24_RS06265	COG0450	alkyl hydroperoxide reductase
H9L24_RS06280	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H9L24_RS06320	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H9L24_RS06335	COG1045	serine acetyltransferase
H9L24_RS06350	COG2011	ABC-type metal ion transport system permease component
H9L24_RS06375	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
H9L24_RS06380	COG1464	Belongs to the NlpA lipoprotein family
H9L24_RS06385	COG2011	ABC-type metal ion transport system permease component
H9L24_RS06390	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H9L24_RS06400	COG0840	transmembrane signaling receptor activity
H9L24_RS06410	COG0745	RESPONSE REGULATOR receiver
H9L24_RS06425	COG1012	belongs to the aldehyde dehydrogenase family
H9L24_RS06430	COG3284	Transcriptional regulator
H9L24_RS06435	COG2916	Histone family protein nucleoid-structuring protein H-NS
H9L24_RS06450	COG1252	NADH dehydrogenase
H9L24_RS06470	COG2855	membrane
H9L24_RS06490	COG3246	L-lysine catabolic process to acetate
H9L24_RS06495	COG2175	clavaminate synthase activity
H9L24_RS06500	COG2207	Transcriptional regulator
H9L24_RS06510	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS06530	COG1309	transcriptional regulator
H9L24_RS06535	COG0583	DNA-binding transcription factor activity
H9L24_RS06580	COG4628	conserved protein (DUF2132)
H9L24_RS06585	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9L24_RS06585	COG2010	Cytochrome c
H9L24_RS06590	COG2197	response regulator
H9L24_RS06610	COG0583	DNA-binding transcription factor activity
H9L24_RS06630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L24_RS06655	COG0277	FAD linked oxidase domain protein
H9L24_RS06665	COG3284	Transcriptional regulator
H9L24_RS06670	COG3199	ATP-NAD kinase
H9L24_RS06695	COG0508	dehydrogenase complex catalyzes the overall conversion of
H9L24_RS06705	COG0022	dehydrogenase e1 component
H9L24_RS06710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H9L24_RS06720	COG0735	belongs to the Fur family
H9L24_RS06730	COG0523	cobalamin synthesis protein
H9L24_RS06735	COG0803	Belongs to the bacterial solute-binding protein 9 family
H9L24_RS06750	COG0523	cobalamin synthesis protein
H9L24_RS06770	COG0724	RNA recognition motif
H9L24_RS06835	COG0582	viral genome integration into host DNA
H9L24_RS06850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H9L24_RS06865	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H9L24_RS06870	COG1605	Chorismate mutase
H9L24_RS06870	COG0077	Prephenate dehydratase
H9L24_RS06875	COG0287	Prephenate dehydrogenase
H9L24_RS06880	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H9L24_RS06890	COG0776	regulation of translation
H9L24_RS06900	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
H9L24_RS06910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H9L24_RS06910	COG2111	Na H antiporter
H9L24_RS06915	COG1006	Multisubunit Na H antiporter MnhC subunit
H9L24_RS06920	COG0651	ATP synthesis coupled electron transport
H9L24_RS06930	COG2212	antiporter activity
H9L24_RS06965	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
H9L24_RS06970	COG0681	Belongs to the peptidase S26 family
H9L24_RS07000	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
H9L24_RS07010	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L24_RS07020	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H9L24_RS07025	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
H9L24_RS07030	COG1414	Transcriptional regulator
H9L24_RS07040	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L24_RS07045	COG1183	phosphatidylcholine synthase activity
H9L24_RS07050	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
H9L24_RS07055	COG0440	acetolactate synthase activity
H9L24_RS07085	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
H9L24_RS07095	COG0347	Belongs to the P(II) protein family
H9L24_RS07100	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H9L24_RS07100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L24_RS07105	COG1492	cobalamin metabolic process
H9L24_RS07110	COG0840	transmembrane signaling receptor activity
H9L24_RS07115	COG0840	transmembrane signaling receptor activity
H9L24_RS07120	COG0835	chemotaxis
H9L24_RS07150	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
H9L24_RS07165	COG0583	DNA-binding transcription factor activity
H9L24_RS07275	COG1074	ATP-dependent DNA helicase activity
H9L24_RS07290	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
H9L24_RS07295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS07300	COG0372	Belongs to the citrate synthase family
H9L24_RS07305	COG0254	rRNA binding
H9L24_RS07315	COG0534	Mate efflux family protein
H9L24_RS07325	COG0745	RESPONSE REGULATOR receiver
H9L24_RS07330	COG0704	Plays a role in the regulation of phosphate uptake
H9L24_RS07335	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H9L24_RS07340	COG0581	inorganic phosphate transmembrane transporter activity
H9L24_RS07345	COG0573	inorganic phosphate transmembrane transporter activity
H9L24_RS07350	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H9L24_RS07365	COG0248	Ppx GppA phosphatase
H9L24_RS07400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H9L24_RS07415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
H9L24_RS07420	COG1534	Rna-binding protein
H9L24_RS07435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L24_RS07450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H9L24_RS07455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H9L24_RS07460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L24_RS07465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L24_RS07470	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L24_RS07475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L24_RS07490	COG0750	zinc metalloprotease
H9L24_RS07495	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
H9L24_RS07505	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H9L24_RS07510	COG0233	cytoplasmic translational termination
H9L24_RS07515	COG0528	UMP kinase activity
H9L24_RS07520	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
H9L24_RS07525	COG0052	Belongs to the universal ribosomal protein uS2 family
H9L24_RS07540	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H9L24_RS07540	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H9L24_RS07580	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
H9L24_RS07585	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9L24_RS07600	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
H9L24_RS07605	COG2200	EAL domain
H9L24_RS07605	COG2199	diguanylate cyclase activity
H9L24_RS07605	COG2202	Pas domain
H9L24_RS07630	COG1309	transcriptional regulator
H9L24_RS07640	COG1295	ribonuclease BN
H9L24_RS07650	COG0277	FAD linked oxidase domain protein
H9L24_RS07660	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
H9L24_RS07690	COG0798	PFAM Bile acid sodium symporter
H9L24_RS07695	COG0708	Exodeoxyribonuclease III
H9L24_RS07700	COG2204	response regulator
H9L24_RS07705	COG3852	Histidine kinase
H9L24_RS07715	COG0174	glutamine synthetase
H9L24_RS07775	COG0583	DNA-binding transcription factor activity
H9L24_RS07795	COG1024	Enoyl-CoA hydratase
H9L24_RS07805	COG0183	Belongs to the thiolase family
H9L24_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS07815	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
H9L24_RS07820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H9L24_RS07825	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
H9L24_RS07830	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
H9L24_RS07835	COG0330	HflC and HflK could
H9L24_RS07845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H9L24_RS07850	COG1923	regulation of RNA biosynthetic process
H9L24_RS07860	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L24_RS07870	COG0124	histidyl-tRNA synthetase
H9L24_RS07875	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
H9L24_RS07890	COG0820	rRNA (adenine-C2-)-methyltransferase activity
H9L24_RS07895	COG0105	UTP biosynthetic process
H9L24_RS07925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H9L24_RS07940	COG3540	Alkaline phosphatase
H9L24_RS07945	COG0662	Cupin 2, conserved barrel domain protein
H9L24_RS07960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H9L24_RS07980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS07985	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L24_RS08020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H9L24_RS08045	COG4558	Periplasmic binding protein
H9L24_RS08050	COG3720	iron ion transport
H9L24_RS08060	COG4771	TonB-dependent receptor
H9L24_RS08115	COG4774	siderophore transport
H9L24_RS08140	COG0657	acetylesterase activity
H9L24_RS08150	COG0028	Belongs to the TPP enzyme family
H9L24_RS08160	COG1522	sequence-specific DNA binding
H9L24_RS08170	COG1522	sequence-specific DNA binding
H9L24_RS08185	COG3384	dioxygenase
H9L24_RS08200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H9L24_RS08210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H9L24_RS08265	COG1525	nuclease
H9L24_RS08290	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS08300	COG0559	Belongs to the binding-protein-dependent transport system permease family
H9L24_RS08320	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS08325	COG1053	succinate dehydrogenase
H9L24_RS08330	COG0625	glutathione transferase activity
H9L24_RS08335	COG0564	pseudouridine synthase activity
H9L24_RS08360	COG2814	Major facilitator Superfamily
H9L24_RS08365	COG2988	succinylglutamate desuccinylase activity
H9L24_RS08430	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
H9L24_RS08435	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L24_RS08440	COG0436	Aminotransferase
H9L24_RS08445	COG0824	Thioesterase
H9L24_RS08465	COG0477	Major facilitator Superfamily
H9L24_RS08475	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H9L24_RS08480	COG1845	cytochrome c oxidase, subunit III
H9L24_RS08485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H9L24_RS08500	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
H9L24_RS08515	COG0826	peptidase U32
H9L24_RS08555	COG4106	trans-aconitate 2-methyltransferase activity
H9L24_RS08560	COG0039	L-malate dehydrogenase activity
H9L24_RS08565	COG2188	Transcriptional regulator
H9L24_RS08570	COG2009	succinate dehydrogenase
H9L24_RS08580	COG1053	succinate dehydrogenase
H9L24_RS08585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H9L24_RS08590	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H9L24_RS08600	COG4977	sequence-specific DNA binding
H9L24_RS08605	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H9L24_RS08610	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H9L24_RS08620	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS08655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H9L24_RS08660	COG1538	Outer membrane efflux protein
H9L24_RS08690	COG2308	Evidence 4 Homologs of previously reported genes of
H9L24_RS08715	COG0741	lytic transglycosylase activity
H9L24_RS08745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H9L24_RS08750	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
H9L24_RS08760	COG2850	peptidyl-arginine hydroxylation
H9L24_RS08775	COG0756	dUTP diphosphatase activity
H9L24_RS08785	COG0504	CTP synthase activity
H9L24_RS08790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
H9L24_RS08800	COG0148	phosphopyruvate hydratase activity
H9L24_RS08805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H9L24_RS08830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS08845	COG2833	Protein of unknown function (DUF455)
H9L24_RS08850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9L24_RS08855	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
H9L24_RS08870	COG4974	Belongs to the 'phage' integrase family
H9L24_RS08875	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS08890	COG2201	protein-glutamate methylesterase activity
H9L24_RS08895	COG4191	Histidine kinase
H9L24_RS08905	COG0802	atpase or kinase
H9L24_RS08910	COG0860	N-Acetylmuramoyl-L-alanine amidase
H9L24_RS08930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H9L24_RS08935	COG0584	glycerophosphoryl diester phosphodiesterase
H9L24_RS08940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9L24_RS08965	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
H9L24_RS08970	COG1136	(ABC) transporter
H9L24_RS08975	COG0071	Belongs to the small heat shock protein (HSP20) family
H9L24_RS08980	COG0668	transmembrane transport
H9L24_RS08985	COG0577	efflux transmembrane transporter activity
H9L24_RS09060	COG1007	ATP synthesis coupled electron transport
H9L24_RS09075	COG0713	ATP synthesis coupled electron transport
H9L24_RS09085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L24_RS09090	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
H9L24_RS09095	COG1034	ATP synthesis coupled electron transport
H9L24_RS09110	COG0649	NAD binding
H9L24_RS09115	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L24_RS09120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L24_RS09125	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H9L24_RS09140	COG0149	triose-phosphate isomerase activity
H9L24_RS09150	COG1185	polyribonucleotide nucleotidyltransferase activity
H9L24_RS09155	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
H9L24_RS09160	COG0436	Aminotransferase
H9L24_RS09200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L24_RS09200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H9L24_RS09210	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
H9L24_RS09215	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L24_RS09245	COG2197	response regulator
H9L24_RS09250	COG2205	protein histidine kinase activity
H9L24_RS09250	COG2198	Histidine kinase
H9L24_RS09250	COG0784	Response regulator, receiver
H9L24_RS09255	COG1012	belongs to the aldehyde dehydrogenase family
H9L24_RS09265	COG0542	response to heat
H9L24_RS09275	COG0314	molybdopterin synthase activity
H9L24_RS09305	COG0303	'Molybdopterin
H9L24_RS09310	COG1763	Mo-molybdopterin cofactor biosynthetic process
H9L24_RS09330	COG0436	Aminotransferase
H9L24_RS09340	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H9L24_RS09345	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
H9L24_RS09360	COG0305	Participates in initiation and elongation during chromosome replication
H9L24_RS09365	COG0359	binds to the 23S rRNA
H9L24_RS09370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
H9L24_RS09375	COG2965	DNA replication, synthesis of RNA primer
H9L24_RS09380	COG0360	Binds together with S18 to 16S ribosomal RNA
H9L24_RS09385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H9L24_RS09390	COG0443	Heat shock 70 kDa protein
H9L24_RS09400	COG0741	lytic transglycosylase activity
H9L24_RS09425	COG0066	3-isopropylmalate dehydratase activity
H9L24_RS09430	COG0473	3-isopropylmalate dehydrogenase activity
H9L24_RS09440	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
H9L24_RS09450	COG0101	tRNA pseudouridine synthase activity
H9L24_RS09455	COG0135	phosphoribosylanthranilate isomerase activity
H9L24_RS09460	COG0133	tryptophan synthase activity
H9L24_RS09465	COG0159	tryptophan synthase activity
H9L24_RS09470	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
H9L24_RS09475	COG0762	integral membrane protein
H9L24_RS09490	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H9L24_RS09515	COG1088	dTDP-glucose 4,6-dehydratase activity
H9L24_RS09520	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9L24_RS09555	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H9L24_RS09565	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H9L24_RS09570	COG0745	RESPONSE REGULATOR receiver
H9L24_RS09580	COG1472	Belongs to the glycosyl hydrolase 3 family
H9L24_RS09585	COG0736	holo-[acyl-carrier-protein] synthase activity
H9L24_RS09590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H9L24_RS09595	COG1381	Involved in DNA repair and RecF pathway recombination
H9L24_RS09600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H9L24_RS09605	COG0571	ribonuclease III activity
H9L24_RS09620	COG0481	GTPase activity
H9L24_RS09625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L24_RS09650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9L24_RS09655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L24_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS09670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
H9L24_RS09675	COG0416	fatty acid biosynthetic process
H9L24_RS09680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
H9L24_RS09685	COG1399	metal-binding, possibly nucleic acid-binding protein
H9L24_RS09690	COG0424	maF-like protein
H9L24_RS09730	COG3022	response to hydroperoxide
H9L24_RS09740	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L24_RS09740	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
H9L24_RS09750	COG0840	transmembrane signaling receptor activity
H9L24_RS09755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H9L24_RS09770	COG1304	FMN binding
H9L24_RS09780	COG2252	PERMEase
H9L24_RS09785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9L24_RS09795	COG2885	chlorophyll binding
H9L24_RS09830	COG0563	adenylate kinase activity
H9L24_RS09835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H9L24_RS09890	COG2207	Transcriptional regulator
H9L24_RS09925	COG0251	oxidation-reduction process
H9L24_RS09945	COG0412	Dienelactone hydrolase
H9L24_RS09970	COG1090	epimerase
H9L24_RS09990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS09995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L24_RS10005	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS10020	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L24_RS10020	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H9L24_RS10030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9L24_RS10075	COG0210	DNA helicase
H9L24_RS10085	COG0516	GMP reductase activity
H9L24_RS10095	COG2084	Dehydrogenase
H9L24_RS10115	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
H9L24_RS10120	COG0457	Tetratricopeptide repeat
H9L24_RS10140	COG1215	transferase activity, transferring glycosyl groups
H9L24_RS10145	COG2194	sulfuric ester hydrolase activity
H9L24_RS10150	COG2814	Major facilitator Superfamily
H9L24_RS10155	COG5001	Diguanylate cyclase
H9L24_RS10155	COG3300	MHYT domain
H9L24_RS10160	COG0513	Belongs to the DEAD box helicase family
H9L24_RS10170	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H9L24_RS10180	COG2154	pterin-4-alpha-carbinolamine dehydratase
H9L24_RS10185	COG1162	GTPase activity
H9L24_RS10190	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
H9L24_RS10195	COG0494	nUDIX hydrolase
H9L24_RS10200	COG0335	large ribosomal subunit rRNA binding
H9L24_RS10205	COG0336	Belongs to the RNA methyltransferase TrmD family
H9L24_RS10210	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H9L24_RS10215	COG0228	four-way junction DNA binding
H9L24_RS10235	COG1392	Phosphate transport regulator
H9L24_RS10260	COG0559	Belongs to the binding-protein-dependent transport system permease family
H9L24_RS10265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H9L24_RS10290	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H9L24_RS10295	COG1674	ftsk spoiiie
H9L24_RS10305	COG0492	ferredoxin-NADP+ reductase activity
H9L24_RS10310	COG0227	Belongs to the bacterial ribosomal protein bL28 family
H9L24_RS10315	COG0267	Belongs to the bacterial ribosomal protein bL33 family
H9L24_RS10320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS10335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
H9L24_RS10335	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
H9L24_RS10350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H9L24_RS10355	COG3132	Protein of unknown function, DUF480
H9L24_RS10360	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS10365	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS10380	COG2271	Major facilitator Superfamily
H9L24_RS10390	COG2351	hydroxyisourate hydrolase activity
H9L24_RS10395	COG0590	tRNA wobble adenosine to inosine editing
H9L24_RS10410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS10430	COG2205	protein histidine kinase activity
H9L24_RS10445	COG0196	riboflavin kinase activity
H9L24_RS10455	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
H9L24_RS10470	COG4149	molybdate abc transporter
H9L24_RS10475	COG1177	transmembrane transport
H9L24_RS10485	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H9L24_RS10500	COG0583	DNA-binding transcription factor activity
H9L24_RS10515	COG0697	spore germination
H9L24_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS10585	COG1136	(ABC) transporter
H9L24_RS10590	COG4591	ABC-type transport system involved in lipoprotein release permease component
H9L24_RS10600	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H9L24_RS10605	COG1942	4-Oxalocrotonate Tautomerase
H9L24_RS10610	COG0840	transmembrane signaling receptor activity
H9L24_RS10615	COG0613	PHP domain protein
H9L24_RS10620	COG0009	L-threonylcarbamoyladenylate synthase
H9L24_RS10625	COG0840	transmembrane signaling receptor activity
H9L24_RS10630	COG1994	Peptidase M50
H9L24_RS10635	COG0180	Tryptophanyl-tRNA synthetase
H9L24_RS10640	COG1280	lysine exporter protein (LysE YggA)
H9L24_RS10650	COG0745	RESPONSE REGULATOR receiver
H9L24_RS10710	COG0582	viral genome integration into host DNA
H9L24_RS10725	COG0210	DNA helicase
H9L24_RS10785	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
H9L24_RS10790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L24_RS10795	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
H9L24_RS10795	COG0517	IMP dehydrogenase activity
H9L24_RS10795	COG0617	tRNA 3'-terminal CCA addition
H9L24_RS10800	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
H9L24_RS10805	COG1047	Peptidyl-prolyl cis-trans
H9L24_RS10810	COG2003	Belongs to the UPF0758 family
H9L24_RS10820	COG1193	negative regulation of DNA recombination
H9L24_RS10825	COG0737	Belongs to the 5'-nucleotidase family
H9L24_RS10855	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H9L24_RS10875	COG0437	4 iron, 4 sulfur cluster binding
H9L24_RS10920	COG0489	protein tyrosine kinase activity
H9L24_RS10950	COG2755	lipolytic protein G-D-S-L family
H9L24_RS10970	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H9L24_RS10975	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
H9L24_RS10990	COG0156	8-amino-7-oxononanoate synthase activity
H9L24_RS10995	COG0602	queuosine metabolic process
H9L24_RS11000	COG0720	synthase
H9L24_RS11020	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H9L24_RS11030	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
H9L24_RS11035	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
H9L24_RS11040	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
H9L24_RS11045	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
H9L24_RS11055	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H9L24_RS11060	COG0588	phosphoglycerate mutase activity
H9L24_RS11065	COG0793	Belongs to the peptidase S41A family
H9L24_RS11070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H9L24_RS11080	COG2197	response regulator
H9L24_RS11090	COG5487	UPF0391 membrane protein
H9L24_RS11110	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
H9L24_RS11115	COG0742	ribosomal rna small subunit methyltransferase
H9L24_RS11120	COG0612	Peptidase, M16
H9L24_RS11125	COG0612	Peptidase, M16
H9L24_RS11140	COG1012	belongs to the aldehyde dehydrogenase family
H9L24_RS11150	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L24_RS11185	COG1730	sister chromatid segregation
H9L24_RS11190	COG1858	cytochrome C peroxidase
H9L24_RS11205	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9L24_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS11250	COG1902	pentaerythritol trinitrate reductase activity
H9L24_RS11250	COG0446	pyridine nucleotide-disulphide oxidoreductase
H9L24_RS11280	COG1999	signal sequence binding
H9L24_RS11290	COG1612	heme a metabolic process
H9L24_RS11320	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
H9L24_RS11340	COG2226	methyltransferase
H9L24_RS11370	COG0489	protein tyrosine kinase activity
H9L24_RS11375	COG1280	lysine exporter protein (LysE YggA)
H9L24_RS11390	COG0583	DNA-binding transcription factor activity
H9L24_RS11410	COG0183	Belongs to the thiolase family
H9L24_RS11415	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H9L24_RS11425	COG1414	Transcriptional regulator
H9L24_RS11445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H9L24_RS11490	COG4773	Receptor
H9L24_RS11500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L24_RS11515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L24_RS11520	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS11530	COG0583	DNA-binding transcription factor activity
H9L24_RS11535	COG1393	Belongs to the ArsC family
H9L24_RS11550	COG1178	ABC-type Fe3 transport system permease component
H9L24_RS11575	COG0540	Belongs to the ATCase OTCase family
H9L24_RS11580	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
H9L24_RS11585	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H9L24_RS11590	COG1678	Uncharacterized ACR, COG1678
H9L24_RS11595	COG0415	Belongs to the DNA photolyase family
H9L24_RS11610	COG0840	transmembrane signaling receptor activity
H9L24_RS11630	COG1773	rubredoxin
H9L24_RS11650	COG4654	Cytochrome c, class I
H9L24_RS11655	COG0138	bifunctional purine biosynthesis protein purh
H9L24_RS11660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H9L24_RS11665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H9L24_RS11680	COG1238	metal cluster binding
H9L24_RS11685	COG3551	Protein conserved in bacteria
H9L24_RS11725	COG0012	GTP binding
H9L24_RS11730	COG0633	Ferredoxin
H9L24_RS11730	COG3217	Mosc domain protein beta barrel domain protein
H9L24_RS11740	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L24_RS11750	COG1024	Enoyl-CoA hydratase
H9L24_RS11765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
H9L24_RS11770	COG0583	DNA-binding transcription factor activity
H9L24_RS11790	COG0596	Alpha beta hydrolase
H9L24_RS11810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H9L24_RS11840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H9L24_RS11840	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L24_RS11845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H9L24_RS11855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H9L24_RS11865	COG2264	protein methyltransferase activity
H9L24_RS11870	COG0439	Biotin carboxylase
H9L24_RS11875	COG0511	ligase activity, forming carbon-carbon bonds
H9L24_RS11905	COG2203	Gaf domain
H9L24_RS11905	COG2200	EAL domain
H9L24_RS11905	COG2199	diguanylate cyclase activity
H9L24_RS11925	COG2815	serine threonine protein kinase
H9L24_RS11925	COG0515	serine threonine protein kinase
H9L24_RS11935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9L24_RS11960	COG2197	response regulator
H9L24_RS11965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS11970	COG2274	protein secretion by the type I secretion system
H9L24_RS11980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9L24_RS12000	COG2192	nodulation
H9L24_RS12010	COG0312	modulator of DNA gyrase
H9L24_RS12020	COG0772	Belongs to the SEDS family
H9L24_RS12030	COG3150	esterase
H9L24_RS12050	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H9L24_RS12055	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L24_RS12070	COG0575	Belongs to the CDS family
H9L24_RS12075	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
H9L24_RS12085	COG0840	transmembrane signaling receptor activity
H9L24_RS12100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
H9L24_RS12105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H9L24_RS12115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H9L24_RS12120	COG1181	Belongs to the D-alanine--D-alanine ligase family
H9L24_RS12125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H9L24_RS12130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
H9L24_RS12140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
H9L24_RS12145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H9L24_RS12150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H9L24_RS12155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9L24_RS12170	COG0275	rRNA processing
H9L24_RS12175	COG2001	Belongs to the MraZ family
H9L24_RS12180	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
H9L24_RS12185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
H9L24_RS12200	COG0523	cobalamin synthesis protein
H9L24_RS12215	COG3706	GGDEF domain
H9L24_RS12220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H9L24_RS12240	COG2072	flavoprotein involved in K transport
H9L24_RS12255	COG0583	DNA-binding transcription factor activity
H9L24_RS12260	COG0656	L-ascorbic acid biosynthetic process
H9L24_RS12280	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L24_RS12290	COG4269	membrane
H9L24_RS12330	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
H9L24_RS12340	COG0840	transmembrane signaling receptor activity
H9L24_RS12345	COG0501	Belongs to the peptidase M48B family
H9L24_RS12355	COG0418	dihydroorotase activity
H9L24_RS12360	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS12375	COG1126	abc transporter atp-binding protein
H9L24_RS12380	COG0765	amino acid transport
H9L24_RS12385	COG0765	amino acid transport
H9L24_RS12405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L24_RS12415	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS12425	COG5265	(ABC) transporter
H9L24_RS12445	COG1024	Enoyl-CoA hydratase
H9L24_RS12460	COG0183	Belongs to the thiolase family
H9L24_RS12470	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L24_RS12470	COG1024	Enoyl-CoA hydratase
H9L24_RS12480	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS12505	COG1309	transcriptional regulator
H9L24_RS12535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L24_RS12540	COG1802	Transcriptional regulator
H9L24_RS12565	COG1280	lysine exporter protein (LysE YggA)
H9L24_RS12570	COG1522	sequence-specific DNA binding
H9L24_RS12580	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H9L24_RS12590	COG0154	amidase activity
H9L24_RS12600	COG0204	Acyl-transferase
H9L24_RS12600	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS12620	COG1309	transcriptional regulator
H9L24_RS12640	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L24_RS12655	COG2847	Copper chaperone PCu(A)C
H9L24_RS12680	COG0203	ribosomal protein L17
H9L24_RS12685	COG0202	RNA polymerase activity
H9L24_RS12690	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
H9L24_RS12695	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
H9L24_RS12700	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H9L24_RS12705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
H9L24_RS12710	COG0201	protein transport
H9L24_RS12715	COG0200	Binds to the 23S rRNA
H9L24_RS12720	COG1841	ribosomal large subunit assembly
H9L24_RS12725	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
H9L24_RS12730	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
H9L24_RS12735	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
H9L24_RS12745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
H9L24_RS12750	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
H9L24_RS12755	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
H9L24_RS12760	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
H9L24_RS12765	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
H9L24_RS12780	COG0395	ABC-type sugar transport system, permease component
H9L24_RS12790	COG3842	ATPase activity
H9L24_RS12795	COG3842	ATPase activity
H9L24_RS12805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H9L24_RS12815	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H9L24_RS12825	COG0783	Belongs to the Dps family
H9L24_RS12850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H9L24_RS12895	COG2819	hydrolase of the alpha beta superfamily
H9L24_RS12900	COG5001	Diguanylate cyclase
H9L24_RS12900	COG4251	negative regulation of phosphorylation
H9L24_RS12900	COG3706	GGDEF domain
H9L24_RS12900	COG2203	Gaf domain
H9L24_RS12905	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
H9L24_RS12930	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
H9L24_RS12935	COG0134	indole-3-glycerol-phosphate synthase activity
H9L24_RS12945	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9L24_RS12950	COG1280	lysine exporter protein (LysE YggA)
H9L24_RS12960	COG0512	Glutamine amidotransferase of anthranilate synthase
H9L24_RS12980	COG0840	transmembrane signaling receptor activity
H9L24_RS12985	COG0546	phosphoglycolate phosphatase activity
H9L24_RS13035	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H9L24_RS13040	COG2967	ApaG domain
H9L24_RS13055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
H9L24_RS13075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS13080	COG0842	Transport permease protein
H9L24_RS13080	COG1129	ABC transporter
H9L24_RS13085	COG0842	Transport permease protein
H9L24_RS13095	COG1595	DNA-templated transcription, initiation
H9L24_RS13105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H9L24_RS13110	COG1546	Belongs to the CinA family
H9L24_RS13120	COG3012	SEC-C Motif Domain Protein
H9L24_RS13120	COG3318	Belongs to the UPF0149 family
H9L24_RS13150	COG0456	acetyltransferase
H9L24_RS13160	COG0765	amino acid transport
H9L24_RS13165	COG0765	amino acid transport
H9L24_RS13170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS13195	COG1137	ATPase activity
H9L24_RS13205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H9L24_RS13250	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS13255	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS13260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS13270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L24_RS13280	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H9L24_RS13290	COG1942	4-Oxalocrotonate Tautomerase
H9L24_RS13295	COG2814	Major facilitator Superfamily
H9L24_RS13300	COG0121	glutamine amidotransferase
H9L24_RS13310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS13320	COG1294	oxidase, subunit
H9L24_RS13325	COG1271	oxidase subunit
H9L24_RS13330	COG0348	domain, Protein
H9L24_RS13360	COG0326	Molecular chaperone. Has ATPase activity
H9L24_RS13385	COG1187	pseudouridine synthase activity
H9L24_RS13390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L24_RS13400	COG1022	Amp-dependent synthetase and ligase
H9L24_RS13440	COG0583	DNA-binding transcription factor activity
H9L24_RS13445	COG1741	Belongs to the pirin family
H9L24_RS13450	COG1335	isochorismatase
H9L24_RS13480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L24_RS13495	COG1024	Enoyl-CoA hydratase
H9L24_RS13500	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS13510	COG0251	oxidation-reduction process
H9L24_RS13530	COG2818	Glycosylase
H9L24_RS13560	COG1473	amidohydrolase
H9L24_RS13575	COG0243	molybdopterin cofactor binding
H9L24_RS13585	COG1979	alcohol dehydrogenase
H9L24_RS13630	COG3945	hemerythrin HHE cation binding domain
H9L24_RS13650	COG0288	reversible hydration of carbon dioxide
H9L24_RS13655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H9L24_RS13660	COG2181	nitrate reductase activity
H9L24_RS13665	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
H9L24_RS13670	COG1140	nitrate reductase beta subunit
H9L24_RS13675	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
H9L24_RS13690	COG2197	response regulator
H9L24_RS13705	COG5001	Diguanylate cyclase
H9L24_RS13720	COG0277	FAD linked oxidase domain protein
H9L24_RS13725	COG2733	membrane
H9L24_RS13755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H9L24_RS13765	COG2084	Dehydrogenase
H9L24_RS13770	COG2823	Periplasmic or secreted lipoprotein
H9L24_RS13775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
H9L24_RS13780	COG0792	nuclease activity
H9L24_RS13785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
H9L24_RS13790	COG0443	Heat shock 70 kDa protein
H9L24_RS13840	COG2204	response regulator
H9L24_RS13845	COG5000	phosphorelay sensor kinase activity
H9L24_RS13865	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
H9L24_RS13870	COG0085	RNA polymerase activity
H9L24_RS13875	COG0222	ribosome binding
H9L24_RS13880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
H9L24_RS13885	COG0081	regulation of translation
H9L24_RS13890	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
H9L24_RS13900	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H9L24_RS13910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
H9L24_RS13945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L24_RS13990	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H9L24_RS13995	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
H9L24_RS14000	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
H9L24_RS14005	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
H9L24_RS14010	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
H9L24_RS14015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
H9L24_RS14025	COG0356	it plays a direct role in the translocation of protons across the membrane
H9L24_RS14035	COG2921	Belongs to the UPF0250 family
H9L24_RS14040	COG0321	lipoyl(octanoyl) transferase activity
H9L24_RS14045	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H9L24_RS14060	COG1127	ABC transporter
H9L24_RS14065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L24_RS14080	COG0004	ammonium transporteR
H9L24_RS14095	COG0768	penicillin binding
H9L24_RS14110	COG1077	Cell shape determining protein MreB Mrl
H9L24_RS14115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9L24_RS14120	COG0154	amidase activity
H9L24_RS14125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H9L24_RS14140	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H9L24_RS14145	COG0708	Exodeoxyribonuclease III
H9L24_RS14150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L24_RS14155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H9L24_RS14275	COG0501	Belongs to the peptidase M48B family
H9L24_RS14290	COG2211	Major facilitator Superfamily
H9L24_RS14370	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
H9L24_RS14405	COG0747	negative chemotaxis
H9L24_RS14425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H9L24_RS14445	COG0386	Belongs to the glutathione peroxidase family
H9L24_RS14530	COG0606	chelatase, subunit chli
H9L24_RS14580	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H9L24_RS14600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
H9L24_RS14605	COG3909	cytochrome
H9L24_RS14620	COG0678	peroxiredoxin activity
H9L24_RS14625	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
H9L24_RS14630	COG0255	Belongs to the universal ribosomal protein uL29 family
H9L24_RS14635	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
H9L24_RS14640	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
H9L24_RS14645	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
H9L24_RS14650	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
H9L24_RS14655	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H9L24_RS14660	COG0089	rRNA binding
H9L24_RS14665	COG0088	Forms part of the polypeptide exit tunnel
H9L24_RS14670	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
H9L24_RS14675	COG0051	transcription antitermination factor activity, RNA binding
H9L24_RS14690	COG0049	tRNA binding
H9L24_RS14695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
H9L24_RS14700	COG1686	Belongs to the peptidase S11 family
H9L24_RS14705	COG2945	thiolester hydrolase activity
H9L24_RS14720	COG1981	membrane
H9L24_RS14735	COG0840	transmembrane signaling receptor activity
H9L24_RS14740	COG0625	glutathione transferase activity
H9L24_RS14750	COG0412	Dienelactone hydrolase
H9L24_RS14755	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS14760	COG2095	MarC family integral membrane protein
H9L24_RS14765	COG0745	RESPONSE REGULATOR receiver
H9L24_RS14770	COG2205	protein histidine kinase activity
H9L24_RS14785	COG4452	Inner membrane protein CreD
H9L24_RS14820	COG1410	methionine synthase
H9L24_RS14820	COG0646	methionine synthase
H9L24_RS14830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H9L24_RS14910	COG1116	anion transmembrane transporter activity
H9L24_RS14920	COG2326	polyphosphate kinase activity
H9L24_RS14925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H9L24_RS14950	COG2301	Belongs to the HpcH HpaI aldolase family
H9L24_RS14970	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS14975	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H9L24_RS14985	COG0583	DNA-binding transcription factor activity
H9L24_RS15000	COG0583	DNA-binding transcription factor activity
H9L24_RS15015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS15020	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS15045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L24_RS15055	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
H9L24_RS15065	COG0583	DNA-binding transcription factor activity
H9L24_RS15125	COG2267	carboxylic ester hydrolase activity
H9L24_RS15130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H9L24_RS15140	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
H9L24_RS15150	COG0850	regulation of cytokinetic process
H9L24_RS15160	COG1183	phosphatidylcholine synthase activity
H9L24_RS15170	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS15190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H9L24_RS15200	COG2199	diguanylate cyclase activity
H9L24_RS15200	COG2203	Gaf domain
H9L24_RS15225	COG2233	PERMEase
H9L24_RS15245	COG2050	protein possibly involved in aromatic compounds catabolism
H9L24_RS15250	COG2096	Adenosyltransferase
H9L24_RS15315	COG1475	DNA binding
H9L24_RS15335	COG1192	Involved in chromosome partitioning
H9L24_RS15345	COG0357	Ribosomal RNA small subunit methyltransferase G
H9L24_RS15370	COG0625	glutathione transferase activity
H9L24_RS15385	COG0745	RESPONSE REGULATOR receiver
H9L24_RS15410	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H9L24_RS15415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H9L24_RS15425	COG2217	Heavy metal translocating P-type atpase
H9L24_RS15435	COG0789	Transcriptional regulator
H9L24_RS15440	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L24_RS15480	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H9L24_RS15515	COG1022	Amp-dependent synthetase and ligase
H9L24_RS15525	COG0183	Belongs to the thiolase family
H9L24_RS15560	COG2715	membrane protein required for spore maturation
H9L24_RS15565	COG2974	May be involved in recombination
H9L24_RS15580	COG0789	Transcriptional regulator
H9L24_RS15600	COG1024	Enoyl-CoA hydratase
H9L24_RS15615	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS15620	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS15635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H9L24_RS15655	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS15660	COG4948	Mandelate Racemase Muconate Lactonizing
H9L24_RS15670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS15675	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L24_RS15680	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L24_RS15690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS15705	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS15715	COG0791	NLP P60 protein
H9L24_RS15720	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9L24_RS15740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H9L24_RS15745	COG2258	MOSC domain
H9L24_RS15765	COG2824	Alkylphosphonate utilization operon protein PhnA
H9L24_RS15795	COG1254	Belongs to the acylphosphatase family
H9L24_RS15825	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H9L24_RS15830	COG0230	Belongs to the bacterial ribosomal protein bL34 family
H9L24_RS15840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
H9L24_RS15845	COG0706	membrane insertase activity
H9L24_RS15850	COG0300	oxidoreductase activity
H9L24_RS15880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
H9L24_RS15890	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
H9L24_RS15890	COG2066	Belongs to the glutaminase family
H9L24_RS15895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
H9L24_RS15905	COG0724	RNA recognition motif
H9L24_RS15910	COG0724	RNA recognition motif
H9L24_RS15915	COG2119	membrane
H9L24_RS15920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L24_RS15925	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H9L24_RS15925	COG2813	Specifically methylates the guanine in position
H9L24_RS15935	COG2249	NAD(P)H dehydrogenase (quinone) activity
H9L24_RS15945	COG3622	Belongs to the hyi family
H9L24_RS15955	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS15960	COG0583	DNA-binding transcription factor activity
H9L24_RS15965	COG0840	transmembrane signaling receptor activity
H9L24_RS15970	COG0840	transmembrane signaling receptor activity
H9L24_RS15990	COG2814	Major facilitator Superfamily
H9L24_RS16000	COG2755	lipolytic protein G-D-S-L family
H9L24_RS16000	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H9L24_RS16030	COG0601	transmembrane transport
H9L24_RS16035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L24_RS16045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L24_RS16065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H9L24_RS16085	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H9L24_RS16100	COG0281	malic enzyme
H9L24_RS16100	COG0280	phosphate acetyltransferase
H9L24_RS16125	COG4177	L-phenylalanine transmembrane transporter activity
H9L24_RS16140	COG1802	Transcriptional regulator
H9L24_RS16175	COG4566	intracellular signal transduction
H9L24_RS16180	COG3258	Cytochrome c
H9L24_RS16225	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
H9L24_RS16245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H9L24_RS16320	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS16335	COG0482	sulfurtransferase activity
H9L24_RS16340	COG0583	DNA-binding transcription factor activity
H9L24_RS16345	COG1620	l-lactate permease
H9L24_RS16350	COG0629	single-stranded DNA binding
H9L24_RS16410	COG0765	amino acid transport
H9L24_RS16415	COG0765	amino acid transport
H9L24_RS16420	COG1126	abc transporter atp-binding protein
H9L24_RS16450	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS16455	COG0583	DNA-binding transcription factor activity
H9L24_RS16460	COG0284	orotidine-5'-phosphate decarboxylase activity
H9L24_RS16480	COG0126	phosphoglycerate kinase activity
H9L24_RS16495	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
H9L24_RS16505	COG0242	peptide deformylase activity
H9L24_RS16515	COG0758	DNA mediated transformation
H9L24_RS16525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L24_RS16530	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H9L24_RS16535	COG1862	Preprotein translocase
H9L24_RS16545	COG1522	sequence-specific DNA binding
H9L24_RS16550	COG2814	Major facilitator Superfamily
H9L24_RS16565	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
H9L24_RS16575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H9L24_RS16575	COG2885	chlorophyll binding
H9L24_RS16580	COG4566	intracellular signal transduction
H9L24_RS16615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS16630	COG0625	glutathione transferase activity
H9L24_RS16655	COG0861	Integral membrane protein TerC family
H9L24_RS16665	COG1950	PFAM Membrane protein of
H9L24_RS16670	COG4783	chaperone-mediated protein folding
H9L24_RS16675	COG0315	cyclic pyranopterin monophosphate synthase activity
H9L24_RS16685	COG3307	-O-antigen
H9L24_RS16710	COG0861	Integral membrane protein TerC family
H9L24_RS16715	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
H9L24_RS16720	COG0045	succinate-CoA ligase (ADP-forming) activity
H9L24_RS16725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
H9L24_RS16730	COG2137	regulation of response to DNA damage stimulus
H9L24_RS16735	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
H9L24_RS16750	COG0642	Histidine kinase
H9L24_RS16770	COG2814	Major facilitator Superfamily
H9L24_RS16815	COG1881	PFAM PEBP family protein
H9L24_RS16830	COG2365	Tyrosine phosphatase family
H9L24_RS16835	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS16840	COG0625	glutathione transferase activity
H9L24_RS16860	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H9L24_RS16875	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H9L24_RS16900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H9L24_RS16945	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
H9L24_RS16955	COG0006	proline dipeptidase activity
H9L24_RS16960	COG0469	pyruvate kinase activity
H9L24_RS17010	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS17015	COG0601	transmembrane transport
H9L24_RS17020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L24_RS17030	COG4608	Belongs to the ABC transporter superfamily
H9L24_RS17035	COG0747	negative chemotaxis
H9L24_RS17045	COG0598	Magnesium transport protein CorA
H9L24_RS17065	COG2027	D-alanyl-D-alanine carboxypeptidase
H9L24_RS17080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9L24_RS17085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H9L24_RS17115	COG0009	L-threonylcarbamoyladenylate synthase
H9L24_RS17120	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H9L24_RS17125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H9L24_RS17130	COG3118	belongs to the thioredoxin family
H9L24_RS17135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
H9L24_RS17140	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H9L24_RS17150	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
H9L24_RS17155	COG0735	belongs to the Fur family
H9L24_RS17160	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H9L24_RS17165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H9L24_RS17180	COG0668	transmembrane transport
H9L24_RS17185	COG0495	leucyl-tRNA aminoacylation
H9L24_RS17230	COG3158	transport of potassium into the cell
H9L24_RS17235	COG3135	benzoate transporter
H9L24_RS17275	COG0789	Transcriptional regulator
H9L24_RS17285	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS17290	COG0288	reversible hydration of carbon dioxide
H9L24_RS17295	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
H9L24_RS17300	COG0183	Belongs to the thiolase family
H9L24_RS17315	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS17365	COG3012	SEC-C Motif Domain Protein
H9L24_RS17380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS17385	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS17390	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
H9L24_RS17425	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS17430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H9L24_RS17440	COG2318	DinB family
H9L24_RS17445	COG1024	Enoyl-CoA hydratase
H9L24_RS17460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H9L24_RS17475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H9L24_RS17580	COG2423	ornithine cyclodeaminase activity
H9L24_RS17600	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H9L24_RS17610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H9L24_RS17620	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H9L24_RS17625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H9L24_RS17635	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
H9L24_RS17640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H9L24_RS17655	COG0316	Belongs to the HesB IscA family
H9L24_RS17660	COG2814	Major facilitator Superfamily
H9L24_RS17665	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H9L24_RS17670	COG0739	heme binding
H9L24_RS17675	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H9L24_RS17685	COG0583	DNA-binding transcription factor activity
H9L24_RS17700	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
H9L24_RS17705	COG2205	protein histidine kinase activity
H9L24_RS17710	COG3706	GGDEF domain
H9L24_RS17735	COG2197	response regulator
H9L24_RS17740	COG4191	Histidine kinase
H9L24_RS17745	COG1301	dicarboxylic acid transport
H9L24_RS17770	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H9L24_RS17775	COG2815	serine threonine protein kinase
H9L24_RS17775	COG0515	serine threonine protein kinase
H9L24_RS17785	COG1764	response to oxidative stress
H9L24_RS17790	COG1846	Transcriptional regulator
H9L24_RS17795	COG1250	3-hydroxyacyl-CoA dehydrogenase
H9L24_RS17815	COG1131	(ABC) transporter
H9L24_RS17820	COG3243	poly(R)-hydroxyalkanoic acid synthase
H9L24_RS17830	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
H9L24_RS17850	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H9L24_RS17865	COG0513	Belongs to the DEAD box helicase family
H9L24_RS17875	COG0666	response to abiotic stimulus
H9L24_RS17885	COG4566	intracellular signal transduction
H9L24_RS17890	COG4191	Histidine kinase
H9L24_RS17895	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
H9L24_RS17900	COG1490	D-aminoacyl-tRNA deacylase activity
H9L24_RS17905	COG0589	response to stress
H9L24_RS17910	COG0730	response to heat
H9L24_RS17915	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
H9L24_RS17920	COG1702	phosphate starvation-inducible protein PhoH
H9L24_RS17935	COG2255	four-way junction helicase activity
H9L24_RS17970	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS17990	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H9L24_RS17995	COG3387	PFAM Glycoside hydrolase 15-related
H9L24_RS18030	COG1595	DNA-templated transcription, initiation
H9L24_RS18040	COG0617	tRNA 3'-terminal CCA addition
H9L24_RS18050	COG0842	Transport permease protein
H9L24_RS18055	COG1131	(ABC) transporter
H9L24_RS18065	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H9L24_RS18080	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H9L24_RS18085	COG0741	lytic transglycosylase activity
H9L24_RS18100	COG0318	PFAM AMP-dependent synthetase and ligase
H9L24_RS18125	COG3186	Phenylalanine-4-hydroxylase
H9L24_RS18140	COG1522	sequence-specific DNA binding
H9L24_RS18160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
H9L24_RS18170	COG0583	DNA-binding transcription factor activity
H9L24_RS18180	COG0752	glycyl-tRNA synthetase alpha subunit
H9L24_RS18190	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
H9L24_RS18195	COG0204	Acyl-transferase
H9L24_RS18210	COG1652	LysM domain
H9L24_RS18215	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
H9L24_RS18235	COG4221	oxidoreductase activity
H9L24_RS18265	COG0463	Glycosyl transferase, family 2
H9L24_RS18265	COG1216	Glycosyl transferase, family 2
H9L24_RS18270	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H9L24_RS18320	COG1450	Type ii and iii secretion system protein
H9L24_RS18395	COG0741	lytic transglycosylase activity
H9L24_RS18395	COG1196	nuclear chromosome segregation
H9L24_RS18395	COG0739	heme binding
H9L24_RS18405	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
H9L24_RS18410	COG0745	RESPONSE REGULATOR receiver
H9L24_RS18415	COG0642	Histidine kinase
H9L24_RS18425	COG0343	queuine tRNA-ribosyltransferase activity
H9L24_RS18450	COG0210	DNA helicase
H9L24_RS18460	COG0679	Auxin Efflux Carrier
H9L24_RS18480	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
H9L24_RS18485	COG3237	CsbD-like
H9L24_RS18495	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS18500	COG3119	arylsulfatase activity
H9L24_RS18515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L24_RS18525	COG1414	Transcriptional regulator
H9L24_RS18535	COG1832	CoA-binding protein
H9L24_RS18565	COG0583	DNA-binding transcription factor activity
H9L24_RS18615	COG3181	Tripartite tricarboxylate transporter family receptor
H9L24_RS18655	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L24_RS18670	COG0384	phenazine biosynthesis protein PhzF
H9L24_RS18690	COG0697	spore germination
H9L24_RS18700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS18710	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
H9L24_RS18730	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
H9L24_RS18740	COG4787	bacterial-type flagellum-dependent cell motility
H9L24_RS18750	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
H9L24_RS18755	COG1558	bacterial-type flagellum-dependent cell motility
H9L24_RS18760	COG1815	bacterial-type flagellum-dependent cell motility
H9L24_RS18805	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
H9L24_RS18810	COG0745	RESPONSE REGULATOR receiver
H9L24_RS18840	COG1516	flagellar protein fliS
H9L24_RS18850	COG1677	Flagellar hook-basal body complex protein FliE
H9L24_RS18895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
H9L24_RS18905	COG1987	bacterial-type flagellum assembly
H9L24_RS18915	COG2197	response regulator
H9L24_RS18930	COG2201	protein-glutamate methylesterase activity
H9L24_RS18940	COG0835	chemotaxis
H9L24_RS18945	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
H9L24_RS18950	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
H9L24_RS18955	COG2201	protein-glutamate methylesterase activity
H9L24_RS18960	COG0488	(ABC) transporter
H9L24_RS18995	COG2814	Major facilitator Superfamily
H9L24_RS19000	COG1566	PFAM secretion protein HlyD family protein
H9L24_RS19010	COG1846	Transcriptional regulator
H9L24_RS19015	COG4941	Belongs to the sigma-70 factor family
H9L24_RS19035	COG3795	YCII-related domain
H9L24_RS19045	COG0183	Belongs to the thiolase family
H9L24_RS19060	COG3045	CreA protein
H9L24_RS19070	COG0189	ligase activity
H9L24_RS19070	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H9L24_RS19075	COG1132	(ABC) transporter
H9L24_RS19100	COG0004	ammonium transporteR
H9L24_RS19110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H9L24_RS19185	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H9L24_RS19195	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
H9L24_RS19220	COG0747	negative chemotaxis
H9L24_RS19225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L24_RS19230	COG0444	Belongs to the ABC transporter superfamily
H9L24_RS19235	COG4608	Belongs to the ABC transporter superfamily
H9L24_RS19240	COG0737	Belongs to the 5'-nucleotidase family
H9L24_RS19245	COG1881	PFAM PEBP family protein
H9L24_RS19270	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
H9L24_RS19280	COG0166	Belongs to the GPI family
H9L24_RS19295	COG2169	Transcriptional regulator
H9L24_RS19295	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H9L24_RS19300	COG0459	protein refolding
H9L24_RS19305	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
H9L24_RS19330	COG1215	transferase activity, transferring glycosyl groups
H9L24_RS19340	COG0463	Glycosyl transferase, family 2
H9L24_RS19355	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
H9L24_RS19375	COG0175	sulfate reduction
H9L24_RS19395	COG1056	cytidyltransferase-related domain
H9L24_RS19395	COG1051	belongs to the nudix hydrolase family
H9L24_RS19410	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
H9L24_RS19430	COG0218	Necessary for normal cell division and for the maintenance of normal septation
H9L24_RS19440	COG1333	cytochrome c biogenesis protein
H9L24_RS19450	COG2205	protein histidine kinase activity
H9L24_RS19450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS19470	COG0745	RESPONSE REGULATOR receiver
H9L24_RS19475	COG0745	RESPONSE REGULATOR receiver
H9L24_RS19485	COG3706	GGDEF domain
H9L24_RS19490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
H9L24_RS19495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
H9L24_RS19500	COG2186	Transcriptional regulator
H9L24_RS19505	COG2084	Dehydrogenase
H9L24_RS19510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H9L24_RS19515	COG3395	kinase activity
H9L24_RS19525	COG3622	Belongs to the hyi family
H9L24_RS19535	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS19545	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L24_RS19545	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
H9L24_RS19555	COG1850	ribulose-bisphosphate carboxylase activity
H9L24_RS19565	COG2186	Transcriptional regulator
H9L24_RS19575	COG2186	Transcriptional regulator
H9L24_RS19585	COG2084	Dehydrogenase
H9L24_RS19610	COG1965	Belongs to the frataxin family
H9L24_RS19650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
H9L24_RS19660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H9L24_RS19680	COG0067	glutamate synthase
H9L24_RS19680	COG0069	glutamate synthase activity
H9L24_RS19680	COG0070	glutamate synthase
H9L24_RS19695	COG0765	amino acid transport
H9L24_RS19700	COG1126	abc transporter atp-binding protein
H9L24_RS19705	COG1127	ABC transporter
H9L24_RS19710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H9L24_RS19715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H9L24_RS19720	COG2853	Lipoprotein
H9L24_RS19735	COG1131	(ABC) transporter
H9L24_RS19740	COG0842	Transport permease protein
H9L24_RS19745	COG5007	Belongs to the BolA IbaG family
H9L24_RS19750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H9L24_RS19755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H9L24_RS19770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H9L24_RS19785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H9L24_RS19790	COG0131	Imidazoleglycerol-phosphate dehydratase
H9L24_RS19800	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
H9L24_RS19805	COG0107	imidazoleglycerol-phosphate synthase activity
H9L24_RS19815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H9L24_RS19820	COG0140	phosphoribosyl-ATP diphosphatase activity
H9L24_RS19835	COG0537	adenosine 5'-monophosphoramidase activity
H9L24_RS19840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L24_RS19845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H9L24_RS19850	COG0805	protein transport
H9L24_RS19855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H9L24_RS19865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H9L24_RS19870	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H9L24_RS19875	COG1970	mechanosensitive ion channel activity
H9L24_RS19880	COG0723	plastoquinol--plastocyanin reductase activity
H9L24_RS19885	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
H9L24_RS19890	COG2857	Cytochrome c1
H9L24_RS19895	COG0625	glutathione transferase activity
H9L24_RS19900	COG2969	positive regulation of protein catabolic process
H9L24_RS19915	COG0739	heme binding
H9L24_RS19920	COG0653	protein targeting
H9L24_RS19935	COG0494	nUDIX hydrolase
H9L24_RS19940	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H9L24_RS19945	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
H9L24_RS19950	COG0237	dephospho-CoA kinase activity
H9L24_RS19955	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H9L24_RS19975	COG0142	geranyltranstransferase activity
H9L24_RS19980	COG0261	This protein binds to 23S rRNA in the presence of protein L20
H9L24_RS19985	COG0211	Belongs to the bacterial ribosomal protein bL27 family
H9L24_RS19990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
H9L24_RS19995	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
H9L24_RS20000	COG0494	nUDIX hydrolase
H9L24_RS20005	COG0442	prolyl-tRNA aminoacylation
H9L24_RS20015	COG1253	flavin adenine dinucleotide binding
H9L24_RS20045	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
H9L24_RS20050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H9L24_RS20055	COG2890	protein-(glutamine-N5) methyltransferase activity
H9L24_RS20060	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
H9L24_RS20065	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
H9L24_RS20090	COG0584	glycerophosphoryl diester phosphodiesterase
H9L24_RS20095	COG3842	ATPase activity
H9L24_RS20105	COG1175	transmembrane transport
H9L24_RS20140	COG2226	methyltransferase
H9L24_RS20155	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H9L24_RS20195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H9L24_RS20200	COG0302	gtp cyclohydrolase
H9L24_RS20235	COG0588	phosphoglycerate mutase activity
H9L24_RS20245	COG0583	DNA-binding transcription factor activity
H9L24_RS20250	COG0154	amidase activity
H9L24_RS20255	COG0747	negative chemotaxis
H9L24_RS20260	COG4608	Belongs to the ABC transporter superfamily
H9L24_RS20270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H9L24_RS20280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H9L24_RS20290	COG4302	ethanolamine ammonia-lyase activity
H9L24_RS20295	COG4303	Ethanolamine ammonia lyase large subunit
H9L24_RS20300	COG0531	amino acid
H9L24_RS20310	COG0193	aminoacyl-tRNA hydrolase activity
H9L24_RS20315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
H9L24_RS20320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H9L24_RS20330	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
H9L24_RS20335	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H9L24_RS20345	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
H9L24_RS20355	COG1194	a g-specific adenine glycosylase
H9L24_RS20360	COG1660	Displays ATPase and GTPase activities
H9L24_RS20365	COG0497	DNA recombination
H9L24_RS20375	COG1420	regulation of RNA biosynthetic process
H9L24_RS20395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H9L24_RS20400	COG1758	RNA polymerase activity
H9L24_RS20405	COG0194	GDP metabolic process
H9L24_RS20410	COG1561	YicC-like family, N-terminal region
H9L24_RS20420	COG0631	protein serine/threonine phosphatase activity
H9L24_RS20430	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H9L24_RS20495	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
H9L24_RS20500	COG0830	nickel cation binding
H9L24_RS20505	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
H9L24_RS20520	COG0832	Belongs to the urease beta subunit family
H9L24_RS20530	COG0831	urea catabolic process
H9L24_RS20535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H9L24_RS20535	COG2205	protein histidine kinase activity
H9L24_RS20565	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H9L24_RS20570	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
H9L24_RS20575	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
H9L24_RS20580	COG4770	biotin carboxylase activity
H9L24_RS20585	COG1301	dicarboxylic acid transport
H9L24_RS20620	COG0829	nickel cation binding
H9L24_RS20630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L24_RS20640	COG2814	Major facilitator Superfamily
H9L24_RS20650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9L24_RS20655	COG1116	anion transmembrane transporter activity
H9L24_RS20665	COG0280	phosphate acetyltransferase
H9L24_RS20665	COG0281	malic enzyme
H9L24_RS20670	COG2233	PERMEase
H9L24_RS20685	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H9L24_RS20700	COG2186	Transcriptional regulator
H9L24_RS20705	COG0583	DNA-binding transcription factor activity
H9L24_RS20725	COG0583	DNA-binding transcription factor activity
H9L24_RS20730	COG3960	tartronate-semialdehyde synthase activity
H9L24_RS20735	COG3622	Belongs to the hyi family
H9L24_RS20740	COG2084	Dehydrogenase
H9L24_RS20745	COG0405	Gamma-glutamyltransferase
H9L24_RS20770	COG5001	Diguanylate cyclase
H9L24_RS20770	COG3300	MHYT domain
H9L24_RS20780	COG5002	protein histidine kinase activity
H9L24_RS20780	COG5001	Diguanylate cyclase
H9L24_RS20780	COG3447	MASE1 domain protein
H9L24_RS20795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H9L24_RS20810	COG3845	ABC transporter
H9L24_RS20815	COG4603	Belongs to the binding-protein-dependent transport system permease family
H9L24_RS20830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H9L24_RS20840	COG0765	amino acid transport
H9L24_RS20865	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H9L24_RS20890	COG0717	Belongs to the dCTP deaminase family
H9L24_RS20900	COG2423	ornithine cyclodeaminase activity
H9L24_RS20905	COG2321	neutral zinc metallopeptidase
H9L24_RS20910	COG0513	Belongs to the DEAD box helicase family
H9L24_RS20925	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
H9L24_RS20965	COG1253	flavin adenine dinucleotide binding
H9L24_RS20970	COG2916	Histone family protein nucleoid-structuring protein H-NS
H9L24_RS20975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H9L24_RS20980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H9L24_RS21005	COG3483	tryptophan 2,3-dioxygenase activity
H9L24_RS21015	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
H9L24_RS21020	COG1522	sequence-specific DNA binding
H9L24_RS21025	COG0727	PFAM Uncharacterised protein family (UPF0153)
H9L24_RS21045	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
H9L24_RS21050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H9L24_RS21060	COG0268	Binds directly to 16S ribosomal RNA
H9L24_RS21065	COG0728	peptidoglycan biosynthetic process
H9L24_RS21085	COG0589	response to stress
H9L24_RS21095	COG4977	sequence-specific DNA binding
H9L24_RS21120	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
H9L24_RS21125	COG0405	Gamma-glutamyltransferase
H9L24_RS21140	COG0617	tRNA 3'-terminal CCA addition
H9L24_RS21145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H9L24_RS21200	COG0583	DNA-binding transcription factor activity
H9L24_RS21205	COG2910	NAD(P)H-binding
H9L24_RS21215	COG0840	transmembrane signaling receptor activity
H9L24_RS21220	COG1309	transcriptional regulator
H9L24_RS21225	COG0493	'glutamate synthase
H9L24_RS21235	COG1953	Uracil, thiamine, allantoin
H9L24_RS21255	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H9L24_RS21260	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS21265	COG0583	DNA-binding transcription factor activity
H9L24_RS21335	COG2816	NAD+ diphosphatase activity
H9L24_RS21340	COG0425	Belongs to the sulfur carrier protein TusA family
H9L24_RS21345	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H9L24_RS21350	COG0525	valine-tRNA ligase activity
H9L24_RS21360	COG0488	(ABC) transporter
H9L24_RS21385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS21410	COG1587	Uroporphyrinogen-III synthase
H9L24_RS21415	COG0181	hydroxymethylbilane synthase activity
H9L24_RS21420	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H9L24_RS21425	COG5001	Diguanylate cyclase
H9L24_RS21475	COG1722	exodeoxyribonuclease VII activity
H9L24_RS21480	COG0142	geranyltranstransferase activity
H9L24_RS21485	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H9L24_RS21490	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H9L24_RS21495	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
H9L24_RS21525	COG1122	ATPase activity
H9L24_RS21605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H9L24_RS21630	COG4133	protoheme IX ABC transporter activity
H9L24_RS21650	COG3275	phosphorelay sensor kinase activity
H9L24_RS21715	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
H9L24_RS21735	COG0483	inositol monophosphate 1-phosphatase activity
H9L24_RS21755	COG1063	alcohol dehydrogenase
H9L24_RS21760	COG0521	Mo-molybdopterin cofactor biosynthetic process
H9L24_RS21765	COG3028	Belongs to the UPF0307 family
H9L24_RS21770	COG0312	modulator of DNA gyrase
H9L24_RS21810	COG0583	DNA-binding transcription factor activity
H9L24_RS21815	COG1942	4-Oxalocrotonate Tautomerase
H9L24_RS21825	COG0473	3-isopropylmalate dehydrogenase activity
H9L24_RS21830	COG0583	DNA-binding transcription factor activity
H9L24_RS21835	COG1610	YqeY-like protein
H9L24_RS21840	COG0828	Belongs to the bacterial ribosomal protein bS21 family
H9L24_RS21860	COG2081	HI0933 family
H9L24_RS21875	COG1607	acyl-coa hydrolase
H9L24_RS21885	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H9L24_RS21890	COG0243	molybdopterin cofactor binding
H9L24_RS21905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H9L24_RS21920	COG0517	IMP dehydrogenase activity
H9L24_RS21930	COG1116	anion transmembrane transporter activity
H9L24_RS21935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H9L24_RS21940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H9L24_RS21945	COG3707	response regulator
H9L24_RS21955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
H9L24_RS21965	COG0683	leucine binding
H9L24_RS21970	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
H9L24_RS21980	COG0583	DNA-binding transcription factor activity
H9L24_RS21985	COG1028	Short-chain dehydrogenase reductase Sdr
H9L24_RS21990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
H9L24_RS22000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
H9L24_RS22005	COG3959	Transketolase, thiamine diphosphate binding domain
H9L24_RS22010	COG3958	Transketolase
H9L24_RS22015	COG2951	lytic endotransglycosylase activity
H9L24_RS22030	COG0714	Associated with various cellular activities
H9L24_RS22035	COG0123	including yeast histone deacetylase and acetoin utilization protein
H9L24_RS22045	COG3264	Mechanosensitive ion channel
H9L24_RS22045	COG1196	nuclear chromosome segregation
H9L24_RS22060	COG1960	acyl-CoA dehydrogenase activity
H9L24_RS22070	COG3228	Belongs to the MtfA family
H9L24_RS22075	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H9L24_RS22090	COG3063	Type IV pilus biogenesis stability protein PilW
H9L24_RS22095	COG0215	cysteine-tRNA ligase activity
H9L24_RS22105	COG0825	malonyl-CoA metabolic process
H9L24_RS22115	COG0037	tRNA processing
H9L24_RS22135	COG0582	viral genome integration into host DNA