locus-tag	class	description
EAG14_RS00085	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_RS00090	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_RS00105	COG0315	cyclic pyranopterin monophosphate synthase activity
EAG14_RS00115	COG1950	PFAM Membrane protein of
EAG14_RS00125	COG0861	Integral membrane protein TerC family
EAG14_RS00130	COG0861	Integral membrane protein TerC family
EAG14_RS00155	COG0625	glutathione transferase activity
EAG14_RS00160	COG1309	transcriptional regulator
EAG14_RS00165	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_RS00170	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS00175	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS00180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
EAG14_RS00190	COG0300	oxidoreductase activity
EAG14_RS00210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EAG14_RS00255	COG0840	transmembrane signaling receptor activity
EAG14_RS00315	COG0702	epimerase
EAG14_RS00320	COG2814	Major facilitator Superfamily
EAG14_RS00325	COG1522	sequence-specific DNA binding
EAG14_RS00335	COG1862	Preprotein translocase
EAG14_RS00340	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAG14_RS00345	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EAG14_RS00355	COG0758	DNA mediated transformation
EAG14_RS00365	COG0242	peptide deformylase activity
EAG14_RS00375	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
EAG14_RS00390	COG0126	phosphoglycerate kinase activity
EAG14_RS00400	COG0284	orotidine-5'-phosphate decarboxylase activity
EAG14_RS00405	COG0583	DNA-binding transcription factor activity
EAG14_RS00430	COG1454	alcohol dehydrogenase
EAG14_RS00435	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS00440	COG3284	Transcriptional regulator
EAG14_RS00470	COG2207	Transcriptional regulator
EAG14_RS00480	COG2814	Major facilitator Superfamily
EAG14_RS00485	COG0629	single-stranded DNA binding
EAG14_RS00490	COG3552	Protein containing von Willebrand factor type A (VWA) domain
EAG14_RS00500	COG3831	ATPase activity
EAG14_RS00515	COG0714	Associated with various cellular activities
EAG14_RS00525	COG0482	sulfurtransferase activity
EAG14_RS00530	COG0840	transmembrane signaling receptor activity
EAG14_RS00540	COG1053	succinate dehydrogenase
EAG14_RS00550	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS00565	COG0583	DNA-binding transcription factor activity
EAG14_RS00585	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
EAG14_RS00600	COG3154	lipid carrier protein
EAG14_RS00605	COG0826	peptidase U32
EAG14_RS00610	COG0826	peptidase U32
EAG14_RS00615	COG2267	carboxylic ester hydrolase activity
EAG14_RS00630	COG2249	NAD(P)H dehydrogenase (quinone) activity
EAG14_RS00635	COG2813	Specifically methylates the guanine in position
EAG14_RS00635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAG14_RS00640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EAG14_RS00645	COG2119	membrane
EAG14_RS00650	COG0724	RNA recognition motif
EAG14_RS00655	COG0724	RNA recognition motif
EAG14_RS00670	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EAG14_RS00675	COG0517	IMP dehydrogenase activity
EAG14_RS00675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EAG14_RS00690	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EAG14_RS00695	COG4175	Glycine betaine
EAG14_RS00700	COG4176	ABC-type proline glycine betaine transport system permease component
EAG14_RS00705	COG2113	Glycine betaine
EAG14_RS00735	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
EAG14_RS00740	COG0784	Response regulator, receiver
EAG14_RS00740	COG2205	protein histidine kinase activity
EAG14_RS00740	COG2198	Histidine kinase
EAG14_RS00745	COG3437	response regulator, receiver
EAG14_RS00790	COG0583	DNA-binding transcription factor activity
EAG14_RS00795	COG0667	Aldo Keto reductase
EAG14_RS00855	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_RS00860	COG0840	transmembrane signaling receptor activity
EAG14_RS00890	COG0346	lactoylglutathione lyase activity
EAG14_RS00895	COG3550	peptidyl-serine autophosphorylation
EAG14_RS00920	COG0419	ATPase involved in DNA repair
EAG14_RS00925	COG0420	3'-5' exonuclease activity
EAG14_RS00945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS00950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_RS00965	COG3148	PFAM DTW domain containing protein
EAG14_RS00985	COG0840	transmembrane signaling receptor activity
EAG14_RS00995	COG0583	DNA-binding transcription factor activity
EAG14_RS01000	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS01015	COG2378	regulation of single-species biofilm formation
EAG14_RS01070	COG0625	glutathione transferase activity
EAG14_RS01110	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
EAG14_RS01125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EAG14_RS01125	COG1648	precorrin-2 dehydrogenase activity
EAG14_RS01130	COG2010	Cytochrome c
EAG14_RS01135	COG3391	amine dehydrogenase activity
EAG14_RS01155	COG0535	radical SAM domain protein
EAG14_RS01215	COG0583	DNA-binding transcription factor activity
EAG14_RS01230	COG2159	amidohydrolase
EAG14_RS01280	COG0667	Aldo Keto reductase
EAG14_RS01285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EAG14_RS01290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EAG14_RS01295	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
EAG14_RS01300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAG14_RS01310	COG0006	proline dipeptidase activity
EAG14_RS01320	COG0671	phosphoesterase, PA-phosphatase related
EAG14_RS01335	COG0642	Histidine kinase
EAG14_RS01370	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS01375	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAG14_RS01380	COG0598	Magnesium transport protein CorA
EAG14_RS01395	COG1214	PFAM Peptidase M22, glycoprotease
EAG14_RS01400	COG0840	transmembrane signaling receptor activity
EAG14_RS01435	COG0009	L-threonylcarbamoyladenylate synthase
EAG14_RS01440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EAG14_RS01450	COG3118	belongs to the thioredoxin family
EAG14_RS01455	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
EAG14_RS01465	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EAG14_RS01475	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
EAG14_RS01480	COG0735	belongs to the Fur family
EAG14_RS01485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAG14_RS01490	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
EAG14_RS01505	COG0495	leucyl-tRNA aminoacylation
EAG14_RS01515	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
EAG14_RS01545	COG0601	transmembrane transport
EAG14_RS01560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_RS01570	COG0840	transmembrane signaling receptor activity
EAG14_RS01590	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
EAG14_RS01600	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EAG14_RS01610	COG3158	transport of potassium into the cell
EAG14_RS01615	COG3135	benzoate transporter
EAG14_RS01620	COG0189	ligase activity
EAG14_RS01650	COG0121	glutamine amidotransferase
EAG14_RS01660	COG1942	4-Oxalocrotonate Tautomerase
EAG14_RS01675	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EAG14_RS01700	COG1301	dicarboxylic acid transport
EAG14_RS01715	COG0018	arginyl-trna synthetase
EAG14_RS01725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAG14_RS01735	COG1137	ATPase activity
EAG14_RS01770	COG0069	glutamate synthase activity
EAG14_RS01780	COG0659	secondary active sulfate transmembrane transporter activity
EAG14_RS01810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS01820	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EAG14_RS01840	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS01850	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
EAG14_RS01865	COG2967	ApaG domain
EAG14_RS01870	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EAG14_RS01900	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS01905	COG0583	DNA-binding transcription factor activity
EAG14_RS01910	COG0546	phosphoglycolate phosphatase activity
EAG14_RS01930	COG0512	Glutamine amidotransferase of anthranilate synthase
EAG14_RS01935	COG1280	lysine exporter protein (LysE YggA)
EAG14_RS01940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAG14_RS01950	COG0134	indole-3-glycerol-phosphate synthase activity
EAG14_RS01955	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
EAG14_RS01960	COG2885	chlorophyll binding
EAG14_RS02005	COG0783	Belongs to the Dps family
EAG14_RS02010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EAG14_RS02050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EAG14_RS02065	COG3842	ATPase activity
EAG14_RS02080	COG0395	ABC-type sugar transport system, permease component
EAG14_RS02095	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EAG14_RS02100	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EAG14_RS02105	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
EAG14_RS02110	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
EAG14_RS02115	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
EAG14_RS02120	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
EAG14_RS02125	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
EAG14_RS02130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
EAG14_RS02135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
EAG14_RS02140	COG1841	ribosomal large subunit assembly
EAG14_RS02145	COG0200	Binds to the 23S rRNA
EAG14_RS02150	COG0201	protein transport
EAG14_RS02155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EAG14_RS02160	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
EAG14_RS02165	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
EAG14_RS02170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EAG14_RS02175	COG0202	RNA polymerase activity
EAG14_RS02180	COG0203	ribosomal protein L17
EAG14_RS02190	COG0583	DNA-binding transcription factor activity
EAG14_RS02225	COG2847	Copper chaperone PCu(A)C
EAG14_RS02280	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS02280	COG0204	Acyl-transferase
EAG14_RS02295	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EAG14_RS02360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAG14_RS02380	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS02385	COG1090	epimerase
EAG14_RS02395	COG3706	GGDEF domain
EAG14_RS02400	COG0343	queuine tRNA-ribosyltransferase activity
EAG14_RS02425	COG0210	DNA helicase
EAG14_RS02460	COG0405	Gamma-glutamyltransferase
EAG14_RS02470	COG2382	esterase
EAG14_RS02485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
EAG14_RS02490	COG2814	Major facilitator Superfamily
EAG14_RS02495	COG0583	DNA-binding transcription factor activity
EAG14_RS02500	COG0861	Integral membrane protein TerC family
EAG14_RS02510	COG1832	CoA-binding protein
EAG14_RS02535	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAG14_RS02575	COG1280	lysine exporter protein (LysE YggA)
EAG14_RS02585	COG0384	phenazine biosynthesis protein PhzF
EAG14_RS02595	COG0625	glutathione transferase activity
EAG14_RS02600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS02620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS02650	COG4191	Histidine kinase
EAG14_RS02655	COG4566	intracellular signal transduction
EAG14_RS02660	COG4566	intracellular signal transduction
EAG14_RS02665	COG2910	NAD(P)H-binding
EAG14_RS02670	COG0583	DNA-binding transcription factor activity
EAG14_RS02695	COG1706	bacterial-type flagellum-dependent cell motility
EAG14_RS02710	COG4787	bacterial-type flagellum-dependent cell motility
EAG14_RS02725	COG1558	bacterial-type flagellum-dependent cell motility
EAG14_RS02730	COG1815	bacterial-type flagellum-dependent cell motility
EAG14_RS02750	COG1191	sigma factor activity
EAG14_RS02765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_RS02775	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EAG14_RS02780	COG0745	RESPONSE REGULATOR receiver
EAG14_RS02785	COG1360	Flagellar Motor Protein
EAG14_RS02845	COG1516	flagellar protein fliS
EAG14_RS02855	COG1677	Flagellar hook-basal body complex protein FliE
EAG14_RS02890	COG1580	Controls the rotational direction of flagella during chemotaxis
EAG14_RS02910	COG1338	Plays a role in the flagellum-specific transport system
EAG14_RS02915	COG1987	bacterial-type flagellum assembly
EAG14_RS02925	COG2197	response regulator
EAG14_RS02940	COG2201	protein-glutamate methylesterase activity
EAG14_RS02950	COG0835	chemotaxis
EAG14_RS02955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EAG14_RS02960	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
EAG14_RS02965	COG2201	protein-glutamate methylesterase activity
EAG14_RS02970	COG0488	(ABC) transporter
EAG14_RS03010	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS03020	COG0288	reversible hydration of carbon dioxide
EAG14_RS03025	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
EAG14_RS03030	COG0183	Belongs to the thiolase family
EAG14_RS03045	COG0300	oxidoreductase activity
EAG14_RS03050	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS03055	COG2323	membrane
EAG14_RS03065	COG3012	SEC-C Motif Domain Protein
EAG14_RS03075	COG1994	Peptidase M50
EAG14_RS03080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAG14_RS03105	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS03110	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAG14_RS03120	COG1506	peptidase
EAG14_RS03120	COG0823	Involved in the tonB-independent uptake of proteins
EAG14_RS03130	COG1024	Enoyl-CoA hydratase
EAG14_RS03145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_RS03150	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS03155	COG3246	L-lysine catabolic process to acetate
EAG14_RS03160	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS03165	COG0583	DNA-binding transcription factor activity
EAG14_RS03205	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAG14_RS03220	COG0683	leucine binding
EAG14_RS03225	COG0683	leucine binding
EAG14_RS03230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EAG14_RS03255	COG2423	ornithine cyclodeaminase activity
EAG14_RS03300	COG4154	Belongs to the RbsD FucU family
EAG14_RS03340	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EAG14_RS03355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EAG14_RS03360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EAG14_RS03370	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
EAG14_RS03375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EAG14_RS03390	COG0316	Belongs to the HesB IscA family
EAG14_RS03395	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EAG14_RS03400	COG0739	heme binding
EAG14_RS03405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EAG14_RS03415	COG0583	DNA-binding transcription factor activity
EAG14_RS03425	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAG14_RS03430	COG2205	protein histidine kinase activity
EAG14_RS03435	COG1522	sequence-specific DNA binding
EAG14_RS03460	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_RS03470	COG0601	transmembrane transport
EAG14_RS03475	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS03480	COG0444	Belongs to the ABC transporter superfamily
EAG14_RS03485	COG4608	Belongs to the ABC transporter superfamily
EAG14_RS03495	COG2151	metal-sulfur cluster biosynthetic enzyme
EAG14_RS03510	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS03525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EAG14_RS03530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_RS03555	COG3386	PFAM SMP-30 Gluconolaconase
EAG14_RS03565	COG2011	ABC-type metal ion transport system permease component
EAG14_RS03580	COG1464	Belongs to the NlpA lipoprotein family
EAG14_RS03590	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS03610	COG1965	Belongs to the frataxin family
EAG14_RS03645	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
EAG14_RS03670	COG0070	glutamate synthase
EAG14_RS03670	COG0067	glutamate synthase
EAG14_RS03670	COG0069	glutamate synthase activity
EAG14_RS03680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS03685	COG0765	amino acid transport
EAG14_RS03695	COG1127	ABC transporter
EAG14_RS03700	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAG14_RS03705	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EAG14_RS03710	COG2853	Lipoprotein
EAG14_RS03725	COG1131	(ABC) transporter
EAG14_RS03730	COG0842	Transport permease protein
EAG14_RS03735	COG5007	Belongs to the BolA IbaG family
EAG14_RS03740	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EAG14_RS03745	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EAG14_RS03760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS03770	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_RS03775	COG0800	Aldolase
EAG14_RS03780	COG3734	2-keto-3-deoxy-galactonokinase
EAG14_RS03795	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS03800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS03805	COG1129	ABC transporter
EAG14_RS03810	COG4214	carbohydrate transport
EAG14_RS03820	COG4213	ABC transporter substrate-binding protein
EAG14_RS03825	COG1879	ABC-type sugar transport system periplasmic component
EAG14_RS03830	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS03840	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS03845	COG3386	PFAM SMP-30 Gluconolaconase
EAG14_RS03850	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EAG14_RS03855	COG0745	RESPONSE REGULATOR receiver
EAG14_RS03860	COG2205	protein histidine kinase activity
EAG14_RS03865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS03880	COG2721	sulfolactate sulfo-lyase activity
EAG14_RS03885	COG1609	Transcriptional regulator
EAG14_RS03895	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_RS03905	COG0583	DNA-binding transcription factor activity
EAG14_RS03910	COG4948	Mandelate Racemase Muconate Lactonizing
EAG14_RS03965	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EAG14_RS03965	COG0617	tRNA 3'-terminal CCA addition
EAG14_RS03965	COG3620	sequence-specific DNA binding
EAG14_RS03970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS03980	COG2175	clavaminate synthase activity
EAG14_RS03990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS03995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS04010	COG3119	arylsulfatase activity
EAG14_RS04015	COG0583	DNA-binding transcription factor activity
EAG14_RS04020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS04070	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS04105	COG2814	Major facilitator Superfamily
EAG14_RS04115	COG2358	TRAP transporter, solute receptor (TAXI family
EAG14_RS04125	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS04130	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_RS04135	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS04155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS04160	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EAG14_RS04165	COG4521	taurine ABC transporter
EAG14_RS04170	COG2175	clavaminate synthase activity
EAG14_RS04180	COG1045	serine acetyltransferase
EAG14_RS04190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_RS04195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EAG14_RS04200	COG0798	PFAM Bile acid sodium symporter
EAG14_RS04225	COG5001	Diguanylate cyclase
EAG14_RS04225	COG3300	MHYT domain
EAG14_RS04240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EAG14_RS04245	COG3045	CreA protein
EAG14_RS04250	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAG14_RS04250	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAG14_RS04255	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAG14_RS04255	COG0189	ligase activity
EAG14_RS04260	COG1132	(ABC) transporter
EAG14_RS04295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS04310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
EAG14_RS04315	COG4589	Belongs to the CDS family
EAG14_RS04355	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_RS04360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_RS04370	COG0557	exoribonuclease II activity
EAG14_RS04380	COG3150	esterase
EAG14_RS04385	COG2815	serine threonine protein kinase
EAG14_RS04385	COG0515	serine threonine protein kinase
EAG14_RS04390	COG0772	Belongs to the SEDS family
EAG14_RS04395	COG3422	double-strand break repair
EAG14_RS04410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAG14_RS04420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAG14_RS04425	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS04430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_RS04440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAG14_RS04445	COG2188	Transcriptional regulator
EAG14_RS04450	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAG14_RS04460	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_RS04495	COG0642	Histidine kinase
EAG14_RS04500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAG14_RS04505	COG1943	Transposase
EAG14_RS04510	COG1522	sequence-specific DNA binding
EAG14_RS04530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_RS04535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_RS04580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_RS04590	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_RS04620	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAG14_RS04670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAG14_RS04690	COG1414	Transcriptional regulator
EAG14_RS04700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAG14_RS04705	COG0183	Belongs to the thiolase family
EAG14_RS04710	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS04715	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS04730	COG0511	ligase activity, forming carbon-carbon bonds
EAG14_RS04735	COG0439	Biotin carboxylase
EAG14_RS04740	COG2264	protein methyltransferase activity
EAG14_RS04755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_RS04770	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAG14_RS04770	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAG14_RS04775	COG3023	N-Acetylmuramoyl-L-alanine amidase
EAG14_RS04795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAG14_RS04800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EAG14_RS04825	COG0314	molybdopterin synthase activity
EAG14_RS04830	COG0542	response to heat
EAG14_RS04845	COG2205	protein histidine kinase activity
EAG14_RS04845	COG0784	Response regulator, receiver
EAG14_RS04850	COG2197	response regulator
EAG14_RS04880	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EAG14_RS04885	COG0004	ammonium transporteR
EAG14_RS04895	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAG14_RS04895	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EAG14_RS04930	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_RS04940	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
EAG14_RS04945	COG1185	polyribonucleotide nucleotidyltransferase activity
EAG14_RS04950	COG3321	synthase
EAG14_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS04950	COG0604	alcohol dehydrogenase
EAG14_RS04955	COG0149	triose-phosphate isomerase activity
EAG14_RS04970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_RS04975	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_RS04980	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_RS04985	COG0649	NAD binding
EAG14_RS04990	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EAG14_RS04995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EAG14_RS05000	COG1034	ATP synthesis coupled electron transport
EAG14_RS05005	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
EAG14_RS05010	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EAG14_RS05020	COG0713	ATP synthesis coupled electron transport
EAG14_RS05035	COG1007	ATP synthesis coupled electron transport
EAG14_RS05050	COG0840	transmembrane signaling receptor activity
EAG14_RS05080	COG0071	Belongs to the small heat shock protein (HSP20) family
EAG14_RS05090	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
EAG14_RS05095	COG2814	Major facilitator Superfamily
EAG14_RS05110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAG14_RS05115	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_RS05120	COG0583	DNA-binding transcription factor activity
EAG14_RS05125	COG1473	amidohydrolase
EAG14_RS05135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EAG14_RS05140	COG0586	Pfam SNARE associated Golgi protein
EAG14_RS05150	COG0860	N-Acetylmuramoyl-L-alanine amidase
EAG14_RS05155	COG0802	atpase or kinase
EAG14_RS05160	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EAG14_RS05170	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS05175	COG4974	Belongs to the 'phage' integrase family
EAG14_RS05180	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS05190	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
EAG14_RS05195	COG2833	Protein of unknown function (DUF455)
EAG14_RS05205	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EAG14_RS05220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EAG14_RS05225	COG0148	phosphopyruvate hydratase activity
EAG14_RS05235	COG2877	3-deoxy-8-phosphooctulonate synthase activity
EAG14_RS05240	COG0504	CTP synthase activity
EAG14_RS05245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EAG14_RS05250	COG0756	dUTP diphosphatase activity
EAG14_RS05260	COG1047	Peptidyl-prolyl cis-trans
EAG14_RS05265	COG2850	peptidyl-arginine hydroxylation
EAG14_RS05280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EAG14_RS05285	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EAG14_RS05290	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EAG14_RS05310	COG0741	lytic transglycosylase activity
EAG14_RS05330	COG2308	Evidence 4 Homologs of previously reported genes of
EAG14_RS05340	COG4628	conserved protein (DUF2132)
EAG14_RS05350	COG0657	acetylesterase activity
EAG14_RS05395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EAG14_RS05405	COG4774	siderophore transport
EAG14_RS05410	COG4774	siderophore transport
EAG14_RS05440	COG0501	Belongs to the peptidase M48B family
EAG14_RS05480	COG3634	alkyl hydroperoxide reductase activity
EAG14_RS05485	COG4771	TonB-dependent receptor
EAG14_RS05495	COG3720	iron ion transport
EAG14_RS05500	COG4558	Periplasmic binding protein
EAG14_RS05505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAG14_RS05510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAG14_RS05520	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
EAG14_RS05535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EAG14_RS05555	COG0583	DNA-binding transcription factor activity
EAG14_RS05560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_RS05565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_RS05575	COG0840	transmembrane signaling receptor activity
EAG14_RS05605	COG1477	protein flavinylation
EAG14_RS05610	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EAG14_RS05620	COG0358	DNA primase activity
EAG14_RS05625	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS05635	COG3540	Alkaline phosphatase
EAG14_RS05645	COG3321	synthase
EAG14_RS05645	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS05645	COG0604	alcohol dehydrogenase
EAG14_RS05650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EAG14_RS05670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EAG14_RS05680	COG0105	UTP biosynthetic process
EAG14_RS05685	COG0820	rRNA (adenine-C2-)-methyltransferase activity
EAG14_RS05700	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
EAG14_RS05705	COG0124	histidyl-tRNA synthetase
EAG14_RS05715	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EAG14_RS05720	COG1160	GTP binding
EAG14_RS05725	COG1923	regulation of RNA biosynthetic process
EAG14_RS05730	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EAG14_RS05735	COG0330	HflC and HflK could
EAG14_RS05740	COG0330	HflC and HflK could
EAG14_RS05745	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
EAG14_RS05750	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EAG14_RS05755	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EAG14_RS05785	COG1187	pseudouridine synthase activity
EAG14_RS05815	COG0174	glutamine synthetase
EAG14_RS05825	COG3852	Histidine kinase
EAG14_RS05830	COG2204	response regulator
EAG14_RS05835	COG0708	Exodeoxyribonuclease III
EAG14_RS05845	COG0277	FAD linked oxidase domain protein
EAG14_RS05860	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
EAG14_RS05875	COG1595	DNA-templated transcription, initiation
EAG14_RS05880	COG3712	iron ion homeostasis
EAG14_RS05890	COG1175	transmembrane transport
EAG14_RS05895	COG0395	ABC-type sugar transport system, permease component
EAG14_RS05900	COG3842	ATPase activity
EAG14_RS05905	COG0246	Mannitol dehydrogenase
EAG14_RS05910	COG2207	Transcriptional regulator
EAG14_RS05915	COG1070	Carbohydrate kinase
EAG14_RS05960	COG0277	FAD linked oxidase domain protein
EAG14_RS05970	COG1295	ribonuclease BN
EAG14_RS05985	COG2267	carboxylic ester hydrolase activity
EAG14_RS06005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
EAG14_RS06010	COG2814	Major facilitator Superfamily
EAG14_RS06020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
EAG14_RS06025	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
EAG14_RS06030	COG0741	lytic transglycosylase activity
EAG14_RS06040	COG0456	acetyltransferase
EAG14_RS06055	COG0557	exoribonuclease II activity
EAG14_RS06060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EAG14_RS06060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EAG14_RS06065	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_RS06075	COG0052	Belongs to the universal ribosomal protein uS2 family
EAG14_RS06080	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
EAG14_RS06090	COG0233	cytoplasmic translational termination
EAG14_RS06100	COG0575	Belongs to the CDS family
EAG14_RS06105	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
EAG14_RS06110	COG0750	zinc metalloprotease
EAG14_RS06125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_RS06130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EAG14_RS06135	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_RS06140	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_RS06145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EAG14_RS06150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAG14_RS06155	COG0505	Belongs to the CarA family
EAG14_RS06165	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EAG14_RS06170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_RS06185	COG1534	Rna-binding protein
EAG14_RS06190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
EAG14_RS06195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EAG14_RS06205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EAG14_RS06250	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EAG14_RS06255	COG0573	inorganic phosphate transmembrane transporter activity
EAG14_RS06260	COG0581	inorganic phosphate transmembrane transporter activity
EAG14_RS06265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EAG14_RS06270	COG0704	Plays a role in the regulation of phosphate uptake
EAG14_RS06275	COG0745	RESPONSE REGULATOR receiver
EAG14_RS06285	COG0534	Mate efflux family protein
EAG14_RS06295	COG0254	rRNA binding
EAG14_RS06300	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EAG14_RS06335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EAG14_RS06340	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
EAG14_RS06345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EAG14_RS06365	COG0741	lytic transglycosylase activity
EAG14_RS06365	COG1388	LysM domain
EAG14_RS06370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS06380	COG0328	RNA-DNA hybrid ribonuclease activity
EAG14_RS06390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAG14_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS06440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EAG14_RS06455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
EAG14_RS06470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_RS06475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_RS06490	COG0322	excinuclease ABC activity
EAG14_RS06500	COG0776	regulation of translation
EAG14_RS06510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_RS06530	COG0513	Belongs to the DEAD box helicase family
EAG14_RS06535	COG0488	(ABC) transporter
EAG14_RS06550	COG3191	aminopeptidase activity
EAG14_RS06570	COG2132	Multicopper oxidase
EAG14_RS06595	COG0789	Transcriptional regulator
EAG14_RS06625	COG0582	viral genome integration into host DNA
EAG14_RS06690	COG2816	NAD+ diphosphatase activity
EAG14_RS06695	COG0425	Belongs to the sulfur carrier protein TusA family
EAG14_RS06700	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EAG14_RS06705	COG0525	valine-tRNA ligase activity
EAG14_RS06730	COG1793	dna ligase
EAG14_RS06740	COG4166	transmembrane transport
EAG14_RS06745	COG4174	ABC transporter (Permease)
EAG14_RS06760	COG4239	(ABC) transporter, permease
EAG14_RS06775	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
EAG14_RS06790	COG0583	DNA-binding transcription factor activity
EAG14_RS06795	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS06800	COG0596	Alpha beta hydrolase
EAG14_RS06810	COG0066	3-isopropylmalate dehydratase activity
EAG14_RS06860	COG1609	Transcriptional regulator
EAG14_RS06875	COG0583	DNA-binding transcription factor activity
EAG14_RS06895	COG1063	alcohol dehydrogenase
EAG14_RS06900	COG3634	alkyl hydroperoxide reductase activity
EAG14_RS06905	COG1959	2 iron, 2 sulfur cluster binding
EAG14_RS06925	COG0477	Major facilitator Superfamily
EAG14_RS06930	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_RS06935	COG3185	4-Hydroxyphenylpyruvate dioxygenase
EAG14_RS06935	COG1082	Xylose isomerase domain protein TIM barrel
EAG14_RS06940	COG2863	cytochrome
EAG14_RS06955	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EAG14_RS06960	COG0779	Required for maturation of 30S ribosomal subunits
EAG14_RS06965	COG0195	Participates in both transcription termination and antitermination
EAG14_RS06970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
EAG14_RS06975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
EAG14_RS06980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EAG14_RS06985	COG1217	gtp-binding protein TYPA
EAG14_RS06995	COG1024	Enoyl-CoA hydratase
EAG14_RS07000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
EAG14_RS07005	COG2867	negative regulation of translational initiation
EAG14_RS07010	COG2914	Belongs to the UPF0125 (RnfH) family
EAG14_RS07035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAG14_RS07035	COG0519	Catalyzes the synthesis of GMP from XMP
EAG14_RS07080	COG0506	proline dehydrogenase activity
EAG14_RS07080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAG14_RS07080	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EAG14_RS07095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EAG14_RS07105	COG3193	protein, possibly involved in utilization of glycolate and propanediol
EAG14_RS07145	COG3128	pkhd-type hydroxylase
EAG14_RS07150	COG4774	siderophore transport
EAG14_RS07175	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
EAG14_RS07180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
EAG14_RS07185	COG0291	Belongs to the bacterial ribosomal protein bL35 family
EAG14_RS07190	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
EAG14_RS07195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
EAG14_RS07200	COG0072	phenylalanine-tRNA ligase activity
EAG14_RS07200	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_RS07205	COG0776	regulation of translation
EAG14_RS07210	COG0789	Transcriptional regulator
EAG14_RS07240	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
EAG14_RS07245	COG0308	aminopeptidase N
EAG14_RS07250	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EAG14_RS07260	COG2267	carboxylic ester hydrolase activity
EAG14_RS07265	COG2207	Transcriptional regulator
EAG14_RS07270	COG4638	Rieske (2fe-2S)
EAG14_RS07275	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EAG14_RS07280	COG2146	nitrite reductase [NAD(P)H] activity
EAG14_RS07290	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS07315	COG0667	Aldo Keto reductase
EAG14_RS07325	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS07330	COG0583	DNA-binding transcription factor activity
EAG14_RS07335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EAG14_RS07340	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
EAG14_RS07355	COG1666	GTP binding
EAG14_RS07360	COG0812	UDP-N-acetylmuramate dehydrogenase activity
EAG14_RS07365	COG2198	Histidine kinase
EAG14_RS07365	COG2205	protein histidine kinase activity
EAG14_RS07365	COG0784	Response regulator, receiver
EAG14_RS07375	COG0137	argininosuccinate synthase activity
EAG14_RS07380	COG3123	guanosine phosphorylase activity
EAG14_RS07390	COG1393	Belongs to the ArsC family
EAG14_RS07395	COG0285	dihydrofolate synthase activity
EAG14_RS07415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_RS07460	COG1840	ABC-type Fe3 transport system, periplasmic component
EAG14_RS07465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EAG14_RS07500	COG2204	response regulator
EAG14_RS07520	COG4177	L-phenylalanine transmembrane transporter activity
EAG14_RS07555	COG1574	metal-dependent hydrolase with the TIM-barrel fold
EAG14_RS07565	COG1335	isochorismatase
EAG14_RS07570	COG1741	Belongs to the pirin family
EAG14_RS07575	COG0583	DNA-binding transcription factor activity
EAG14_RS07580	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EAG14_RS07595	COG0415	Belongs to the DNA photolyase family
EAG14_RS07600	COG3046	protein related to deoxyribodipyrimidine photolyase
EAG14_RS07615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_RS07620	COG0024	Methionine aminopeptidase
EAG14_RS07630	COG3339	Conserved Protein
EAG14_RS07645	COG1067	ATP-dependent peptidase activity
EAG14_RS07650	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
EAG14_RS07655	COG1011	Hydrolase
EAG14_RS07670	COG1253	flavin adenine dinucleotide binding
EAG14_RS07680	COG0642	Histidine kinase
EAG14_RS07705	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
EAG14_RS07710	COG1562	ergosterol biosynthetic process
EAG14_RS07720	COG1760	l-serine dehydratase
EAG14_RS07725	COG1562	ergosterol biosynthetic process
EAG14_RS07745	COG0544	peptidyl-prolyl cis-trans isomerase activity
EAG14_RS07750	COG0740	serine-type endopeptidase activity
EAG14_RS07755	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
EAG14_RS07760	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAG14_RS07790	COG1451	nucleotide metabolic process
EAG14_RS07795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EAG14_RS07805	COG0114	fumarate hydratase activity
EAG14_RS07815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAG14_RS07825	COG4654	Cytochrome c, class I
EAG14_RS07835	COG0129	dihydroxy-acid dehydratase activity
EAG14_RS07845	COG4774	siderophore transport
EAG14_RS07850	COG3712	iron ion homeostasis
EAG14_RS07860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
EAG14_RS07875	COG1802	Transcriptional regulator
EAG14_RS07895	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS07905	COG0583	DNA-binding transcription factor activity
EAG14_RS07910	COG0402	S-adenosylhomocysteine deaminase activity
EAG14_RS07920	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS07930	COG1137	ATPase activity
EAG14_RS07955	COG3278	Belongs to the heme-copper respiratory oxidase family
EAG14_RS07990	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_RS08005	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EAG14_RS08015	COG0730	response to heat
EAG14_RS08030	COG4206	TonB-dependent receptor
EAG14_RS08045	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
EAG14_RS08050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EAG14_RS08055	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EAG14_RS08060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
EAG14_RS08065	COG0778	Nitroreductase
EAG14_RS08070	COG1611	Belongs to the LOG family
EAG14_RS08075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EAG14_RS08110	COG1320	monovalent cation:proton antiporter activity
EAG14_RS08115	COG2212	antiporter activity
EAG14_RS08120	COG1863	multisubunit Na H antiporter MnhE subunit
EAG14_RS08125	COG0651	ATP synthesis coupled electron transport
EAG14_RS08130	COG1006	Multisubunit Na H antiporter MnhC subunit
EAG14_RS08135	COG2111	Na H antiporter
EAG14_RS08135	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EAG14_RS08145	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EAG14_RS08155	COG0776	regulation of translation
EAG14_RS08165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EAG14_RS08170	COG0287	Prephenate dehydrogenase
EAG14_RS08175	COG1605	Chorismate mutase
EAG14_RS08175	COG0077	Prephenate dehydratase
EAG14_RS08180	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
EAG14_RS08195	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EAG14_RS08200	COG0546	phosphoglycolate phosphatase activity
EAG14_RS08265	COG2197	response regulator
EAG14_RS08270	COG4585	Histidine kinase
EAG14_RS08280	COG0123	including yeast histone deacetylase and acetoin utilization protein
EAG14_RS08290	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAG14_RS08325	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EAG14_RS08340	COG1492	cobalamin metabolic process
EAG14_RS08345	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EAG14_RS08365	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_RS08375	COG1802	Transcriptional regulator
EAG14_RS08390	COG3654	unkown
EAG14_RS08395	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EAG14_RS08400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS08405	COG2900	Belongs to the SlyX family
EAG14_RS08420	COG0513	Belongs to the DEAD box helicase family
EAG14_RS08430	COG0023	Translation Initiation Factor
EAG14_RS08445	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
EAG14_RS08450	COG1959	2 iron, 2 sulfur cluster binding
EAG14_RS08460	COG0560	Phosphoserine phosphatase
EAG14_RS08470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_RS08490	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EAG14_RS08495	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
EAG14_RS08495	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EAG14_RS08500	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
EAG14_RS08540	COG0746	molybdenum cofactor guanylyltransferase activity
EAG14_RS08545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EAG14_RS08570	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS08575	COG3039	Transposase
EAG14_RS08600	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EAG14_RS08620	COG0347	Belongs to the P(II) protein family
EAG14_RS08630	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EAG14_RS08650	COG1595	DNA-templated transcription, initiation
EAG14_RS08655	COG0028	Belongs to the TPP enzyme family
EAG14_RS08660	COG0440	acetolactate synthase activity
EAG14_RS08665	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
EAG14_RS08670	COG1183	phosphatidylcholine synthase activity
EAG14_RS08675	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_RS08685	COG1414	Transcriptional regulator
EAG14_RS08690	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
EAG14_RS08695	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EAG14_RS08710	COG2832	Protein of unknown function (DUF454)
EAG14_RS08720	COG0826	peptidase U32
EAG14_RS08760	COG1619	proteins homologs of microcin C7 resistance protein MccF
EAG14_RS08770	COG0242	peptide deformylase activity
EAG14_RS08775	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
EAG14_RS08790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EAG14_RS08790	COG0047	phosphoribosylformylglycinamidine synthase activity
EAG14_RS08805	COG3047	cAMP biosynthetic process
EAG14_RS08900	COG1538	Outer membrane efflux protein
EAG14_RS08910	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EAG14_RS08925	COG1309	transcriptional regulator
EAG14_RS08930	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAG14_RS08940	COG0577	efflux transmembrane transporter activity
EAG14_RS08940	COG1136	(ABC) transporter
EAG14_RS08990	COG1024	Enoyl-CoA hydratase
EAG14_RS08995	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS09010	COG2022	thiamine diphosphate biosynthetic process
EAG14_RS09025	COG0351	phosphomethylpyrimidine kinase
EAG14_RS09035	COG0564	pseudouridine synthase activity
EAG14_RS09040	COG0840	transmembrane signaling receptor activity
EAG14_RS09050	COG2183	response to ionizing radiation
EAG14_RS09085	COG0657	acetylesterase activity
EAG14_RS09100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EAG14_RS09105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EAG14_RS09110	COG0470	DNA polymerase III
EAG14_RS09120	COG0084	hydrolase, TatD family'
EAG14_RS09130	COG1132	(ABC) transporter
EAG14_RS09135	COG0823	Involved in the tonB-independent uptake of proteins
EAG14_RS09140	COG2885	chlorophyll binding
EAG14_RS09150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EAG14_RS09160	COG0217	transcriptional regulatory protein
EAG14_RS09165	COG0484	heat shock protein binding
EAG14_RS09190	COG3706	GGDEF domain
EAG14_RS09200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS09205	COG0842	Transport permease protein
EAG14_RS09205	COG1129	ABC transporter
EAG14_RS09210	COG0842	Transport permease protein
EAG14_RS09215	COG0402	S-adenosylhomocysteine deaminase activity
EAG14_RS09225	COG1079	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS09230	COG4603	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS09235	COG3845	ABC transporter
EAG14_RS09245	COG1744	ABC transporter substrate-binding protein PnrA-like
EAG14_RS09255	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
EAG14_RS09270	COG0765	amino acid transport
EAG14_RS09285	COG0433	COG0433 Predicted ATPase
EAG14_RS09290	COG0217	transcriptional regulatory protein
EAG14_RS09295	COG0151	Belongs to the GarS family
EAG14_RS09300	COG0408	coproporphyrinogen oxidase activity
EAG14_RS09305	COG0799	negative regulation of ribosome biogenesis
EAG14_RS09310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
EAG14_RS09315	COG0424	maF-like protein
EAG14_RS09325	COG0625	glutathione transferase activity
EAG14_RS09335	COG0745	RESPONSE REGULATOR receiver
EAG14_RS09340	COG2205	protein histidine kinase activity
EAG14_RS09345	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
EAG14_RS09350	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EAG14_RS09355	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EAG14_RS09385	COG0436	Aminotransferase
EAG14_RS09390	COG0583	DNA-binding transcription factor activity
EAG14_RS09410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
EAG14_RS09430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EAG14_RS09435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EAG14_RS09440	COG0252	asparaginase activity
EAG14_RS09445	COG0563	adenylate kinase activity
EAG14_RS09450	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
EAG14_RS09455	COG2835	tetraacyldisaccharide 4'-kinase activity
EAG14_RS09460	COG1663	tetraacyldisaccharide 4'-kinase activity
EAG14_RS09460	COG2835	tetraacyldisaccharide 4'-kinase activity
EAG14_RS09465	COG0848	biopolymer transport protein
EAG14_RS09470	COG0811	peptide transport
EAG14_RS09475	COG1570	exodeoxyribonuclease VII activity
EAG14_RS09495	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
EAG14_RS09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS09510	COG0747	negative chemotaxis
EAG14_RS09555	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS09600	COG2814	Major facilitator Superfamily
EAG14_RS09605	COG1566	PFAM secretion protein HlyD family protein
EAG14_RS09610	COG1538	Outer membrane efflux protein
EAG14_RS09620	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
EAG14_RS09625	COG0583	DNA-binding transcription factor activity
EAG14_RS09645	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS09650	COG2706	6-phosphogluconolactonase activity
EAG14_RS09680	COG0492	ferredoxin-NADP+ reductase activity
EAG14_RS09685	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EAG14_RS09690	COG0529	Catalyzes the synthesis of activated sulfate
EAG14_RS09690	COG2895	sulfate adenylyltransferase (ATP) activity
EAG14_RS09695	COG0175	sulfate reduction
EAG14_RS09700	COG0175	sulfate reduction
EAG14_RS09715	COG0730	response to heat
EAG14_RS09725	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
EAG14_RS09730	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAG14_RS09735	COG0431	NADPH-dependent FMN reductase
EAG14_RS09740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS09745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS09760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS09765	COG1116	anion transmembrane transporter activity
EAG14_RS09775	COG1309	transcriptional regulator
EAG14_RS09780	COG0604	alcohol dehydrogenase
EAG14_RS09800	COG0259	pyridoxamine-phosphate oxidase activity
EAG14_RS09805	COG1309	transcriptional regulator
EAG14_RS09855	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_RS09860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
EAG14_RS09870	COG2032	superoxide dismutase activity
EAG14_RS09885	COG0587	DNA-directed DNA polymerase activity
EAG14_RS09895	COG1196	nuclear chromosome segregation
EAG14_RS09905	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EAG14_RS09910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_RS09955	COG0183	Belongs to the thiolase family
EAG14_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS09965	COG0488	(ABC) transporter
EAG14_RS09970	COG2890	protein-(glutamine-N5) methyltransferase activity
EAG14_RS09975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
EAG14_RS09985	COG2171	N-acyltransferase activity
EAG14_RS09990	COG0436	Aminotransferase
EAG14_RS09995	COG0840	transmembrane signaling receptor activity
EAG14_RS10000	COG2878	Part of a membrane complex involved in electron transport
EAG14_RS10020	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAG14_RS10030	COG1522	sequence-specific DNA binding
EAG14_RS10040	COG1022	Amp-dependent synthetase and ligase
EAG14_RS10045	COG1802	Transcriptional regulator
EAG14_RS10050	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAG14_RS10050	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
EAG14_RS10060	COG1703	isobutyryl-CoA mutase activity
EAG14_RS10065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EAG14_RS10075	COG4770	biotin carboxylase activity
EAG14_RS10100	COG3437	response regulator, receiver
EAG14_RS10130	COG0640	Transcriptional regulator
EAG14_RS10145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS10145	COG3453	Protein conserved in bacteria
EAG14_RS10205	COG1191	sigma factor activity
EAG14_RS10235	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EAG14_RS10250	COG1157	protein secretion by the type III secretion system
EAG14_RS10275	COG1677	Flagellar hook-basal body complex protein FliE
EAG14_RS10280	COG1558	bacterial-type flagellum-dependent cell motility
EAG14_RS10290	COG1706	bacterial-type flagellum-dependent cell motility
EAG14_RS10295	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
EAG14_RS10310	COG4786	Flagellar basal body rod
EAG14_RS10315	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_RS10320	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EAG14_RS10325	COG1684	flagellar biosynthetic protein fliR
EAG14_RS10330	COG1987	bacterial-type flagellum assembly
EAG14_RS10335	COG3591	Belongs to the peptidase S1B family
EAG14_RS10335	COG1864	DNA RNA non-specific endonuclease
EAG14_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS10435	COG0534	Mate efflux family protein
EAG14_RS10460	COG0346	lactoylglutathione lyase activity
EAG14_RS10470	COG0791	NLP P60 protein
EAG14_RS10530	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EAG14_RS10540	COG0517	IMP dehydrogenase activity
EAG14_RS10540	COG0516	GMP reductase activity
EAG14_RS10565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAG14_RS10570	COG0494	nUDIX hydrolase
EAG14_RS10580	COG1349	DNA-binding transcription factor activity
EAG14_RS10585	COG0583	DNA-binding transcription factor activity
EAG14_RS10590	COG0697	spore germination
EAG14_RS10600	COG5000	phosphorelay sensor kinase activity
EAG14_RS10610	COG1090	epimerase
EAG14_RS10630	COG0527	aspartate kinase activity
EAG14_RS10650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAG14_RS10655	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAG14_RS10660	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EAG14_RS10670	COG4566	intracellular signal transduction
EAG14_RS10675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EAG14_RS10690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EAG14_RS10695	COG0167	dihydroorotate dehydrogenase activity
EAG14_RS10715	COG0579	oxidoreductase
EAG14_RS10745	COG0443	Heat shock 70 kDa protein
EAG14_RS10765	COG1104	cysteine desulfurase activity
EAG14_RS10770	COG1959	2 iron, 2 sulfur cluster binding
EAG14_RS10775	COG0556	nucleotide-excision repair
EAG14_RS10790	COG3384	dioxygenase
EAG14_RS10795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_RS10850	COG4608	Belongs to the ABC transporter superfamily
EAG14_RS10855	COG0444	Belongs to the ABC transporter superfamily
EAG14_RS10860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS10865	COG0601	transmembrane transport
EAG14_RS10870	COG2072	flavoprotein involved in K transport
EAG14_RS10880	COG1739	Uncharacterized protein family UPF0029
EAG14_RS10895	COG0154	amidase activity
EAG14_RS10900	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS10905	COG3048	D-serine ammonia-lyase activity
EAG14_RS10945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EAG14_RS10950	COG4181	ATPase activity
EAG14_RS10970	COG0626	cystathionine gamma-synthase activity
EAG14_RS10995	COG1054	Belongs to the UPF0176 family
EAG14_RS11000	COG1741	Belongs to the pirin family
EAG14_RS11010	COG1741	Belongs to the pirin family
EAG14_RS11015	COG0583	DNA-binding transcription factor activity
EAG14_RS11025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_RS11030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EAG14_RS11035	COG3706	GGDEF domain
EAG14_RS11060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EAG14_RS11065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS11080	COG1054	Belongs to the UPF0176 family
EAG14_RS11090	COG3706	GGDEF domain
EAG14_RS11095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
EAG14_RS11100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAG14_RS11105	COG4208	sulfate ABC transporter
EAG14_RS11115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EAG14_RS11125	COG0450	alkyl hydroperoxide reductase
EAG14_RS11130	COG0840	transmembrane signaling receptor activity
EAG14_RS11135	COG0700	Nucleoside recognition
EAG14_RS11165	COG2925	Exonuclease
EAG14_RS11170	COG2951	lytic endotransglycosylase activity
EAG14_RS11185	COG1301	dicarboxylic acid transport
EAG14_RS11190	COG0542	response to heat
EAG14_RS11195	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EAG14_RS11210	COG1199	ATP-dependent helicase activity
EAG14_RS11225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EAG14_RS11230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EAG14_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
EAG14_RS11240	COG0567	Dehydrogenase, E1 component
EAG14_RS11260	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS11265	COG1643	Atp-dependent helicase
EAG14_RS11280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAG14_RS11280	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
EAG14_RS11290	COG0583	DNA-binding transcription factor activity
EAG14_RS11295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EAG14_RS11305	COG5001	Diguanylate cyclase
EAG14_RS11305	COG3300	MHYT domain
EAG14_RS11325	COG4651	solute:proton antiporter activity
EAG14_RS11325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EAG14_RS11335	COG2011	ABC-type metal ion transport system permease component
EAG14_RS11340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EAG14_RS11345	COG2814	Major facilitator Superfamily
EAG14_RS11350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EAG14_RS11365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_RS11395	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS11405	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS11405	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_RS11410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EAG14_RS11415	COG0509	glycine decarboxylation via glycine cleavage system
EAG14_RS11420	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAG14_RS11420	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
EAG14_RS11425	COG0494	nUDIX hydrolase
EAG14_RS11430	COG0545	Peptidyl-prolyl cis-trans isomerase
EAG14_RS11435	COG0789	Transcriptional regulator
EAG14_RS11455	COG0564	pseudouridine synthase activity
EAG14_RS11465	COG2197	response regulator
EAG14_RS11470	COG3916	Acyl-homoserine-lactone synthase
EAG14_RS11475	COG0529	Catalyzes the synthesis of activated sulfate
EAG14_RS11490	COG0840	transmembrane signaling receptor activity
EAG14_RS11495	COG0697	spore germination
EAG14_RS11500	COG1846	Transcriptional regulator
EAG14_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS11510	COG0183	Belongs to the thiolase family
EAG14_RS11520	COG0589	response to stress
EAG14_RS11530	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
EAG14_RS11550	COG2851	Citrate transporter
EAG14_RS11555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS11565	COG3842	ATPase activity
EAG14_RS11575	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_RS11580	COG1177	transmembrane transport
EAG14_RS11585	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS11660	COG2153	protein acetylation
EAG14_RS11665	COG2130	NADP-dependent
EAG14_RS11680	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS11685	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS11690	COG0183	Belongs to the thiolase family
EAG14_RS11695	COG1024	Enoyl-CoA hydratase
EAG14_RS11695	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS11700	COG4716	Myosin-crossreactive antigen
EAG14_RS11710	COG0411	ABC transporter
EAG14_RS11730	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS11735	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EAG14_RS11740	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
EAG14_RS11745	COG2917	probably involved in intracellular septation
EAG14_RS11755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_RS11770	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EAG14_RS11780	COG0688	phosphatidylethanolamine metabolic process
EAG14_RS11800	COG1228	amidohydrolase
EAG14_RS11810	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
EAG14_RS11815	COG2986	histidine ammonia-lyase
EAG14_RS11830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS11835	COG2358	TRAP transporter, solute receptor (TAXI family
EAG14_RS11840	COG2205	protein histidine kinase activity
EAG14_RS11845	COG0745	RESPONSE REGULATOR receiver
EAG14_RS11870	COG0037	tRNA processing
EAG14_RS11875	COG0825	malonyl-CoA metabolic process
EAG14_RS11885	COG0215	cysteine-tRNA ligase activity
EAG14_RS11910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EAG14_RS11915	COG3228	Belongs to the MtfA family
EAG14_RS11925	COG1522	sequence-specific DNA binding
EAG14_RS11950	COG3384	dioxygenase
EAG14_RS11965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EAG14_RS12025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS12050	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
EAG14_RS12150	COG0564	pseudouridine synthase activity
EAG14_RS12185	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS12195	COG0633	Ferredoxin
EAG14_RS12205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
EAG14_RS12210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_RS12215	COG0436	Aminotransferase
EAG14_RS12220	COG0824	Thioesterase
EAG14_RS12270	COG0039	L-malate dehydrogenase activity
EAG14_RS12275	COG2188	Transcriptional regulator
EAG14_RS12295	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EAG14_RS12300	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EAG14_RS12305	COG0372	Belongs to the citrate synthase family
EAG14_RS12330	COG2194	sulfuric ester hydrolase activity
EAG14_RS12340	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS12345	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_RS12355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS12360	COG0601	transmembrane transport
EAG14_RS12370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS12390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_RS12400	COG1522	sequence-specific DNA binding
EAG14_RS12440	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAG14_RS12445	COG0583	DNA-binding transcription factor activity
EAG14_RS12460	COG0667	Aldo Keto reductase
EAG14_RS12480	COG0840	transmembrane signaling receptor activity
EAG14_RS12490	COG1473	amidohydrolase
EAG14_RS12510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS12515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EAG14_RS12530	COG1271	oxidase subunit
EAG14_RS12535	COG1294	oxidase, subunit
EAG14_RS12545	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS12575	COG0714	Associated with various cellular activities
EAG14_RS12590	COG2951	lytic endotransglycosylase activity
EAG14_RS12595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS12605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS12610	COG1126	abc transporter atp-binding protein
EAG14_RS12620	COG1473	amidohydrolase
EAG14_RS12625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS12630	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EAG14_RS12635	COG0683	leucine binding
EAG14_RS12645	COG0577	efflux transmembrane transporter activity
EAG14_RS12645	COG1136	(ABC) transporter
EAG14_RS12650	COG1136	(ABC) transporter
EAG14_RS12650	COG0577	efflux transmembrane transporter activity
EAG14_RS12655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS12660	COG1538	Outer membrane efflux protein
EAG14_RS12670	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS12675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
EAG14_RS12690	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EAG14_RS12695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS12700	COG1116	anion transmembrane transporter activity
EAG14_RS12705	COG0840	transmembrane signaling receptor activity
EAG14_RS12710	COG0517	IMP dehydrogenase activity
EAG14_RS12715	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS12720	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS12725	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_RS12730	COG3265	gluconokinase activity
EAG14_RS12735	COG1609	Transcriptional regulator
EAG14_RS12755	COG0840	transmembrane signaling receptor activity
EAG14_RS12760	COG2223	nitrite transmembrane transporter activity
EAG14_RS12765	COG2815	serine threonine protein kinase
EAG14_RS12765	COG0515	serine threonine protein kinase
EAG14_RS12770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EAG14_RS12785	COG0243	molybdopterin cofactor binding
EAG14_RS12790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EAG14_RS12800	COG5297	Belongs to the glycosyl hydrolase family 6
EAG14_RS12800	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
EAG14_RS12805	COG1607	acyl-coa hydrolase
EAG14_RS12830	COG0828	Belongs to the bacterial ribosomal protein bS21 family
EAG14_RS12845	COG0583	DNA-binding transcription factor activity
EAG14_RS12885	COG2721	sulfolactate sulfo-lyase activity
EAG14_RS12915	COG0312	modulator of DNA gyrase
EAG14_RS12920	COG3028	Belongs to the UPF0307 family
EAG14_RS12925	COG0521	Mo-molybdopterin cofactor biosynthetic process
EAG14_RS12935	COG1045	serine acetyltransferase
EAG14_RS12945	COG0483	inositol monophosphate 1-phosphatase activity
EAG14_RS12960	COG5001	Diguanylate cyclase
EAG14_RS12965	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
EAG14_RS12990	COG5001	Diguanylate cyclase
EAG14_RS13000	COG1968	undecaprenyl-diphosphatase activity
EAG14_RS13015	COG2972	Histidine kinase
EAG14_RS13030	COG5001	Diguanylate cyclase
EAG14_RS13030	COG5002	protein histidine kinase activity
EAG14_RS13030	COG3447	MASE1 domain protein
EAG14_RS13060	COG1280	lysine exporter protein (LysE YggA)
EAG14_RS13065	COG4133	protoheme IX ABC transporter activity
EAG14_RS13075	COG1234	tRNA 3'-trailer cleavage
EAG14_RS13085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS13085	COG2205	protein histidine kinase activity
EAG14_RS13095	COG0745	RESPONSE REGULATOR receiver
EAG14_RS13115	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
EAG14_RS13115	COG3608	succinylglutamate desuccinylase aspartoacylase
EAG14_RS13150	COG3284	Transcriptional regulator
EAG14_RS13175	COG0655	NAD(P)H dehydrogenase (quinone) activity
EAG14_RS13195	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EAG14_RS13230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
EAG14_RS13240	COG1910	domain protein
EAG14_RS13250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS13255	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
EAG14_RS13260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
EAG14_RS13270	COG1722	exodeoxyribonuclease VII activity
EAG14_RS13310	COG3300	MHYT domain
EAG14_RS13310	COG5001	Diguanylate cyclase
EAG14_RS13320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
EAG14_RS13325	COG0181	hydroxymethylbilane synthase activity
EAG14_RS13375	COG0583	DNA-binding transcription factor activity
EAG14_RS13380	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS13400	COG2326	polyphosphate kinase activity
EAG14_RS13420	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS13425	COG0129	dihydroxy-acid dehydratase activity
EAG14_RS13435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_RS13440	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS13445	COG0277	FAD linked oxidase domain protein
EAG14_RS13450	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS13455	COG0179	Fumarylacetoacetate (FAA) hydrolase
EAG14_RS13460	COG0784	Response regulator, receiver
EAG14_RS13460	COG0835	chemotaxis
EAG14_RS13495	COG0617	tRNA 3'-terminal CCA addition
EAG14_RS13505	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAG14_RS13510	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
EAG14_RS13560	COG0728	peptidoglycan biosynthetic process
EAG14_RS13565	COG0268	Binds directly to 16S ribosomal RNA
EAG14_RS13575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EAG14_RS13580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAG14_RS13640	COG0642	Histidine kinase
EAG14_RS13650	COG0840	transmembrane signaling receptor activity
EAG14_RS13660	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
EAG14_RS13670	COG3483	tryptophan 2,3-dioxygenase activity
EAG14_RS13715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
EAG14_RS13720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_RS13725	COG5001	Diguanylate cyclase
EAG14_RS13735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EAG14_RS13740	COG2916	Histone family protein nucleoid-structuring protein H-NS
EAG14_RS13745	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EAG14_RS13755	COG3245	cytochrome
EAG14_RS13765	COG4263	nitrous-oxide reductase activity
EAG14_RS13770	COG3901	Regulator of nitric oxide reductase transcription
EAG14_RS13770	COG0348	domain, Protein
EAG14_RS13785	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
EAG14_RS13800	COG0513	Belongs to the DEAD box helicase family
EAG14_RS13805	COG2321	neutral zinc metallopeptidase
EAG14_RS13815	COG0717	Belongs to the dCTP deaminase family
EAG14_RS13820	COG0402	S-adenosylhomocysteine deaminase activity
EAG14_RS13830	COG0840	transmembrane signaling receptor activity
EAG14_RS13850	COG4603	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS13855	COG3845	ABC transporter
EAG14_RS13870	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EAG14_RS13875	COG3706	GGDEF domain
EAG14_RS13895	COG5001	Diguanylate cyclase
EAG14_RS13895	COG3300	MHYT domain
EAG14_RS13930	COG0405	Gamma-glutamyltransferase
EAG14_RS13965	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS13975	COG0583	DNA-binding transcription factor activity
EAG14_RS14000	COG1301	dicarboxylic acid transport
EAG14_RS14005	COG0840	transmembrane signaling receptor activity
EAG14_RS14010	COG0281	malic enzyme
EAG14_RS14010	COG0280	phosphate acetyltransferase
EAG14_RS14015	COG1639	'signal transduction protein
EAG14_RS14025	COG1116	anion transmembrane transporter activity
EAG14_RS14030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS14040	COG1752	Esterase of the alpha-beta hydrolase superfamily
EAG14_RS14045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_RS14050	COG2721	sulfolactate sulfo-lyase activity
EAG14_RS14055	COG0246	Mannitol dehydrogenase
EAG14_RS14060	COG1063	alcohol dehydrogenase
EAG14_RS14065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS14075	COG0765	amino acid transport
EAG14_RS14090	COG2186	Transcriptional regulator
EAG14_RS14095	COG2610	gluconate transmembrane transporter activity
EAG14_RS14100	COG2084	Dehydrogenase
EAG14_RS14105	COG3395	kinase activity
EAG14_RS14110	COG0235	Class ii aldolase
EAG14_RS14120	COG3622	Belongs to the hyi family
EAG14_RS14125	COG0829	nickel cation binding
EAG14_RS14130	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EAG14_RS14140	COG0436	Aminotransferase
EAG14_RS14145	COG2814	Major facilitator Superfamily
EAG14_RS14220	COG4770	biotin carboxylase activity
EAG14_RS14225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EAG14_RS14230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
EAG14_RS14235	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
EAG14_RS14270	COG0436	Aminotransferase
EAG14_RS14295	COG0831	urea catabolic process
EAG14_RS14305	COG0832	Belongs to the urease beta subunit family
EAG14_RS14310	COG0804	urea catabolic process
EAG14_RS14315	COG0454	-acetyltransferase
EAG14_RS14320	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
EAG14_RS14325	COG0830	nickel cation binding
EAG14_RS14340	COG0582	viral genome integration into host DNA
EAG14_RS14440	COG4695	Portal protein
EAG14_RS14475	COG1902	pentaerythritol trinitrate reductase activity
EAG14_RS14490	COG2346	COG2346, Truncated hemoglobins
EAG14_RS14495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS14500	COG0765	amino acid transport
EAG14_RS14505	COG0765	amino acid transport
EAG14_RS14515	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EAG14_RS14525	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAG14_RS14545	COG0437	4 iron, 4 sulfur cluster binding
EAG14_RS14550	COG3383	formate dehydrogenase (NAD+) activity
EAG14_RS14550	COG0243	molybdopterin cofactor binding
EAG14_RS14580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EAG14_RS14590	COG0243	molybdopterin cofactor binding
EAG14_RS14595	COG2223	nitrite transmembrane transporter activity
EAG14_RS14600	COG0583	DNA-binding transcription factor activity
EAG14_RS14605	COG0489	protein tyrosine kinase activity
EAG14_RS14620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_RS14620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EAG14_RS14645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EAG14_RS14650	COG0602	queuosine metabolic process
EAG14_RS14655	COG0720	synthase
EAG14_RS14670	COG0156	8-amino-7-oxononanoate synthase activity
EAG14_RS14690	COG0583	DNA-binding transcription factor activity
EAG14_RS14710	COG2205	protein histidine kinase activity
EAG14_RS14720	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EAG14_RS14735	COG4251	negative regulation of phosphorylation
EAG14_RS14735	COG2203	Gaf domain
EAG14_RS14735	COG5001	Diguanylate cyclase
EAG14_RS14735	COG3706	GGDEF domain
EAG14_RS14740	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
EAG14_RS14745	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
EAG14_RS14755	COG0210	DNA helicase
EAG14_RS14765	COG0516	GMP reductase activity
EAG14_RS14775	COG2084	Dehydrogenase
EAG14_RS14840	COG2814	Major facilitator Superfamily
EAG14_RS14845	COG3706	GGDEF domain
EAG14_RS14850	COG0513	Belongs to the DEAD box helicase family
EAG14_RS14855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EAG14_RS14865	COG2154	pterin-4-alpha-carbinolamine dehydratase
EAG14_RS14870	COG1162	GTPase activity
EAG14_RS14875	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
EAG14_RS14885	COG0335	large ribosomal subunit rRNA binding
EAG14_RS14890	COG0336	Belongs to the RNA methyltransferase TrmD family
EAG14_RS14895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EAG14_RS14900	COG0228	four-way junction DNA binding
EAG14_RS14915	COG0306	phosphate transporter
EAG14_RS14920	COG1392	Phosphate transport regulator
EAG14_RS14945	COG0559	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS14950	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EAG14_RS14955	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EAG14_RS14960	COG1674	ftsk spoiiie
EAG14_RS14970	COG0492	ferredoxin-NADP+ reductase activity
EAG14_RS14975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
EAG14_RS14980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EAG14_RS14985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EAG14_RS15000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAG14_RS15000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_RS15030	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EAG14_RS15035	COG3132	Protein of unknown function, DUF480
EAG14_RS15050	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS15055	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS15080	COG5002	protein histidine kinase activity
EAG14_RS15085	COG2264	protein methyltransferase activity
EAG14_RS15090	COG3781	membrane
EAG14_RS15100	COG0196	riboflavin kinase activity
EAG14_RS15110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
EAG14_RS15115	COG1283	sodium-dependent phosphate transmembrane transporter activity
EAG14_RS15120	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EAG14_RS15130	COG0583	DNA-binding transcription factor activity
EAG14_RS15150	COG0697	spore germination
EAG14_RS15165	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS15195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAG14_RS15210	COG0084	hydrolase, TatD family'
EAG14_RS15220	COG1136	(ABC) transporter
EAG14_RS15225	COG4591	ABC-type transport system involved in lipoprotein release permease component
EAG14_RS15235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EAG14_RS15240	COG0840	transmembrane signaling receptor activity
EAG14_RS15245	COG0613	PHP domain protein
EAG14_RS15250	COG0009	L-threonylcarbamoyladenylate synthase
EAG14_RS15255	COG0840	transmembrane signaling receptor activity
EAG14_RS15260	COG1994	Peptidase M50
EAG14_RS15265	COG0180	Tryptophanyl-tRNA synthetase
EAG14_RS15280	COG0745	RESPONSE REGULATOR receiver
EAG14_RS15295	COG3800	Transcriptional regulator
EAG14_RS15295	COG1396	sequence-specific DNA binding
EAG14_RS15315	COG2828	Protein conserved in bacteria
EAG14_RS15325	COG1116	anion transmembrane transporter activity
EAG14_RS15330	COG0395	ABC-type sugar transport system, permease component
EAG14_RS15335	COG1609	Transcriptional regulator
EAG14_RS15350	COG1177	transmembrane transport
EAG14_RS15355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EAG14_RS15395	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
EAG14_RS15400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_RS15405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
EAG14_RS15405	COG0517	IMP dehydrogenase activity
EAG14_RS15405	COG0617	tRNA 3'-terminal CCA addition
EAG14_RS15410	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
EAG14_RS15415	COG1047	Peptidyl-prolyl cis-trans
EAG14_RS15420	COG2003	Belongs to the UPF0758 family
EAG14_RS15425	COG1193	negative regulation of DNA recombination
EAG14_RS15430	COG0737	Belongs to the 5'-nucleotidase family
EAG14_RS15440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EAG14_RS15445	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EAG14_RS15450	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
EAG14_RS15465	COG1561	YicC-like family, N-terminal region
EAG14_RS15470	COG0194	GDP metabolic process
EAG14_RS15475	COG1758	RNA polymerase activity
EAG14_RS15480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EAG14_RS15500	COG1420	regulation of RNA biosynthetic process
EAG14_RS15505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EAG14_RS15510	COG0497	DNA recombination
EAG14_RS15515	COG1660	Displays ATPase and GTPase activities
EAG14_RS15520	COG1194	a g-specific adenine glycosylase
EAG14_RS15530	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
EAG14_RS15545	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
EAG14_RS15555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EAG14_RS15560	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
EAG14_RS15565	COG0193	aminoacyl-tRNA hydrolase activity
EAG14_RS15570	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EAG14_RS15575	COG0601	transmembrane transport
EAG14_RS15580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS15590	COG4608	Belongs to the ABC transporter superfamily
EAG14_RS15595	COG0747	negative chemotaxis
EAG14_RS15600	COG0154	amidase activity
EAG14_RS15630	COG2258	MOSC domain
EAG14_RS15635	COG0588	phosphoglycerate mutase activity
EAG14_RS15640	COG1280	lysine exporter protein (LysE YggA)
EAG14_RS15665	COG0302	gtp cyclohydrolase
EAG14_RS15680	COG0745	RESPONSE REGULATOR receiver
EAG14_RS15695	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
EAG14_RS15715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EAG14_RS15730	COG2226	methyltransferase
EAG14_RS15755	COG3217	Mosc domain protein beta barrel domain protein
EAG14_RS15755	COG0633	Ferredoxin
EAG14_RS15760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_RS15775	COG1024	Enoyl-CoA hydratase
EAG14_RS15790	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS15795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EAG14_RS15810	COG0412	Dienelactone hydrolase
EAG14_RS15845	COG0625	glutathione transferase activity
EAG14_RS15865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_RS15920	COG5487	UPF0391 membrane protein
EAG14_RS15925	COG4585	Histidine kinase
EAG14_RS15945	COG0793	Belongs to the peptidase S41A family
EAG14_RS15950	COG0588	phosphoglycerate mutase activity
EAG14_RS15955	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EAG14_RS15970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
EAG14_RS15980	COG0583	DNA-binding transcription factor activity
EAG14_RS15985	COG0724	RNA recognition motif
EAG14_RS15995	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
EAG14_RS16005	COG0612	Peptidase, M16
EAG14_RS16010	COG0612	Peptidase, M16
EAG14_RS16030	COG5001	Diguanylate cyclase
EAG14_RS16060	COG2207	Transcriptional regulator
EAG14_RS16065	COG2807	transmembrane transport
EAG14_RS16075	COG1309	transcriptional regulator
EAG14_RS16110	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EAG14_RS16115	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS16120	COG1999	signal sequence binding
EAG14_RS16125	COG0109	protoheme IX farnesyltransferase activity
EAG14_RS16160	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
EAG14_RS16180	COG2226	methyltransferase
EAG14_RS16185	COG1040	competence protein
EAG14_RS16215	COG1132	(ABC) transporter
EAG14_RS16220	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EAG14_RS16225	COG0583	DNA-binding transcription factor activity
EAG14_RS16245	COG1280	lysine exporter protein (LysE YggA)
EAG14_RS16315	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
EAG14_RS16320	COG2205	protein histidine kinase activity
EAG14_RS16330	COG2204	response regulator
EAG14_RS16340	COG2943	transferase activity, transferring hexosyl groups
EAG14_RS16360	COG1763	Mo-molybdopterin cofactor biosynthetic process
EAG14_RS16385	COG0436	Aminotransferase
EAG14_RS16395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EAG14_RS16400	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
EAG14_RS16410	COG0305	Participates in initiation and elongation during chromosome replication
EAG14_RS16415	COG0359	binds to the 23S rRNA
EAG14_RS16420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EAG14_RS16430	COG0360	Binds together with S18 to 16S ribosomal RNA
EAG14_RS16435	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
EAG14_RS16440	COG0443	Heat shock 70 kDa protein
EAG14_RS16445	COG0484	heat shock protein binding
EAG14_RS16450	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
EAG14_RS16460	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
EAG14_RS16470	COG0066	3-isopropylmalate dehydratase activity
EAG14_RS16475	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_RS16480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EAG14_RS16490	COG0101	tRNA pseudouridine synthase activity
EAG14_RS16495	COG0135	phosphoribosylanthranilate isomerase activity
EAG14_RS16505	COG0159	tryptophan synthase activity
EAG14_RS16510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
EAG14_RS16515	COG0762	integral membrane protein
EAG14_RS16545	COG1215	transferase activity, transferring glycosyl groups
EAG14_RS16560	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EAG14_RS16565	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EAG14_RS16570	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
EAG14_RS16580	COG1472	Belongs to the glycosyl hydrolase 3 family
EAG14_RS16585	COG0736	holo-[acyl-carrier-protein] synthase activity
EAG14_RS16590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EAG14_RS16595	COG1381	Involved in DNA repair and RecF pathway recombination
EAG14_RS16600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EAG14_RS16605	COG0571	ribonuclease III activity
EAG14_RS16615	COG0681	Belongs to the peptidase S26 family
EAG14_RS16620	COG0481	GTPase activity
EAG14_RS16625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_RS16650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_RS16655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EAG14_RS16660	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS16670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EAG14_RS16675	COG0416	fatty acid biosynthetic process
EAG14_RS16680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EAG14_RS16685	COG1399	metal-binding, possibly nucleic acid-binding protein
EAG14_RS16690	COG0424	maF-like protein
EAG14_RS16695	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAG14_RS16700	COG0616	signal peptide processing
EAG14_RS16700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EAG14_RS16725	COG3022	response to hydroperoxide
EAG14_RS16735	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EAG14_RS16735	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
EAG14_RS16740	COG0840	transmembrane signaling receptor activity
EAG14_RS16745	COG0840	transmembrane signaling receptor activity
EAG14_RS16750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EAG14_RS16755	COG0697	spore germination
EAG14_RS16760	COG0583	DNA-binding transcription factor activity
EAG14_RS16780	COG0436	Aminotransferase
EAG14_RS16795	COG1012	belongs to the aldehyde dehydrogenase family
EAG14_RS16800	COG0583	DNA-binding transcription factor activity
EAG14_RS16805	COG5001	Diguanylate cyclase
EAG14_RS16805	COG4251	negative regulation of phosphorylation
EAG14_RS16805	COG3706	GGDEF domain
EAG14_RS16805	COG2203	Gaf domain
EAG14_RS16825	COG1414	Transcriptional regulator
EAG14_RS16830	COG3842	ATPase activity
EAG14_RS16835	COG1176	ABC-type spermidine putrescine transport system, permease component I
EAG14_RS16840	COG1177	transmembrane transport
EAG14_RS16855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_RS16890	COG0840	transmembrane signaling receptor activity
EAG14_RS16900	COG1595	DNA-templated transcription, initiation
EAG14_RS16910	COG1304	FMN binding
EAG14_RS16920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EAG14_RS16945	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS16950	COG0165	Argininosuccinate lyase
EAG14_RS16955	COG3275	phosphorelay sensor kinase activity
EAG14_RS16985	COG1178	ABC-type Fe3 transport system permease component
EAG14_RS16990	COG3842	ATPase activity
EAG14_RS17000	COG0840	transmembrane signaling receptor activity
EAG14_RS17020	COG0540	Belongs to the ATCase OTCase family
EAG14_RS17025	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
EAG14_RS17030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EAG14_RS17035	COG1678	Uncharacterized ACR, COG1678
EAG14_RS17040	COG0415	Belongs to the DNA photolyase family
EAG14_RS17045	COG0784	Response regulator, receiver
EAG14_RS17045	COG2198	Histidine kinase
EAG14_RS17045	COG0643	Histidine kinase
EAG14_RS17060	COG0835	chemotaxis
EAG14_RS17075	COG1773	rubredoxin
EAG14_RS17085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
EAG14_RS17095	COG1414	Transcriptional regulator
EAG14_RS17100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EAG14_RS17105	COG4654	Cytochrome c, class I
EAG14_RS17110	COG0138	bifunctional purine biosynthesis protein purh
EAG14_RS17115	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EAG14_RS17120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EAG14_RS17140	COG0012	GTP binding
EAG14_RS17145	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_RS17150	COG1653	transport
EAG14_RS17155	COG1175	transmembrane transport
EAG14_RS17160	COG0395	ABC-type sugar transport system, permease component
EAG14_RS17165	COG3842	ATPase activity
EAG14_RS17175	COG0584	glycerophosphoryl diester phosphodiesterase
EAG14_RS17190	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
EAG14_RS17195	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
EAG14_RS17200	COG2890	protein-(glutamine-N5) methyltransferase activity
EAG14_RS17210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EAG14_RS17215	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EAG14_RS17220	COG1253	flavin adenine dinucleotide binding
EAG14_RS17230	COG0442	prolyl-tRNA aminoacylation
EAG14_RS17235	COG0494	nUDIX hydrolase
EAG14_RS17240	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
EAG14_RS17245	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
EAG14_RS17250	COG0211	Belongs to the bacterial ribosomal protein bL27 family
EAG14_RS17255	COG0261	This protein binds to 23S rRNA in the presence of protein L20
EAG14_RS17260	COG0142	geranyltranstransferase activity
EAG14_RS17275	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
EAG14_RS17280	COG0237	dephospho-CoA kinase activity
EAG14_RS17285	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
EAG14_RS17290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EAG14_RS17295	COG0494	nUDIX hydrolase
EAG14_RS17305	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EAG14_RS17310	COG0653	protein targeting
EAG14_RS17315	COG0739	heme binding
EAG14_RS17330	COG2969	positive regulation of protein catabolic process
EAG14_RS17335	COG0625	glutathione transferase activity
EAG14_RS17340	COG2857	Cytochrome c1
EAG14_RS17345	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
EAG14_RS17360	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EAG14_RS17365	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EAG14_RS17370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EAG14_RS17375	COG0805	protein transport
EAG14_RS17380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAG14_RS17385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EAG14_RS17390	COG0537	adenosine 5'-monophosphoramidase activity
EAG14_RS17405	COG0140	phosphoribosyl-ATP diphosphatase activity
EAG14_RS17410	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EAG14_RS17415	COG0107	imidazoleglycerol-phosphate synthase activity
EAG14_RS17420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EAG14_RS17485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
EAG14_RS17495	COG0131	Imidazoleglycerol-phosphate dehydratase
EAG14_RS17500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
EAG14_RS17515	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
EAG14_RS17520	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
EAG14_RS17525	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EAG14_RS17540	COG0218	Necessary for normal cell division and for the maintenance of normal septation
EAG14_RS17550	COG1560	Kdo2-lipid A biosynthetic process
EAG14_RS17560	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
EAG14_RS17590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
EAG14_RS17595	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EAG14_RS17595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EAG14_RS17600	COG1051	belongs to the nudix hydrolase family
EAG14_RS17600	COG1056	cytidyltransferase-related domain
EAG14_RS17605	COG0840	transmembrane signaling receptor activity
EAG14_RS17610	COG5001	Diguanylate cyclase
EAG14_RS17625	COG1953	Uracil, thiamine, allantoin
EAG14_RS17635	COG0493	'glutamate synthase
EAG14_RS17640	COG1309	transcriptional regulator
EAG14_RS17655	COG0730	response to heat
EAG14_RS17660	COG1218	3'(2'),5'-bisphosphate nucleotidase
EAG14_RS17675	COG0175	sulfate reduction
EAG14_RS17725	COG3958	Transketolase
EAG14_RS17730	COG3959	Transketolase, thiamine diphosphate binding domain
EAG14_RS17745	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EAG14_RS17750	COG3754	Rhamnan synthesis protein F
EAG14_RS17795	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
EAG14_RS17800	COG0459	protein refolding
EAG14_RS17810	COG1858	cytochrome C peroxidase
EAG14_RS17830	COG0642	Histidine kinase
EAG14_RS17835	COG0800	Aldolase
EAG14_RS17860	COG0166	Belongs to the GPI family
EAG14_RS17870	COG0346	lactoylglutathione lyase activity
EAG14_RS17875	COG0837	glucose binding
EAG14_RS17880	COG3842	ATPase activity
EAG14_RS17885	COG0395	ABC-type sugar transport system, permease component
EAG14_RS17915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EAG14_RS17930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EAG14_RS17935	COG1309	transcriptional regulator
EAG14_RS17950	COG0737	Belongs to the 5'-nucleotidase family
EAG14_RS17955	COG4608	Belongs to the ABC transporter superfamily
EAG14_RS17960	COG0444	Belongs to the ABC transporter superfamily
EAG14_RS17965	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS17970	COG0747	negative chemotaxis
EAG14_RS17975	COG1473	amidohydrolase
EAG14_RS17985	COG0747	negative chemotaxis
EAG14_RS18000	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
EAG14_RS18005	COG1765	OsmC-like protein
EAG14_RS18010	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_RS18015	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
EAG14_RS18085	COG0840	transmembrane signaling receptor activity
EAG14_RS18090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EAG14_RS18095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
EAG14_RS18105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EAG14_RS18115	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EAG14_RS18120	COG1181	Belongs to the D-alanine--D-alanine ligase family
EAG14_RS18125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EAG14_RS18130	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
EAG14_RS18135	COG0772	Belongs to the SEDS family
EAG14_RS18140	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
EAG14_RS18145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EAG14_RS18150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EAG14_RS18155	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EAG14_RS18165	COG3116	cell division
EAG14_RS18170	COG0275	rRNA processing
EAG14_RS18175	COG2001	Belongs to the MraZ family
EAG14_RS18180	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
EAG14_RS18185	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
EAG14_RS18200	COG0523	cobalamin synthesis protein
EAG14_RS18205	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
EAG14_RS18210	COG0835	chemotaxis
EAG14_RS18230	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EAG14_RS18240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
EAG14_RS18245	COG0625	glutathione transferase activity
EAG14_RS18250	COG0583	DNA-binding transcription factor activity
EAG14_RS18255	COG2814	Major facilitator Superfamily
EAG14_RS18265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS18295	COG4650	regulator
EAG14_RS18315	COG1690	Belongs to the RtcB family
EAG14_RS18320	COG3541	Predicted nucleotidyltransferase
EAG14_RS18325	COG0430	RNA-3'-phosphate cyclase activity
EAG14_RS18335	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
EAG14_RS18340	COG0840	transmembrane signaling receptor activity
EAG14_RS18365	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EAG14_RS18370	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS18375	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS18380	COG0183	Belongs to the thiolase family
EAG14_RS18385	COG1024	Enoyl-CoA hydratase
EAG14_RS18385	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS18395	COG0501	Belongs to the peptidase M48B family
EAG14_RS18405	COG0418	dihydroorotase activity
EAG14_RS18410	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS18430	COG1126	abc transporter atp-binding protein
EAG14_RS18435	COG0765	amino acid transport
EAG14_RS18440	COG0765	amino acid transport
EAG14_RS18445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS18455	COG0583	DNA-binding transcription factor activity
EAG14_RS18465	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
EAG14_RS18465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
EAG14_RS18470	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EAG14_RS18475	COG1620	l-lactate permease
EAG14_RS18480	COG2186	Transcriptional regulator
EAG14_RS18485	COG1304	FMN binding
EAG14_RS18490	COG0277	FAD linked oxidase domain protein
EAG14_RS18500	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EAG14_RS18505	COG5265	(ABC) transporter
EAG14_RS18510	COG1607	acyl-coa hydrolase
EAG14_RS18525	COG1024	Enoyl-CoA hydratase
EAG14_RS18540	COG0183	Belongs to the thiolase family
EAG14_RS18550	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS18550	COG1024	Enoyl-CoA hydratase
EAG14_RS18560	COG1960	acyl-CoA dehydrogenase activity
EAG14_RS18570	COG1309	transcriptional regulator
EAG14_RS18575	COG0642	Histidine kinase
EAG14_RS18580	COG0745	RESPONSE REGULATOR receiver
EAG14_RS18585	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
EAG14_RS18600	COG2010	Cytochrome c
EAG14_RS18610	COG0714	Associated with various cellular activities
EAG14_RS18660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_RS18700	COG2165	general secretion pathway protein
EAG14_RS18710	COG2165	general secretion pathway protein
EAG14_RS18715	COG1459	type II secretion system
EAG14_RS18720	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EAG14_RS18765	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
EAG14_RS18770	COG1652	LysM domain
EAG14_RS18790	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EAG14_RS18795	COG0751	glycine-tRNA ligase activity
EAG14_RS18800	COG2329	Antibiotic biosynthesis monooxygenase
EAG14_RS18805	COG0752	glycyl-tRNA synthetase alpha subunit
EAG14_RS18815	COG0583	DNA-binding transcription factor activity
EAG14_RS18835	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EAG14_RS18860	COG1131	(ABC) transporter
EAG14_RS18880	COG3186	Phenylalanine-4-hydroxylase
EAG14_RS18890	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS18900	COG1129	ABC transporter
EAG14_RS18905	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS18915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EAG14_RS18920	COG1869	D-ribose catabolic process
EAG14_RS18935	COG0739	heme binding
EAG14_RS18935	COG0741	lytic transglycosylase activity
EAG14_RS18935	COG1196	nuclear chromosome segregation
EAG14_RS18940	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EAG14_RS18960	COG0617	tRNA 3'-terminal CCA addition
EAG14_RS18970	COG4944	Protein of unknown function (DUF1109)
EAG14_RS18975	COG1595	DNA-templated transcription, initiation
EAG14_RS18985	COG3220	belongs to the UPF0276 family
EAG14_RS19015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EAG14_RS19035	COG2175	clavaminate synthase activity
EAG14_RS19065	COG0037	tRNA processing
EAG14_RS19080	COG3616	Alanine racemase, N-terminal domain
EAG14_RS19095	COG0632	four-way junction helicase activity
EAG14_RS19100	COG1702	phosphate starvation-inducible protein PhoH
EAG14_RS19105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
EAG14_RS19110	COG0477	Major facilitator Superfamily
EAG14_RS19120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EAG14_RS19125	COG1845	cytochrome c oxidase, subunit III
EAG14_RS19130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EAG14_RS19145	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
EAG14_RS19150	COG0730	response to heat
EAG14_RS19155	COG1490	D-aminoacyl-tRNA deacylase activity
EAG14_RS19175	COG0840	transmembrane signaling receptor activity
EAG14_RS19185	COG0513	Belongs to the DEAD box helicase family
EAG14_RS19195	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EAG14_RS19200	COG3706	GGDEF domain
EAG14_RS19205	COG1131	(ABC) transporter
EAG14_RS19210	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
EAG14_RS19215	COG0842	Transport permease protein
EAG14_RS19230	COG1250	3-hydroxyacyl-CoA dehydrogenase
EAG14_RS19235	COG0642	Histidine kinase
EAG14_RS19255	COG1846	Transcriptional regulator
EAG14_RS19260	COG1764	response to oxidative stress
EAG14_RS19270	COG2815	serine threonine protein kinase
EAG14_RS19270	COG0515	serine threonine protein kinase
EAG14_RS19280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EAG14_RS19300	COG2205	protein histidine kinase activity
EAG14_RS19300	COG3850	Histidine kinase
EAG14_RS19300	COG4999	Histidine kinase
EAG14_RS19300	COG3437	response regulator, receiver
EAG14_RS19320	COG0326	Molecular chaperone. Has ATPase activity
EAG14_RS19330	COG1187	pseudouridine synthase activity
EAG14_RS19355	COG0840	transmembrane signaling receptor activity
EAG14_RS19360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_RS19370	COG3409	Peptidoglycan-binding domain 1 protein
EAG14_RS19370	COG3267	Type II secretory pathway component ExeA
EAG14_RS19390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EAG14_RS19425	COG0697	spore germination
EAG14_RS19445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EAG14_RS19480	COG0473	3-isopropylmalate dehydrogenase activity
EAG14_RS19505	COG2818	Glycosylase
EAG14_RS19520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_RS19545	COG1473	amidohydrolase
EAG14_RS19570	COG0596	Alpha beta hydrolase
EAG14_RS19615	COG3945	hemerythrin HHE cation binding domain
EAG14_RS19635	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EAG14_RS19640	COG0288	reversible hydration of carbon dioxide
EAG14_RS19650	COG2181	nitrate reductase activity
EAG14_RS19655	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
EAG14_RS19660	COG1140	nitrate reductase beta subunit
EAG14_RS19670	COG2223	nitrite transmembrane transporter activity
EAG14_RS19680	COG2197	response regulator
EAG14_RS19685	COG4585	Histidine kinase
EAG14_RS19700	COG0583	DNA-binding transcription factor activity
EAG14_RS19715	COG0277	FAD linked oxidase domain protein
EAG14_RS19725	COG1346	cytolysis
EAG14_RS19730	COG2733	membrane
EAG14_RS19745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EAG14_RS19755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_RS19765	COG2084	Dehydrogenase
EAG14_RS19770	COG2823	Periplasmic or secreted lipoprotein
EAG14_RS19775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
EAG14_RS19780	COG0792	nuclease activity
EAG14_RS19785	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EAG14_RS19790	COG0443	Heat shock 70 kDa protein
EAG14_RS19855	COG0582	viral genome integration into host DNA
EAG14_RS19865	COG2204	response regulator
EAG14_RS19880	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
EAG14_RS19880	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
EAG14_RS19890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
EAG14_RS19895	COG0085	RNA polymerase activity
EAG14_RS19900	COG0222	ribosome binding
EAG14_RS19905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
EAG14_RS19910	COG0081	regulation of translation
EAG14_RS19915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
EAG14_RS19925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EAG14_RS19935	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAG14_RS19965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS20000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
EAG14_RS20005	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
EAG14_RS20010	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
EAG14_RS20015	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
EAG14_RS20020	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
EAG14_RS20025	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
EAG14_RS20035	COG0356	it plays a direct role in the translocation of protons across the membrane
EAG14_RS20045	COG2921	Belongs to the UPF0250 family
EAG14_RS20050	COG0321	lipoyl(octanoyl) transferase activity
EAG14_RS20055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EAG14_RS20060	COG0662	Cupin 2, conserved barrel domain protein
EAG14_RS20060	COG2207	Transcriptional regulator
EAG14_RS20075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EAG14_RS20080	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EAG14_RS20100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EAG14_RS20115	COG0456	acetyltransferase
EAG14_RS20120	COG0678	peroxiredoxin activity
EAG14_RS20125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EAG14_RS20130	COG0255	Belongs to the universal ribosomal protein uL29 family
EAG14_RS20135	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EAG14_RS20140	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EAG14_RS20145	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
EAG14_RS20150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EAG14_RS20155	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
EAG14_RS20160	COG0089	rRNA binding
EAG14_RS20165	COG0088	Forms part of the polypeptide exit tunnel
EAG14_RS20170	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
EAG14_RS20175	COG0051	transcription antitermination factor activity, RNA binding
EAG14_RS20180	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
EAG14_RS20185	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
EAG14_RS20190	COG0049	tRNA binding
EAG14_RS20195	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EAG14_RS20200	COG1686	Belongs to the peptidase S11 family
EAG14_RS20205	COG2945	thiolester hydrolase activity
EAG14_RS20220	COG1981	membrane
EAG14_RS20230	COG0598	Magnesium transport protein CorA
EAG14_RS20235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EAG14_RS20235	COG0519	Catalyzes the synthesis of GMP from XMP
EAG14_RS20240	COG0840	transmembrane signaling receptor activity
EAG14_RS20255	COG0412	Dienelactone hydrolase
EAG14_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
EAG14_RS20265	COG2095	MarC family integral membrane protein
EAG14_RS20270	COG0745	RESPONSE REGULATOR receiver
EAG14_RS20275	COG2205	protein histidine kinase activity
EAG14_RS20280	COG4452	Inner membrane protein CreD
EAG14_RS20300	COG3237	CsbD-like
EAG14_RS20330	COG0583	DNA-binding transcription factor activity
EAG14_RS20355	COG1127	ABC transporter
EAG14_RS20360	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EAG14_RS20385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS20390	COG0765	amino acid transport
EAG14_RS20415	COG0768	penicillin binding
EAG14_RS20430	COG1077	Cell shape determining protein MreB Mrl
EAG14_RS20435	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAG14_RS20440	COG0154	amidase activity
EAG14_RS20445	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EAG14_RS20455	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
EAG14_RS20460	COG0708	Exodeoxyribonuclease III
EAG14_RS20465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EAG14_RS20470	COG4774	siderophore transport
EAG14_RS20480	COG0471	metal ion transport
EAG14_RS20485	COG0039	L-malate dehydrogenase activity
EAG14_RS20520	COG2211	Major facilitator Superfamily
EAG14_RS20525	COG0745	RESPONSE REGULATOR receiver
EAG14_RS20535	COG0477	Major facilitator Superfamily
EAG14_RS20550	COG4641	Protein conserved in bacteria
EAG14_RS20550	COG0438	transferase activity, transferring glycosyl groups
EAG14_RS20600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EAG14_RS20605	COG0625	glutathione transferase activity
EAG14_RS20610	COG0747	negative chemotaxis
EAG14_RS20660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EAG14_RS20665	COG0477	Major facilitator Superfamily
EAG14_RS20675	COG0386	Belongs to the glutathione peroxidase family
EAG14_RS20695	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
EAG14_RS20700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EAG14_RS20705	COG0247	lactate metabolic process
EAG14_RS20715	COG0277	FAD linked oxidase domain protein
EAG14_RS20720	COG0004	ammonium transporteR
EAG14_RS20725	COG0347	Belongs to the P(II) protein family
EAG14_RS20745	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EAG14_RS20785	COG0583	DNA-binding transcription factor activity
EAG14_RS20805	COG1024	Enoyl-CoA hydratase
EAG14_RS20845	COG0348	domain, Protein
EAG14_RS20890	COG0683	leucine binding
EAG14_RS20910	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
EAG14_RS20955	COG0251	oxidation-reduction process
EAG14_RS20975	COG0646	methionine synthase
EAG14_RS20975	COG1410	methionine synthase
EAG14_RS21020	COG2198	Histidine kinase
EAG14_RS21020	COG0784	Response regulator, receiver
EAG14_RS21020	COG5002	protein histidine kinase activity
EAG14_RS21045	COG2326	polyphosphate kinase activity
EAG14_RS21065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EAG14_RS21100	COG0826	peptidase U32
EAG14_RS21105	COG0037	tRNA processing
EAG14_RS21155	COG1309	transcriptional regulator
EAG14_RS21165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EAG14_RS21170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EAG14_RS21175	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
EAG14_RS21210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EAG14_RS21230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_RS21245	COG1289	transmembrane transporter activity
EAG14_RS21250	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EAG14_RS21260	COG0850	regulation of cytokinetic process
EAG14_RS21275	COG1183	phosphatidylcholine synthase activity
EAG14_RS21280	COG0318	PFAM AMP-dependent synthetase and ligase
EAG14_RS21290	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EAG14_RS21305	COG0501	Belongs to the peptidase M48B family
EAG14_RS21330	COG2233	PERMEase
EAG14_RS21340	COG0683	leucine binding
EAG14_RS21350	COG2050	protein possibly involved in aromatic compounds catabolism
EAG14_RS21380	COG2096	Adenosyltransferase
EAG14_RS21395	COG1126	abc transporter atp-binding protein
EAG14_RS21400	COG0765	amino acid transport
EAG14_RS21425	COG0277	FAD linked oxidase domain protein
EAG14_RS21460	COG0640	Transcriptional regulator
EAG14_RS21470	COG0747	negative chemotaxis
EAG14_RS21515	COG2203	Gaf domain
EAG14_RS21515	COG3706	GGDEF domain
EAG14_RS21515	COG4251	negative regulation of phosphorylation
EAG14_RS21515	COG5001	Diguanylate cyclase
EAG14_RS21525	COG1136	(ABC) transporter
EAG14_RS21525	COG0577	efflux transmembrane transporter activity
EAG14_RS21530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EAG14_RS21565	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EAG14_RS21570	COG1522	sequence-specific DNA binding
EAG14_RS21585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EAG14_RS21600	COG2040	homocysteine
EAG14_RS21650	COG4794	Type iii secretion
EAG14_RS21655	COG4790	Type iii secretion
EAG14_RS21715	COG4789	Type iii secretion
EAG14_RS21720	COG0739	heme binding
EAG14_RS21720	COG1196	nuclear chromosome segregation
EAG14_RS21720	COG0741	lytic transglycosylase activity
EAG14_RS21725	COG4792	protein secretion
EAG14_RS21745	COG3411	Ferredoxin
EAG14_RS21780	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
EAG14_RS21840	COG1475	DNA binding
EAG14_RS21860	COG1192	Involved in chromosome partitioning
EAG14_RS21870	COG0357	Ribosomal RNA small subunit methyltransferase G
EAG14_RS21875	COG0445	tRNA wobble uridine modification
EAG14_RS21890	COG0840	transmembrane signaling receptor activity
EAG14_RS21895	COG1595	DNA-templated transcription, initiation
EAG14_RS21900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EAG14_RS21915	COG1902	pentaerythritol trinitrate reductase activity
EAG14_RS21930	COG2217	Heavy metal translocating P-type atpase
EAG14_RS21940	COG0789	Transcriptional regulator
EAG14_RS21950	COG2974	May be involved in recombination
EAG14_RS21965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EAG14_RS21970	COG0791	NLP P60 protein
EAG14_RS21975	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EAG14_RS21985	COG2176	DNA-directed DNA polymerase activity
EAG14_RS21995	COG2234	aminopeptidase activity
EAG14_RS22000	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
EAG14_RS22005	COG2824	Alkylphosphonate utilization operon protein PhnA
EAG14_RS22010	COG1199	ATP-dependent helicase activity
EAG14_RS22025	COG2203	Gaf domain
EAG14_RS22025	COG2199	diguanylate cyclase activity
EAG14_RS22030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EAG14_RS22120	COG1475	DNA binding
EAG14_RS22160	COG0732	type I restriction modification DNA specificity domain
EAG14_RS22190	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
EAG14_RS22195	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EAG14_RS22200	COG0594	ribonuclease P activity
EAG14_RS22205	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
EAG14_RS22210	COG0706	membrane insertase activity
EAG14_RS22215	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
EAG14_RS22255	COG0747	negative chemotaxis
EAG14_RS22265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EAG14_RS22270	COG4608	Belongs to the ABC transporter superfamily
EAG14_RS22275	COG0444	Belongs to the ABC transporter superfamily
EAG14_RS22280	COG0154	amidase activity
EAG14_RS22290	COG0281	malic enzyme
EAG14_RS22290	COG0280	phosphate acetyltransferase
EAG14_RS22305	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EAG14_RS22310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EAG14_RS22315	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EAG14_RS22325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EAG14_RS22365	COG3181	Tripartite tricarboxylate transporter family receptor
EAG14_RS22375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EAG14_RS22380	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
EAG14_RS22395	COG2197	response regulator
EAG14_RS22425	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
EAG14_RS22430	COG2137	regulation of response to DNA damage stimulus
EAG14_RS22435	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
EAG14_RS22440	COG0045	succinate-CoA ligase (ADP-forming) activity
EAG14_RS22445	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EAG14_RS22455	COG0631	protein serine/threonine phosphatase activity
EAG14_RS22460	COG1716	ATPase activity
EAG14_RS22475	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_RS22480	COG4969	Belongs to the N-Me-Phe pilin family
EAG14_RS22495	COG0315	cyclic pyranopterin monophosphate synthase activity
EAG14_RS22500	COG4783	chaperone-mediated protein folding
EAG14_RS22505	COG1950	PFAM Membrane protein of
EAG14_RS22520	COG0861	Integral membrane protein TerC family