locus-tag	class	description
M9799_RS00020	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
M9799_RS00025	COG0778	Nitroreductase
M9799_RS00030	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
M9799_RS00040	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS00070	COG3237	CsbD-like
M9799_RS00095	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS00115	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M9799_RS00130	COG4654	Cytochrome c, class I
M9799_RS00140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M9799_RS00155	COG4176	ABC-type proline glycine betaine transport system permease component
M9799_RS00160	COG2113	Glycine betaine
M9799_RS00180	COG0114	fumarate hydratase activity
M9799_RS00190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M9799_RS00215	COG1451	nucleotide metabolic process
M9799_RS00230	COG1742	UPF0060 membrane protein
M9799_RS00240	COG4181	ATPase activity
M9799_RS00255	COG0626	cystathionine gamma-synthase activity
M9799_RS00265	COG0659	secondary active sulfate transmembrane transporter activity
M9799_RS00280	COG1054	Belongs to the UPF0176 family
M9799_RS00295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M9799_RS00300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M9799_RS00305	COG1902	pentaerythritol trinitrate reductase activity
M9799_RS00320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M9799_RS00325	COG0477	Major facilitator Superfamily
M9799_RS00335	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M9799_RS00340	COG1845	cytochrome c oxidase, subunit III
M9799_RS00345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M9799_RS00360	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
M9799_RS00365	COG0109	protoheme IX farnesyltransferase activity
M9799_RS00370	COG1612	heme a metabolic process
M9799_RS00390	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M9799_RS00400	COG0795	lipopolysaccharide-transporting ATPase activity
M9799_RS00410	COG0583	DNA-binding transcription factor activity
M9799_RS00415	COG0436	Aminotransferase
M9799_RS00440	COG0424	maF-like protein
M9799_RS00445	COG1115	amino acid carrier protein
M9799_RS00450	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
M9799_RS00455	COG0799	negative regulation of ribosome biogenesis
M9799_RS00460	COG0408	coproporphyrinogen oxidase activity
M9799_RS00465	COG0151	Belongs to the GarS family
M9799_RS00470	COG0217	transcriptional regulatory protein
M9799_RS00480	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
M9799_RS00485	COG0217	transcriptional regulatory protein
M9799_RS00490	COG1301	dicarboxylic acid transport
M9799_RS00495	COG2133	pyrroloquinoline quinone binding
M9799_RS00500	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M9799_RS00510	COG0700	Nucleoside recognition
M9799_RS00515	COG2925	Exonuclease
M9799_RS00525	COG0542	response to heat
M9799_RS00530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M9799_RS00545	COG1199	ATP-dependent helicase activity
M9799_RS00550	COG3706	GGDEF domain
M9799_RS00565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS00590	COG0564	pseudouridine synthase activity
M9799_RS00595	COG2982	Protein involved in outer membrane biogenesis
M9799_RS00600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M9799_RS00615	COG4566	intracellular signal transduction
M9799_RS00620	COG0753	catalase activity
M9799_RS00640	COG4120	Belongs to the binding-protein-dependent transport system permease family
M9799_RS00650	COG0833	amino acid
M9799_RS00665	COG0404	The glycine cleavage system catalyzes the degradation of glycine
M9799_RS00670	COG0509	glycine decarboxylation via glycine cleavage system
M9799_RS00675	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M9799_RS00675	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
M9799_RS00685	COG0564	pseudouridine synthase activity
M9799_RS00695	COG0559	Belongs to the binding-protein-dependent transport system permease family
M9799_RS00715	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS00725	COG0583	DNA-binding transcription factor activity
M9799_RS00730	COG2814	Major facilitator Superfamily
M9799_RS00735	COG0583	DNA-binding transcription factor activity
M9799_RS00740	COG1741	Belongs to the pirin family
M9799_RS00745	COG1335	isochorismatase
M9799_RS00750	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M9799_RS00765	COG0583	DNA-binding transcription factor activity
M9799_RS00775	COG0589	response to stress
M9799_RS00785	COG4948	Mandelate Racemase Muconate Lactonizing
M9799_RS00815	COG2814	Major facilitator Superfamily
M9799_RS00820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M9799_RS00825	COG1414	Transcriptional regulator
M9799_RS00840	COG0667	Aldo Keto reductase
M9799_RS00870	COG2159	amidohydrolase
M9799_RS00880	COG2828	Protein conserved in bacteria
M9799_RS00890	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS00900	COG1643	Atp-dependent helicase
M9799_RS00905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M9799_RS00905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
M9799_RS00915	COG1187	pseudouridine synthase activity
M9799_RS00920	COG0583	DNA-binding transcription factor activity
M9799_RS00935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M9799_RS00940	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
M9799_RS00945	COG2860	membrane
M9799_RS00950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M9799_RS00950	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M9799_RS00970	COG0175	sulfate reduction
M9799_RS00980	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M9799_RS00985	COG0492	ferredoxin-NADP+ reductase activity
M9799_RS00995	COG0688	phosphatidylethanolamine metabolic process
M9799_RS01000	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
M9799_RS01045	COG0038	chloride channel
M9799_RS01095	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
M9799_RS01100	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M9799_RS01105	COG4208	sulfate ABC transporter
M9799_RS01115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M9799_RS01130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M9799_RS01140	COG4772	TonB-dependent receptor
M9799_RS01150	COG1464	Belongs to the NlpA lipoprotein family
M9799_RS01155	COG2011	ABC-type metal ion transport system permease component
M9799_RS01160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M9799_RS01165	COG1464	Belongs to the NlpA lipoprotein family
M9799_RS01180	COG0789	Transcriptional regulator
M9799_RS01185	COG0776	regulation of translation
M9799_RS01190	COG0072	phenylalanine-tRNA ligase activity
M9799_RS01190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9799_RS01195	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
M9799_RS01200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
M9799_RS01205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
M9799_RS01210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
M9799_RS01215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
M9799_RS01220	COG4770	biotin carboxylase activity
M9799_RS01225	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
M9799_RS01230	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
M9799_RS01235	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
M9799_RS01285	COG2885	chlorophyll binding
M9799_RS01295	COG2274	protein secretion by the type I secretion system
M9799_RS01300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS01325	COG4964	Belongs to the GSP D family
M9799_RS01430	COG0737	Belongs to the 5'-nucleotidase family
M9799_RS01435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M9799_RS01440	COG2010	Cytochrome c
M9799_RS01440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M9799_RS01460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M9799_RS01490	COG0322	excinuclease ABC activity
M9799_RS01500	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
M9799_RS01515	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M9799_RS01525	COG4774	siderophore transport
M9799_RS01530	COG3128	pkhd-type hydroxylase
M9799_RS01565	COG3193	protein, possibly involved in utilization of glycolate and propanediol
M9799_RS01580	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
M9799_RS01585	COG3191	aminopeptidase activity
M9799_RS01590	COG0488	(ABC) transporter
M9799_RS01595	COG0513	Belongs to the DEAD box helicase family
M9799_RS01605	COG1752	Esterase of the alpha-beta hydrolase superfamily
M9799_RS01615	COG0583	DNA-binding transcription factor activity
M9799_RS01625	COG2011	ABC-type metal ion transport system permease component
M9799_RS01630	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M9799_RS01645	COG1609	Transcriptional regulator
M9799_RS01655	COG4948	Mandelate Racemase Muconate Lactonizing
M9799_RS01665	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
M9799_RS01670	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M9799_RS01675	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS01680	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
M9799_RS01685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
M9799_RS01690	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS01700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M9799_RS01710	COG2205	protein histidine kinase activity
M9799_RS01740	COG1716	ATPase activity
M9799_RS01740	COG5001	Diguanylate cyclase
M9799_RS01755	COG4566	intracellular signal transduction
M9799_RS01760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS01795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M9799_RS01800	COG0596	Alpha beta hydrolase
M9799_RS01805	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS01825	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M9799_RS01825	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
M9799_RS01830	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
M9799_RS01830	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
M9799_RS01835	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M9799_RS01840	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS01845	COG0560	Phosphoserine phosphatase
M9799_RS01855	COG3530	Putative quorum-sensing-regulated virulence factor
M9799_RS01860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M9799_RS01865	COG1120	ATPase activity
M9799_RS01870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS01890	COG2186	Transcriptional regulator
M9799_RS01895	COG4948	Mandelate Racemase Muconate Lactonizing
M9799_RS01915	COG0583	DNA-binding transcription factor activity
M9799_RS01925	COG2900	Belongs to the SlyX family
M9799_RS01930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M9799_RS01935	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M9799_RS01940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS01950	COG1960	acyl-CoA dehydrogenase activity
M9799_RS01955	COG0583	DNA-binding transcription factor activity
M9799_RS01960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M9799_RS01975	COG1492	cobalamin metabolic process
M9799_RS01980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M9799_RS01985	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
M9799_RS01990	COG0778	Nitroreductase
M9799_RS01995	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
M9799_RS02000	COG1120	ATPase activity
M9799_RS02005	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS02035	COG3237	CsbD-like
M9799_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS02075	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
M9799_RS02090	COG4654	Cytochrome c, class I
M9799_RS02100	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M9799_RS02110	COG4175	Glycine betaine
M9799_RS02120	COG2113	Glycine betaine
M9799_RS02135	COG0114	fumarate hydratase activity
M9799_RS02145	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M9799_RS02175	COG1451	nucleotide metabolic process
M9799_RS02185	COG0812	UDP-N-acetylmuramate dehydrogenase activity
M9799_RS02190	COG1666	GTP binding
M9799_RS02195	COG3577	Aspartyl protease
M9799_RS02205	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
M9799_RS02210	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M9799_RS02215	COG0667	Aldo Keto reductase
M9799_RS02235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS02240	COG1538	Outer membrane efflux protein
M9799_RS02260	COG1619	proteins homologs of microcin C7 resistance protein MccF
M9799_RS02270	COG4771	TonB-dependent receptor
M9799_RS02285	COG3842	ATPase activity
M9799_RS02290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M9799_RS02295	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
M9799_RS02300	COG2239	Acts as a magnesium transporter
M9799_RS02325	COG2354	Protein conserved in bacteria
M9799_RS02335	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
M9799_RS02340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS02345	COG4558	Periplasmic binding protein
M9799_RS02350	COG3720	iron ion transport
M9799_RS02360	COG4771	TonB-dependent receptor
M9799_RS02365	COG2986	histidine ammonia-lyase
M9799_RS02370	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
M9799_RS02375	COG1228	amidohydrolase
M9799_RS02385	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M9799_RS02385	COG0047	phosphoribosylformylglycinamidine synthase activity
M9799_RS02400	COG0242	peptide deformylase activity
M9799_RS02425	COG2175	clavaminate synthase activity
M9799_RS02440	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M9799_RS02445	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
M9799_RS02450	COG1414	Transcriptional regulator
M9799_RS02465	COG1183	phosphatidylcholine synthase activity
M9799_RS02470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
M9799_RS02475	COG0440	acetolactate synthase activity
M9799_RS02480	COG0028	Belongs to the TPP enzyme family
M9799_RS02505	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M9799_RS02515	COG0347	Belongs to the P(II) protein family
M9799_RS02530	COG0840	transmembrane signaling receptor activity
M9799_RS02535	COG0835	chemotaxis
M9799_RS02540	COG0840	transmembrane signaling receptor activity
M9799_RS02545	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M9799_RS02550	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9799_RS02560	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M9799_RS02565	COG0746	molybdenum cofactor guanylyltransferase activity
M9799_RS02570	COG0303	'Molybdopterin
M9799_RS02580	COG0328	RNA-DNA hybrid ribonuclease activity
M9799_RS02585	COG2226	methyltransferase
M9799_RS02590	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M9799_RS02595	COG0741	lytic transglycosylase activity
M9799_RS02595	COG1388	LysM domain
M9799_RS02605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M9799_RS02610	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
M9799_RS02615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M9799_RS02625	COG0693	protein deglycase activity
M9799_RS02640	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
M9799_RS02650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
M9799_RS02655	COG0254	rRNA binding
M9799_RS02665	COG0534	Mate efflux family protein
M9799_RS02670	COG5002	protein histidine kinase activity
M9799_RS02675	COG0745	RESPONSE REGULATOR receiver
M9799_RS02685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M9799_RS02690	COG0581	inorganic phosphate transmembrane transporter activity
M9799_RS02695	COG0573	inorganic phosphate transmembrane transporter activity
M9799_RS02700	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M9799_RS02720	COG0248	Ppx GppA phosphatase
M9799_RS02730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M9799_RS02740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M9799_RS02745	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
M9799_RS02750	COG1534	Rna-binding protein
M9799_RS02765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M9799_RS02770	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
M9799_RS02775	COG0505	Belongs to the CarA family
M9799_RS02780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M9799_RS02785	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M9799_RS02790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M9799_RS02795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M9799_RS02800	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M9799_RS02805	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M9799_RS02815	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M9799_RS02820	COG0750	zinc metalloprotease
M9799_RS02825	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
M9799_RS02830	COG0575	Belongs to the CDS family
M9799_RS02840	COG0233	cytoplasmic translational termination
M9799_RS02845	COG0528	UMP kinase activity
M9799_RS02850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
M9799_RS02855	COG0052	Belongs to the universal ribosomal protein uS2 family
M9799_RS02865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M9799_RS02870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M9799_RS02870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M9799_RS02875	COG0557	exoribonuclease II activity
M9799_RS02900	COG0741	lytic transglycosylase activity
M9799_RS02905	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
M9799_RS02910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M9799_RS02915	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
M9799_RS02930	COG2267	carboxylic ester hydrolase activity
M9799_RS02935	COG1295	ribonuclease BN
M9799_RS02945	COG0277	FAD linked oxidase domain protein
M9799_RS02970	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M9799_RS02990	COG2165	general secretion pathway protein
M9799_RS02995	COG4796	Type ii and iii secretion system protein
M9799_RS03035	COG1024	Enoyl-CoA hydratase
M9799_RS03040	COG0604	alcohol dehydrogenase
M9799_RS03040	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS03040	COG3321	synthase
M9799_RS03045	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS03055	COG0028	Belongs to the TPP enzyme family
M9799_RS03065	COG1408	metallophosphoesterase
M9799_RS03075	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS03090	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M9799_RS03125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M9799_RS03130	COG0697	spore germination
M9799_RS03135	COG1960	acyl-CoA dehydrogenase activity
M9799_RS03140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M9799_RS03155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS03175	COG0431	NADPH-dependent FMN reductase
M9799_RS03180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M9799_RS03190	COG2200	EAL domain
M9799_RS03190	COG2202	Pas domain
M9799_RS03190	COG2199	diguanylate cyclase activity
M9799_RS03205	COG0745	RESPONSE REGULATOR receiver
M9799_RS03210	COG2205	protein histidine kinase activity
M9799_RS03225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M9799_RS03230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M9799_RS03250	COG1881	PFAM PEBP family protein
M9799_RS03255	COG0708	Exodeoxyribonuclease III
M9799_RS03270	COG3852	Histidine kinase
M9799_RS03280	COG0174	glutamine synthetase
M9799_RS03315	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M9799_RS03320	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
M9799_RS03325	COG0330	HflC and HflK could
M9799_RS03330	COG0330	HflC and HflK could
M9799_RS03335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M9799_RS03340	COG1923	regulation of RNA biosynthetic process
M9799_RS03345	COG1160	GTP binding
M9799_RS03350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M9799_RS03360	COG0124	histidyl-tRNA synthetase
M9799_RS03365	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
M9799_RS03380	COG0820	rRNA (adenine-C2-)-methyltransferase activity
M9799_RS03385	COG0105	UTP biosynthetic process
M9799_RS03390	COG1187	pseudouridine synthase activity
M9799_RS03395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M9799_RS03400	COG0564	pseudouridine synthase activity
M9799_RS03410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M9799_RS03415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M9799_RS03420	COG0604	alcohol dehydrogenase
M9799_RS03420	COG3321	synthase
M9799_RS03420	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS03425	COG0786	glutamate:sodium symporter activity
M9799_RS03435	COG0024	Methionine aminopeptidase
M9799_RS03450	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M9799_RS03480	COG0402	S-adenosylhomocysteine deaminase activity
M9799_RS03505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS03520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS03530	COG0583	DNA-binding transcription factor activity
M9799_RS03550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
M9799_RS03555	COG3634	alkyl hydroperoxide reductase activity
M9799_RS03570	COG4628	conserved protein (DUF2132)
M9799_RS03580	COG2308	Evidence 4 Homologs of previously reported genes of
M9799_RS03600	COG0739	heme binding
M9799_RS03600	COG0741	lytic transglycosylase activity
M9799_RS03600	COG1196	nuclear chromosome segregation
M9799_RS03625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M9799_RS03630	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
M9799_RS03640	COG2850	peptidyl-arginine hydroxylation
M9799_RS03650	COG1012	belongs to the aldehyde dehydrogenase family
M9799_RS03655	COG1609	Transcriptional regulator
M9799_RS03660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M9799_RS03685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M9799_RS03690	COG0504	CTP synthase activity
M9799_RS03695	COG2877	3-deoxy-8-phosphooctulonate synthase activity
M9799_RS03705	COG0148	phosphopyruvate hydratase activity
M9799_RS03710	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M9799_RS03720	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M9799_RS03730	COG2833	Protein of unknown function (DUF455)
M9799_RS03740	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
M9799_RS03750	COG4974	Belongs to the 'phage' integrase family
M9799_RS03760	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M9799_RS03765	COG0802	atpase or kinase
M9799_RS03770	COG0860	N-Acetylmuramoyl-L-alanine amidase
M9799_RS03780	COG0586	Pfam SNARE associated Golgi protein
M9799_RS03790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M9799_RS03795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M9799_RS03805	COG2267	carboxylic ester hydrolase activity
M9799_RS03810	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
M9799_RS03815	COG1136	(ABC) transporter
M9799_RS03820	COG0071	Belongs to the small heat shock protein (HSP20) family
M9799_RS03875	COG1007	ATP synthesis coupled electron transport
M9799_RS03890	COG0713	ATP synthesis coupled electron transport
M9799_RS03900	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M9799_RS03905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
M9799_RS03910	COG1034	ATP synthesis coupled electron transport
M9799_RS03925	COG0649	NAD binding
M9799_RS03930	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M9799_RS03935	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M9799_RS03940	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M9799_RS03955	COG0149	triose-phosphate isomerase activity
M9799_RS03960	COG0604	alcohol dehydrogenase
M9799_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS03960	COG3321	synthase
M9799_RS03965	COG1185	polyribonucleotide nucleotidyltransferase activity
M9799_RS03970	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
M9799_RS04010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M9799_RS04010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M9799_RS04020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M9799_RS04035	COG2264	protein methyltransferase activity
M9799_RS04055	COG0542	response to heat
M9799_RS04060	COG0314	molybdopterin synthase activity
M9799_RS04085	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
M9799_RS04090	COG0303	'Molybdopterin
M9799_RS04095	COG1763	Mo-molybdopterin cofactor biosynthetic process
M9799_RS04110	COG0436	Aminotransferase
M9799_RS04120	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M9799_RS04125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
M9799_RS04135	COG0305	Participates in initiation and elongation during chromosome replication
M9799_RS04140	COG0359	binds to the 23S rRNA
M9799_RS04145	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
M9799_RS04150	COG2965	DNA replication, synthesis of RNA primer
M9799_RS04155	COG0360	Binds together with S18 to 16S ribosomal RNA
M9799_RS04160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
M9799_RS04165	COG0443	Heat shock 70 kDa protein
M9799_RS04170	COG0484	heat shock protein binding
M9799_RS04180	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M9799_RS04185	COG0066	3-isopropylmalate dehydratase activity
M9799_RS04190	COG0473	3-isopropylmalate dehydrogenase activity
M9799_RS04215	COG0101	tRNA pseudouridine synthase activity
M9799_RS04220	COG0135	phosphoribosylanthranilate isomerase activity
M9799_RS04225	COG0133	tryptophan synthase activity
M9799_RS04230	COG0159	tryptophan synthase activity
M9799_RS04235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
M9799_RS04240	COG0762	integral membrane protein
M9799_RS04245	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M9799_RS04250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
M9799_RS04255	COG0745	RESPONSE REGULATOR receiver
M9799_RS04275	COG1472	Belongs to the glycosyl hydrolase 3 family
M9799_RS04280	COG0736	holo-[acyl-carrier-protein] synthase activity
M9799_RS04285	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M9799_RS04290	COG1381	Involved in DNA repair and RecF pathway recombination
M9799_RS04295	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M9799_RS04300	COG0571	ribonuclease III activity
M9799_RS04310	COG0681	Belongs to the peptidase S26 family
M9799_RS04315	COG0481	GTPase activity
M9799_RS04320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M9799_RS04325	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
M9799_RS04340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M9799_RS04345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M9799_RS04350	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS04355	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M9799_RS04360	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
M9799_RS04365	COG0416	fatty acid biosynthetic process
M9799_RS04370	COG0333	Belongs to the bacterial ribosomal protein bL32 family
M9799_RS04375	COG1399	metal-binding, possibly nucleic acid-binding protein
M9799_RS04380	COG0424	maF-like protein
M9799_RS04385	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
M9799_RS04390	COG0616	signal peptide processing
M9799_RS04390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M9799_RS04400	COG0564	pseudouridine synthase activity
M9799_RS04405	COG1530	ribonuclease E activity
M9799_RS04410	COG3022	response to hydroperoxide
M9799_RS04420	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
M9799_RS04420	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
M9799_RS04425	COG0840	transmembrane signaling receptor activity
M9799_RS04430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M9799_RS04440	COG1304	FMN binding
M9799_RS04445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M9799_RS04455	COG0395	ABC-type sugar transport system, permease component
M9799_RS04470	COG3842	ATPase activity
M9799_RS04485	COG0165	Argininosuccinate lyase
M9799_RS04490	COG3275	phosphorelay sensor kinase activity
M9799_RS04515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M9799_RS04535	COG0210	DNA helicase
M9799_RS04540	COG0516	GMP reductase activity
M9799_RS04545	COG2084	Dehydrogenase
M9799_RS04570	COG2814	Major facilitator Superfamily
M9799_RS04575	COG0513	Belongs to the DEAD box helicase family
M9799_RS04580	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M9799_RS04585	COG0501	Belongs to the peptidase M48B family
M9799_RS04590	COG2154	pterin-4-alpha-carbinolamine dehydratase
M9799_RS04595	COG1162	GTPase activity
M9799_RS04605	COG2274	protein secretion by the type I secretion system
M9799_RS04630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
M9799_RS04640	COG0335	large ribosomal subunit rRNA binding
M9799_RS04645	COG0336	Belongs to the RNA methyltransferase TrmD family
M9799_RS04650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M9799_RS04655	COG0228	four-way junction DNA binding
M9799_RS04670	COG0306	phosphate transporter
M9799_RS04675	COG1392	Phosphate transport regulator
M9799_RS04680	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M9799_RS04685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M9799_RS04690	COG1674	ftsk spoiiie
M9799_RS04695	COG0492	ferredoxin-NADP+ reductase activity
M9799_RS04700	COG0227	Belongs to the bacterial ribosomal protein bL28 family
M9799_RS04705	COG0267	Belongs to the bacterial ribosomal protein bL33 family
M9799_RS04710	COG1404	Belongs to the peptidase S8 family
M9799_RS04720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M9799_RS04720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M9799_RS04730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M9799_RS04735	COG3132	Protein of unknown function, DUF480
M9799_RS04740	COG1960	acyl-CoA dehydrogenase activity
M9799_RS04750	COG3781	membrane
M9799_RS04770	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M9799_RS04785	COG0196	riboflavin kinase activity
M9799_RS04790	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M9799_RS04795	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
M9799_RS04800	COG1283	sodium-dependent phosphate transmembrane transporter activity
M9799_RS04815	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS04830	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M9799_RS04845	COG0084	hydrolase, TatD family'
M9799_RS04850	COG1136	(ABC) transporter
M9799_RS04855	COG4591	ABC-type transport system involved in lipoprotein release permease component
M9799_RS04870	COG0613	PHP domain protein
M9799_RS04875	COG0009	L-threonylcarbamoyladenylate synthase
M9799_RS04885	COG1994	Peptidase M50
M9799_RS04890	COG0180	Tryptophanyl-tRNA synthetase
M9799_RS04930	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
M9799_RS04940	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M9799_RS04950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS04960	COG1420	regulation of RNA biosynthetic process
M9799_RS04965	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M9799_RS04970	COG0497	DNA recombination
M9799_RS04975	COG1660	Displays ATPase and GTPase activities
M9799_RS04980	COG1194	a g-specific adenine glycosylase
M9799_RS04985	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
M9799_RS04995	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M9799_RS05000	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
M9799_RS05010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M9799_RS05015	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
M9799_RS05020	COG0193	aminoacyl-tRNA hydrolase activity
M9799_RS05025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M9799_RS05035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M9799_RS05045	COG4608	Belongs to the ABC transporter superfamily
M9799_RS05050	COG0747	negative chemotaxis
M9799_RS05055	COG1280	lysine exporter protein (LysE YggA)
M9799_RS05065	COG0302	gtp cyclohydrolase
M9799_RS05080	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
M9799_RS05100	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M9799_RS05115	COG2226	methyltransferase
M9799_RS05135	COG1653	transport
M9799_RS05140	COG1175	transmembrane transport
M9799_RS05145	COG0395	ABC-type sugar transport system, permease component
M9799_RS05150	COG3842	ATPase activity
M9799_RS05155	COG0584	glycerophosphoryl diester phosphodiesterase
M9799_RS05170	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
M9799_RS05175	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
M9799_RS05180	COG2890	protein-(glutamine-N5) methyltransferase activity
M9799_RS05185	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M9799_RS05190	COG1253	flavin adenine dinucleotide binding
M9799_RS05195	COG0741	lytic transglycosylase activity
M9799_RS05200	COG0442	prolyl-tRNA aminoacylation
M9799_RS05205	COG0494	nUDIX hydrolase
M9799_RS05210	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
M9799_RS05215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
M9799_RS05220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
M9799_RS05225	COG0261	This protein binds to 23S rRNA in the presence of protein L20
M9799_RS05230	COG0142	geranyltranstransferase activity
M9799_RS05260	COG0523	cobalamin synthesis protein
M9799_RS05265	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS05285	COG1522	sequence-specific DNA binding
M9799_RS05335	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M9799_RS05340	COG0237	dephospho-CoA kinase activity
M9799_RS05345	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
M9799_RS05350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M9799_RS05355	COG0494	nUDIX hydrolase
M9799_RS05365	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M9799_RS05390	COG2969	positive regulation of protein catabolic process
M9799_RS05395	COG0625	glutathione transferase activity
M9799_RS05400	COG2857	Cytochrome c1
M9799_RS05405	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
M9799_RS05410	COG0723	plastoquinol--plastocyanin reductase activity
M9799_RS05415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
M9799_RS05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M9799_RS05435	COG0805	protein transport
M9799_RS05440	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M9799_RS05445	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
M9799_RS05450	COG0537	adenosine 5'-monophosphoramidase activity
M9799_RS05460	COG0140	phosphoribosyl-ATP diphosphatase activity
M9799_RS05465	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M9799_RS05470	COG0107	imidazoleglycerol-phosphate synthase activity
M9799_RS05475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M9799_RS05485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
M9799_RS05495	COG0131	Imidazoleglycerol-phosphate dehydratase
M9799_RS05500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
M9799_RS05520	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M9799_RS05525	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M9799_RS05530	COG5007	Belongs to the BolA IbaG family
M9799_RS05535	COG0842	Transport permease protein
M9799_RS05540	COG1131	(ABC) transporter
M9799_RS05555	COG2853	Lipoprotein
M9799_RS05560	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M9799_RS05565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M9799_RS05570	COG1127	ABC transporter
M9799_RS05575	COG1126	abc transporter atp-binding protein
M9799_RS05580	COG0765	amino acid transport
M9799_RS05585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9799_RS05595	COG0069	glutamate synthase activity
M9799_RS05595	COG0067	glutamate synthase
M9799_RS05595	COG0070	glutamate synthase
M9799_RS05615	COG0232	Belongs to the dGTPase family. Type 2 subfamily
M9799_RS05620	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
M9799_RS05625	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
M9799_RS05665	COG1965	Belongs to the frataxin family
M9799_RS05675	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
M9799_RS05680	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
M9799_RS05685	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
M9799_RS05690	COG1333	cytochrome c biogenesis protein
M9799_RS05700	COG0218	Necessary for normal cell division and for the maintenance of normal septation
M9799_RS05705	COG2267	carboxylic ester hydrolase activity
M9799_RS05710	COG1560	Kdo2-lipid A biosynthetic process
M9799_RS05720	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
M9799_RS05735	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M9799_RS05740	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M9799_RS05740	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M9799_RS05745	COG1051	belongs to the nudix hydrolase family
M9799_RS05745	COG1056	cytidyltransferase-related domain
M9799_RS05760	COG5383	Protein conserved in bacteria
M9799_RS05765	COG0277	FAD linked oxidase domain protein
M9799_RS05775	COG0583	DNA-binding transcription factor activity
M9799_RS05790	COG2832	Protein of unknown function (DUF454)
M9799_RS05795	COG1511	domain protein
M9799_RS05795	COG3264	Mechanosensitive ion channel
M9799_RS05800	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
M9799_RS05805	COG0459	protein refolding
M9799_RS05810	COG0166	Belongs to the GPI family
M9799_RS05815	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M9799_RS05835	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
M9799_RS05840	COG1765	OsmC-like protein
M9799_RS05845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M9799_RS05850	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
M9799_RS05925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M9799_RS05950	COG1132	(ABC) transporter
M9799_RS05955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M9799_RS05955	COG1181	Belongs to the D-alanine--D-alanine ligase family
M9799_RS05960	COG0189	ligase activity
M9799_RS05960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M9799_RS05965	COG3045	CreA protein
M9799_RS05980	COG0443	Heat shock 70 kDa protein
M9799_RS06005	COG2208	phosphoserine phosphatase activity
M9799_RS06005	COG2770	Histidine kinase
M9799_RS06040	COG1366	Belongs to the anti-sigma-factor antagonist family
M9799_RS06045	COG4789	Type iii secretion
M9799_RS06140	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M9799_RS06145	COG4790	Type iii secretion
M9799_RS06150	COG4794	Type iii secretion
M9799_RS06155	COG4791	protein targeting
M9799_RS06160	COG4792	protein secretion
M9799_RS06185	COG3447	MASE1 domain protein
M9799_RS06185	COG5001	Diguanylate cyclase
M9799_RS06185	COG5002	protein histidine kinase activity
M9799_RS06225	COG1522	sequence-specific DNA binding
M9799_RS06235	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M9799_RS06240	COG0583	DNA-binding transcription factor activity
M9799_RS06245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M9799_RS06250	COG0739	heme binding
M9799_RS06255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M9799_RS06265	COG0316	Belongs to the HesB IscA family
M9799_RS06270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M9799_RS06275	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
M9799_RS06280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M9799_RS06285	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M9799_RS06290	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M9799_RS06295	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
M9799_RS06300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M9799_RS06305	COG2814	Major facilitator Superfamily
M9799_RS06310	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M9799_RS06320	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS06330	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS06360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M9799_RS06375	COG0477	Major facilitator Superfamily
M9799_RS06395	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS06405	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
M9799_RS06410	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M9799_RS06415	COG0025	NhaP-type Na H and K H
M9799_RS06425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M9799_RS06430	COG3012	SEC-C Motif Domain Protein
M9799_RS06435	COG1960	acyl-CoA dehydrogenase activity
M9799_RS06440	COG4221	oxidoreductase activity
M9799_RS06450	COG0183	Belongs to the thiolase family
M9799_RS06455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
M9799_RS06460	COG0288	reversible hydration of carbon dioxide
M9799_RS06465	COG1960	acyl-CoA dehydrogenase activity
M9799_RS06470	COG0789	Transcriptional regulator
M9799_RS06555	COG0488	(ABC) transporter
M9799_RS06560	COG2201	protein-glutamate methylesterase activity
M9799_RS06565	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
M9799_RS06570	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
M9799_RS06575	COG0835	chemotaxis
M9799_RS06580	COG2198	Histidine kinase
M9799_RS06580	COG0643	Histidine kinase
M9799_RS06585	COG0745	RESPONSE REGULATOR receiver
M9799_RS06610	COG1987	bacterial-type flagellum assembly
M9799_RS06615	COG1338	Plays a role in the flagellum-specific transport system
M9799_RS06620	COG3190	flagellar
M9799_RS06625	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
M9799_RS06635	COG1580	Controls the rotational direction of flagella during chemotaxis
M9799_RS06650	COG1157	protein secretion by the type III secretion system
M9799_RS06655	COG1317	bacterial-type flagellum organization
M9799_RS06670	COG1677	Flagellar hook-basal body complex protein FliE
M9799_RS06685	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
M9799_RS06695	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M9799_RS06710	COG0745	RESPONSE REGULATOR receiver
M9799_RS06715	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
M9799_RS06725	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
M9799_RS06760	COG1815	bacterial-type flagellum-dependent cell motility
M9799_RS06765	COG1558	bacterial-type flagellum-dependent cell motility
M9799_RS06775	COG1749	Flagellar hook protein flgE
M9799_RS06780	COG4787	bacterial-type flagellum-dependent cell motility
M9799_RS06795	COG1706	bacterial-type flagellum-dependent cell motility
M9799_RS06805	COG1256	bacterial-type flagellum assembly
M9799_RS06810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
M9799_RS06825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M9799_RS06845	COG0534	Mate efflux family protein
M9799_RS06865	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
M9799_RS06870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M9799_RS06885	COG0679	Auxin Efflux Carrier
M9799_RS06890	COG0210	DNA helicase
M9799_RS06915	COG0343	queuine tRNA-ribosyltransferase activity
M9799_RS06930	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M9799_RS06935	COG0395	ABC-type sugar transport system, permease component
M9799_RS06940	COG1176	ABC-type spermidine putrescine transport system, permease component I
M9799_RS06950	COG3842	ATPase activity
M9799_RS06980	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M9799_RS06985	COG1074	ATP-dependent DNA helicase activity
M9799_RS06990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M9799_RS07005	COG0765	amino acid transport
M9799_RS07010	COG0765	amino acid transport
M9799_RS07015	COG1126	abc transporter atp-binding protein
M9799_RS07035	COG2205	protein histidine kinase activity
M9799_RS07040	COG0745	RESPONSE REGULATOR receiver
M9799_RS07050	COG2204	response regulator
M9799_RS07055	COG5000	phosphorelay sensor kinase activity
M9799_RS07065	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
M9799_RS07065	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M9799_RS07075	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
M9799_RS07080	COG0085	RNA polymerase activity
M9799_RS07085	COG0222	ribosome binding
M9799_RS07090	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
M9799_RS07095	COG0081	regulation of translation
M9799_RS07100	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
M9799_RS07110	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
M9799_RS07120	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M9799_RS07150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS07195	COG0355	proton-transporting ATP synthase activity, rotational mechanism
M9799_RS07200	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
M9799_RS07205	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
M9799_RS07210	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
M9799_RS07215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
M9799_RS07220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
M9799_RS07230	COG0356	it plays a direct role in the translocation of protons across the membrane
M9799_RS07240	COG2921	Belongs to the UPF0250 family
M9799_RS07245	COG0321	lipoyl(octanoyl) transferase activity
M9799_RS07250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M9799_RS07255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M9799_RS07260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M9799_RS07270	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M9799_RS07275	COG0456	acetyltransferase
M9799_RS07280	COG0678	peroxiredoxin activity
M9799_RS07285	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
M9799_RS07290	COG0255	Belongs to the universal ribosomal protein uL29 family
M9799_RS07295	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
M9799_RS07300	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
M9799_RS07305	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
M9799_RS07310	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
M9799_RS07315	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
M9799_RS07320	COG0089	rRNA binding
M9799_RS07325	COG0088	Forms part of the polypeptide exit tunnel
M9799_RS07330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
M9799_RS07335	COG0051	transcription antitermination factor activity, RNA binding
M9799_RS07340	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
M9799_RS07345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
M9799_RS07350	COG0049	tRNA binding
M9799_RS07355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
M9799_RS07360	COG1686	Belongs to the peptidase S11 family
M9799_RS07365	COG2945	thiolester hydrolase activity
M9799_RS07380	COG1981	membrane
M9799_RS07390	COG0598	Magnesium transport protein CorA
M9799_RS07415	COG1127	ABC transporter
M9799_RS07420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M9799_RS07435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9799_RS07440	COG0765	amino acid transport
M9799_RS07455	COG0768	penicillin binding
M9799_RS07470	COG1077	Cell shape determining protein MreB Mrl
M9799_RS07475	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M9799_RS07480	COG0154	amidase activity
M9799_RS07485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M9799_RS07490	COG3620	sequence-specific DNA binding
M9799_RS07490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
M9799_RS07490	COG0617	tRNA 3'-terminal CCA addition
M9799_RS07515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
M9799_RS07520	COG0708	Exodeoxyribonuclease III
M9799_RS07535	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M9799_RS07545	COG0683	leucine binding
M9799_RS07570	COG0683	leucine binding
M9799_RS07580	COG0633	Ferredoxin
M9799_RS07590	COG4638	Rieske (2fe-2S)
M9799_RS07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M9799_RS07625	COG0745	RESPONSE REGULATOR receiver
M9799_RS07630	COG2205	protein histidine kinase activity
M9799_RS07640	COG1442	glycosyl transferase family 8
M9799_RS07640	COG1216	Glycosyl transferase, family 2
M9799_RS07690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M9799_RS07700	COG0386	Belongs to the glutathione peroxidase family
M9799_RS07710	COG0247	lactate metabolic process
M9799_RS07715	COG0277	FAD linked oxidase domain protein
M9799_RS07720	COG0004	ammonium transporteR
M9799_RS07725	COG0347	Belongs to the P(II) protein family
M9799_RS07740	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS07745	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M9799_RS07750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS07760	COG3386	PFAM SMP-30 Gluconolaconase
M9799_RS07775	COG0251	oxidation-reduction process
M9799_RS07785	COG0606	chelatase, subunit chli
M9799_RS07790	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS07810	COG1802	Transcriptional regulator
M9799_RS07815	COG3960	tartronate-semialdehyde synthase activity
M9799_RS07820	COG1063	alcohol dehydrogenase
M9799_RS07825	COG1024	Enoyl-CoA hydratase
M9799_RS07835	COG0028	Belongs to the TPP enzyme family
M9799_RS07840	COG0559	Belongs to the binding-protein-dependent transport system permease family
M9799_RS07865	COG2030	dehydratase
M9799_RS07895	COG0683	leucine binding
M9799_RS07905	COG3210	domain, Protein
M9799_RS07915	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS07940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M9799_RS07965	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M9799_RS07995	COG1960	acyl-CoA dehydrogenase activity
M9799_RS08000	COG1960	acyl-CoA dehydrogenase activity
M9799_RS08005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M9799_RS08015	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
M9799_RS08065	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M9799_RS08065	COG1199	ATP-dependent helicase activity
M9799_RS08070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M9799_RS08075	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
M9799_RS08085	COG0850	regulation of cytokinetic process
M9799_RS08090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M9799_RS08095	COG2233	PERMEase
M9799_RS08105	COG2050	protein possibly involved in aromatic compounds catabolism
M9799_RS08130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M9799_RS08140	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M9799_RS08145	COG2096	Adenosyltransferase
M9799_RS08150	COG0277	FAD linked oxidase domain protein
M9799_RS08155	COG2271	Major facilitator Superfamily
M9799_RS08160	COG0165	Argininosuccinate lyase
M9799_RS08165	COG0165	Argininosuccinate lyase
M9799_RS08170	COG1475	DNA binding
M9799_RS08180	COG1192	Involved in chromosome partitioning
M9799_RS08185	COG1280	lysine exporter protein (LysE YggA)
M9799_RS08190	COG0357	Ribosomal RNA small subunit methyltransferase G
M9799_RS08195	COG0445	tRNA wobble uridine modification
M9799_RS08200	COG0625	glutathione transferase activity
M9799_RS08205	COG1902	pentaerythritol trinitrate reductase activity
M9799_RS08210	COG0840	transmembrane signaling receptor activity
M9799_RS08230	COG0183	Belongs to the thiolase family
M9799_RS08235	COG2974	May be involved in recombination
M9799_RS08245	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M9799_RS08250	COG1199	ATP-dependent helicase activity
M9799_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS08255	COG0604	alcohol dehydrogenase
M9799_RS08255	COG3321	synthase
M9799_RS08260	COG0156	8-amino-7-oxononanoate synthase activity
M9799_RS08270	COG0861	Integral membrane protein TerC family
M9799_RS08275	COG1368	sulfuric ester hydrolase activity
M9799_RS08295	COG0438	transferase activity, transferring glycosyl groups
M9799_RS08305	COG0438	transferase activity, transferring glycosyl groups
M9799_RS08320	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
M9799_RS08370	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
M9799_RS08375	COG3829	transcription factor binding
M9799_RS08385	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M9799_RS08400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9799_RS08405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS08410	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M9799_RS08420	COG1802	Transcriptional regulator
M9799_RS08430	COG0840	transmembrane signaling receptor activity
M9799_RS08440	COG1716	ATPase activity
M9799_RS08440	COG5001	Diguanylate cyclase
M9799_RS08475	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS08505	COG1690	Belongs to the RtcB family
M9799_RS08525	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M9799_RS08530	COG0230	Belongs to the bacterial ribosomal protein bL34 family
M9799_RS08540	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
M9799_RS08545	COG0706	membrane insertase activity
M9799_RS08550	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
M9799_RS08565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
M9799_RS08575	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M9799_RS08585	COG0300	oxidoreductase activity
M9799_RS08590	COG0724	RNA recognition motif
M9799_RS08600	COG0724	RNA recognition motif
M9799_RS08605	COG2119	membrane
M9799_RS08610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M9799_RS08625	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M9799_RS08635	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
M9799_RS08640	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M9799_RS08645	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M9799_RS08680	COG0482	sulfurtransferase activity
M9799_RS08685	COG5507	3-demethylubiquinone-9 3-methyltransferase
M9799_RS08700	COG0629	single-stranded DNA binding
M9799_RS08705	COG2814	Major facilitator Superfamily
M9799_RS08720	COG0584	glycerophosphoryl diester phosphodiesterase
M9799_RS08730	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS08735	COG0583	DNA-binding transcription factor activity
M9799_RS08740	COG0284	orotidine-5'-phosphate decarboxylase activity
M9799_RS08745	COG0126	phosphoglycerate kinase activity
M9799_RS08760	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
M9799_RS08770	COG0242	peptide deformylase activity
M9799_RS08780	COG0758	DNA mediated transformation
M9799_RS08795	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M9799_RS08800	COG1862	Preprotein translocase
M9799_RS08810	COG1522	sequence-specific DNA binding
M9799_RS08815	COG2814	Major facilitator Superfamily
M9799_RS08820	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
M9799_RS08855	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M9799_RS08860	COG0625	glutathione transferase activity
M9799_RS08880	COG0861	Integral membrane protein TerC family
M9799_RS08890	COG1950	PFAM Membrane protein of
M9799_RS08895	COG4783	chaperone-mediated protein folding
M9799_RS08900	COG0315	cyclic pyranopterin monophosphate synthase activity
M9799_RS08925	COG0631	protein serine/threonine phosphatase activity
M9799_RS08930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
M9799_RS08935	COG0045	succinate-CoA ligase (ADP-forming) activity
M9799_RS08940	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
M9799_RS08945	COG2137	regulation of response to DNA damage stimulus
M9799_RS08950	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
M9799_RS08965	COG0642	Histidine kinase
M9799_RS09000	COG0551	DNA topoisomerase type I activity
M9799_RS09000	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
M9799_RS09005	COG2365	Tyrosine phosphatase family
M9799_RS09015	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M9799_RS09030	COG3148	PFAM DTW domain containing protein
M9799_RS09040	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
M9799_RS09040	COG2755	lipolytic protein G-D-S-L family
M9799_RS09050	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS09060	COG0625	glutathione transferase activity
M9799_RS09075	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
M9799_RS09105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M9799_RS09110	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M9799_RS09115	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M9799_RS09120	COG0006	proline dipeptidase activity
M9799_RS09130	COG0469	pyruvate kinase activity
M9799_RS09150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M9799_RS09155	COG0598	Magnesium transport protein CorA
M9799_RS09165	COG0456	acetyltransferase
M9799_RS09170	COG1214	PFAM Peptidase M22, glycoprotease
M9799_RS09175	COG2027	D-alanyl-D-alanine carboxypeptidase
M9799_RS09190	COG0009	L-threonylcarbamoyladenylate synthase
M9799_RS09195	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M9799_RS09200	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
M9799_RS09205	COG3118	belongs to the thioredoxin family
M9799_RS09210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
M9799_RS09215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
M9799_RS09225	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
M9799_RS09230	COG0735	belongs to the Fur family
M9799_RS09235	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M9799_RS09240	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
M9799_RS09255	COG0668	transmembrane transport
M9799_RS09260	COG0495	leucyl-tRNA aminoacylation
M9799_RS09275	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
M9799_RS09280	COG0569	domain protein
M9799_RS09285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M9799_RS09295	COG3158	transport of potassium into the cell
M9799_RS09300	COG0189	ligase activity
M9799_RS09355	COG0121	glutamine amidotransferase
M9799_RS09360	COG1942	4-Oxalocrotonate Tautomerase
M9799_RS09370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M9799_RS09385	COG0018	arginyl-trna synthetase
M9799_RS09395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M9799_RS09400	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M9799_RS09405	COG1137	ATPase activity
M9799_RS09410	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
M9799_RS09425	COG0653	protein targeting
M9799_RS09430	COG0659	secondary active sulfate transmembrane transporter activity
M9799_RS09435	COG1546	Belongs to the CinA family
M9799_RS09440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M9799_RS09450	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
M9799_RS09465	COG2967	ApaG domain
M9799_RS09470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M9799_RS09475	COG0546	phosphoglycolate phosphatase activity
M9799_RS09490	COG0512	Glutamine amidotransferase of anthranilate synthase
M9799_RS09495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M9799_RS09500	COG0134	indole-3-glycerol-phosphate synthase activity
M9799_RS09505	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
M9799_RS09515	COG4607	ABC-type enterochelin transport system periplasmic component
M9799_RS09520	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS09525	COG4605	iron ion homeostasis
M9799_RS09530	COG4604	ABC transporter, ATP-binding protein
M9799_RS09535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
M9799_RS09545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M9799_RS09555	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M9799_RS09565	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M9799_RS09575	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
M9799_RS09580	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
M9799_RS09585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
M9799_RS09590	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
M9799_RS09595	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
M9799_RS09600	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
M9799_RS09605	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
M9799_RS09610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
M9799_RS09615	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
M9799_RS09620	COG1841	ribosomal large subunit assembly
M9799_RS09625	COG0200	Binds to the 23S rRNA
M9799_RS09630	COG0201	protein transport
M9799_RS09635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
M9799_RS09640	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
M9799_RS09645	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
M9799_RS09650	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
M9799_RS09655	COG0202	RNA polymerase activity
M9799_RS09660	COG0203	ribosomal protein L17
M9799_RS09670	COG0443	Heat shock 70 kDa protein
M9799_RS09680	COG0792	nuclease activity
M9799_RS09685	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
M9799_RS09690	COG2823	Periplasmic or secreted lipoprotein
M9799_RS09695	COG2084	Dehydrogenase
M9799_RS09705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9799_RS09730	COG0545	Peptidyl-prolyl cis-trans isomerase
M9799_RS09735	COG3604	Transcriptional regulator
M9799_RS09740	COG1017	nitric oxide dioxygenase activity
M9799_RS09740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M9799_RS09750	COG2733	membrane
M9799_RS09755	COG4771	TonB-dependent receptor
M9799_RS09770	COG1252	NADH dehydrogenase
M9799_RS09775	COG0277	FAD linked oxidase domain protein
M9799_RS09780	COG0277	FAD linked oxidase domain protein
M9799_RS09785	COG0583	DNA-binding transcription factor activity
M9799_RS09830	COG1979	alcohol dehydrogenase
M9799_RS09835	COG0243	molybdopterin cofactor binding
M9799_RS09840	COG1473	amidohydrolase
M9799_RS09865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
M9799_RS09910	COG1022	Amp-dependent synthetase and ligase
M9799_RS09915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9799_RS09920	COG1187	pseudouridine synthase activity
M9799_RS09930	COG0326	Molecular chaperone. Has ATPase activity
M9799_RS09965	COG0559	Belongs to the binding-protein-dependent transport system permease family
M9799_RS09980	COG3964	amidohydrolase
M9799_RS10000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M9799_RS10005	COG1414	Transcriptional regulator
M9799_RS10010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M9799_RS10015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS10025	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9799_RS10030	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
M9799_RS10035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M9799_RS10040	COG5001	Diguanylate cyclase
M9799_RS10040	COG3300	MHYT domain
M9799_RS10045	COG0513	Belongs to the DEAD box helicase family
M9799_RS10050	COG1490	D-aminoacyl-tRNA deacylase activity
M9799_RS10055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
M9799_RS10060	COG1702	phosphate starvation-inducible protein PhoH
M9799_RS10065	COG0632	four-way junction helicase activity
M9799_RS10070	COG2255	four-way junction helicase activity
M9799_RS10090	COG1253	flavin adenine dinucleotide binding
M9799_RS10100	COG0588	phosphoglycerate mutase activity
M9799_RS10110	COG0747	negative chemotaxis
M9799_RS10120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M9799_RS10135	COG0037	tRNA processing
M9799_RS10170	COG1012	belongs to the aldehyde dehydrogenase family
M9799_RS10175	COG0617	tRNA 3'-terminal CCA addition
M9799_RS10185	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M9799_RS10190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M9799_RS10205	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS10215	COG3186	Phenylalanine-4-hydroxylase
M9799_RS10225	COG1522	sequence-specific DNA binding
M9799_RS10240	COG0815	Transfers the fatty acyl group on membrane lipoproteins
M9799_RS10245	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
M9799_RS10270	COG0438	transferase activity, transferring glycosyl groups
M9799_RS10270	COG1216	Glycosyl transferase, family 2
M9799_RS10275	COG1011	Hydrolase
M9799_RS10300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
M9799_RS10325	COG4260	virion core protein, lumpy skin disease virus
M9799_RS10330	COG0752	glycyl-tRNA synthetase alpha subunit
M9799_RS10335	COG0751	glycine-tRNA ligase activity
M9799_RS10340	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
M9799_RS10345	COG0204	Acyl-transferase
M9799_RS10360	COG1652	LysM domain
M9799_RS10365	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
M9799_RS10375	COG1091	dTDP-4-dehydrorhamnose reductase activity
M9799_RS10400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
M9799_RS10405	COG0745	RESPONSE REGULATOR receiver
M9799_RS10410	COG0642	Histidine kinase
M9799_RS10415	COG1309	transcriptional regulator
M9799_RS10430	COG1960	acyl-CoA dehydrogenase activity
M9799_RS10440	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9799_RS10440	COG1024	Enoyl-CoA hydratase
M9799_RS10445	COG0183	Belongs to the thiolase family
M9799_RS10455	COG1024	Enoyl-CoA hydratase
M9799_RS10465	COG1607	acyl-coa hydrolase
M9799_RS10470	COG5265	(ABC) transporter
M9799_RS10475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS10485	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS10490	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS10490	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
M9799_RS10495	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
M9799_RS10500	COG0583	DNA-binding transcription factor activity
M9799_RS10510	COG0765	amino acid transport
M9799_RS10515	COG0765	amino acid transport
M9799_RS10520	COG1126	abc transporter atp-binding protein
M9799_RS10525	COG0418	dihydroorotase activity
M9799_RS10535	COG0501	Belongs to the peptidase M48B family
M9799_RS10540	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
M9799_RS10545	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
M9799_RS10555	COG1132	(ABC) transporter
M9799_RS10570	COG1187	pseudouridine synthase activity
M9799_RS10575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M9799_RS10590	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
M9799_RS10600	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M9799_RS10605	COG0523	cobalamin synthesis protein
M9799_RS10620	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
M9799_RS10625	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
M9799_RS10635	COG2001	Belongs to the MraZ family
M9799_RS10640	COG0275	rRNA processing
M9799_RS10645	COG3116	cell division
M9799_RS10655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M9799_RS10660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M9799_RS10665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
M9799_RS10670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
M9799_RS10675	COG0772	Belongs to the SEDS family
M9799_RS10680	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
M9799_RS10685	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M9799_RS10690	COG1181	Belongs to the D-alanine--D-alanine ligase family
M9799_RS10695	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M9799_RS10710	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
M9799_RS10725	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
M9799_RS10735	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
M9799_RS10745	COG0557	exoribonuclease II activity
M9799_RS10750	COG3150	esterase
M9799_RS10755	COG0772	Belongs to the SEDS family
M9799_RS10760	COG0312	modulator of DNA gyrase
M9799_RS10770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M9799_RS10775	COG3098	single-species biofilm formation
M9799_RS10785	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M9799_RS10795	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
M9799_RS10800	COG0511	ligase activity, forming carbon-carbon bonds
M9799_RS10805	COG0439	Biotin carboxylase
M9799_RS10810	COG2264	protein methyltransferase activity
M9799_RS10825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M9799_RS10845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M9799_RS10850	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M9799_RS10850	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
M9799_RS10880	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M9799_RS10885	COG0791	NLP P60 protein
M9799_RS10890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
M9799_RS10900	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M9799_RS10905	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M9799_RS10925	COG2814	Major facilitator Superfamily
M9799_RS10930	COG3622	Belongs to the hyi family
M9799_RS10960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M9799_RS10965	COG4172	Belongs to the ABC transporter superfamily
M9799_RS11025	COG0612	Peptidase, M16
M9799_RS11040	COG1024	Enoyl-CoA hydratase
M9799_RS11055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M9799_RS11065	COG0012	GTP binding
M9799_RS11070	COG2814	Major facilitator Superfamily
M9799_RS11150	COG1238	metal cluster binding
M9799_RS11165	COG0784	Response regulator, receiver
M9799_RS11165	COG2205	protein histidine kinase activity
M9799_RS11170	COG2205	protein histidine kinase activity
M9799_RS11180	COG2172	sigma factor antagonist activity
M9799_RS11185	COG1366	Belongs to the anti-sigma-factor antagonist family
M9799_RS11190	COG1366	Belongs to the anti-sigma-factor antagonist family
M9799_RS11195	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M9799_RS11200	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M9799_RS11205	COG0138	bifunctional purine biosynthesis protein purh
M9799_RS11215	COG0531	amino acid
M9799_RS11220	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
M9799_RS11230	COG1773	rubredoxin
M9799_RS11240	COG0415	Belongs to the DNA photolyase family
M9799_RS11245	COG1678	Uncharacterized ACR, COG1678
M9799_RS11250	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M9799_RS11255	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
M9799_RS11260	COG0540	Belongs to the ATCase OTCase family
M9799_RS11265	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
M9799_RS11275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9799_RS11280	COG4597	amino acid ABC transporter
M9799_RS11285	COG0765	amino acid transport
M9799_RS11290	COG1126	abc transporter atp-binding protein
M9799_RS11295	COG2827	Endonuclease containing a URI domain
M9799_RS11300	COG3842	ATPase activity
M9799_RS11305	COG1178	ABC-type Fe3 transport system permease component
M9799_RS11335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9799_RS11345	COG0251	oxidation-reduction process
M9799_RS11375	COG3152	Membrane
M9799_RS11415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M9799_RS11430	COG1280	lysine exporter protein (LysE YggA)
M9799_RS11440	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M9799_RS11445	COG1040	competence protein
M9799_RS11450	COG2226	methyltransferase
M9799_RS11460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M9799_RS11500	COG1999	signal sequence binding
M9799_RS11505	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS11510	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
M9799_RS11515	COG1324	tolerance protein
M9799_RS11525	COG0612	Peptidase, M16
M9799_RS11530	COG0612	Peptidase, M16
M9799_RS11535	COG0742	ribosomal rna small subunit methyltransferase
M9799_RS11540	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
M9799_RS11565	COG4585	Histidine kinase
M9799_RS11570	COG2197	response regulator
M9799_RS11580	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
M9799_RS11585	COG0793	Belongs to the peptidase S41A family
M9799_RS11590	COG0588	phosphoglycerate mutase activity
M9799_RS11595	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
M9799_RS11605	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
M9799_RS11610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
M9799_RS11620	COG0583	DNA-binding transcription factor activity
M9799_RS11630	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M9799_RS11645	COG2807	transmembrane transport
M9799_RS11675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9799_RS11675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9799_RS11685	COG0489	protein tyrosine kinase activity
M9799_RS11690	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M9799_RS11715	COG2003	Belongs to the UPF0758 family
M9799_RS11720	COG1047	Peptidyl-prolyl cis-trans
M9799_RS11725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
M9799_RS11730	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
M9799_RS11755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M9799_RS11760	COG1758	RNA polymerase activity
M9799_RS11765	COG0194	GDP metabolic process
M9799_RS11770	COG1561	YicC-like family, N-terminal region
M9799_RS11785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
M9799_RS11790	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M9799_RS11815	COG1802	Transcriptional regulator
M9799_RS11815	COG4626	Terminase
M9799_RS11825	COG0066	3-isopropylmalate dehydratase activity
M9799_RS11830	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M9799_RS11855	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
M9799_RS11860	COG1122	ATPase activity
M9799_RS11870	COG1268	BioY protein
M9799_RS11875	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS11880	COG0183	Belongs to the thiolase family
M9799_RS11900	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS11905	COG1960	acyl-CoA dehydrogenase activity
M9799_RS11910	COG0583	DNA-binding transcription factor activity
M9799_RS11920	COG4829	muconolactone delta-isomerase
M9799_RS11935	COG0583	DNA-binding transcription factor activity
M9799_RS11945	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS11965	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS11970	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS11985	COG0559	Belongs to the binding-protein-dependent transport system permease family
M9799_RS12035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M9799_RS12075	COG2200	EAL domain
M9799_RS12075	COG2199	diguanylate cyclase activity
M9799_RS12080	COG0583	DNA-binding transcription factor activity
M9799_RS12090	COG1473	amidohydrolase
M9799_RS12115	COG2099	Precorrin-6x reductase
M9799_RS12130	COG2875	Belongs to the precorrin methyltransferase family
M9799_RS12145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M9799_RS12145	COG2205	protein histidine kinase activity
M9799_RS12150	COG2819	hydrolase of the alpha beta superfamily
M9799_RS12160	COG3712	iron ion homeostasis
M9799_RS12165	COG1595	DNA-templated transcription, initiation
M9799_RS12175	COG2301	Belongs to the HpcH HpaI aldolase family
M9799_RS12185	COG2186	Transcriptional regulator
M9799_RS12190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS12195	COG1960	acyl-CoA dehydrogenase activity
M9799_RS12220	COG1002	Type II restriction enzyme, methylase subunits
M9799_RS12225	COG1061	Type III restriction enzyme res subunit
M9799_RS12230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M9799_RS12250	COG2003	Belongs to the UPF0758 family
M9799_RS12260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
M9799_RS12265	COG0830	nickel cation binding
M9799_RS12270	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
M9799_RS12280	COG0804	urea catabolic process
M9799_RS12285	COG0832	Belongs to the urease beta subunit family
M9799_RS12295	COG0831	urea catabolic process
M9799_RS12300	COG2198	Histidine kinase
M9799_RS12300	COG5002	protein histidine kinase activity
M9799_RS12300	COG0784	Response regulator, receiver
M9799_RS12315	COG4133	protoheme IX ABC transporter activity
M9799_RS12355	COG0829	nickel cation binding
M9799_RS12360	COG0590	tRNA wobble adenosine to inosine editing
M9799_RS12365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS12370	COG1116	anion transmembrane transporter activity
M9799_RS12375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M9799_RS12380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M9799_RS12385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M9799_RS12390	COG0280	phosphate acetyltransferase
M9799_RS12390	COG0281	malic enzyme
M9799_RS12420	COG2186	Transcriptional regulator
M9799_RS12480	COG3447	MASE1 domain protein
M9799_RS12480	COG5001	Diguanylate cyclase
M9799_RS12480	COG5002	protein histidine kinase activity
M9799_RS12485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M9799_RS12495	COG3845	ABC transporter
M9799_RS12500	COG4603	Belongs to the binding-protein-dependent transport system permease family
M9799_RS12530	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M9799_RS12540	COG0402	S-adenosylhomocysteine deaminase activity
M9799_RS12545	COG0717	Belongs to the dCTP deaminase family
M9799_RS12560	COG2321	neutral zinc metallopeptidase
M9799_RS12565	COG0513	Belongs to the DEAD box helicase family
M9799_RS12575	COG2721	sulfolactate sulfo-lyase activity
M9799_RS12580	COG1802	Transcriptional regulator
M9799_RS12590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M9799_RS12595	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS12605	COG1012	belongs to the aldehyde dehydrogenase family
M9799_RS12610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M9799_RS12615	COG1253	flavin adenine dinucleotide binding
M9799_RS12620	COG2916	Histone family protein nucleoid-structuring protein H-NS
M9799_RS12625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M9799_RS12635	COG3483	tryptophan 2,3-dioxygenase activity
M9799_RS12655	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
M9799_RS12665	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
M9799_RS12670	COG1113	amino acid transport
M9799_RS12675	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
M9799_RS12680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M9799_RS12690	COG0268	Binds directly to 16S ribosomal RNA
M9799_RS12695	COG0728	peptidoglycan biosynthetic process
M9799_RS12710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
M9799_RS12715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
M9799_RS12720	COG0560	Phosphoserine phosphatase
M9799_RS12725	COG0617	tRNA 3'-terminal CCA addition
M9799_RS12730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M9799_RS12740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M9799_RS12740	COG0543	2 iron, 2 sulfur cluster binding
M9799_RS12775	COG0840	transmembrane signaling receptor activity
M9799_RS12825	COG0513	Belongs to the DEAD box helicase family
M9799_RS12835	COG1196	nuclear chromosome segregation
M9799_RS12905	COG0425	Belongs to the sulfur carrier protein TusA family
M9799_RS12910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M9799_RS12915	COG0525	valine-tRNA ligase activity
M9799_RS12935	COG3038	cytochrome b561
M9799_RS12955	COG0181	hydroxymethylbilane synthase activity
M9799_RS12960	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
M9799_RS12965	COG1289	transmembrane transporter activity
M9799_RS12995	COG1722	exodeoxyribonuclease VII activity
M9799_RS13005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
M9799_RS13010	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
M9799_RS13015	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
M9799_RS13025	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS13040	COG1968	undecaprenyl-diphosphatase activity
M9799_RS13045	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS13060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
M9799_RS13075	COG0483	inositol monophosphate 1-phosphatase activity
M9799_RS13085	COG1045	serine acetyltransferase
M9799_RS13110	COG2159	amidohydrolase
M9799_RS13115	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
M9799_RS13120	COG0840	transmembrane signaling receptor activity
M9799_RS13130	COG0521	Mo-molybdopterin cofactor biosynthetic process
M9799_RS13135	COG3028	Belongs to the UPF0307 family
M9799_RS13140	COG0312	modulator of DNA gyrase
M9799_RS13150	COG0828	Belongs to the bacterial ribosomal protein bS21 family
M9799_RS13155	COG2081	HI0933 family
M9799_RS13160	COG1607	acyl-coa hydrolase
M9799_RS13170	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M9799_RS13180	COG3210	domain, Protein
M9799_RS13195	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
M9799_RS13220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS13225	COG0577	efflux transmembrane transporter activity
M9799_RS13225	COG1136	(ABC) transporter
M9799_RS13230	COG1136	(ABC) transporter
M9799_RS13230	COG0577	efflux transmembrane transporter activity
M9799_RS13240	COG2951	lytic endotransglycosylase activity
M9799_RS13255	COG0714	Associated with various cellular activities
M9799_RS13265	COG1024	Enoyl-CoA hydratase
M9799_RS13270	COG3264	Mechanosensitive ion channel
M9799_RS13270	COG1511	domain protein
M9799_RS13290	COG1960	acyl-CoA dehydrogenase activity
M9799_RS13310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M9799_RS13315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
M9799_RS13320	COG0372	Belongs to the citrate synthase family
M9799_RS13325	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M9799_RS13330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M9799_RS13335	COG1053	succinate dehydrogenase
M9799_RS13345	COG2009	succinate dehydrogenase
M9799_RS13350	COG2188	Transcriptional regulator
M9799_RS13355	COG0039	L-malate dehydrogenase activity
M9799_RS13360	COG4106	trans-aconitate 2-methyltransferase activity
M9799_RS13380	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M9799_RS13395	COG0405	Gamma-glutamyltransferase
M9799_RS13400	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M9799_RS13405	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS13410	COG1802	Transcriptional regulator
M9799_RS13420	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M9799_RS13445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M9799_RS13450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS13455	COG0129	dihydroxy-acid dehydratase activity
M9799_RS13465	COG1902	pentaerythritol trinitrate reductase activity
M9799_RS13475	COG0826	peptidase U32
M9799_RS13495	COG0824	Thioesterase
M9799_RS13500	COG0436	Aminotransferase
M9799_RS13505	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
M9799_RS13510	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
M9799_RS13525	COG2918	glutathione biosynthetic process
M9799_RS13540	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
M9799_RS13545	COG1473	amidohydrolase
M9799_RS13550	COG1285	pathogenesis
M9799_RS13565	COG0564	pseudouridine synthase activity
M9799_RS13590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS13600	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
M9799_RS13605	COG0583	DNA-binding transcription factor activity
M9799_RS13630	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
M9799_RS13635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M9799_RS13645	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
M9799_RS13650	COG0596	Alpha beta hydrolase
M9799_RS13685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M9799_RS13705	COG0215	cysteine-tRNA ligase activity
M9799_RS13715	COG0825	malonyl-CoA metabolic process
M9799_RS13720	COG0037	tRNA processing
M9799_RS13790	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M9799_RS13800	COG3300	MHYT domain
M9799_RS13800	COG5001	Diguanylate cyclase
M9799_RS13810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M9799_RS13815	COG1116	anion transmembrane transporter activity
M9799_RS13820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS13835	COG1063	alcohol dehydrogenase
M9799_RS13910	COG1187	pseudouridine synthase activity
M9799_RS13920	COG0402	S-adenosylhomocysteine deaminase activity
M9799_RS13930	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M9799_RS13935	COG0642	Histidine kinase
M9799_RS13945	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS13980	COG1522	sequence-specific DNA binding
M9799_RS13985	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
M9799_RS13995	COG0583	DNA-binding transcription factor activity
M9799_RS14010	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
M9799_RS14015	COG1562	ergosterol biosynthetic process
M9799_RS14020	COG0513	Belongs to the DEAD box helicase family
M9799_RS14035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M9799_RS14065	COG0544	peptidyl-prolyl cis-trans isomerase activity
M9799_RS14070	COG0740	serine-type endopeptidase activity
M9799_RS14075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
M9799_RS14080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
M9799_RS14160	COG0583	DNA-binding transcription factor activity
M9799_RS14170	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS14175	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS14230	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS14245	COG1230	cation diffusion facilitator family transporter
M9799_RS14255	COG4166	transmembrane transport
M9799_RS14260	COG4174	ABC transporter (Permease)
M9799_RS14265	COG4239	(ABC) transporter, permease
M9799_RS14270	COG4172	Belongs to the ABC transporter superfamily
M9799_RS14275	COG3040	lipid binding
M9799_RS14280	COG1132	(ABC) transporter
M9799_RS14330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M9799_RS14330	COG2010	Cytochrome c
M9799_RS14340	COG0779	Required for maturation of 30S ribosomal subunits
M9799_RS14345	COG0195	Participates in both transcription termination and antitermination
M9799_RS14350	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
M9799_RS14355	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
M9799_RS14360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M9799_RS14370	COG1024	Enoyl-CoA hydratase
M9799_RS14375	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
M9799_RS14380	COG2867	negative regulation of translational initiation
M9799_RS14400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M9799_RS14400	COG0519	Catalyzes the synthesis of GMP from XMP
M9799_RS14415	COG1045	serine acetyltransferase
M9799_RS14430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS14445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M9799_RS14450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS14480	COG0137	argininosuccinate synthase activity
M9799_RS14485	COG3123	guanosine phosphorylase activity
M9799_RS14495	COG1393	Belongs to the ArsC family
M9799_RS14500	COG0285	dihydrofolate synthase activity
M9799_RS14525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M9799_RS14580	COG1850	ribulose-bisphosphate carboxylase activity
M9799_RS14590	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS14595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS14600	COG1609	Transcriptional regulator
M9799_RS14615	COG1840	ABC-type Fe3 transport system, periplasmic component
M9799_RS14625	COG0824	Thioesterase
M9799_RS14635	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
M9799_RS14655	COG1611	Belongs to the LOG family
M9799_RS14660	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
M9799_RS14670	COG2212	antiporter activity
M9799_RS14675	COG1863	multisubunit Na H antiporter MnhE subunit
M9799_RS14680	COG0651	ATP synthesis coupled electron transport
M9799_RS14685	COG1006	Multisubunit Na H antiporter MnhC subunit
M9799_RS14690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M9799_RS14690	COG2111	Na H antiporter
M9799_RS14695	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
M9799_RS14715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M9799_RS14725	COG0077	Prephenate dehydratase
M9799_RS14725	COG1605	Chorismate mutase
M9799_RS14730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
M9799_RS14745	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M9799_RS14785	COG0402	S-adenosylhomocysteine deaminase activity
M9799_RS14825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS14860	COG1393	Belongs to the ArsC family
M9799_RS14865	COG0431	NADPH-dependent FMN reductase
M9799_RS14900	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS14905	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS14920	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS14935	COG2223	nitrite transmembrane transporter activity
M9799_RS14980	COG1116	anion transmembrane transporter activity
M9799_RS14985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS14995	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS15020	COG2199	diguanylate cyclase activity
M9799_RS15020	COG2203	Gaf domain
M9799_RS15095	COG0243	molybdopterin cofactor binding
M9799_RS15100	COG2146	nitrite reductase [NAD(P)H] activity
M9799_RS15105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M9799_RS15110	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M9799_RS15110	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M9799_RS15110	COG0506	proline dehydrogenase activity
M9799_RS15130	COG0405	Gamma-glutamyltransferase
M9799_RS15145	COG1116	anion transmembrane transporter activity
M9799_RS15150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS15155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M9799_RS15160	COG3707	response regulator
M9799_RS15165	COG0583	DNA-binding transcription factor activity
M9799_RS15190	COG4993	Dehydrogenase
M9799_RS15195	COG0783	Belongs to the Dps family
M9799_RS15210	COG0720	synthase
M9799_RS15215	COG0602	queuosine metabolic process
M9799_RS15230	COG1304	FMN binding
M9799_RS15240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M9799_RS15245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS15250	COG0583	DNA-binding transcription factor activity
M9799_RS15255	COG0655	NAD(P)H dehydrogenase (quinone) activity
M9799_RS15285	COG0529	Catalyzes the synthesis of activated sulfate
M9799_RS15300	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
M9799_RS15305	COG0308	aminopeptidase N
M9799_RS15325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M9799_RS15340	COG2022	thiamine diphosphate biosynthetic process
M9799_RS15345	COG2104	thiamine diphosphate biosynthetic process
M9799_RS15355	COG4303	Ethanolamine ammonia lyase large subunit
M9799_RS15360	COG4302	ethanolamine ammonia-lyase activity
M9799_RS15365	COG0351	phosphomethylpyrimidine kinase
M9799_RS15385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M9799_RS15395	COG2917	probably involved in intracellular septation
M9799_RS15400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
M9799_RS15405	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M9799_RS15410	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS15420	COG0559	Belongs to the binding-protein-dependent transport system permease family
M9799_RS15430	COG0411	ABC transporter
M9799_RS15440	COG1024	Enoyl-CoA hydratase
M9799_RS15440	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9799_RS15445	COG0183	Belongs to the thiolase family
M9799_RS15450	COG1960	acyl-CoA dehydrogenase activity
M9799_RS15455	COG0745	RESPONSE REGULATOR receiver
M9799_RS15460	COG0642	Histidine kinase
M9799_RS15475	COG3639	organic phosphonate transmembrane transporter activity
M9799_RS15480	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
M9799_RS15485	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
M9799_RS15495	COG2814	Major facilitator Superfamily
M9799_RS15510	COG2130	NADP-dependent
M9799_RS15525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M9799_RS15530	COG1538	Outer membrane efflux protein
M9799_RS15560	COG2183	response to ionizing radiation
M9799_RS15570	COG0628	permease
M9799_RS15580	COG0657	acetylesterase activity
M9799_RS15585	COG2153	protein acetylation
M9799_RS15590	COG0354	folic acid binding
M9799_RS15595	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M9799_RS15600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
M9799_RS15605	COG0470	DNA polymerase III
M9799_RS15615	COG0084	hydrolase, TatD family'
M9799_RS15645	COG0579	oxidoreductase
M9799_RS15655	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M9799_RS15665	COG2885	chlorophyll binding
M9799_RS15670	COG0823	Involved in the tonB-independent uptake of proteins
M9799_RS15675	COG1132	(ABC) transporter
M9799_RS15690	COG3276	selenocysteine insertion sequence binding
M9799_RS15705	COG2864	formate dehydrogenase
M9799_RS15710	COG0437	4 iron, 4 sulfur cluster binding
M9799_RS15720	COG0628	permease
M9799_RS15725	COG0567	Dehydrogenase, E1 component
M9799_RS15730	COG0508	dehydrogenase complex catalyzes the overall conversion of
M9799_RS15735	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9799_RS15740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M9799_RS15760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M9799_RS15770	COG0563	adenylate kinase activity
M9799_RS15780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
M9799_RS15785	COG2835	tetraacyldisaccharide 4'-kinase activity
M9799_RS15790	COG1663	tetraacyldisaccharide 4'-kinase activity
M9799_RS15800	COG0811	peptide transport
M9799_RS15805	COG1570	exodeoxyribonuclease VII activity
M9799_RS15810	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M9799_RS15840	COG0243	molybdopterin cofactor binding
M9799_RS15850	COG1473	amidohydrolase
M9799_RS15885	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
M9799_RS15890	COG1280	lysine exporter protein (LysE YggA)
M9799_RS15915	COG1960	acyl-CoA dehydrogenase activity
M9799_RS15940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
M9799_RS15950	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
M9799_RS15955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M9799_RS15970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9799_RS15975	COG1739	Uncharacterized protein family UPF0029
M9799_RS15990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS15995	COG1414	Transcriptional regulator
M9799_RS16005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M9799_RS16010	COG0183	Belongs to the thiolase family
M9799_RS16030	COG0556	nucleotide-excision repair
M9799_RS16035	COG1959	2 iron, 2 sulfur cluster binding
M9799_RS16040	COG1104	cysteine desulfurase activity
M9799_RS16045	COG0822	iron-sulfur transferase activity
M9799_RS16050	COG0316	Belongs to the HesB IscA family
M9799_RS16060	COG0443	Heat shock 70 kDa protein
M9799_RS16065	COG0633	Ferredoxin
M9799_RS16115	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS16120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS16125	COG1960	acyl-CoA dehydrogenase activity
M9799_RS16130	COG1960	acyl-CoA dehydrogenase activity
M9799_RS16155	COG0579	oxidoreductase
M9799_RS16175	COG0167	dihydroorotate dehydrogenase activity
M9799_RS16180	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
M9799_RS16195	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
M9799_RS16200	COG4566	intracellular signal transduction
M9799_RS16210	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
M9799_RS16215	COG0508	dehydrogenase complex catalyzes the overall conversion of
M9799_RS16220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M9799_RS16245	COG0791	NLP P60 protein
M9799_RS16265	COG1538	Outer membrane efflux protein
M9799_RS16270	COG1054	Belongs to the UPF0176 family
M9799_RS16290	COG1309	transcriptional regulator
M9799_RS16325	COG0259	pyridoxamine-phosphate oxidase activity
M9799_RS16355	COG0346	lactoylglutathione lyase activity
M9799_RS16380	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
M9799_RS16410	COG1764	response to oxidative stress
M9799_RS16420	COG1024	Enoyl-CoA hydratase
M9799_RS16420	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9799_RS16440	COG4770	biotin carboxylase activity
M9799_RS16445	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M9799_RS16450	COG1703	isobutyryl-CoA mutase activity
M9799_RS16455	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
M9799_RS16455	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
M9799_RS16460	COG1802	Transcriptional regulator
M9799_RS16470	COG0583	DNA-binding transcription factor activity
M9799_RS16480	COG2072	flavoprotein involved in K transport
M9799_RS16485	COG0601	transmembrane transport
M9799_RS16490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M9799_RS16500	COG4608	Belongs to the ABC transporter superfamily
M9799_RS16505	COG0747	negative chemotaxis
M9799_RS16530	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M9799_RS16540	COG2878	Part of a membrane complex involved in electron transport
M9799_RS16550	COG2171	N-acyltransferase activity
M9799_RS16560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
M9799_RS16565	COG2890	protein-(glutamine-N5) methyltransferase activity
M9799_RS16570	COG0488	(ABC) transporter
M9799_RS16575	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS16580	COG0183	Belongs to the thiolase family
M9799_RS16585	COG3243	poly(R)-hydroxyalkanoic acid synthase
M9799_RS16610	COG2816	NAD+ diphosphatase activity
M9799_RS16630	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
M9799_RS16640	COG1196	nuclear chromosome segregation
M9799_RS16645	COG1742	UPF0060 membrane protein
M9799_RS16655	COG4181	ATPase activity
M9799_RS16670	COG0626	cystathionine gamma-synthase activity
M9799_RS16680	COG0659	secondary active sulfate transmembrane transporter activity
M9799_RS16695	COG1054	Belongs to the UPF0176 family
M9799_RS16700	COG0583	DNA-binding transcription factor activity
M9799_RS16705	COG1233	COG1233 Phytoene dehydrogenase and related
M9799_RS16715	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M9799_RS16720	COG1902	pentaerythritol trinitrate reductase activity
M9799_RS16735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
M9799_RS16755	COG1845	cytochrome c oxidase, subunit III
M9799_RS16760	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M9799_RS16775	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
M9799_RS16780	COG0109	protoheme IX farnesyltransferase activity
M9799_RS16805	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
M9799_RS16815	COG0795	lipopolysaccharide-transporting ATPase activity
M9799_RS16825	COG0583	DNA-binding transcription factor activity
M9799_RS16830	COG0436	Aminotransferase
M9799_RS16855	COG0424	maF-like protein
M9799_RS16860	COG1115	amino acid carrier protein
M9799_RS16875	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS16915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M9799_RS16930	COG0514	ATP-dependent DNA helicase (RecQ)
M9799_RS16940	COG0583	DNA-binding transcription factor activity
M9799_RS16950	COG0028	Belongs to the TPP enzyme family
M9799_RS16975	COG2916	Histone family protein nucleoid-structuring protein H-NS
M9799_RS16985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M9799_RS17030	COG1280	lysine exporter protein (LysE YggA)
M9799_RS17065	COG2188	Transcriptional regulator
M9799_RS17075	COG4948	Mandelate Racemase Muconate Lactonizing
M9799_RS17080	COG2707	UPF0756 membrane protein
M9799_RS17095	COG3040	lipid binding
M9799_RS17135	COG0625	glutathione transferase activity
M9799_RS17145	COG0840	transmembrane signaling receptor activity
M9799_RS17170	COG3665	Urea carboxylase-associated protein
M9799_RS17235	COG0583	DNA-binding transcription factor activity
M9799_RS17260	COG1192	Involved in chromosome partitioning
M9799_RS17315	COG3701	Conjugal transfer protein
M9799_RS17320	COG3451	type IV secretory pathway VirB4
M9799_RS17325	COG5268	conjugation
M9799_RS17330	COG3838	Conjugal transfer protein Trbc
M9799_RS17335	COG4962	Type ii secretion system protein e
M9799_RS17345	COG0656	L-ascorbic acid biosynthetic process
M9799_RS17350	COG2814	Major facilitator Superfamily
M9799_RS17355	COG0583	DNA-binding transcription factor activity
M9799_RS17405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M9799_RS17410	COG0800	Aldolase
M9799_RS17420	COG4221	oxidoreductase activity
M9799_RS17425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS17430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
M9799_RS17435	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
M9799_RS17440	COG3265	gluconokinase activity
M9799_RS17445	COG1609	Transcriptional regulator
M9799_RS17460	COG0563	adenylate kinase activity
M9799_RS17475	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS17485	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS17495	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS17500	COG0583	DNA-binding transcription factor activity
M9799_RS17515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M9799_RS17515	COG2169	Transcriptional regulator
M9799_RS17530	COG1120	ATPase activity
M9799_RS17535	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M9799_RS17565	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
M9799_RS17580	COG2205	protein histidine kinase activity
M9799_RS17600	COG1335	isochorismatase
M9799_RS17605	COG4993	Dehydrogenase
M9799_RS17615	COG0583	DNA-binding transcription factor activity
M9799_RS17650	COG0840	transmembrane signaling receptor activity
M9799_RS17680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS17685	COG1024	Enoyl-CoA hydratase
M9799_RS17690	COG1960	acyl-CoA dehydrogenase activity
M9799_RS17695	COG1960	acyl-CoA dehydrogenase activity
M9799_RS17700	COG0183	Belongs to the thiolase family
M9799_RS17705	COG1250	3-hydroxyacyl-CoA dehydrogenase
M9799_RS17705	COG1024	Enoyl-CoA hydratase
M9799_RS17710	COG0583	DNA-binding transcription factor activity
M9799_RS17720	COG2814	Major facilitator Superfamily
M9799_RS17725	COG1846	Transcriptional regulator
M9799_RS17735	COG1566	PFAM secretion protein HlyD family protein
M9799_RS17740	COG2814	Major facilitator Superfamily
M9799_RS17765	COG0657	acetylesterase activity
M9799_RS17810	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M9799_RS17820	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS17825	COG2226	methyltransferase
M9799_RS17855	COG2814	Major facilitator Superfamily
M9799_RS17880	COG0778	Nitroreductase
M9799_RS17890	COG0277	FAD linked oxidase domain protein
M9799_RS17905	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS17925	COG0765	amino acid transport
M9799_RS17930	COG0765	amino acid transport
M9799_RS17935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M9799_RS17945	COG1116	anion transmembrane transporter activity
M9799_RS17950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M9799_RS17960	COG0154	amidase activity
M9799_RS17985	COG0419	ATPase involved in DNA repair
M9799_RS17990	COG0420	3'-5' exonuclease activity
M9799_RS18000	COG2153	protein acetylation
M9799_RS18005	COG0697	spore germination
M9799_RS18025	COG2076	Multidrug Resistance protein
M9799_RS18030	COG0583	DNA-binding transcription factor activity
M9799_RS18035	COG2080	2 iron, 2 sulfur cluster binding
M9799_RS18040	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
M9799_RS18045	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M9799_RS18055	COG2032	superoxide dismutase activity
M9799_RS18065	COG4221	oxidoreductase activity
M9799_RS18095	COG2194	sulfuric ester hydrolase activity
M9799_RS18100	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
M9799_RS18105	COG0642	Histidine kinase
M9799_RS18115	COG2094	Belongs to the DNA glycosylase MPG family
M9799_RS18120	COG0492	ferredoxin-NADP+ reductase activity
M9799_RS18130	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9799_RS18130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M9799_RS18150	COG0587	DNA-directed DNA polymerase activity
M9799_RS18175	COG0583	DNA-binding transcription factor activity
M9799_RS18190	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
M9799_RS18200	COG0724	RNA recognition motif
M9799_RS18210	COG0583	DNA-binding transcription factor activity
M9799_RS18220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M9799_RS18250	COG0583	DNA-binding transcription factor activity
M9799_RS18290	COG3712	iron ion homeostasis
M9799_RS18310	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS18360	COG0477	Major facilitator Superfamily
M9799_RS18380	COG3210	domain, Protein
M9799_RS18385	COG2831	hemolysin activation secretion protein
M9799_RS18390	COG1522	sequence-specific DNA binding
M9799_RS18395	COG2423	ornithine cyclodeaminase activity
M9799_RS18420	COG0789	Transcriptional regulator
M9799_RS18430	COG0243	molybdopterin cofactor binding
M9799_RS18440	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M9799_RS18455	COG2200	EAL domain
M9799_RS18465	COG1201	RNA secondary structure unwinding
M9799_RS18470	COG1793	dna ligase
M9799_RS18475	COG1793	dna ligase
M9799_RS18475	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
M9799_RS18480	COG3550	peptidyl-serine autophosphorylation
M9799_RS18485	COG2706	6-phosphogluconolactonase activity
M9799_RS18490	COG1064	alcohol dehydrogenase
M9799_RS18495	COG1297	OPT oligopeptide transporter protein
M9799_RS18520	COG0596	Alpha beta hydrolase
M9799_RS18530	COG5380	lipid catabolic process
M9799_RS18535	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
M9799_RS18540	COG1414	Transcriptional regulator
M9799_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS18570	COG1349	DNA-binding transcription factor activity
M9799_RS18580	COG3395	kinase activity
M9799_RS18585	COG0235	Class ii aldolase
M9799_RS18590	COG0405	Gamma-glutamyltransferase
M9799_RS18595	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
M9799_RS18610	COG1609	Transcriptional regulator
M9799_RS18615	COG2326	polyphosphate kinase activity
M9799_RS18620	COG3227	Zinc metalloprotease (Elastase)
M9799_RS18640	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS18645	COG1960	acyl-CoA dehydrogenase activity
M9799_RS18655	COG1335	isochorismatase
M9799_RS18690	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS18715	COG1960	acyl-CoA dehydrogenase activity
M9799_RS18720	COG0318	PFAM AMP-dependent synthetase and ligase
M9799_RS18735	COG1960	acyl-CoA dehydrogenase activity
M9799_RS18740	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS18755	COG0583	DNA-binding transcription factor activity
M9799_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
M9799_RS18845	COG0583	DNA-binding transcription factor activity
M9799_RS18850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M9799_RS18860	COG0667	Aldo Keto reductase
M9799_RS18870	COG0154	amidase activity
M9799_RS18875	COG0693	protein deglycase activity
M9799_RS18880	COG1971	Probably functions as a manganese efflux pump
M9799_RS18885	COG0028	Belongs to the TPP enzyme family
M9799_RS18890	COG1522	sequence-specific DNA binding
M9799_RS18935	COG3550	peptidyl-serine autophosphorylation
M9799_RS18965	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
M9799_RS18990	COG4774	siderophore transport
M9799_RS19010	COG4221	oxidoreductase activity
M9799_RS19030	COG0583	DNA-binding transcription factor activity
M9799_RS19035	COG0823	Involved in the tonB-independent uptake of proteins
M9799_RS19035	COG1506	peptidase
M9799_RS19035	COG4946	Tricorn protease homolog
M9799_RS19060	COG2200	EAL domain
M9799_RS19075	COG0840	transmembrane signaling receptor activity
M9799_RS19085	COG0840	transmembrane signaling receptor activity
M9799_RS19125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M9799_RS19130	COG0069	glutamate synthase activity
M9799_RS19145	COG0583	DNA-binding transcription factor activity
M9799_RS19160	COG1335	isochorismatase
M9799_RS19185	COG0583	DNA-binding transcription factor activity
M9799_RS19190	COG0277	FAD linked oxidase domain protein
M9799_RS19190	COG0247	lactate metabolic process
M9799_RS19200	COG3119	arylsulfatase activity
M9799_RS19205	COG5002	protein histidine kinase activity
M9799_RS19210	COG1522	sequence-specific DNA binding
M9799_RS19215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M9799_RS19250	COG0235	Class ii aldolase
M9799_RS19260	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS19270	COG0784	Response regulator, receiver
M9799_RS19270	COG4191	Histidine kinase
M9799_RS19290	COG0529	Catalyzes the synthesis of activated sulfate
M9799_RS19295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M9799_RS19310	COG0457	Tetratricopeptide repeat
M9799_RS19325	COG0156	8-amino-7-oxononanoate synthase activity
M9799_RS19330	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
M9799_RS19335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
M9799_RS19340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
M9799_RS19370	COG0583	DNA-binding transcription factor activity
M9799_RS19380	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS19385	COG0626	cystathionine gamma-synthase activity
M9799_RS19435	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS19440	COG0583	DNA-binding transcription factor activity
M9799_RS19455	COG1053	succinate dehydrogenase
M9799_RS19465	COG2951	lytic endotransglycosylase activity
M9799_RS19475	COG4221	oxidoreductase activity
M9799_RS19480	COG2203	Gaf domain
M9799_RS19480	COG3706	GGDEF domain
M9799_RS19480	COG4251	negative regulation of phosphorylation
M9799_RS19480	COG5001	Diguanylate cyclase
M9799_RS19520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M9799_RS19535	COG3685	Protein conserved in bacteria
M9799_RS19545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M9799_RS19565	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS19580	COG1024	Enoyl-CoA hydratase
M9799_RS19595	COG0583	DNA-binding transcription factor activity
M9799_RS19615	COG3181	Tripartite tricarboxylate transporter family receptor
M9799_RS19630	COG1960	acyl-CoA dehydrogenase activity
M9799_RS19640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
M9799_RS19655	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M9799_RS19670	COG0514	ATP-dependent DNA helicase (RecQ)
M9799_RS19675	COG0583	DNA-binding transcription factor activity
M9799_RS19710	COG2916	Histone family protein nucleoid-structuring protein H-NS
M9799_RS19720	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
M9799_RS19765	COG1280	lysine exporter protein (LysE YggA)
M9799_RS19800	COG2188	Transcriptional regulator
M9799_RS19810	COG4948	Mandelate Racemase Muconate Lactonizing
M9799_RS19830	COG3040	lipid binding
M9799_RS19880	COG0840	transmembrane signaling receptor activity
M9799_RS19940	COG4962	Type ii secretion system protein e
M9799_RS19945	COG3838	Conjugal transfer protein Trbc
M9799_RS19955	COG3451	type IV secretory pathway VirB4
M9799_RS20005	COG2916	Histone family protein nucleoid-structuring protein H-NS
M9799_RS20015	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
M9799_RS20020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M9799_RS20035	COG0431	NADPH-dependent FMN reductase
M9799_RS20040	COG1393	Belongs to the ArsC family
M9799_RS20080	COG1715	Restriction endonuclease
M9799_RS20130	COG0789	Transcriptional regulator
M9799_RS20140	COG5002	protein histidine kinase activity
M9799_RS20235	COG2826	transposase and inactivated derivatives, IS30 family
M9799_RS20260	COG0789	Transcriptional regulator
M9799_RS20285	COG2205	protein histidine kinase activity
M9799_RS20335	COG4959	Type IV secretory pathway protease TraF
M9799_RS20380	COG4962	Type ii secretion system protein e
M9799_RS20385	COG3838	Conjugal transfer protein Trbc
M9799_RS20395	COG3451	type IV secretory pathway VirB4
M9799_RS20420	COG3701	Conjugal transfer protein
M9799_RS20445	COG2916	Histone family protein nucleoid-structuring protein H-NS
M9799_RS20455	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
M9799_RS20460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M9799_RS20480	COG1393	Belongs to the ArsC family
M9799_RS20520	COG1715	Restriction endonuclease