locus-tag	class	description
G7045_RS00005	ENOG4105DWV	Homoserine O-trans-acetylase
G7045_RS00010	ENOG4105DWV	Homoserine O-trans-acetylase
G7045_RS00025	ENOG4108KK1	membrane protein AbrB duplication
G7045_RS00030	ENOG4107QMH	DNA methylase
G7045_RS00045	ENOG4105E5G	Alpha beta hydrolase fold
G7045_RS00070	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
G7045_RS00075	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
G7045_RS00080	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
G7045_RS00090	ENOG4105DVT	helicase
G7045_RS00095	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
G7045_RS00100	ENOG4105DVT	helicase
G7045_RS00105	ENOG4108RPX	mosc domain containing protein
G7045_RS00110	ENOG4108VWS	Yaeq family
G7045_RS00115	ENOG4107QTF	adenylosuccinate lyase
G7045_RS00120	ENOG4108U78	Glutathione S-transferase
G7045_RS00145	ENOG4105BZU	Histidine kinase
G7045_RS00150	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G7045_RS00165	ENOG4105VIE	preprotein translocase, subunit YajC
G7045_RS00170	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G7045_RS00175	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
G7045_RS00185	ENOG4105C79	DNA protecting protein DprA
G7045_RS00195	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
G7045_RS00200	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
G7045_RS00205	ENOG4105BZA	Phosphoglycerate kinase
G7045_RS00210	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
G7045_RS00215	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS00225	ENOG4107RDB	Major Facilitator
G7045_RS00235	ENOG4108004	Modulates RecA activity (By similarity)
G7045_RS00240	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
G7045_RS00255	ENOG4105DHQ	Histidine kinase
G7045_RS00265	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
G7045_RS00275	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7045_RS00280	ENOG4107R3N	Filamentation induced by cAMP protein fic
G7045_RS00290	ENOG4105CYM	Glutathione S-transferase
G7045_RS00295	ENOG4105CK2	sodium dicarboxylate symporter
G7045_RS00305	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
G7045_RS00310	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
G7045_RS00315	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
G7045_RS00325	ENOG4108UW8	fha domain-containing protein
G7045_RS00335	ENOG4107RAQ	aminopeptidase
G7045_RS00340	ENOG4105CA9	Pyruvate kinase
G7045_RS00345	ENOG4105D2N	Aldolase
G7045_RS00350	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7045_RS00355	ENOG4105W8H	transhydrogenase (subunit alpha
G7045_RS00360	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
G7045_RS00365	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS00370	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
G7045_RS00380	ENOG4105D3Q	Sugar transferase
G7045_RS00400	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
G7045_RS00420	ENOG4105CAQ	asparagine synthetase
G7045_RS00440	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
G7045_RS00445	ENOG4105CB5	ATP-dependent DNA helicase recG
G7045_RS00460	ENOG4105J5G	Transferase hexapeptide repeat containing protein
G7045_RS00465	ENOG4107R5Z	Oxidoreductase domain protein
G7045_RS00470	ENOG4107QQG	Dehydrogenase
G7045_RS00480	ENOG4107QUT	magnesium and cobalt transport protein CorA
G7045_RS00495	ENOG41072GX	Peptidase M22 Glycoprotease
G7045_RS00500	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
G7045_RS00520	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7045_RS00525	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
G7045_RS00530	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
G7045_RS00535	ENOG4105K63	Thioredoxin
G7045_RS00540	ENOG4105C8V	SAICAR synthetase
G7045_RS00545	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
G7045_RS00550	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
G7045_RS00555	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
G7045_RS00560	ENOG41090R7	Ferric uptake
G7045_RS00565	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
G7045_RS00570	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
G7045_RS00580	ENOG4105SG9	biopolymer transport protein, ExbD
G7045_RS00585	ENOG4105C8T	Leucyl-tRNA synthetase
G7045_RS00600	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
G7045_RS00605	ENOG4105C1A	potassium transporter peripheral membrane
G7045_RS00610	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
G7045_RS00620	ENOG4105DFH	Transport of potassium into the cell (By similarity)
G7045_RS00625	ENOG4105DKK	Benzoate
G7045_RS00630	ENOG4105D7Z	glutathione synthase
G7045_RS00660	ENOG4108Z6Z	Transcriptional regulator
G7045_RS00665	ENOG4105C1G	acyl-Coa dehydrogenase
G7045_RS00670	ENOG41077A9	carbonic anhydrase
G7045_RS00675	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
G7045_RS00680	ENOG4105CHU	acetyl-coa acetyltransferase
G7045_RS00685	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS00705	ENOG4105CSR	polyphosphate kinase 2
G7045_RS00715	ENOG4105K5B	UPF0225 protein
G7045_RS00720	ENOG4105DEF	Extracellular solute-binding protein, family 5
G7045_RS00730	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
G7045_RS00745	ENOG4107QX3	carboxylase
G7045_RS00750	ENOG41060WC	Enoyl-CoA hydratase
G7045_RS00770	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
G7045_RS00795	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS00800	ENOG4105BZU	Histidine kinase
G7045_RS00810	ENOG4108IV0	ABC, transporter
G7045_RS00825	ENOG4105C32	Amino acid ABC transporter (Permease)
G7045_RS00830	ENOG4105C0Z	ABC transporter
G7045_RS00845	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7045_RS00850	ENOG4105C0P	Mg chelatase subunit ChlI
G7045_RS00855	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G7045_RS00860	ENOG41082RQ	UPF0102 protein
G7045_RS00865	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
G7045_RS00870	ENOG4105W4M	Transport-associated protein
G7045_RS00875	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G7045_RS00880	ENOG4105CZX	twitching motility protein
G7045_RS00885	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7045_RS00890	ENOG4105CZX	twitching motility protein
G7045_RS00895	ENOG4105DFA	alanine racemase domain protein
G7045_RS00925	ENOG4105CQB	FAD linked oxidase domain protein
G7045_RS00935	ENOG4105BZU	Histidine kinase
G7045_RS00945	ENOG4105BZU	Histidine kinase
G7045_RS00950	ENOG4105WH1	Two component transcriptional regulator luxr family
G7045_RS00970	ENOG4105DQQ	Major facilitator superfamily MFS_1
G7045_RS00975	ENOG4105CRU	nitrate reductase, alpha subunit
G7045_RS00980	ENOG4108IUE	nitrate reductase beta subunit
G7045_RS00985	ENOG4105R3A	Nitrate reductase
G7045_RS00990	ENOG4105D0D	Nitrate reductase 2, gamma subunit
G7045_RS00995	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G7045_RS01000	ENOG4107B2H	carbonic anhydrase
G7045_RS01020	ENOG4105NSG	hemerythrin hhe cation binding domain protein
G7045_RS01040	ENOG4108I6A	alcohol dehydrogenase
G7045_RS01065	ENOG4108J2R	molybdopterin oxidoreductase
G7045_RS01110	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS01125	ENOG4105MIR	Phenylalanine 4-monooxygenase
G7045_RS01135	ENOG4107IFA	Lipase (EC 3.1.1.3)
G7045_RS01145	ENOG4108JU5	Magnesium and cobalt efflux protein
G7045_RS01150	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
G7045_RS01155	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
G7045_RS01165	ENOG4107R0V	Pyruvate dehydrogenase
G7045_RS01170	ENOG4105CPP	Dehydrogenase, E1 component
G7045_RS01175	ENOG4107QSN	dihydrolipoamide acetyltransferase
G7045_RS01180	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7045_RS01185	ENOG4107IFA	Lipase (EC 3.1.1.3)
G7045_RS01200	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
G7045_RS01205	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
G7045_RS01215	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
G7045_RS01240	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
G7045_RS01260	ENOG4105PDP	Short chain dehydrogenase
G7045_RS01270	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
G7045_RS01280	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
G7045_RS01290	ENOG4107QHF	type ii secretion system protein e
G7045_RS01295	ENOG4105D7Q	type ii secretion system
G7045_RS01300	ENOG4108VAU	general secretion pathway protein G
G7045_RS01340	ENOG4105GVR	general secretion pathway protein D
G7045_RS01365	ENOG4105EY8	ABC transporter
G7045_RS01375	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G7045_RS01390	ENOG4105CAS	nag kinase
G7045_RS01405	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
G7045_RS01410	ENOG4107YZX	Universal stress protein
G7045_RS01415	ENOG4107QWB	Ornithine cyclodeaminase
G7045_RS01420	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
G7045_RS01450	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
G7045_RS01455	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
G7045_RS01460	ENOG4105DX0	Hemolysin A
G7045_RS01465	ENOG4105SYT	Methylenetetrahydrofolate reductase
G7045_RS01475	ENOG4105D6S	protein involved in catabolism of external DNA
G7045_RS01480	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
G7045_RS01485	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
G7045_RS01490	ENOG4108UJD	30S ribosomal protein S9
G7045_RS01495	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
G7045_RS01500	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
G7045_RS01505	ENOG4105DR5	peptidase
G7045_RS01515	ENOG4105W3S	hemerythrin-like, metal-binding protein
G7045_RS01520	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
G7045_RS01530	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
G7045_RS01535	ENOG4108RXX	maleylacetoacetate isomerase
G7045_RS01540	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
G7045_RS01545	ENOG4107SC1	transglycosylase
G7045_RS01555	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
G7045_RS01565	ENOG4107QP8	phosphohexose isomerase
G7045_RS01570	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
G7045_RS01575	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
G7045_RS01585	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
G7045_RS01595	ENOG4105D1S	lipid A biosynthesis
G7045_RS01600	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
G7045_RS01610	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
G7045_RS01615	ENOG4105CRE	cytochrome C
G7045_RS01620	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
G7045_RS01630	ENOG4105XQ6	frataxin-like protein
G7045_RS01635	ENOG4108JQC	penicillin-binding protein 1A
G7045_RS01660	ENOG4105E4G	Type IV pilus
G7045_RS01670	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
G7045_RS01675	ENOG4105D49	3-dehydroquinate synthase
G7045_RS01680	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
G7045_RS01690	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
G7045_RS01695	ENOG4105C7B	Threonine dehydratase
G7045_RS01700	ENOG4108UKZ	OsmC family
G7045_RS01705	ENOG4108Z9W	Outer membrane porin
G7045_RS01715	ENOG4105CH2	amidohydrolase
G7045_RS01735	ENOG4105BZU	Histidine kinase
G7045_RS01740	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
G7045_RS01760	ENOG4105F7P	transcriptional regulator AsnC family
G7045_RS01775	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7045_RS01780	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
G7045_RS01790	ENOG4105M6F	mutator MutT protein
G7045_RS01795	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
G7045_RS01800	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
G7045_RS01805	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
G7045_RS01810	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
G7045_RS01820	ENOG4107QHF	type ii secretion system protein e
G7045_RS01845	ENOG4105EAH	synthase
G7045_RS01850	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
G7045_RS01855	ENOG4105K46	50S ribosomal protein l27
G7045_RS01860	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7045_RS01865	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
G7045_RS01870	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
G7045_RS01875	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
G7045_RS01880	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
G7045_RS01885	ENOG4105C37	(CBS) domain
G7045_RS01900	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
G7045_RS01905	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
G7045_RS01915	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
G7045_RS01920	ENOG4108IJ9	(ABC) transporter
G7045_RS01930	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
G7045_RS01935	ENOG4105BZ7	extracellular solute-binding protein family 1
G7045_RS01940	ENOG4108JQ1	Dehydrogenase
G7045_RS01975	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
G7045_RS01995	ENOG4105C9M	aspartyl-trna synthetase
G7045_RS02005	ENOG4105DZQ	phospholipase D Transphosphatidylase
G7045_RS02010	ENOG4105EUJ	GTP cyclohydrolase i
G7045_RS02025	ENOG410829K	Lysine exporter protein (Lyse ygga)
G7045_RS02030	ENOG4105DEF	Extracellular solute-binding protein, family 5
G7045_RS02035	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
G7045_RS02045	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
G7045_RS02050	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
G7045_RS02055	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
G7045_RS02060	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
G7045_RS02070	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
G7045_RS02075	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
G7045_RS02085	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
G7045_RS02095	ENOG4105CEN	a g-specific adenine glycosylase
G7045_RS02100	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
G7045_RS02105	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
G7045_RS02110	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
G7045_RS02115	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
G7045_RS02155	ENOG4108IGT	Dipeptidase
G7045_RS02255	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7045_RS02260	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
G7045_RS02265	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
G7045_RS02270	ENOG4105DSJ	YicC domain protein
G7045_RS02290	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
G7045_RS02295	ENOG4105CSA	Coproporphyrinogen iii oxidase
G7045_RS02320	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
G7045_RS02325	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS02330	ENOG4105BZU	Histidine kinase
G7045_RS02335	ENOG4108PYU	two-component system response regulator
G7045_RS02345	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
G7045_RS02355	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
G7045_RS02360	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS02370	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7045_RS02375	ENOG4108IUZ	ABC transporter
G7045_RS02385	ENOG4107QN1	sodium solute
G7045_RS02405	ENOG4105C75	arginyL-tRNA synthetase
G7045_RS02415	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS02435	ENOG4105DDQ	anthranilate synthase
G7045_RS02440	ENOG4107QYG	anthranilate phosphoribosyltransferase
G7045_RS02445	ENOG4105DK0	Indole-3-glycerol phosphate synthase
G7045_RS02450	ENOG4105BZU	Histidine kinase
G7045_RS02455	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
G7045_RS02460	ENOG4107QN1	sodium solute
G7045_RS02465	ENOG41062QD	Membrane
G7045_RS02470	ENOG4105CSH	Transporter
G7045_RS02475	ENOG4108Z9W	Outer membrane porin
G7045_RS02480	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
G7045_RS02485	ENOG4105CVR	type I restriction-modification system
G7045_RS02495	ENOG4105EKX	Restriction modification system DNA (Specificity
G7045_RS02500	ENOG4105DZR	Type I site-specific deoxyribonuclease
G7045_RS02505	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
G7045_RS02510	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
G7045_RS02515	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G7045_RS02535	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7045_RS02550	ENOG4105BZU	Histidine kinase
G7045_RS02570	ENOG4106H78	methyltransferase
G7045_RS02575	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
G7045_RS02585	ENOG4105D06	uba thif-type nad fad binding protein
G7045_RS02590	ENOG4105CN1	protease
G7045_RS02595	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
G7045_RS02600	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
G7045_RS02610	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
G7045_RS02615	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
G7045_RS02655	ENOG4105C6K	Malic enzyme
G7045_RS02660	ENOG4105TMB	Formate nitrite transporter
G7045_RS02665	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G7045_RS02675	ENOG4105BZU	Histidine kinase
G7045_RS02700	ENOG4108IFG	nitrite reductase, (NAD(P)H)
G7045_RS02705	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
G7045_RS02710	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
G7045_RS02715	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G7045_RS02720	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
G7045_RS02725	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
G7045_RS02735	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
G7045_RS02740	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
G7045_RS02745	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G7045_RS02755	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
G7045_RS02760	ENOG4105DDW	LysR family Transcriptional regulator
G7045_RS02765	ENOG4105CY0	Metallo-Beta-Lactamase
G7045_RS02770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
G7045_RS02775	ENOG4105CFG	Acts as a chaperone (By similarity)
G7045_RS02780	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7045_RS02785	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
G7045_RS02795	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
G7045_RS02800	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
G7045_RS02805	ENOG4105CDU	Replicative dna helicase
G7045_RS02810	ENOG4108IAB	Phoh family
G7045_RS02815	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7045_RS02825	ENOG4105CHM	Aminotransferase
G7045_RS02830	ENOG4105D6E	homoserine dehydrogenase
G7045_RS02835	ENOG4105D98	threonine synthase
G7045_RS02840	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
G7045_RS02845	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
G7045_RS02865	ENOG4108ZAF	Molybdopterin
G7045_RS02875	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
G7045_RS02885	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
G7045_RS02900	ENOG4105C08	Histidine kinase
G7045_RS02905	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
G7045_RS02910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7045_RS02920	ENOG4107RGH	Aldehyde dehydrogenase
G7045_RS02930	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
G7045_RS02935	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
G7045_RS02940	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
G7045_RS02950	ENOG4108UNV	SUF system FeS assembly protein, NifU family
G7045_RS02955	ENOG4105C9B	Cysteine desulfurase
G7045_RS02965	ENOG4105C3K	feS assembly ATPase SufC
G7045_RS02975	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
G7045_RS02980	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
G7045_RS02990	ENOG4105CP7	Triose-phosphate isomerase
G7045_RS02995	ENOG4107EJC	Preprotein translocase subunit SecG
G7045_RS03005	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G7045_RS03010	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7045_RS03015	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G7045_RS03020	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7045_RS03030	ENOG4107QIZ	NADH dehydrogenase
G7045_RS03035	ENOG4108IEH	NADH dehydrogenase subunit g
G7045_RS03040	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
G7045_RS03045	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7045_RS03050	ENOG4105DF2	NADH dehydrogenase subunit j
G7045_RS03055	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7045_RS03065	ENOG4105C8S	subunit m
G7045_RS03070	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
G7045_RS03095	ENOG4105E0K	tonB-dependent siderophore receptor
G7045_RS03115	ENOG4105E0K	tonB-dependent siderophore receptor
G7045_RS03120	ENOG4105C0Z	ABC transporter
G7045_RS03125	ENOG4108IV0	ABC, transporter
G7045_RS03135	ENOG4105C32	Amino acid ABC transporter (Permease)
G7045_RS03155	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
G7045_RS03160	ENOG4105D82	Glutamate dehydrogenase
G7045_RS03165	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
G7045_RS03170	ENOG4105DQR	SNARE associated Golgi
G7045_RS03175	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
G7045_RS03180	ENOG4105K8N	protein family UPF0079, ATPase
G7045_RS03185	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
G7045_RS03190	ENOG4105BZU	Histidine kinase
G7045_RS03200	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G7045_RS03205	ENOG4105D58	Diguanylate phosphodiesterase
G7045_RS03210	ENOG4105D58	Diguanylate phosphodiesterase
G7045_RS03215	ENOG4105ED9	Protein of unknown function (DUF455)
G7045_RS03220	ENOG4108Z0R	Transferase
G7045_RS03225	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
G7045_RS03230	ENOG4105E89	ABC transporter
G7045_RS03235	ENOG4105DSP	amino acid AbC transporter
G7045_RS03245	ENOG4108JEH	abc transporter atp-binding protein
G7045_RS03250	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
G7045_RS03255	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
G7045_RS03260	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
G7045_RS03265	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
G7045_RS03270	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
G7045_RS03275	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
G7045_RS03310	ENOG4108781	Fimbrial protein
G7045_RS03330	ENOG4108RG0	uracil-dna glycosylase
G7045_RS03335	ENOG4105D1H	recombination factor protein RarA
G7045_RS03340	ENOG4105C32	Amino acid ABC transporter (Permease)
G7045_RS03345	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G7045_RS03350	ENOG4105C0Z	ABC transporter
G7045_RS03355	ENOG4108IV0	ABC, transporter
G7045_RS03365	ENOG4107GRR	phosphate transport regulator
G7045_RS03370	ENOG4107QXV	Phosphate transporter
G7045_RS03375	ENOG4105EYA	deoxyribonuclease
G7045_RS03380	ENOG4105I7M	spermidine synthase
G7045_RS03385	ENOG4107QHF	type ii secretion system protein e
G7045_RS03410	ENOG4105BZU	Histidine kinase
G7045_RS03415	ENOG4108IPJ	Membrane
G7045_RS03420	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
G7045_RS03425	ENOG4105EAM	Na Pi-cotransporter
G7045_RS03430	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
G7045_RS03440	ENOG4105DTN	riboflavin biosynthesis protein ribF
G7045_RS03445	ENOG4105FFC	UPF0187 protein
G7045_RS03450	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7045_RS03455	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
G7045_RS03465	ENOG4105W0E	50S ribosomal protein L33
G7045_RS03470	ENOG4105KDC	50s ribosomal protein l28
G7045_RS03475	ENOG4105C3M	thioredoxin reductase
G7045_RS03480	ENOG4105CNU	cell division protein FtsK
G7045_RS03485	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
G7045_RS03490	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
G7045_RS03515	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
G7045_RS03520	ENOG4105BZU	Histidine kinase
G7045_RS03525	ENOG4105BZU	Histidine kinase
G7045_RS03530	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G7045_RS03535	ENOG4105ECY	inositol monophosphatase
G7045_RS03545	ENOG4105D7W	serine acetyltransferase
G7045_RS03550	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
G7045_RS03560	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
G7045_RS03570	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
G7045_RS03575	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
G7045_RS03585	ENOG4107QN1	sodium solute
G7045_RS03590	ENOG4108V1T	peptidylprolyl cis-trans isomerase
G7045_RS03600	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
G7045_RS03615	ENOG4108Z6Z	Transcriptional regulator
G7045_RS03630	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7045_RS03640	ENOG4107RUE	extracellular solute-binding protein family 1
G7045_RS03645	ENOG4105BZU	Histidine kinase
G7045_RS03650	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS03655	ENOG4105C8J	)-transporter
G7045_RS03660	ENOG4105DGI	Alkaline phosphatase
G7045_RS03670	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
G7045_RS03675	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G7045_RS03680	ENOG4108K5P	(LipO)protein
G7045_RS03685	ENOG4105C34	Pseudouridine synthase
G7045_RS03690	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
G7045_RS03695	ENOG4105FE9	pseudouridine synthase
G7045_RS03700	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
G7045_RS03705	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
G7045_RS03720	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
G7045_RS03725	ENOG4105CUT	histidyl-tRNA synthetase
G7045_RS03740	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
G7045_RS03745	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
G7045_RS03750	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
G7045_RS03755	ENOG4107QJR	hflk protein
G7045_RS03760	ENOG4105EPW	hflc protein
G7045_RS03770	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
G7045_RS03775	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
G7045_RS03780	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
G7045_RS03810	ENOG4105I08	Pseudouridine synthase
G7045_RS03850	ENOG4105CUX	Signal transduction histidine kinase
G7045_RS03855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7045_RS03860	ENOG4108VDT	Glycosyl transferase family protein
G7045_RS03865	ENOG4105CGK	Exodeoxyribonuclease III
G7045_RS03875	ENOG4108VYJ	response regulator receiver protein
G7045_RS03880	ENOG4107QYX	exodeoxyribonuclease v alpha
G7045_RS03890	ENOG4105XEA	Tetr family transcriptional regulator
G7045_RS03895	ENOG4105D0S	secretion protein (HlyD
G7045_RS03900	ENOG4105CJ1	ABC, transporter
G7045_RS03905	ENOG4107QWP	ABC-2 type transporter
G7045_RS03910	ENOG4107QWP	ABC-2 type transporter
G7045_RS03925	ENOG4105CJ1	ABC, transporter
G7045_RS03955	ENOG4107QKA	exodeoxyribonuclease V beta
G7045_RS03965	ENOG4107R3N	Filamentation induced by cAMP protein fic
G7045_RS03970	ENOG4105DSY	exodeoxyribonuclease V, gamma
G7045_RS04000	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS04020	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
G7045_RS04025	ENOG4105CQB	FAD linked oxidase domain protein
G7045_RS04035	ENOG4107S2Z	UPF0761 membrane protein
G7045_RS04050	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
G7045_RS04055	ENOG4107T31	5'-nucleotidase
G7045_RS04060	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
G7045_RS04065	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
G7045_RS04070	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
G7045_RS04095	ENOG4105EKQ	RNA-directed DNA polymerase
G7045_RS04100	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
G7045_RS04105	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
G7045_RS04110	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G7045_RS04120	ENOG4105CE9	30S ribosomal protein S2
G7045_RS04125	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
G7045_RS04130	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
G7045_RS04135	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
G7045_RS04140	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
G7045_RS04145	ENOG4105KNE	Phosphatidate cytidylyltransferase
G7045_RS04150	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
G7045_RS04155	ENOG4105DZP	Membrane-associated zinc metalloprotease
G7045_RS04160	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7045_RS04170	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7045_RS04175	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
G7045_RS04180	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7045_RS04185	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7045_RS04190	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7045_RS04205	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
G7045_RS04210	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
G7045_RS04220	ENOG4105HBR	Rna-binding protein
G7045_RS04225	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
G7045_RS04230	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7045_RS04235	ENOG4105EEI	dihydropteroate synthase
G7045_RS04240	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
G7045_RS04250	ENOG4105BZU	Histidine kinase
G7045_RS04270	ENOG4105CHR	reductase
G7045_RS04285	ENOG4105BZM	domain protein
G7045_RS04300	ENOG4105CX6	glutaminyL-tRNA synthetase
G7045_RS04310	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
G7045_RS04325	ENOG4108UQY	Iron-storage protein
G7045_RS04335	ENOG4108JU3	Alkyl hydroperoxide reductase
G7045_RS04370	ENOG4105HEE	Binding Domain protein
G7045_RS04375	ENOG4105EKT	)-iron permease
G7045_RS04395	ENOG4105D01	(LipO)protein
G7045_RS04400	ENOG4105EAC	phosphoserine phosphatase
G7045_RS04415	ENOG4108JA2	transcriptioN-repair coupling factor
G7045_RS04420	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
G7045_RS04425	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
G7045_RS04435	ENOG4105E0F	Histidine kinase
G7045_RS04440	ENOG4105DTR	rard protein
G7045_RS04445	ENOG4105BZJ	Electron transfer flavoprotein
G7045_RS04450	ENOG4105C10	Electron transfer flavoprotein
G7045_RS04455	ENOG4105CSU	acyl-Coa dehydrogenase
G7045_RS04460	ENOG4105EA8	2-Nitropropane dioxygenase
G7045_RS04470	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
G7045_RS04495	ENOG4105C8N	cysteinyl-tRNA synthetase
G7045_RS04505	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
G7045_RS04510	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS04515	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
G7045_RS04520	ENOG4105CFH	Aspartokinase
G7045_RS04535	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
G7045_RS04575	ENOG4105DTT	CRISPR-associated helicase, cas3
G7045_RS04580	ENOG4105VEJ	Heat shock protein
G7045_RS04585	ENOG4105DAN	ATP-dependent protease
G7045_RS04590	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
G7045_RS04600	ENOG4107S11	squalene-associated FAD-dependent desaturase
G7045_RS04605	ENOG4105FE1	phytoene synthase
G7045_RS04610	ENOG4105EJQ	L-serine dehydratase
G7045_RS04625	ENOG4105BZS	acriflavin resistance protein
G7045_RS04635	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
G7045_RS04640	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
G7045_RS04645	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
G7045_RS04680	ENOG4108VKG	metal-dependent hydrolase
G7045_RS04685	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
G7045_RS04705	ENOG4105G6Z	alkaline phosphatase
G7045_RS04710	ENOG4105W2Z	cytochrome C, class I
G7045_RS04720	ENOG4105C01	Dihydroxy-acid dehydratase
G7045_RS04730	ENOG4108UWD	Iron-storage protein
G7045_RS04735	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
G7045_RS04745	ENOG4107YZX	Universal stress protein
G7045_RS04750	ENOG4105C59	p-type ATPase
G7045_RS04760	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
G7045_RS04780	ENOG4105C58	cytochrome c oxidase accessory protein ccog
G7045_RS04790	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
G7045_RS04795	ENOG4105D4P	Coproporphyrinogen iii oxidase
G7045_RS04805	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
G7045_RS04810	ENOG4105BZU	Histidine kinase
G7045_RS04815	ENOG4105HF0	Membrane
G7045_RS04830	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G7045_RS04835	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G7045_RS04840	ENOG4108YZT	Adenosylcobinamide kinase
G7045_RS04845	ENOG4108HUF	Transporter
G7045_RS04850	ENOG4105EHG	Permease protein
G7045_RS04855	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
G7045_RS04865	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
G7045_RS04870	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
G7045_RS04875	ENOG4107QRP	cobalamin biosynthesis protein CobW
G7045_RS04880	ENOG4105CTK	cobaltochelatase, cobn subunit
G7045_RS04895	ENOG4105E0K	tonB-dependent siderophore receptor
G7045_RS04910	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
G7045_RS04915	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G7045_RS04925	ENOG4105BZU	Histidine kinase
G7045_RS04940	ENOG4108R99	pseudouridine synthase
G7045_RS04955	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
G7045_RS04960	ENOG4105HHA	aminodeoxychorismate lyase
G7045_RS04965	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
G7045_RS04970	ENOG4107QRG	dna polymerase iii
G7045_RS04980	ENOG4105F8V	Hydrolase, tatD family
G7045_RS04990	ENOG4105BZ1	(ABC) transporter
G7045_RS04995	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
G7045_RS05000	ENOG4105KCK	Peptidoglycan-associated lipoprotein
G7045_RS05010	ENOG4105CUZ	uba thif-type nad fad binding protein
G7045_RS05025	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
G7045_RS05030	ENOG4105C7S	Dehydrogenase
G7045_RS05035	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7045_RS05040	ENOG4105D6Z	AFG1 family ATPase
G7045_RS05050	ENOG4108ZF3	Phosphatase
G7045_RS05055	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
G7045_RS05070	ENOG4105D7A	ATP-binding protein
G7045_RS05075	ENOG4105CDY	transcriptional regulatory protein
G7045_RS05080	ENOG4105C12	Phosphoribosylglycinamide synthetase
G7045_RS05085	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
G7045_RS05090	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
G7045_RS05095	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
G7045_RS05100	ENOG4108Z03	MAF-like protein
G7045_RS05110	ENOG4105FAE	von Willebrand factor, type A
G7045_RS05115	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
G7045_RS05120	ENOG4105DSQ	Nitric oxide reductase
G7045_RS05125	ENOG4108VKQ	nitriC oxide reductase
G7045_RS05155	ENOG4108ZGY	Transcriptional regulator (AsnC family)
G7045_RS05160	ENOG4108UMR	transcriptional regulator AsnC family
G7045_RS05175	ENOG4105F64	nitrite reductase
G7045_RS05180	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
G7045_RS05185	ENOG4105C03	ribonuclease
G7045_RS05200	ENOG4105KUZ	arsenate reductase
G7045_RS05205	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
G7045_RS05220	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
G7045_RS05225	ENOG4105C28	cystathionine
G7045_RS05230	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
G7045_RS05270	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
G7045_RS05275	ENOG4105K63	Thioredoxin
G7045_RS05285	ENOG4105BZ8	glutamate synthase
G7045_RS05295	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
G7045_RS05305	ENOG4105S10	periplasmic binding protein
G7045_RS05310	ENOG4108I9K	permease protein
G7045_RS05315	ENOG4105E0A	ABC, transporter
G7045_RS05320	ENOG4108BSC	Methyltransferase
G7045_RS05335	ENOG4105E0C	molybdate abc transporter
G7045_RS05340	ENOG4107XWS	modD protein
G7045_RS05345	ENOG4105F4R	Transcriptional regulator mode
G7045_RS05370	ENOG4108V3W	Chemotaxis protein, CheW
G7045_RS05375	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS05380	ENOG4108Z9W	Outer membrane porin
G7045_RS05390	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
G7045_RS05395	ENOG4107QMP	dna polymerase iii subunits gamma and tau
G7045_RS05400	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
G7045_RS05405	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
G7045_RS05410	ENOG4105E9H	Lytic Murein transglycosylase
G7045_RS05415	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
G7045_RS05420	ENOG4105D1A	Methyltransferase
G7045_RS05425	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
G7045_RS05440	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
G7045_RS05445	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7045_RS05475	ENOG4105CXN	decarboxylase
G7045_RS05485	ENOG4105Z2P	Protein of unknown function (DUF465)
G7045_RS05510	ENOG4105WD1	Membrane
G7045_RS05525	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
G7045_RS05530	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
G7045_RS05535	ENOG4108ETH	Formylglycinamide ribotide synthetase
G7045_RS05540	ENOG4105CKW	Inner membrane protein yedI
G7045_RS05545	ENOG4108UXE	Protein tyrosine phosphatase
G7045_RS05560	ENOG4105D6J	arsenicaL-resistance protein
G7045_RS05565	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7045_RS05575	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
G7045_RS05580	ENOG4105DZ2	Transcriptional regulator
G7045_RS05590	ENOG4105CFP	Peptidase U32
G7045_RS05600	ENOG4108Z6B	deaminase
G7045_RS05605	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
G7045_RS05615	ENOG4105C26	Dehydrogenase
G7045_RS05625	ENOG4105C1G	acyl-Coa dehydrogenase
G7045_RS05635	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7045_RS05645	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
G7045_RS05650	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
G7045_RS05670	ENOG4105CAY	ferredoxin--nadp reductase
G7045_RS05675	ENOG4108Z4U	Ferredoxin
G7045_RS05690	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
G7045_RS05705	ENOG4107TSN	permease
G7045_RS05710	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
G7045_RS05715	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
G7045_RS05725	ENOG4105DJ4	phosphatidylserine decarboxylase
G7045_RS05730	ENOG4105W87	Cbs domain
G7045_RS05735	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G7045_RS05750	ENOG41081QV	Universal stress protein
G7045_RS05755	ENOG4105BZU	Histidine kinase
G7045_RS05775	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
G7045_RS05780	ENOG4105E66	phosphoriboisomerase A
G7045_RS05790	ENOG4105DGW	oligopeptidase A
G7045_RS05795	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
G7045_RS05800	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G7045_RS05805	ENOG4105BZU	Histidine kinase
G7045_RS05810	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
G7045_RS05815	ENOG4107QSN	dihydrolipoamide acetyltransferase
G7045_RS05820	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7045_RS05860	ENOG4107QHF	type ii secretion system protein e
G7045_RS05870	ENOG4107QN2	dihydrolipoyl dehydrogenase
G7045_RS05875	ENOG4106UX7	integral membrane protein
G7045_RS05880	ENOG4105K78	MarR family Transcriptional regulator
G7045_RS05895	ENOG4105K4H	Nlp p60 protein
G7045_RS05905	ENOG4105CTQ	phosphohexokinase
G7045_RS05910	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
G7045_RS05915	ENOG4105EY8	ABC transporter
G7045_RS05925	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7045_RS05930	ENOG4105EXC	Acyl-transferase
G7045_RS05970	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
G7045_RS05975	ENOG4108DMA	Nad-dependent epimerase dehydratase
G7045_RS05980	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G7045_RS05985	ENOG4105C1G	acyl-Coa dehydrogenase
G7045_RS05990	ENOG4105C26	Dehydrogenase
G7045_RS05995	ENOG4106NZI	LysR family Transcriptional regulator
G7045_RS06000	ENOG4105C85	amino acid
G7045_RS06010	ENOG4105C7F	AcnD-accessory protein PrpF
G7045_RS06015	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
G7045_RS06020	ENOG4108I0Z	Aconitate hydratase
G7045_RS06025	ENOG4105BZN	citrate synthase
G7045_RS06030	ENOG4105CFF	transcriptional regulator
G7045_RS06035	ENOG4105BZU	Histidine kinase
G7045_RS06040	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
G7045_RS06050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
G7045_RS06080	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
G7045_RS06090	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G7045_RS06095	ENOG4105CHU	acetyl-coa acetyltransferase
G7045_RS06100	ENOG4105CHR	reductase
G7045_RS06105	ENOG4105C5H	ABC transporter
G7045_RS06110	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
G7045_RS06115	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
G7045_RS06120	ENOG4105CZX	twitching motility protein
G7045_RS06125	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
G7045_RS06130	ENOG4105CHM	Aminotransferase
G7045_RS06135	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS06140	ENOG4108R3D	Electron transport complex
G7045_RS06150	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G7045_RS06175	ENOG4105ECI	YeeC-like protein
G7045_RS06180	ENOG4105F6A	helicase
G7045_RS06185	ENOG4105D85	methylase
G7045_RS06295	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
G7045_RS06300	ENOG4108UMI	ABC transporter, permease
G7045_RS06305	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G7045_RS06310	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
G7045_RS06315	ENOG4105HEI	LysR family (Transcriptional regulator
G7045_RS06320	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
G7045_RS06325	ENOG4108I5D	sulfate abc transporter
G7045_RS06340	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
G7045_RS06360	ENOG4105DHT	Metal Dependent Phosphohydrolase
G7045_RS06365	ENOG4108EKC	n-acetylglutamate synthase
G7045_RS06370	ENOG4105EXC	Acyl-transferase
G7045_RS06375	ENOG4105CQ7	ATP-dependent helicase
G7045_RS06395	ENOG4108IQE	Amp-dependent synthetase and ligase
G7045_RS06400	ENOG4105DRR	Transcriptional regulator, GntR family
G7045_RS06420	ENOG4105DJT	lAO AO transport system ATPase
G7045_RS06425	ENOG4107QX3	carboxylase
G7045_RS06445	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
G7045_RS06465	ENOG4105DFG	type I secretion outer membrane protein
G7045_RS06475	ENOG4105BZS	acriflavin resistance protein
G7045_RS06485	ENOG41082BM	Transcriptional regulator, arsr family
G7045_RS06490	ENOG4105CVR	type I restriction-modification system
G7045_RS06495	ENOG4108UK5	Transposase
G7045_RS06500	ENOG41062MS	nucleotidyltransferase substrate binding protein
G7045_RS06505	ENOG4105EKX	Restriction modification system DNA (Specificity
G7045_RS06510	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
G7045_RS06515	ENOG4105DZR	Type I site-specific deoxyribonuclease
G7045_RS06520	ENOG4108UYE	Lactoylglutathione lyase
G7045_RS06530	ENOG4105HEI	LysR family (Transcriptional regulator
G7045_RS06535	ENOG4105DS1	cytochrome b561
G7045_RS06540	ENOG4108YYC	ycei family
G7045_RS06545	ENOG4108YYC	ycei family
G7045_RS06550	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
G7045_RS06555	ENOG4105UGU	tonB-dependent Receptor
G7045_RS06565	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
G7045_RS06585	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
G7045_RS06600	ENOG4105BZU	Histidine kinase
G7045_RS06605	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
G7045_RS06610	ENOG4107QKV	phosphomannomutase
G7045_RS06615	ENOG4105BZU	Histidine kinase
G7045_RS06620	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
G7045_RS06640	ENOG4105E9K	Isocitrate dehydrogenase
G7045_RS06645	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
G7045_RS06650	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G7045_RS06665	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
G7045_RS06670	ENOG4105W49	UPF0434 protein
G7045_RS06675	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
G7045_RS06680	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
G7045_RS06695	ENOG4105HDK	L-asparaginase
G7045_RS06700	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
G7045_RS06705	ENOG4105C5I	Dehydrogenase
G7045_RS06720	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
G7045_RS06740	ENOG4107R11	Transcriptional regulator
G7045_RS06745	ENOG4105CHM	Aminotransferase
G7045_RS06755	ENOG4105D3G	Pseudouridine synthase
G7045_RS06760	ENOG410904N	short-chain dehydrogenase reductase
G7045_RS06765	ENOG4105CHU	acetyl-coa acetyltransferase
G7045_RS06780	ENOG4108XDN	Transcriptional regulator
G7045_RS06785	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
G7045_RS06790	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
G7045_RS06795	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
G7045_RS06800	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
G7045_RS06805	ENOG4105VJV	50s ribosomal protein L35
G7045_RS06810	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
G7045_RS06815	ENOG4105C22	threonyL-tRNA synthetase
G7045_RS06820	ENOG4108I9X	Isocitrate lyase
G7045_RS06830	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
G7045_RS06840	ENOG4108ESX	Receptor
G7045_RS06845	ENOG4107E2E	PKHD-type hydroxylase
G7045_RS06870	ENOG4105SG9	biopolymer transport protein, ExbD
G7045_RS06880	ENOG4105EE5	Membrane protein terC
G7045_RS06900	ENOG4107RZZ	dna polymerase iii epsilon subunit
G7045_RS06905	ENOG4108ZIT	Ferredoxin, 2FE-2S
G7045_RS06910	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
G7045_RS06925	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
G7045_RS06930	ENOG4105C3J	Cysteine desulfurase
G7045_RS06945	ENOG4105CGF	Aromatic amino acid aminotransferase
G7045_RS06950	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
G7045_RS06955	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
G7045_RS06960	ENOG4105C0B	DNA polymerase III (alpha subunit)
G7045_RS06980	ENOG4108R85	Short chain dehydrogenase
G7045_RS06985	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
G7045_RS07005	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7045_RS07015	ENOG4105C0F	tryptophanase EC 4.1.99.1
G7045_RS07025	ENOG4105C7J	ABC transporter, permease
G7045_RS07030	ENOG4105D5T	phosphonate abc transporter
G7045_RS07035	ENOG4108IQI	permease
G7045_RS07040	ENOG4105EW9	transcriptional regulator AsnC family
G7045_RS07045	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
G7045_RS07050	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
G7045_RS07055	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7045_RS07215	ENOG4105CI3	gtp-binding protein typa
G7045_RS07220	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
G7045_RS07225	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
G7045_RS07230	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
G7045_RS07235	ENOG4105CHV	Transcription elongation factor NusA
G7045_RS07240	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
G7045_RS07250	ENOG4108JQ5	ABC transporter
G7045_RS07255	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
G7045_RS07270	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
G7045_RS07285	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G7045_RS07295	ENOG4105ED1	spovr family
G7045_RS07300	ENOG4106AKX	UPF0229 protein
G7045_RS07305	ENOG4105CYN	Serine protein kinase
G7045_RS07310	ENOG4105CCT	upf0313 protein
G7045_RS07315	ENOG4105CP9	extracellular ligand-binding receptor
G7045_RS07320	ENOG4105C32	Amino acid ABC transporter (Permease)
G7045_RS07325	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
G7045_RS07330	ENOG4105C0Z	ABC transporter
G7045_RS07335	ENOG4108IV0	ABC, transporter
G7045_RS07340	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
G7045_RS07350	ENOG4105D0M	Protease HtpX homolog
G7045_RS07360	ENOG4105F8J	Adenylate Guanylate cyclase
G7045_RS07370	ENOG4105C2N	RNA methyltransferase TrmH family group 3
G7045_RS07375	ENOG4107QV7	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
G7045_RS07380	ENOG4108I0Y	(ABC) transporter
G7045_RS07385	ENOG4108UJV	acyl-CoA thioesterase i
G7045_RS07390	ENOG4105C28	cystathionine
G7045_RS07420	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
G7045_RS07425	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
G7045_RS07430	ENOG4105BZU	Histidine kinase
G7045_RS07435	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
G7045_RS07445	ENOG4105BZU	Histidine kinase
G7045_RS07460	ENOG4105D3G	Pseudouridine synthase
G7045_RS07465	ENOG4105CJB	Exodeoxyribonuclease I
G7045_RS07470	ENOG4105CVE	Lytic murein transglycosylase
G7045_RS07480	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
G7045_RS07495	ENOG4105NRA	50s ribosomal protein l31 type b
G7045_RS07505	ENOG4107QI1	Mate efflux family protein
G7045_RS07510	ENOG4105BZU	Histidine kinase
G7045_RS07515	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7045_RS07520	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
G7045_RS07525	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
G7045_RS07530	ENOG4105E2Z	phosphate ABC transporter (Permease
G7045_RS07535	ENOG4105C8U	phosphate abc transporter
G7045_RS07540	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
G7045_RS07550	ENOG4105C9X	ppx gppa phosphatase
G7045_RS07590	ENOG4105CHU	acetyl-coa acetyltransferase
G7045_RS07595	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7045_RS07600	ENOG4105C2J	ABC transporter
G7045_RS07605	ENOG4105C0Z	ABC transporter
G7045_RS07615	ENOG4105C32	Amino acid ABC transporter (Permease)
G7045_RS07620	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS07630	ENOG4105IJJ	transcriptional regulator, crp fnr family
G7045_RS07635	ENOG4105E0X	reductase
G7045_RS07640	ENOG4107835	probably involved in intracellular septation (By similarity)
G7045_RS07650	ENOG4107TF3	peptidylprolyl cis-trans isomerase
G7045_RS07660	ENOG4105CGY	Dna recombination protein
G7045_RS07670	ENOG4108WFY	phasin family
G7045_RS07675	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
G7045_RS07680	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
G7045_RS07685	ENOG41069M3	Transcriptional regulator
G7045_RS07690	ENOG4108Z6Z	Transcriptional regulator
G7045_RS07710	ENOG4105UTB	Blue (Type 1) copper domain protein
G7045_RS07720	ENOG4105KXX	peptidase s58 dmpa
G7045_RS07730	ENOG4105C5H	ABC transporter
G7045_RS07735	ENOG4105C1J	atp-dependent rna helicase
G7045_RS07745	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
G7045_RS07755	ENOG4105K70	DNA-binding protein
G7045_RS07765	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
G7045_RS07775	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7045_RS07780	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G7045_RS07795	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
G7045_RS07800	ENOG4108MN8	Membrane
G7045_RS07810	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
G7045_RS07815	ENOG4105CCI	Myosin-Cross-Reactive Antigen
G7045_RS07820	ENOG4105NBK	UPF0345 protein
G7045_RS07825	ENOG4105CDH	Citrulline--aspartate ligase
G7045_RS07830	ENOG4105EX9	Membrane
G7045_RS07835	ENOG4105CR8	Transcriptional regulator
G7045_RS07850	ENOG4108VPT	UPF0234 protein
G7045_RS07860	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
G7045_RS07865	ENOG4108Z66	YbaK ebsC protein
G7045_RS07875	ENOG4105CD8	aminopeptidase N
G7045_RS07880	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G7045_RS07910	ENOG41083KI	ribonuclease, T2
G7045_RS07970	ENOG4107QJE	Chromosome Partitioning Protein
G7045_RS08095	ENOG4105DFP	Integrase
G7045_RS08100	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
G7045_RS08105	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
G7045_RS08115	ENOG4105VDB	UPF0125 protein
G7045_RS08120	ENOG4108Z1B	Cyclase dehydrase
G7045_RS08125	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
G7045_RS08130	ENOG4105E39	Enoyl-CoA hydratase
G7045_RS08135	ENOG4105UYK	outer membrane protein a
G7045_RS08140	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7045_RS08145	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
G7045_RS08160	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
G7045_RS08165	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
G7045_RS08180	ENOG4105CFV	Tetratricopeptide repeat protein
G7045_RS08190	ENOG4105D65	subunit l
G7045_RS08195	ENOG4108ZE9	Monovalent cation H antiporter subunit C
G7045_RS08200	ENOG4107R4Z	monovalent cation h antiporter subunit d
G7045_RS08210	ENOG4105W4C	monovalent cation H antiporter subunit F
G7045_RS08225	ENOG4107Z6W	Protein CrcB homolog
G7045_RS08230	ENOG41061WM	D-Alanyl-D-Alanine
G7045_RS08235	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7045_RS08240	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G7045_RS08245	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
G7045_RS08250	ENOG4108ZP8	Acetolactate synthase small subunit
G7045_RS08255	ENOG4105C7K	acetolactate synthase
G7045_RS08260	ENOG4108SF5	RNA Polymerase
G7045_RS08280	ENOG41080IJ	Diacylglycerol kinase
G7045_RS08285	ENOG4108URH	decarboxylase
G7045_RS08290	ENOG4108YZA	Nitrogen regulatory protein pii
G7045_RS08360	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS08400	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7045_RS08405	ENOG4107ZSV	Receptor
G7045_RS08420	ENOG4105K70	DNA-binding protein
G7045_RS08510	ENOG4107RSM	transcriptional regulator
G7045_RS08615	ENOG4108UQ8	endoribonuclease L-psp
G7045_RS08625	ENOG4105ETT	transcriptional Regulator, LysR family
G7045_RS08630	ENOG4108J4B	Beta-lactamase
G7045_RS08675	ENOG4105FA0	parb-like partition protein
G7045_RS08795	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
G7045_RS08805	ENOG4105DTD	Dehydrogenase
G7045_RS08820	ENOG4105D64	Mechanosensitive ion channel
G7045_RS08830	ENOG4105DGU	Histone deacetylase
G7045_RS08835	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
G7045_RS08845	ENOG4105F8C	transglutaminase domain-containing protein
G7045_RS08850	ENOG4105CVE	Lytic murein transglycosylase
G7045_RS08855	ENOG4105ES9	amino acid
G7045_RS08860	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
G7045_RS08865	ENOG4105C2X	Arabinose 5-phosphate isomerase
G7045_RS08870	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G7045_RS08875	ENOG4108I0Q	anthranilate phosphoribosyltransferase
G7045_RS08880	ENOG4105CBX	hi0933 family
G7045_RS08885	ENOG4105VCC	30S ribosomal protein S21
G7045_RS08900	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
G7045_RS08910	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
G7045_RS08920	ENOG4105VRT	cytoplasmic protein
G7045_RS08925	ENOG4107JHD	SlyX family
G7045_RS08930	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
G7045_RS08935	ENOG4105CSM	endonuclease III
G7045_RS08945	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
G7045_RS08950	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
G7045_RS08960	ENOG4105DR9	pseudouridine synthase
G7045_RS08965	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
G7045_RS08980	ENOG4105D9M	gamma-glutamylcysteine synthetase
G7045_RS08985	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
G7045_RS08995	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
G7045_RS09000	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
G7045_RS09005	ENOG4107YIM	Involved in the transcription termination process (By similarity)
G7045_RS09010	ENOG4105CHM	Aminotransferase
G7045_RS09015	ENOG4107YD3	Thioesterase
G7045_RS09020	ENOG4105E02	MotA TolQ exbB proton channel
G7045_RS09025	ENOG4105M8F	Biopolymer transport protein exbD tolR
G7045_RS09035	ENOG4105CFP	Peptidase U32
G7045_RS09040	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS09050	ENOG4105C0D	helicase
G7045_RS09055	ENOG4107QIJ	Aconitate hydratase 2
G7045_RS09070	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
G7045_RS09075	ENOG4105FDP	GntR family transcriptional regulator
G7045_RS09080	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
G7045_RS09095	ENOG4105E33	succinate dehydrogenase
G7045_RS09100	ENOG41060IS	Flavinator of succinate dehydrogenase
G7045_RS09105	ENOG4105BZN	citrate synthase
G7045_RS09110	ENOG4105DIJ	Phosphoethanolamine transferase
G7045_RS09115	ENOG4105NXH	GreA GreB family elongation factor
G7045_RS09125	ENOG4108EC8	DNA internalization-related competence protein ComEC
G7045_RS09135	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS09140	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7045_RS09155	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7045_RS09170	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
G7045_RS09175	ENOG4105GJM	(LipO)protein
G7045_RS09190	ENOG4105EZE	Cupin 4 family protein
G7045_RS09195	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G7045_RS09210	ENOG4105BZS	acriflavin resistance protein
G7045_RS09215	ENOG4105BZS	acriflavin resistance protein
G7045_RS09225	ENOG4105F4R	Transcriptional regulator mode
G7045_RS09230	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
G7045_RS09235	ENOG4105E0C	molybdate abc transporter
G7045_RS09240	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
G7045_RS09250	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G7045_RS09260	ENOG4105CH5	extracellular solute-binding protein, family 7
G7045_RS09265	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
G7045_RS09275	ENOG41086K9	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
G7045_RS09290	ENOG4105KHC	sulfurtransferase
G7045_RS09295	ENOG4105GEH	Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity)
G7045_RS09300	ENOG4106CIA	Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region
G7045_RS09310	ENOG4107S1E	Beta-lactamase
G7045_RS09340	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
G7045_RS09345	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
G7045_RS09355	ENOG4105ECF	c-methyltransferase
G7045_RS09385	ENOG4107KET	secretion protein, HlyD family
G7045_RS09405	ENOG41067HZ	cytochrome C, class I
G7045_RS09425	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
G7045_RS09430	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
G7045_RS09440	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7045_RS09460	ENOG4108ZF3	Phosphatase
G7045_RS09465	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7045_RS09495	ENOG4105C1G	acyl-Coa dehydrogenase
G7045_RS09505	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
G7045_RS09510	ENOG4105C6T	cysteine synthase
G7045_RS09525	ENOG4105C1G	acyl-Coa dehydrogenase
G7045_RS09565	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
G7045_RS09580	ENOG4105DJ0	Poly(A) Polymerase
G7045_RS09590	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
G7045_RS09595	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
G7045_RS09605	ENOG4105SHT	UspA domain-containing protein
G7045_RS09615	ENOG4105CJR	Integral membrane protein (MviN
G7045_RS09620	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
G7045_RS09630	ENOG4105C8Y	Acetylornithine aminotransferase
G7045_RS09635	ENOG4105DBV	ornithine carbamoyltransferase
G7045_RS09640	ENOG4105PI0	Ferredoxin
G7045_RS09645	ENOG4105C29	acyl-CoA thioesterase
G7045_RS09650	ENOG4105PI0	Ferredoxin
G7045_RS09655	ENOG4105MSY	salicylate hydroxylase
G7045_RS09660	ENOG4107QM5	aconitate hydratase
G7045_RS09675	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
G7045_RS09680	ENOG4105CJ2	(LipO)protein
G7045_RS09685	ENOG4105MPD	Cytochrome
G7045_RS09705	ENOG4105DH4	Periplasmic copper-binding protein
G7045_RS09710	ENOG4105CIG	ABC transporter
G7045_RS09715	ENOG4108T0W	nitrous oxide maturation protein NosY
G7045_RS09730	ENOG4105C1J	atp-dependent rna helicase
G7045_RS09735	ENOG4105DHP	deoxycytidine triphosphate deaminase
G7045_RS09760	ENOG4105UIB	(ABC) transporter
G7045_RS09765	ENOG4108JQ9	ABC transporter
G7045_RS09770	ENOG4105BZU	Histidine kinase
G7045_RS09785	ENOG4108VIA	integral membrane protein
G7045_RS09795	ENOG4105CRK	lysyL-tRNA synthetase
G7045_RS09810	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
G7045_RS09815	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
G7045_RS09820	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
G7045_RS09825	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
G7045_RS09830	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
G7045_RS09835	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
G7045_RS09845	ENOG4105C3F	Signal peptidase i
G7045_RS09850	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
G7045_RS09855	ENOG4105C0H	protease
G7045_RS09865	ENOG4105EMN	RNA polymerase sigma factor
G7045_RS09875	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
G7045_RS09880	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
G7045_RS09885	ENOG4105CHR	reductase
G7045_RS09890	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
G7045_RS09895	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
G7045_RS09900	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
G7045_RS09905	ENOG4105VGS	50s ribosomal protein l32
G7045_RS09910	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
G7045_RS09915	ENOG4108UHJ	MAF-like protein
G7045_RS09920	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
G7045_RS09935	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
G7045_RS09950	ENOG4105EI2	Pseudouridine synthase
G7045_RS09955	ENOG4105C03	ribonuclease
G7045_RS09960	ENOG4105D1Q	UPF0246 protein
G7045_RS09970	ENOG4105EPD	Oligopeptide transporter, Opt family
G7045_RS09975	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
G7045_RS09980	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G7045_RS09985	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
G7045_RS09990	ENOG4105BZ4	penicillin-binding protein
G7045_RS10020	ENOG4105CH7	arginosuccinase
G7045_RS10030	ENOG4108NEV	two component transcriptional regulator, LytTR family
G7045_RS10050	ENOG4105C2M	dna polymerase I
G7045_RS10065	ENOG4105CUV	Homoserine Kinase
G7045_RS10080	ENOG4105C4R	Atp-dependent dna helicase
G7045_RS10085	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
G7045_RS10095	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
G7045_RS10105	ENOG4105C2C	drug resistance transporter, Bcr CflA
G7045_RS10110	ENOG4105BZU	Histidine kinase
G7045_RS10115	ENOG4105C1J	atp-dependent rna helicase
G7045_RS10120	ENOG4105CP9	extracellular ligand-binding receptor
G7045_RS10125	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
G7045_RS10130	ENOG4105D0M	Protease HtpX homolog
G7045_RS10135	ENOG41090A4	Pterin carbinolamine dehydratase
G7045_RS10140	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
G7045_RS10145	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
G7045_RS10150	ENOG4105P8F	nudix hydrolase
G7045_RS10155	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
G7045_RS10160	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
G7045_RS10165	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
G7045_RS10170	ENOG4105K5M	30s ribosomal protein S16
G7045_RS10175	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
G7045_RS10180	ENOG4105D60	lipoprotein releasing system transmembrane protein
G7045_RS10190	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
G7045_RS10195	ENOG4105EXC	Acyl-transferase
G7045_RS10200	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS10205	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS10210	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS10215	ENOG4105DB7	PHP domain protein
G7045_RS10220	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
G7045_RS10225	ENOG4108Z4T	Peptidase M50
G7045_RS10230	ENOG4105C31	Tryptophanyl-tRNA synthetase
G7045_RS10245	ENOG4105DFP	Integrase
G7045_RS10255	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
G7045_RS10295	ENOG4105VZ1	Replication Protein
G7045_RS10360	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
G7045_RS10515	ENOG4105ED4	portal protein
G7045_RS10550	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
G7045_RS10560	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
G7045_RS10565	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
G7045_RS10570	ENOG4105W5Q	DNA repair protein (RadC
G7045_RS10580	ENOG4105C98	muts2 protein
G7045_RS10610	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
G7045_RS10620	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
G7045_RS10625	ENOG4108MG3	formate dehydrogenase
G7045_RS10630	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
G7045_RS10635	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
G7045_RS10645	ENOG4105EM7	Selenocysteine-specific translation elongation factor
G7045_RS10660	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
G7045_RS10665	ENOG4105EMN	RNA polymerase sigma factor
G7045_RS10670	ENOG4105BZU	Histidine kinase
G7045_RS10680	ENOG4105EUJ	GTP cyclohydrolase i
G7045_RS10685	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
G7045_RS10690	ENOG4105D1F	ATP-binding protein
G7045_RS10705	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
G7045_RS10715	ENOG4107S7U	Sulfide dehydrogenase
G7045_RS10740	ENOG4105CP9	extracellular ligand-binding receptor
G7045_RS10745	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
G7045_RS10750	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
G7045_RS10755	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G7045_RS10760	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
G7045_RS10765	ENOG4105BZU	Histidine kinase
G7045_RS10770	ENOG4108ZXC	Two component transcriptional regulator, luxr family
G7045_RS10780	ENOG4108ZX5	transcriptional regulator
G7045_RS10805	ENOG4107GJV	short-chain dehydrogenase reductase
G7045_RS10810	ENOG4107RGH	Aldehyde dehydrogenase
G7045_RS10815	ENOG4105C09	Bile acid
G7045_RS10840	ENOG4108IYU	L-aspartate oxidase
G7045_RS10845	ENOG4108Z9W	Outer membrane porin
G7045_RS10850	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
G7045_RS10860	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
G7045_RS10895	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
G7045_RS10900	ENOG4105MJ2	Competence protein
G7045_RS10905	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
G7045_RS10920	ENOG410829K	Lysine exporter protein (Lyse ygga)
G7045_RS10925	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
G7045_RS10930	ENOG4105EN6	Membrane
G7045_RS10940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
G7045_RS10970	ENOG4105K89	arsenate reductase
G7045_RS10975	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
G7045_RS10980	ENOG4108UCS	ABC, transporter
G7045_RS10990	ENOG4105CD3	dihydroorotase
G7045_RS10995	ENOG4105CXT	aspartate transcarbamylase
G7045_RS11000	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
G7045_RS11005	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
G7045_RS11010	ENOG4108UJU	UPF0301 protein
G7045_RS11020	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS11025	ENOG4108V3W	Chemotaxis protein, CheW
G7045_RS11030	ENOG4105M3Z	response regulator
G7045_RS11035	ENOG4108UNF	response regulator
G7045_RS11050	ENOG4105DC1	bifunctional purine biosynthesis protein purh
G7045_RS11055	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
G7045_RS11060	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
G7045_RS11065	ENOG4105W39	Membrane
G7045_RS11070	ENOG4105FR1	rard protein
G7045_RS11075	ENOG4105C3G	gtp-binding protein
G7045_RS11080	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
G7045_RS11095	ENOG4105E39	Enoyl-CoA hydratase
G7045_RS11105	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
G7045_RS11130	ENOG4105KHS	type IV fimbrial pilin protein
G7045_RS11155	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7045_RS11160	ENOG4105CRE	cytochrome C
G7045_RS11170	ENOG4107TUY	Histidine kinase
G7045_RS11175	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7045_RS11185	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7045_RS11190	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
G7045_RS11200	ENOG4107T4Z	adenosine kinase
G7045_RS11210	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
G7045_RS11215	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
G7045_RS11220	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
G7045_RS11225	ENOG4107QX9	Thiol disulfide interChange protein
G7045_RS11235	ENOG4105DFU	Cell wall formation (By similarity)
G7045_RS11245	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G7045_RS11255	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
G7045_RS11260	ENOG4105CNI	cell division protein FtsW
G7045_RS11280	ENOG4105E2X	shikimate dehydrogenase
G7045_RS11285	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
G7045_RS11290	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
G7045_RS11295	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS11305	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS11310	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
G7045_RS11320	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
G7045_RS11325	ENOG4105VFU	Rna-binding protein
G7045_RS11330	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
G7045_RS11335	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
G7045_RS11340	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
G7045_RS11345	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
G7045_RS11350	ENOG4105CPF	Cell wall formation (By similarity)
G7045_RS11355	ENOG4105DFU	Cell wall formation (By similarity)
G7045_RS11360	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
G7045_RS11365	ENOG4105CNI	cell division protein FtsW
G7045_RS11370	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
G7045_RS11375	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
G7045_RS11380	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
G7045_RS11385	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
G7045_RS11400	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
G7045_RS11405	ENOG4108V6E	Cell division protein mraZ
G7045_RS11410	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
G7045_RS11415	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
G7045_RS11430	ENOG4105CKI	cobalamin synthesis protein
G7045_RS11440	ENOG4105C08	Histidine kinase
G7045_RS11445	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
G7045_RS11455	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
G7045_RS11480	ENOG4105BZU	Histidine kinase
G7045_RS11495	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
G7045_RS11505	ENOG4105DZ0	fad dependent oxidoreductase
G7045_RS11510	ENOG4105D0M	Protease HtpX homolog
G7045_RS11525	ENOG4105EKE	dihydroorotase
G7045_RS11530	ENOG4105CDA	abc transporter atp-binding protein
G7045_RS11535	ENOG4105DRP	amino acid AbC transporter
G7045_RS11540	ENOG4105EAD	ABC transporter
G7045_RS11545	ENOG4107RP9	extracellular solute-binding protein, family 3
G7045_RS11555	ENOG4107YNJ	LysR family Transcriptional regulator
G7045_RS11565	ENOG4108JJ7	ABC transporter
G7045_RS11570	ENOG4108VUY	thioesterase Superfamily protein
G7045_RS11575	ENOG4105E39	Enoyl-CoA hydratase
G7045_RS11585	ENOG4105CHU	acetyl-coa acetyltransferase
G7045_RS11600	ENOG4105CSU	acyl-Coa dehydrogenase
G7045_RS11610	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
G7045_RS11620	ENOG4105CEY	Amp-dependent synthetase and ligase
G7045_RS11635	ENOG4105BZU	Histidine kinase
G7045_RS11640	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
G7045_RS11645	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
G7045_RS11650	ENOG41080T7	secreted protein
G7045_RS11665	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
G7045_RS11670	ENOG4108ETV	ABC transporter
G7045_RS11680	ENOG4105CB5	ATP-dependent DNA helicase recG
G7045_RS11685	ENOG4105CPI	Metal Dependent Phosphohydrolase
G7045_RS11690	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
G7045_RS11715	ENOG4105E93	esterase
G7045_RS11725	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
G7045_RS11730	ENOG4105E27	serine threonine protein kinase
G7045_RS11745	ENOG4105KB2	stringent starvation protein b
G7045_RS11750	ENOG4107MKT	Stringent starvation protein a
G7045_RS11755	ENOG4105EIX	cytochrome c1
G7045_RS11760	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G7045_RS11765	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
G7045_RS11770	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
G7045_RS11775	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
G7045_RS11780	ENOG4107QNR	UPF0135 protein
G7045_RS11785	ENOG4105C0H	protease
G7045_RS11790	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
G7045_RS11795	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
G7045_RS11800	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
G7045_RS11805	ENOG4105K59	histidine triad (HIT) protein
G7045_RS11815	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
G7045_RS11820	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
G7045_RS11825	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
G7045_RS11830	ENOG4105CMR	udp-glucose 4-epimerase
G7045_RS11860	ENOG4108I69	Glycosyl transferases group 1
G7045_RS11880	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
G7045_RS11890	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
G7045_RS11895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
G7045_RS11905	ENOG4105C94	Transporter
G7045_RS11920	ENOG4105DFS	Conserved Protein
G7045_RS11925	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
G7045_RS11930	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
G7045_RS11935	ENOG4105VFK	BolA family
G7045_RS11940	ENOG4105E3A	(ABC) transporter
G7045_RS11945	ENOG4105DA5	(ABC) transporter
G7045_RS11950	ENOG4105BZU	Histidine kinase
G7045_RS11965	ENOG410903C	(LipO)protein
G7045_RS11970	ENOG4107PE3	Mammalian cell entry related domain protein
G7045_RS11975	ENOG4105CY3	ABC transporter, permease
G7045_RS11980	ENOG4105DHJ	ABC, transporter
G7045_RS11985	ENOG4105CDA	abc transporter atp-binding protein
G7045_RS11990	ENOG4105E5Q	amino acid AbC transporter
G7045_RS11995	ENOG4105E89	ABC transporter
G7045_RS12025	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
G7045_RS12030	ENOG4107QYA	phosphate
G7045_RS12035	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
G7045_RS12045	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
G7045_RS12050	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS12055	ENOG4105CD5	CoA-binding domain protein
G7045_RS12070	ENOG4105R8A	Heat shock protein
G7045_RS12075	ENOG4105CDA	abc transporter atp-binding protein
G7045_RS12080	ENOG4105DRP	amino acid AbC transporter
G7045_RS12085	ENOG4105EAB	amino acid AbC transporter
G7045_RS12100	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
G7045_RS12105	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
G7045_RS12110	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
G7045_RS12125	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
G7045_RS12130	ENOG4105C9A	Phoh family
G7045_RS12135	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
G7045_RS12140	ENOG4105EJ9	Membrane
G7045_RS12150	ENOG4108ZT0	50S ribosomal protein l17
G7045_RS12155	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7045_RS12160	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
G7045_RS12165	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
G7045_RS12170	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7045_RS12180	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
G7045_RS12185	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
G7045_RS12190	ENOG4105VPB	50S ribosomal protein L30
G7045_RS12195	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
G7045_RS12200	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
G7045_RS12205	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
G7045_RS12210	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
G7045_RS12215	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
G7045_RS12220	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7045_RS12225	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
G7045_RS12230	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
G7045_RS12235	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G7045_RS12250	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
G7045_RS12265	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
G7045_RS12270	ENOG4105E98	transcriptional regulator DeoR family
G7045_RS12275	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
G7045_RS12285	ENOG4105KHS	type IV fimbrial pilin protein
G7045_RS12375	ENOG4106NZI	LysR family Transcriptional regulator
G7045_RS12415	ENOG4105D0M	Protease HtpX homolog
G7045_RS12445	ENOG4107QJE	Chromosome Partitioning Protein
G7045_RS12490	ENOG4105VUN	Transcriptional regulator
G7045_RS12535	ENOG4107Y80	Major Facilitator superfamily
G7045_RS12550	ENOG4105DFS	Conserved Protein
G7045_RS12560	ENOG4105II7	pyrroline-5-carboxylate reductase
G7045_RS12565	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
G7045_RS12590	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
G7045_RS12600	ENOG4105BZU	Histidine kinase
G7045_RS12605	ENOG4105FYV	Amp nucleosidase
G7045_RS12615	ENOG4108VAU	general secretion pathway protein G
G7045_RS12655	ENOG4105GVR	general secretion pathway protein D
G7045_RS12660	ENOG4107QHF	type ii secretion system protein e
G7045_RS12670	ENOG4105D7Q	type ii secretion system
G7045_RS12690	ENOG4105BZ1	(ABC) transporter
G7045_RS12705	ENOG4108RH0	Crea protein
G7045_RS12745	ENOG4105C5H	ABC transporter
G7045_RS12750	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
G7045_RS12755	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
G7045_RS12760	ENOG4105BZU	Histidine kinase
G7045_RS12765	ENOG4108V3W	Chemotaxis protein, CheW
G7045_RS12770	ENOG4105CBS	Chea signal transduction histidine kinase
G7045_RS12775	ENOG4107YTP	response regulator receiver protein
G7045_RS12785	ENOG4105BZU	Histidine kinase
G7045_RS12790	ENOG4108KX4	response regulator
G7045_RS12795	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
G7045_RS12800	ENOG4105VS8	Flagellar biosynthetic protein fliq
G7045_RS12805	ENOG4105CN7	Flagellar biosynthetic protein FliP
G7045_RS12815	ENOG4105DD5	Flagellar motor switch protein
G7045_RS12820	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G7045_RS12825	ENOG4107ZI8	flagellar basal body-associated protein flil
G7045_RS12840	ENOG4108JIR	Flagellum-specific ATP synthase
G7045_RS12850	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
G7045_RS12855	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
G7045_RS12860	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
G7045_RS12870	ENOG4105MQ3	flagellar protein FliS
G7045_RS12875	ENOG4105DTS	flagellar hook-associated
G7045_RS12880	ENOG4105I03	Flagellin
G7045_RS12885	ENOG4105I03	Flagellin
G7045_RS12920	ENOG4105FAW	cDP-glucose 4,6-dehydratase
G7045_RS12925	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
G7045_RS12930	ENOG4107RD7	Flagellar Motor Protein, MotA
G7045_RS12935	ENOG4105ER2	Ompa motb domain protein
G7045_RS12940	ENOG4108VYJ	response regulator receiver protein
G7045_RS12945	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
G7045_RS12950	ENOG4105D00	flagellar biosynthetic protein flhB
G7045_RS12955	ENOG4105D7B	Flagellar biosynthesis protein flha
G7045_RS12960	ENOG4105FZW	flagellar biosynthesis regulator FlhF
G7045_RS12970	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
G7045_RS12990	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
G7045_RS12995	ENOG4108ZC9	flagellar basal-body rod protein flgc
G7045_RS13000	ENOG4105W00	Flagellar hook capping protein
G7045_RS13005	ENOG4105BZE	flagellar hook protein, FlgE
G7045_RS13010	ENOG4108KPB	Flagellar basal-body rod protein FlgF
G7045_RS13015	ENOG4105CGA	flagellar basal-body rod protein FlgG
G7045_RS13020	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G7045_RS13025	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
G7045_RS13030	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
G7045_RS13035	ENOG4105E1Q	flagellar hook-associated protein
G7045_RS13040	ENOG4105DTJ	flagellar hook-associated protein
G7045_RS13085	ENOG4105C4R	Atp-dependent dna helicase
G7045_RS13100	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
G7045_RS13125	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
G7045_RS13130	ENOG4105DJV	ribulose-phosphate 3-epimerase
G7045_RS13135	ENOG4105NWN	ApaG protein
G7045_RS13150	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
G7045_RS13160	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
G7045_RS13175	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
G7045_RS13180	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
G7045_RS13185	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
G7045_RS13190	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
G7045_RS13200	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
G7045_RS13205	ENOG4105C25	Primosomal protein n'
G7045_RS13220	ENOG4107QP3	malate synthase g
G7045_RS13240	ENOG41084KP	4-oxalocrotonate tautomerase
G7045_RS13245	ENOG4105E7A	Glutamine amidotransferase
G7045_RS13255	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
G7045_RS13290	ENOG4105ES5	Histidine kinase
G7045_RS13300	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
G7045_RS13310	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7045_RS13315	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
G7045_RS13320	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
G7045_RS13325	ENOG4108VZM	50s ribosomal protein L10
G7045_RS13330	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
G7045_RS13335	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
G7045_RS13340	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
G7045_RS13345	ENOG4105PM1	preprotein translocase subunit SecE
G7045_RS13355	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G7045_RS13385	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
G7045_RS13390	ENOG4105BZS	acriflavin resistance protein
G7045_RS13395	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
G7045_RS13400	ENOG4105MPD	Cytochrome
G7045_RS13410	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
G7045_RS13415	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
G7045_RS13420	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
G7045_RS13425	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
G7045_RS13430	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7045_RS13440	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
G7045_RS13445	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
G7045_RS13455	ENOG4108Z43	UPF0250 protein
G7045_RS13460	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
G7045_RS13465	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
G7045_RS13480	ENOG4105DHJ	ABC, transporter
G7045_RS13490	ENOG4105EJ9	Membrane
G7045_RS13495	ENOG41066UZ	arginase EC 3.5.3.1
G7045_RS13500	ENOG4105CJN	penicillin-binding protein
G7045_RS13510	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
G7045_RS13520	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7045_RS13525	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
G7045_RS13530	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
G7045_RS13540	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
G7045_RS13545	ENOG4105CGK	Exodeoxyribonuclease III
G7045_RS13550	ENOG4107QHF	type ii secretion system protein e
G7045_RS13555	ENOG4105C5X	domain protein
G7045_RS13565	ENOG4108V06	Glutathione peroxidase
G7045_RS13575	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS13585	ENOG4105BZU	Histidine kinase
G7045_RS13590	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
G7045_RS13600	ENOG4105EU8	FAD linked oxidase domain protein
G7045_RS13610	ENOG4105BZU	Histidine kinase
G7045_RS13615	ENOG4108YZA	Nitrogen regulatory protein pii
G7045_RS13620	ENOG4105DP0	ferredoxin-NADP reductase
G7045_RS13625	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
G7045_RS13630	ENOG41080Z8	PHOSPHOCARRIER protein
G7045_RS13640	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7045_RS13655	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
G7045_RS13660	ENOG41084PQ	50s ribosomal protein l29
G7045_RS13665	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
G7045_RS13670	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
G7045_RS13675	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
G7045_RS13680	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
G7045_RS13685	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7045_RS13690	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
G7045_RS13695	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
G7045_RS13700	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
G7045_RS13705	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
G7045_RS13710	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
G7045_RS13715	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
G7045_RS13720	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
G7045_RS13725	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
G7045_RS13730	ENOG4105DZ1	carboxypeptidase
G7045_RS13735	ENOG4105DHZ	alpha beta
G7045_RS13750	ENOG4108YXA	Membrane
G7045_RS13760	ENOG4105D52	delta-aminolevulinic acid dehydratase
G7045_RS13765	ENOG4105D7N	magnesium and cobalt transport protein CorA
G7045_RS13780	ENOG4105CQB	FAD linked oxidase domain protein
G7045_RS13785	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
G7045_RS13790	ENOG4108CWB	sugar kinase ygcE
G7045_RS13795	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
G7045_RS13800	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
G7045_RS13810	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
G7045_RS13815	ENOG4105CM2	brancheD-chain amino acid aminotransferase
G7045_RS13830	ENOG4106WTF	Glycosyl transferase, family 2
G7045_RS13840	ENOG4105CBP	Major Facilitator
G7045_RS13845	ENOG4105E0F	Histidine kinase
G7045_RS13850	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
G7045_RS13855	ENOG4105EYM	Major Facilitator superfamily
G7045_RS13870	ENOG4105C3R	Methionine synthase
G7045_RS13880	ENOG4105CH6	catalase
G7045_RS13885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
G7045_RS13900	ENOG4105D05	Receptor
G7045_RS13925	ENOG4105D82	Glutamate dehydrogenase
G7045_RS13935	ENOG4105C3R	Methionine synthase
G7045_RS13940	ENOG4105C9U	ATP-dependent DNA helicase RecQ
G7045_RS13955	ENOG4105EUP	HipA domain protein
G7045_RS13990	ENOG4105C7B	Threonine dehydratase
G7045_RS13995	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
G7045_RS14005	ENOG4108WBT	adenosyltransferase
G7045_RS14010	ENOG4105KA0	thioesterase Superfamily protein
G7045_RS14025	ENOG4105C2W	permease
G7045_RS14035	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
G7045_RS14040	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
G7045_RS14045	ENOG4107QMS	site-determining protein
G7045_RS14050	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
G7045_RS14070	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
G7045_RS14125	ENOG4105FA0	parb-like partition protein
G7045_RS14150	ENOG4107QJE	Chromosome Partitioning Protein
G7045_RS14155	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
G7045_RS14160	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
G7045_RS14175	ENOG4105KRS	Proteinase inhibitor
G7045_RS14180	ENOG4108K3A	Glutathione S-transferase
G7045_RS14185	ENOG4105C8Q	Methyl-accepting chemotaxis
G7045_RS14215	ENOG4105CB5	ATP-dependent DNA helicase recG
G7045_RS14220	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
G7045_RS14235	ENOG4105DH7	May be involved in recombination (By similarity)
G7045_RS14245	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
G7045_RS14250	ENOG4105K4H	Nlp p60 protein
G7045_RS14255	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
G7045_RS14265	ENOG4108ZCF	integral membrane protein
G7045_RS14270	ENOG41086DT	Membrane protein of unknown function
G7045_RS14275	ENOG4105ERG	peptidase m48, ste24p
G7045_RS14280	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
G7045_RS14290	ENOG4108S0S	Nucleotidyl transferase
G7045_RS14295	ENOG4105CV1	Transketolase (EC 2.2.1.1)
G7045_RS14300	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
G7045_RS14310	ENOG4108YZY	peptidylprolyl cis-trans isomerase
G7045_RS14315	ENOG4105EUB	pirin domain protein
G7045_RS14330	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
G7045_RS14365	ENOG4105E0F	Histidine kinase
G7045_RS14370	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
G7045_RS14400	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
G7045_RS14435	ENOG4105C6K	Malic enzyme
G7045_RS14450	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
G7045_RS14455	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
G7045_RS14460	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
G7045_RS14465	ENOG4105EHM	Aminoglycoside phosphotransferase
G7045_RS14470	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
G7045_RS14505	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
G7045_RS14510	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
G7045_RS14515	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
G7045_RS14520	ENOG4105VG0	50S ribosomal protein l34
G7045_RS14530	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
G7045_RS14535	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
G7045_RS14540	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
G7045_RS14560	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
G7045_RS14565	ENOG4105BZU	Histidine kinase
G7045_RS14575	ENOG4105C2X	Arabinose 5-phosphate isomerase
G7045_RS14580	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
G7045_RS14590	ENOG4107FW0	short-chain dehydrogenase reductase
G7045_RS14595	ENOG4105VFU	Rna-binding protein
G7045_RS14600	ENOG4105VFU	Rna-binding protein