locus-tag	class	description
AJS_RS00015	COG0791	NLP P60 protein
AJS_RS00020	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AJS_RS00050	COG2974	May be involved in recombination
AJS_RS00055	COG1301	dicarboxylic acid transport
AJS_RS00060	COG2198	Histidine kinase
AJS_RS00060	COG0784	Response regulator, receiver
AJS_RS00060	COG2205	protein histidine kinase activity
AJS_RS00070	COG0700	Nucleoside recognition
AJS_RS00080	COG0183	Belongs to the thiolase family
AJS_RS00095	COG0789	Transcriptional regulator
AJS_RS00110	COG0840	transmembrane signaling receptor activity
AJS_RS00125	COG0625	glutathione transferase activity
AJS_RS00140	COG0445	tRNA wobble uridine modification
AJS_RS00145	COG0357	Ribosomal RNA small subunit methyltransferase G
AJS_RS00155	COG1192	Involved in chromosome partitioning
AJS_RS00165	COG1475	DNA binding
AJS_RS00210	COG0277	FAD linked oxidase domain protein
AJS_RS00225	COG2096	Adenosyltransferase
AJS_RS00230	COG2050	protein possibly involved in aromatic compounds catabolism
AJS_RS00250	COG2233	PERMEase
AJS_RS00280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AJS_RS00285	COG0583	DNA-binding transcription factor activity
AJS_RS00300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS00305	COG1012	belongs to the aldehyde dehydrogenase family
AJS_RS00305	COG2030	dehydratase
AJS_RS00315	COG1960	acyl-CoA dehydrogenase activity
AJS_RS00320	COG1960	acyl-CoA dehydrogenase activity
AJS_RS00330	COG1183	phosphatidylcholine synthase activity
AJS_RS00335	COG0850	regulation of cytokinetic process
AJS_RS00345	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AJS_RS00350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AJS_RS00365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AJS_RS00370	COG0583	DNA-binding transcription factor activity
AJS_RS00400	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
AJS_RS00405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AJS_RS00410	COG1960	acyl-CoA dehydrogenase activity
AJS_RS00425	COG0514	ATP-dependent DNA helicase (RecQ)
AJS_RS00465	COG3256	nitric oxide reductase
AJS_RS00470	COG3604	Transcriptional regulator
AJS_RS00480	COG1760	l-serine dehydratase
AJS_RS00490	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS00495	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS00530	COG0183	Belongs to the thiolase family
AJS_RS00550	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS00555	COG1024	Enoyl-CoA hydratase
AJS_RS00565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS00595	COG1960	acyl-CoA dehydrogenase activity
AJS_RS00600	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
AJS_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS00610	COG2030	dehydratase
AJS_RS00615	COG1024	Enoyl-CoA hydratase
AJS_RS00620	COG0427	acetyl-CoA hydrolase
AJS_RS00625	COG0183	Belongs to the thiolase family
AJS_RS00635	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS00655	COG1960	acyl-CoA dehydrogenase activity
AJS_RS00665	COG0583	DNA-binding transcription factor activity
AJS_RS00670	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS00680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AJS_RS00685	COG2326	polyphosphate kinase activity
AJS_RS00690	COG0583	DNA-binding transcription factor activity
AJS_RS00700	COG0583	DNA-binding transcription factor activity
AJS_RS00710	COG4829	muconolactone delta-isomerase
AJS_RS00730	COG0723	plastoquinol--plastocyanin reductase activity
AJS_RS00735	COG2204	response regulator
AJS_RS00745	COG2989	Protein conserved in bacteria
AJS_RS00750	COG3108	Peptidase M15
AJS_RS00755	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AJS_RS00775	COG0683	leucine binding
AJS_RS00785	COG0411	ABC transporter
AJS_RS00795	COG0583	DNA-binding transcription factor activity
AJS_RS00800	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS00805	COG0840	transmembrane signaling receptor activity
AJS_RS00820	COG0347	Belongs to the P(II) protein family
AJS_RS00825	COG0004	ammonium transporteR
AJS_RS00835	COG0277	FAD linked oxidase domain protein
AJS_RS00845	COG0247	lactate metabolic process
AJS_RS00870	COG0386	Belongs to the glutathione peroxidase family
AJS_RS00880	COG0477	Major facilitator Superfamily
AJS_RS00885	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AJS_RS00895	COG0625	glutathione transferase activity
AJS_RS00935	COG1216	Glycosyl transferase, family 2
AJS_RS00935	COG1442	glycosyl transferase family 8
AJS_RS00955	COG0477	Major facilitator Superfamily
AJS_RS00960	COG2258	MOSC domain
AJS_RS00970	COG2205	protein histidine kinase activity
AJS_RS00975	COG0745	RESPONSE REGULATOR receiver
AJS_RS00985	COG3645	SOS response
AJS_RS01020	COG0501	Belongs to the peptidase M48B family
AJS_RS01025	COG1802	Transcriptional regulator
AJS_RS01120	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AJS_RS01125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AJS_RS01145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AJS_RS01155	COG1960	acyl-CoA dehydrogenase activity
AJS_RS01170	COG0708	Exodeoxyribonuclease III
AJS_RS01175	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AJS_RS01185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AJS_RS01190	COG0154	amidase activity
AJS_RS01195	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AJS_RS01200	COG1077	Cell shape determining protein MreB Mrl
AJS_RS01210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AJS_RS01215	COG0768	penicillin binding
AJS_RS01225	COG1126	abc transporter atp-binding protein
AJS_RS01230	COG0765	amino acid transport
AJS_RS01235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AJS_RS01255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AJS_RS01260	COG1127	ABC transporter
AJS_RS01275	COG3237	CsbD-like
AJS_RS01290	COG3706	GGDEF domain
AJS_RS01290	COG4251	negative regulation of phosphorylation
AJS_RS01290	COG2203	Gaf domain
AJS_RS01290	COG5001	Diguanylate cyclase
AJS_RS01295	COG2095	MarC family integral membrane protein
AJS_RS01300	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS01305	COG0412	Dienelactone hydrolase
AJS_RS01315	COG1566	PFAM secretion protein HlyD family protein
AJS_RS01320	COG1538	Outer membrane efflux protein
AJS_RS01325	COG1846	Transcriptional regulator
AJS_RS01330	COG0598	Magnesium transport protein CorA
AJS_RS01345	COG1981	membrane
AJS_RS01360	COG2945	thiolester hydrolase activity
AJS_RS01365	COG1686	Belongs to the peptidase S11 family
AJS_RS01370	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AJS_RS01375	COG0049	tRNA binding
AJS_RS01380	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AJS_RS01385	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AJS_RS01390	COG0051	transcription antitermination factor activity, RNA binding
AJS_RS01395	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AJS_RS01400	COG0088	Forms part of the polypeptide exit tunnel
AJS_RS01405	COG0089	rRNA binding
AJS_RS01410	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AJS_RS01415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AJS_RS01420	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AJS_RS01425	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AJS_RS01430	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AJS_RS01435	COG0255	Belongs to the universal ribosomal protein uL29 family
AJS_RS01440	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AJS_RS01445	COG0678	peroxiredoxin activity
AJS_RS01450	COG0456	acetyltransferase
AJS_RS01465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AJS_RS01485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AJS_RS01490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AJS_RS01495	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AJS_RS01500	COG0321	lipoyl(octanoyl) transferase activity
AJS_RS01505	COG2921	Belongs to the UPF0250 family
AJS_RS01515	COG0356	it plays a direct role in the translocation of protons across the membrane
AJS_RS01525	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AJS_RS01530	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AJS_RS01535	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AJS_RS01540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AJS_RS01545	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AJS_RS01550	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AJS_RS01560	COG1793	dna ligase
AJS_RS01565	COG1201	RNA secondary structure unwinding
AJS_RS01605	COG3245	cytochrome
AJS_RS01620	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AJS_RS01660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AJS_RS01675	COG1063	alcohol dehydrogenase
AJS_RS01685	COG0121	glutamine amidotransferase
AJS_RS01690	COG1942	4-Oxalocrotonate Tautomerase
AJS_RS01700	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AJS_RS01725	COG0018	arginyl-trna synthetase
AJS_RS01745	COG1137	ATPase activity
AJS_RS01750	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AJS_RS01770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AJS_RS01775	COG3012	SEC-C Motif Domain Protein
AJS_RS01775	COG3318	Belongs to the UPF0149 family
AJS_RS01780	COG1058	Belongs to the CinA family
AJS_RS01780	COG1546	Belongs to the CinA family
AJS_RS01785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AJS_RS01795	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AJS_RS01810	COG2967	ApaG domain
AJS_RS01815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AJS_RS01825	COG0546	phosphoglycolate phosphatase activity
AJS_RS01830	COG0840	transmembrane signaling receptor activity
AJS_RS01855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AJS_RS01860	COG0134	indole-3-glycerol-phosphate synthase activity
AJS_RS01865	COG3706	GGDEF domain
AJS_RS01870	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AJS_RS01880	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AJS_RS01890	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AJS_RS01900	COG0783	Belongs to the Dps family
AJS_RS01910	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AJS_RS01920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AJS_RS01930	COG3842	ATPase activity
AJS_RS01935	COG3842	ATPase activity
AJS_RS01945	COG0395	ABC-type sugar transport system, permease component
AJS_RS01960	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AJS_RS01965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AJS_RS01970	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AJS_RS01975	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AJS_RS01980	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AJS_RS01985	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AJS_RS01990	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AJS_RS01995	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AJS_RS02000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AJS_RS02005	COG1841	ribosomal large subunit assembly
AJS_RS02010	COG0200	Binds to the 23S rRNA
AJS_RS02015	COG0201	protein transport
AJS_RS02020	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AJS_RS02025	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AJS_RS02030	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AJS_RS02035	COG0202	RNA polymerase activity
AJS_RS02040	COG0203	ribosomal protein L17
AJS_RS02060	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AJS_RS02065	COG0463	Glycosyl transferase, family 2
AJS_RS02080	COG0792	nuclease activity
AJS_RS02085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AJS_RS02090	COG2823	Periplasmic or secreted lipoprotein
AJS_RS02095	COG2084	Dehydrogenase
AJS_RS02105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AJS_RS02125	COG2733	membrane
AJS_RS02135	COG0277	FAD linked oxidase domain protein
AJS_RS02165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AJS_RS02170	COG3850	Histidine kinase
AJS_RS02175	COG2197	response regulator
AJS_RS02185	COG2223	nitrite transmembrane transporter activity
AJS_RS02190	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AJS_RS02195	COG1140	nitrate reductase beta subunit
AJS_RS02200	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
AJS_RS02205	COG2181	nitrate reductase activity
AJS_RS02235	COG3945	hemerythrin HHE cation binding domain
AJS_RS02265	COG0243	molybdopterin cofactor binding
AJS_RS02275	COG1473	amidohydrolase
AJS_RS02295	COG2818	Glycosylase
AJS_RS02305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AJS_RS02355	COG1022	Amp-dependent synthetase and ligase
AJS_RS02360	COG3267	Type II secretory pathway component ExeA
AJS_RS02360	COG3409	Peptidoglycan-binding domain 1 protein
AJS_RS02370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AJS_RS02375	COG1187	pseudouridine synthase activity
AJS_RS02380	COG0326	Molecular chaperone. Has ATPase activity
AJS_RS02385	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS02415	COG1764	response to oxidative stress
AJS_RS02420	COG1846	Transcriptional regulator
AJS_RS02475	COG0037	tRNA processing
AJS_RS02495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AJS_RS02510	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AJS_RS02515	COG3387	PFAM Glycoside hydrolase 15-related
AJS_RS02520	COG1877	trehalose-phosphatase activity
AJS_RS02530	COG0617	tRNA 3'-terminal CCA addition
AJS_RS02545	COG0625	glutathione transferase activity
AJS_RS02550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AJS_RS02570	COG3128	pkhd-type hydroxylase
AJS_RS02580	COG4774	siderophore transport
AJS_RS02585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AJS_RS02590	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS02600	COG3186	Phenylalanine-4-hydroxylase
AJS_RS02615	COG1522	sequence-specific DNA binding
AJS_RS02625	COG4535	Mg2 and Co2 transporter CorC
AJS_RS02630	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AJS_RS02645	COG0752	glycyl-tRNA synthetase alpha subunit
AJS_RS02650	COG0751	glycine-tRNA ligase activity
AJS_RS02655	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AJS_RS02660	COG0204	Acyl-transferase
AJS_RS02675	COG1652	LysM domain
AJS_RS02680	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AJS_RS02790	COG1215	transferase activity, transferring glycosyl groups
AJS_RS02840	COG5654	RES domain protein
AJS_RS02865	COG4372	Transposase
AJS_RS02870	COG0582	viral genome integration into host DNA
AJS_RS02895	COG0438	transferase activity, transferring glycosyl groups
AJS_RS02940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AJS_RS02945	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AJS_RS02950	COG1309	transcriptional regulator
AJS_RS02955	COG3039	Transposase
AJS_RS02965	COG1960	acyl-CoA dehydrogenase activity
AJS_RS02975	COG1250	3-hydroxyacyl-CoA dehydrogenase
AJS_RS02975	COG1024	Enoyl-CoA hydratase
AJS_RS02980	COG0183	Belongs to the thiolase family
AJS_RS02995	COG1024	Enoyl-CoA hydratase
AJS_RS03010	COG1607	acyl-coa hydrolase
AJS_RS03015	COG5265	(ABC) transporter
AJS_RS03025	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AJS_RS03030	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AJS_RS03030	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AJS_RS03035	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AJS_RS03040	COG0583	DNA-binding transcription factor activity
AJS_RS03050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AJS_RS03055	COG0765	amino acid transport
AJS_RS03060	COG0765	amino acid transport
AJS_RS03065	COG1126	abc transporter atp-binding protein
AJS_RS03070	COG2423	ornithine cyclodeaminase activity
AJS_RS03075	COG1522	sequence-specific DNA binding
AJS_RS03080	COG2010	Cytochrome c
AJS_RS03090	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AJS_RS03095	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AJS_RS03105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AJS_RS03115	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AJS_RS03120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AJS_RS03130	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AJS_RS03135	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AJS_RS03150	COG0316	Belongs to the HesB IscA family
AJS_RS03155	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AJS_RS03165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AJS_RS03175	COG0583	DNA-binding transcription factor activity
AJS_RS03185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AJS_RS03190	COG4251	negative regulation of phosphorylation
AJS_RS03205	COG1522	sequence-specific DNA binding
AJS_RS03230	COG1064	alcohol dehydrogenase
AJS_RS03235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AJS_RS03240	COG0784	Response regulator, receiver
AJS_RS03240	COG5002	protein histidine kinase activity
AJS_RS03240	COG2198	Histidine kinase
AJS_RS03245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AJS_RS03255	COG2205	protein histidine kinase activity
AJS_RS03270	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS03275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AJS_RS03280	COG3045	CreA protein
AJS_RS03285	COG0189	ligase activity
AJS_RS03285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AJS_RS03290	COG0189	ligase activity
AJS_RS03290	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AJS_RS03295	COG1132	(ABC) transporter
AJS_RS03325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AJS_RS03395	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AJS_RS03400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AJS_RS03405	COG1765	OsmC-like protein
AJS_RS03410	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AJS_RS03430	COG4166	transmembrane transport
AJS_RS03440	COG1473	amidohydrolase
AJS_RS03450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AJS_RS03455	COG0444	Belongs to the ABC transporter superfamily
AJS_RS03460	COG4608	Belongs to the ABC transporter superfamily
AJS_RS03465	COG0737	Belongs to the 5'-nucleotidase family
AJS_RS03470	COG1881	PFAM PEBP family protein
AJS_RS03480	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AJS_RS03485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AJS_RS03490	COG0166	Belongs to the GPI family
AJS_RS03500	COG0459	protein refolding
AJS_RS03505	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AJS_RS03510	COG1056	cytidyltransferase-related domain
AJS_RS03510	COG1051	belongs to the nudix hydrolase family
AJS_RS03525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AJS_RS03535	COG1560	Kdo2-lipid A biosynthetic process
AJS_RS03545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AJS_RS03555	COG1333	cytochrome c biogenesis protein
AJS_RS03560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AJS_RS03565	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AJS_RS03570	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AJS_RS03635	COG1965	Belongs to the frataxin family
AJS_RS03670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AJS_RS03675	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AJS_RS03700	COG0070	glutamate synthase
AJS_RS03700	COG0067	glutamate synthase
AJS_RS03700	COG0069	glutamate synthase activity
AJS_RS03715	COG0765	amino acid transport
AJS_RS03725	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AJS_RS03730	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AJS_RS03735	COG1127	ABC transporter
AJS_RS03740	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AJS_RS03745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AJS_RS03770	COG1131	(ABC) transporter
AJS_RS03775	COG0842	Transport permease protein
AJS_RS03780	COG5007	Belongs to the BolA IbaG family
AJS_RS03785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AJS_RS03790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AJS_RS03795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AJS_RS03805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AJS_RS03810	COG0131	Imidazoleglycerol-phosphate dehydratase
AJS_RS03820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AJS_RS03835	COG0438	transferase activity, transferring glycosyl groups
AJS_RS03865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AJS_RS03870	COG0107	imidazoleglycerol-phosphate synthase activity
AJS_RS03875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AJS_RS03880	COG0140	phosphoribosyl-ATP diphosphatase activity
AJS_RS03895	COG0537	adenosine 5'-monophosphoramidase activity
AJS_RS03900	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AJS_RS03905	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AJS_RS03910	COG0805	protein transport
AJS_RS03915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AJS_RS03925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AJS_RS03930	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AJS_RS03935	COG1970	mechanosensitive ion channel activity
AJS_RS03940	COG0723	plastoquinol--plastocyanin reductase activity
AJS_RS03945	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AJS_RS03950	COG2857	Cytochrome c1
AJS_RS03955	COG0625	glutathione transferase activity
AJS_RS03960	COG2969	positive regulation of protein catabolic process
AJS_RS03975	COG0739	heme binding
AJS_RS03980	COG0653	protein targeting
AJS_RS03985	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AJS_RS03995	COG0494	nUDIX hydrolase
AJS_RS04000	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AJS_RS04005	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AJS_RS04010	COG0237	dephospho-CoA kinase activity
AJS_RS04080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AJS_RS04110	COG2129	metallophosphoesterase
AJS_RS04145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AJS_RS04150	COG1111	helicase
AJS_RS04150	COG1205	dead DEAH box helicase
AJS_RS04165	COG4584	PFAM Integrase catalytic
AJS_RS04185	COG0142	geranyltranstransferase activity
AJS_RS04190	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AJS_RS04195	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AJS_RS04200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AJS_RS04205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AJS_RS04210	COG0494	nUDIX hydrolase
AJS_RS04215	COG0442	prolyl-tRNA aminoacylation
AJS_RS04220	COG0741	lytic transglycosylase activity
AJS_RS04225	COG1253	flavin adenine dinucleotide binding
AJS_RS04230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AJS_RS04240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AJS_RS04245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AJS_RS04255	COG0583	DNA-binding transcription factor activity
AJS_RS04270	COG1511	domain protein
AJS_RS04270	COG3264	Mechanosensitive ion channel
AJS_RS04275	COG0584	glycerophosphoryl diester phosphodiesterase
AJS_RS04280	COG3842	ATPase activity
AJS_RS04285	COG0395	ABC-type sugar transport system, permease component
AJS_RS04290	COG1175	transmembrane transport
AJS_RS04295	COG1653	transport
AJS_RS04300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AJS_RS04320	COG2226	methyltransferase
AJS_RS04335	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AJS_RS04355	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AJS_RS04375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AJS_RS04380	COG0302	gtp cyclohydrolase
AJS_RS04415	COG1280	lysine exporter protein (LysE YggA)
AJS_RS04420	COG0154	amidase activity
AJS_RS04430	COG4608	Belongs to the ABC transporter superfamily
AJS_RS04435	COG0444	Belongs to the ABC transporter superfamily
AJS_RS04440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AJS_RS04450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AJS_RS04455	COG0193	aminoacyl-tRNA hydrolase activity
AJS_RS04460	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AJS_RS04465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AJS_RS04475	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AJS_RS04490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AJS_RS04505	COG1660	Displays ATPase and GTPase activities
AJS_RS04510	COG0497	DNA recombination
AJS_RS04515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AJS_RS04520	COG1420	regulation of RNA biosynthetic process
AJS_RS04565	COG3328	transposase activity
AJS_RS04600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AJS_RS04605	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AJS_RS04625	COG1561	YicC-like family, N-terminal region
AJS_RS04630	COG0582	viral genome integration into host DNA
AJS_RS04655	COG0305	Participates in initiation and elongation during chromosome replication
AJS_RS04660	COG1396	sequence-specific DNA binding
AJS_RS04740	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AJS_RS04750	COG0194	GDP metabolic process
AJS_RS04755	COG1758	RNA polymerase activity
AJS_RS04760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AJS_RS04780	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AJS_RS04785	COG1185	polyribonucleotide nucleotidyltransferase activity
AJS_RS04790	COG3321	synthase
AJS_RS04790	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS04790	COG0604	alcohol dehydrogenase
AJS_RS04795	COG0149	triose-phosphate isomerase activity
AJS_RS04810	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AJS_RS04815	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AJS_RS04820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AJS_RS04825	COG0649	NAD binding
AJS_RS04840	COG1034	ATP synthesis coupled electron transport
AJS_RS04845	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AJS_RS04850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AJS_RS04860	COG0713	ATP synthesis coupled electron transport
AJS_RS04875	COG1007	ATP synthesis coupled electron transport
AJS_RS04890	COG1132	(ABC) transporter
AJS_RS04900	COG4133	protoheme IX ABC transporter activity
AJS_RS04905	COG1280	lysine exporter protein (LysE YggA)
AJS_RS04915	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AJS_RS04925	COG0586	Pfam SNARE associated Golgi protein
AJS_RS04940	COG0860	N-Acetylmuramoyl-L-alanine amidase
AJS_RS04945	COG0802	atpase or kinase
AJS_RS04950	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AJS_RS04960	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS04965	COG4974	Belongs to the 'phage' integrase family
AJS_RS04975	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AJS_RS04980	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AJS_RS04985	COG2833	Protein of unknown function (DUF455)
AJS_RS04995	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AJS_RS05005	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AJS_RS05010	COG0148	phosphopyruvate hydratase activity
AJS_RS05020	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AJS_RS05025	COG0504	CTP synthase activity
AJS_RS05030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AJS_RS05035	COG0756	dUTP diphosphatase activity
AJS_RS05045	COG1047	Peptidyl-prolyl cis-trans
AJS_RS05050	COG2850	peptidyl-arginine hydroxylation
AJS_RS05065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AJS_RS05070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AJS_RS05075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AJS_RS05085	COG2814	Major facilitator Superfamily
AJS_RS05095	COG0741	lytic transglycosylase activity
AJS_RS05105	COG0840	transmembrane signaling receptor activity
AJS_RS05120	COG2308	Evidence 4 Homologs of previously reported genes of
AJS_RS05135	COG4628	conserved protein (DUF2132)
AJS_RS05155	COG4774	siderophore transport
AJS_RS05200	COG1722	exodeoxyribonuclease VII activity
AJS_RS05205	COG0142	geranyltranstransferase activity
AJS_RS05210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AJS_RS05215	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AJS_RS05220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AJS_RS05230	COG0405	Gamma-glutamyltransferase
AJS_RS05245	COG0483	inositol monophosphate 1-phosphatase activity
AJS_RS05255	COG1045	serine acetyltransferase
AJS_RS05265	COG1063	alcohol dehydrogenase
AJS_RS05275	COG0521	Mo-molybdopterin cofactor biosynthetic process
AJS_RS05280	COG3028	Belongs to the UPF0307 family
AJS_RS05285	COG0312	modulator of DNA gyrase
AJS_RS05305	COG0114	fumarate hydratase activity
AJS_RS05315	COG0745	RESPONSE REGULATOR receiver
AJS_RS05320	COG2205	protein histidine kinase activity
AJS_RS05340	COG4176	ABC-type proline glycine betaine transport system permease component
AJS_RS05345	COG4175	Glycine betaine
AJS_RS05355	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AJS_RS05365	COG4654	Cytochrome c, class I
AJS_RS05375	COG0129	dihydroxy-acid dehydratase activity
AJS_RS05380	COG0129	dihydroxy-acid dehydratase activity
AJS_RS05395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AJS_RS05400	COG1802	Transcriptional regulator
AJS_RS05420	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS05440	COG3278	Belongs to the heme-copper respiratory oxidase family
AJS_RS05475	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AJS_RS05480	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AJS_RS05500	COG4206	TonB-dependent receptor
AJS_RS05505	COG1797	cobyrinic acid a,c-diamide synthase activity
AJS_RS05515	COG4607	ABC-type enterochelin transport system periplasmic component
AJS_RS05520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AJS_RS05525	COG1120	ATPase activity
AJS_RS05530	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
AJS_RS05560	COG3328	transposase activity
AJS_RS05570	COG2814	Major facilitator Superfamily
AJS_RS05585	COG0280	phosphate acetyltransferase
AJS_RS05585	COG0281	malic enzyme
AJS_RS05590	COG2233	PERMEase
AJS_RS05615	COG2186	Transcriptional regulator
AJS_RS05655	COG1012	belongs to the aldehyde dehydrogenase family
AJS_RS05670	COG0402	S-adenosylhomocysteine deaminase activity
AJS_RS05675	COG0717	Belongs to the dCTP deaminase family
AJS_RS05680	COG2321	neutral zinc metallopeptidase
AJS_RS05685	COG0513	Belongs to the DEAD box helicase family
AJS_RS05700	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
AJS_RS05715	COG0348	domain, Protein
AJS_RS05715	COG3901	Regulator of nitric oxide reductase transcription
AJS_RS05720	COG4263	nitrous-oxide reductase activity
AJS_RS05730	COG3245	cytochrome
AJS_RS05740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AJS_RS05745	COG2916	Histone family protein nucleoid-structuring protein H-NS
AJS_RS05750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AJS_RS05765	COG3279	Response regulator of the LytR AlgR family
AJS_RS05775	COG3275	phosphorelay sensor kinase activity
AJS_RS05785	COG1968	undecaprenyl-diphosphatase activity
AJS_RS05795	COG2267	carboxylic ester hydrolase activity
AJS_RS05810	COG3540	Alkaline phosphatase
AJS_RS05825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AJS_RS05830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AJS_RS05840	COG0564	pseudouridine synthase activity
AJS_RS05845	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AJS_RS05850	COG1187	pseudouridine synthase activity
AJS_RS05855	COG0105	UTP biosynthetic process
AJS_RS05860	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AJS_RS05880	COG0124	histidyl-tRNA synthetase
AJS_RS05895	COG1160	GTP binding
AJS_RS05900	COG1923	regulation of RNA biosynthetic process
AJS_RS05905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AJS_RS05910	COG0330	HflC and HflK could
AJS_RS05915	COG0330	HflC and HflK could
AJS_RS05925	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AJS_RS05930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AJS_RS05965	COG1187	pseudouridine synthase activity
AJS_RS05975	COG0726	polysaccharide deacetylase
AJS_RS05995	COG0174	glutamine synthetase
AJS_RS06010	COG2204	response regulator
AJS_RS06020	COG0708	Exodeoxyribonuclease III
AJS_RS06030	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AJS_RS06035	COG0277	FAD linked oxidase domain protein
AJS_RS06045	COG1295	ribonuclease BN
AJS_RS06050	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AJS_RS06055	COG1562	ergosterol biosynthetic process
AJS_RS06080	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AJS_RS06090	COG0544	peptidyl-prolyl cis-trans isomerase activity
AJS_RS06095	COG0740	serine-type endopeptidase activity
AJS_RS06100	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AJS_RS06105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AJS_RS06115	COG0582	viral genome integration into host DNA
AJS_RS06130	COG1484	DNA-dependent DNA replication
AJS_RS06185	COG3328	transposase activity
AJS_RS06200	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AJS_RS06215	COG2132	Multicopper oxidase
AJS_RS06220	COG0745	RESPONSE REGULATOR receiver
AJS_RS06305	COG2003	Belongs to the UPF0758 family
AJS_RS06360	COG3311	Transcriptional regulator
AJS_RS06365	COG1569	PIN domain
AJS_RS06445	COG0798	PFAM Bile acid sodium symporter
AJS_RS06450	COG1393	Belongs to the ArsC family
AJS_RS06455	COG0431	NADPH-dependent FMN reductase
AJS_RS06545	COG0789	Transcriptional regulator
AJS_RS06585	COG0270	DNA (cytosine-5-)-methyltransferase activity
AJS_RS06590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AJS_RS06595	COG0629	single-stranded DNA binding
AJS_RS06655	COG3609	addiction module antidote protein, CC2985 family
AJS_RS06665	COG1742	UPF0060 membrane protein
AJS_RS06715	COG0789	Transcriptional regulator
AJS_RS06720	COG4974	Belongs to the 'phage' integrase family
AJS_RS06740	COG0582	viral genome integration into host DNA
AJS_RS06750	COG4584	PFAM Integrase catalytic
AJS_RS06785	COG1396	sequence-specific DNA binding
AJS_RS06790	COG0583	DNA-binding transcription factor activity
AJS_RS06820	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AJS_RS06825	COG4232	protein-disulfide reductase activity
AJS_RS06830	COG0745	RESPONSE REGULATOR receiver
AJS_RS06840	COG0492	ferredoxin-NADP+ reductase activity
AJS_RS06865	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AJS_RS06875	COG1275	C4-dicarboxylate transporter malic acid transport protein
AJS_RS06890	COG1230	cation diffusion facilitator family transporter
AJS_RS06895	COG0640	Transcriptional regulator
AJS_RS06905	COG0789	Transcriptional regulator
AJS_RS06910	COG2814	Major facilitator Superfamily
AJS_RS06920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AJS_RS06945	COG3039	Transposase
AJS_RS06950	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AJS_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS06965	COG0583	DNA-binding transcription factor activity
AJS_RS07020	COG2003	Belongs to the UPF0758 family
AJS_RS07245	COG0270	DNA (cytosine-5-)-methyltransferase activity
AJS_RS07250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AJS_RS07255	COG0629	single-stranded DNA binding
AJS_RS07310	COG2963	transposase activity
AJS_RS07320	COG3039	Transposase
AJS_RS07325	COG2205	protein histidine kinase activity
AJS_RS07375	COG1742	UPF0060 membrane protein
AJS_RS07380	COG0789	Transcriptional regulator
AJS_RS07395	COG3174	membrane
AJS_RS07415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AJS_RS07425	COG1677	Flagellar hook-basal body complex protein FliE
AJS_RS07460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AJS_RS07470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AJS_RS07515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AJS_RS07525	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AJS_RS07530	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AJS_RS07540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AJS_RS07555	COG2217	Heavy metal translocating P-type atpase
AJS_RS07560	COG2326	polyphosphate kinase activity
AJS_RS07595	COG3039	Transposase
AJS_RS07600	COG4774	siderophore transport
AJS_RS07945	COG1475	DNA binding
AJS_RS08045	COG1840	ABC-type Fe3 transport system, periplasmic component
AJS_RS08050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AJS_RS08060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AJS_RS08075	COG3384	dioxygenase
AJS_RS08090	COG1522	sequence-specific DNA binding
AJS_RS08100	COG3228	Belongs to the MtfA family
AJS_RS08105	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AJS_RS08125	COG0215	cysteine-tRNA ligase activity
AJS_RS08145	COG0037	tRNA processing
AJS_RS08150	COG0527	aspartate kinase activity
AJS_RS08165	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AJS_RS08170	COG0583	DNA-binding transcription factor activity
AJS_RS08200	COG3800	Transcriptional regulator
AJS_RS08200	COG1396	sequence-specific DNA binding
AJS_RS08210	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AJS_RS08225	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS08270	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AJS_RS08275	COG1011	Hydrolase
AJS_RS08285	COG2267	carboxylic ester hydrolase activity
AJS_RS08300	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AJS_RS08305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AJS_RS08310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AJS_RS08315	COG0741	lytic transglycosylase activity
AJS_RS08330	COG1959	2 iron, 2 sulfur cluster binding
AJS_RS08345	COG0688	phosphatidylethanolamine metabolic process
AJS_RS08355	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AJS_RS08370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AJS_RS08380	COG2917	probably involved in intracellular septation
AJS_RS08385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AJS_RS08390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AJS_RS08395	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS08405	COG0559	Belongs to the binding-protein-dependent transport system permease family
AJS_RS08415	COG0411	ABC transporter
AJS_RS08430	COG0183	Belongs to the thiolase family
AJS_RS08440	COG1960	acyl-CoA dehydrogenase activity
AJS_RS08450	COG3639	organic phosphonate transmembrane transporter activity
AJS_RS08455	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AJS_RS08460	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AJS_RS08490	COG2130	NADP-dependent
AJS_RS08495	COG2153	protein acetylation
AJS_RS08515	COG2814	Major facilitator Superfamily
AJS_RS08520	COG2814	Major facilitator Superfamily
AJS_RS08540	COG2183	response to ionizing radiation
AJS_RS08580	COG0354	folic acid binding
AJS_RS08585	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AJS_RS08590	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AJS_RS08595	COG0470	DNA polymerase III
AJS_RS08605	COG0084	hydrolase, TatD family'
AJS_RS08615	COG1132	(ABC) transporter
AJS_RS08620	COG0823	Involved in the tonB-independent uptake of proteins
AJS_RS08630	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
AJS_RS08635	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AJS_RS08675	COG1484	DNA-dependent DNA replication
AJS_RS08680	COG4584	PFAM Integrase catalytic
AJS_RS08690	COG4584	PFAM Integrase catalytic
AJS_RS08705	COG3328	transposase activity
AJS_RS08710	COG0741	lytic transglycosylase activity
AJS_RS08710	COG1388	LysM domain
AJS_RS08715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AJS_RS08720	COG2226	methyltransferase
AJS_RS08725	COG0328	RNA-DNA hybrid ribonuclease activity
AJS_RS08740	COG0746	molybdenum cofactor guanylyltransferase activity
AJS_RS08745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AJS_RS08765	COG3039	Transposase
AJS_RS08790	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AJS_RS08795	COG0835	chemotaxis
AJS_RS08805	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AJS_RS08805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AJS_RS08810	COG0347	Belongs to the P(II) protein family
AJS_RS08840	COG1595	DNA-templated transcription, initiation
AJS_RS08845	COG0028	Belongs to the TPP enzyme family
AJS_RS08850	COG0440	acetolactate synthase activity
AJS_RS08855	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AJS_RS08860	COG1183	phosphatidylcholine synthase activity
AJS_RS08870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AJS_RS08880	COG1414	Transcriptional regulator
AJS_RS08900	COG1024	Enoyl-CoA hydratase
AJS_RS08905	COG1250	3-hydroxyacyl-CoA dehydrogenase
AJS_RS08920	COG2022	thiamine diphosphate biosynthetic process
AJS_RS08935	COG0351	phosphomethylpyrimidine kinase
AJS_RS08945	COG0492	ferredoxin-NADP+ reductase activity
AJS_RS08950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AJS_RS08955	COG2895	sulfate adenylyltransferase (ATP) activity
AJS_RS08960	COG0175	sulfate reduction
AJS_RS08965	COG0175	sulfate reduction
AJS_RS08980	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AJS_RS08980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AJS_RS08985	COG2860	membrane
AJS_RS08990	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AJS_RS08995	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AJS_RS09000	COG0625	glutathione transferase activity
AJS_RS09005	COG0415	Belongs to the DNA photolyase family
AJS_RS09050	COG4166	transmembrane transport
AJS_RS09055	COG4174	ABC transporter (Permease)
AJS_RS09060	COG4239	(ABC) transporter, permease
AJS_RS09065	COG4172	Belongs to the ABC transporter superfamily
AJS_RS09075	COG3622	Belongs to the hyi family
AJS_RS09080	COG0589	response to stress
AJS_RS09105	COG0628	permease
AJS_RS09110	COG0567	Dehydrogenase, E1 component
AJS_RS09115	COG0508	dehydrogenase complex catalyzes the overall conversion of
AJS_RS09120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AJS_RS09125	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AJS_RS09135	COG0631	protein serine/threonine phosphatase activity
AJS_RS09140	COG1199	ATP-dependent helicase activity
AJS_RS09155	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AJS_RS09160	COG0542	response to heat
AJS_RS09165	COG1309	transcriptional regulator
AJS_RS09180	COG1136	(ABC) transporter
AJS_RS09185	COG2951	lytic endotransglycosylase activity
AJS_RS09190	COG2925	Exonuclease
AJS_RS09200	COG3284	Transcriptional regulator
AJS_RS09210	COG4644	lycopene metabolic process
AJS_RS09215	COG0589	response to stress
AJS_RS09220	COG2801	Transposase and inactivated derivatives
AJS_RS09225	COG2963	transposase activity
AJS_RS09270	COG1484	DNA-dependent DNA replication
AJS_RS09275	COG4584	PFAM Integrase catalytic
AJS_RS09345	COG2323	membrane
AJS_RS09440	COG1012	belongs to the aldehyde dehydrogenase family
AJS_RS09445	COG1283	sodium-dependent phosphate transmembrane transporter activity
AJS_RS09450	COG0628	permease
AJS_RS09455	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AJS_RS09470	COG3604	Transcriptional regulator
AJS_RS09475	COG0433	COG0433 Predicted ATPase
AJS_RS09480	COG0217	transcriptional regulatory protein
AJS_RS09485	COG0151	Belongs to the GarS family
AJS_RS09490	COG0408	coproporphyrinogen oxidase activity
AJS_RS09495	COG0799	negative regulation of ribosome biogenesis
AJS_RS09500	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AJS_RS09505	COG0424	maF-like protein
AJS_RS09520	COG0535	radical SAM domain protein
AJS_RS09540	COG3391	amine dehydrogenase activity
AJS_RS09545	COG2010	Cytochrome c
AJS_RS09555	COG1648	precorrin-2 dehydrogenase activity
AJS_RS09555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AJS_RS09565	COG0436	Aminotransferase
AJS_RS09575	COG0583	DNA-binding transcription factor activity
AJS_RS09595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AJS_RS09615	COG0683	leucine binding
AJS_RS09620	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS09635	COG0589	response to stress
AJS_RS09645	COG0183	Belongs to the thiolase family
AJS_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS09665	COG0545	Peptidyl-prolyl cis-trans isomerase
AJS_RS09670	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AJS_RS09670	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AJS_RS09675	COG0509	glycine decarboxylation via glycine cleavage system
AJS_RS09680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AJS_RS09695	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AJS_RS09730	COG4120	Belongs to the binding-protein-dependent transport system permease family
AJS_RS09750	COG0642	Histidine kinase
AJS_RS09755	COG0745	RESPONSE REGULATOR receiver
AJS_RS09780	COG0753	catalase activity
AJS_RS09785	COG1252	NADH dehydrogenase
AJS_RS09805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AJS_RS09825	COG0587	DNA-directed DNA polymerase activity
AJS_RS09875	COG0582	viral genome integration into host DNA
AJS_RS09885	COG1012	belongs to the aldehyde dehydrogenase family
AJS_RS09890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AJS_RS09900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AJS_RS09905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AJS_RS09910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AJS_RS09910	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AJS_RS09915	COG0583	DNA-binding transcription factor activity
AJS_RS09920	COG1741	Belongs to the pirin family
AJS_RS09925	COG2259	Doxx family
AJS_RS09930	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AJS_RS09935	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AJS_RS09945	COG4948	Mandelate Racemase Muconate Lactonizing
AJS_RS09950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS09960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AJS_RS09970	COG2186	Transcriptional regulator
AJS_RS09975	COG4948	Mandelate Racemase Muconate Lactonizing
AJS_RS09985	COG2721	sulfolactate sulfo-lyase activity
AJS_RS09990	COG3386	PFAM SMP-30 Gluconolaconase
AJS_RS09995	COG3171	Protein conserved in bacteria
AJS_RS10000	COG0133	tryptophan synthase activity
AJS_RS10010	COG3039	Transposase
AJS_RS10025	COG1960	acyl-CoA dehydrogenase activity
AJS_RS10040	COG0583	DNA-binding transcription factor activity
AJS_RS10055	COG2133	pyrroloquinoline quinone binding
AJS_RS10100	COG1042	CoA-binding domain protein
AJS_RS10100	COG0045	succinate-CoA ligase (ADP-forming) activity
AJS_RS10100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AJS_RS10110	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AJS_RS10120	COG1054	Belongs to the UPF0176 family
AJS_RS10125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AJS_RS10130	COG1309	transcriptional regulator
AJS_RS10135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AJS_RS10175	COG1022	Amp-dependent synthetase and ligase
AJS_RS10180	COG1802	Transcriptional regulator
AJS_RS10185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AJS_RS10185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AJS_RS10190	COG1703	isobutyryl-CoA mutase activity
AJS_RS10195	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AJS_RS10200	COG4770	biotin carboxylase activity
AJS_RS10210	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AJS_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS10220	COG0346	lactoylglutathione lyase activity
AJS_RS10225	COG0800	Aldolase
AJS_RS10235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
AJS_RS10240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AJS_RS10245	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AJS_RS10250	COG3265	gluconokinase activity
AJS_RS10255	COG1609	Transcriptional regulator
AJS_RS10270	COG2032	superoxide dismutase activity
AJS_RS10275	COG0259	pyridoxamine-phosphate oxidase activity
AJS_RS10305	COG2878	Part of a membrane complex involved in electron transport
AJS_RS10320	COG2171	N-acyltransferase activity
AJS_RS10330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AJS_RS10335	COG2890	protein-(glutamine-N5) methyltransferase activity
AJS_RS10340	COG0488	(ABC) transporter
AJS_RS10345	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS10350	COG0183	Belongs to the thiolase family
AJS_RS10355	COG3243	poly(R)-hydroxyalkanoic acid synthase
AJS_RS10395	COG1752	Esterase of the alpha-beta hydrolase superfamily
AJS_RS10400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AJS_RS10415	COG1196	nuclear chromosome segregation
AJS_RS10420	COG1742	UPF0060 membrane protein
AJS_RS10430	COG1132	(ABC) transporter
AJS_RS10435	COG2814	Major facilitator Superfamily
AJS_RS10440	COG0791	NLP P60 protein
AJS_RS10455	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AJS_RS10465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AJS_RS10500	COG0477	Major facilitator Superfamily
AJS_RS10510	COG1285	pathogenesis
AJS_RS10515	COG1024	Enoyl-CoA hydratase
AJS_RS10525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AJS_RS10530	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AJS_RS10535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AJS_RS10550	COG0765	amino acid transport
AJS_RS10580	COG1959	2 iron, 2 sulfur cluster binding
AJS_RS10595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AJS_RS10600	COG0508	dehydrogenase complex catalyzes the overall conversion of
AJS_RS10605	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AJS_RS10615	COG4566	intracellular signal transduction
AJS_RS10620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AJS_RS10635	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AJS_RS10640	COG0167	dihydroorotate dehydrogenase activity
AJS_RS10660	COG0579	oxidoreductase
AJS_RS10685	COG0633	Ferredoxin
AJS_RS10690	COG0443	Heat shock 70 kDa protein
AJS_RS10705	COG0822	iron-sulfur transferase activity
AJS_RS10710	COG1104	cysteine desulfurase activity
AJS_RS10715	COG1959	2 iron, 2 sulfur cluster binding
AJS_RS10740	COG0556	nucleotide-excision repair
AJS_RS10750	COG0840	transmembrane signaling receptor activity
AJS_RS10755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS10775	COG2826	transposase and inactivated derivatives, IS30 family
AJS_RS10805	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS10810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AJS_RS10810	COG0574	Belongs to the PEP-utilizing enzyme family
AJS_RS10905	COG2003	Belongs to the UPF0758 family
AJS_RS10975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AJS_RS11055	COG1396	sequence-specific DNA binding
AJS_RS11145	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AJS_RS11175	COG3077	Addiction module antitoxin, RelB DinJ family
AJS_RS11200	COG1739	Uncharacterized protein family UPF0029
AJS_RS11205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AJS_RS11220	COG0154	amidase activity
AJS_RS11230	COG3048	D-serine ammonia-lyase activity
AJS_RS11235	COG0583	DNA-binding transcription factor activity
AJS_RS11245	COG3550	peptidyl-serine autophosphorylation
AJS_RS11250	COG0583	DNA-binding transcription factor activity
AJS_RS11270	COG0179	Fumarylacetoacetate (FAA) hydrolase
AJS_RS11285	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AJS_RS11290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AJS_RS11300	COG5507	3-demethylubiquinone-9 3-methyltransferase
AJS_RS11320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AJS_RS11325	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AJS_RS11330	COG4181	ATPase activity
AJS_RS11345	COG0626	cystathionine gamma-synthase activity
AJS_RS11370	COG1741	Belongs to the pirin family
AJS_RS11385	COG1619	proteins homologs of microcin C7 resistance protein MccF
AJS_RS11400	COG0786	glutamate:sodium symporter activity
AJS_RS11405	COG0826	peptidase U32
AJS_RS11415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AJS_RS11420	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AJS_RS11425	COG3047	cAMP biosynthetic process
AJS_RS11430	COG2354	Protein conserved in bacteria
AJS_RS11440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AJS_RS11440	COG0047	phosphoribosylformylglycinamidine synthase activity
AJS_RS11455	COG0242	peptide deformylase activity
AJS_RS11460	COG2832	Protein of unknown function (DUF454)
AJS_RS11495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AJS_RS11500	COG1570	exodeoxyribonuclease VII activity
AJS_RS11505	COG0811	peptide transport
AJS_RS11510	COG0848	biopolymer transport protein
AJS_RS11515	COG1663	tetraacyldisaccharide 4'-kinase activity
AJS_RS11520	COG2835	tetraacyldisaccharide 4'-kinase activity
AJS_RS11525	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AJS_RS11530	COG0563	adenylate kinase activity
AJS_RS11535	COG0252	asparaginase activity
AJS_RS11540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AJS_RS11555	COG1643	Atp-dependent helicase
AJS_RS11565	COG1408	metallophosphoesterase
AJS_RS11580	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS11585	COG1268	BioY protein
AJS_RS11595	COG1122	ATPase activity
AJS_RS11600	COG2814	Major facilitator Superfamily
AJS_RS11615	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS11620	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AJS_RS11620	COG2755	lipolytic protein G-D-S-L family
AJS_RS11625	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AJS_RS11625	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AJS_RS11660	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AJS_RS11665	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AJS_RS11670	COG4208	sulfate ABC transporter
AJS_RS11675	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AJS_RS11680	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AJS_RS11690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AJS_RS11700	COG1464	Belongs to the NlpA lipoprotein family
AJS_RS11710	COG2011	ABC-type metal ion transport system permease component
AJS_RS11715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AJS_RS11730	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AJS_RS11735	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AJS_RS11740	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AJS_RS11755	COG0492	ferredoxin-NADP+ reductase activity
AJS_RS11760	COG2226	methyltransferase
AJS_RS11765	COG1074	ATP-dependent DNA helicase activity
AJS_RS11780	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AJS_RS11790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AJS_RS11795	COG1129	ABC transporter
AJS_RS11795	COG0842	Transport permease protein
AJS_RS11800	COG0842	Transport permease protein
AJS_RS11805	COG0254	rRNA binding
AJS_RS11815	COG0534	Mate efflux family protein
AJS_RS11825	COG0745	RESPONSE REGULATOR receiver
AJS_RS11830	COG0704	Plays a role in the regulation of phosphate uptake
AJS_RS11835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AJS_RS11840	COG0581	inorganic phosphate transmembrane transporter activity
AJS_RS11845	COG0573	inorganic phosphate transmembrane transporter activity
AJS_RS11850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AJS_RS11855	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AJS_RS11880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AJS_RS11895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AJS_RS11905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AJS_RS11910	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AJS_RS11915	COG1534	Rna-binding protein
AJS_RS11935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AJS_RS11940	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AJS_RS11950	COG0505	Belongs to the CarA family
AJS_RS11960	COG0789	Transcriptional regulator
AJS_RS11965	COG0776	regulation of translation
AJS_RS11970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AJS_RS11970	COG0072	phenylalanine-tRNA ligase activity
AJS_RS11975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AJS_RS11980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AJS_RS11985	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AJS_RS11990	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AJS_RS11995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AJS_RS12010	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AJS_RS12045	COG3193	protein, possibly involved in utilization of glycolate and propanediol
AJS_RS12050	COG0670	Belongs to the BI1 family
AJS_RS12060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AJS_RS12145	COG0642	Histidine kinase
AJS_RS12150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AJS_RS12160	COG0640	Transcriptional regulator
AJS_RS12195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AJS_RS12200	COG4584	PFAM Integrase catalytic
AJS_RS12210	COG5377	YqaJ viral recombinase family
AJS_RS12235	COG4372	Transposase
AJS_RS12260	COG0582	viral genome integration into host DNA
AJS_RS12270	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AJS_RS12285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AJS_RS12290	COG0077	Prephenate dehydratase
AJS_RS12290	COG1605	Chorismate mutase
AJS_RS12295	COG0287	Prephenate dehydrogenase
AJS_RS12300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AJS_RS12310	COG0776	regulation of translation
AJS_RS12320	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AJS_RS12330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AJS_RS12330	COG2111	Na H antiporter
AJS_RS12335	COG1006	Multisubunit Na H antiporter MnhC subunit
AJS_RS12340	COG0651	ATP synthesis coupled electron transport
AJS_RS12350	COG2212	antiporter activity
AJS_RS12390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AJS_RS12395	COG1611	Belongs to the LOG family
AJS_RS12410	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS12420	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AJS_RS12485	COG0564	pseudouridine synthase activity
AJS_RS12490	COG1285	pathogenesis
AJS_RS12510	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AJS_RS12545	COG0798	PFAM Bile acid sodium symporter
AJS_RS12555	COG0583	DNA-binding transcription factor activity
AJS_RS12565	COG2918	glutathione biosynthetic process
AJS_RS12570	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS12595	COG1196	nuclear chromosome segregation
AJS_RS12600	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AJS_RS12605	COG1061	Type III restriction enzyme res subunit
AJS_RS12610	COG1002	Type II restriction enzyme, methylase subunits
AJS_RS12690	COG0582	viral genome integration into host DNA
AJS_RS12695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AJS_RS12695	COG0519	Catalyzes the synthesis of GMP from XMP
AJS_RS12715	COG2867	negative regulation of translational initiation
AJS_RS12720	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AJS_RS12740	COG1024	Enoyl-CoA hydratase
AJS_RS12755	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AJS_RS12760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AJS_RS12765	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AJS_RS12770	COG0195	Participates in both transcription termination and antitermination
AJS_RS12775	COG0779	Required for maturation of 30S ribosomal subunits
AJS_RS12785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AJS_RS12785	COG2010	Cytochrome c
AJS_RS12800	COG0557	exoribonuclease II activity
AJS_RS12820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AJS_RS12825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AJS_RS12830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AJS_RS12835	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AJS_RS12840	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AJS_RS12845	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AJS_RS12860	COG0750	zinc metalloprotease
AJS_RS12865	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AJS_RS12870	COG0575	Belongs to the CDS family
AJS_RS12875	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AJS_RS12880	COG0233	cytoplasmic translational termination
AJS_RS12885	COG0528	UMP kinase activity
AJS_RS12890	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AJS_RS12895	COG0052	Belongs to the universal ribosomal protein uS2 family
AJS_RS12910	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AJS_RS12930	COG0789	Transcriptional regulator
AJS_RS12965	COG2132	Multicopper oxidase
AJS_RS12990	COG3191	aminopeptidase activity
AJS_RS13005	COG0488	(ABC) transporter
AJS_RS13010	COG0513	Belongs to the DEAD box helicase family
AJS_RS13040	COG0732	type I restriction modification DNA specificity domain
AJS_RS13075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AJS_RS13095	COG0322	excinuclease ABC activity
AJS_RS13145	COG2003	Belongs to the UPF0758 family
AJS_RS13160	COG1475	DNA binding
AJS_RS13170	COG5489	Protein of unknown function (DUF736)
AJS_RS13235	COG4959	Type IV secretory pathway protease TraF
AJS_RS13260	COG3328	transposase activity
AJS_RS13305	COG1677	Flagellar hook-basal body complex protein FliE
AJS_RS13310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AJS_RS13315	COG0789	Transcriptional regulator
AJS_RS13320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AJS_RS13330	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AJS_RS13350	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS13355	COG2226	methyltransferase
AJS_RS13380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AJS_RS13385	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AJS_RS13390	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AJS_RS13395	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AJS_RS13405	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AJS_RS13425	COG2326	polyphosphate kinase activity
AJS_RS13475	COG3174	membrane
AJS_RS13500	COG2217	Heavy metal translocating P-type atpase
AJS_RS13530	COG3039	Transposase
AJS_RS13570	COG2205	protein histidine kinase activity
AJS_RS13595	COG3328	transposase activity
AJS_RS13620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AJS_RS13635	COG1286	toxin biosynthetic process
AJS_RS13645	COG0285	dihydrofolate synthase activity
AJS_RS13650	COG1393	Belongs to the ArsC family
AJS_RS13660	COG3123	guanosine phosphorylase activity
AJS_RS13665	COG0137	argininosuccinate synthase activity
AJS_RS13670	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AJS_RS13675	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AJS_RS13680	COG1595	DNA-templated transcription, initiation
AJS_RS13685	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AJS_RS13690	COG0471	metal ion transport
AJS_RS13700	COG1666	GTP binding
AJS_RS13705	COG3577	Aspartyl protease
AJS_RS13715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AJS_RS13725	COG0667	Aldo Keto reductase
AJS_RS13740	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AJS_RS13745	COG0308	aminopeptidase N
AJS_RS13750	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AJS_RS13760	COG1793	dna ligase
AJS_RS13790	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AJS_RS13795	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AJS_RS13800	COG0436	Aminotransferase
AJS_RS13805	COG0824	Thioesterase
AJS_RS13825	COG0477	Major facilitator Superfamily
AJS_RS13835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AJS_RS13840	COG1845	cytochrome c oxidase, subunit III
AJS_RS13845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AJS_RS13860	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AJS_RS13870	COG0826	peptidase U32
AJS_RS13905	COG4106	trans-aconitate 2-methyltransferase activity
AJS_RS13910	COG0039	L-malate dehydrogenase activity
AJS_RS13915	COG2188	Transcriptional regulator
AJS_RS13930	COG1053	succinate dehydrogenase
AJS_RS13935	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AJS_RS13940	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AJS_RS13945	COG0372	Belongs to the citrate synthase family
AJS_RS13955	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AJS_RS13960	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AJS_RS13980	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AJS_RS13995	COG1960	acyl-CoA dehydrogenase activity
AJS_RS14010	COG1511	domain protein
AJS_RS14010	COG3264	Mechanosensitive ion channel
AJS_RS14020	COG0123	including yeast histone deacetylase and acetoin utilization protein
AJS_RS14025	COG0714	Associated with various cellular activities
AJS_RS14040	COG2951	lytic endotransglycosylase activity
AJS_RS14045	COG0583	DNA-binding transcription factor activity
AJS_RS14055	COG0683	leucine binding
AJS_RS14070	COG0577	efflux transmembrane transporter activity
AJS_RS14070	COG1136	(ABC) transporter
AJS_RS14075	COG1136	(ABC) transporter
AJS_RS14075	COG0577	efflux transmembrane transporter activity
AJS_RS14080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AJS_RS14085	COG1538	Outer membrane efflux protein
AJS_RS14090	COG1012	belongs to the aldehyde dehydrogenase family
AJS_RS14095	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AJS_RS14110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AJS_RS14115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AJS_RS14120	COG1116	anion transmembrane transporter activity
AJS_RS14125	COG0516	GMP reductase activity
AJS_RS14125	COG0517	IMP dehydrogenase activity
AJS_RS14140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AJS_RS14145	COG1538	Outer membrane efflux protein
AJS_RS14150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AJS_RS14155	COG2146	nitrite reductase [NAD(P)H] activity
AJS_RS14160	COG0243	molybdopterin cofactor binding
AJS_RS14165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AJS_RS14175	COG1607	acyl-coa hydrolase
AJS_RS14185	COG2081	HI0933 family
AJS_RS14205	COG0822	iron-sulfur transferase activity
AJS_RS14210	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AJS_RS14220	COG0396	ATPase activity
AJS_RS14225	COG0719	Fe-S assembly protein
AJS_RS14230	COG0640	Transcriptional regulator
AJS_RS14245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AJS_RS14250	COG1610	YqeY-like protein
AJS_RS14255	COG0473	3-isopropylmalate dehydrogenase activity
AJS_RS14265	COG1230	cation diffusion facilitator family transporter
AJS_RS14290	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AJS_RS14295	COG1451	nucleotide metabolic process
AJS_RS14310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AJS_RS14315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS14320	COG0583	DNA-binding transcription factor activity
AJS_RS14330	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AJS_RS14340	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AJS_RS14355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AJS_RS14395	COG1289	transmembrane transporter activity
AJS_RS14400	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AJS_RS14405	COG0181	hydroxymethylbilane synthase activity
AJS_RS14435	COG0525	valine-tRNA ligase activity
AJS_RS14445	COG0425	Belongs to the sulfur carrier protein TusA family
AJS_RS14450	COG2816	NAD+ diphosphatase activity
AJS_RS14480	COG3846	protein secretion by the type IV secretion system
AJS_RS14495	COG3451	type IV secretory pathway VirB4
AJS_RS14505	COG3838	Conjugal transfer protein Trbc
AJS_RS14510	COG4962	Type ii secretion system protein e
AJS_RS14530	COG4372	Transposase
AJS_RS14545	COG0583	DNA-binding transcription factor activity
AJS_RS14580	COG3039	Transposase
AJS_RS14605	COG1192	Involved in chromosome partitioning
AJS_RS14640	COG5489	Protein of unknown function (DUF736)
AJS_RS14670	COG1192	Involved in chromosome partitioning
AJS_RS14695	COG0419	ATPase involved in DNA repair
AJS_RS14705	COG3039	Transposase
AJS_RS14715	COG3657	addiction module killer protein
AJS_RS14725	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AJS_RS14730	COG0724	RNA recognition motif
AJS_RS14745	COG0300	oxidoreductase activity
AJS_RS14765	COG0840	transmembrane signaling receptor activity
AJS_RS14770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AJS_RS14790	COG3040	lipid binding
AJS_RS14805	COG1346	cytolysis
AJS_RS14810	COG0583	DNA-binding transcription factor activity
AJS_RS14815	COG1960	acyl-CoA dehydrogenase activity
AJS_RS14820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS14835	COG0840	transmembrane signaling receptor activity
AJS_RS14875	COG0617	tRNA 3'-terminal CCA addition
AJS_RS14885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AJS_RS14890	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AJS_RS14900	COG0589	response to stress
AJS_RS14915	COG0728	peptidoglycan biosynthetic process
AJS_RS14920	COG0268	Binds directly to 16S ribosomal RNA
AJS_RS14930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AJS_RS14935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AJS_RS14965	COG0489	protein tyrosine kinase activity
AJS_RS14975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AJS_RS15040	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AJS_RS15060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AJS_RS15075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AJS_RS15095	COG1739	Uncharacterized protein family UPF0029
AJS_RS15120	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AJS_RS15125	COG1061	Type III restriction enzyme res subunit
AJS_RS15145	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
AJS_RS15150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AJS_RS15165	COG1132	(ABC) transporter
AJS_RS15220	COG0456	acetyltransferase
AJS_RS15230	COG1213	nucleotidyl transferase
AJS_RS15240	COG2124	cytochrome p450
AJS_RS15250	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS15305	COG4584	PFAM Integrase catalytic
AJS_RS15355	COG3039	Transposase
AJS_RS15375	COG4603	Belongs to the binding-protein-dependent transport system permease family
AJS_RS15380	COG1129	ABC transporter
AJS_RS15390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AJS_RS15395	COG5002	protein histidine kinase activity
AJS_RS15395	COG3447	MASE1 domain protein
AJS_RS15395	COG5001	Diguanylate cyclase
AJS_RS15410	COG5001	Diguanylate cyclase
AJS_RS15410	COG3300	MHYT domain
AJS_RS15415	COG0537	adenosine 5'-monophosphoramidase activity
AJS_RS15420	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AJS_RS15425	COG2814	Major facilitator Superfamily
AJS_RS15430	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AJS_RS15435	COG1136	(ABC) transporter
AJS_RS15440	COG0071	Belongs to the small heat shock protein (HSP20) family
AJS_RS15450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AJS_RS15505	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AJS_RS15515	COG1122	ATPase activity
AJS_RS15540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AJS_RS15550	COG2814	Major facilitator Superfamily
AJS_RS15555	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS15565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AJS_RS15570	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AJS_RS15585	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS15590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AJS_RS15595	COG0583	DNA-binding transcription factor activity
AJS_RS15610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AJS_RS15615	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AJS_RS15625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AJS_RS15635	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS15655	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AJS_RS15660	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AJS_RS15660	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AJS_RS15665	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AJS_RS15675	COG0560	Phosphoserine phosphatase
AJS_RS15690	COG0583	DNA-binding transcription factor activity
AJS_RS15695	COG1959	2 iron, 2 sulfur cluster binding
AJS_RS15715	COG0667	Aldo Keto reductase
AJS_RS15720	COG2900	Belongs to the SlyX family
AJS_RS15725	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AJS_RS15730	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AJS_RS15760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AJS_RS15765	COG0778	Nitroreductase
AJS_RS15770	COG1492	cobalamin metabolic process
AJS_RS15780	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AJS_RS15830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AJS_RS15830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AJS_RS15835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AJS_RS15870	COG0542	response to heat
AJS_RS15875	COG0314	molybdopterin synthase activity
AJS_RS15895	COG0303	'Molybdopterin
AJS_RS15900	COG1763	Mo-molybdopterin cofactor biosynthetic process
AJS_RS15915	COG0436	Aminotransferase
AJS_RS15925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AJS_RS15930	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AJS_RS15945	COG0359	binds to the 23S rRNA
AJS_RS15950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AJS_RS15955	COG2965	DNA replication, synthesis of RNA primer
AJS_RS15960	COG0360	Binds together with S18 to 16S ribosomal RNA
AJS_RS15965	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AJS_RS15970	COG0443	Heat shock 70 kDa protein
AJS_RS15975	COG0484	heat shock protein binding
AJS_RS15980	COG0826	peptidase U32
AJS_RS15985	COG0826	peptidase U32
AJS_RS15990	COG3154	lipid carrier protein
AJS_RS16005	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AJS_RS16015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AJS_RS16025	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AJS_RS16040	COG0066	3-isopropylmalate dehydratase activity
AJS_RS16045	COG0473	3-isopropylmalate dehydrogenase activity
AJS_RS16055	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AJS_RS16065	COG0101	tRNA pseudouridine synthase activity
AJS_RS16070	COG0135	phosphoribosylanthranilate isomerase activity
AJS_RS16075	COG0133	tryptophan synthase activity
AJS_RS16080	COG0159	tryptophan synthase activity
AJS_RS16085	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AJS_RS16090	COG0762	integral membrane protein
AJS_RS16100	COG0438	transferase activity, transferring glycosyl groups
AJS_RS16105	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AJS_RS16130	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AJS_RS16135	COG0745	RESPONSE REGULATOR receiver
AJS_RS16175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AJS_RS16185	COG1472	Belongs to the glycosyl hydrolase 3 family
AJS_RS16190	COG0736	holo-[acyl-carrier-protein] synthase activity
AJS_RS16195	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AJS_RS16200	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AJS_RS16205	COG1381	Involved in DNA repair and RecF pathway recombination
AJS_RS16210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AJS_RS16215	COG0571	ribonuclease III activity
AJS_RS16225	COG0681	Belongs to the peptidase S26 family
AJS_RS16230	COG0481	GTPase activity
AJS_RS16235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AJS_RS16260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AJS_RS16265	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AJS_RS16270	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS16275	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AJS_RS16280	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AJS_RS16285	COG0416	fatty acid biosynthetic process
AJS_RS16290	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AJS_RS16295	COG1399	metal-binding, possibly nucleic acid-binding protein
AJS_RS16300	COG0424	maF-like protein
AJS_RS16310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AJS_RS16310	COG0616	signal peptide processing
AJS_RS16325	COG0564	pseudouridine synthase activity
AJS_RS16330	COG1530	ribonuclease E activity
AJS_RS16335	COG3022	response to hydroperoxide
AJS_RS16350	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AJS_RS16350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AJS_RS16355	COG0840	transmembrane signaling receptor activity
AJS_RS16360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AJS_RS16370	COG1304	FMN binding
AJS_RS16400	COG0395	ABC-type sugar transport system, permease component
AJS_RS16405	COG1175	transmembrane transport
AJS_RS16415	COG3842	ATPase activity
AJS_RS16420	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AJS_RS16430	COG0753	catalase activity
AJS_RS16440	COG0165	Argininosuccinate lyase
AJS_RS16445	COG3275	phosphorelay sensor kinase activity
AJS_RS16460	COG0412	Dienelactone hydrolase
AJS_RS16480	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AJS_RS16500	COG0210	DNA helicase
AJS_RS16510	COG0516	GMP reductase activity
AJS_RS16580	COG0582	viral genome integration into host DNA
AJS_RS16585	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AJS_RS16600	COG2814	Major facilitator Superfamily
AJS_RS16605	COG0513	Belongs to the DEAD box helicase family
AJS_RS16610	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AJS_RS16615	COG0501	Belongs to the peptidase M48B family
AJS_RS16620	COG2154	pterin-4-alpha-carbinolamine dehydratase
AJS_RS16625	COG1162	GTPase activity
AJS_RS16630	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AJS_RS16635	COG0494	nUDIX hydrolase
AJS_RS16640	COG0335	large ribosomal subunit rRNA binding
AJS_RS16645	COG0336	Belongs to the RNA methyltransferase TrmD family
AJS_RS16650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AJS_RS16655	COG0228	four-way junction DNA binding
AJS_RS16670	COG0306	phosphate transporter
AJS_RS16675	COG1392	Phosphate transport regulator
AJS_RS16690	COG0411	ABC transporter
AJS_RS16700	COG0559	Belongs to the binding-protein-dependent transport system permease family
AJS_RS16705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AJS_RS16715	COG3039	Transposase
AJS_RS16730	COG2801	Transposase and inactivated derivatives
AJS_RS16755	COG1573	uracil-dna glycosylase
AJS_RS16760	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AJS_RS16765	COG1674	ftsk spoiiie
AJS_RS16770	COG0492	ferredoxin-NADP+ reductase activity
AJS_RS16775	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AJS_RS16780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AJS_RS16790	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AJS_RS16790	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AJS_RS16810	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AJS_RS16815	COG3132	Protein of unknown function, DUF480
AJS_RS16820	COG1960	acyl-CoA dehydrogenase activity
AJS_RS16825	COG1960	acyl-CoA dehydrogenase activity
AJS_RS16830	COG3039	Transposase
AJS_RS16835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AJS_RS16845	COG0196	riboflavin kinase activity
AJS_RS16855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AJS_RS16860	COG1283	sodium-dependent phosphate transmembrane transporter activity
AJS_RS16885	COG0697	spore germination
AJS_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS16925	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AJS_RS16930	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AJS_RS16940	COG0084	hydrolase, TatD family'
AJS_RS16950	COG0640	Transcriptional regulator
AJS_RS16960	COG1136	(ABC) transporter
AJS_RS16965	COG4591	ABC-type transport system involved in lipoprotein release permease component
AJS_RS16970	COG0584	glycerophosphoryl diester phosphodiesterase
AJS_RS16980	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AJS_RS16990	COG3039	Transposase
AJS_RS17010	COG0840	transmembrane signaling receptor activity
AJS_RS17015	COG0613	PHP domain protein
AJS_RS17020	COG0009	L-threonylcarbamoyladenylate synthase
AJS_RS17030	COG0714	Associated with various cellular activities
AJS_RS17035	COG3256	nitric oxide reductase
AJS_RS17040	COG2010	Cytochrome c
AJS_RS17045	COG1994	Peptidase M50
AJS_RS17050	COG0180	Tryptophanyl-tRNA synthetase
AJS_RS17075	COG3706	GGDEF domain
AJS_RS17080	COG5001	Diguanylate cyclase
AJS_RS17080	COG3300	MHYT domain
AJS_RS17085	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AJS_RS17090	COG0517	IMP dehydrogenase activity
AJS_RS17090	COG0617	tRNA 3'-terminal CCA addition
AJS_RS17090	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AJS_RS17095	COG1253	flavin adenine dinucleotide binding
AJS_RS17100	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AJS_RS17105	COG1047	Peptidyl-prolyl cis-trans
AJS_RS17110	COG2003	Belongs to the UPF0758 family
AJS_RS17120	COG1193	negative regulation of DNA recombination
AJS_RS17150	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AJS_RS17155	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AJS_RS17175	COG0437	4 iron, 4 sulfur cluster binding
AJS_RS17180	COG3383	formate dehydrogenase (NAD+) activity
AJS_RS17180	COG0243	molybdopterin cofactor binding
AJS_RS17210	COG3383	formate dehydrogenase (NAD+) activity
AJS_RS17240	COG0489	protein tyrosine kinase activity
AJS_RS17255	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AJS_RS17270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AJS_RS17270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AJS_RS17295	COG0028	Belongs to the TPP enzyme family
AJS_RS17320	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AJS_RS17325	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AJS_RS17340	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AJS_RS17350	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AJS_RS17355	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AJS_RS17360	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AJS_RS17365	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AJS_RS17375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AJS_RS17380	COG0588	phosphoglycerate mutase activity
AJS_RS17385	COG0793	Belongs to the peptidase S41A family
AJS_RS17390	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AJS_RS17400	COG2197	response regulator
AJS_RS17410	COG5487	UPF0391 membrane protein
AJS_RS17435	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AJS_RS17440	COG0742	ribosomal rna small subunit methyltransferase
AJS_RS17445	COG0612	Peptidase, M16
AJS_RS17450	COG0612	Peptidase, M16
AJS_RS17465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AJS_RS17470	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS17485	COG1999	signal sequence binding
AJS_RS17490	COG0109	protoheme IX farnesyltransferase activity
AJS_RS17525	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
AJS_RS17530	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AJS_RS17540	COG2226	methyltransferase
AJS_RS17545	COG1040	competence protein
AJS_RS17550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AJS_RS17560	COG1192	Involved in chromosome partitioning
AJS_RS17565	COG1280	lysine exporter protein (LysE YggA)
AJS_RS17570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AJS_RS17570	COG0475	glutathione-regulated potassium exporter activity
AJS_RS17580	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AJS_RS17585	COG0183	Belongs to the thiolase family
AJS_RS17590	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AJS_RS17600	COG1414	Transcriptional regulator
AJS_RS17625	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AJS_RS17675	COG1178	ABC-type Fe3 transport system permease component
AJS_RS17680	COG3842	ATPase activity
AJS_RS17700	COG0540	Belongs to the ATCase OTCase family
AJS_RS17705	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AJS_RS17710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AJS_RS17715	COG1678	Uncharacterized ACR, COG1678
AJS_RS17720	COG0643	Histidine kinase
AJS_RS17720	COG0784	Response regulator, receiver
AJS_RS17720	COG2198	Histidine kinase
AJS_RS17725	COG0840	transmembrane signaling receptor activity
AJS_RS17750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AJS_RS17765	COG0138	bifunctional purine biosynthesis protein purh
AJS_RS17770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AJS_RS17775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AJS_RS17780	COG1238	metal cluster binding
AJS_RS17810	COG1484	DNA-dependent DNA replication
AJS_RS17815	COG4584	PFAM Integrase catalytic
AJS_RS17835	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AJS_RS17875	COG1196	nuclear chromosome segregation
AJS_RS17880	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AJS_RS17900	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AJS_RS17930	COG0582	viral genome integration into host DNA
AJS_RS17935	COG0012	GTP binding
AJS_RS17940	COG0633	Ferredoxin
AJS_RS17940	COG3217	Mosc domain protein beta barrel domain protein
AJS_RS17945	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AJS_RS17960	COG1024	Enoyl-CoA hydratase
AJS_RS17975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AJS_RS17980	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AJS_RS17985	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AJS_RS18010	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AJS_RS18010	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AJS_RS18015	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AJS_RS18025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AJS_RS18035	COG2264	protein methyltransferase activity
AJS_RS18040	COG0439	Biotin carboxylase
AJS_RS18045	COG0511	ligase activity, forming carbon-carbon bonds
AJS_RS18050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AJS_RS18060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AJS_RS18070	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AJS_RS18080	COG0312	modulator of DNA gyrase
AJS_RS18085	COG0772	Belongs to the SEDS family
AJS_RS18095	COG3150	esterase
AJS_RS18105	COG3474	cytochrome
AJS_RS18120	COG0557	exoribonuclease II activity
AJS_RS18130	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AJS_RS18135	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AJS_RS18140	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AJS_RS18145	COG0840	transmembrane signaling receptor activity
AJS_RS18150	COG0840	transmembrane signaling receptor activity
AJS_RS18155	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AJS_RS18160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AJS_RS18165	COG0840	transmembrane signaling receptor activity
AJS_RS18180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AJS_RS18185	COG1181	Belongs to the D-alanine--D-alanine ligase family
AJS_RS18190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AJS_RS18195	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AJS_RS18200	COG0772	Belongs to the SEDS family
AJS_RS18205	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AJS_RS18210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AJS_RS18215	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AJS_RS18220	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AJS_RS18230	COG3116	cell division
AJS_RS18235	COG0275	rRNA processing
AJS_RS18240	COG2001	Belongs to the MraZ family
AJS_RS18245	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AJS_RS18250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AJS_RS18265	COG0523	cobalamin synthesis protein
AJS_RS18275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AJS_RS18285	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AJS_RS18300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AJS_RS18315	COG2255	four-way junction helicase activity
AJS_RS18325	COG0443	Heat shock 70 kDa protein
AJS_RS18330	COG2249	NAD(P)H dehydrogenase (quinone) activity
AJS_RS18335	COG0443	Heat shock 70 kDa protein
AJS_RS18345	COG0632	four-way junction helicase activity
AJS_RS18350	COG1702	phosphate starvation-inducible protein PhoH
AJS_RS18355	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AJS_RS18365	COG0730	response to heat
AJS_RS18370	COG0513	Belongs to the DEAD box helicase family
AJS_RS18375	COG1490	D-aminoacyl-tRNA deacylase activity
AJS_RS18380	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AJS_RS18390	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AJS_RS18400	COG1131	(ABC) transporter
AJS_RS18405	COG0842	Transport permease protein
AJS_RS18435	COG1250	3-hydroxyacyl-CoA dehydrogenase
AJS_RS18460	COG3568	Endonuclease Exonuclease Phosphatase
AJS_RS18465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AJS_RS18475	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AJS_RS18480	COG2860	membrane
AJS_RS18485	COG1473	amidohydrolase
AJS_RS18510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS18515	COG1024	Enoyl-CoA hydratase
AJS_RS18520	COG1960	acyl-CoA dehydrogenase activity
AJS_RS18525	COG1960	acyl-CoA dehydrogenase activity
AJS_RS18530	COG0183	Belongs to the thiolase family
AJS_RS18535	COG1250	3-hydroxyacyl-CoA dehydrogenase
AJS_RS18535	COG1024	Enoyl-CoA hydratase
AJS_RS18540	COG0583	DNA-binding transcription factor activity
AJS_RS18550	COG0501	Belongs to the peptidase M48B family
AJS_RS18565	COG0418	dihydroorotase activity
AJS_RS18575	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AJS_RS18580	COG0683	leucine binding
AJS_RS18585	COG0683	leucine binding
AJS_RS18600	COG0477	Major facilitator Superfamily
AJS_RS18630	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AJS_RS18635	COG4770	biotin carboxylase activity
AJS_RS18645	COG1024	Enoyl-CoA hydratase
AJS_RS18650	COG2318	DinB family
AJS_RS18655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AJS_RS18660	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS18670	COG3039	Transposase
AJS_RS18690	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS18700	COG3012	SEC-C Motif Domain Protein
AJS_RS18705	COG0840	transmembrane signaling receptor activity
AJS_RS18710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AJS_RS18715	COG1960	acyl-CoA dehydrogenase activity
AJS_RS18720	COG0300	oxidoreductase activity
AJS_RS18725	COG0183	Belongs to the thiolase family
AJS_RS18730	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AJS_RS18735	COG0288	reversible hydration of carbon dioxide
AJS_RS18740	COG1960	acyl-CoA dehydrogenase activity
AJS_RS18745	COG0789	Transcriptional regulator
AJS_RS18755	COG3328	transposase activity
AJS_RS18795	COG0488	(ABC) transporter
AJS_RS18800	COG2201	protein-glutamate methylesterase activity
AJS_RS18805	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AJS_RS18815	COG0835	chemotaxis
AJS_RS18820	COG0643	Histidine kinase
AJS_RS18820	COG2198	Histidine kinase
AJS_RS18825	COG2201	protein-glutamate methylesterase activity
AJS_RS18840	COG2197	response regulator
AJS_RS18850	COG1987	bacterial-type flagellum assembly
AJS_RS18855	COG1338	Plays a role in the flagellum-specific transport system
AJS_RS18865	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AJS_RS18905	COG1766	The M ring may be actively involved in energy transduction
AJS_RS18910	COG1677	Flagellar hook-basal body complex protein FliE
AJS_RS18930	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AJS_RS18935	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AJS_RS18940	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AJS_RS18955	COG0745	RESPONSE REGULATOR receiver
AJS_RS18960	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AJS_RS18970	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AJS_RS18985	COG1191	sigma factor activity
AJS_RS19005	COG1815	bacterial-type flagellum-dependent cell motility
AJS_RS19010	COG1558	bacterial-type flagellum-dependent cell motility
AJS_RS19015	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AJS_RS19035	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AJS_RS19045	COG1706	bacterial-type flagellum-dependent cell motility
AJS_RS19050	COG3951	Flagellar rod assembly protein muramidase FlgJ
AJS_RS19050	COG1705	Flagellar rod assembly protein muramidase FlgJ
AJS_RS19060	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AJS_RS19070	COG0733	neurotransmitter:sodium symporter activity
AJS_RS19075	COG2070	2-Nitropropane dioxygenase
AJS_RS19080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AJS_RS19090	COG0697	spore germination
AJS_RS19095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AJS_RS19100	COG0384	phenazine biosynthesis protein PhzF
AJS_RS19105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AJS_RS19135	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AJS_RS19140	COG4232	protein-disulfide reductase activity
AJS_RS19150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AJS_RS19155	COG1832	CoA-binding protein
AJS_RS19165	COG0861	Integral membrane protein TerC family
AJS_RS19170	COG0583	DNA-binding transcription factor activity
AJS_RS19175	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AJS_RS19180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AJS_RS19190	COG0679	Auxin Efflux Carrier
AJS_RS19195	COG0210	DNA helicase
AJS_RS19215	COG0589	response to stress
AJS_RS19220	COG0343	queuine tRNA-ribosyltransferase activity
AJS_RS19250	COG1522	sequence-specific DNA binding
AJS_RS19255	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AJS_RS19260	COG0204	Acyl-transferase
AJS_RS19260	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS19285	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS19290	COG2072	flavoprotein involved in K transport
AJS_RS19300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AJS_RS19320	COG2365	Tyrosine phosphatase family
AJS_RS19330	COG2204	response regulator
AJS_RS19335	COG5000	phosphorelay sensor kinase activity
AJS_RS19345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AJS_RS19345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AJS_RS19355	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AJS_RS19360	COG0085	RNA polymerase activity
AJS_RS19365	COG0222	ribosome binding
AJS_RS19370	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AJS_RS19375	COG0081	regulation of translation
AJS_RS19380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AJS_RS19390	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AJS_RS19400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AJS_RS19455	COG0189	ligase activity
AJS_RS19460	COG3135	benzoate transporter
AJS_RS19465	COG3158	transport of potassium into the cell
AJS_RS19475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AJS_RS19480	COG0569	domain protein
AJS_RS19485	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AJS_RS19505	COG0495	leucyl-tRNA aminoacylation
AJS_RS19515	COG0668	transmembrane transport
AJS_RS19530	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AJS_RS19535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AJS_RS19540	COG0735	belongs to the Fur family
AJS_RS19545	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AJS_RS19555	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AJS_RS19560	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AJS_RS19575	COG3118	belongs to the thioredoxin family
AJS_RS19580	COG0693	protein deglycase activity
AJS_RS19595	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AJS_RS19600	COG0009	L-threonylcarbamoyladenylate synthase
AJS_RS19615	COG2027	D-alanyl-D-alanine carboxypeptidase
AJS_RS19635	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AJS_RS19640	COG2414	aldehyde ferredoxin oxidoreductase
AJS_RS19665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AJS_RS19670	COG0318	PFAM AMP-dependent synthetase and ligase
AJS_RS19700	COG0469	pyruvate kinase activity
AJS_RS19705	COG0006	proline dipeptidase activity
AJS_RS19720	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AJS_RS19725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AJS_RS19740	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AJS_RS19745	COG1047	Peptidyl-prolyl cis-trans
AJS_RS19765	COG1028	Short-chain dehydrogenase reductase Sdr
AJS_RS19775	COG3148	PFAM DTW domain containing protein
AJS_RS19805	COG0625	glutathione transferase activity
AJS_RS19870	COG3181	Tripartite tricarboxylate transporter family receptor
AJS_RS19875	COG0583	DNA-binding transcription factor activity
AJS_RS19880	COG0642	Histidine kinase
AJS_RS19895	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AJS_RS19900	COG2137	regulation of response to DNA damage stimulus
AJS_RS19910	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AJS_RS19915	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AJS_RS19920	COG1862	Preprotein translocase
AJS_RS19925	COG0668	transmembrane transport
AJS_RS19935	COG1522	sequence-specific DNA binding
AJS_RS19950	COG2814	Major facilitator Superfamily
AJS_RS19955	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
AJS_RS19965	COG4566	intracellular signal transduction
AJS_RS19985	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AJS_RS20000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AJS_RS20015	COG0625	glutathione transferase activity
AJS_RS20040	COG0861	Integral membrane protein TerC family
AJS_RS20050	COG1950	PFAM Membrane protein of
AJS_RS20055	COG4783	chaperone-mediated protein folding
AJS_RS20060	COG0315	cyclic pyranopterin monophosphate synthase activity
AJS_RS20070	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
AJS_RS20085	COG0315	cyclic pyranopterin monophosphate synthase activity
AJS_RS20095	COG4969	Belongs to the N-Me-Phe pilin family
AJS_RS20110	COG1716	ATPase activity
AJS_RS20120	COG0861	Integral membrane protein TerC family
AJS_RS20125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AJS_RS20130	COG0045	succinate-CoA ligase (ADP-forming) activity
AJS_RS20135	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AJS_RS20140	COG0758	DNA mediated transformation
AJS_RS20150	COG0242	peptide deformylase activity
AJS_RS20160	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AJS_RS20175	COG0126	phosphoglycerate kinase activity
AJS_RS20185	COG0284	orotidine-5'-phosphate decarboxylase activity
AJS_RS20205	COG0840	transmembrane signaling receptor activity
AJS_RS20210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AJS_RS20220	COG2814	Major facilitator Superfamily
AJS_RS20225	COG0629	single-stranded DNA binding
AJS_RS20230	COG1620	l-lactate permease
AJS_RS20235	COG0482	sulfurtransferase activity
AJS_RS20245	COG1053	succinate dehydrogenase
AJS_RS20300	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AJS_RS20305	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AJS_RS20345	COG1477	protein flavinylation
AJS_RS20360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AJS_RS20370	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AJS_RS20380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AJS_RS20445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AJS_RS20450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AJS_RS20455	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AJS_RS20465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AJS_RS20480	COG1196	nuclear chromosome segregation
AJS_RS20495	COG2267	carboxylic ester hydrolase activity
AJS_RS20510	COG0840	transmembrane signaling receptor activity
AJS_RS20515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AJS_RS20520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AJS_RS20525	COG2119	membrane
AJS_RS20530	COG0724	RNA recognition motif
AJS_RS20535	COG0724	RNA recognition motif
AJS_RS20540	COG0300	oxidoreductase activity
AJS_RS20550	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AJS_RS20565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AJS_RS20585	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AJS_RS20590	COG0747	negative chemotaxis
AJS_RS20595	COG0706	membrane insertase activity
AJS_RS20600	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AJS_RS20605	COG0594	ribonuclease P activity
AJS_RS20610	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AJS_RS20615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AJS_RS20635	COG0456	acetyltransferase
AJS_RS20645	COG1764	response to oxidative stress
AJS_RS20655	COG1254	Belongs to the acylphosphatase family
AJS_RS20685	COG1199	ATP-dependent helicase activity
AJS_RS20795	COG0183	Belongs to the thiolase family
AJS_RS21190	COG1301	dicarboxylic acid transport
AJS_RS21470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AJS_RS21570	COG2963	transposase activity