locus-tag	class	description
BSY15_RS00015	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BSY15_RS00025	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS00030	COG1492	cobalamin metabolic process
BSY15_RS00050	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY15_RS00060	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BSY15_RS00065	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BSY15_RS00070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BSY15_RS00075	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
BSY15_RS00090	COG4206	TonB-dependent receptor
BSY15_RS00105	COG0730	response to heat
BSY15_RS00115	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BSY15_RS00115	COG2199	diguanylate cyclase activity
BSY15_RS00130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY15_RS00165	COG3278	Belongs to the heme-copper respiratory oxidase family
BSY15_RS00185	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS00205	COG1802	Transcriptional regulator
BSY15_RS00210	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BSY15_RS00215	COG0583	DNA-binding transcription factor activity
BSY15_RS00220	COG0129	dihydroxy-acid dehydratase activity
BSY15_RS00230	COG4654	Cytochrome c, class I
BSY15_RS00240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY15_RS00250	COG0114	fumarate hydratase activity
BSY15_RS00260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BSY15_RS00265	COG1451	nucleotide metabolic process
BSY15_RS00295	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSY15_RS00300	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSY15_RS00305	COG0740	serine-type endopeptidase activity
BSY15_RS00310	COG0544	peptidyl-prolyl cis-trans isomerase activity
BSY15_RS00320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY15_RS00330	COG1562	ergosterol biosynthetic process
BSY15_RS00335	COG1760	l-serine dehydratase
BSY15_RS00340	COG1562	ergosterol biosynthetic process
BSY15_RS00345	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BSY15_RS00380	COG1011	Hydrolase
BSY15_RS00385	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BSY15_RS00390	COG1067	ATP-dependent peptidase activity
BSY15_RS00400	COG3328	transposase activity
BSY15_RS00410	COG0596	Alpha beta hydrolase
BSY15_RS00415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY15_RS00465	COG1677	Flagellar hook-basal body complex protein FliE
BSY15_RS00515	COG0431	NADPH-dependent FMN reductase
BSY15_RS00520	COG0798	PFAM Bile acid sodium symporter
BSY15_RS00530	COG0640	Transcriptional regulator
BSY15_RS00650	COG2721	sulfolactate sulfo-lyase activity
BSY15_RS00660	COG4948	Mandelate Racemase Muconate Lactonizing
BSY15_RS00675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY15_RS00680	COG1802	Transcriptional regulator
BSY15_RS00725	COG0411	ABC transporter
BSY15_RS00730	COG4733	cellulase activity
BSY15_RS00730	COG5297	Belongs to the glycosyl hydrolase family 6
BSY15_RS00740	COG2204	response regulator
BSY15_RS00775	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BSY15_RS00780	COG0582	viral genome integration into host DNA
BSY15_RS00795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BSY15_RS00805	COG4983	Phage plasmid primase, P4 family domain protein
BSY15_RS00830	COG0037	tRNA processing
BSY15_RS00835	COG0825	malonyl-CoA metabolic process
BSY15_RS00845	COG0215	cysteine-tRNA ligase activity
BSY15_RS00870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY15_RS00875	COG3228	Belongs to the MtfA family
BSY15_RS00890	COG1522	sequence-specific DNA binding
BSY15_RS00900	COG3384	dioxygenase
BSY15_RS00910	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BSY15_RS00920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY15_RS00980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY15_RS01005	COG1525	nuclease
BSY15_RS01025	COG0564	pseudouridine synthase activity
BSY15_RS01035	COG1285	pathogenesis
BSY15_RS01080	COG2072	flavoprotein involved in K transport
BSY15_RS01095	COG2267	carboxylic ester hydrolase activity
BSY15_RS01105	COG2918	glutathione biosynthetic process
BSY15_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS01125	COG0633	Ferredoxin
BSY15_RS01135	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BSY15_RS01140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY15_RS01145	COG0436	Aminotransferase
BSY15_RS01150	COG0824	Thioesterase
BSY15_RS01175	COG0477	Major facilitator Superfamily
BSY15_RS01180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BSY15_RS01185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY15_RS01190	COG1845	cytochrome c oxidase, subunit III
BSY15_RS01195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BSY15_RS01200	COG3346	SURF1 family
BSY15_RS01205	COG2205	protein histidine kinase activity
BSY15_RS01210	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BSY15_RS01235	COG0039	L-malate dehydrogenase activity
BSY15_RS01240	COG2188	Transcriptional regulator
BSY15_RS01250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BSY15_RS01255	COG1053	succinate dehydrogenase
BSY15_RS01260	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BSY15_RS01265	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BSY15_RS01270	COG0372	Belongs to the citrate synthase family
BSY15_RS01280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BSY15_RS01285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BSY15_RS01305	COG4191	Histidine kinase
BSY15_RS01310	COG3437	response regulator, receiver
BSY15_RS01315	COG2194	sulfuric ester hydrolase activity
BSY15_RS01330	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY15_RS01350	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS01365	COG1196	nuclear chromosome segregation
BSY15_RS01365	COG3264	Mechanosensitive ion channel
BSY15_RS01370	COG1024	Enoyl-CoA hydratase
BSY15_RS01375	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSY15_RS01380	COG0714	Associated with various cellular activities
BSY15_RS01395	COG2951	lytic endotransglycosylase activity
BSY15_RS01400	COG0683	leucine binding
BSY15_RS01410	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BSY15_RS01415	COG0683	leucine binding
BSY15_RS01425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY15_RS01430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS01435	COG1116	anion transmembrane transporter activity
BSY15_RS01440	COG0517	IMP dehydrogenase activity
BSY15_RS01455	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS01460	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY15_RS01465	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY15_RS01470	COG3265	gluconokinase activity
BSY15_RS01475	COG1609	Transcriptional regulator
BSY15_RS01480	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS01485	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BSY15_RS01495	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS01510	COG1846	Transcriptional regulator
BSY15_RS01515	COG0840	transmembrane signaling receptor activity
BSY15_RS01520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BSY15_RS01535	COG0243	molybdopterin cofactor binding
BSY15_RS01540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSY15_RS01555	COG1607	acyl-coa hydrolase
BSY15_RS01575	COG2081	HI0933 family
BSY15_RS01585	COG3300	MHYT domain
BSY15_RS01585	COG5001	Diguanylate cyclase
BSY15_RS01590	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BSY15_RS01600	COG0583	DNA-binding transcription factor activity
BSY15_RS01605	COG0473	3-isopropylmalate dehydrogenase activity
BSY15_RS01615	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BSY15_RS01620	COG0415	Belongs to the DNA photolyase family
BSY15_RS01625	COG3046	protein related to deoxyribodipyrimidine photolyase
BSY15_RS01630	COG0312	modulator of DNA gyrase
BSY15_RS01635	COG3028	Belongs to the UPF0307 family
BSY15_RS01640	COG0521	Mo-molybdopterin cofactor biosynthetic process
BSY15_RS01650	COG1045	serine acetyltransferase
BSY15_RS01660	COG0483	inositol monophosphate 1-phosphatase activity
BSY15_RS01670	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BSY15_RS01710	COG1968	undecaprenyl-diphosphatase activity
BSY15_RS01730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY15_RS01755	COG3275	phosphorelay sensor kinase activity
BSY15_RS01760	COG3279	Response regulator of the LytR AlgR family
BSY15_RS01765	COG4133	protoheme IX ABC transporter activity
BSY15_RS01775	COG1234	tRNA 3'-trailer cleavage
BSY15_RS01805	COG0745	RESPONSE REGULATOR receiver
BSY15_RS01825	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BSY15_RS01830	COG3608	succinylglutamate desuccinylase aspartoacylase
BSY15_RS01830	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BSY15_RS01885	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BSY15_RS01930	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY15_RS01935	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY15_RS01940	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BSY15_RS01945	COG0142	geranyltranstransferase activity
BSY15_RS01950	COG1722	exodeoxyribonuclease VII activity
BSY15_RS01995	COG0628	permease
BSY15_RS02000	COG5001	Diguanylate cyclase
BSY15_RS02005	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BSY15_RS02010	COG0181	hydroxymethylbilane synthase activity
BSY15_RS02040	COG2353	YceI-like domain
BSY15_RS02050	COG0525	valine-tRNA ligase activity
BSY15_RS02055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BSY15_RS02060	COG0425	Belongs to the sulfur carrier protein TusA family
BSY15_RS02125	COG0582	viral genome integration into host DNA
BSY15_RS02140	COG0583	DNA-binding transcription factor activity
BSY15_RS02145	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS02165	COG0835	chemotaxis
BSY15_RS02165	COG0784	Response regulator, receiver
BSY15_RS02195	COG4566	intracellular signal transduction
BSY15_RS02210	COG0617	tRNA 3'-terminal CCA addition
BSY15_RS02220	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY15_RS02230	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BSY15_RS02255	COG1917	Cupin 2, conserved barrel domain protein
BSY15_RS02255	COG4977	sequence-specific DNA binding
BSY15_RS02260	COG0840	transmembrane signaling receptor activity
BSY15_RS02285	COG0728	peptidoglycan biosynthetic process
BSY15_RS02290	COG0268	Binds directly to 16S ribosomal RNA
BSY15_RS02300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BSY15_RS02305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BSY15_RS02330	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BSY15_RS02340	COG3483	tryptophan 2,3-dioxygenase activity
BSY15_RS02355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY15_RS02370	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BSY15_RS02390	COG2916	Histone family protein nucleoid-structuring protein H-NS
BSY15_RS02395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BSY15_RS02400	COG1477	protein flavinylation
BSY15_RS02410	COG4263	nitrous-oxide reductase activity
BSY15_RS02415	COG3901	Regulator of nitric oxide reductase transcription
BSY15_RS02415	COG0348	domain, Protein
BSY15_RS02430	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
BSY15_RS02445	COG0513	Belongs to the DEAD box helicase family
BSY15_RS02450	COG2321	neutral zinc metallopeptidase
BSY15_RS02455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BSY15_RS02460	COG2423	ornithine cyclodeaminase activity
BSY15_RS02465	COG0717	Belongs to the dCTP deaminase family
BSY15_RS02470	COG0402	S-adenosylhomocysteine deaminase activity
BSY15_RS02480	COG0537	adenosine 5'-monophosphoramidase activity
BSY15_RS02485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BSY15_RS02500	COG3845	ABC transporter
BSY15_RS02515	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY15_RS02525	COG1136	(ABC) transporter
BSY15_RS02530	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSY15_RS02540	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BSY15_RS02550	COG0613	PHP domain protein
BSY15_RS02555	COG0009	L-threonylcarbamoyladenylate synthase
BSY15_RS02570	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BSY15_RS02575	COG3132	Protein of unknown function, DUF480
BSY15_RS02580	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS02585	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS02600	COG0196	riboflavin kinase activity
BSY15_RS02605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BSY15_RS02610	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSY15_RS02615	COG1283	sodium-dependent phosphate transmembrane transporter activity
BSY15_RS02635	COG0697	spore germination
BSY15_RS02650	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS02675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSY15_RS02690	COG0084	hydrolase, TatD family'
BSY15_RS02695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY15_RS02700	COG0714	Associated with various cellular activities
BSY15_RS02715	COG5002	protein histidine kinase activity
BSY15_RS02715	COG5001	Diguanylate cyclase
BSY15_RS02715	COG3447	MASE1 domain protein
BSY15_RS02765	COG2186	Transcriptional regulator
BSY15_RS02785	COG2233	PERMEase
BSY15_RS02790	COG0280	phosphate acetyltransferase
BSY15_RS02790	COG0281	malic enzyme
BSY15_RS02795	COG1639	'signal transduction protein
BSY15_RS02810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS02815	COG4585	Histidine kinase
BSY15_RS02820	COG2197	response regulator
BSY15_RS02835	COG1752	Esterase of the alpha-beta hydrolase superfamily
BSY15_RS02840	COG0829	nickel cation binding
BSY15_RS02850	COG0436	Aminotransferase
BSY15_RS02865	COG1597	lipid kinase activity
BSY15_RS02920	COG0831	urea catabolic process
BSY15_RS02930	COG0832	Belongs to the urease beta subunit family
BSY15_RS02935	COG0804	urea catabolic process
BSY15_RS02945	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BSY15_RS02950	COG0830	nickel cation binding
BSY15_RS02955	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BSY15_RS02970	COG3300	MHYT domain
BSY15_RS02970	COG5001	Diguanylate cyclase
BSY15_RS02980	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BSY15_RS02985	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BSY15_RS03005	COG1561	YicC-like family, N-terminal region
BSY15_RS03010	COG0194	GDP metabolic process
BSY15_RS03015	COG1758	RNA polymerase activity
BSY15_RS03020	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSY15_RS03040	COG1420	regulation of RNA biosynthetic process
BSY15_RS03045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BSY15_RS03050	COG0497	DNA recombination
BSY15_RS03055	COG1660	Displays ATPase and GTPase activities
BSY15_RS03060	COG1194	a g-specific adenine glycosylase
BSY15_RS03070	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BSY15_RS03085	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BSY15_RS03095	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BSY15_RS03100	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BSY15_RS03105	COG0193	aminoacyl-tRNA hydrolase activity
BSY15_RS03110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BSY15_RS03120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY15_RS03125	COG0444	Belongs to the ABC transporter superfamily
BSY15_RS03130	COG4608	Belongs to the ABC transporter superfamily
BSY15_RS03135	COG0747	negative chemotaxis
BSY15_RS03140	COG0154	amidase activity
BSY15_RS03185	COG0302	gtp cyclohydrolase
BSY15_RS03190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY15_RS03200	COG0745	RESPONSE REGULATOR receiver
BSY15_RS03215	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BSY15_RS03230	COG3344	reverse transcriptase
BSY15_RS03235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSY15_RS03240	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY15_RS03255	COG2226	methyltransferase
BSY15_RS03275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSY15_RS03285	COG1175	transmembrane transport
BSY15_RS03290	COG0395	ABC-type sugar transport system, permease component
BSY15_RS03295	COG3842	ATPase activity
BSY15_RS03300	COG0584	glycerophosphoryl diester phosphodiesterase
BSY15_RS03305	COG1511	domain protein
BSY15_RS03305	COG3264	Mechanosensitive ion channel
BSY15_RS03320	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BSY15_RS03325	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BSY15_RS03330	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY15_RS03335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BSY15_RS03340	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BSY15_RS03345	COG1253	flavin adenine dinucleotide binding
BSY15_RS03350	COG0741	lytic transglycosylase activity
BSY15_RS03355	COG0442	prolyl-tRNA aminoacylation
BSY15_RS03360	COG0494	nUDIX hydrolase
BSY15_RS03365	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BSY15_RS03370	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BSY15_RS03375	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BSY15_RS03380	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BSY15_RS03385	COG0142	geranyltranstransferase activity
BSY15_RS03410	COG0237	dephospho-CoA kinase activity
BSY15_RS03415	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BSY15_RS03420	COG0494	nUDIX hydrolase
BSY15_RS03430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BSY15_RS03435	COG0653	protein targeting
BSY15_RS03440	COG0739	heme binding
BSY15_RS03450	COG2969	positive regulation of protein catabolic process
BSY15_RS03455	COG0625	glutathione transferase activity
BSY15_RS03460	COG2857	Cytochrome c1
BSY15_RS03465	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BSY15_RS03475	COG1970	mechanosensitive ion channel activity
BSY15_RS03480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BSY15_RS03485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BSY15_RS03500	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BSY15_RS03505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY15_RS03510	COG0805	protein transport
BSY15_RS03515	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY15_RS03520	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BSY15_RS03540	COG0140	phosphoribosyl-ATP diphosphatase activity
BSY15_RS03545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BSY15_RS03550	COG0107	imidazoleglycerol-phosphate synthase activity
BSY15_RS03555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BSY15_RS03600	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BSY15_RS03610	COG0131	Imidazoleglycerol-phosphate dehydratase
BSY15_RS03615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BSY15_RS03630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY15_RS03645	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BSY15_RS03650	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BSY15_RS03655	COG5007	Belongs to the BolA IbaG family
BSY15_RS03660	COG0842	Transport permease protein
BSY15_RS03665	COG1131	(ABC) transporter
BSY15_RS03680	COG2853	Lipoprotein
BSY15_RS03685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BSY15_RS03690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSY15_RS03695	COG1127	ABC transporter
BSY15_RS03705	COG0067	glutamate synthase
BSY15_RS03705	COG0069	glutamate synthase activity
BSY15_RS03705	COG0070	glutamate synthase
BSY15_RS03725	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BSY15_RS03730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BSY15_RS03765	COG1965	Belongs to the frataxin family
BSY15_RS03775	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BSY15_RS03780	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY15_RS03785	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY15_RS03790	COG1333	cytochrome c biogenesis protein
BSY15_RS03800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BSY15_RS03810	COG1560	Kdo2-lipid A biosynthetic process
BSY15_RS03820	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BSY15_RS03845	COG1056	cytidyltransferase-related domain
BSY15_RS03845	COG1051	belongs to the nudix hydrolase family
BSY15_RS03850	COG3706	GGDEF domain
BSY15_RS03855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BSY15_RS03860	COG0459	protein refolding
BSY15_RS03865	COG0800	Aldolase
BSY15_RS03890	COG0166	Belongs to the GPI family
BSY15_RS03895	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BSY15_RS03910	COG0346	lactoylglutathione lyase activity
BSY15_RS03915	COG0837	glucose binding
BSY15_RS03920	COG3842	ATPase activity
BSY15_RS03925	COG0395	ABC-type sugar transport system, permease component
BSY15_RS03930	COG1175	transmembrane transport
BSY15_RS03965	COG0587	DNA-directed DNA polymerase activity
BSY15_RS04000	COG2801	Transposase and inactivated derivatives
BSY15_RS04025	COG2963	transposase activity
BSY15_RS04045	COG3706	GGDEF domain
BSY15_RS04050	COG2205	protein histidine kinase activity
BSY15_RS04055	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY15_RS04075	COG0583	DNA-binding transcription factor activity
BSY15_RS04080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BSY15_RS04085	COG0739	heme binding
BSY15_RS04090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BSY15_RS04095	COG0316	Belongs to the HesB IscA family
BSY15_RS04110	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BSY15_RS04115	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BSY15_RS04125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BSY15_RS04130	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BSY15_RS04145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BSY15_RS04155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BSY15_RS04185	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BSY15_RS04190	COG0683	leucine binding
BSY15_RS04195	COG0683	leucine binding
BSY15_RS04205	COG0477	Major facilitator Superfamily
BSY15_RS04230	COG0583	DNA-binding transcription factor activity
BSY15_RS04235	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS04240	COG3246	L-lysine catabolic process to acetate
BSY15_RS04245	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS04255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BSY15_RS04270	COG1024	Enoyl-CoA hydratase
BSY15_RS04275	COG2318	DinB family
BSY15_RS04285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY15_RS04290	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS04305	COG2963	transposase activity
BSY15_RS04310	COG2801	Transposase and inactivated derivatives
BSY15_RS04325	COG0625	glutathione transferase activity
BSY15_RS04335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY15_RS04340	COG3012	SEC-C Motif Domain Protein
BSY15_RS04370	COG1063	alcohol dehydrogenase
BSY15_RS04390	COG2205	protein histidine kinase activity
BSY15_RS04395	COG5002	protein histidine kinase activity
BSY15_RS04400	COG0840	transmembrane signaling receptor activity
BSY15_RS04410	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS04430	COG0183	Belongs to the thiolase family
BSY15_RS04435	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BSY15_RS04440	COG0288	reversible hydration of carbon dioxide
BSY15_RS04445	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS04455	COG0789	Transcriptional regulator
BSY15_RS04475	COG2801	Transposase and inactivated derivatives
BSY15_RS04485	COG2963	transposase activity
BSY15_RS04520	COG1706	bacterial-type flagellum-dependent cell motility
BSY15_RS04545	COG0583	DNA-binding transcription factor activity
BSY15_RS04550	COG2910	NAD(P)H-binding
BSY15_RS04555	COG0436	Aminotransferase
BSY15_RS04580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY15_RS04585	COG0625	glutathione transferase activity
BSY15_RS04595	COG0384	phenazine biosynthesis protein PhzF
BSY15_RS04630	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS04640	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS04665	COG0724	RNA recognition motif
BSY15_RS04690	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY15_RS04705	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY15_RS04710	COG1832	CoA-binding protein
BSY15_RS04725	COG0861	Integral membrane protein TerC family
BSY15_RS04730	COG0583	DNA-binding transcription factor activity
BSY15_RS04755	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BSY15_RS04765	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BSY15_RS04780	COG1473	amidohydrolase
BSY15_RS04800	COG0679	Auxin Efflux Carrier
BSY15_RS04810	COG0210	DNA helicase
BSY15_RS04855	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS04865	COG0343	queuine tRNA-ribosyltransferase activity
BSY15_RS04910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BSY15_RS04915	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS04915	COG0204	Acyl-transferase
BSY15_RS04940	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY15_RS04955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY15_RS04960	COG1253	flavin adenine dinucleotide binding
BSY15_RS04975	COG2847	Copper chaperone PCu(A)C
BSY15_RS04995	COG0625	glutathione transferase activity
BSY15_RS05025	COG0583	DNA-binding transcription factor activity
BSY15_RS05035	COG0203	ribosomal protein L17
BSY15_RS05040	COG0202	RNA polymerase activity
BSY15_RS05045	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BSY15_RS05050	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BSY15_RS05055	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BSY15_RS05060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BSY15_RS05065	COG0201	protein transport
BSY15_RS05070	COG0200	Binds to the 23S rRNA
BSY15_RS05075	COG1841	ribosomal large subunit assembly
BSY15_RS05080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BSY15_RS05085	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BSY15_RS05090	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BSY15_RS05095	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BSY15_RS05100	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BSY15_RS05105	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BSY15_RS05110	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BSY15_RS05115	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BSY15_RS05120	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BSY15_RS05135	COG0395	ABC-type sugar transport system, permease component
BSY15_RS05145	COG3842	ATPase activity
BSY15_RS05150	COG3842	ATPase activity
BSY15_RS05160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BSY15_RS05170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BSY15_RS05175	COG2205	protein histidine kinase activity
BSY15_RS05175	COG3437	response regulator, receiver
BSY15_RS05175	COG3850	Histidine kinase
BSY15_RS05175	COG4999	Histidine kinase
BSY15_RS05180	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BSY15_RS05200	COG0783	Belongs to the Dps family
BSY15_RS05220	COG0583	DNA-binding transcription factor activity
BSY15_RS05235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BSY15_RS05250	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BSY15_RS05265	COG0583	DNA-binding transcription factor activity
BSY15_RS05275	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BSY15_RS05280	COG0134	indole-3-glycerol-phosphate synthase activity
BSY15_RS05285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BSY15_RS05290	COG1280	lysine exporter protein (LysE YggA)
BSY15_RS05295	COG0512	Glutamine amidotransferase of anthranilate synthase
BSY15_RS05320	COG0546	phosphoglycolate phosphatase activity
BSY15_RS05350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BSY15_RS05355	COG2967	ApaG domain
BSY15_RS05370	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BSY15_RS05415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BSY15_RS05425	COG0596	Alpha beta hydrolase
BSY15_RS05440	COG0659	secondary active sulfate transmembrane transporter activity
BSY15_RS05445	COG3012	SEC-C Motif Domain Protein
BSY15_RS05445	COG3318	Belongs to the UPF0149 family
BSY15_RS05450	COG0069	glutamate synthase activity
BSY15_RS05485	COG0840	transmembrane signaling receptor activity
BSY15_RS05500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BSY15_RS05505	COG1137	ATPase activity
BSY15_RS05515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BSY15_RS05525	COG0018	arginyl-trna synthetase
BSY15_RS05545	COG0583	DNA-binding transcription factor activity
BSY15_RS05550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BSY15_RS05560	COG1942	4-Oxalocrotonate Tautomerase
BSY15_RS05565	COG2814	Major facilitator Superfamily
BSY15_RS05575	COG2801	Transposase and inactivated derivatives
BSY15_RS05580	COG0121	glutamine amidotransferase
BSY15_RS05610	COG0189	ligase activity
BSY15_RS05615	COG3135	benzoate transporter
BSY15_RS05620	COG3158	transport of potassium into the cell
BSY15_RS05630	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BSY15_RS05635	COG0569	domain protein
BSY15_RS05640	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BSY15_RS05645	COG2194	sulfuric ester hydrolase activity
BSY15_RS05675	COG0495	leucyl-tRNA aminoacylation
BSY15_RS05690	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BSY15_RS05695	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BSY15_RS05700	COG0735	belongs to the Fur family
BSY15_RS05705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BSY15_RS05715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BSY15_RS05720	COG2814	Major facilitator Superfamily
BSY15_RS05725	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BSY15_RS05730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BSY15_RS05735	COG3118	belongs to the thioredoxin family
BSY15_RS05740	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BSY15_RS05745	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BSY15_RS05750	COG0009	L-threonylcarbamoyladenylate synthase
BSY15_RS05770	COG2027	D-alanyl-D-alanine carboxypeptidase
BSY15_RS05800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSY15_RS05805	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS05810	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BSY15_RS05815	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BSY15_RS05855	COG0006	proline dipeptidase activity
BSY15_RS05860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BSY15_RS05865	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BSY15_RS05870	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BSY15_RS05875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BSY15_RS05880	COG0668	transmembrane transport
BSY15_RS05895	COG0667	Aldo Keto reductase
BSY15_RS05910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY15_RS05915	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS05920	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY15_RS05925	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY15_RS05930	COG1309	transcriptional regulator
BSY15_RS05955	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS05965	COG2159	amidohydrolase
BSY15_RS05975	COG0583	DNA-binding transcription factor activity
BSY15_RS05980	COG3135	benzoate transporter
BSY15_RS05990	COG4829	muconolactone delta-isomerase
BSY15_RS05995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY15_RS06000	COG2814	Major facilitator Superfamily
BSY15_RS06025	COG3485	protocatechuate 3,4-dioxygenase
BSY15_RS06040	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS06060	COG4177	L-phenylalanine transmembrane transporter activity
BSY15_RS06090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BSY15_RS06100	COG1335	isochorismatase
BSY15_RS06105	COG0583	DNA-binding transcription factor activity
BSY15_RS06130	COG0745	RESPONSE REGULATOR receiver
BSY15_RS06135	COG1047	Peptidyl-prolyl cis-trans
BSY15_RS06180	COG0300	oxidoreductase activity
BSY15_RS06200	COG3148	PFAM DTW domain containing protein
BSY15_RS06215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY15_RS06230	COG2094	Belongs to the DNA glycosylase MPG family
BSY15_RS06235	COG2365	Tyrosine phosphatase family
BSY15_RS06255	COG1881	PFAM PEBP family protein
BSY15_RS06270	COG0551	DNA topoisomerase type I activity
BSY15_RS06270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSY15_RS06295	COG0642	Histidine kinase
BSY15_RS06310	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS06325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BSY15_RS06330	COG2137	regulation of response to DNA damage stimulus
BSY15_RS06335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BSY15_RS06340	COG0045	succinate-CoA ligase (ADP-forming) activity
BSY15_RS06345	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BSY15_RS06350	COG0515	serine threonine protein kinase
BSY15_RS06350	COG2815	serine threonine protein kinase
BSY15_RS06360	COG1716	ATPase activity
BSY15_RS06370	COG2801	Transposase and inactivated derivatives
BSY15_RS06375	COG0315	cyclic pyranopterin monophosphate synthase activity
BSY15_RS06380	COG4783	chaperone-mediated protein folding
BSY15_RS06385	COG1950	PFAM Membrane protein of
BSY15_RS06395	COG0861	Integral membrane protein TerC family
BSY15_RS06420	COG0625	glutathione transferase activity
BSY15_RS06430	COG0300	oxidoreductase activity
BSY15_RS06450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BSY15_RS06495	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BSY15_RS06530	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY15_RS06530	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY15_RS06535	COG2814	Major facilitator Superfamily
BSY15_RS06540	COG1522	sequence-specific DNA binding
BSY15_RS06550	COG1862	Preprotein translocase
BSY15_RS06555	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY15_RS06560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BSY15_RS06580	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BSY15_RS06595	COG0724	RNA recognition motif
BSY15_RS06600	COG0724	RNA recognition motif
BSY15_RS06605	COG2119	membrane
BSY15_RS06610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY15_RS06615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY15_RS06615	COG2813	Specifically methylates the guanine in position
BSY15_RS06625	COG3622	Belongs to the hyi family
BSY15_RS06640	COG2267	carboxylic ester hydrolase activity
BSY15_RS06690	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BSY15_RS06755	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY15_RS06760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY15_RS06765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BSY15_RS06775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BSY15_RS06815	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BSY15_RS06820	COG0163	prenyltransferase activity
BSY15_RS06830	COG3154	lipid carrier protein
BSY15_RS06835	COG1272	protein, Hemolysin III
BSY15_RS06840	COG0826	peptidase U32
BSY15_RS06845	COG0826	peptidase U32
BSY15_RS06850	COG2814	Major facilitator Superfamily
BSY15_RS06855	COG0482	sulfurtransferase activity
BSY15_RS06860	COG0629	single-stranded DNA binding
BSY15_RS06865	COG2814	Major facilitator Superfamily
BSY15_RS06920	COG3284	Transcriptional regulator
BSY15_RS06925	COG1012	belongs to the aldehyde dehydrogenase family
BSY15_RS06985	COG0583	DNA-binding transcription factor activity
BSY15_RS06990	COG0284	orotidine-5'-phosphate decarboxylase activity
BSY15_RS07005	COG0126	phosphoglycerate kinase activity
BSY15_RS07020	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BSY15_RS07030	COG0242	peptide deformylase activity
BSY15_RS07040	COG0758	DNA mediated transformation
BSY15_RS07050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BSY15_RS07060	COG2066	Belongs to the glutaminase family
BSY15_RS07060	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BSY15_RS07065	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BSY15_RS07070	COG0706	membrane insertase activity
BSY15_RS07075	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BSY15_RS07080	COG0594	ribonuclease P activity
BSY15_RS07085	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BSY15_RS07090	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BSY15_RS07165	COG1764	response to oxidative stress
BSY15_RS07170	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS07240	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BSY15_RS07245	COG1518	maintenance of DNA repeat elements
BSY15_RS07280	COG1199	ATP-dependent helicase activity
BSY15_RS07285	COG2824	Alkylphosphonate utilization operon protein PhnA
BSY15_RS07305	COG1199	ATP-dependent helicase activity
BSY15_RS07305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BSY15_RS07340	COG0791	NLP P60 protein
BSY15_RS07345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BSY15_RS07355	COG0789	Transcriptional regulator
BSY15_RS07370	COG2974	May be involved in recombination
BSY15_RS07375	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BSY15_RS07375	COG2755	lipolytic protein G-D-S-L family
BSY15_RS07445	COG1902	pentaerythritol trinitrate reductase activity
BSY15_RS07455	COG0625	glutathione transferase activity
BSY15_RS07465	COG0583	DNA-binding transcription factor activity
BSY15_RS07470	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY15_RS07475	COG3002	Belongs to the UPF0753 family
BSY15_RS07510	COG0445	tRNA wobble uridine modification
BSY15_RS07515	COG0357	Ribosomal RNA small subunit methyltransferase G
BSY15_RS07525	COG1192	Involved in chromosome partitioning
BSY15_RS07545	COG1475	DNA binding
BSY15_RS07555	COG2963	transposase activity
BSY15_RS07595	COG0596	Alpha beta hydrolase
BSY15_RS07600	COG5002	protein histidine kinase activity
BSY15_RS07600	COG5001	Diguanylate cyclase
BSY15_RS07630	COG1522	sequence-specific DNA binding
BSY15_RS07655	COG1201	RNA secondary structure unwinding
BSY15_RS07660	COG1793	dna ligase
BSY15_RS07665	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSY15_RS07665	COG1793	dna ligase
BSY15_RS07675	COG1742	UPF0060 membrane protein
BSY15_RS07680	COG3706	GGDEF domain
BSY15_RS07685	COG0277	FAD linked oxidase domain protein
BSY15_RS07695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BSY15_RS07700	COG0765	amino acid transport
BSY15_RS07705	COG0765	amino acid transport
BSY15_RS07710	COG1126	abc transporter atp-binding protein
BSY15_RS07725	COG2096	Adenosyltransferase
BSY15_RS07730	COG2050	protein possibly involved in aromatic compounds catabolism
BSY15_RS07740	COG2233	PERMEase
BSY15_RS07760	COG2249	NAD(P)H dehydrogenase (quinone) activity
BSY15_RS07795	COG0366	Alpha amylase catalytic
BSY15_RS07800	COG0366	Alpha amylase catalytic
BSY15_RS07805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BSY15_RS07815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY15_RS07825	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS07830	COG1183	phosphatidylcholine synthase activity
BSY15_RS07865	COG0850	regulation of cytokinetic process
BSY15_RS07875	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BSY15_RS07885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BSY15_RS07900	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSY15_RS07905	COG1309	transcriptional regulator
BSY15_RS07915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY15_RS07930	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY15_RS07935	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY15_RS07960	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BSY15_RS07965	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BSY15_RS07970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY15_RS07980	COG0724	RNA recognition motif
BSY15_RS07990	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS07995	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY15_RS08000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY15_RS08005	COG0277	FAD linked oxidase domain protein
BSY15_RS08025	COG0583	DNA-binding transcription factor activity
BSY15_RS08035	COG0037	tRNA processing
BSY15_RS08040	COG0826	peptidase U32
BSY15_RS08050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSY15_RS08055	COG2326	polyphosphate kinase activity
BSY15_RS08070	COG1410	methionine synthase
BSY15_RS08070	COG0646	methionine synthase
BSY15_RS08085	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BSY15_RS08155	COG0683	leucine binding
BSY15_RS08195	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS08215	COG1024	Enoyl-CoA hydratase
BSY15_RS08230	COG0606	chelatase, subunit chli
BSY15_RS08245	COG0004	ammonium transporteR
BSY15_RS08250	COG0277	FAD linked oxidase domain protein
BSY15_RS08260	COG0247	lactate metabolic process
BSY15_RS08300	COG0386	Belongs to the glutathione peroxidase family
BSY15_RS08320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BSY15_RS08340	COG0747	negative chemotaxis
BSY15_RS08345	COG0625	glutathione transferase activity
BSY15_RS08350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BSY15_RS08375	COG0438	transferase activity, transferring glycosyl groups
BSY15_RS08410	COG0477	Major facilitator Superfamily
BSY15_RS08415	COG2205	protein histidine kinase activity
BSY15_RS08420	COG0745	RESPONSE REGULATOR receiver
BSY15_RS08425	COG2211	Major facilitator Superfamily
BSY15_RS08440	COG2909	trisaccharide binding
BSY15_RS08445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY15_RS08450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSY15_RS08455	COG0708	Exodeoxyribonuclease III
BSY15_RS08460	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BSY15_RS08470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY15_RS08475	COG0154	amidase activity
BSY15_RS08480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BSY15_RS08485	COG1077	Cell shape determining protein MreB Mrl
BSY15_RS08495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BSY15_RS08500	COG0768	penicillin binding
BSY15_RS08520	COG0765	amino acid transport
BSY15_RS08525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY15_RS08540	COG0583	DNA-binding transcription factor activity
BSY15_RS08545	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BSY15_RS08550	COG1127	ABC transporter
BSY15_RS08595	COG4452	Inner membrane protein CreD
BSY15_RS08605	COG2205	protein histidine kinase activity
BSY15_RS08610	COG0745	RESPONSE REGULATOR receiver
BSY15_RS08615	COG2095	MarC family integral membrane protein
BSY15_RS08620	COG0412	Dienelactone hydrolase
BSY15_RS08635	COG0840	transmembrane signaling receptor activity
BSY15_RS08640	COG0598	Magnesium transport protein CorA
BSY15_RS08650	COG1981	membrane
BSY15_RS08665	COG2945	thiolester hydrolase activity
BSY15_RS08670	COG1686	Belongs to the peptidase S11 family
BSY15_RS08675	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BSY15_RS08680	COG0049	tRNA binding
BSY15_RS08685	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BSY15_RS08690	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY15_RS08695	COG0051	transcription antitermination factor activity, RNA binding
BSY15_RS08700	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BSY15_RS08705	COG0088	Forms part of the polypeptide exit tunnel
BSY15_RS08710	COG0089	rRNA binding
BSY15_RS08715	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BSY15_RS08720	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BSY15_RS08725	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BSY15_RS08730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BSY15_RS08735	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BSY15_RS08740	COG0255	Belongs to the universal ribosomal protein uL29 family
BSY15_RS08745	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BSY15_RS08750	COG0678	peroxiredoxin activity
BSY15_RS08765	COG3909	cytochrome
BSY15_RS08770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY15_RS08790	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BSY15_RS08795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BSY15_RS08810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BSY15_RS08815	COG0321	lipoyl(octanoyl) transferase activity
BSY15_RS08820	COG2921	Belongs to the UPF0250 family
BSY15_RS08830	COG0356	it plays a direct role in the translocation of protons across the membrane
BSY15_RS08840	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BSY15_RS08845	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BSY15_RS08850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BSY15_RS08855	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BSY15_RS08860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BSY15_RS08865	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BSY15_RS08915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY15_RS08920	COG1309	transcriptional regulator
BSY15_RS08945	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BSY15_RS08955	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BSY15_RS08965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BSY15_RS08970	COG0081	regulation of translation
BSY15_RS08980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BSY15_RS08985	COG0222	ribosome binding
BSY15_RS08990	COG0085	RNA polymerase activity
BSY15_RS08995	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BSY15_RS09005	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY15_RS09005	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSY15_RS09015	COG5000	phosphorelay sensor kinase activity
BSY15_RS09020	COG2204	response regulator
BSY15_RS09030	COG0443	Heat shock 70 kDa protein
BSY15_RS09035	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSY15_RS09040	COG0792	nuclease activity
BSY15_RS09045	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BSY15_RS09050	COG2823	Periplasmic or secreted lipoprotein
BSY15_RS09055	COG2084	Dehydrogenase
BSY15_RS09065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY15_RS09075	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BSY15_RS09085	COG4770	biotin carboxylase activity
BSY15_RS09095	COG2733	membrane
BSY15_RS09100	COG1346	cytolysis
BSY15_RS09105	COG1380	Effector of murein hydrolase LrgA
BSY15_RS09110	COG0277	FAD linked oxidase domain protein
BSY15_RS09115	COG0583	DNA-binding transcription factor activity
BSY15_RS09140	COG2197	response regulator
BSY15_RS09150	COG2223	nitrite transmembrane transporter activity
BSY15_RS09155	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BSY15_RS09160	COG1140	nitrate reductase beta subunit
BSY15_RS09165	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BSY15_RS09170	COG2181	nitrate reductase activity
BSY15_RS09175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY15_RS09180	COG0288	reversible hydration of carbon dioxide
BSY15_RS09185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY15_RS09205	COG3945	hemerythrin HHE cation binding domain
BSY15_RS09235	COG1979	alcohol dehydrogenase
BSY15_RS09250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSY15_RS09275	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BSY15_RS09280	COG4804	nuclease activity
BSY15_RS09290	COG0243	molybdopterin cofactor binding
BSY15_RS09305	COG1473	amidohydrolase
BSY15_RS09325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY15_RS09335	COG2423	ornithine cyclodeaminase activity
BSY15_RS09365	COG0431	NADPH-dependent FMN reductase
BSY15_RS09375	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSY15_RS09380	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BSY15_RS09385	COG1609	Transcriptional regulator
BSY15_RS09390	COG3624	Phosphonate C-P lyase system protein PhnG
BSY15_RS09400	COG3626	phosphonate metabolism
BSY15_RS09405	COG3627	carbon phosphorus lyase activity
BSY15_RS09415	COG4107	phosphonate C-P lyase system protein PhnK
BSY15_RS09420	COG4778	phosphonate C-P lyase system protein PhnL
BSY15_RS09425	COG3454	Phosphonate metabolism
BSY15_RS09430	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSY15_RS09435	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BSY15_RS09440	COG3639	organic phosphonate transmembrane transporter activity
BSY15_RS09455	COG0697	spore germination
BSY15_RS09460	COG0251	oxidation-reduction process
BSY15_RS09470	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS09475	COG1024	Enoyl-CoA hydratase
BSY15_RS09545	COG3267	Type II secretory pathway component ExeA
BSY15_RS09545	COG3409	Peptidoglycan-binding domain 1 protein
BSY15_RS09560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY15_RS09565	COG0840	transmembrane signaling receptor activity
BSY15_RS09585	COG1187	pseudouridine synthase activity
BSY15_RS09600	COG0326	Molecular chaperone. Has ATPase activity
BSY15_RS09615	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSY15_RS09625	COG2815	serine threonine protein kinase
BSY15_RS09625	COG0515	serine threonine protein kinase
BSY15_RS09635	COG1764	response to oxidative stress
BSY15_RS09640	COG1846	Transcriptional regulator
BSY15_RS09645	COG1024	Enoyl-CoA hydratase
BSY15_RS09650	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS09660	COG0842	Transport permease protein
BSY15_RS09665	COG3851	Histidine kinase
BSY15_RS09675	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY15_RS09680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS09685	COG1116	anion transmembrane transporter activity
BSY15_RS09685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY15_RS09690	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
BSY15_RS09700	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BSY15_RS09705	COG1131	(ABC) transporter
BSY15_RS09715	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BSY15_RS09725	COG0513	Belongs to the DEAD box helicase family
BSY15_RS09745	COG4191	Histidine kinase
BSY15_RS09750	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BSY15_RS09755	COG1490	D-aminoacyl-tRNA deacylase activity
BSY15_RS09765	COG0730	response to heat
BSY15_RS09770	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BSY15_RS09775	COG1702	phosphate starvation-inducible protein PhoH
BSY15_RS09780	COG0632	four-way junction helicase activity
BSY15_RS09790	COG2255	four-way junction helicase activity
BSY15_RS09800	COG4591	ABC-type transport system involved in lipoprotein release permease component
BSY15_RS09805	COG1136	(ABC) transporter
BSY15_RS09815	COG3616	Alanine racemase, N-terminal domain
BSY15_RS09830	COG0037	tRNA processing
BSY15_RS09840	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS09865	COG3118	belongs to the thioredoxin family
BSY15_RS09875	COG0617	tRNA 3'-terminal CCA addition
BSY15_RS09895	COG0745	RESPONSE REGULATOR receiver
BSY15_RS09900	COG5001	Diguanylate cyclase
BSY15_RS09900	COG3300	MHYT domain
BSY15_RS09905	COG0840	transmembrane signaling receptor activity
BSY15_RS09910	COG0745	RESPONSE REGULATOR receiver
BSY15_RS09915	COG0745	RESPONSE REGULATOR receiver
BSY15_RS09925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BSY15_RS09930	COG1196	nuclear chromosome segregation
BSY15_RS09930	COG0741	lytic transglycosylase activity
BSY15_RS09930	COG0739	heme binding
BSY15_RS09940	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS09955	COG3186	Phenylalanine-4-hydroxylase
BSY15_RS09970	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BSY15_RS09975	COG1522	sequence-specific DNA binding
BSY15_RS09990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BSY15_RS10005	COG0583	DNA-binding transcription factor activity
BSY15_RS10015	COG0752	glycyl-tRNA synthetase alpha subunit
BSY15_RS10020	COG0751	glycine-tRNA ligase activity
BSY15_RS10025	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BSY15_RS10045	COG1652	LysM domain
BSY15_RS10050	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BSY15_RS10070	COG4221	oxidoreductase activity
BSY15_RS10080	COG1091	dTDP-4-dehydrorhamnose reductase activity
BSY15_RS10085	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BSY15_RS10100	COG1216	Glycosyl transferase, family 2
BSY15_RS10105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BSY15_RS10110	COG1459	type II secretion system
BSY15_RS10135	COG3156	type II secretion system protein K
BSY15_RS10155	COG1450	Type ii and iii secretion system protein
BSY15_RS10210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BSY15_RS10220	COG1196	nuclear chromosome segregation
BSY15_RS10220	COG0741	lytic transglycosylase activity
BSY15_RS10220	COG0739	heme binding
BSY15_RS10230	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSY15_RS10235	COG0745	RESPONSE REGULATOR receiver
BSY15_RS10240	COG0642	Histidine kinase
BSY15_RS10245	COG1309	transcriptional regulator
BSY15_RS10255	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10265	COG1024	Enoyl-CoA hydratase
BSY15_RS10265	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS10275	COG0183	Belongs to the thiolase family
BSY15_RS10290	COG1024	Enoyl-CoA hydratase
BSY15_RS10300	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS10305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY15_RS10310	COG4335	DNA alkylation repair
BSY15_RS10315	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10320	COG1024	Enoyl-CoA hydratase
BSY15_RS10330	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10335	COG3246	L-lysine catabolic process to acetate
BSY15_RS10350	COG0183	Belongs to the thiolase family
BSY15_RS10360	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10385	COG1172	Belongs to the binding-protein-dependent transport system permease family
BSY15_RS10390	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY15_RS10410	COG5265	(ABC) transporter
BSY15_RS10415	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY15_RS10425	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS10430	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY15_RS10430	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY15_RS10440	COG0583	DNA-binding transcription factor activity
BSY15_RS10455	COG0765	amino acid transport
BSY15_RS10460	COG0765	amino acid transport
BSY15_RS10465	COG1126	abc transporter atp-binding protein
BSY15_RS10470	COG0418	dihydroorotase activity
BSY15_RS10480	COG0501	Belongs to the peptidase M48B family
BSY15_RS10490	COG1473	amidohydrolase
BSY15_RS10500	COG0583	DNA-binding transcription factor activity
BSY15_RS10505	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BSY15_RS10510	COG0392	lysyltransferase activity
BSY15_RS10520	COG3568	Endonuclease Exonuclease Phosphatase
BSY15_RS10550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY15_RS10555	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BSY15_RS10565	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSY15_RS10575	COG0840	transmembrane signaling receptor activity
BSY15_RS10580	COG0840	transmembrane signaling receptor activity
BSY15_RS10585	COG0835	chemotaxis
BSY15_RS10595	COG0523	cobalamin synthesis protein
BSY15_RS10610	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BSY15_RS10615	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BSY15_RS10620	COG2001	Belongs to the MraZ family
BSY15_RS10625	COG0275	rRNA processing
BSY15_RS10640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY15_RS10645	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BSY15_RS10650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BSY15_RS10655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BSY15_RS10660	COG0772	Belongs to the SEDS family
BSY15_RS10665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BSY15_RS10670	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSY15_RS10675	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY15_RS10680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BSY15_RS10690	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BSY15_RS10695	COG0840	transmembrane signaling receptor activity
BSY15_RS10700	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BSY15_RS10705	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BSY15_RS10710	COG0840	transmembrane signaling receptor activity
BSY15_RS10780	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BSY15_RS10785	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY15_RS10790	COG1765	OsmC-like protein
BSY15_RS10795	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BSY15_RS10815	COG1473	amidohydrolase
BSY15_RS10820	COG0747	negative chemotaxis
BSY15_RS10825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BSY15_RS10830	COG0444	Belongs to the ABC transporter superfamily
BSY15_RS10835	COG4608	Belongs to the ABC transporter superfamily
BSY15_RS10840	COG0737	Belongs to the 5'-nucleotidase family
BSY15_RS10845	COG0583	DNA-binding transcription factor activity
BSY15_RS10850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS10850	COG1024	Enoyl-CoA hydratase
BSY15_RS10855	COG0183	Belongs to the thiolase family
BSY15_RS10860	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10865	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS10870	COG1024	Enoyl-CoA hydratase
BSY15_RS10875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY15_RS10890	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS10915	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY15_RS10925	COG3842	ATPase activity
BSY15_RS10930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BSY15_RS10955	COG0297	glycogen (starch) synthase activity
BSY15_RS10960	COG1640	4-alpha-glucanotransferase
BSY15_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS11035	COG3045	CreA protein
BSY15_RS11040	COG1181	Belongs to the D-alanine--D-alanine ligase family
BSY15_RS11040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BSY15_RS11050	COG1132	(ABC) transporter
BSY15_RS11085	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY15_RS11090	COG0501	Belongs to the peptidase M48B family
BSY15_RS11095	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BSY15_RS11100	COG0575	Belongs to the CDS family
BSY15_RS11120	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSY15_RS11125	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BSY15_RS11135	COG0557	exoribonuclease II activity
BSY15_RS11145	COG3150	esterase
BSY15_RS11150	COG0515	serine threonine protein kinase
BSY15_RS11150	COG2815	serine threonine protein kinase
BSY15_RS11155	COG0772	Belongs to the SEDS family
BSY15_RS11160	COG0312	modulator of DNA gyrase
BSY15_RS11170	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BSY15_RS11180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BSY15_RS11190	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BSY15_RS11195	COG0511	ligase activity, forming carbon-carbon bonds
BSY15_RS11200	COG0439	Biotin carboxylase
BSY15_RS11205	COG2264	protein methyltransferase activity
BSY15_RS11215	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BSY15_RS11225	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BSY15_RS11255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BSY15_RS11260	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BSY15_RS11265	COG2943	transferase activity, transferring hexosyl groups
BSY15_RS11265	COG3416	Protein conserved in bacteria
BSY15_RS11270	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BSY15_RS11275	COG2204	response regulator
BSY15_RS11285	COG2205	protein histidine kinase activity
BSY15_RS11290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY15_RS11305	COG1024	Enoyl-CoA hydratase
BSY15_RS11320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY15_RS11330	COG0012	GTP binding
BSY15_RS11340	COG1238	metal cluster binding
BSY15_RS11350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSY15_RS11355	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BSY15_RS11360	COG0138	bifunctional purine biosynthesis protein purh
BSY15_RS11370	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BSY15_RS11375	COG1414	Transcriptional regulator
BSY15_RS11380	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BSY15_RS11400	COG0835	chemotaxis
BSY15_RS11405	COG0840	transmembrane signaling receptor activity
BSY15_RS11410	COG0643	Histidine kinase
BSY15_RS11410	COG0784	Response regulator, receiver
BSY15_RS11410	COG2198	Histidine kinase
BSY15_RS11420	COG0415	Belongs to the DNA photolyase family
BSY15_RS11425	COG1678	Uncharacterized ACR, COG1678
BSY15_RS11430	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BSY15_RS11435	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BSY15_RS11440	COG0540	Belongs to the ATCase OTCase family
BSY15_RS11455	COG4772	TonB-dependent receptor
BSY15_RS11460	COG3842	ATPase activity
BSY15_RS11465	COG1178	ABC-type Fe3 transport system permease component
BSY15_RS11475	COG5002	protein histidine kinase activity
BSY15_RS11475	COG2205	protein histidine kinase activity
BSY15_RS11475	COG0784	Response regulator, receiver
BSY15_RS11485	COG5006	permease, DMT superfamily
BSY15_RS11520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BSY15_RS11530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BSY15_RS11550	COG1414	Transcriptional regulator
BSY15_RS11560	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSY15_RS11565	COG0183	Belongs to the thiolase family
BSY15_RS11595	COG2860	membrane
BSY15_RS11605	COG1280	lysine exporter protein (LysE YggA)
BSY15_RS11620	COG0583	DNA-binding transcription factor activity
BSY15_RS11625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BSY15_RS11630	COG1040	competence protein
BSY15_RS11635	COG2226	methyltransferase
BSY15_RS11650	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BSY15_RS11655	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BSY15_RS11685	COG1612	heme a metabolic process
BSY15_RS11690	COG0109	protoheme IX farnesyltransferase activity
BSY15_RS11695	COG1999	signal sequence binding
BSY15_RS11700	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS11705	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY15_RS11710	COG1324	tolerance protein
BSY15_RS11725	COG0612	Peptidase, M16
BSY15_RS11730	COG0612	Peptidase, M16
BSY15_RS11735	COG0742	ribosomal rna small subunit methyltransferase
BSY15_RS11740	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BSY15_RS11745	COG0583	DNA-binding transcription factor activity
BSY15_RS11755	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSY15_RS11760	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BSY15_RS11775	COG0588	phosphoglycerate mutase activity
BSY15_RS11780	COG0793	Belongs to the peptidase S41A family
BSY15_RS11785	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BSY15_RS11795	COG2197	response regulator
BSY15_RS11825	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BSY15_RS11830	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BSY15_RS11840	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BSY15_RS11870	COG2197	response regulator
BSY15_RS11875	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BSY15_RS11880	COG0720	synthase
BSY15_RS11885	COG0602	queuosine metabolic process
BSY15_RS11890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BSY15_RS11920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY15_RS11920	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY15_RS11940	COG0489	protein tyrosine kinase activity
BSY15_RS11945	COG0583	DNA-binding transcription factor activity
BSY15_RS11955	COG3383	formate dehydrogenase (NAD+) activity
BSY15_RS11985	COG0243	molybdopterin cofactor binding
BSY15_RS11985	COG3383	formate dehydrogenase (NAD+) activity
BSY15_RS11990	COG0437	4 iron, 4 sulfur cluster binding
BSY15_RS12010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BSY15_RS12020	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BSY15_RS12025	COG2346	COG2346, Truncated hemoglobins
BSY15_RS12035	COG1193	negative regulation of DNA recombination
BSY15_RS12045	COG2003	Belongs to the UPF0758 family
BSY15_RS12050	COG1047	Peptidyl-prolyl cis-trans
BSY15_RS12055	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BSY15_RS12060	COG3039	Transposase
BSY15_RS12065	COG0517	IMP dehydrogenase activity
BSY15_RS12065	COG0617	tRNA 3'-terminal CCA addition
BSY15_RS12065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BSY15_RS12070	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BSY15_RS12075	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BSY15_RS12080	COG0709	Synthesizes selenophosphate from selenide and ATP
BSY15_RS12085	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BSY15_RS12140	COG0514	ATP-dependent DNA helicase (RecQ)
BSY15_RS12150	COG1431	PFAM Stem cell self-renewal protein Piwi
BSY15_RS12155	COG0494	nUDIX hydrolase
BSY15_RS12165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSY15_RS12170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY15_RS12205	COG3339	Conserved Protein
BSY15_RS12220	COG0583	DNA-binding transcription factor activity
BSY15_RS12225	COG2801	Transposase and inactivated derivatives
BSY15_RS12230	COG2801	Transposase and inactivated derivatives
BSY15_RS12260	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BSY15_RS12285	COG0583	DNA-binding transcription factor activity
BSY15_RS12300	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BSY15_RS12315	COG0745	RESPONSE REGULATOR receiver
BSY15_RS12320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY15_RS12330	COG0180	Tryptophanyl-tRNA synthetase
BSY15_RS12335	COG1994	Peptidase M50
BSY15_RS12340	COG0840	transmembrane signaling receptor activity
BSY15_RS12345	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BSY15_RS12345	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BSY15_RS12355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BSY15_RS12360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BSY15_RS12365	COG0492	ferredoxin-NADP+ reductase activity
BSY15_RS12370	COG1674	ftsk spoiiie
BSY15_RS12375	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BSY15_RS12380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BSY15_RS12385	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY15_RS12410	COG1392	Phosphate transport regulator
BSY15_RS12415	COG0306	phosphate transporter
BSY15_RS12430	COG0228	four-way junction DNA binding
BSY15_RS12435	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BSY15_RS12440	COG0336	Belongs to the RNA methyltransferase TrmD family
BSY15_RS12445	COG0335	large ribosomal subunit rRNA binding
BSY15_RS12450	COG0494	nUDIX hydrolase
BSY15_RS12455	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BSY15_RS12460	COG1162	GTPase activity
BSY15_RS12465	COG2154	pterin-4-alpha-carbinolamine dehydratase
BSY15_RS12470	COG0501	Belongs to the peptidase M48B family
BSY15_RS12475	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BSY15_RS12480	COG0513	Belongs to the DEAD box helicase family
BSY15_RS12485	COG3447	MASE1 domain protein
BSY15_RS12485	COG5001	Diguanylate cyclase
BSY15_RS12485	COG5002	protein histidine kinase activity
BSY15_RS12490	COG2814	Major facilitator Superfamily
BSY15_RS12500	COG2084	Dehydrogenase
BSY15_RS12510	COG0516	GMP reductase activity
BSY15_RS12520	COG0210	DNA helicase
BSY15_RS12535	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BSY15_RS12560	COG0625	glutathione transferase activity
BSY15_RS12575	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY15_RS12580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BSY15_RS12600	COG0412	Dienelactone hydrolase
BSY15_RS12620	COG3275	phosphorelay sensor kinase activity
BSY15_RS12625	COG0165	Argininosuccinate lyase
BSY15_RS12635	COG0753	catalase activity
BSY15_RS12645	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BSY15_RS12650	COG5002	protein histidine kinase activity
BSY15_RS12650	COG5001	Diguanylate cyclase
BSY15_RS12650	COG3447	MASE1 domain protein
BSY15_RS12655	COG1304	FMN binding
BSY15_RS12665	COG1595	DNA-templated transcription, initiation
BSY15_RS12720	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY15_RS12725	COG0840	transmembrane signaling receptor activity
BSY15_RS12730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSY15_RS12730	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BSY15_RS12740	COG3022	response to hydroperoxide
BSY15_RS12745	COG1530	ribonuclease E activity
BSY15_RS12765	COG0616	signal peptide processing
BSY15_RS12765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BSY15_RS12770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BSY15_RS12775	COG0424	maF-like protein
BSY15_RS12780	COG1399	metal-binding, possibly nucleic acid-binding protein
BSY15_RS12785	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BSY15_RS12790	COG0416	fatty acid biosynthetic process
BSY15_RS12795	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BSY15_RS12805	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS12810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BSY15_RS12815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BSY15_RS12840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BSY15_RS12845	COG0481	GTPase activity
BSY15_RS12850	COG0681	Belongs to the peptidase S26 family
BSY15_RS12860	COG0571	ribonuclease III activity
BSY15_RS12865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BSY15_RS12870	COG1381	Involved in DNA repair and RecF pathway recombination
BSY15_RS12875	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BSY15_RS12880	COG0736	holo-[acyl-carrier-protein] synthase activity
BSY15_RS12895	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BSY15_RS12900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BSY15_RS12905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BSY15_RS12950	COG0762	integral membrane protein
BSY15_RS12955	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BSY15_RS12960	COG0159	tryptophan synthase activity
BSY15_RS12965	COG0133	tryptophan synthase activity
BSY15_RS12970	COG0135	phosphoribosylanthranilate isomerase activity
BSY15_RS12975	COG0101	tRNA pseudouridine synthase activity
BSY15_RS12985	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BSY15_RS12995	COG0473	3-isopropylmalate dehydrogenase activity
BSY15_RS13000	COG0066	3-isopropylmalate dehydratase activity
BSY15_RS13010	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BSY15_RS13020	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BSY15_RS13025	COG0484	heat shock protein binding
BSY15_RS13030	COG0443	Heat shock 70 kDa protein
BSY15_RS13035	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BSY15_RS13040	COG0360	Binds together with S18 to 16S ribosomal RNA
BSY15_RS13050	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BSY15_RS13055	COG0359	binds to the 23S rRNA
BSY15_RS13070	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BSY15_RS13075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BSY15_RS13085	COG0436	Aminotransferase
BSY15_RS13110	COG1763	Mo-molybdopterin cofactor biosynthetic process
BSY15_RS13125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY15_RS13145	COG0314	molybdopterin synthase activity
BSY15_RS13150	COG0542	response to heat
BSY15_RS13170	COG2264	protein methyltransferase activity
BSY15_RS13185	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BSY15_RS13190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BSY15_RS13200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY15_RS13200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BSY15_RS13220	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BSY15_RS13225	COG1185	polyribonucleotide nucleotidyltransferase activity
BSY15_RS13230	COG3321	synthase
BSY15_RS13230	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS13230	COG0604	alcohol dehydrogenase
BSY15_RS13235	COG0149	triose-phosphate isomerase activity
BSY15_RS13250	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY15_RS13255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY15_RS13260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY15_RS13265	COG0649	NAD binding
BSY15_RS13270	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BSY15_RS13275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BSY15_RS13280	COG1034	ATP synthesis coupled electron transport
BSY15_RS13285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BSY15_RS13290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BSY15_RS13300	COG0713	ATP synthesis coupled electron transport
BSY15_RS13315	COG1007	ATP synthesis coupled electron transport
BSY15_RS13330	COG1132	(ABC) transporter
BSY15_RS13350	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY15_RS13390	COG0071	Belongs to the small heat shock protein (HSP20) family
BSY15_RS13395	COG4181	ATPase activity
BSY15_RS13400	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BSY15_RS13405	COG2814	Major facilitator Superfamily
BSY15_RS13410	COG2267	carboxylic ester hydrolase activity
BSY15_RS13420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BSY15_RS13425	COG0584	glycerophosphoryl diester phosphodiesterase
BSY15_RS13430	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BSY15_RS13435	COG0586	Pfam SNARE associated Golgi protein
BSY15_RS13445	COG0840	transmembrane signaling receptor activity
BSY15_RS13450	COG0860	N-Acetylmuramoyl-L-alanine amidase
BSY15_RS13455	COG0802	atpase or kinase
BSY15_RS13460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BSY15_RS13480	COG4974	Belongs to the 'phage' integrase family
BSY15_RS13485	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS13490	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BSY15_RS13495	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BSY15_RS13500	COG2833	Protein of unknown function (DUF455)
BSY15_RS13510	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BSY15_RS13525	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BSY15_RS13530	COG0148	phosphopyruvate hydratase activity
BSY15_RS13540	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BSY15_RS13545	COG0504	CTP synthase activity
BSY15_RS13550	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BSY15_RS13560	COG0756	dUTP diphosphatase activity
BSY15_RS13570	COG1047	Peptidyl-prolyl cis-trans
BSY15_RS13575	COG2850	peptidyl-arginine hydroxylation
BSY15_RS13595	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BSY15_RS13600	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BSY15_RS13620	COG0741	lytic transglycosylase activity
BSY15_RS13645	COG2308	Evidence 4 Homologs of previously reported genes of
BSY15_RS13655	COG4628	conserved protein (DUF2132)
BSY15_RS13665	COG0657	acetylesterase activity
BSY15_RS13670	COG0436	Aminotransferase
BSY15_RS13685	COG0861	Integral membrane protein TerC family
BSY15_RS13695	COG0672	)-iron permease
BSY15_RS13705	COG3634	alkyl hydroperoxide reductase activity
BSY15_RS13710	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY15_RS13715	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BSY15_RS13730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BSY15_RS13750	COG0583	DNA-binding transcription factor activity
BSY15_RS13755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY15_RS13760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY15_RS13770	COG0840	transmembrane signaling receptor activity
BSY15_RS13780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BSY15_RS13785	COG0358	DNA primase activity
BSY15_RS13790	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS13825	COG3540	Alkaline phosphatase
BSY15_RS13835	COG3321	synthase
BSY15_RS13835	COG0604	alcohol dehydrogenase
BSY15_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS13840	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BSY15_RS13845	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY15_RS13855	COG0564	pseudouridine synthase activity
BSY15_RS13860	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BSY15_RS13865	COG1187	pseudouridine synthase activity
BSY15_RS13870	COG0105	UTP biosynthetic process
BSY15_RS13875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BSY15_RS13890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BSY15_RS13895	COG0124	histidyl-tRNA synthetase
BSY15_RS13905	COG1160	GTP binding
BSY15_RS13910	COG1923	regulation of RNA biosynthetic process
BSY15_RS13915	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BSY15_RS13920	COG0330	HflC and HflK could
BSY15_RS13925	COG0330	HflC and HflK could
BSY15_RS13930	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BSY15_RS13935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BSY15_RS13970	COG1187	pseudouridine synthase activity
BSY15_RS14000	COG0174	glutamine synthetase
BSY15_RS14010	COG3852	Histidine kinase
BSY15_RS14025	COG0708	Exodeoxyribonuclease III
BSY15_RS14040	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BSY15_RS14050	COG1175	transmembrane transport
BSY15_RS14055	COG0395	ABC-type sugar transport system, permease component
BSY15_RS14070	COG0246	Mannitol dehydrogenase
BSY15_RS14075	COG2207	Transcriptional regulator
BSY15_RS14080	COG1070	Carbohydrate kinase
BSY15_RS14095	COG0277	FAD linked oxidase domain protein
BSY15_RS14105	COG1295	ribonuclease BN
BSY15_RS14115	COG2267	carboxylic ester hydrolase activity
BSY15_RS14135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BSY15_RS14145	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BSY15_RS14150	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BSY15_RS14155	COG0741	lytic transglycosylase activity
BSY15_RS14175	COG0557	exoribonuclease II activity
BSY15_RS14180	COG2267	carboxylic ester hydrolase activity
BSY15_RS14190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BSY15_RS14190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BSY15_RS14195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY15_RS14205	COG0052	Belongs to the universal ribosomal protein uS2 family
BSY15_RS14210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BSY15_RS14215	COG0528	UMP kinase activity
BSY15_RS14220	COG0233	cytoplasmic translational termination
BSY15_RS14225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BSY15_RS14235	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BSY15_RS14240	COG0750	zinc metalloprotease
BSY15_RS14255	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY15_RS14260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BSY15_RS14265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY15_RS14270	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BSY15_RS14275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BSY15_RS14280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY15_RS14285	COG0505	Belongs to the CarA family
BSY15_RS14295	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BSY15_RS14300	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BSY15_RS14315	COG1534	Rna-binding protein
BSY15_RS14320	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BSY15_RS14325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BSY15_RS14335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BSY15_RS14370	COG0573	inorganic phosphate transmembrane transporter activity
BSY15_RS14375	COG0581	inorganic phosphate transmembrane transporter activity
BSY15_RS14380	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BSY15_RS14390	COG0745	RESPONSE REGULATOR receiver
BSY15_RS14400	COG0534	Mate efflux family protein
BSY15_RS14410	COG0254	rRNA binding
BSY15_RS14415	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BSY15_RS14430	COG1074	ATP-dependent DNA helicase activity
BSY15_RS14435	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BSY15_RS14450	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BSY15_RS14455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BSY15_RS14470	COG1388	LysM domain
BSY15_RS14470	COG0741	lytic transglycosylase activity
BSY15_RS14475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BSY15_RS14480	COG2226	methyltransferase
BSY15_RS14485	COG0328	RNA-DNA hybrid ribonuclease activity
BSY15_RS14490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BSY15_RS14495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BSY15_RS14520	COG0303	'Molybdopterin
BSY15_RS14530	COG0746	molybdenum cofactor guanylyltransferase activity
BSY15_RS14535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BSY15_RS14580	COG0784	Response regulator, receiver
BSY15_RS14580	COG2205	protein histidine kinase activity
BSY15_RS14580	COG5002	protein histidine kinase activity
BSY15_RS14590	COG3437	response regulator, receiver
BSY15_RS14605	COG1858	cytochrome C peroxidase
BSY15_RS14630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BSY15_RS14645	COG0596	Alpha beta hydrolase
BSY15_RS14645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BSY15_RS14645	COG2226	methyltransferase
BSY15_RS14650	COG0840	transmembrane signaling receptor activity
BSY15_RS14670	COG0347	Belongs to the P(II) protein family
BSY15_RS14675	COG0640	Transcriptional regulator
BSY15_RS14695	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BSY15_RS14720	COG0028	Belongs to the TPP enzyme family
BSY15_RS14725	COG0440	acetolactate synthase activity
BSY15_RS14730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BSY15_RS14735	COG1183	phosphatidylcholine synthase activity
BSY15_RS14740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY15_RS14750	COG1414	Transcriptional regulator
BSY15_RS14755	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BSY15_RS14760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BSY15_RS14775	COG2832	Protein of unknown function (DUF454)
BSY15_RS14780	COG0242	peptide deformylase activity
BSY15_RS14785	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BSY15_RS14795	COG0047	phosphoribosylformylglycinamidine synthase activity
BSY15_RS14795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BSY15_RS14800	COG2264	protein methyltransferase activity
BSY15_RS14805	COG2354	Protein conserved in bacteria
BSY15_RS14810	COG3047	cAMP biosynthetic process
BSY15_RS14820	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BSY15_RS14825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BSY15_RS14835	COG2205	protein histidine kinase activity
BSY15_RS14840	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BSY15_RS14845	COG0826	peptidase U32
BSY15_RS14865	COG1619	proteins homologs of microcin C7 resistance protein MccF
BSY15_RS14915	COG1024	Enoyl-CoA hydratase
BSY15_RS14920	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS14935	COG2022	thiamine diphosphate biosynthetic process
BSY15_RS14950	COG0351	phosphomethylpyrimidine kinase
BSY15_RS14965	COG0492	ferredoxin-NADP+ reductase activity
BSY15_RS14970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BSY15_RS14980	COG0175	sulfate reduction
BSY15_RS15000	COG0730	response to heat
BSY15_RS15005	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BSY15_RS15005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BSY15_RS15010	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BSY15_RS15015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSY15_RS15020	COG0431	NADPH-dependent FMN reductase
BSY15_RS15025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY15_RS15030	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY15_RS15040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS15045	COG1116	anion transmembrane transporter activity
BSY15_RS15055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BSY15_RS15060	COG2175	clavaminate synthase activity
BSY15_RS15070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS15075	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS15085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BSY15_RS15090	COG3119	arylsulfatase activity
BSY15_RS15095	COG0583	DNA-binding transcription factor activity
BSY15_RS15110	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BSY15_RS15140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY15_RS15155	COG1595	DNA-templated transcription, initiation
BSY15_RS15165	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BSY15_RS15195	COG2814	Major facilitator Superfamily
BSY15_RS15200	COG0798	PFAM Bile acid sodium symporter
BSY15_RS15215	COG0456	acetyltransferase
BSY15_RS15235	COG0583	DNA-binding transcription factor activity
BSY15_RS15260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BSY15_RS15265	COG0583	DNA-binding transcription factor activity
BSY15_RS15280	COG0840	transmembrane signaling receptor activity
BSY15_RS15295	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BSY15_RS15305	COG4208	sulfate ABC transporter
BSY15_RS15310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BSY15_RS15315	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BSY15_RS15335	COG1054	Belongs to the UPF0176 family
BSY15_RS15355	COG3842	ATPase activity
BSY15_RS15360	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY15_RS15370	COG3842	ATPase activity
BSY15_RS15375	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BSY15_RS15380	COG0840	transmembrane signaling receptor activity
BSY15_RS15400	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BSY15_RS15400	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BSY15_RS15405	COG1643	Atp-dependent helicase
BSY15_RS15415	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS15435	COG0589	response to stress
BSY15_RS15440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSY15_RS15450	COG0183	Belongs to the thiolase family
BSY15_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS15460	COG0564	pseudouridine synthase activity
BSY15_RS15485	COG0545	Peptidyl-prolyl cis-trans isomerase
BSY15_RS15505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY15_RS15505	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BSY15_RS15510	COG0509	glycine decarboxylation via glycine cleavage system
BSY15_RS15515	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BSY15_RS15520	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BSY15_RS15520	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BSY15_RS15530	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS15540	COG0776	regulation of translation
BSY15_RS15550	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BSY15_RS15555	COG0287	Prephenate dehydrogenase
BSY15_RS15560	COG0077	Prephenate dehydratase
BSY15_RS15560	COG1605	Chorismate mutase
BSY15_RS15565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BSY15_RS15580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BSY15_RS15615	COG0745	RESPONSE REGULATOR receiver
BSY15_RS15620	COG2205	protein histidine kinase activity
BSY15_RS15625	COG2358	TRAP transporter, solute receptor (TAXI family
BSY15_RS15630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BSY15_RS15645	COG2986	histidine ammonia-lyase
BSY15_RS15650	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BSY15_RS15660	COG1228	amidohydrolase
BSY15_RS15680	COG0688	phosphatidylethanolamine metabolic process
BSY15_RS15705	COG1280	lysine exporter protein (LysE YggA)
BSY15_RS15720	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BSY15_RS15735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY15_RS15740	COG2917	probably involved in intracellular septation
BSY15_RS15745	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY15_RS15750	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BSY15_RS15755	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BSY15_RS15760	COG0318	PFAM AMP-dependent synthetase and ligase
BSY15_RS15770	COG0559	Belongs to the binding-protein-dependent transport system permease family
BSY15_RS15780	COG0411	ABC transporter
BSY15_RS15790	COG1024	Enoyl-CoA hydratase
BSY15_RS15790	COG1250	3-hydroxyacyl-CoA dehydrogenase
BSY15_RS15795	COG0183	Belongs to the thiolase family
BSY15_RS15815	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS15825	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS15835	COG2130	NADP-dependent
BSY15_RS15840	COG2153	protein acetylation
BSY15_RS15845	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS15860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BSY15_RS15865	COG2203	Gaf domain
BSY15_RS15865	COG5001	Diguanylate cyclase
BSY15_RS15865	COG3706	GGDEF domain
BSY15_RS15865	COG4251	negative regulation of phosphorylation
BSY15_RS15880	COG2183	response to ionizing radiation
BSY15_RS15905	COG0657	acetylesterase activity
BSY15_RS15920	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BSY15_RS15925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BSY15_RS15930	COG0470	DNA polymerase III
BSY15_RS15940	COG0084	hydrolase, TatD family'
BSY15_RS15950	COG1132	(ABC) transporter
BSY15_RS15955	COG0823	Involved in the tonB-independent uptake of proteins
BSY15_RS15970	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BSY15_RS16010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY15_RS16015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY15_RS16060	COG3328	transposase activity
BSY15_RS16100	COG5377	YqaJ viral recombinase family
BSY15_RS16145	COG0789	Transcriptional regulator
BSY15_RS16150	COG4372	Transposase
BSY15_RS16175	COG1024	Enoyl-CoA hydratase
BSY15_RS16180	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY15_RS16200	COG1022	Amp-dependent synthetase and ligase
BSY15_RS16225	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS16295	COG2801	Transposase and inactivated derivatives
BSY15_RS16325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY15_RS16330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY15_RS16340	COG0628	permease
BSY15_RS16345	COG0567	Dehydrogenase, E1 component
BSY15_RS16350	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY15_RS16355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY15_RS16360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BSY15_RS16370	COG0631	protein serine/threonine phosphatase activity
BSY15_RS16375	COG1199	ATP-dependent helicase activity
BSY15_RS16390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BSY15_RS16395	COG0542	response to heat
BSY15_RS16400	COG2951	lytic endotransglycosylase activity
BSY15_RS16405	COG2925	Exonuclease
BSY15_RS16410	COG0626	cystathionine gamma-synthase activity
BSY15_RS16415	COG0700	Nucleoside recognition
BSY15_RS16420	COG0217	transcriptional regulatory protein
BSY15_RS16425	COG0484	heat shock protein binding
BSY15_RS16450	COG3706	GGDEF domain
BSY15_RS16455	COG0402	S-adenosylhomocysteine deaminase activity
BSY15_RS16460	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BSY15_RS16480	COG0433	COG0433 Predicted ATPase
BSY15_RS16485	COG0217	transcriptional regulatory protein
BSY15_RS16490	COG0151	Belongs to the GarS family
BSY15_RS16495	COG0408	coproporphyrinogen oxidase activity
BSY15_RS16500	COG0799	negative regulation of ribosome biogenesis
BSY15_RS16505	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BSY15_RS16510	COG0424	maF-like protein
BSY15_RS16515	COG1530	ribonuclease E activity
BSY15_RS16525	COG0436	Aminotransferase
BSY15_RS16530	COG0583	DNA-binding transcription factor activity
BSY15_RS16550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BSY15_RS16570	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BSY15_RS16580	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BSY15_RS16585	COG0252	asparaginase activity
BSY15_RS16600	COG0563	adenylate kinase activity
BSY15_RS16605	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BSY15_RS16610	COG2835	tetraacyldisaccharide 4'-kinase activity
BSY15_RS16615	COG1663	tetraacyldisaccharide 4'-kinase activity
BSY15_RS16615	COG2835	tetraacyldisaccharide 4'-kinase activity
BSY15_RS16620	COG0848	biopolymer transport protein
BSY15_RS16625	COG0811	peptide transport
BSY15_RS16630	COG1570	exodeoxyribonuclease VII activity
BSY15_RS16635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BSY15_RS16680	COG1960	acyl-CoA dehydrogenase activity
BSY15_RS16695	COG0583	DNA-binding transcription factor activity
BSY15_RS16730	COG1132	(ABC) transporter
BSY15_RS16750	COG1196	nuclear chromosome segregation
BSY15_RS16760	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BSY15_RS16800	COG3243	poly(R)-hydroxyalkanoic acid synthase
BSY15_RS16805	COG0183	Belongs to the thiolase family
BSY15_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS16820	COG0488	(ABC) transporter
BSY15_RS16825	COG2890	protein-(glutamine-N5) methyltransferase activity
BSY15_RS16830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BSY15_RS16840	COG2171	N-acyltransferase activity
BSY15_RS16850	COG0840	transmembrane signaling receptor activity
BSY15_RS16855	COG2878	Part of a membrane complex involved in electron transport
BSY15_RS16880	COG0204	Acyl-transferase
BSY15_RS16885	COG1022	Amp-dependent synthetase and ligase
BSY15_RS16890	COG1802	Transcriptional regulator
BSY15_RS16895	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSY15_RS16895	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BSY15_RS16900	COG1703	isobutyryl-CoA mutase activity
BSY15_RS16905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BSY15_RS16910	COG4770	biotin carboxylase activity
BSY15_RS16920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BSY15_RS16945	COG0640	Transcriptional regulator
BSY15_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS16995	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BSY15_RS17025	COG4372	Transposase
BSY15_RS17035	COG0840	transmembrane signaling receptor activity
BSY15_RS17040	COG3039	Transposase
BSY15_RS17045	COG3328	transposase activity
BSY15_RS17090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BSY15_RS17155	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
BSY15_RS17165	COG1017	nitric oxide dioxygenase activity
BSY15_RS17165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BSY15_RS17170	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BSY15_RS17175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY15_RS17190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY15_RS17205	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY15_RS17215	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY15_RS17245	COG1012	belongs to the aldehyde dehydrogenase family
BSY15_RS17255	COG0583	DNA-binding transcription factor activity
BSY15_RS17270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY15_RS17295	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BSY15_RS17310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY15_RS17380	COG0789	Transcriptional regulator
BSY15_RS17390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BSY15_RS17425	COG0625	glutathione transferase activity
BSY15_RS17435	COG1309	transcriptional regulator
BSY15_RS17440	COG0625	glutathione transferase activity
BSY15_RS17450	COG2963	transposase activity
BSY15_RS17470	COG0346	lactoylglutathione lyase activity
BSY15_RS17485	COG2032	superoxide dismutase activity
BSY15_RS17490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BSY15_RS17495	COG0789	Transcriptional regulator
BSY15_RS17505	COG4221	oxidoreductase activity
BSY15_RS17525	COG1309	transcriptional regulator
BSY15_RS17530	COG0259	pyridoxamine-phosphate oxidase activity
BSY15_RS17555	COG5002	protein histidine kinase activity
BSY15_RS17585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BSY15_RS17595	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BSY15_RS17600	COG1309	transcriptional regulator
BSY15_RS17615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BSY15_RS17625	COG1538	Outer membrane efflux protein
BSY15_RS17640	COG3976	FMN-binding domain protein
BSY15_RS17640	COG1053	succinate dehydrogenase
BSY15_RS17695	COG0583	DNA-binding transcription factor activity
BSY15_RS17705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BSY15_RS17730	COG1040	competence protein
BSY15_RS17735	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BSY15_RS17745	COG2133	pyrroloquinoline quinone binding
BSY15_RS17750	COG0791	NLP P60 protein
BSY15_RS17805	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BSY15_RS17810	COG3145	DNA-N1-methyladenine dioxygenase activity
BSY15_RS17825	COG4566	intracellular signal transduction
BSY15_RS17850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BSY15_RS17855	COG2366	antibiotic biosynthetic process
BSY15_RS17860	COG0527	aspartate kinase activity
BSY15_RS17870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY15_RS17875	COG0508	dehydrogenase complex catalyzes the overall conversion of
BSY15_RS17880	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BSY15_RS17890	COG4566	intracellular signal transduction
BSY15_RS17895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BSY15_RS17910	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BSY15_RS17915	COG0167	dihydroorotate dehydrogenase activity
BSY15_RS17935	COG0579	oxidoreductase
BSY15_RS17965	COG0443	Heat shock 70 kDa protein
BSY15_RS17975	COG0316	Belongs to the HesB IscA family
BSY15_RS17980	COG0822	iron-sulfur transferase activity
BSY15_RS17985	COG1104	cysteine desulfurase activity
BSY15_RS17990	COG1959	2 iron, 2 sulfur cluster binding
BSY15_RS17995	COG0556	nucleotide-excision repair
BSY15_RS18010	COG3384	dioxygenase
BSY15_RS18015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY15_RS18030	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS18040	COG0583	DNA-binding transcription factor activity
BSY15_RS18075	COG1739	Uncharacterized protein family UPF0029
BSY15_RS18080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BSY15_RS18115	COG0583	DNA-binding transcription factor activity
BSY15_RS18135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BSY15_RS18140	COG4181	ATPase activity
BSY15_RS18180	COG1054	Belongs to the UPF0176 family
BSY15_RS18185	COG1741	Belongs to the pirin family
BSY15_RS18195	COG1741	Belongs to the pirin family
BSY15_RS18200	COG0583	DNA-binding transcription factor activity
BSY15_RS18210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY15_RS18215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BSY15_RS18225	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BSY15_RS18230	COG1012	belongs to the aldehyde dehydrogenase family
BSY15_RS18430	COG5484	DNA packaging
BSY15_RS18430	COG3728	DNA packaging
BSY15_RS18465	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BSY15_RS18570	COG2974	May be involved in recombination
BSY15_RS18585	COG0756	dUTP diphosphatase activity
BSY15_RS18795	COG5484	DNA packaging
BSY15_RS18795	COG3728	DNA packaging
BSY15_RS18830	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BSY15_RS18935	COG2974	May be involved in recombination
BSY15_RS18950	COG0756	dUTP diphosphatase activity
BSY15_RS18970	COG0840	transmembrane signaling receptor activity
BSY15_RS18980	COG2982	Protein involved in outer membrane biogenesis
BSY15_RS18985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BSY15_RS19000	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BSY15_RS19005	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BSY15_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS19030	COG0840	transmembrane signaling receptor activity
BSY15_RS19055	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BSY15_RS19060	COG4336	lyase activity
BSY15_RS19065	COG0583	DNA-binding transcription factor activity
BSY15_RS19075	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BSY15_RS19085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BSY15_RS19085	COG2111	Na H antiporter
BSY15_RS19090	COG1006	Multisubunit Na H antiporter MnhC subunit
BSY15_RS19095	COG0651	ATP synthesis coupled electron transport
BSY15_RS19100	COG1863	multisubunit Na H antiporter MnhE subunit
BSY15_RS19105	COG2212	antiporter activity
BSY15_RS19140	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BSY15_RS19175	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BSY15_RS19185	COG0123	including yeast histone deacetylase and acetoin utilization protein
BSY15_RS19195	COG1840	ABC-type Fe3 transport system, periplasmic component
BSY15_RS19240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BSY15_RS19250	COG1286	toxin biosynthetic process
BSY15_RS19260	COG0285	dihydrofolate synthase activity
BSY15_RS19265	COG1393	Belongs to the ArsC family
BSY15_RS19275	COG3123	guanosine phosphorylase activity
BSY15_RS19280	COG0137	argininosuccinate synthase activity
BSY15_RS19290	COG2198	Histidine kinase
BSY15_RS19290	COG2205	protein histidine kinase activity
BSY15_RS19290	COG0784	Response regulator, receiver
BSY15_RS19295	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BSY15_RS19300	COG1666	GTP binding
BSY15_RS19305	COG3577	Aspartyl protease
BSY15_RS19315	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BSY15_RS19320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BSY15_RS19325	COG0583	DNA-binding transcription factor activity
BSY15_RS19330	COG3181	Tripartite tricarboxylate transporter family receptor
BSY15_RS19340	COG0667	Aldo Keto reductase
BSY15_RS19345	COG2267	carboxylic ester hydrolase activity
BSY15_RS19350	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BSY15_RS19355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BSY15_RS19360	COG0308	aminopeptidase N
BSY15_RS19365	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BSY15_RS19395	COG0789	Transcriptional regulator
BSY15_RS19400	COG0776	regulation of translation
BSY15_RS19405	COG0072	phenylalanine-tRNA ligase activity
BSY15_RS19405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BSY15_RS19410	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BSY15_RS19415	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BSY15_RS19420	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BSY15_RS19425	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BSY15_RS19430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BSY15_RS19450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BSY15_RS19460	COG4774	siderophore transport
BSY15_RS19465	COG3128	pkhd-type hydroxylase
BSY15_RS19500	COG3193	protein, possibly involved in utilization of glycolate and propanediol
BSY15_RS19515	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BSY15_RS19530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY15_RS19530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BSY15_RS19530	COG0506	proline dehydrogenase activity
BSY15_RS19545	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BSY15_RS19545	COG0519	Catalyzes the synthesis of GMP from XMP
BSY15_RS19565	COG2867	negative regulation of translational initiation
BSY15_RS19570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BSY15_RS19575	COG1024	Enoyl-CoA hydratase
BSY15_RS19585	COG1217	gtp-binding protein TYPA
BSY15_RS19590	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BSY15_RS19595	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BSY15_RS19600	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BSY15_RS19605	COG0195	Participates in both transcription termination and antitermination
BSY15_RS19610	COG0779	Required for maturation of 30S ribosomal subunits
BSY15_RS19615	COG3118	belongs to the thioredoxin family
BSY15_RS19625	COG2863	cytochrome
BSY15_RS19640	COG4172	Belongs to the ABC transporter superfamily
BSY15_RS19645	COG4239	(ABC) transporter, permease
BSY15_RS19650	COG4174	ABC transporter (Permease)
BSY15_RS19655	COG4166	transmembrane transport
BSY15_RS19665	COG1793	dna ligase
BSY15_RS19670	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BSY15_RS19710	COG5377	YqaJ viral recombinase family
BSY15_RS19795	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BSY15_RS19810	COG0583	DNA-binding transcription factor activity
BSY15_RS19825	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BSY15_RS19865	COG4974	Belongs to the 'phage' integrase family
BSY15_RS19930	COG3039	Transposase
BSY15_RS19965	COG2963	transposase activity
BSY15_RS19970	COG0024	Methionine aminopeptidase
BSY15_RS20025	COG0789	Transcriptional regulator
BSY15_RS20035	COG2200	EAL domain
BSY15_RS20080	COG2132	Multicopper oxidase
BSY15_RS20085	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
BSY15_RS20105	COG3191	aminopeptidase activity
BSY15_RS20120	COG0488	(ABC) transporter
BSY15_RS20125	COG0513	Belongs to the DEAD box helicase family
BSY15_RS20130	COG0702	epimerase
BSY15_RS20140	COG4651	solute:proton antiporter activity
BSY15_RS20140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BSY15_RS20155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BSY15_RS20165	COG0776	regulation of translation
BSY15_RS20170	COG0473	3-isopropylmalate dehydrogenase activity
BSY15_RS20180	COG0322	excinuclease ABC activity
BSY15_RS20195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BSY15_RS20200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BSY15_RS20215	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BSY15_RS20220	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BSY15_RS20225	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BSY15_RS20235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BSY15_RS20245	COG1028	Short-chain dehydrogenase reductase Sdr
BSY15_RS20265	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSY15_RS20270	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BSY15_RS20270	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BSY15_RS20275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BSY15_RS20295	COG0560	Phosphoserine phosphatase
BSY15_RS20310	COG2010	Cytochrome c
BSY15_RS20310	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BSY15_RS20320	COG1959	2 iron, 2 sulfur cluster binding
BSY15_RS20335	COG0583	DNA-binding transcription factor activity
BSY15_RS20340	COG0456	acetyltransferase
BSY15_RS20350	COG3530	Putative quorum-sensing-regulated virulence factor
BSY15_RS20355	COG0023	Translation Initiation Factor
BSY15_RS20365	COG0513	Belongs to the DEAD box helicase family
BSY15_RS20375	COG5002	protein histidine kinase activity
BSY15_RS20375	COG5001	Diguanylate cyclase
BSY15_RS20375	COG3447	MASE1 domain protein
BSY15_RS20380	COG0840	transmembrane signaling receptor activity
BSY15_RS20385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BSY15_RS20395	COG1902	pentaerythritol trinitrate reductase activity
BSY15_RS20395	COG0446	pyridine nucleotide-disulphide oxidoreductase
BSY15_RS20405	COG2900	Belongs to the SlyX family
BSY15_RS20410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BSY15_RS20420	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate