locus-tag	class	description
CCX87_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCX87_RS00065	COG1199	ATP-dependent helicase activity
CCX87_RS00070	COG2824	Alkylphosphonate utilization operon protein PhnA
CCX87_RS00080	COG0791	NLP P60 protein
CCX87_RS00085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCX87_RS00105	COG2974	May be involved in recombination
CCX87_RS00110	COG0789	Transcriptional regulator
CCX87_RS00115	COG2608	mercury ion transmembrane transporter activity
CCX87_RS00125	COG0840	transmembrane signaling receptor activity
CCX87_RS00130	COG1902	pentaerythritol trinitrate reductase activity
CCX87_RS00135	COG0625	glutathione transferase activity
CCX87_RS00150	COG0445	tRNA wobble uridine modification
CCX87_RS00155	COG0357	Ribosomal RNA small subunit methyltransferase G
CCX87_RS00160	COG1192	Involved in chromosome partitioning
CCX87_RS00170	COG1475	DNA binding
CCX87_RS00180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCX87_RS00200	COG3639	organic phosphonate transmembrane transporter activity
CCX87_RS00205	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CCX87_RS00215	COG1742	UPF0060 membrane protein
CCX87_RS00220	COG0277	FAD linked oxidase domain protein
CCX87_RS00230	COG2096	Adenosyltransferase
CCX87_RS00235	COG2050	protein possibly involved in aromatic compounds catabolism
CCX87_RS00245	COG2233	PERMEase
CCX87_RS00250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCX87_RS00255	COG1183	phosphatidylcholine synthase activity
CCX87_RS00265	COG0840	transmembrane signaling receptor activity
CCX87_RS00275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX87_RS00280	COG0850	regulation of cytokinetic process
CCX87_RS00290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
CCX87_RS00295	COG2258	MOSC domain
CCX87_RS00300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CCX87_RS00305	COG2267	carboxylic ester hydrolase activity
CCX87_RS00310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCX87_RS00345	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
CCX87_RS00350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CCX87_RS00355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCX87_RS00375	COG2814	Major facilitator Superfamily
CCX87_RS00390	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCX87_RS00395	COG0596	Alpha beta hydrolase
CCX87_RS00400	COG1228	amidohydrolase
CCX87_RS00425	COG0037	tRNA processing
CCX87_RS00430	COG0826	peptidase U32
CCX87_RS00440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS00445	COG0583	DNA-binding transcription factor activity
CCX87_RS00455	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS00475	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS00485	COG0183	Belongs to the thiolase family
CCX87_RS00490	COG0427	acetyl-CoA hydrolase
CCX87_RS00495	COG1024	Enoyl-CoA hydratase
CCX87_RS00500	COG2030	dehydratase
CCX87_RS00505	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS00510	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CCX87_RS00515	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS00540	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS00555	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS00560	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS00565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCX87_RS00570	COG2326	polyphosphate kinase activity
CCX87_RS00575	COG0583	DNA-binding transcription factor activity
CCX87_RS00590	COG2205	protein histidine kinase activity
CCX87_RS00590	COG2198	Histidine kinase
CCX87_RS00590	COG0784	Response regulator, receiver
CCX87_RS00630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CCX87_RS00635	COG0646	methionine synthase
CCX87_RS00635	COG1410	methionine synthase
CCX87_RS00640	COG0604	alcohol dehydrogenase
CCX87_RS00645	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
CCX87_RS00650	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CCX87_RS00670	COG1129	ABC transporter
CCX87_RS00675	COG0606	chelatase, subunit chli
CCX87_RS00685	COG0347	Belongs to the P(II) protein family
CCX87_RS00690	COG0004	ammonium transporteR
CCX87_RS00695	COG0277	FAD linked oxidase domain protein
CCX87_RS00705	COG0247	lactate metabolic process
CCX87_RS00720	COG0386	Belongs to the glutathione peroxidase family
CCX87_RS00735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX87_RS00750	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
CCX87_RS00755	COG0747	negative chemotaxis
CCX87_RS00760	COG0625	glutathione transferase activity
CCX87_RS00795	COG3307	-O-antigen
CCX87_RS00805	COG2070	2-Nitropropane dioxygenase
CCX87_RS00815	COG0745	RESPONSE REGULATOR receiver
CCX87_RS00820	COG2211	Major facilitator Superfamily
CCX87_RS00825	COG0501	Belongs to the peptidase M48B family
CCX87_RS00835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCX87_RS00840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCX87_RS00845	COG0708	Exodeoxyribonuclease III
CCX87_RS00850	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CCX87_RS00860	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX87_RS00865	COG0154	amidase activity
CCX87_RS00870	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CCX87_RS00875	COG1077	Cell shape determining protein MreB Mrl
CCX87_RS00880	COG1792	Involved in formation and maintenance of cell shape
CCX87_RS00890	COG0768	penicillin binding
CCX87_RS00905	COG0765	amino acid transport
CCX87_RS00910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX87_RS00920	COG4584	PFAM Integrase catalytic
CCX87_RS00925	COG1484	DNA-dependent DNA replication
CCX87_RS00930	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCX87_RS00940	COG0702	epimerase
CCX87_RS00950	COG0004	ammonium transporteR
CCX87_RS00965	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCX87_RS00970	COG1127	ABC transporter
CCX87_RS00985	COG3237	CsbD-like
CCX87_RS01010	COG1272	protein, Hemolysin III
CCX87_RS01015	COG2095	MarC family integral membrane protein
CCX87_RS01020	COG0412	Dienelactone hydrolase
CCX87_RS01025	COG0598	Magnesium transport protein CorA
CCX87_RS01035	COG1981	membrane
CCX87_RS01050	COG2945	thiolester hydrolase activity
CCX87_RS01055	COG1686	Belongs to the peptidase S11 family
CCX87_RS01060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CCX87_RS01065	COG0049	tRNA binding
CCX87_RS01070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CCX87_RS01075	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCX87_RS01080	COG0051	transcription antitermination factor activity, RNA binding
CCX87_RS01085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CCX87_RS01090	COG0088	Forms part of the polypeptide exit tunnel
CCX87_RS01095	COG0089	rRNA binding
CCX87_RS01100	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CCX87_RS01105	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CCX87_RS01110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CCX87_RS01115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CCX87_RS01120	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CCX87_RS01125	COG0255	Belongs to the universal ribosomal protein uL29 family
CCX87_RS01130	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CCX87_RS01135	COG0678	peroxiredoxin activity
CCX87_RS01140	COG0456	acetyltransferase
CCX87_RS01145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCX87_RS01160	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CCX87_RS01165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCX87_RS01175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CCX87_RS01180	COG0321	lipoyl(octanoyl) transferase activity
CCX87_RS01185	COG2921	Belongs to the UPF0250 family
CCX87_RS01195	COG0356	it plays a direct role in the translocation of protons across the membrane
CCX87_RS01205	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CCX87_RS01210	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CCX87_RS01215	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CCX87_RS01220	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CCX87_RS01225	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CCX87_RS01230	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CCX87_RS01235	COG4584	PFAM Integrase catalytic
CCX87_RS01240	COG1484	DNA-dependent DNA replication
CCX87_RS01380	COG0277	FAD linked oxidase domain protein
CCX87_RS01400	COG0583	DNA-binding transcription factor activity
CCX87_RS01410	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCX87_RS01415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCX87_RS01425	COG1335	isochorismatase
CCX87_RS01460	COG0583	DNA-binding transcription factor activity
CCX87_RS01475	COG2159	amidohydrolase
CCX87_RS01505	COG0667	Aldo Keto reductase
CCX87_RS01520	COG1414	Transcriptional regulator
CCX87_RS01525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCX87_RS01540	COG4584	PFAM Integrase catalytic
CCX87_RS01545	COG1484	DNA-dependent DNA replication
CCX87_RS01550	COG1012	belongs to the aldehyde dehydrogenase family
CCX87_RS01555	COG3384	dioxygenase
CCX87_RS01575	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CCX87_RS01585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CCX87_RS01605	COG1484	DNA-dependent DNA replication
CCX87_RS01610	COG4584	PFAM Integrase catalytic
CCX87_RS01620	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CCX87_RS01660	COG4948	Mandelate Racemase Muconate Lactonizing
CCX87_RS01670	COG0589	response to stress
CCX87_RS01685	COG2828	Protein conserved in bacteria
CCX87_RS01690	COG0583	DNA-binding transcription factor activity
CCX87_RS01695	COG0730	response to heat
CCX87_RS01705	COG0583	DNA-binding transcription factor activity
CCX87_RS01710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCX87_RS01720	COG2197	response regulator
CCX87_RS01765	COG1484	DNA-dependent DNA replication
CCX87_RS01770	COG4584	PFAM Integrase catalytic
CCX87_RS01780	COG3039	Transposase
CCX87_RS01800	COG4453	Protein conserved in bacteria
CCX87_RS01835	COG3385	transposase activity
CCX87_RS01860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CCX87_RS01870	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CCX87_RS01880	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CCX87_RS01885	COG0081	regulation of translation
CCX87_RS01890	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CCX87_RS01895	COG0222	ribosome binding
CCX87_RS01900	COG0085	RNA polymerase activity
CCX87_RS01905	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CCX87_RS01915	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX87_RS01915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX87_RS01925	COG5000	phosphorelay sensor kinase activity
CCX87_RS01930	COG2204	response regulator
CCX87_RS01940	COG3550	peptidyl-serine autophosphorylation
CCX87_RS01950	COG0443	Heat shock 70 kDa protein
CCX87_RS01955	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CCX87_RS01960	COG0463	Glycosyl transferase, family 2
CCX87_RS01970	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CCX87_RS01975	COG0792	nuclease activity
CCX87_RS01980	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
CCX87_RS01990	COG2084	Dehydrogenase
CCX87_RS02000	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX87_RS02020	COG2733	membrane
CCX87_RS02025	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CCX87_RS02040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CCX87_RS02050	COG0783	Belongs to the Dps family
CCX87_RS02060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCX87_RS02070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CCX87_RS02075	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CCX87_RS02080	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CCX87_RS02085	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CCX87_RS02090	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CCX87_RS02095	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CCX87_RS02100	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CCX87_RS02105	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CCX87_RS02110	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CCX87_RS02115	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CCX87_RS02120	COG1841	ribosomal large subunit assembly
CCX87_RS02125	COG0200	Binds to the 23S rRNA
CCX87_RS02130	COG0201	protein transport
CCX87_RS02135	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CCX87_RS02140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CCX87_RS02145	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CCX87_RS02150	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CCX87_RS02155	COG0202	RNA polymerase activity
CCX87_RS02160	COG0203	ribosomal protein L17
CCX87_RS02190	COG0583	DNA-binding transcription factor activity
CCX87_RS02200	COG2095	MarC family integral membrane protein
CCX87_RS02220	COG0625	glutathione transferase activity
CCX87_RS02240	COG2847	Copper chaperone PCu(A)C
CCX87_RS02285	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS02285	COG0204	Acyl-transferase
CCX87_RS02315	COG0343	queuine tRNA-ribosyltransferase activity
CCX87_RS02340	COG0210	DNA helicase
CCX87_RS02345	COG0679	Auxin Efflux Carrier
CCX87_RS02355	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CCX87_RS02360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CCX87_RS02365	COG2814	Major facilitator Superfamily
CCX87_RS02370	COG0583	DNA-binding transcription factor activity
CCX87_RS02375	COG0861	Integral membrane protein TerC family
CCX87_RS02385	COG2873	o-acetylhomoserine
CCX87_RS02400	COG4584	PFAM Integrase catalytic
CCX87_RS02405	COG1484	DNA-dependent DNA replication
CCX87_RS02505	COG4372	Transposase
CCX87_RS02575	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS02585	COG2124	cytochrome p450
CCX87_RS02595	COG1213	nucleotidyl transferase
CCX87_RS02605	COG0456	acetyltransferase
CCX87_RS02660	COG1132	(ABC) transporter
CCX87_RS02675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCX87_RS02680	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CCX87_RS02700	COG1484	DNA-dependent DNA replication
CCX87_RS02705	COG4584	PFAM Integrase catalytic
CCX87_RS02715	COG1832	CoA-binding protein
CCX87_RS02745	COG0714	Associated with various cellular activities
CCX87_RS02750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX87_RS02755	COG0084	hydrolase, TatD family'
CCX87_RS02770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CCX87_RS02795	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS02800	COG0697	spore germination
CCX87_RS02845	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX87_RS02885	COG0697	spore germination
CCX87_RS02895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX87_RS02905	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CCX87_RS02910	COG1256	bacterial-type flagellum assembly
CCX87_RS02920	COG1706	bacterial-type flagellum-dependent cell motility
CCX87_RS02930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
CCX87_RS02940	COG4787	bacterial-type flagellum-dependent cell motility
CCX87_RS02945	COG1749	Flagellar hook protein flgE
CCX87_RS02950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
CCX87_RS02955	COG1558	bacterial-type flagellum-dependent cell motility
CCX87_RS02960	COG1815	bacterial-type flagellum-dependent cell motility
CCX87_RS02965	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
CCX87_RS02995	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CCX87_RS03005	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
CCX87_RS03010	COG0745	RESPONSE REGULATOR receiver
CCX87_RS03030	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CCX87_RS03045	COG1677	Flagellar hook-basal body complex protein FliE
CCX87_RS03080	COG1580	Controls the rotational direction of flagella during chemotaxis
CCX87_RS03090	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CCX87_RS03100	COG1338	Plays a role in the flagellum-specific transport system
CCX87_RS03105	COG1987	bacterial-type flagellum assembly
CCX87_RS03115	COG2197	response regulator
CCX87_RS03120	COG4585	Histidine kinase
CCX87_RS03125	COG4584	PFAM Integrase catalytic
CCX87_RS03130	COG1484	DNA-dependent DNA replication
CCX87_RS03145	COG2201	protein-glutamate methylesterase activity
CCX87_RS03150	COG2198	Histidine kinase
CCX87_RS03150	COG0643	Histidine kinase
CCX87_RS03155	COG0835	chemotaxis
CCX87_RS03160	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
CCX87_RS03165	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
CCX87_RS03170	COG2201	protein-glutamate methylesterase activity
CCX87_RS03175	COG0488	(ABC) transporter
CCX87_RS03210	COG0789	Transcriptional regulator
CCX87_RS03215	COG1484	DNA-dependent DNA replication
CCX87_RS03220	COG4584	PFAM Integrase catalytic
CCX87_RS03230	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS03235	COG0288	reversible hydration of carbon dioxide
CCX87_RS03240	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
CCX87_RS03245	COG0183	Belongs to the thiolase family
CCX87_RS03265	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS03275	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCX87_RS03290	COG2323	membrane
CCX87_RS03295	COG3012	SEC-C Motif Domain Protein
CCX87_RS03300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CCX87_RS03310	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS03320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCX87_RS03325	COG1024	Enoyl-CoA hydratase
CCX87_RS03340	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX87_RS03380	COG3162	membrane
CCX87_RS03385	COG0477	Major facilitator Superfamily
CCX87_RS03405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CCX87_RS03435	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CCX87_RS03440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CCX87_RS03450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CCX87_RS03455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCX87_RS03460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CCX87_RS03465	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CCX87_RS03470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CCX87_RS03475	COG0316	Belongs to the HesB IscA family
CCX87_RS03480	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CCX87_RS03485	COG0739	heme binding
CCX87_RS03490	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CCX87_RS03495	COG0583	DNA-binding transcription factor activity
CCX87_RS03515	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCX87_RS03520	COG2205	protein histidine kinase activity
CCX87_RS03525	COG3706	GGDEF domain
CCX87_RS03540	COG1522	sequence-specific DNA binding
CCX87_RS03550	COG1056	cytidyltransferase-related domain
CCX87_RS03550	COG1051	belongs to the nudix hydrolase family
CCX87_RS03555	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CCX87_RS03565	COG1560	Kdo2-lipid A biosynthetic process
CCX87_RS03575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
CCX87_RS03585	COG1333	cytochrome c biogenesis protein
CCX87_RS03590	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCX87_RS03595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CCX87_RS03600	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
CCX87_RS03615	COG1965	Belongs to the frataxin family
CCX87_RS03655	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CCX87_RS03660	COG0232	Belongs to the dGTPase family. Type 2 subfamily
CCX87_RS03680	COG0067	glutamate synthase
CCX87_RS03680	COG0070	glutamate synthase
CCX87_RS03680	COG0069	glutamate synthase activity
CCX87_RS03695	COG0765	amino acid transport
CCX87_RS03700	COG1126	abc transporter atp-binding protein
CCX87_RS03705	COG1127	ABC transporter
CCX87_RS03710	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CCX87_RS03715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCX87_RS03735	COG1131	(ABC) transporter
CCX87_RS03740	COG0842	Transport permease protein
CCX87_RS03745	COG5007	Belongs to the BolA IbaG family
CCX87_RS03750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CCX87_RS03755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CCX87_RS03765	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCX87_RS03770	COG0131	Imidazoleglycerol-phosphate dehydratase
CCX87_RS03780	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CCX87_RS03790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CCX87_RS03795	COG0107	imidazoleglycerol-phosphate synthase activity
CCX87_RS03800	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CCX87_RS03805	COG0140	phosphoribosyl-ATP diphosphatase activity
CCX87_RS03825	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCX87_RS03830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CCX87_RS03835	COG0805	protein transport
CCX87_RS03840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX87_RS03845	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CCX87_RS03850	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CCX87_RS03855	COG1970	mechanosensitive ion channel activity
CCX87_RS03860	COG0723	plastoquinol--plastocyanin reductase activity
CCX87_RS03865	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
CCX87_RS03870	COG2857	Cytochrome c1
CCX87_RS03875	COG0625	glutathione transferase activity
CCX87_RS03880	COG2969	positive regulation of protein catabolic process
CCX87_RS03895	COG0653	protein targeting
CCX87_RS03900	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CCX87_RS03910	COG0494	nUDIX hydrolase
CCX87_RS03915	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CCX87_RS03920	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
CCX87_RS03925	COG0237	dephospho-CoA kinase activity
CCX87_RS03930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
CCX87_RS03950	COG0142	geranyltranstransferase activity
CCX87_RS03955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
CCX87_RS03960	COG0211	Belongs to the bacterial ribosomal protein bL27 family
CCX87_RS03965	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CCX87_RS03970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CCX87_RS03975	COG0494	nUDIX hydrolase
CCX87_RS03980	COG0442	prolyl-tRNA aminoacylation
CCX87_RS03985	COG0741	lytic transglycosylase activity
CCX87_RS03990	COG1253	flavin adenine dinucleotide binding
CCX87_RS03995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCX87_RS04000	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CCX87_RS04005	COG2890	protein-(glutamine-N5) methyltransferase activity
CCX87_RS04010	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CCX87_RS04015	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CCX87_RS04025	COG0584	glycerophosphoryl diester phosphodiesterase
CCX87_RS04030	COG3842	ATPase activity
CCX87_RS04035	COG0395	ABC-type sugar transport system, permease component
CCX87_RS04040	COG1175	transmembrane transport
CCX87_RS04045	COG1653	transport
CCX87_RS04050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX87_RS04090	COG2226	methyltransferase
CCX87_RS04105	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCX87_RS04125	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CCX87_RS04140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCX87_RS04145	COG0302	gtp cyclohydrolase
CCX87_RS04160	COG1280	lysine exporter protein (LysE YggA)
CCX87_RS04170	COG0154	amidase activity
CCX87_RS04180	COG4608	Belongs to the ABC transporter superfamily
CCX87_RS04185	COG0444	Belongs to the ABC transporter superfamily
CCX87_RS04190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX87_RS04200	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CCX87_RS04205	COG0193	aminoacyl-tRNA hydrolase activity
CCX87_RS04210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CCX87_RS04215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CCX87_RS04225	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CCX87_RS04240	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
CCX87_RS04250	COG1194	a g-specific adenine glycosylase
CCX87_RS04255	COG1660	Displays ATPase and GTPase activities
CCX87_RS04260	COG0497	DNA recombination
CCX87_RS04265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CCX87_RS04270	COG1420	regulation of RNA biosynthetic process
CCX87_RS04310	COG0582	viral genome integration into host DNA
CCX87_RS04325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCX87_RS04330	COG1758	RNA polymerase activity
CCX87_RS04335	COG0194	GDP metabolic process
CCX87_RS04340	COG1561	YicC-like family, N-terminal region
CCX87_RS04360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CCX87_RS04365	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CCX87_RS04380	COG0640	Transcriptional regulator
CCX87_RS04385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCX87_RS04400	COG0798	PFAM Bile acid sodium symporter
CCX87_RS04475	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CCX87_RS04490	COG1484	DNA-dependent DNA replication
CCX87_RS04495	COG4584	PFAM Integrase catalytic
CCX87_RS04500	COG1475	DNA binding
CCX87_RS04515	COG1395	domain, Protein
CCX87_RS04545	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCX87_RS04575	COG1193	negative regulation of DNA recombination
CCX87_RS04580	COG2003	Belongs to the UPF0758 family
CCX87_RS04585	COG1047	Peptidyl-prolyl cis-trans
CCX87_RS04590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CCX87_RS04595	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
CCX87_RS04595	COG0617	tRNA 3'-terminal CCA addition
CCX87_RS04595	COG0517	IMP dehydrogenase activity
CCX87_RS04600	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CCX87_RS04615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CCX87_RS04615	COG0574	Belongs to the PEP-utilizing enzyme family
CCX87_RS04635	COG0180	Tryptophanyl-tRNA synthetase
CCX87_RS04640	COG1994	Peptidase M50
CCX87_RS04645	COG0009	L-threonylcarbamoyladenylate synthase
CCX87_RS04650	COG0613	PHP domain protein
CCX87_RS04665	COG4591	ABC-type transport system involved in lipoprotein release permease component
CCX87_RS04670	COG1136	(ABC) transporter
CCX87_RS04675	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CCX87_RS04680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CCX87_RS04685	COG0196	riboflavin kinase activity
CCX87_RS04695	COG3781	membrane
CCX87_RS04700	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS04705	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS04710	COG3132	Protein of unknown function, DUF480
CCX87_RS04715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CCX87_RS04725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX87_RS04725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CCX87_RS04735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CCX87_RS04740	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CCX87_RS04745	COG0492	ferredoxin-NADP+ reductase activity
CCX87_RS04750	COG1674	ftsk spoiiie
CCX87_RS04755	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CCX87_RS04760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCX87_RS04765	COG0559	Belongs to the binding-protein-dependent transport system permease family
CCX87_RS04790	COG1392	Phosphate transport regulator
CCX87_RS04795	COG0306	phosphate transporter
CCX87_RS04810	COG0228	four-way junction DNA binding
CCX87_RS04815	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CCX87_RS04820	COG0336	Belongs to the RNA methyltransferase TrmD family
CCX87_RS04825	COG0335	large ribosomal subunit rRNA binding
CCX87_RS04835	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CCX87_RS04840	COG1162	GTPase activity
CCX87_RS04845	COG2154	pterin-4-alpha-carbinolamine dehydratase
CCX87_RS04850	COG0501	Belongs to the peptidase M48B family
CCX87_RS04855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CCX87_RS04860	COG0513	Belongs to the DEAD box helicase family
CCX87_RS04870	COG2814	Major facilitator Superfamily
CCX87_RS04875	COG0582	viral genome integration into host DNA
CCX87_RS04890	COG0582	viral genome integration into host DNA
CCX87_RS04945	COG2084	Dehydrogenase
CCX87_RS04950	COG0516	GMP reductase activity
CCX87_RS04960	COG0210	DNA helicase
CCX87_RS04970	COG4584	PFAM Integrase catalytic
CCX87_RS04975	COG1484	DNA-dependent DNA replication
CCX87_RS05000	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCX87_RS05030	COG0625	glutathione transferase activity
CCX87_RS05035	COG0625	glutathione transferase activity
CCX87_RS05040	COG0655	NAD(P)H dehydrogenase (quinone) activity
CCX87_RS05045	COG0412	Dienelactone hydrolase
CCX87_RS05060	COG3275	phosphorelay sensor kinase activity
CCX87_RS05065	COG0165	Argininosuccinate lyase
CCX87_RS05070	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS05075	COG5001	Diguanylate cyclase
CCX87_RS05075	COG3447	MASE1 domain protein
CCX87_RS05075	COG5002	protein histidine kinase activity
CCX87_RS05080	COG1304	FMN binding
CCX87_RS05085	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CCX87_RS05090	COG0840	transmembrane signaling receptor activity
CCX87_RS05095	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCX87_RS05095	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CCX87_RS05105	COG3022	response to hydroperoxide
CCX87_RS05110	COG1530	ribonuclease E activity
CCX87_RS05130	COG0616	signal peptide processing
CCX87_RS05130	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCX87_RS05135	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CCX87_RS05140	COG0424	maF-like protein
CCX87_RS05145	COG1399	metal-binding, possibly nucleic acid-binding protein
CCX87_RS05150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
CCX87_RS05155	COG0416	fatty acid biosynthetic process
CCX87_RS05160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CCX87_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS05175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CCX87_RS05180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CCX87_RS05195	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
CCX87_RS05200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX87_RS05205	COG0481	GTPase activity
CCX87_RS05210	COG0681	Belongs to the peptidase S26 family
CCX87_RS05220	COG0571	ribonuclease III activity
CCX87_RS05225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CCX87_RS05230	COG1381	Involved in DNA repair and RecF pathway recombination
CCX87_RS05235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CCX87_RS05240	COG0736	holo-[acyl-carrier-protein] synthase activity
CCX87_RS05245	COG1472	Belongs to the glycosyl hydrolase 3 family
CCX87_RS05250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CCX87_RS05255	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCX87_RS05260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CCX87_RS05275	COG0438	transferase activity, transferring glycosyl groups
CCX87_RS05300	COG0762	integral membrane protein
CCX87_RS05305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CCX87_RS05310	COG0159	tryptophan synthase activity
CCX87_RS05315	COG0133	tryptophan synthase activity
CCX87_RS05320	COG0135	phosphoribosylanthranilate isomerase activity
CCX87_RS05325	COG0101	tRNA pseudouridine synthase activity
CCX87_RS05335	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CCX87_RS05340	COG0473	3-isopropylmalate dehydrogenase activity
CCX87_RS05345	COG0066	3-isopropylmalate dehydratase activity
CCX87_RS05355	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CCX87_RS05365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCX87_RS05370	COG0484	heat shock protein binding
CCX87_RS05375	COG0443	Heat shock 70 kDa protein
CCX87_RS05380	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CCX87_RS05385	COG0360	Binds together with S18 to 16S ribosomal RNA
CCX87_RS05395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CCX87_RS05400	COG0359	binds to the 23S rRNA
CCX87_RS05415	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
CCX87_RS05420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CCX87_RS05430	COG0436	Aminotransferase
CCX87_RS05440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CCX87_RS05445	COG1763	Mo-molybdopterin cofactor biosynthetic process
CCX87_RS05475	COG0314	molybdopterin synthase activity
CCX87_RS05480	COG0542	response to heat
CCX87_RS05495	COG0784	Response regulator, receiver
CCX87_RS05495	COG2205	protein histidine kinase activity
CCX87_RS05500	COG2197	response regulator
CCX87_RS05525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCX87_RS05530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CCX87_RS05535	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
CCX87_RS05555	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCX87_RS05555	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CCX87_RS05560	COG4636	protein conserved in cyanobacteria
CCX87_RS05570	COG4969	Belongs to the N-Me-Phe pilin family
CCX87_RS05590	COG0436	Aminotransferase
CCX87_RS05595	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CCX87_RS05600	COG1185	polyribonucleotide nucleotidyltransferase activity
CCX87_RS05605	COG3321	synthase
CCX87_RS05605	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS05605	COG0604	alcohol dehydrogenase
CCX87_RS05610	COG0149	triose-phosphate isomerase activity
CCX87_RS05625	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCX87_RS05630	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCX87_RS05635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCX87_RS05640	COG0649	NAD binding
CCX87_RS05655	COG1034	ATP synthesis coupled electron transport
CCX87_RS05660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
CCX87_RS05665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CCX87_RS05675	COG0713	ATP synthesis coupled electron transport
CCX87_RS05690	COG1007	ATP synthesis coupled electron transport
CCX87_RS05705	COG1132	(ABC) transporter
CCX87_RS05710	COG4584	PFAM Integrase catalytic
CCX87_RS05755	COG0071	Belongs to the small heat shock protein (HSP20) family
CCX87_RS05760	COG4181	ATPase activity
CCX87_RS05765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CCX87_RS05770	COG2814	Major facilitator Superfamily
CCX87_RS05780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CCX87_RS05790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CCX87_RS05795	COG0586	Pfam SNARE associated Golgi protein
CCX87_RS05810	COG0860	N-Acetylmuramoyl-L-alanine amidase
CCX87_RS05815	COG0802	atpase or kinase
CCX87_RS05820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CCX87_RS05830	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS05835	COG4974	Belongs to the 'phage' integrase family
CCX87_RS05840	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CCX87_RS05845	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
CCX87_RS05850	COG2833	Protein of unknown function (DUF455)
CCX87_RS05860	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CCX87_RS05870	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CCX87_RS05875	COG0148	phosphopyruvate hydratase activity
CCX87_RS05880	COG2877	3-deoxy-8-phosphooctulonate synthase activity
CCX87_RS05885	COG0504	CTP synthase activity
CCX87_RS05890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCX87_RS05895	COG0756	dUTP diphosphatase activity
CCX87_RS05905	COG1047	Peptidyl-prolyl cis-trans
CCX87_RS05910	COG2850	peptidyl-arginine hydroxylation
CCX87_RS05930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
CCX87_RS05935	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CCX87_RS05940	COG0500	methyltransferase
CCX87_RS05955	COG0741	lytic transglycosylase activity
CCX87_RS05965	COG0840	transmembrane signaling receptor activity
CCX87_RS05980	COG2308	Evidence 4 Homologs of previously reported genes of
CCX87_RS05990	COG4628	conserved protein (DUF2132)
CCX87_RS06010	COG3634	alkyl hydroperoxide reductase activity
CCX87_RS06020	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
CCX87_RS06035	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CCX87_RS06060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCX87_RS06065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS06080	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS06090	COG0156	8-amino-7-oxononanoate synthase activity
CCX87_RS06095	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CCX87_RS06100	COG0405	Gamma-glutamyltransferase
CCX87_RS06105	COG3540	Alkaline phosphatase
CCX87_RS06115	COG0604	alcohol dehydrogenase
CCX87_RS06115	COG3321	synthase
CCX87_RS06115	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS06120	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CCX87_RS06125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCX87_RS06140	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CCX87_RS06145	COG1187	pseudouridine synthase activity
CCX87_RS06150	COG0105	UTP biosynthetic process
CCX87_RS06155	COG0820	rRNA (adenine-C2-)-methyltransferase activity
CCX87_RS06170	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CCX87_RS06175	COG0124	histidyl-tRNA synthetase
CCX87_RS06185	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCX87_RS06190	COG1160	GTP binding
CCX87_RS06195	COG1923	regulation of RNA biosynthetic process
CCX87_RS06200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CCX87_RS06205	COG0330	HflC and HflK could
CCX87_RS06210	COG0330	HflC and HflK could
CCX87_RS06215	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
CCX87_RS06220	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CCX87_RS06225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CCX87_RS06230	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CCX87_RS06235	COG1484	DNA-dependent DNA replication
CCX87_RS06240	COG4584	PFAM Integrase catalytic
CCX87_RS06300	COG0174	glutamine synthetase
CCX87_RS06310	COG3852	Histidine kinase
CCX87_RS06315	COG2204	response regulator
CCX87_RS06320	COG0708	Exodeoxyribonuclease III
CCX87_RS06330	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CCX87_RS06335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCX87_RS06340	COG0277	FAD linked oxidase domain protein
CCX87_RS06350	COG1295	ribonuclease BN
CCX87_RS06355	COG0277	FAD linked oxidase domain protein
CCX87_RS06370	COG0517	IMP dehydrogenase activity
CCX87_RS06380	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CCX87_RS06390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CCX87_RS06395	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CCX87_RS06400	COG0741	lytic transglycosylase activity
CCX87_RS06420	COG0557	exoribonuclease II activity
CCX87_RS06425	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CCX87_RS06425	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CCX87_RS06440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCX87_RS06450	COG0052	Belongs to the universal ribosomal protein uS2 family
CCX87_RS06455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CCX87_RS06460	COG0528	UMP kinase activity
CCX87_RS06465	COG0233	cytoplasmic translational termination
CCX87_RS06470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCX87_RS06480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
CCX87_RS06485	COG0750	zinc metalloprotease
CCX87_RS06500	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCX87_RS06505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
CCX87_RS06510	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCX87_RS06515	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCX87_RS06520	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CCX87_RS06525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX87_RS06530	COG0505	Belongs to the CarA family
CCX87_RS06535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
CCX87_RS06540	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCX87_RS06560	COG1534	Rna-binding protein
CCX87_RS06565	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
CCX87_RS06570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CCX87_RS06585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CCX87_RS06630	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
CCX87_RS06635	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCX87_RS06640	COG0573	inorganic phosphate transmembrane transporter activity
CCX87_RS06645	COG0581	inorganic phosphate transmembrane transporter activity
CCX87_RS06650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CCX87_RS06655	COG0704	Plays a role in the regulation of phosphate uptake
CCX87_RS06660	COG0745	RESPONSE REGULATOR receiver
CCX87_RS06670	COG0534	Mate efflux family protein
CCX87_RS06680	COG0254	rRNA binding
CCX87_RS06685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CCX87_RS06705	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
CCX87_RS06715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CCX87_RS06720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CCX87_RS06725	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CCX87_RS06740	COG0741	lytic transglycosylase activity
CCX87_RS06740	COG1388	LysM domain
CCX87_RS06745	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCX87_RS06750	COG2226	methyltransferase
CCX87_RS06755	COG0328	RNA-DNA hybrid ribonuclease activity
CCX87_RS06785	COG0746	molybdenum cofactor guanylyltransferase activity
CCX87_RS06790	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CCX87_RS06805	COG0701	Predicted permease
CCX87_RS06840	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CCX87_RS06845	COG0840	transmembrane signaling receptor activity
CCX87_RS06855	COG0835	chemotaxis
CCX87_RS06870	COG0347	Belongs to the P(II) protein family
CCX87_RS06880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
CCX87_RS06900	COG1595	DNA-templated transcription, initiation
CCX87_RS06905	COG0028	Belongs to the TPP enzyme family
CCX87_RS06910	COG0440	acetolactate synthase activity
CCX87_RS06915	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CCX87_RS06920	COG1183	phosphatidylcholine synthase activity
CCX87_RS06925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCX87_RS06935	COG1414	Transcriptional regulator
CCX87_RS06940	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
CCX87_RS06945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CCX87_RS06955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS06960	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
CCX87_RS06975	COG4584	PFAM Integrase catalytic
CCX87_RS06980	COG1484	DNA-dependent DNA replication
CCX87_RS06985	COG2358	TRAP transporter, solute receptor (TAXI family
CCX87_RS06990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS07005	COG2986	histidine ammonia-lyase
CCX87_RS07010	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CCX87_RS07025	COG1228	amidohydrolase
CCX87_RS07055	COG2832	Protein of unknown function (DUF454)
CCX87_RS07060	COG0242	peptide deformylase activity
CCX87_RS07070	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
CCX87_RS07075	COG0308	aminopeptidase N
CCX87_RS07085	COG2267	carboxylic ester hydrolase activity
CCX87_RS07090	COG0667	Aldo Keto reductase
CCX87_RS07095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CCX87_RS07100	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
CCX87_RS07110	COG3577	Aspartyl protease
CCX87_RS07115	COG1666	GTP binding
CCX87_RS07120	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CCX87_RS07125	COG0137	argininosuccinate synthase activity
CCX87_RS07130	COG3123	guanosine phosphorylase activity
CCX87_RS07140	COG1393	Belongs to the ArsC family
CCX87_RS07145	COG0285	dihydrofolate synthase activity
CCX87_RS07165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCX87_RS07205	COG1840	ABC-type Fe3 transport system, periplasmic component
CCX87_RS07225	COG2944	sequence-specific DNA binding
CCX87_RS07230	COG0732	type I restriction modification DNA specificity domain
CCX87_RS07235	COG1484	DNA-dependent DNA replication
CCX87_RS07240	COG4584	PFAM Integrase catalytic
CCX87_RS07245	COG0732	type I restriction modification DNA specificity domain
CCX87_RS07255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CCX87_RS07255	COG4651	solute:proton antiporter activity
CCX87_RS07265	COG0513	Belongs to the DEAD box helicase family
CCX87_RS07270	COG0488	(ABC) transporter
CCX87_RS07285	COG3191	aminopeptidase activity
CCX87_RS07305	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
CCX87_RS07310	COG2132	Multicopper oxidase
CCX87_RS07375	COG1793	dna ligase
CCX87_RS07385	COG4166	transmembrane transport
CCX87_RS07390	COG4174	ABC transporter (Permease)
CCX87_RS07415	COG4239	(ABC) transporter, permease
CCX87_RS07420	COG4172	Belongs to the ABC transporter superfamily
CCX87_RS07455	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX87_RS07465	COG0557	exoribonuclease II activity
CCX87_RS07490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCX87_RS07495	COG0779	Required for maturation of 30S ribosomal subunits
CCX87_RS07500	COG0195	Participates in both transcription termination and antitermination
CCX87_RS07505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CCX87_RS07510	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CCX87_RS07515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CCX87_RS07530	COG1024	Enoyl-CoA hydratase
CCX87_RS07550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CCX87_RS07555	COG2867	negative regulation of translational initiation
CCX87_RS07560	COG2914	Belongs to the UPF0125 (RnfH) family
CCX87_RS07575	COG0519	Catalyzes the synthesis of GMP from XMP
CCX87_RS07575	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CCX87_RS07580	COG0582	viral genome integration into host DNA
CCX87_RS07605	COG1192	Involved in chromosome partitioning
CCX87_RS07645	COG2003	Belongs to the UPF0758 family
CCX87_RS07720	COG1201	RNA secondary structure unwinding
CCX87_RS07825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCX87_RS07925	COG4584	PFAM Integrase catalytic
CCX87_RS07930	COG1484	DNA-dependent DNA replication
CCX87_RS07935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCX87_RS07940	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CCX87_RS07945	COG0251	oxidation-reduction process
CCX87_RS07970	COG1177	transmembrane transport
CCX87_RS07980	COG3842	ATPase activity
CCX87_RS07990	COG0583	DNA-binding transcription factor activity
CCX87_RS07995	COG0688	phosphatidylethanolamine metabolic process
CCX87_RS08005	COG0123	including yeast histone deacetylase and acetoin utilization protein
CCX87_RS08015	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CCX87_RS08035	COG1611	Belongs to the LOG family
CCX87_RS08040	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CCX87_RS08075	COG2212	antiporter activity
CCX87_RS08080	COG1863	multisubunit Na H antiporter MnhE subunit
CCX87_RS08085	COG0651	ATP synthesis coupled electron transport
CCX87_RS08090	COG1006	Multisubunit Na H antiporter MnhC subunit
CCX87_RS08095	COG2111	Na H antiporter
CCX87_RS08095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CCX87_RS08105	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
CCX87_RS08115	COG0776	regulation of translation
CCX87_RS08125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCX87_RS08130	COG0287	Prephenate dehydrogenase
CCX87_RS08135	COG1605	Chorismate mutase
CCX87_RS08135	COG0077	Prephenate dehydratase
CCX87_RS08140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CCX87_RS08155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CCX87_RS08190	COG0670	Belongs to the BI1 family
CCX87_RS08195	COG3193	protein, possibly involved in utilization of glycolate and propanediol
CCX87_RS08235	COG3128	pkhd-type hydroxylase
CCX87_RS08240	COG4774	siderophore transport
CCX87_RS08250	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CCX87_RS08265	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CCX87_RS08270	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CCX87_RS08275	COG0291	Belongs to the bacterial ribosomal protein bL35 family
CCX87_RS08280	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CCX87_RS08285	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CCX87_RS08290	COG0072	phenylalanine-tRNA ligase activity
CCX87_RS08290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX87_RS08295	COG0776	regulation of translation
CCX87_RS08300	COG0789	Transcriptional regulator
CCX87_RS08310	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCX87_RS08345	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CCX87_RS08350	COG0024	Methionine aminopeptidase
CCX87_RS08355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CCX87_RS08355	COG0047	phosphoribosylformylglycinamidine synthase activity
CCX87_RS08365	COG2354	Protein conserved in bacteria
CCX87_RS08370	COG3047	cAMP biosynthetic process
CCX87_RS08375	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
CCX87_RS08380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CCX87_RS08395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX87_RS08400	COG0826	peptidase U32
CCX87_RS08425	COG1619	proteins homologs of microcin C7 resistance protein MccF
CCX87_RS08445	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS08460	COG1024	Enoyl-CoA hydratase
CCX87_RS08465	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCX87_RS08480	COG2022	thiamine diphosphate biosynthetic process
CCX87_RS08495	COG0351	phosphomethylpyrimidine kinase
CCX87_RS08500	COG4584	PFAM Integrase catalytic
CCX87_RS08505	COG1484	DNA-dependent DNA replication
CCX87_RS08525	COG0492	ferredoxin-NADP+ reductase activity
CCX87_RS08530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CCX87_RS08535	COG0529	Catalyzes the synthesis of activated sulfate
CCX87_RS08535	COG2895	sulfate adenylyltransferase (ATP) activity
CCX87_RS08540	COG0175	sulfate reduction
CCX87_RS08545	COG0175	sulfate reduction
CCX87_RS08560	COG0730	response to heat
CCX87_RS08565	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CCX87_RS08565	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CCX87_RS08570	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
CCX87_RS08575	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CCX87_RS08580	COG0431	NADPH-dependent FMN reductase
CCX87_RS08585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCX87_RS08590	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCX87_RS08600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS08605	COG1116	anion transmembrane transporter activity
CCX87_RS08615	COG0583	DNA-binding transcription factor activity
CCX87_RS08620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCX87_RS08635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS08650	COG0628	permease
CCX87_RS08655	COG0567	Dehydrogenase, E1 component
CCX87_RS08660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCX87_RS08665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCX87_RS08670	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CCX87_RS08690	COG1199	ATP-dependent helicase activity
CCX87_RS08705	COG2329	Antibiotic biosynthesis monooxygenase
CCX87_RS08715	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CCX87_RS08720	COG0542	response to heat
CCX87_RS08725	COG2951	lytic endotransglycosylase activity
CCX87_RS08730	COG2925	Exonuclease
CCX87_RS08740	COG0700	Nucleoside recognition
CCX87_RS08745	COG0217	transcriptional regulatory protein
CCX87_RS08750	COG0484	heat shock protein binding
CCX87_RS08770	COG3706	GGDEF domain
CCX87_RS08775	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CCX87_RS08790	COG0433	COG0433 Predicted ATPase
CCX87_RS08795	COG0217	transcriptional regulatory protein
CCX87_RS08800	COG0151	Belongs to the GarS family
CCX87_RS08805	COG0408	coproporphyrinogen oxidase activity
CCX87_RS08810	COG0799	negative regulation of ribosome biogenesis
CCX87_RS08815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CCX87_RS08820	COG0424	maF-like protein
CCX87_RS08825	COG1530	ribonuclease E activity
CCX87_RS08860	COG4372	Transposase
CCX87_RS08865	COG1484	DNA-dependent DNA replication
CCX87_RS08870	COG4584	PFAM Integrase catalytic
CCX87_RS08875	COG4372	Transposase
CCX87_RS08880	COG4584	PFAM Integrase catalytic
CCX87_RS08885	COG1484	DNA-dependent DNA replication
CCX87_RS08890	COG3039	Transposase
CCX87_RS08895	COG0436	Aminotransferase
CCX87_RS08900	COG0583	DNA-binding transcription factor activity
CCX87_RS08910	COG0795	lipopolysaccharide-transporting ATPase activity
CCX87_RS08920	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CCX87_RS08940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX87_RS08960	COG4974	Belongs to the 'phage' integrase family
CCX87_RS08965	COG0464	growth
CCX87_RS08980	COG1484	DNA-dependent DNA replication
CCX87_RS08985	COG4584	PFAM Integrase catalytic
CCX87_RS09075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CCX87_RS09080	COG0252	asparaginase activity
CCX87_RS09085	COG0563	adenylate kinase activity
CCX87_RS09090	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
CCX87_RS09095	COG2835	tetraacyldisaccharide 4'-kinase activity
CCX87_RS09100	COG1663	tetraacyldisaccharide 4'-kinase activity
CCX87_RS09105	COG0848	biopolymer transport protein
CCX87_RS09110	COG0811	peptide transport
CCX87_RS09115	COG1570	exodeoxyribonuclease VII activity
CCX87_RS09120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CCX87_RS09155	COG2249	NAD(P)H dehydrogenase (quinone) activity
CCX87_RS09175	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS09215	COG1196	nuclear chromosome segregation
CCX87_RS09225	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CCX87_RS09230	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCX87_RS09275	COG3243	poly(R)-hydroxyalkanoic acid synthase
CCX87_RS09280	COG0183	Belongs to the thiolase family
CCX87_RS09285	COG0840	transmembrane signaling receptor activity
CCX87_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS09300	COG0488	(ABC) transporter
CCX87_RS09305	COG2890	protein-(glutamine-N5) methyltransferase activity
CCX87_RS09310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCX87_RS09320	COG2171	N-acyltransferase activity
CCX87_RS09325	COG0436	Aminotransferase
CCX87_RS09330	COG2878	Part of a membrane complex involved in electron transport
CCX87_RS09365	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCX87_RS09370	COG1596	polysaccharide export
CCX87_RS09375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCX87_RS09380	COG0489	protein tyrosine kinase activity
CCX87_RS09380	COG3206	protein involved in exopolysaccharide biosynthesis
CCX87_RS09385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CCX87_RS09390	COG0662	Cupin 2, conserved barrel domain protein
CCX87_RS09390	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
CCX87_RS09395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CCX87_RS09415	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CCX87_RS09440	COG1216	Glycosyl transferase, family 2
CCX87_RS09450	COG0110	maltose O-acetyltransferase activity
CCX87_RS09455	COG0297	glycogen (starch) synthase activity
CCX87_RS09470	COG0297	glycogen (starch) synthase activity
CCX87_RS09480	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CCX87_RS09485	COG2827	Endonuclease containing a URI domain
CCX87_RS09505	COG1802	Transcriptional regulator
CCX87_RS09510	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCX87_RS09510	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
CCX87_RS09525	COG1703	isobutyryl-CoA mutase activity
CCX87_RS09530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CCX87_RS09535	COG4770	biotin carboxylase activity
CCX87_RS09550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CCX87_RS09565	COG0640	Transcriptional regulator
CCX87_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS09590	COG0534	Mate efflux family protein
CCX87_RS09615	COG0346	lactoylglutathione lyase activity
CCX87_RS09630	COG2032	superoxide dismutase activity
CCX87_RS09635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CCX87_RS09665	COG0259	pyridoxamine-phosphate oxidase activity
CCX87_RS09680	COG2203	Gaf domain
CCX87_RS09680	COG3706	GGDEF domain
CCX87_RS09680	COG4251	negative regulation of phosphorylation
CCX87_RS09680	COG5001	Diguanylate cyclase
CCX87_RS09710	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX87_RS09715	COG1309	transcriptional regulator
CCX87_RS09730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CCX87_RS09745	COG1125	glycine betaine transport
CCX87_RS09745	COG0517	IMP dehydrogenase activity
CCX87_RS09750	COG0045	succinate-CoA ligase (ADP-forming) activity
CCX87_RS09750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CCX87_RS09750	COG1042	CoA-binding domain protein
CCX87_RS09785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCX87_RS09800	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CCX87_RS09805	COG0791	NLP P60 protein
CCX87_RS09830	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
CCX87_RS09835	COG0527	aspartate kinase activity
CCX87_RS09850	COG1484	DNA-dependent DNA replication
CCX87_RS09855	COG4584	PFAM Integrase catalytic
CCX87_RS09865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCX87_RS09870	COG0508	dehydrogenase complex catalyzes the overall conversion of
CCX87_RS09875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
CCX87_RS09885	COG4566	intracellular signal transduction
CCX87_RS09890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CCX87_RS09905	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CCX87_RS09910	COG0167	dihydroorotate dehydrogenase activity
CCX87_RS09945	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CCX87_RS09955	COG0443	Heat shock 70 kDa protein
CCX87_RS09960	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
CCX87_RS09965	COG0316	Belongs to the HesB IscA family
CCX87_RS09970	COG0822	iron-sulfur transferase activity
CCX87_RS09975	COG1104	cysteine desulfurase activity
CCX87_RS09980	COG1959	2 iron, 2 sulfur cluster binding
CCX87_RS09985	COG0556	nucleotide-excision repair
CCX87_RS10005	COG1739	Uncharacterized protein family UPF0029
CCX87_RS10030	COG3550	peptidyl-serine autophosphorylation
CCX87_RS10045	COG2807	transmembrane transport
CCX87_RS10080	COG0179	Fumarylacetoacetate (FAA) hydrolase
CCX87_RS10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CCX87_RS10100	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CCX87_RS10105	COG4181	ATPase activity
CCX87_RS10150	COG1054	Belongs to the UPF0176 family
CCX87_RS10155	COG1741	Belongs to the pirin family
CCX87_RS10170	COG2259	Doxx family
CCX87_RS10175	COG1741	Belongs to the pirin family
CCX87_RS10185	COG1233	COG1233 Phytoene dehydrogenase and related
CCX87_RS10190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCX87_RS10195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CCX87_RS10205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CCX87_RS10210	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CCX87_RS10265	COG0564	pseudouridine synthase activity
CCX87_RS10270	COG2982	Protein involved in outer membrane biogenesis
CCX87_RS10275	COG0587	DNA-directed DNA polymerase activity
CCX87_RS10290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
CCX87_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS10340	COG4120	Belongs to the binding-protein-dependent transport system permease family
CCX87_RS10355	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CCX87_RS10365	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CCX87_RS10365	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CCX87_RS10370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
CCX87_RS10375	COG0509	glycine decarboxylation via glycine cleavage system
CCX87_RS10380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCX87_RS10380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CCX87_RS10425	COG0545	Peptidyl-prolyl cis-trans isomerase
CCX87_RS10435	COG0564	pseudouridine synthase activity
CCX87_RS10440	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS10445	COG0183	Belongs to the thiolase family
CCX87_RS10455	COG0589	response to stress
CCX87_RS10475	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS10480	COG1643	Atp-dependent helicase
CCX87_RS10485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCX87_RS10485	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
CCX87_RS10490	COG1054	Belongs to the UPF0176 family
CCX87_RS10500	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
CCX87_RS10505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CCX87_RS10510	COG4208	sulfate ABC transporter
CCX87_RS10520	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CCX87_RS10530	COG0583	DNA-binding transcription factor activity
CCX87_RS10535	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CCX87_RS10565	COG2011	ABC-type metal ion transport system permease component
CCX87_RS10570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CCX87_RS10610	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CCX87_RS10625	COG0823	Involved in the tonB-independent uptake of proteins
CCX87_RS10630	COG1132	(ABC) transporter
CCX87_RS10640	COG0084	hydrolase, TatD family'
CCX87_RS10650	COG0470	DNA polymerase III
CCX87_RS10655	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CCX87_RS10660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CCX87_RS10670	COG2153	protein acetylation
CCX87_RS10675	COG0657	acetylesterase activity
CCX87_RS10690	COG2183	response to ionizing radiation
CCX87_RS10700	COG2197	response regulator
CCX87_RS10705	COG2814	Major facilitator Superfamily
CCX87_RS10720	COG2153	protein acetylation
CCX87_RS10725	COG2130	NADP-dependent
CCX87_RS10735	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS10750	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS10760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX87_RS10765	COG0183	Belongs to the thiolase family
CCX87_RS10770	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCX87_RS10770	COG1024	Enoyl-CoA hydratase
CCX87_RS10780	COG0411	ABC transporter
CCX87_RS10790	COG0559	Belongs to the binding-protein-dependent transport system permease family
CCX87_RS10800	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS10805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CCX87_RS10810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CCX87_RS10815	COG2917	probably involved in intracellular septation
CCX87_RS10825	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX87_RS10835	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CCX87_RS10850	COG0506	proline dehydrogenase activity
CCX87_RS10850	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCX87_RS10850	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CCX87_RS10865	COG4772	TonB-dependent receptor
CCX87_RS10880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CCX87_RS10885	COG4372	Transposase
CCX87_RS10900	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX87_RS10910	COG0776	regulation of translation
CCX87_RS10915	COG0473	3-isopropylmalate dehydrogenase activity
CCX87_RS10925	COG0322	excinuclease ABC activity
CCX87_RS10935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CCX87_RS10940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS10945	COG0583	DNA-binding transcription factor activity
CCX87_RS10955	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CCX87_RS10960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCX87_RS10965	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
CCX87_RS11095	COG0719	Fe-S assembly protein
CCX87_RS11095	COG1372	Participates in initiation and elongation during chromosome replication
CCX87_RS11130	COG4584	PFAM Integrase catalytic
CCX87_RS11135	COG1484	DNA-dependent DNA replication
CCX87_RS11190	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
CCX87_RS11360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CCX87_RS11370	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS11390	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCX87_RS11395	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
CCX87_RS11395	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
CCX87_RS11400	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CCX87_RS11410	COG0560	Phosphoserine phosphatase
CCX87_RS11415	COG1959	2 iron, 2 sulfur cluster binding
CCX87_RS11420	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
CCX87_RS11435	COG0583	DNA-binding transcription factor activity
CCX87_RS11440	COG3530	Putative quorum-sensing-regulated virulence factor
CCX87_RS11445	COG0023	Translation Initiation Factor
CCX87_RS11460	COG0513	Belongs to the DEAD box helicase family
CCX87_RS11470	COG0667	Aldo Keto reductase
CCX87_RS11475	COG2900	Belongs to the SlyX family
CCX87_RS11480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CCX87_RS11485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CCX87_RS11490	COG0583	DNA-binding transcription factor activity
CCX87_RS11500	COG4829	muconolactone delta-isomerase
CCX87_RS11530	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CCX87_RS11535	COG1492	cobalamin metabolic process
CCX87_RS11540	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CCX87_RS11545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
CCX87_RS11550	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
CCX87_RS11555	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
CCX87_RS11560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CCX87_RS11565	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
CCX87_RS11575	COG4206	TonB-dependent receptor
CCX87_RS11590	COG0730	response to heat
CCX87_RS11615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX87_RS11650	COG3278	Belongs to the heme-copper respiratory oxidase family
CCX87_RS11660	COG2217	Heavy metal translocating P-type atpase
CCX87_RS11670	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS11690	COG1802	Transcriptional regulator
CCX87_RS11700	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CCX87_RS11705	COG0129	dihydroxy-acid dehydratase activity
CCX87_RS11715	COG4654	Cytochrome c, class I
CCX87_RS11725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CCX87_RS11735	COG4175	Glycine betaine
CCX87_RS11740	COG4176	ABC-type proline glycine betaine transport system permease component
CCX87_RS11745	COG2113	Glycine betaine
CCX87_RS11750	COG0114	fumarate hydratase activity
CCX87_RS11760	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CCX87_RS11765	COG1451	nucleotide metabolic process
CCX87_RS11835	COG0629	single-stranded DNA binding
CCX87_RS11840	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX87_RS11845	COG0270	DNA (cytosine-5-)-methyltransferase activity
CCX87_RS12035	COG2003	Belongs to the UPF0758 family
CCX87_RS12100	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CCX87_RS12100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CCX87_RS12105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CCX87_RS12110	COG1252	NADH dehydrogenase
CCX87_RS12115	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CCX87_RS12175	COG0583	DNA-binding transcription factor activity
CCX87_RS12190	COG4584	PFAM Integrase catalytic
CCX87_RS12195	COG1484	DNA-dependent DNA replication
CCX87_RS12200	COG0583	DNA-binding transcription factor activity
CCX87_RS12215	COG0582	viral genome integration into host DNA
CCX87_RS12225	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCX87_RS12230	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CCX87_RS12235	COG0740	serine-type endopeptidase activity
CCX87_RS12240	COG0544	peptidyl-prolyl cis-trans isomerase activity
CCX87_RS12255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS12265	COG1760	l-serine dehydratase
CCX87_RS12270	COG1562	ergosterol biosynthetic process
CCX87_RS12275	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CCX87_RS12290	COG1011	Hydrolase
CCX87_RS12300	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
CCX87_RS12305	COG1067	ATP-dependent peptidase activity
CCX87_RS12360	COG4177	L-phenylalanine transmembrane transporter activity
CCX87_RS12370	COG0411	ABC transporter
CCX87_RS12395	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS12405	COG0642	Histidine kinase
CCX87_RS12410	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CCX87_RS12415	COG2801	Transposase and inactivated derivatives
CCX87_RS12425	COG0527	aspartate kinase activity
CCX87_RS12430	COG0037	tRNA processing
CCX87_RS12435	COG0825	malonyl-CoA metabolic process
CCX87_RS12445	COG0215	cysteine-tRNA ligase activity
CCX87_RS12460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CCX87_RS12465	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CCX87_RS12470	COG3228	Belongs to the MtfA family
CCX87_RS12480	COG3384	dioxygenase
CCX87_RS12495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CCX87_RS12505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CCX87_RS12575	COG0745	RESPONSE REGULATOR receiver
CCX87_RS12600	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CCX87_RS12620	COG0564	pseudouridine synthase activity
CCX87_RS12630	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CCX87_RS12660	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CCX87_RS12665	COG2918	glutathione biosynthetic process
CCX87_RS12670	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS12700	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
CCX87_RS12705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CCX87_RS12710	COG0436	Aminotransferase
CCX87_RS12715	COG0824	Thioesterase
CCX87_RS12750	COG0039	L-malate dehydrogenase activity
CCX87_RS12755	COG2188	Transcriptional regulator
CCX87_RS12770	COG1053	succinate dehydrogenase
CCX87_RS12775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CCX87_RS12780	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CCX87_RS12785	COG0372	Belongs to the citrate synthase family
CCX87_RS12795	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CCX87_RS12800	COG2194	sulfuric ester hydrolase activity
CCX87_RS12810	COG1115	amino acid carrier protein
CCX87_RS12815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCX87_RS12830	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS12845	COG1196	nuclear chromosome segregation
CCX87_RS12845	COG3264	Mechanosensitive ion channel
CCX87_RS12855	COG0123	including yeast histone deacetylase and acetoin utilization protein
CCX87_RS12860	COG0714	Associated with various cellular activities
CCX87_RS12875	COG2951	lytic endotransglycosylase activity
CCX87_RS12880	COG1131	(ABC) transporter
CCX87_RS12885	COG0842	Transport permease protein
CCX87_RS12890	COG0683	leucine binding
CCX87_RS12905	COG1136	(ABC) transporter
CCX87_RS12905	COG0577	efflux transmembrane transporter activity
CCX87_RS12910	COG1136	(ABC) transporter
CCX87_RS12910	COG0577	efflux transmembrane transporter activity
CCX87_RS12915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS12925	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CCX87_RS12940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCX87_RS12945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS12950	COG1116	anion transmembrane transporter activity
CCX87_RS12955	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CCX87_RS12960	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CCX87_RS12965	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CCX87_RS12970	COG3265	gluconokinase activity
CCX87_RS12975	COG1609	Transcriptional regulator
CCX87_RS12985	COG0517	IMP dehydrogenase activity
CCX87_RS12995	COG0385	Bile acid
CCX87_RS13000	COG0745	RESPONSE REGULATOR receiver
CCX87_RS13005	COG2205	protein histidine kinase activity
CCX87_RS13010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS13015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCX87_RS13025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCX87_RS13030	COG1484	DNA-dependent DNA replication
CCX87_RS13035	COG4584	PFAM Integrase catalytic
CCX87_RS13040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CCX87_RS13050	COG0243	molybdopterin cofactor binding
CCX87_RS13055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCX87_RS13070	COG2995	paraquat-inducible protein a
CCX87_RS13075	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CCX87_RS13075	COG3008	intermembrane lipid transfer
CCX87_RS13085	COG1607	acyl-coa hydrolase
CCX87_RS13090	COG2081	HI0933 family
CCX87_RS13100	COG0828	Belongs to the bacterial ribosomal protein bS21 family
CCX87_RS13110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CCX87_RS13115	COG0312	modulator of DNA gyrase
CCX87_RS13120	COG3028	Belongs to the UPF0307 family
CCX87_RS13125	COG0521	Mo-molybdopterin cofactor biosynthetic process
CCX87_RS13130	COG1063	alcohol dehydrogenase
CCX87_RS13135	COG1045	serine acetyltransferase
CCX87_RS13145	COG0483	inositol monophosphate 1-phosphatase activity
CCX87_RS13150	COG3437	response regulator, receiver
CCX87_RS13150	COG2770	Histidine kinase
CCX87_RS13155	COG0784	Response regulator, receiver
CCX87_RS13155	COG2205	protein histidine kinase activity
CCX87_RS13155	COG5002	protein histidine kinase activity
CCX87_RS13190	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CCX87_RS13195	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CCX87_RS13200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CCX87_RS13235	COG1968	undecaprenyl-diphosphatase activity
CCX87_RS13245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCX87_RS13265	COG1280	lysine exporter protein (LysE YggA)
CCX87_RS13270	COG0488	(ABC) transporter
CCX87_RS13280	COG3608	succinylglutamate desuccinylase aspartoacylase
CCX87_RS13280	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CCX87_RS13290	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CCX87_RS13300	COG1122	ATPase activity
CCX87_RS13325	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CCX87_RS13330	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
CCX87_RS13335	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CCX87_RS13345	COG1722	exodeoxyribonuclease VII activity
CCX87_RS13380	COG0628	permease
CCX87_RS13385	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CCX87_RS13390	COG0181	hydroxymethylbilane synthase activity
CCX87_RS13410	COG3038	cytochrome b561
CCX87_RS13415	COG2353	YceI-like domain
CCX87_RS13420	COG2353	YceI-like domain
CCX87_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS13430	COG0525	valine-tRNA ligase activity
CCX87_RS13435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CCX87_RS13440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CCX87_RS13445	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCX87_RS13470	COG0425	Belongs to the sulfur carrier protein TusA family
CCX87_RS13495	COG0583	DNA-binding transcription factor activity
CCX87_RS13500	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS13505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS13520	COG0784	Response regulator, receiver
CCX87_RS13520	COG0835	chemotaxis
CCX87_RS13555	COG0617	tRNA 3'-terminal CCA addition
CCX87_RS13565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CCX87_RS13570	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
CCX87_RS13600	COG0589	response to stress
CCX87_RS13610	COG0728	peptidoglycan biosynthetic process
CCX87_RS13615	COG0268	Binds directly to 16S ribosomal RNA
CCX87_RS13625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CCX87_RS13630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CCX87_RS13640	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
CCX87_RS13650	COG3483	tryptophan 2,3-dioxygenase activity
CCX87_RS13660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCX87_RS13665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CCX87_RS13670	COG2916	Histone family protein nucleoid-structuring protein H-NS
CCX87_RS13675	COG1253	flavin adenine dinucleotide binding
CCX87_RS13680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CCX87_RS13685	COG0513	Belongs to the DEAD box helicase family
CCX87_RS13690	COG2321	neutral zinc metallopeptidase
CCX87_RS13695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CCX87_RS13700	COG2423	ornithine cyclodeaminase activity
CCX87_RS13705	COG3706	GGDEF domain
CCX87_RS13710	COG0717	Belongs to the dCTP deaminase family
CCX87_RS13715	COG0402	S-adenosylhomocysteine deaminase activity
CCX87_RS13725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CCX87_RS13745	COG4603	Belongs to the binding-protein-dependent transport system permease family
CCX87_RS13750	COG3845	ABC transporter
CCX87_RS13765	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CCX87_RS13775	COG5001	Diguanylate cyclase
CCX87_RS13775	COG5002	protein histidine kinase activity
CCX87_RS13775	COG3447	MASE1 domain protein
CCX87_RS13805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCX87_RS13810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS13855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CCX87_RS13860	COG0280	phosphate acetyltransferase
CCX87_RS13860	COG0281	malic enzyme
CCX87_RS13875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS13880	COG1752	Esterase of the alpha-beta hydrolase superfamily
CCX87_RS13885	COG3622	Belongs to the hyi family
CCX87_RS13895	COG0829	nickel cation binding
CCX87_RS13925	COG4770	biotin carboxylase activity
CCX87_RS13930	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
CCX87_RS13935	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
CCX87_RS13940	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CCX87_RS13965	COG0784	Response regulator, receiver
CCX87_RS13965	COG2205	protein histidine kinase activity
CCX87_RS13965	COG5002	protein histidine kinase activity
CCX87_RS13970	COG0831	urea catabolic process
CCX87_RS13980	COG0832	Belongs to the urease beta subunit family
CCX87_RS13985	COG0804	urea catabolic process
CCX87_RS13990	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
CCX87_RS13995	COG0830	nickel cation binding
CCX87_RS14000	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CCX87_RS14010	COG1704	LemA family
CCX87_RS14015	COG2346	COG2346, Truncated hemoglobins
CCX87_RS14020	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CCX87_RS14045	COG0437	4 iron, 4 sulfur cluster binding
CCX87_RS14050	COG3383	formate dehydrogenase (NAD+) activity
CCX87_RS14050	COG0243	molybdopterin cofactor binding
CCX87_RS14080	COG3383	formate dehydrogenase (NAD+) activity
CCX87_RS14090	COG0489	protein tyrosine kinase activity
CCX87_RS14100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX87_RS14100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CCX87_RS14110	COG0659	secondary active sulfate transmembrane transporter activity
CCX87_RS14130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CCX87_RS14135	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CCX87_RS14155	COG0602	queuosine metabolic process
CCX87_RS14160	COG0720	synthase
CCX87_RS14165	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CCX87_RS14190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCX87_RS14205	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
CCX87_RS14210	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CCX87_RS14220	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
CCX87_RS14225	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
CCX87_RS14240	COG0588	phosphoglycerate mutase activity
CCX87_RS14245	COG0793	Belongs to the peptidase S41A family
CCX87_RS14250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CCX87_RS14260	COG2197	response regulator
CCX87_RS14290	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CCX87_RS14295	COG0742	ribosomal rna small subunit methyltransferase
CCX87_RS14300	COG0612	Peptidase, M16
CCX87_RS14305	COG0612	Peptidase, M16
CCX87_RS14315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CCX87_RS14325	COG1999	signal sequence binding
CCX87_RS14330	COG0109	protoheme IX farnesyltransferase activity
CCX87_RS14355	COG1845	cytochrome c oxidase, subunit III
CCX87_RS14365	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
CCX87_RS14370	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCX87_RS14385	COG2226	methyltransferase
CCX87_RS14390	COG1040	competence protein
CCX87_RS14395	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CCX87_RS14400	COG0583	DNA-binding transcription factor activity
CCX87_RS14415	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
CCX87_RS14420	COG1280	lysine exporter protein (LysE YggA)
CCX87_RS14445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCX87_RS14450	COG0183	Belongs to the thiolase family
CCX87_RS14455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CCX87_RS14465	COG1414	Transcriptional regulator
CCX87_RS14525	COG1178	ABC-type Fe3 transport system permease component
CCX87_RS14530	COG3842	ATPase activity
CCX87_RS14540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CCX87_RS14545	COG0540	Belongs to the ATCase OTCase family
CCX87_RS14550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CCX87_RS14555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CCX87_RS14560	COG1678	Uncharacterized ACR, COG1678
CCX87_RS14565	COG0415	Belongs to the DNA photolyase family
CCX87_RS14585	COG0835	chemotaxis
CCX87_RS14600	COG1773	rubredoxin
CCX87_RS14610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
CCX87_RS14620	COG0138	bifunctional purine biosynthesis protein purh
CCX87_RS14625	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CCX87_RS14630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CCX87_RS14640	COG1238	metal cluster binding
CCX87_RS14660	COG1136	(ABC) transporter
CCX87_RS14660	COG0577	efflux transmembrane transporter activity
CCX87_RS14670	COG0012	GTP binding
CCX87_RS14680	COG3217	Mosc domain protein beta barrel domain protein
CCX87_RS14680	COG0633	Ferredoxin
CCX87_RS14685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCX87_RS14695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CCX87_RS14700	COG1024	Enoyl-CoA hydratase
CCX87_RS14715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CCX87_RS14720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CCX87_RS14725	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
CCX87_RS14755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CCX87_RS14765	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CCX87_RS14775	COG2264	protein methyltransferase activity
CCX87_RS14780	COG0439	Biotin carboxylase
CCX87_RS14785	COG0511	ligase activity, forming carbon-carbon bonds
CCX87_RS14790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CCX87_RS14800	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCX87_RS14810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CCX87_RS14820	COG0312	modulator of DNA gyrase
CCX87_RS14825	COG3422	double-strand break repair
CCX87_RS14830	COG0772	Belongs to the SEDS family
CCX87_RS14835	COG4585	Histidine kinase
CCX87_RS14840	COG2197	response regulator
CCX87_RS14860	COG3150	esterase
CCX87_RS14870	COG0557	exoribonuclease II activity
CCX87_RS14880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CCX87_RS14885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CCX87_RS14900	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CCX87_RS14915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CCX87_RS14945	COG1132	(ABC) transporter
CCX87_RS14950	COG0189	ligase activity
CCX87_RS14950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCX87_RS14955	COG0189	ligase activity
CCX87_RS14955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCX87_RS14960	COG3045	CreA protein
CCX87_RS14970	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS14985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CCX87_RS14990	COG0459	protein refolding
CCX87_RS15000	COG1858	cytochrome C peroxidase
CCX87_RS15020	COG0642	Histidine kinase
CCX87_RS15025	COG0800	Aldolase
CCX87_RS15030	COG0129	dihydroxy-acid dehydratase activity
CCX87_RS15040	COG0166	Belongs to the GPI family
CCX87_RS15045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CCX87_RS15055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CCX87_RS15090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CCX87_RS15095	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS15100	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS15105	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCX87_RS15105	COG1024	Enoyl-CoA hydratase
CCX87_RS15110	COG0583	DNA-binding transcription factor activity
CCX87_RS15115	COG4608	Belongs to the ABC transporter superfamily
CCX87_RS15120	COG0444	Belongs to the ABC transporter superfamily
CCX87_RS15125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX87_RS15130	COG1484	DNA-dependent DNA replication
CCX87_RS15135	COG4584	PFAM Integrase catalytic
CCX87_RS15140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX87_RS15150	COG1473	amidohydrolase
CCX87_RS15170	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
CCX87_RS15175	COG1765	OsmC-like protein
CCX87_RS15180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CCX87_RS15185	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
CCX87_RS15250	COG0840	transmembrane signaling receptor activity
CCX87_RS15255	COG0840	transmembrane signaling receptor activity
CCX87_RS15260	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CCX87_RS15265	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
CCX87_RS15270	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CCX87_RS15280	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CCX87_RS15285	COG1181	Belongs to the D-alanine--D-alanine ligase family
CCX87_RS15290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CCX87_RS15295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CCX87_RS15300	COG0772	Belongs to the SEDS family
CCX87_RS15305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CCX87_RS15310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CCX87_RS15315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CCX87_RS15320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CCX87_RS15335	COG0275	rRNA processing
CCX87_RS15340	COG2001	Belongs to the MraZ family
CCX87_RS15345	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CCX87_RS15350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CCX87_RS15365	COG0523	cobalamin synthesis protein
CCX87_RS15375	COG0789	Transcriptional regulator
CCX87_RS15395	COG3706	GGDEF domain
CCX87_RS15405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CCX87_RS15415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CCX87_RS15420	COG0625	glutathione transferase activity
CCX87_RS15435	COG0583	DNA-binding transcription factor activity
CCX87_RS15440	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS15445	COG3473	Maleate cis-trans isomerase
CCX87_RS15450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CCX87_RS15470	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
CCX87_RS15475	COG0471	metal ion transport
CCX87_RS15480	COG0840	transmembrane signaling receptor activity
CCX87_RS15485	COG0501	Belongs to the peptidase M48B family
CCX87_RS15500	COG0418	dihydroorotase activity
CCX87_RS15505	COG1126	abc transporter atp-binding protein
CCX87_RS15510	COG0765	amino acid transport
CCX87_RS15515	COG0765	amino acid transport
CCX87_RS15525	COG0583	DNA-binding transcription factor activity
CCX87_RS15535	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
CCX87_RS15535	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
CCX87_RS15540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
CCX87_RS15545	COG0583	DNA-binding transcription factor activity
CCX87_RS15555	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS15565	COG1021	2,3-dihydroxybenzoate-AMP ligase
CCX87_RS15575	COG1620	l-lactate permease
CCX87_RS15580	COG2186	Transcriptional regulator
CCX87_RS15585	COG1304	FMN binding
CCX87_RS15590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CCX87_RS15595	COG5265	(ABC) transporter
CCX87_RS15610	COG1024	Enoyl-CoA hydratase
CCX87_RS15620	COG0183	Belongs to the thiolase family
CCX87_RS15630	COG1024	Enoyl-CoA hydratase
CCX87_RS15630	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCX87_RS15640	COG1960	acyl-CoA dehydrogenase activity
CCX87_RS15650	COG1309	transcriptional regulator
CCX87_RS15655	COG0642	Histidine kinase
CCX87_RS15660	COG0745	RESPONSE REGULATOR receiver
CCX87_RS15665	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
CCX87_RS15720	COG5640	endopeptidase activity
CCX87_RS15805	COG1215	transferase activity, transferring glycosyl groups
CCX87_RS15825	COG4771	TonB-dependent receptor
CCX87_RS15915	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CCX87_RS15935	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
CCX87_RS15940	COG0751	glycine-tRNA ligase activity
CCX87_RS15945	COG0752	glycyl-tRNA synthetase alpha subunit
CCX87_RS15955	COG4598	ABC transporter
CCX87_RS15960	COG0765	amino acid transport
CCX87_RS15965	COG0765	amino acid transport
CCX87_RS15970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CCX87_RS16005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
CCX87_RS16020	COG1522	sequence-specific DNA binding
CCX87_RS16030	COG3186	Phenylalanine-4-hydroxylase
CCX87_RS16035	COG2267	carboxylic ester hydrolase activity
CCX87_RS16040	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS16055	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CCX87_RS16065	COG0625	glutathione transferase activity
CCX87_RS16075	COG0617	tRNA 3'-terminal CCA addition
CCX87_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS16105	COG0037	tRNA processing
CCX87_RS16130	COG2255	four-way junction helicase activity
CCX87_RS16140	COG0632	four-way junction helicase activity
CCX87_RS16145	COG1702	phosphate starvation-inducible protein PhoH
CCX87_RS16150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CCX87_RS16155	COG0477	Major facilitator Superfamily
CCX87_RS16160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CCX87_RS16165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CCX87_RS16170	COG1845	cytochrome c oxidase, subunit III
CCX87_RS16175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CCX87_RS16190	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
CCX87_RS16195	COG0730	response to heat
CCX87_RS16200	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CCX87_RS16205	COG0589	response to stress
CCX87_RS16210	COG1490	D-aminoacyl-tRNA deacylase activity
CCX87_RS16215	COG0513	Belongs to the DEAD box helicase family
CCX87_RS16225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCX87_RS16230	COG1131	(ABC) transporter
CCX87_RS16235	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CCX87_RS16260	COG0446	pyridine nucleotide-disulphide oxidoreductase
CCX87_RS16265	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
CCX87_RS16270	COG1116	anion transmembrane transporter activity
CCX87_RS16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCX87_RS16275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS16280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CCX87_RS16295	COG0842	Transport permease protein
CCX87_RS16310	COG1250	3-hydroxyacyl-CoA dehydrogenase
CCX87_RS16315	COG1846	Transcriptional regulator
CCX87_RS16320	COG1764	response to oxidative stress
CCX87_RS16330	COG2815	serine threonine protein kinase
CCX87_RS16330	COG0515	serine threonine protein kinase
CCX87_RS16335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CCX87_RS16350	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CCX87_RS16355	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CCX87_RS16360	COG0583	DNA-binding transcription factor activity
CCX87_RS16375	COG0326	Molecular chaperone. Has ATPase activity
CCX87_RS16380	COG1187	pseudouridine synthase activity
CCX87_RS16400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CCX87_RS16405	COG1022	Amp-dependent synthetase and ligase
CCX87_RS16450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCX87_RS16460	COG2818	Glycosylase
CCX87_RS16490	COG1473	amidohydrolase
CCX87_RS16500	COG0243	molybdopterin cofactor binding
CCX87_RS16510	COG1979	alcohol dehydrogenase
CCX87_RS16535	COG3945	hemerythrin HHE cation binding domain
CCX87_RS16555	COG0288	reversible hydration of carbon dioxide
CCX87_RS16560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX87_RS16565	COG2181	nitrate reductase activity
CCX87_RS16570	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
CCX87_RS16575	COG1140	nitrate reductase beta subunit
CCX87_RS16580	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CCX87_RS16585	COG2223	nitrite transmembrane transporter activity
CCX87_RS16595	COG2197	response regulator
CCX87_RS16600	COG5002	protein histidine kinase activity
CCX87_RS16600	COG2205	protein histidine kinase activity
CCX87_RS16600	COG0784	Response regulator, receiver
CCX87_RS16605	COG5001	Diguanylate cyclase
CCX87_RS16615	COG0583	DNA-binding transcription factor activity
CCX87_RS16620	COG0277	FAD linked oxidase domain protein
CCX87_RS16625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CCX87_RS16630	COG0134	indole-3-glycerol-phosphate synthase activity
CCX87_RS16635	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CCX87_RS16640	COG0512	Glutamine amidotransferase of anthranilate synthase
CCX87_RS16690	COG0629	single-stranded DNA binding
CCX87_RS16695	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX87_RS16880	COG1569	PIN domain
CCX87_RS16885	COG3311	Transcriptional regulator
CCX87_RS16940	COG2003	Belongs to the UPF0758 family
CCX87_RS17025	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS17030	COG0842	Transport permease protein
CCX87_RS17030	COG1129	ABC transporter
CCX87_RS17035	COG0842	Transport permease protein
CCX87_RS17045	COG1028	Short-chain dehydrogenase reductase Sdr
CCX87_RS17065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX87_RS17070	COG0786	glutamate:sodium symporter activity
CCX87_RS17080	COG0589	response to stress
CCX87_RS17100	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCX87_RS17105	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CCX87_RS17110	COG0583	DNA-binding transcription factor activity
CCX87_RS17115	COG1396	sequence-specific DNA binding
CCX87_RS17125	COG0582	viral genome integration into host DNA
CCX87_RS17145	COG0546	phosphoglycolate phosphatase activity
CCX87_RS17175	COG2204	response regulator
CCX87_RS17180	COG2198	Histidine kinase
CCX87_RS17180	COG0643	Histidine kinase
CCX87_RS17200	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS17235	COG2076	Multidrug Resistance protein
CCX87_RS17240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CCX87_RS17240	COG0546	phosphoglycolate phosphatase activity
CCX87_RS17255	COG1215	transferase activity, transferring glycosyl groups
CCX87_RS17270	COG1216	Glycosyl transferase, family 2
CCX87_RS17315	COG0438	transferase activity, transferring glycosyl groups
CCX87_RS17320	COG0438	transferase activity, transferring glycosyl groups
CCX87_RS17325	COG0438	transferase activity, transferring glycosyl groups
CCX87_RS17330	COG0367	asparagine synthase
CCX87_RS17355	COG3409	Peptidoglycan-binding domain 1 protein
CCX87_RS17355	COG3267	Type II secretory pathway component ExeA
CCX87_RS17365	COG0489	protein tyrosine kinase activity
CCX87_RS17390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CCX87_RS17395	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CCX87_RS17400	COG2967	ApaG domain
CCX87_RS17415	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
CCX87_RS17440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CCX87_RS17445	COG1129	ABC transporter
CCX87_RS17445	COG0842	Transport permease protein
CCX87_RS17450	COG0842	Transport permease protein
CCX87_RS17460	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX87_RS17465	COG0589	response to stress
CCX87_RS17470	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CCX87_RS17480	COG0653	protein targeting
CCX87_RS17500	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
CCX87_RS17505	COG1137	ATPase activity
CCX87_RS17520	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CCX87_RS17525	COG0018	arginyl-trna synthetase
CCX87_RS17545	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CCX87_RS17555	COG2814	Major facilitator Superfamily
CCX87_RS17560	COG0121	glutamine amidotransferase
CCX87_RS17565	COG4372	Transposase
CCX87_RS17595	COG1047	Peptidyl-prolyl cis-trans
CCX87_RS17620	COG1012	belongs to the aldehyde dehydrogenase family
CCX87_RS17630	COG2850	peptidyl-arginine hydroxylation
CCX87_RS17635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CCX87_RS17645	COG4372	Transposase
CCX87_RS17665	COG2124	cytochrome p450
CCX87_RS17700	COG0583	DNA-binding transcription factor activity
CCX87_RS17720	COG4584	PFAM Integrase catalytic
CCX87_RS17725	COG1484	DNA-dependent DNA replication
CCX87_RS17750	COG4372	Transposase
CCX87_RS17790	COG0189	ligase activity
CCX87_RS17795	COG3135	benzoate transporter
CCX87_RS17800	COG3158	transport of potassium into the cell
CCX87_RS17810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CCX87_RS17820	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CCX87_RS17835	COG0010	Belongs to the arginase family
CCX87_RS17845	COG0495	leucyl-tRNA aminoacylation
CCX87_RS17860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
CCX87_RS17865	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CCX87_RS17870	COG0735	belongs to the Fur family
CCX87_RS17875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CCX87_RS17880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CCX87_RS17885	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
CCX87_RS17895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CCX87_RS17910	COG2137	regulation of response to DNA damage stimulus
CCX87_RS17915	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CCX87_RS17930	COG3181	Tripartite tricarboxylate transporter family receptor
CCX87_RS17945	COG0642	Histidine kinase
CCX87_RS17970	COG0551	DNA topoisomerase type I activity
CCX87_RS17970	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX87_RS17975	COG2365	Tyrosine phosphatase family
CCX87_RS18070	COG0529	Catalyzes the synthesis of activated sulfate
CCX87_RS18110	COG3148	PFAM DTW domain containing protein
CCX87_RS18125	COG3550	peptidyl-serine autophosphorylation
CCX87_RS18145	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CCX87_RS18155	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CCX87_RS18160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CCX87_RS18165	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CCX87_RS18170	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CCX87_RS18175	COG0006	proline dipeptidase activity
CCX87_RS18180	COG0469	pyruvate kinase activity
CCX87_RS18205	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CCX87_RS18210	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CCX87_RS18215	COG0318	PFAM AMP-dependent synthetase and ligase
CCX87_RS18220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CCX87_RS18225	COG0598	Magnesium transport protein CorA
CCX87_RS18240	COG1214	PFAM Peptidase M22, glycoprotease
CCX87_RS18255	COG0009	L-threonylcarbamoyladenylate synthase
CCX87_RS18260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CCX87_RS18270	COG3118	belongs to the thioredoxin family
CCX87_RS18275	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
CCX87_RS18280	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CCX87_RS18290	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CCX87_RS18305	COG0281	malic enzyme
CCX87_RS18305	COG0280	phosphate acetyltransferase
CCX87_RS18315	COG0154	amidase activity
CCX87_RS18320	COG0444	Belongs to the ABC transporter superfamily
CCX87_RS18325	COG4608	Belongs to the ABC transporter superfamily
CCX87_RS18330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CCX87_RS18335	COG0601	transmembrane transport
CCX87_RS18390	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CCX87_RS18405	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CCX87_RS18430	COG0307	riboflavin synthase, alpha
CCX87_RS18450	COG1053	succinate dehydrogenase
CCX87_RS18450	COG3976	FMN-binding domain protein
CCX87_RS18465	COG1061	Type III restriction enzyme res subunit
CCX87_RS18470	COG0482	sulfurtransferase activity
CCX87_RS18475	COG0629	single-stranded DNA binding
CCX87_RS18480	COG2814	Major facilitator Superfamily
CCX87_RS18490	COG3284	Transcriptional regulator
CCX87_RS18495	COG1012	belongs to the aldehyde dehydrogenase family
CCX87_RS18505	COG0840	transmembrane signaling receptor activity
CCX87_RS18515	COG0697	spore germination
CCX87_RS18535	COG0284	orotidine-5'-phosphate decarboxylase activity
CCX87_RS18540	COG0126	phosphoglycerate kinase activity
CCX87_RS18555	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CCX87_RS18565	COG0242	peptide deformylase activity
CCX87_RS18570	COG1652	LysM domain
CCX87_RS18575	COG0758	DNA mediated transformation
CCX87_RS18585	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCX87_RS18590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CCX87_RS18595	COG1862	Preprotein translocase
CCX87_RS18605	COG1522	sequence-specific DNA binding
CCX87_RS18610	COG2814	Major facilitator Superfamily
CCX87_RS18645	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CCX87_RS18655	COG0625	glutathione transferase activity
CCX87_RS18675	COG0861	Integral membrane protein TerC family
CCX87_RS18685	COG1950	PFAM Membrane protein of
CCX87_RS18695	COG0315	cyclic pyranopterin monophosphate synthase activity
CCX87_RS18700	COG4636	protein conserved in cyanobacteria
CCX87_RS18710	COG3609	addiction module antidote protein, CC2985 family
CCX87_RS18720	COG4969	Belongs to the N-Me-Phe pilin family
CCX87_RS18760	COG1487	ribonuclease activity
CCX87_RS18770	COG1234	tRNA 3'-trailer cleavage
CCX87_RS18775	COG1716	ATPase activity
CCX87_RS18780	COG0631	protein serine/threonine phosphatase activity
CCX87_RS18795	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CCX87_RS18800	COG0045	succinate-CoA ligase (ADP-forming) activity
CCX87_RS18805	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CCX87_RS18825	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
CCX87_RS18840	COG3154	lipid carrier protein
CCX87_RS18845	COG0826	peptidase U32
CCX87_RS18850	COG0826	peptidase U32
CCX87_RS18860	COG2175	clavaminate synthase activity
CCX87_RS18875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CCX87_RS18880	COG2267	carboxylic ester hydrolase activity
CCX87_RS18890	COG0840	transmembrane signaling receptor activity
CCX87_RS18895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCX87_RS18895	COG2813	Specifically methylates the guanine in position
CCX87_RS18900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CCX87_RS18905	COG2119	membrane
CCX87_RS18910	COG0724	RNA recognition motif
CCX87_RS18915	COG0724	RNA recognition motif
CCX87_RS18920	COG4221	oxidoreductase activity
CCX87_RS18930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CCX87_RS18950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CCX87_RS18970	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CCX87_RS18980	COG0706	membrane insertase activity
CCX87_RS18985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
CCX87_RS18990	COG0594	ribonuclease P activity
CCX87_RS18995	COG0230	Belongs to the bacterial ribosomal protein bL34 family
CCX87_RS19015	COG2326	polyphosphate kinase activity
CCX87_RS19035	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CCX87_RS19045	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
CCX87_RS19050	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
CCX87_RS19075	COG2226	methyltransferase
CCX87_RS19080	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CCX87_RS19100	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
CCX87_RS19110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CCX87_RS19115	COG0789	Transcriptional regulator
CCX87_RS19120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CCX87_RS19125	COG1677	Flagellar hook-basal body complex protein FliE
CCX87_RS19135	COG4584	PFAM Integrase catalytic
CCX87_RS19140	COG1484	DNA-dependent DNA replication
CCX87_RS19170	COG1484	DNA-dependent DNA replication
CCX87_RS19230	COG1192	Involved in chromosome partitioning
CCX87_RS19270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CCX87_RS19275	COG1061	Type III restriction enzyme res subunit
CCX87_RS19280	COG1002	Type II restriction enzyme, methylase subunits
CCX87_RS19290	COG4691	Plasmid stability protein
CCX87_RS19305	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CCX87_RS19350	COG0433	COG0433 Predicted ATPase
CCX87_RS19425	COG4974	Belongs to the 'phage' integrase family
CCX87_RS19445	COG1484	DNA-dependent DNA replication
CCX87_RS19450	COG4584	PFAM Integrase catalytic
CCX87_RS19475	COG1396	sequence-specific DNA binding
CCX87_RS19480	COG3550	peptidyl-serine autophosphorylation
CCX87_RS19505	COG2205	protein histidine kinase activity
CCX87_RS19535	COG2217	Heavy metal translocating P-type atpase
CCX87_RS19565	COG1742	UPF0060 membrane protein
CCX87_RS19570	COG0789	Transcriptional regulator
CCX87_RS19590	COG3174	membrane
CCX87_RS19610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CCX87_RS19640	COG1484	DNA-dependent DNA replication
CCX87_RS19645	COG4584	PFAM Integrase catalytic
CCX87_RS19655	COG4974	Belongs to the 'phage' integrase family
CCX87_RS19660	COG0464	growth
CCX87_RS19675	COG4584	PFAM Integrase catalytic
CCX87_RS19680	COG1484	DNA-dependent DNA replication
CCX87_RS19765	COG2010	Cytochrome c
CCX87_RS19815	COG2855	membrane
CCX87_RS19845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CCX87_RS19985	COG4962	Type ii secretion system protein e
CCX87_RS19990	COG3838	Conjugal transfer protein Trbc
CCX87_RS19995	COG5268	conjugation
CCX87_RS20000	COG3451	type IV secretory pathway VirB4
CCX87_RS20080	COG2337	Toxic component of a toxin-antitoxin (TA) module
CCX87_RS20085	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCX87_RS20105	COG3639	organic phosphonate transmembrane transporter activity
CCX87_RS20110	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
CCX87_RS20115	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CCX87_RS20130	COG3454	Phosphonate metabolism
CCX87_RS20135	COG4778	phosphonate C-P lyase system protein PhnL
CCX87_RS20140	COG4107	phosphonate C-P lyase system protein PhnK
CCX87_RS20150	COG3627	carbon phosphorus lyase activity
CCX87_RS20155	COG3626	phosphonate metabolism
CCX87_RS20165	COG3624	Phosphonate C-P lyase system protein PhnG
CCX87_RS20170	COG2188	Transcriptional regulator
CCX87_RS20175	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
CCX87_RS20190	COG1414	Transcriptional regulator
CCX87_RS20200	COG0346	lactoylglutathione lyase activity
CCX87_RS20205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CCX87_RS20220	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CCX87_RS20225	COG0803	Belongs to the bacterial solute-binding protein 9 family
CCX87_RS20260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CCX87_RS20320	COG1573	uracil-dna glycosylase
CCX87_RS20325	COG1573	uracil-dna glycosylase
CCX87_RS20355	COG0789	Transcriptional regulator
CCX87_RS20365	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCX87_RS20465	COG1522	sequence-specific DNA binding
CCX87_RS20485	COG1484	DNA-dependent DNA replication
CCX87_RS20490	COG4584	PFAM Integrase catalytic
CCX87_RS20505	COG1049	propionate catabolic process, 2-methylcitrate cycle
CCX87_RS20540	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CCX87_RS20570	COG3284	Transcriptional regulator