locus-tag	class	description
YS110_RS00005	COG0582	viral genome integration into host DNA
YS110_RS00010	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
YS110_RS00140	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
YS110_RS00145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YS110_RS00165	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YS110_RS00180	COG1492	cobalamin metabolic process
YS110_RS00190	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
YS110_RS00200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YS110_RS00210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS00215	COG2900	Belongs to the SlyX family
YS110_RS00225	COG3530	Putative quorum-sensing-regulated virulence factor
YS110_RS00235	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
YS110_RS00240	COG1959	2 iron, 2 sulfur cluster binding
YS110_RS00245	COG0583	DNA-binding transcription factor activity
YS110_RS00260	COG0560	Phosphoserine phosphatase
YS110_RS00300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YS110_RS00305	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YS110_RS00305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YS110_RS00310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
YS110_RS00330	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS00340	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YS110_RS00355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YS110_RS00355	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
YS110_RS00360	COG2860	membrane
YS110_RS00365	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
YS110_RS00370	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YS110_RS00375	COG0431	NADPH-dependent FMN reductase
YS110_RS00380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_RS00390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_RS00395	COG1116	anion transmembrane transporter activity
YS110_RS00405	COG0583	DNA-binding transcription factor activity
YS110_RS00415	COG1045	serine acetyltransferase
YS110_RS00420	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS00425	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YS110_RS00440	COG0688	phosphatidylethanolamine metabolic process
YS110_RS00445	COG1125	glycine betaine transport
YS110_RS00445	COG0517	IMP dehydrogenase activity
YS110_RS00450	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YS110_RS00460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YS110_RS00475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS00480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_RS00495	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_RS00505	COG2917	probably involved in intracellular septation
YS110_RS00510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YS110_RS00515	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
YS110_RS00520	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS00530	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS00540	COG0559	Belongs to the binding-protein-dependent transport system permease family
YS110_RS00550	COG0411	ABC transporter
YS110_RS00560	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_RS00560	COG1024	Enoyl-CoA hydratase
YS110_RS00565	COG0183	Belongs to the thiolase family
YS110_RS00570	COG1305	Transglutaminase-like
YS110_RS00600	COG2308	Evidence 4 Homologs of previously reported genes of
YS110_RS00620	COG0670	Belongs to the BI1 family
YS110_RS00625	COG3193	protein, possibly involved in utilization of glycolate and propanediol
YS110_RS00630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
YS110_RS00640	COG0322	excinuclease ABC activity
YS110_RS00650	COG0776	regulation of translation
YS110_RS00660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_RS00690	COG4774	siderophore transport
YS110_RS00720	COG0347	Belongs to the P(II) protein family
YS110_RS00730	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YS110_RS00750	COG1595	DNA-templated transcription, initiation
YS110_RS00755	COG0028	Belongs to the TPP enzyme family
YS110_RS00760	COG0440	acetolactate synthase activity
YS110_RS00765	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
YS110_RS00770	COG1183	phosphatidylcholine synthase activity
YS110_RS00775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_RS00785	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YS110_RS00790	COG1320	monovalent cation:proton antiporter activity
YS110_RS00795	COG2212	antiporter activity
YS110_RS00805	COG0651	ATP synthesis coupled electron transport
YS110_RS00810	COG1006	Multisubunit Na H antiporter MnhC subunit
YS110_RS00815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YS110_RS00815	COG2111	Na H antiporter
YS110_RS00825	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YS110_RS00835	COG0776	regulation of translation
YS110_RS00845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
YS110_RS00850	COG0287	Prephenate dehydrogenase
YS110_RS00855	COG0077	Prephenate dehydratase
YS110_RS00855	COG1605	Chorismate mutase
YS110_RS00860	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
YS110_RS00875	COG1024	Enoyl-CoA hydratase
YS110_RS00885	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
YS110_RS00890	COG2867	negative regulation of translational initiation
YS110_RS00910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
YS110_RS00910	COG0519	Catalyzes the synthesis of GMP from XMP
YS110_RS00915	COG0582	viral genome integration into host DNA
YS110_RS00970	COG2003	Belongs to the UPF0758 family
YS110_RS01005	COG5489	Protein of unknown function (DUF736)
YS110_RS01035	COG1192	Involved in chromosome partitioning
YS110_RS01050	COG4959	Type IV secretory pathway protease TraF
YS110_RS01070	COG1902	pentaerythritol trinitrate reductase activity
YS110_RS01075	COG1335	isochorismatase
YS110_RS01095	COG0156	8-amino-7-oxononanoate synthase activity
YS110_RS01110	COG0367	asparagine synthase
YS110_RS01120	COG0583	DNA-binding transcription factor activity
YS110_RS01140	COG4962	Type ii secretion system protein e
YS110_RS01145	COG3838	Conjugal transfer protein Trbc
YS110_RS01155	COG3451	type IV secretory pathway VirB4
YS110_RS01170	COG3846	protein secretion by the type IV secretion system
YS110_RS01180	COG3504	Conjugal transfer protein
YS110_RS01240	COG1840	ABC-type Fe3 transport system, periplasmic component
YS110_RS01255	COG2832	Protein of unknown function (DUF454)
YS110_RS01260	COG0242	peptide deformylase activity
YS110_RS01275	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
YS110_RS01285	COG0047	phosphoribosylformylglycinamidine synthase activity
YS110_RS01285	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
YS110_RS01290	COG2354	Protein conserved in bacteria
YS110_RS01295	COG3047	cAMP biosynthetic process
YS110_RS01310	COG0826	peptidase U32
YS110_RS01315	COG0590	tRNA wobble adenosine to inosine editing
YS110_RS01330	COG1619	proteins homologs of microcin C7 resistance protein MccF
YS110_RS01335	COG3621	Patatin-like phospholipase
YS110_RS01360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS01375	COG2022	thiamine diphosphate biosynthetic process
YS110_RS01390	COG0351	phosphomethylpyrimidine kinase
YS110_RS01395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_RS01395	COG2755	lipolytic protein G-D-S-L family
YS110_RS01400	COG0471	metal ion transport
YS110_RS01415	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YS110_RS01425	COG0492	ferredoxin-NADP+ reductase activity
YS110_RS01430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
YS110_RS01435	COG0529	Catalyzes the synthesis of activated sulfate
YS110_RS01435	COG2895	sulfate adenylyltransferase (ATP) activity
YS110_RS01440	COG0175	sulfate reduction
YS110_RS01445	COG0175	sulfate reduction
YS110_RS01460	COG0730	response to heat
YS110_RS01465	COG0534	Mate efflux family protein
YS110_RS01480	COG0254	rRNA binding
YS110_RS01500	COG1024	Enoyl-CoA hydratase
YS110_RS01510	COG3712	iron ion homeostasis
YS110_RS01515	COG1595	DNA-templated transcription, initiation
YS110_RS01525	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YS110_RS01545	COG1074	ATP-dependent DNA helicase activity
YS110_RS01570	COG4206	TonB-dependent receptor
YS110_RS01580	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YS110_RS01585	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS01590	COG1120	ATPase activity
YS110_RS01595	COG4106	trans-aconitate 2-methyltransferase activity
YS110_RS01605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS01610	COG1120	ATPase activity
YS110_RS01630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS01635	COG1120	ATPase activity
YS110_RS01645	COG2226	methyltransferase
YS110_RS01650	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YS110_RS01685	COG0471	metal ion transport
YS110_RS01685	COG0490	domain, Protein
YS110_RS01705	COG0438	transferase activity, transferring glycosyl groups
YS110_RS01705	COG1216	Glycosyl transferase, family 2
YS110_RS01825	COG4397	Mu-like prophage major head subunit gpT
YS110_RS01835	COG4388	Caudovirus prohead serine protease
YS110_RS01855	COG2974	May be involved in recombination
YS110_RS02000	COG4373	Mu-like prophage FluMu protein gp28
YS110_RS02005	COG4383	Mu-like prophage protein gp29
YS110_RS02010	COG2369	cell adhesion
YS110_RS02060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YS110_RS02070	COG0835	chemotaxis
YS110_RS02075	COG0840	transmembrane signaling receptor activity
YS110_RS02125	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
YS110_RS02130	COG0583	DNA-binding transcription factor activity
YS110_RS02140	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YS110_RS02140	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YS110_RS02150	COG0052	Belongs to the universal ribosomal protein uS2 family
YS110_RS02155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
YS110_RS02160	COG0528	UMP kinase activity
YS110_RS02165	COG0233	cytoplasmic translational termination
YS110_RS02170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YS110_RS02175	COG0575	Belongs to the CDS family
YS110_RS02180	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
YS110_RS02185	COG0750	zinc metalloprotease
YS110_RS02200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_RS02205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YS110_RS02210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_RS02215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_RS02220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
YS110_RS02225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YS110_RS02230	COG0505	Belongs to the CarA family
YS110_RS02235	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YS110_RS02240	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_RS02260	COG1534	Rna-binding protein
YS110_RS02265	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
YS110_RS02270	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YS110_RS02275	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YS110_RS02280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
YS110_RS02295	COG0567	Dehydrogenase, E1 component
YS110_RS02300	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_RS02305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_RS02310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YS110_RS02320	COG0631	protein serine/threonine phosphatase activity
YS110_RS02325	COG1199	ATP-dependent helicase activity
YS110_RS02330	COG1595	DNA-templated transcription, initiation
YS110_RS02335	COG3712	iron ion homeostasis
YS110_RS02350	COG1487	ribonuclease activity
YS110_RS02355	COG4118	positive regulation of growth
YS110_RS02375	COG1487	ribonuclease activity
YS110_RS02385	COG1283	sodium-dependent phosphate transmembrane transporter activity
YS110_RS02390	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
YS110_RS02415	COG0433	COG0433 Predicted ATPase
YS110_RS02420	COG0217	transcriptional regulatory protein
YS110_RS02425	COG0151	Belongs to the GarS family
YS110_RS02430	COG0408	coproporphyrinogen oxidase activity
YS110_RS02435	COG0799	negative regulation of ribosome biogenesis
YS110_RS02440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
YS110_RS02445	COG0424	maF-like protein
YS110_RS02460	COG0714	Associated with various cellular activities
YS110_RS02480	COG1845	cytochrome c oxidase, subunit III
YS110_RS02485	COG2010	Cytochrome c
YS110_RS02490	COG0535	radical SAM domain protein
YS110_RS02510	COG3391	amine dehydrogenase activity
YS110_RS02515	COG2010	Cytochrome c
YS110_RS02525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YS110_RS02525	COG1648	precorrin-2 dehydrogenase activity
YS110_RS02530	COG1530	ribonuclease E activity
YS110_RS02565	COG0697	spore germination
YS110_RS02575	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_RS02590	COG0791	NLP P60 protein
YS110_RS02600	COG0205	6-phosphofructokinase activity
YS110_RS02605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_RS02625	COG2169	Transcriptional regulator
YS110_RS02655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YS110_RS02675	COG0589	response to stress
YS110_RS02685	COG0183	Belongs to the thiolase family
YS110_RS02695	COG0564	pseudouridine synthase activity
YS110_RS02710	COG0436	Aminotransferase
YS110_RS02715	COG0583	DNA-binding transcription factor activity
YS110_RS02735	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
YS110_RS02750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YS110_RS02760	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
YS110_RS02765	COG0252	asparaginase activity
YS110_RS02790	COG3712	iron ion homeostasis
YS110_RS02795	COG1595	DNA-templated transcription, initiation
YS110_RS02800	COG0563	adenylate kinase activity
YS110_RS02805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
YS110_RS02810	COG2835	tetraacyldisaccharide 4'-kinase activity
YS110_RS02815	COG1663	tetraacyldisaccharide 4'-kinase activity
YS110_RS02820	COG0848	biopolymer transport protein
YS110_RS02825	COG0811	peptide transport
YS110_RS02830	COG1570	exodeoxyribonuclease VII activity
YS110_RS02835	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YS110_RS02875	COG3712	iron ion homeostasis
YS110_RS02890	COG0133	tryptophan synthase activity
YS110_RS02910	COG1960	acyl-CoA dehydrogenase activity
YS110_RS02940	COG1113	amino acid transport
YS110_RS02950	COG1196	nuclear chromosome segregation
YS110_RS02965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YS110_RS03010	COG3243	poly(R)-hydroxyalkanoic acid synthase
YS110_RS03015	COG0183	Belongs to the thiolase family
YS110_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS03030	COG4804	nuclease activity
YS110_RS03035	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YS110_RS03045	COG0431	NADPH-dependent FMN reductase
YS110_RS03050	COG1393	Belongs to the ArsC family
YS110_RS03055	COG0798	PFAM Bile acid sodium symporter
YS110_RS03065	COG0640	Transcriptional regulator
YS110_RS03080	COG1475	DNA binding
YS110_RS03090	COG5489	Protein of unknown function (DUF736)
YS110_RS03095	COG1396	sequence-specific DNA binding
YS110_RS03135	COG4959	Type IV secretory pathway protease TraF
YS110_RS03155	COG0642	Histidine kinase
YS110_RS03165	COG3038	cytochrome b561
YS110_RS03195	COG2194	sulfuric ester hydrolase activity
YS110_RS03200	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YS110_RS03205	COG0583	DNA-binding transcription factor activity
YS110_RS03225	COG4962	Type ii secretion system protein e
YS110_RS03230	COG3838	Conjugal transfer protein Trbc
YS110_RS03240	COG3451	type IV secretory pathway VirB4
YS110_RS03255	COG3846	protein secretion by the type IV secretion system
YS110_RS03280	COG0488	(ABC) transporter
YS110_RS03285	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_RS03290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YS110_RS03300	COG2171	N-acyltransferase activity
YS110_RS03305	COG0436	Aminotransferase
YS110_RS03310	COG0840	transmembrane signaling receptor activity
YS110_RS03315	COG2878	Part of a membrane complex involved in electron transport
YS110_RS03330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YS110_RS03335	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YS110_RS03340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YS110_RS03345	COG2011	ABC-type metal ion transport system permease component
YS110_RS03350	COG1464	Belongs to the NlpA lipoprotein family
YS110_RS03370	COG3038	cytochrome b561
YS110_RS03380	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
YS110_RS03410	COG0259	pyridoxamine-phosphate oxidase activity
YS110_RS03425	COG1741	Belongs to the pirin family
YS110_RS03430	COG2353	YceI-like domain
YS110_RS03440	COG3038	cytochrome b561
YS110_RS03450	COG0346	lactoylglutathione lyase activity
YS110_RS03460	COG0243	molybdopterin cofactor binding
YS110_RS03480	COG1960	acyl-CoA dehydrogenase activity
YS110_RS03485	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS03495	COG4689	acetoacetate decarboxylase
YS110_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS03530	COG3781	membrane
YS110_RS03540	COG0640	Transcriptional regulator
YS110_RS03565	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_RS03580	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YS110_RS03600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
YS110_RS03615	COG4770	biotin carboxylase activity
YS110_RS03625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YS110_RS03630	COG1703	isobutyryl-CoA mutase activity
YS110_RS03640	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YS110_RS03640	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
YS110_RS03645	COG1802	Transcriptional regulator
YS110_RS03655	COG1022	Amp-dependent synthetase and ligase
YS110_RS03670	COG0488	(ABC) transporter
YS110_RS03675	COG0513	Belongs to the DEAD box helicase family
YS110_RS03685	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS03690	COG1643	Atp-dependent helicase
YS110_RS03700	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_RS03700	COG2755	lipolytic protein G-D-S-L family
YS110_RS03705	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
YS110_RS03705	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YS110_RS03725	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_RS03730	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
YS110_RS03735	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YS110_RS03740	COG4208	sulfate ABC transporter
YS110_RS03745	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YS110_RS03750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YS110_RS03765	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
YS110_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_RS03780	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_RS03785	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YS110_RS03795	COG4566	intracellular signal transduction
YS110_RS03800	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
YS110_RS03815	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YS110_RS03820	COG0167	dihydroorotate dehydrogenase activity
YS110_RS03865	COG0443	Heat shock 70 kDa protein
YS110_RS03880	COG0822	iron-sulfur transferase activity
YS110_RS03885	COG1104	cysteine desulfurase activity
YS110_RS03890	COG1959	2 iron, 2 sulfur cluster binding
YS110_RS03895	COG0556	nucleotide-excision repair
YS110_RS03905	COG1024	Enoyl-CoA hydratase
YS110_RS03950	COG3384	dioxygenase
YS110_RS03955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_RS03960	COG1278	Cold shock
YS110_RS04000	COG1739	Uncharacterized protein family UPF0029
YS110_RS04010	COG0501	Belongs to the peptidase M48B family
YS110_RS04030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YS110_RS04035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YS110_RS04055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
YS110_RS04065	COG4181	ATPase activity
YS110_RS04085	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
YS110_RS04115	COG1741	Belongs to the pirin family
YS110_RS04130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_RS04135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
YS110_RS04140	COG3706	GGDEF domain
YS110_RS04145	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YS110_RS04150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS04155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YS110_RS04160	COG3842	ATPase activity
YS110_RS04170	COG1176	ABC-type spermidine putrescine transport system, permease component I
YS110_RS04175	COG1177	transmembrane transport
YS110_RS04190	COG3971	2-oxopent-4-enoate hydratase activity
YS110_RS04195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YS110_RS04210	COG2267	carboxylic ester hydrolase activity
YS110_RS04230	COG0842	Transport permease protein
YS110_RS04235	COG0842	Transport permease protein
YS110_RS04235	COG1129	ABC transporter
YS110_RS04240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS04265	COG0583	DNA-binding transcription factor activity
YS110_RS04270	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
YS110_RS04275	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YS110_RS04285	COG2828	Protein conserved in bacteria
YS110_RS04305	COG1396	sequence-specific DNA binding
YS110_RS04305	COG3800	Transcriptional regulator
YS110_RS04340	COG4372	Transposase
YS110_RS04375	COG4282	regulation of fungal-type cell wall biogenesis
YS110_RS04415	COG0564	pseudouridine synthase activity
YS110_RS04420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_RS04425	COG2925	Exonuclease
YS110_RS04445	COG4774	siderophore transport
YS110_RS04450	COG2951	lytic endotransglycosylase activity
YS110_RS04475	COG0542	response to heat
YS110_RS04480	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
YS110_RS04535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YS110_RS04545	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
YS110_RS04560	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
YS110_RS04565	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
YS110_RS04570	COG1414	Transcriptional regulator
YS110_RS04590	COG2011	ABC-type metal ion transport system permease component
YS110_RS04595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
YS110_RS04600	COG1464	Belongs to the NlpA lipoprotein family
YS110_RS04605	COG1464	Belongs to the NlpA lipoprotein family
YS110_RS04615	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
YS110_RS04620	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
YS110_RS04630	COG1722	exodeoxyribonuclease VII activity
YS110_RS04675	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
YS110_RS04680	COG0181	hydroxymethylbilane synthase activity
YS110_RS04690	COG2959	enzyme of heme biosynthesis
YS110_RS04700	COG0114	fumarate hydratase activity
YS110_RS04705	COG0753	catalase activity
YS110_RS04725	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS04735	COG3033	Beta-eliminating lyase
YS110_RS04745	COG4120	Belongs to the binding-protein-dependent transport system permease family
YS110_RS04750	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
YS110_RS04755	COG0833	amino acid
YS110_RS04770	COG1487	ribonuclease activity
YS110_RS04780	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS04790	COG0583	DNA-binding transcription factor activity
YS110_RS04795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
YS110_RS04800	COG0509	glycine decarboxylation via glycine cleavage system
YS110_RS04805	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YS110_RS04805	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
YS110_RS04855	COG0545	Peptidyl-prolyl cis-trans isomerase
YS110_RS04875	COG0587	DNA-directed DNA polymerase activity
YS110_RS04995	COG0776	regulation of translation
YS110_RS05005	COG1204	response to ionizing radiation
YS110_RS05015	COG1403	HNH endonuclease
YS110_RS05030	COG2948	multi-organism process
YS110_RS05045	COG3846	protein secretion by the type IV secretion system
YS110_RS05060	COG3451	type IV secretory pathway VirB4
YS110_RS05075	COG4962	Type ii secretion system protein e
YS110_RS05090	COG0583	DNA-binding transcription factor activity
YS110_RS05100	COG0523	cobalamin synthesis protein
YS110_RS05120	COG0145	ligase activity
YS110_RS05125	COG4647	ligase activity
YS110_RS05130	COG0145	ligase activity
YS110_RS05140	COG1063	alcohol dehydrogenase
YS110_RS05165	COG1192	Involved in chromosome partitioning
YS110_RS05200	COG5489	Protein of unknown function (DUF736)
YS110_RS05210	COG1475	DNA binding
YS110_RS05245	COG1431	PFAM Stem cell self-renewal protein Piwi
YS110_RS05255	COG0514	ATP-dependent DNA helicase (RecQ)
YS110_RS05260	COG0582	viral genome integration into host DNA
YS110_RS05275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_RS05285	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YS110_RS05300	COG0823	Involved in the tonB-independent uptake of proteins
YS110_RS05305	COG1132	(ABC) transporter
YS110_RS05315	COG0084	hydrolase, TatD family'
YS110_RS05330	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
YS110_RS05335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YS110_RS05370	COG0657	acetylesterase activity
YS110_RS05385	COG1639	'signal transduction protein
YS110_RS05390	COG2183	response to ionizing radiation
YS110_RS05420	COG2130	NADP-dependent
YS110_RS05435	COG1960	acyl-CoA dehydrogenase activity
YS110_RS05440	COG0697	spore germination
YS110_RS05445	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_RS05445	COG1902	pentaerythritol trinitrate reductase activity
YS110_RS05495	COG0308	aminopeptidase N
YS110_RS05500	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
YS110_RS05510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YS110_RS05515	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YS110_RS05520	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
YS110_RS05525	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
YS110_RS05535	COG1388	LysM domain
YS110_RS05535	COG0741	lytic transglycosylase activity
YS110_RS05540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_RS05545	COG2226	methyltransferase
YS110_RS05550	COG0328	RNA-DNA hybrid ribonuclease activity
YS110_RS05555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YS110_RS05560	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YS110_RS05575	COG2850	peptidyl-arginine hydroxylation
YS110_RS05580	COG1047	Peptidyl-prolyl cis-trans
YS110_RS05600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_RS05605	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_RS05630	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
YS110_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YS110_RS05655	COG0557	exoribonuclease II activity
YS110_RS05680	COG0741	lytic transglycosylase activity
YS110_RS05685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
YS110_RS05690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YS110_RS05700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
YS110_RS05715	COG2267	carboxylic ester hydrolase activity
YS110_RS05720	COG1295	ribonuclease BN
YS110_RS05730	COG0277	FAD linked oxidase domain protein
YS110_RS05760	COG1595	DNA-templated transcription, initiation
YS110_RS05765	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
YS110_RS05800	COG0183	Belongs to the thiolase family
YS110_RS05835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_RS05860	COG0285	dihydrofolate synthase activity
YS110_RS05865	COG1393	Belongs to the ArsC family
YS110_RS05875	COG3123	guanosine phosphorylase activity
YS110_RS05880	COG0137	argininosuccinate synthase activity
YS110_RS05885	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YS110_RS05895	COG1595	DNA-templated transcription, initiation
YS110_RS05900	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YS110_RS05905	COG0583	DNA-binding transcription factor activity
YS110_RS05935	COG3712	iron ion homeostasis
YS110_RS05940	COG1595	DNA-templated transcription, initiation
YS110_RS05945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
YS110_RS05950	COG1666	GTP binding
YS110_RS05965	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
YS110_RS05985	COG3655	Transcriptional regulator
YS110_RS05995	COG0667	Aldo Keto reductase
YS110_RS06020	COG1192	Involved in chromosome partitioning
YS110_RS06130	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
YS110_RS06145	COG0784	Response regulator, receiver
YS110_RS06145	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YS110_RS06410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_RS06425	COG0741	lytic transglycosylase activity
YS110_RS06425	COG1196	nuclear chromosome segregation
YS110_RS06425	COG0739	heme binding
YS110_RS06590	COG0735	belongs to the Fur family
YS110_RS06610	COG0789	Transcriptional regulator
YS110_RS06615	COG0776	regulation of translation
YS110_RS06625	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YS110_RS06630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
YS110_RS06635	COG0291	Belongs to the bacterial ribosomal protein bL35 family
YS110_RS06640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
YS110_RS06645	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
YS110_RS06660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YS110_RS06695	COG1253	flavin adenine dinucleotide binding
YS110_RS06705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YS110_RS06710	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
YS110_RS06715	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
YS110_RS06720	COG0195	Participates in both transcription termination and antitermination
YS110_RS06725	COG0779	Required for maturation of 30S ribosomal subunits
YS110_RS06735	COG4771	TonB-dependent receptor
YS110_RS06745	COG0114	fumarate hydratase activity
YS110_RS06770	COG4172	Belongs to the ABC transporter superfamily
YS110_RS06775	COG4239	(ABC) transporter, permease
YS110_RS06800	COG4174	ABC transporter (Permease)
YS110_RS06815	COG4166	transmembrane transport
YS110_RS06820	COG0829	nickel cation binding
YS110_RS06855	COG2205	protein histidine kinase activity
YS110_RS06855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_RS06860	COG0831	urea catabolic process
YS110_RS06870	COG0832	Belongs to the urease beta subunit family
YS110_RS06875	COG0804	urea catabolic process
YS110_RS06885	COG0830	nickel cation binding
YS110_RS06890	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YS110_RS06900	COG2841	Protein conserved in bacteria
YS110_RS06905	COG1793	dna ligase
YS110_RS06930	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YS110_RS06935	COG0746	molybdenum cofactor guanylyltransferase activity
YS110_RS06955	COG1522	sequence-specific DNA binding
YS110_RS06960	COG5006	permease, DMT superfamily
YS110_RS06970	COG3039	Transposase
YS110_RS06990	COG1380	Effector of murein hydrolase LrgA
YS110_RS07000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS07005	COG1271	oxidase subunit
YS110_RS07010	COG1294	oxidase, subunit
YS110_RS07025	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
YS110_RS07055	COG1120	ATPase activity
YS110_RS07060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS07065	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
YS110_RS07080	COG4206	TonB-dependent receptor
YS110_RS07095	COG0730	response to heat
YS110_RS07105	COG3437	response regulator, receiver
YS110_RS07120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS07150	COG3278	Belongs to the heme-copper respiratory oxidase family
YS110_RS07160	COG2217	Heavy metal translocating P-type atpase
YS110_RS07175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YS110_RS07200	COG1525	nuclease
YS110_RS07205	COG0564	pseudouridine synthase activity
YS110_RS07210	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
YS110_RS07220	COG3850	Histidine kinase
YS110_RS07220	COG5002	protein histidine kinase activity
YS110_RS07225	COG1289	transmembrane transporter activity
YS110_RS07230	COG2918	glutathione biosynthetic process
YS110_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS07240	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YS110_RS07260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
YS110_RS07265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_RS07270	COG0436	Aminotransferase
YS110_RS07275	COG0824	Thioesterase
YS110_RS07295	COG0477	Major facilitator Superfamily
YS110_RS07305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YS110_RS07310	COG1845	cytochrome c oxidase, subunit III
YS110_RS07315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YS110_RS07330	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
YS110_RS07345	COG1595	DNA-templated transcription, initiation
YS110_RS07350	COG3712	iron ion homeostasis
YS110_RS07370	COG0826	peptidase U32
YS110_RS07375	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS07380	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YS110_RS07385	COG1960	acyl-CoA dehydrogenase activity
YS110_RS07390	COG1960	acyl-CoA dehydrogenase activity
YS110_RS07395	COG1024	Enoyl-CoA hydratase
YS110_RS07395	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_RS07400	COG0183	Belongs to the thiolase family
YS110_RS07410	COG1846	Transcriptional regulator
YS110_RS07420	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS07425	COG1024	Enoyl-CoA hydratase
YS110_RS07455	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YS110_RS07460	COG0604	alcohol dehydrogenase
YS110_RS07480	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS07495	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
YS110_RS07505	COG0655	NAD(P)H dehydrogenase (quinone) activity
YS110_RS07510	COG0129	dihydroxy-acid dehydratase activity
YS110_RS07520	COG4654	Cytochrome c, class I
YS110_RS07525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_RS07530	COG4175	Glycine betaine
YS110_RS07535	COG4176	ABC-type proline glycine betaine transport system permease component
YS110_RS07540	COG2113	Glycine betaine
YS110_RS07550	COG1742	UPF0060 membrane protein
YS110_RS07570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS07580	COG3278	Belongs to the heme-copper respiratory oxidase family
YS110_RS07605	COG4585	Histidine kinase
YS110_RS07635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YS110_RS07645	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS07650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YS110_RS07655	COG0508	dehydrogenase complex catalyzes the overall conversion of
YS110_RS07665	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
YS110_RS07670	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS07700	COG2186	Transcriptional regulator
YS110_RS07710	COG0525	valine-tRNA ligase activity
YS110_RS07715	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YS110_RS07735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YS110_RS07770	COG0425	Belongs to the sulfur carrier protein TusA family
YS110_RS07795	COG0415	Belongs to the DNA photolyase family
YS110_RS07800	COG0625	glutathione transferase activity
YS110_RS07805	COG0583	DNA-binding transcription factor activity
YS110_RS07810	COG1960	acyl-CoA dehydrogenase activity
YS110_RS07815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_RS07835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_RS07855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YS110_RS07860	COG0840	transmembrane signaling receptor activity
YS110_RS07875	COG5001	Diguanylate cyclase
YS110_RS07880	COG1968	undecaprenyl-diphosphatase activity
YS110_RS07885	COG3275	phosphorelay sensor kinase activity
YS110_RS07890	COG3279	Response regulator of the LytR AlgR family
YS110_RS07960	COG3268	Saccharopine dehydrogenase
YS110_RS07990	COG0756	dUTP diphosphatase activity
YS110_RS07995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YS110_RS08000	COG0504	CTP synthase activity
YS110_RS08005	COG2877	3-deoxy-8-phosphooctulonate synthase activity
YS110_RS08010	COG0148	phosphopyruvate hydratase activity
YS110_RS08015	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
YS110_RS08020	COG4770	biotin carboxylase activity
YS110_RS08030	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
YS110_RS08035	COG0024	Methionine aminopeptidase
YS110_RS08080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
YS110_RS08090	COG2833	Protein of unknown function (DUF455)
YS110_RS08095	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
YS110_RS08100	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
YS110_RS08105	COG4974	Belongs to the 'phage' integrase family
YS110_RS08130	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YS110_RS08135	COG0802	atpase or kinase
YS110_RS08140	COG0860	N-Acetylmuramoyl-L-alanine amidase
YS110_RS08145	COG0668	transmembrane transport
YS110_RS08155	COG0586	Pfam SNARE associated Golgi protein
YS110_RS08160	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
YS110_RS08165	COG0745	RESPONSE REGULATOR receiver
YS110_RS08195	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YS110_RS08200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
YS110_RS08245	COG1007	ATP synthesis coupled electron transport
YS110_RS08260	COG0713	ATP synthesis coupled electron transport
YS110_RS08270	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_RS08275	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
YS110_RS08280	COG1034	ATP synthesis coupled electron transport
YS110_RS08295	COG0649	NAD binding
YS110_RS08300	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_RS08305	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_RS08310	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YS110_RS08325	COG0149	triose-phosphate isomerase activity
YS110_RS08330	COG0604	alcohol dehydrogenase
YS110_RS08335	COG1185	polyribonucleotide nucleotidyltransferase activity
YS110_RS08340	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
YS110_RS08345	COG0719	Fe-S assembly protein
YS110_RS08350	COG0396	ATPase activity
YS110_RS08365	COG0822	iron-sulfur transferase activity
YS110_RS08370	COG2151	metal-sulfur cluster biosynthetic enzyme
YS110_RS08390	COG4969	Belongs to the N-Me-Phe pilin family
YS110_RS08425	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YS110_RS08425	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YS110_RS08430	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
YS110_RS08435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YS110_RS08440	COG2264	protein methyltransferase activity
YS110_RS08455	COG2197	response regulator
YS110_RS08460	COG0784	Response regulator, receiver
YS110_RS08460	COG2198	Histidine kinase
YS110_RS08460	COG2205	protein histidine kinase activity
YS110_RS08480	COG0542	response to heat
YS110_RS08485	COG0314	molybdopterin synthase activity
YS110_RS08510	COG0303	'Molybdopterin
YS110_RS08515	COG1763	Mo-molybdopterin cofactor biosynthetic process
YS110_RS08530	COG0436	Aminotransferase
YS110_RS08540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YS110_RS08545	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
YS110_RS08575	COG0084	hydrolase, TatD family'
YS110_RS08580	COG1136	(ABC) transporter
YS110_RS08585	COG4591	ABC-type transport system involved in lipoprotein release permease component
YS110_RS08595	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YS110_RS08605	COG0840	transmembrane signaling receptor activity
YS110_RS08610	COG0840	transmembrane signaling receptor activity
YS110_RS08615	COG0613	PHP domain protein
YS110_RS08620	COG0009	L-threonylcarbamoyladenylate synthase
YS110_RS08625	COG1994	Peptidase M50
YS110_RS08630	COG0180	Tryptophanyl-tRNA synthetase
YS110_RS08635	COG0745	RESPONSE REGULATOR receiver
YS110_RS08665	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
YS110_RS08730	COG3148	PFAM DTW domain containing protein
YS110_RS08740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
YS110_RS08750	COG0784	Response regulator, receiver
YS110_RS08750	COG2205	protein histidine kinase activity
YS110_RS08750	COG5002	protein histidine kinase activity
YS110_RS08765	COG0784	Response regulator, receiver
YS110_RS08765	COG3437	response regulator, receiver
YS110_RS08805	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
YS110_RS08810	COG1047	Peptidyl-prolyl cis-trans
YS110_RS08815	COG2003	Belongs to the UPF0758 family
YS110_RS08820	COG1840	ABC-type Fe3 transport system, periplasmic component
YS110_RS08825	COG1178	ABC-type Fe3 transport system permease component
YS110_RS08840	COG5002	protein histidine kinase activity
YS110_RS08850	COG4680	protein conserved in bacteria
YS110_RS08870	COG3712	iron ion homeostasis
YS110_RS08905	COG1193	negative regulation of DNA recombination
YS110_RS08910	COG1846	Transcriptional regulator
YS110_RS08940	COG0501	Belongs to the peptidase M48B family
YS110_RS08945	COG1704	LemA family
YS110_RS08960	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YS110_RS08965	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
YS110_RS08975	COG0437	4 iron, 4 sulfur cluster binding
YS110_RS08980	COG2864	formate dehydrogenase
YS110_RS09025	COG3276	selenocysteine insertion sequence binding
YS110_RS09075	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS09080	COG1960	acyl-CoA dehydrogenase activity
YS110_RS09110	COG0489	protein tyrosine kinase activity
YS110_RS09130	COG5002	protein histidine kinase activity
YS110_RS09130	COG2205	protein histidine kinase activity
YS110_RS09130	COG0784	Response regulator, receiver
YS110_RS09135	COG3706	GGDEF domain
YS110_RS09135	COG4251	negative regulation of phosphorylation
YS110_RS09135	COG5001	Diguanylate cyclase
YS110_RS09135	COG2203	Gaf domain
YS110_RS09140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YS110_RS09140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YS110_RS09180	COG2755	lipolytic protein G-D-S-L family
YS110_RS09225	COG3135	benzoate transporter
YS110_RS09235	COG0505	Belongs to the CarA family
YS110_RS09240	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
YS110_RS09250	COG0702	epimerase
YS110_RS09260	COG1073	alpha beta
YS110_RS09275	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_RS09310	COG0683	leucine binding
YS110_RS09340	COG4566	intracellular signal transduction
YS110_RS09395	COG0028	Belongs to the TPP enzyme family
YS110_RS09420	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YS110_RS09430	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
YS110_RS09445	COG0156	8-amino-7-oxononanoate synthase activity
YS110_RS09465	COG2204	response regulator
YS110_RS09480	COG0683	leucine binding
YS110_RS09520	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
YS110_RS09530	COG4133	protoheme IX ABC transporter activity
YS110_RS09540	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
YS110_RS09545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
YS110_RS09590	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
YS110_RS09595	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
YS110_RS09600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YS110_RS09610	COG0588	phosphoglycerate mutase activity
YS110_RS09615	COG0793	Belongs to the peptidase S41A family
YS110_RS09630	COG2197	response regulator
YS110_RS09635	COG4585	Histidine kinase
YS110_RS09640	COG5487	UPF0391 membrane protein
YS110_RS09690	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
YS110_RS09695	COG0742	ribosomal rna small subunit methyltransferase
YS110_RS09700	COG0612	Peptidase, M16
YS110_RS09705	COG0612	Peptidase, M16
YS110_RS09745	COG1730	sister chromatid segregation
YS110_RS09750	COG1858	cytochrome C peroxidase
YS110_RS09760	COG0484	heat shock protein binding
YS110_RS09765	COG3171	Protein conserved in bacteria
YS110_RS09770	COG1120	ATPase activity
YS110_RS09775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS09785	COG4774	siderophore transport
YS110_RS09810	COG1121	(ABC) transporter
YS110_RS09820	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YS110_RS09825	COG1999	signal sequence binding
YS110_RS09830	COG0109	protoheme IX farnesyltransferase activity
YS110_RS09860	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
YS110_RS09880	COG2226	methyltransferase
YS110_RS09885	COG1040	competence protein
YS110_RS09890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YS110_RS09900	COG0489	protein tyrosine kinase activity
YS110_RS09905	COG1280	lysine exporter protein (LysE YggA)
YS110_RS09910	COG0475	glutathione-regulated potassium exporter activity
YS110_RS09910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YS110_RS09930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YS110_RS09965	COG0724	RNA recognition motif
YS110_RS09970	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YS110_RS09980	COG0642	Histidine kinase
YS110_RS10005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_RS10010	COG1393	Belongs to the ArsC family
YS110_RS10015	COG1178	ABC-type Fe3 transport system permease component
YS110_RS10020	COG3842	ATPase activity
YS110_RS10035	COG0540	Belongs to the ATCase OTCase family
YS110_RS10040	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
YS110_RS10045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
YS110_RS10050	COG1678	Uncharacterized ACR, COG1678
YS110_RS10055	COG0643	Histidine kinase
YS110_RS10055	COG2198	Histidine kinase
YS110_RS10060	COG0840	transmembrane signaling receptor activity
YS110_RS10065	COG0835	chemotaxis
YS110_RS10080	COG1773	rubredoxin
YS110_RS10090	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
YS110_RS10115	COG2132	Multicopper oxidase
YS110_RS10135	COG0138	bifunctional purine biosynthesis protein purh
YS110_RS10140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YS110_RS10145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YS110_RS10150	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
YS110_RS10155	COG1238	metal cluster binding
YS110_RS10160	COG1420	regulation of RNA biosynthetic process
YS110_RS10165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YS110_RS10170	COG0497	DNA recombination
YS110_RS10175	COG1660	Displays ATPase and GTPase activities
YS110_RS10180	COG1194	a g-specific adenine glycosylase
YS110_RS10190	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
YS110_RS10205	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
YS110_RS10215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YS110_RS10220	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
YS110_RS10225	COG0193	aminoacyl-tRNA hydrolase activity
YS110_RS10230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YS110_RS10235	COG0601	transmembrane transport
YS110_RS10240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YS110_RS10245	COG0747	negative chemotaxis
YS110_RS10250	COG1280	lysine exporter protein (LysE YggA)
YS110_RS10265	COG3258	Cytochrome c
YS110_RS10270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_RS10275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
YS110_RS10280	COG4521	taurine ABC transporter
YS110_RS10305	COG0302	gtp cyclohydrolase
YS110_RS10335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YS110_RS10355	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
YS110_RS10370	COG2226	methyltransferase
YS110_RS10405	COG0745	RESPONSE REGULATOR receiver
YS110_RS10410	COG0642	Histidine kinase
YS110_RS10415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YS110_RS10425	COG1175	transmembrane transport
YS110_RS10430	COG0395	ABC-type sugar transport system, permease component
YS110_RS10435	COG3842	ATPase activity
YS110_RS10440	COG0584	glycerophosphoryl diester phosphodiesterase
YS110_RS10450	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
YS110_RS10455	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
YS110_RS10460	COG2890	protein-(glutamine-N5) methyltransferase activity
YS110_RS10465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YS110_RS10470	COG1253	flavin adenine dinucleotide binding
YS110_RS10480	COG0442	prolyl-tRNA aminoacylation
YS110_RS10485	COG0494	nUDIX hydrolase
YS110_RS10490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
YS110_RS10495	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
YS110_RS10500	COG0211	Belongs to the bacterial ribosomal protein bL27 family
YS110_RS10505	COG0261	This protein binds to 23S rRNA in the presence of protein L20
YS110_RS10510	COG0142	geranyltranstransferase activity
YS110_RS10530	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
YS110_RS10535	COG0237	dephospho-CoA kinase activity
YS110_RS10540	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
YS110_RS10545	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
YS110_RS10550	COG0494	nUDIX hydrolase
YS110_RS10560	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
YS110_RS10565	COG0653	protein targeting
YS110_RS10580	COG2969	positive regulation of protein catabolic process
YS110_RS10585	COG0625	glutathione transferase activity
YS110_RS10590	COG2857	Cytochrome c1
YS110_RS10595	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
YS110_RS10600	COG0723	plastoquinol--plastocyanin reductase activity
YS110_RS10605	COG1970	mechanosensitive ion channel activity
YS110_RS10610	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YS110_RS10615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YS110_RS10620	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_RS10625	COG0805	protein transport
YS110_RS10630	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YS110_RS10635	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YS110_RS10640	COG0537	adenosine 5'-monophosphoramidase activity
YS110_RS10655	COG0140	phosphoribosyl-ATP diphosphatase activity
YS110_RS10660	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YS110_RS10665	COG0107	imidazoleglycerol-phosphate synthase activity
YS110_RS10670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YS110_RS10700	COG0438	transferase activity, transferring glycosyl groups
YS110_RS10715	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
YS110_RS10725	COG0131	Imidazoleglycerol-phosphate dehydratase
YS110_RS10730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YS110_RS10750	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS10760	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YS110_RS10765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
YS110_RS10770	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
YS110_RS10780	COG0842	Transport permease protein
YS110_RS10785	COG1131	(ABC) transporter
YS110_RS10800	COG2853	Lipoprotein
YS110_RS10805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YS110_RS10810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YS110_RS10815	COG1127	ABC transporter
YS110_RS10820	COG1126	abc transporter atp-binding protein
YS110_RS10825	COG0765	amino acid transport
YS110_RS10865	COG3550	peptidyl-serine autophosphorylation
YS110_RS10905	COG4636	protein conserved in cyanobacteria
YS110_RS10915	COG0067	glutamate synthase
YS110_RS10915	COG0069	glutamate synthase activity
YS110_RS10915	COG0070	glutamate synthase
YS110_RS10925	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
YS110_RS10930	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YS110_RS10945	COG0232	Belongs to the dGTPase family. Type 2 subfamily
YS110_RS10950	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
YS110_RS10955	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
YS110_RS10995	COG1965	Belongs to the frataxin family
YS110_RS11015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YS110_RS11020	COG1333	cytochrome c biogenesis protein
YS110_RS11030	COG0218	Necessary for normal cell division and for the maintenance of normal septation
YS110_RS11035	COG0596	Alpha beta hydrolase
YS110_RS11040	COG1560	Kdo2-lipid A biosynthetic process
YS110_RS11050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
YS110_RS11065	COG1216	Glycosyl transferase, family 2
YS110_RS11075	COG1404	Belongs to the peptidase S8 family
YS110_RS11090	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YS110_RS11095	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YS110_RS11120	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS11135	COG0463	Glycosyl transferase, family 2
YS110_RS11145	COG0438	transferase activity, transferring glycosyl groups
YS110_RS11180	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
YS110_RS11185	COG0459	protein refolding
YS110_RS11190	COG4774	siderophore transport
YS110_RS11195	COG0166	Belongs to the GPI family
YS110_RS11205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YS110_RS11215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YS110_RS11220	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
YS110_RS11225	COG0840	transmembrane signaling receptor activity
YS110_RS11230	COG1881	PFAM PEBP family protein
YS110_RS11235	COG4608	Belongs to the ABC transporter superfamily
YS110_RS11240	COG0444	Belongs to the ABC transporter superfamily
YS110_RS11245	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YS110_RS11250	COG1473	amidohydrolase
YS110_RS11270	COG1765	OsmC-like protein
YS110_RS11275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YS110_RS11280	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
YS110_RS11300	COG4970	Tfp pilus assembly protein FimT
YS110_RS11350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YS110_RS11360	COG0004	ammonium transporteR
YS110_RS11375	COG1132	(ABC) transporter
YS110_RS11380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_RS11380	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_RS11385	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_RS11385	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_RS11390	COG3045	CreA protein
YS110_RS11410	COG1566	PFAM secretion protein HlyD family protein
YS110_RS11415	COG2814	Major facilitator Superfamily
YS110_RS11450	COG0488	(ABC) transporter
YS110_RS11460	COG2201	protein-glutamate methylesterase activity
YS110_RS11465	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
YS110_RS11475	COG0835	chemotaxis
YS110_RS11480	COG0643	Histidine kinase
YS110_RS11480	COG2198	Histidine kinase
YS110_RS11485	COG2201	protein-glutamate methylesterase activity
YS110_RS11510	COG1987	bacterial-type flagellum assembly
YS110_RS11535	COG1580	Controls the rotational direction of flagella during chemotaxis
YS110_RS11565	COG1766	The M ring may be actively involved in energy transduction
YS110_RS11570	COG1677	Flagellar hook-basal body complex protein FliE
YS110_RS11605	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YS110_RS11620	COG2089	acid synthase
YS110_RS11625	COG0028	Belongs to the TPP enzyme family
YS110_RS11640	COG0546	phosphoglycolate phosphatase activity
YS110_RS11645	COG0463	Glycosyl transferase, family 2
YS110_RS11645	COG1216	Glycosyl transferase, family 2
YS110_RS11650	COG0438	transferase activity, transferring glycosyl groups
YS110_RS11650	COG1216	Glycosyl transferase, family 2
YS110_RS11665	COG0745	RESPONSE REGULATOR receiver
YS110_RS11670	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YS110_RS11680	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YS110_RS11695	COG1191	sigma factor activity
YS110_RS11715	COG1815	bacterial-type flagellum-dependent cell motility
YS110_RS11720	COG1558	bacterial-type flagellum-dependent cell motility
YS110_RS11725	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YS110_RS11735	COG4787	bacterial-type flagellum-dependent cell motility
YS110_RS11745	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YS110_RS11750	COG0418	dihydroorotase activity
YS110_RS11765	COG0501	Belongs to the peptidase M48B family
YS110_RS11775	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
YS110_RS11795	COG0430	RNA-3'-phosphate cyclase activity
YS110_RS11800	COG1690	Belongs to the RtcB family
YS110_RS11820	COG4650	regulator
YS110_RS11835	COG4269	membrane
YS110_RS11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_RS11855	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
YS110_RS11865	COG1126	abc transporter atp-binding protein
YS110_RS11870	COG0765	amino acid transport
YS110_RS11875	COG0765	amino acid transport
YS110_RS11880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YS110_RS11890	COG0583	DNA-binding transcription factor activity
YS110_RS11900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
YS110_RS11900	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
YS110_RS11905	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YS110_RS11910	COG3706	GGDEF domain
YS110_RS11915	COG5265	(ABC) transporter
YS110_RS11935	COG1024	Enoyl-CoA hydratase
YS110_RS11945	COG0183	Belongs to the thiolase family
YS110_RS11950	COG1024	Enoyl-CoA hydratase
YS110_RS11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_RS11960	COG1960	acyl-CoA dehydrogenase activity
YS110_RS11975	COG1132	(ABC) transporter
YS110_RS11980	COG1309	transcriptional regulator
YS110_RS11990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
YS110_RS12005	COG0204	Acyl-transferase
YS110_RS12005	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS12035	COG0617	tRNA 3'-terminal CCA addition
YS110_RS12040	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YS110_RS12065	COG1116	anion transmembrane transporter activity
YS110_RS12080	COG0203	ribosomal protein L17
YS110_RS12085	COG0202	RNA polymerase activity
YS110_RS12090	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YS110_RS12095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
YS110_RS12100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
YS110_RS12105	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YS110_RS12110	COG0201	protein transport
YS110_RS12115	COG0200	Binds to the 23S rRNA
YS110_RS12120	COG1841	ribosomal large subunit assembly
YS110_RS12125	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
YS110_RS12130	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
YS110_RS12135	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
YS110_RS12140	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
YS110_RS12145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
YS110_RS12150	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
YS110_RS12155	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
YS110_RS12160	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YS110_RS12165	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YS110_RS12180	COG0395	ABC-type sugar transport system, permease component
YS110_RS12190	COG3842	ATPase activity
YS110_RS12195	COG3842	ATPase activity
YS110_RS12205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YS110_RS12215	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YS110_RS12220	COG0783	Belongs to the Dps family
YS110_RS12230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YS110_RS12255	COG2382	esterase
YS110_RS12260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
YS110_RS12265	COG5001	Diguanylate cyclase
YS110_RS12265	COG4251	negative regulation of phosphorylation
YS110_RS12265	COG3706	GGDEF domain
YS110_RS12265	COG2203	Gaf domain
YS110_RS12275	COG2116	formate transmembrane transporter activity
YS110_RS12280	COG3707	response regulator
YS110_RS12290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YS110_RS12295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YS110_RS12310	COG0443	Heat shock 70 kDa protein
YS110_RS12320	COG0443	Heat shock 70 kDa protein
YS110_RS12325	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
YS110_RS12330	COG3300	MHYT domain
YS110_RS12330	COG5001	Diguanylate cyclase
YS110_RS12335	COG0134	indole-3-glycerol-phosphate synthase activity
YS110_RS12345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YS110_RS12350	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
YS110_RS12355	COG0280	phosphate acetyltransferase
YS110_RS12360	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
YS110_RS12370	COG3243	poly(R)-hydroxyalkanoic acid synthase
YS110_RS12375	COG0840	transmembrane signaling receptor activity
YS110_RS12380	COG0045	succinate-CoA ligase (ADP-forming) activity
YS110_RS12380	COG1042	CoA-binding domain protein
YS110_RS12380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YS110_RS12385	COG1131	(ABC) transporter
YS110_RS12390	COG0842	Transport permease protein
YS110_RS12400	COG1250	3-hydroxyacyl-CoA dehydrogenase
YS110_RS12405	COG1846	Transcriptional regulator
YS110_RS12410	COG1764	response to oxidative stress
YS110_RS12420	COG0515	serine threonine protein kinase
YS110_RS12420	COG2815	serine threonine protein kinase
YS110_RS12435	COG2205	protein histidine kinase activity
YS110_RS12490	COG1858	cytochrome C peroxidase
YS110_RS12565	COG2318	DinB family
YS110_RS12570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
YS110_RS12575	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS12590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YS110_RS12595	COG4251	negative regulation of phosphorylation
YS110_RS12595	COG3706	GGDEF domain
YS110_RS12595	COG2203	Gaf domain
YS110_RS12595	COG5001	Diguanylate cyclase
YS110_RS12600	COG0747	negative chemotaxis
YS110_RS12605	COG3012	SEC-C Motif Domain Protein
YS110_RS12705	COG1960	acyl-CoA dehydrogenase activity
YS110_RS12710	COG1366	Belongs to the anti-sigma-factor antagonist family
YS110_RS12720	COG2172	sigma factor antagonist activity
YS110_RS12725	COG0288	reversible hydration of carbon dioxide
YS110_RS12755	COG2208	phosphoserine phosphatase activity
YS110_RS12755	COG2770	Histidine kinase
YS110_RS12770	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YS110_RS12790	COG0183	Belongs to the thiolase family
YS110_RS12795	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
YS110_RS12800	COG0288	reversible hydration of carbon dioxide
YS110_RS12805	COG1960	acyl-CoA dehydrogenase activity
YS110_RS12815	COG0789	Transcriptional regulator
YS110_RS12840	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS12845	COG0183	Belongs to the thiolase family
YS110_RS12850	COG3268	Saccharopine dehydrogenase
YS110_RS12855	COG1960	acyl-CoA dehydrogenase activity
YS110_RS12890	COG0189	ligase activity
YS110_RS12895	COG3135	benzoate transporter
YS110_RS12900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YS110_RS12910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YS110_RS12915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_RS12920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
YS110_RS12930	COG4290	ribonuclease
YS110_RS12935	COG0281	malic enzyme
YS110_RS12935	COG0280	phosphate acetyltransferase
YS110_RS12940	COG3706	GGDEF domain
YS110_RS12985	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS12995	COG1275	C4-dicarboxylate transporter malic acid transport protein
YS110_RS13000	COG1846	Transcriptional regulator
YS110_RS13010	COG1012	belongs to the aldehyde dehydrogenase family
YS110_RS13015	COG4772	TonB-dependent receptor
YS110_RS13030	COG3284	Transcriptional regulator
YS110_RS13080	COG0446	pyridine nucleotide-disulphide oxidoreductase
YS110_RS13100	COG0784	Response regulator, receiver
YS110_RS13100	COG2198	Histidine kinase
YS110_RS13100	COG2205	protein histidine kinase activity
YS110_RS13125	COG0495	leucyl-tRNA aminoacylation
YS110_RS13130	COG0668	transmembrane transport
YS110_RS13140	COG2199	diguanylate cyclase activity
YS110_RS13140	COG2200	EAL domain
YS110_RS13140	COG2202	Pas domain
YS110_RS13150	COG0840	transmembrane signaling receptor activity
YS110_RS13165	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
YS110_RS13170	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YS110_RS13175	COG0735	belongs to the Fur family
YS110_RS13180	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
YS110_RS13190	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YS110_RS13195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
YS110_RS13200	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YS110_RS13205	COG3118	belongs to the thioredoxin family
YS110_RS13210	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YS110_RS13215	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YS110_RS13220	COG0009	L-threonylcarbamoyladenylate synthase
YS110_RS13230	COG3047	cAMP biosynthetic process
YS110_RS13240	COG2027	D-alanyl-D-alanine carboxypeptidase
YS110_RS13245	COG1214	PFAM Peptidase M22, glycoprotease
YS110_RS13250	COG0456	acetyltransferase
YS110_RS13260	COG0598	Magnesium transport protein CorA
YS110_RS13270	COG1132	(ABC) transporter
YS110_RS13280	COG1442	glycosyl transferase family 8
YS110_RS13280	COG1216	Glycosyl transferase, family 2
YS110_RS13285	COG1216	Glycosyl transferase, family 2
YS110_RS13290	COG1215	transferase activity, transferring glycosyl groups
YS110_RS13345	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS13360	COG0469	pyruvate kinase activity
YS110_RS13365	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
YS110_RS13370	COG1690	Belongs to the RtcB family
YS110_RS13375	COG0006	proline dipeptidase activity
YS110_RS13380	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
YS110_RS13385	COG4566	intracellular signal transduction
YS110_RS13415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS13425	COG0745	RESPONSE REGULATOR receiver
YS110_RS13430	COG2205	protein histidine kinase activity
YS110_RS13435	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
YS110_RS13440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YS110_RS13445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YS110_RS13455	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YS110_RS13460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
YS110_RS13470	COG1047	Peptidyl-prolyl cis-trans
YS110_RS13480	COG4774	siderophore transport
YS110_RS13485	COG3712	iron ion homeostasis
YS110_RS13500	COG0840	transmembrane signaling receptor activity
YS110_RS13510	COG0625	glutathione transferase activity
YS110_RS13515	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS13530	COG0840	transmembrane signaling receptor activity
YS110_RS13540	COG2365	Tyrosine phosphatase family
YS110_RS13550	COG1881	PFAM PEBP family protein
YS110_RS13590	COG0642	Histidine kinase
YS110_RS13605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YS110_RS13610	COG2137	regulation of response to DNA damage stimulus
YS110_RS13625	COG0045	succinate-CoA ligase (ADP-forming) activity
YS110_RS13630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YS110_RS13635	COG0631	protein serine/threonine phosphatase activity
YS110_RS13640	COG1716	ATPase activity
YS110_RS13675	COG1216	Glycosyl transferase, family 2
YS110_RS13690	COG0438	transferase activity, transferring glycosyl groups
YS110_RS13700	COG0297	glycogen (starch) synthase activity
YS110_RS13720	COG2755	lipolytic protein G-D-S-L family
YS110_RS13720	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
YS110_RS13735	COG0315	cyclic pyranopterin monophosphate synthase activity
YS110_RS13740	COG4783	chaperone-mediated protein folding
YS110_RS13745	COG1950	PFAM Membrane protein of
YS110_RS13755	COG0861	Integral membrane protein TerC family
YS110_RS13760	COG0861	Integral membrane protein TerC family
YS110_RS13780	COG0625	glutathione transferase activity
YS110_RS13810	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
YS110_RS13830	COG4566	intracellular signal transduction
YS110_RS13855	COG1522	sequence-specific DNA binding
YS110_RS13865	COG1862	Preprotein translocase
YS110_RS13870	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YS110_RS13875	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YS110_RS13885	COG0758	DNA mediated transformation
YS110_RS13890	COG1652	LysM domain
YS110_RS13895	COG0242	peptide deformylase activity
YS110_RS13900	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YS110_RS13915	COG0126	phosphoglycerate kinase activity
YS110_RS13930	COG0284	orotidine-5'-phosphate decarboxylase activity
YS110_RS13940	COG0840	transmembrane signaling receptor activity
YS110_RS13955	COG0456	acetyltransferase
YS110_RS13985	COG2814	Major facilitator Superfamily
YS110_RS13990	COG0629	single-stranded DNA binding
YS110_RS14005	COG0482	sulfurtransferase activity
YS110_RS14030	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
YS110_RS14045	COG0642	Histidine kinase
YS110_RS14080	COG0277	FAD linked oxidase domain protein
YS110_RS14090	COG2096	Adenosyltransferase
YS110_RS14095	COG2050	protein possibly involved in aromatic compounds catabolism
YS110_RS14110	COG2233	PERMEase
YS110_RS14140	COG0501	Belongs to the peptidase M48B family
YS110_RS14150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
YS110_RS14155	COG1183	phosphatidylcholine synthase activity
YS110_RS14160	COG4774	siderophore transport
YS110_RS14180	COG0850	regulation of cytokinetic process
YS110_RS14190	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YS110_RS14205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YS110_RS14235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS14240	COG1129	ABC transporter
YS110_RS14240	COG0842	Transport permease protein
YS110_RS14245	COG0842	Transport permease protein
YS110_RS14250	COG3586	endonuclease activity
YS110_RS14265	COG1254	Belongs to the acylphosphatase family
YS110_RS14290	COG0745	RESPONSE REGULATOR receiver
YS110_RS14300	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YS110_RS14310	COG0840	transmembrane signaling receptor activity
YS110_RS14320	COG1199	ATP-dependent helicase activity
YS110_RS14325	COG0840	transmembrane signaling receptor activity
YS110_RS14330	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YS110_RS14335	COG2824	Alkylphosphonate utilization operon protein PhnA
YS110_RS14345	COG2258	MOSC domain
YS110_RS14350	COG2189	Belongs to the N(4) N(6)-methyltransferase family
YS110_RS14365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_RS14370	COG0791	NLP P60 protein
YS110_RS14375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YS110_RS14390	COG2974	May be involved in recombination
YS110_RS14395	COG0700	Nucleoside recognition
YS110_RS14405	COG1960	acyl-CoA dehydrogenase activity
YS110_RS14410	COG0183	Belongs to the thiolase family
YS110_RS14415	COG1024	Enoyl-CoA hydratase
YS110_RS14470	COG0789	Transcriptional regulator
YS110_RS14480	COG2217	Heavy metal translocating P-type atpase
YS110_RS14485	COG0840	transmembrane signaling receptor activity
YS110_RS14505	COG0745	RESPONSE REGULATOR receiver
YS110_RS14515	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YS110_RS14525	COG1902	pentaerythritol trinitrate reductase activity
YS110_RS14530	COG0625	glutathione transferase activity
YS110_RS14560	COG0445	tRNA wobble uridine modification
YS110_RS14565	COG0357	Ribosomal RNA small subunit methyltransferase G
YS110_RS14575	COG1192	Involved in chromosome partitioning
YS110_RS14650	COG1309	transcriptional regulator
YS110_RS14655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS14665	COG0577	efflux transmembrane transporter activity
YS110_RS14665	COG1136	(ABC) transporter
YS110_RS14695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YS110_RS14700	COG2267	carboxylic ester hydrolase activity
YS110_RS14710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
YS110_RS14720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YS110_RS14730	COG3158	transport of potassium into the cell
YS110_RS14740	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
YS110_RS14755	COG3154	lipid carrier protein
YS110_RS14760	COG0826	peptidase U32
YS110_RS14765	COG0826	peptidase U32
YS110_RS14770	COG2814	Major facilitator Superfamily
YS110_RS14785	COG2267	carboxylic ester hydrolase activity
YS110_RS14795	COG0840	transmembrane signaling receptor activity
YS110_RS14805	COG0840	transmembrane signaling receptor activity
YS110_RS14810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_RS14815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
YS110_RS14820	COG2119	membrane
YS110_RS14825	COG0724	RNA recognition motif
YS110_RS14830	COG0724	RNA recognition motif
YS110_RS14895	COG5489	Protein of unknown function (DUF736)
YS110_RS14925	COG1192	Involved in chromosome partitioning
YS110_RS14940	COG4959	Type IV secretory pathway protease TraF
YS110_RS14950	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
YS110_RS14955	COG1877	trehalose-phosphatase activity
YS110_RS14960	COG0745	RESPONSE REGULATOR receiver
YS110_RS14965	COG2205	protein histidine kinase activity
YS110_RS14970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YS110_RS14975	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
YS110_RS14985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
YS110_RS15010	COG0583	DNA-binding transcription factor activity
YS110_RS15030	COG4962	Type ii secretion system protein e
YS110_RS15035	COG3838	Conjugal transfer protein Trbc
YS110_RS15045	COG3451	type IV secretory pathway VirB4
YS110_RS15085	COG0300	oxidoreductase activity
YS110_RS15095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YS110_RS15100	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YS110_RS15100	COG0517	IMP dehydrogenase activity
YS110_RS15115	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YS110_RS15150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
YS110_RS15155	COG0747	negative chemotaxis
YS110_RS15160	COG0706	membrane insertase activity
YS110_RS15165	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
YS110_RS15170	COG0594	ribonuclease P activity
YS110_RS15175	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YS110_RS15180	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YS110_RS15195	COG2249	NAD(P)H dehydrogenase (quinone) activity
YS110_RS15240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
YS110_RS15250	COG0786	glutamate:sodium symporter activity
YS110_RS15255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS15320	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
YS110_RS15330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YS110_RS15345	COG3712	iron ion homeostasis
YS110_RS15350	COG1595	DNA-templated transcription, initiation
YS110_RS15365	COG1595	DNA-templated transcription, initiation
YS110_RS15370	COG4774	siderophore transport
YS110_RS15375	COG3712	iron ion homeostasis
YS110_RS15380	COG1595	DNA-templated transcription, initiation
YS110_RS15390	COG3712	iron ion homeostasis
YS110_RS15395	COG1595	DNA-templated transcription, initiation
YS110_RS15405	COG1960	acyl-CoA dehydrogenase activity
YS110_RS15415	COG3604	Transcriptional regulator
YS110_RS15445	COG4636	protein conserved in cyanobacteria
YS110_RS15470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
YS110_RS15495	COG4771	TonB-dependent receptor
YS110_RS15515	COG0348	domain, Protein
YS110_RS15520	COG0723	plastoquinol--plastocyanin reductase activity
YS110_RS15525	COG2204	response regulator
YS110_RS15540	COG0784	Response regulator, receiver
YS110_RS15540	COG2198	Histidine kinase
YS110_RS15540	COG2205	protein histidine kinase activity
YS110_RS15580	COG1410	methionine synthase
YS110_RS15580	COG0646	methionine synthase
YS110_RS15590	COG4771	TonB-dependent receptor
YS110_RS15600	COG1070	Carbohydrate kinase
YS110_RS15605	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YS110_RS15610	COG0277	FAD linked oxidase domain protein
YS110_RS15630	COG0598	Magnesium transport protein CorA
YS110_RS15640	COG1981	membrane
YS110_RS15655	COG2945	thiolester hydrolase activity
YS110_RS15660	COG1686	Belongs to the peptidase S11 family
YS110_RS15665	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YS110_RS15670	COG0049	tRNA binding
YS110_RS15675	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
YS110_RS15680	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
YS110_RS15685	COG0051	transcription antitermination factor activity, RNA binding
YS110_RS15690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
YS110_RS15695	COG0088	Forms part of the polypeptide exit tunnel
YS110_RS15700	COG0089	rRNA binding
YS110_RS15705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
YS110_RS15710	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YS110_RS15715	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
YS110_RS15720	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YS110_RS15725	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YS110_RS15730	COG0255	Belongs to the universal ribosomal protein uL29 family
YS110_RS15735	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YS110_RS15740	COG0678	peroxiredoxin activity
YS110_RS15770	COG3909	cytochrome
YS110_RS15775	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_RS15785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YS110_RS15790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YS110_RS15855	COG0583	DNA-binding transcription factor activity
YS110_RS15860	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS15865	COG5002	protein histidine kinase activity
YS110_RS15865	COG3850	Histidine kinase
YS110_RS15890	COG3239	Fatty acid desaturase
YS110_RS15900	COG2207	Transcriptional regulator
YS110_RS15910	COG0347	Belongs to the P(II) protein family
YS110_RS15915	COG0004	ammonium transporteR
YS110_RS15920	COG5001	Diguanylate cyclase
YS110_RS15920	COG2203	Gaf domain
YS110_RS15920	COG3706	GGDEF domain
YS110_RS15920	COG4251	negative regulation of phosphorylation
YS110_RS15925	COG0277	FAD linked oxidase domain protein
YS110_RS15935	COG0247	lactate metabolic process
YS110_RS15940	COG3300	MHYT domain
YS110_RS15940	COG5001	Diguanylate cyclase
YS110_RS15965	COG0386	Belongs to the glutathione peroxidase family
YS110_RS15975	COG0477	Major facilitator Superfamily
YS110_RS15980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YS110_RS15985	COG1858	cytochrome C peroxidase
YS110_RS15995	COG0672	)-iron permease
YS110_RS16020	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
YS110_RS16025	COG0765	amino acid transport
YS110_RS16030	COG0765	amino acid transport
YS110_RS16035	COG4771	TonB-dependent receptor
YS110_RS16045	COG4174	ABC transporter (Permease)
YS110_RS16050	COG4239	(ABC) transporter, permease
YS110_RS16055	COG4172	Belongs to the ABC transporter superfamily
YS110_RS16060	COG4166	transmembrane transport
YS110_RS16065	COG1132	(ABC) transporter
YS110_RS16070	COG1132	(ABC) transporter
YS110_RS16145	COG0477	Major facilitator Superfamily
YS110_RS16195	COG0745	RESPONSE REGULATOR receiver
YS110_RS16200	COG2211	Major facilitator Superfamily
YS110_RS16220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS16225	COG0577	efflux transmembrane transporter activity
YS110_RS16225	COG1136	(ABC) transporter
YS110_RS16230	COG1538	Outer membrane efflux protein
YS110_RS16340	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS16345	COG4569	acetaldehyde dehydrogenase (acetylating) activity
YS110_RS16350	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
YS110_RS16385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS16415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YS110_RS16420	COG1309	transcriptional regulator
YS110_RS16435	COG0179	Fumarylacetoacetate (FAA) hydrolase
YS110_RS16445	COG0604	alcohol dehydrogenase
YS110_RS16450	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS16455	COG0457	Tetratricopeptide repeat
YS110_RS16455	COG0463	Glycosyl transferase, family 2
YS110_RS16470	COG0708	Exodeoxyribonuclease III
YS110_RS16475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
YS110_RS16490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YS110_RS16495	COG1192	Involved in chromosome partitioning
YS110_RS16505	COG0154	amidase activity
YS110_RS16510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
YS110_RS16515	COG1077	Cell shape determining protein MreB Mrl
YS110_RS16530	COG0768	penicillin binding
YS110_RS16545	COG0004	ammonium transporteR
YS110_RS16560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YS110_RS16565	COG1127	ABC transporter
YS110_RS16580	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
YS110_RS16585	COG0321	lipoyl(octanoyl) transferase activity
YS110_RS16590	COG2921	Belongs to the UPF0250 family
YS110_RS16600	COG0356	it plays a direct role in the translocation of protons across the membrane
YS110_RS16610	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
YS110_RS16615	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
YS110_RS16620	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
YS110_RS16625	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
YS110_RS16630	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
YS110_RS16635	COG0355	proton-transporting ATP synthase activity, rotational mechanism
YS110_RS16645	COG3245	cytochrome
YS110_RS16655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YS110_RS16660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS16700	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YS110_RS16710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
YS110_RS16715	COG0081	regulation of translation
YS110_RS16720	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
YS110_RS16725	COG0222	ribosome binding
YS110_RS16730	COG0085	RNA polymerase activity
YS110_RS16735	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
YS110_RS16745	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YS110_RS16745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_RS16755	COG5000	phosphorelay sensor kinase activity
YS110_RS16760	COG2204	response regulator
YS110_RS16770	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YS110_RS16775	COG0792	nuclease activity
YS110_RS16780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
YS110_RS16785	COG2823	Periplasmic or secreted lipoprotein
YS110_RS16790	COG2084	Dehydrogenase
YS110_RS16800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS16810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YS110_RS16820	COG0577	efflux transmembrane transporter activity
YS110_RS16820	COG1136	(ABC) transporter
YS110_RS16825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS16830	COG1309	transcriptional regulator
YS110_RS16840	COG4770	biotin carboxylase activity
YS110_RS16850	COG5001	Diguanylate cyclase
YS110_RS16865	COG1116	anion transmembrane transporter activity
YS110_RS16865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_RS16890	COG0583	DNA-binding transcription factor activity
YS110_RS16895	COG0277	FAD linked oxidase domain protein
YS110_RS16915	COG2909	trisaccharide binding
YS110_RS16925	COG0683	leucine binding
YS110_RS16940	COG0411	ABC transporter
YS110_RS16950	COG0277	FAD linked oxidase domain protein
YS110_RS16955	COG4585	Histidine kinase
YS110_RS16960	COG2197	response regulator
YS110_RS16970	COG2223	nitrite transmembrane transporter activity
YS110_RS16975	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
YS110_RS16980	COG1140	nitrate reductase beta subunit
YS110_RS16985	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
YS110_RS16990	COG2181	nitrate reductase activity
YS110_RS17000	COG0288	reversible hydration of carbon dioxide
YS110_RS17035	COG3945	hemerythrin HHE cation binding domain
YS110_RS17060	COG1979	alcohol dehydrogenase
YS110_RS17065	COG1472	Belongs to the glycosyl hydrolase 3 family
YS110_RS17070	COG0243	molybdopterin cofactor binding
YS110_RS17075	COG1473	amidohydrolase
YS110_RS17155	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YS110_RS17165	COG0326	Molecular chaperone. Has ATPase activity
YS110_RS17190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YS110_RS17200	COG1942	4-Oxalocrotonate Tautomerase
YS110_RS17205	COG2814	Major facilitator Superfamily
YS110_RS17210	COG0121	glutamine amidotransferase
YS110_RS17215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS17225	COG2186	Transcriptional regulator
YS110_RS17230	COG1304	FMN binding
YS110_RS17235	COG0277	FAD linked oxidase domain protein
YS110_RS17240	COG4191	Histidine kinase
YS110_RS17245	COG1301	dicarboxylic acid transport
YS110_RS17265	COG3712	iron ion homeostasis
YS110_RS17270	COG1595	DNA-templated transcription, initiation
YS110_RS17285	COG0018	arginyl-trna synthetase
YS110_RS17295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YS110_RS17305	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_RS17315	COG1137	ATPase activity
YS110_RS17320	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YS110_RS17330	COG0840	transmembrane signaling receptor activity
YS110_RS17345	COG0653	protein targeting
YS110_RS17355	COG0745	RESPONSE REGULATOR receiver
YS110_RS17365	COG0840	transmembrane signaling receptor activity
YS110_RS17370	COG1546	Belongs to the CinA family
YS110_RS17375	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YS110_RS17390	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
YS110_RS17435	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
YS110_RS17450	COG2967	ApaG domain
YS110_RS17455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YS110_RS17465	COG0546	phosphoglycolate phosphatase activity
YS110_RS17475	COG0840	transmembrane signaling receptor activity
YS110_RS17505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YS110_RS17520	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
YS110_RS17525	COG1490	D-aminoacyl-tRNA deacylase activity
YS110_RS17530	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_RS17540	COG0477	Major facilitator Superfamily
YS110_RS17555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YS110_RS17565	COG0038	chloride channel
YS110_RS17570	COG2814	Major facilitator Superfamily
YS110_RS17575	COG0583	DNA-binding transcription factor activity
YS110_RS17585	COG2423	ornithine cyclodeaminase activity
YS110_RS17590	COG2010	Cytochrome c
YS110_RS17600	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
YS110_RS17610	COG4774	siderophore transport
YS110_RS17635	COG4804	nuclease activity
YS110_RS17670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
YS110_RS17690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YS110_RS17695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YS110_RS17705	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
YS110_RS17710	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
YS110_RS17715	COG0316	Belongs to the HesB IscA family
YS110_RS17720	COG2814	Major facilitator Superfamily
YS110_RS17725	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
YS110_RS17730	COG0739	heme binding
YS110_RS17735	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
YS110_RS17740	COG2703	oxygen carrier activity
YS110_RS17745	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
YS110_RS17765	COG1522	sequence-specific DNA binding
YS110_RS17850	COG4372	Transposase
YS110_RS17955	COG1196	nuclear chromosome segregation
YS110_RS17980	COG2814	Major facilitator Superfamily
YS110_RS17985	COG2814	Major facilitator Superfamily
YS110_RS17995	COG0583	DNA-binding transcription factor activity
YS110_RS18015	COG3616	Alanine racemase, N-terminal domain
YS110_RS18030	COG0037	tRNA processing
YS110_RS18060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
YS110_RS18080	COG0625	glutathione transferase activity
YS110_RS18085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YS110_RS18110	COG3128	pkhd-type hydroxylase
YS110_RS18120	COG4774	siderophore transport
YS110_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS18155	COG3186	Phenylalanine-4-hydroxylase
YS110_RS18170	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
YS110_RS18175	COG1522	sequence-specific DNA binding
YS110_RS18190	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YS110_RS18195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YS110_RS18205	COG0752	glycyl-tRNA synthetase alpha subunit
YS110_RS18210	COG0751	glycine-tRNA ligase activity
YS110_RS18215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YS110_RS18240	COG1122	ATPase activity
YS110_RS18250	COG1268	BioY protein
YS110_RS18255	COG0318	PFAM AMP-dependent synthetase and ligase
YS110_RS18315	COG2255	four-way junction helicase activity
YS110_RS18320	COG0632	four-way junction helicase activity
YS110_RS18325	COG1702	phosphate starvation-inducible protein PhoH
YS110_RS18330	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
YS110_RS18335	COG0730	response to heat
YS110_RS18345	COG1652	LysM domain
YS110_RS18350	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
YS110_RS18370	COG4221	oxidoreductase activity
YS110_RS18395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YS110_RS18400	COG1459	type II secretion system
YS110_RS18405	COG2165	general secretion pathway protein
YS110_RS18415	COG2165	general secretion pathway protein
YS110_RS18445	COG1450	Type ii and iii secretion system protein
YS110_RS18470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YS110_RS18490	COG1216	Glycosyl transferase, family 2
YS110_RS18515	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
YS110_RS18520	COG0343	queuine tRNA-ribosyltransferase activity
YS110_RS18525	COG0589	response to stress
YS110_RS18540	COG0210	DNA helicase
YS110_RS18545	COG0679	Auxin Efflux Carrier
YS110_RS18555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YS110_RS18560	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
YS110_RS18570	COG3237	CsbD-like
YS110_RS18580	COG1832	CoA-binding protein
YS110_RS18600	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YS110_RS18605	COG4232	protein-disulfide reductase activity
YS110_RS18645	COG3048	D-serine ammonia-lyase activity
YS110_RS18650	COG0384	phenazine biosynthesis protein PhzF
YS110_RS18655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS18660	COG0697	spore germination
YS110_RS18670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS18690	COG3951	Flagellar rod assembly protein muramidase FlgJ
YS110_RS18690	COG1705	Flagellar rod assembly protein muramidase FlgJ
YS110_RS18695	COG1706	bacterial-type flagellum-dependent cell motility
YS110_RS18700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YS110_RS18710	COG0523	cobalamin synthesis protein
YS110_RS18725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
YS110_RS18730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
YS110_RS18735	COG3829	transcription factor binding
YS110_RS18790	COG1172	Belongs to the binding-protein-dependent transport system permease family
YS110_RS18830	COG2001	Belongs to the MraZ family
YS110_RS18835	COG0275	rRNA processing
YS110_RS18840	COG3116	cell division
YS110_RS18850	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YS110_RS18855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YS110_RS18860	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YS110_RS18865	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
YS110_RS18870	COG0772	Belongs to the SEDS family
YS110_RS18875	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
YS110_RS18880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YS110_RS18885	COG1181	Belongs to the D-alanine--D-alanine ligase family
YS110_RS18890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YS110_RS18900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YS110_RS18905	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
YS110_RS18915	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YS110_RS18925	COG0840	transmembrane signaling receptor activity
YS110_RS18945	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
YS110_RS18950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YS110_RS18955	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YS110_RS18965	COG0557	exoribonuclease II activity
YS110_RS18975	COG3150	esterase
YS110_RS18980	COG0772	Belongs to the SEDS family
YS110_RS18985	COG0312	modulator of DNA gyrase
YS110_RS18995	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YS110_RS19005	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YS110_RS19015	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_RS19020	COG0511	ligase activity, forming carbon-carbon bonds
YS110_RS19025	COG0439	Biotin carboxylase
YS110_RS19030	COG2264	protein methyltransferase activity
YS110_RS19040	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YS110_RS19060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YS110_RS19060	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
YS110_RS19085	COG4137	Cytochrome C assembly protein
YS110_RS19090	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YS110_RS19095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YS110_RS19100	COG4804	nuclease activity
YS110_RS19110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
YS110_RS19120	COG1024	Enoyl-CoA hydratase
YS110_RS19140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YS110_RS19145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YS110_RS19150	COG0012	GTP binding
YS110_RS19165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YS110_RS19170	COG1758	RNA polymerase activity
YS110_RS19175	COG0194	GDP metabolic process
YS110_RS19180	COG1561	YicC-like family, N-terminal region
YS110_RS19200	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YS110_RS19205	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YS110_RS19240	COG3622	Belongs to the hyi family
YS110_RS19250	COG2186	Transcriptional regulator
YS110_RS19265	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
YS110_RS19275	COG0840	transmembrane signaling receptor activity
YS110_RS19280	COG2233	PERMEase
YS110_RS19310	COG1120	ATPase activity
YS110_RS19315	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS19390	COG0281	malic enzyme
YS110_RS19390	COG0280	phosphate acetyltransferase
YS110_RS19400	COG1116	anion transmembrane transporter activity
YS110_RS19405	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_RS19410	COG2814	Major facilitator Superfamily
YS110_RS19415	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
YS110_RS19420	COG0159	tryptophan synthase activity
YS110_RS19425	COG0133	tryptophan synthase activity
YS110_RS19430	COG0135	phosphoribosylanthranilate isomerase activity
YS110_RS19435	COG0101	tRNA pseudouridine synthase activity
YS110_RS19455	COG0473	3-isopropylmalate dehydrogenase activity
YS110_RS19460	COG0066	3-isopropylmalate dehydratase activity
YS110_RS19465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
YS110_RS19475	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YS110_RS19480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
YS110_RS19485	COG0492	ferredoxin-NADP+ reductase activity
YS110_RS19495	COG1674	ftsk spoiiie
YS110_RS19510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
YS110_RS19550	COG0604	alcohol dehydrogenase
YS110_RS19555	COG1309	transcriptional regulator
YS110_RS19565	COG1573	uracil-dna glycosylase
YS110_RS19645	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YS110_RS19675	COG1392	Phosphate transport regulator
YS110_RS19680	COG0306	phosphate transporter
YS110_RS19695	COG0228	four-way junction DNA binding
YS110_RS19700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
YS110_RS19705	COG0336	Belongs to the RNA methyltransferase TrmD family
YS110_RS19710	COG0335	large ribosomal subunit rRNA binding
YS110_RS19715	COG0494	nUDIX hydrolase
YS110_RS19720	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
YS110_RS19725	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
YS110_RS19735	COG0659	secondary active sulfate transmembrane transporter activity
YS110_RS19740	COG1162	GTPase activity
YS110_RS19745	COG2154	pterin-4-alpha-carbinolamine dehydratase
YS110_RS19750	COG0501	Belongs to the peptidase M48B family
YS110_RS19755	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YS110_RS19765	COG0513	Belongs to the DEAD box helicase family
YS110_RS19770	COG3300	MHYT domain
YS110_RS19770	COG5001	Diguanylate cyclase
YS110_RS19775	COG2814	Major facilitator Superfamily
YS110_RS19785	COG2084	Dehydrogenase
YS110_RS19795	COG0516	GMP reductase activity
YS110_RS19800	COG0210	DNA helicase
YS110_RS19810	COG1785	Belongs to the alkaline phosphatase family
YS110_RS19815	COG1785	Belongs to the alkaline phosphatase family
YS110_RS19830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YS110_RS19855	COG0412	Dienelactone hydrolase
YS110_RS19870	COG4771	TonB-dependent receptor
YS110_RS19875	COG0500	methyltransferase
YS110_RS19890	COG3275	phosphorelay sensor kinase activity
YS110_RS19895	COG0165	Argininosuccinate lyase
YS110_RS19900	COG2015	COG2015, Alkyl sulfatase and related hydrolases
YS110_RS19925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
YS110_RS19930	COG0484	heat shock protein binding
YS110_RS19935	COG0443	Heat shock 70 kDa protein
YS110_RS19940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
YS110_RS19945	COG0360	Binds together with S18 to 16S ribosomal RNA
YS110_RS19955	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YS110_RS19960	COG0359	binds to the 23S rRNA
YS110_RS19975	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
YS110_RS19980	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YS110_RS20010	COG0697	spore germination
YS110_RS20025	COG0583	DNA-binding transcription factor activity
YS110_RS20035	COG1283	sodium-dependent phosphate transmembrane transporter activity
YS110_RS20050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
YS110_RS20055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
YS110_RS20060	COG0196	riboflavin kinase activity
YS110_RS20070	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YS110_RS20095	COG1960	acyl-CoA dehydrogenase activity
YS110_RS20100	COG1960	acyl-CoA dehydrogenase activity
YS110_RS20105	COG3132	Protein of unknown function, DUF480
YS110_RS20110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YS110_RS20140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
YS110_RS20140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
YS110_RS20150	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YS110_RS20180	COG1160	GTP binding
YS110_RS20245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YS110_RS20260	COG2199	diguanylate cyclase activity
YS110_RS20270	COG1304	FMN binding
YS110_RS20275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
YS110_RS20285	COG0840	transmembrane signaling receptor activity
YS110_RS20290	COG0840	transmembrane signaling receptor activity
YS110_RS20305	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YS110_RS20305	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
YS110_RS20310	COG1297	OPT oligopeptide transporter protein
YS110_RS20320	COG3022	response to hydroperoxide
YS110_RS20325	COG1530	ribonuclease E activity
YS110_RS20330	COG0564	pseudouridine synthase activity
YS110_RS20345	COG0616	signal peptide processing
YS110_RS20345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
YS110_RS20355	COG0424	maF-like protein
YS110_RS20360	COG1399	metal-binding, possibly nucleic acid-binding protein
YS110_RS20365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YS110_RS20370	COG0416	fatty acid biosynthetic process
YS110_RS20375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YS110_RS20380	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YS110_RS20385	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS20390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YS110_RS20395	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YS110_RS20410	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YS110_RS20415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YS110_RS20420	COG2205	protein histidine kinase activity
YS110_RS20425	COG0745	RESPONSE REGULATOR receiver
YS110_RS20445	COG0481	GTPase activity
YS110_RS20450	COG0681	Belongs to the peptidase S26 family
YS110_RS20460	COG0571	ribonuclease III activity
YS110_RS20465	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
YS110_RS20470	COG1381	Involved in DNA repair and RecF pathway recombination
YS110_RS20475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YS110_RS20480	COG0736	holo-[acyl-carrier-protein] synthase activity
YS110_RS20515	COG2132	Multicopper oxidase
YS110_RS20550	COG3706	GGDEF domain
YS110_RS20550	COG2203	Gaf domain
YS110_RS20550	COG5001	Diguanylate cyclase
YS110_RS20550	COG4251	negative regulation of phosphorylation
YS110_RS20555	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
YS110_RS20575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
YS110_RS20590	COG0762	integral membrane protein
YS110_RS20620	COG3706	GGDEF domain
YS110_RS20640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
YS110_RS20650	COG3845	ABC transporter
YS110_RS20655	COG4603	Belongs to the binding-protein-dependent transport system permease family
YS110_RS20675	COG2366	antibiotic biosynthetic process
YS110_RS20680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
YS110_RS20690	COG0537	adenosine 5'-monophosphoramidase activity
YS110_RS20695	COG0402	S-adenosylhomocysteine deaminase activity
YS110_RS20700	COG0717	Belongs to the dCTP deaminase family
YS110_RS20705	COG2423	ornithine cyclodeaminase activity
YS110_RS20710	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
YS110_RS20715	COG2321	neutral zinc metallopeptidase
YS110_RS20720	COG0513	Belongs to the DEAD box helicase family
YS110_RS20780	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
YS110_RS20795	COG0348	domain, Protein
YS110_RS20795	COG3901	Regulator of nitric oxide reductase transcription
YS110_RS20800	COG4263	nitrous-oxide reductase activity
YS110_RS20825	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
YS110_RS20830	COG1253	flavin adenine dinucleotide binding
YS110_RS20835	COG2916	Histone family protein nucleoid-structuring protein H-NS
YS110_RS20840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YS110_RS20845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YS110_RS20865	COG0727	PFAM Uncharacterised protein family (UPF0153)
YS110_RS20875	COG1918	ferrous iron import across plasma membrane
YS110_RS20875	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
YS110_RS20890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YS110_RS20895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
YS110_RS20905	COG0268	Binds directly to 16S ribosomal RNA
YS110_RS20910	COG0728	peptidoglycan biosynthetic process
YS110_RS20920	COG0589	response to stress
YS110_RS20940	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
YS110_RS20945	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
YS110_RS20955	COG0617	tRNA 3'-terminal CCA addition
YS110_RS20960	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YS110_RS20965	COG0463	Glycosyl transferase, family 2
YS110_RS20970	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YS110_RS21005	COG0483	inositol monophosphate 1-phosphatase activity
YS110_RS21020	COG1045	serine acetyltransferase
YS110_RS21030	COG1063	alcohol dehydrogenase
YS110_RS21040	COG0521	Mo-molybdopterin cofactor biosynthetic process
YS110_RS21045	COG3028	Belongs to the UPF0307 family
YS110_RS21050	COG0312	modulator of DNA gyrase
YS110_RS21060	COG1752	Esterase of the alpha-beta hydrolase superfamily
YS110_RS21065	COG4106	trans-aconitate 2-methyltransferase activity
YS110_RS21070	COG0473	3-isopropylmalate dehydrogenase activity
YS110_RS21090	COG0828	Belongs to the bacterial ribosomal protein bS21 family
YS110_RS21100	COG2081	HI0933 family
YS110_RS21110	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
YS110_RS21110	COG1648	precorrin-2 dehydrogenase activity
YS110_RS21115	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YS110_RS21120	COG1116	anion transmembrane transporter activity
YS110_RS21125	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YS110_RS21130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YS110_RS21135	COG0243	molybdopterin cofactor binding
YS110_RS21140	COG0840	transmembrane signaling receptor activity
YS110_RS21145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YS110_RS21145	COG0517	IMP dehydrogenase activity
YS110_RS21150	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
YS110_RS21160	COG0683	leucine binding
YS110_RS21170	COG0583	DNA-binding transcription factor activity
YS110_RS21180	COG1136	(ABC) transporter
YS110_RS21210	COG1595	DNA-templated transcription, initiation
YS110_RS21215	COG2951	lytic endotransglycosylase activity
YS110_RS21230	COG0714	Associated with various cellular activities
YS110_RS21240	COG1024	Enoyl-CoA hydratase
YS110_RS21245	COG1196	nuclear chromosome segregation
YS110_RS21245	COG3264	Mechanosensitive ion channel
YS110_RS21260	COG1960	acyl-CoA dehydrogenase activity
YS110_RS21275	COG2223	nitrite transmembrane transporter activity
YS110_RS21280	COG3228	Belongs to the MtfA family
YS110_RS21285	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YS110_RS21310	COG0215	cysteine-tRNA ligase activity
YS110_RS21325	COG0037	tRNA processing
YS110_RS21345	COG2910	NAD(P)H-binding
YS110_RS21355	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YS110_RS21360	COG2204	response regulator
YS110_RS21400	COG1067	ATP-dependent peptidase activity
YS110_RS21405	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
YS110_RS21425	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
YS110_RS21430	COG1562	ergosterol biosynthetic process
YS110_RS21440	COG1132	(ABC) transporter
YS110_RS21440	COG2375	cellular response to nickel ion
YS110_RS21445	COG1132	(ABC) transporter
YS110_RS21450	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS21455	COG4605	iron ion homeostasis
YS110_RS21460	COG4604	ABC transporter, ATP-binding protein
YS110_RS21465	COG4607	ABC-type enterochelin transport system periplasmic component
YS110_RS21470	COG4774	siderophore transport
YS110_RS21475	COG2375	cellular response to nickel ion
YS110_RS21485	COG1760	l-serine dehydratase
YS110_RS21495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YS110_RS21510	COG0544	peptidyl-prolyl cis-trans isomerase activity
YS110_RS21515	COG0740	serine-type endopeptidase activity
YS110_RS21520	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
YS110_RS21525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YS110_RS21550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_RS21565	COG1451	nucleotide metabolic process
YS110_RS21570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
YS110_RS21600	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
YS110_RS21620	COG0400	carboxylic ester hydrolase activity
YS110_RS21625	COG1228	amidohydrolase
YS110_RS21630	COG0668	transmembrane transport
YS110_RS21645	COG3634	alkyl hydroperoxide reductase activity
YS110_RS21670	COG3654	unkown
YS110_RS21705	COG2204	response regulator
YS110_RS21710	COG4191	Histidine kinase
YS110_RS21715	COG2326	polyphosphate kinase activity
YS110_RS21725	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YS110_RS21730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YS110_RS21735	COG4558	Periplasmic binding protein
YS110_RS21750	COG4206	TonB-dependent receptor
YS110_RS21800	COG0798	PFAM Bile acid sodium symporter
YS110_RS21810	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
YS110_RS21825	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YS110_RS21845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
YS110_RS21870	COG1595	DNA-templated transcription, initiation
YS110_RS21890	COG1477	protein flavinylation
YS110_RS21895	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
YS110_RS21900	COG4771	TonB-dependent receptor
YS110_RS21905	COG0789	Transcriptional regulator
YS110_RS21925	COG2818	Glycosylase
YS110_RS21935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YS110_RS21940	COG0358	DNA primase activity
YS110_RS21995	COG3321	synthase
YS110_RS21995	COG1028	Short-chain dehydrogenase reductase Sdr
YS110_RS21995	COG0604	alcohol dehydrogenase
YS110_RS22000	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
YS110_RS22005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
YS110_RS22015	COG0564	pseudouridine synthase activity
YS110_RS22025	COG1187	pseudouridine synthase activity
YS110_RS22030	COG0105	UTP biosynthetic process
YS110_RS22035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
YS110_RS22050	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
YS110_RS22055	COG0124	histidyl-tRNA synthetase
YS110_RS22065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YS110_RS22070	COG1160	GTP binding
YS110_RS22075	COG1923	regulation of RNA biosynthetic process
YS110_RS22080	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YS110_RS22085	COG0330	HflC and HflK could
YS110_RS22090	COG0330	HflC and HflK could
YS110_RS22100	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
YS110_RS22105	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
YS110_RS22170	COG0174	glutamine synthetase
YS110_RS22180	COG3852	Histidine kinase
YS110_RS22185	COG2204	response regulator
YS110_RS22190	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
YS110_RS22195	COG0708	Exodeoxyribonuclease III
YS110_RS22220	COG0840	transmembrane signaling receptor activity
YS110_RS22225	COG0840	transmembrane signaling receptor activity
YS110_RS22245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YS110_RS22250	COG2194	sulfuric ester hydrolase activity
YS110_RS22280	COG0039	L-malate dehydrogenase activity
YS110_RS22285	COG2188	Transcriptional regulator
YS110_RS22300	COG1053	succinate dehydrogenase
YS110_RS22305	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YS110_RS22310	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YS110_RS22315	COG0372	Belongs to the citrate synthase family
YS110_RS22325	COG2197	response regulator
YS110_RS22340	COG3916	Acyl-homoserine-lactone synthase
YS110_RS22370	COG3209	COG3209 Rhs family protein
YS110_RS22395	COG3191	aminopeptidase activity
YS110_RS22425	COG0789	Transcriptional regulator
YS110_RS22460	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YS110_RS22465	COG0573	inorganic phosphate transmembrane transporter activity
YS110_RS22470	COG0581	inorganic phosphate transmembrane transporter activity
YS110_RS22475	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
YS110_RS22480	COG0704	Plays a role in the regulation of phosphate uptake
YS110_RS22500	COG3504	Conjugal transfer protein
YS110_RS22505	COG2948	multi-organism process
YS110_RS22515	COG1192	Involved in chromosome partitioning
YS110_RS22520	COG1475	DNA binding
YS110_RS22635	COG1525	nuclease
YS110_RS22720	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YS110_RS22775	COG4962	Type ii secretion system protein e
YS110_RS22780	COG3838	Conjugal transfer protein Trbc
YS110_RS22785	COG5268	conjugation
YS110_RS22790	COG3451	type IV secretory pathway VirB4
YS110_RS22810	COG3701	Conjugal transfer protein
YS110_RS22835	COG0840	transmembrane signaling receptor activity