locus-tag	class	description
ABOO_RS00015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ABOO_RS00020	COG0010	Belongs to the arginase family
ABOO_RS00065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABOO_RS00110	COG1033	growth of symbiont in host cell
ABOO_RS00110	COG2409	Drug exporters of the RND superfamily
ABOO_RS00120	COG1473	amidohydrolase
ABOO_RS00155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABOO_RS00160	COG2890	protein-(glutamine-N5) methyltransferase activity
ABOO_RS00200	COG0306	phosphate transporter
ABOO_RS00210	COG0549	Belongs to the carbamate kinase family
ABOO_RS00260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ABOO_RS00280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABOO_RS00295	COG0534	Mate efflux family protein
ABOO_RS00315	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABOO_RS00330	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABOO_RS00335	COG0693	protein deglycase activity
ABOO_RS00345	COG0243	molybdopterin cofactor binding
ABOO_RS00380	COG0049	tRNA binding
ABOO_RS00390	COG2895	sulfate adenylyltransferase (ATP) activity
ABOO_RS00395	COG0051	transcription antitermination factor activity, RNA binding
ABOO_RS00415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABOO_RS00420	COG0483	inositol monophosphate 1-phosphatase activity
ABOO_RS00425	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
ABOO_RS00445	COG0493	'glutamate synthase
ABOO_RS00445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABOO_RS00450	COG0543	2 iron, 2 sulfur cluster binding
ABOO_RS00455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABOO_RS00485	COG4974	Belongs to the 'phage' integrase family
ABOO_RS00495	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABOO_RS00535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ABOO_RS00540	COG0116	Belongs to the methyltransferase superfamily
ABOO_RS00540	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ABOO_RS00575	COG0314	molybdopterin synthase activity
ABOO_RS00580	COG1765	OsmC-like protein
ABOO_RS00605	COG0352	thiamine-phosphate diphosphorylase activity
ABOO_RS00610	COG1982	Orn Lys Arg decarboxylase major
ABOO_RS00615	COG2151	metal-sulfur cluster biosynthetic enzyme
ABOO_RS00620	COG1573	uracil-dna glycosylase
ABOO_RS00625	COG5002	protein histidine kinase activity
ABOO_RS00635	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABOO_RS00640	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
ABOO_RS00650	COG1121	(ABC) transporter
ABOO_RS00665	COG0066	3-isopropylmalate dehydratase activity
ABOO_RS00670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABOO_RS00700	COG3103	Sh3 type 3 domain protein
ABOO_RS00700	COG0366	Alpha amylase catalytic
ABOO_RS00790	COG0116	Belongs to the methyltransferase superfamily
ABOO_RS00805	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABOO_RS00815	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ABOO_RS00820	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABOO_RS00825	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ABOO_RS00860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABOO_RS00860	COG0473	3-isopropylmalate dehydrogenase activity
ABOO_RS00885	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABOO_RS00920	COG0456	acetyltransferase
ABOO_RS00930	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABOO_RS00935	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABOO_RS00940	COG1185	polyribonucleotide nucleotidyltransferase activity
ABOO_RS00965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABOO_RS00970	COG2255	four-way junction helicase activity
ABOO_RS01010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ABOO_RS01025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABOO_RS01025	COG1199	ATP-dependent helicase activity
ABOO_RS01030	COG1201	RNA secondary structure unwinding
ABOO_RS01045	COG0066	3-isopropylmalate dehydratase activity
ABOO_RS01055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABOO_RS01065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABOO_RS01080	COG4948	Mandelate Racemase Muconate Lactonizing
ABOO_RS01100	COG1444	tRNA N-acetyltransferase activity
ABOO_RS01115	COG0517	IMP dehydrogenase activity
ABOO_RS01130	COG1028	Short-chain dehydrogenase reductase Sdr
ABOO_RS01135	COG0546	phosphoglycolate phosphatase activity
ABOO_RS01140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABOO_RS01165	COG2094	Belongs to the DNA glycosylase MPG family
ABOO_RS01205	COG2046	Belongs to the sulfate adenylyltransferase family
ABOO_RS01220	COG0529	Catalyzes the synthesis of activated sulfate
ABOO_RS01225	COG0471	metal ion transport
ABOO_RS01260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ABOO_RS01270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABOO_RS01275	COG0438	transferase activity, transferring glycosyl groups
ABOO_RS01295	COG0438	transferase activity, transferring glycosyl groups
ABOO_RS01300	COG0463	Glycosyl transferase, family 2
ABOO_RS01300	COG1216	Glycosyl transferase, family 2
ABOO_RS01380	COG1573	uracil-dna glycosylase
ABOO_RS01390	COG0671	phosphoesterase, PA-phosphatase related
ABOO_RS01420	COG0531	amino acid
ABOO_RS01430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ABOO_RS01435	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABOO_RS01440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABOO_RS01450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABOO_RS01455	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABOO_RS01465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABOO_RS01475	COG0303	'Molybdopterin
ABOO_RS01500	COG1047	Peptidyl-prolyl cis-trans
ABOO_RS01515	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
ABOO_RS01530	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABOO_RS01535	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABOO_RS01540	COG1144	Oxidoreductase
ABOO_RS01560	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABOO_RS01575	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ABOO_RS01620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABOO_RS01620	COG0045	succinate-CoA ligase (ADP-forming) activity
ABOO_RS01620	COG1042	CoA-binding domain protein
ABOO_RS01630	COG3290	protein histidine kinase activity
ABOO_RS01630	COG3829	transcription factor binding
ABOO_RS01655	COG0517	IMP dehydrogenase activity
ABOO_RS01655	COG0516	GMP reductase activity
ABOO_RS01670	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ABOO_RS01680	COG0803	Belongs to the bacterial solute-binding protein 9 family
ABOO_RS01690	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ABOO_RS01690	COG0551	DNA topoisomerase type I activity
ABOO_RS01695	COG0719	Fe-S assembly protein
ABOO_RS01700	COG0396	ATPase activity
ABOO_RS01705	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ABOO_RS01710	COG0183	Belongs to the thiolase family
ABOO_RS01740	COG0714	Associated with various cellular activities
ABOO_RS01755	COG2131	deaminase
ABOO_RS01760	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ABOO_RS01765	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABOO_RS01765	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABOO_RS01795	COG0574	Belongs to the PEP-utilizing enzyme family
ABOO_RS01795	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABOO_RS01815	COG0157	Belongs to the NadC ModD family
ABOO_RS01820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABOO_RS01825	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ABOO_RS01840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABOO_RS01875	COG0300	oxidoreductase activity
ABOO_RS01895	COG0649	NAD binding
ABOO_RS01905	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABOO_RS01910	COG0650	Formate hydrogenlyase subunit 4
ABOO_RS01915	COG0651	ATP synthesis coupled electron transport
ABOO_RS01920	COG0651	ATP synthesis coupled electron transport
ABOO_RS01930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABOO_RS01930	COG2111	Na H antiporter
ABOO_RS01940	COG1320	monovalent cation:proton antiporter activity
ABOO_RS01945	COG2212	antiporter activity
ABOO_RS01950	COG1863	multisubunit Na H antiporter MnhE subunit
ABOO_RS01990	COG0823	Involved in the tonB-independent uptake of proteins
ABOO_RS01990	COG1506	peptidase
ABOO_RS01990	COG4946	Tricorn protease homolog
ABOO_RS02000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABOO_RS02010	COG1129	ABC transporter
ABOO_RS02015	COG0322	excinuclease ABC activity
ABOO_RS02020	COG4581	dead DEAH box helicase
ABOO_RS02030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABOO_RS02045	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABOO_RS02055	COG0747	negative chemotaxis
ABOO_RS02060	COG0601	transmembrane transport
ABOO_RS02070	COG0444	Belongs to the ABC transporter superfamily
ABOO_RS02075	COG4608	Belongs to the ABC transporter superfamily
ABOO_RS02085	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ABOO_RS02100	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABOO_RS02105	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABOO_RS02115	COG0490	domain, Protein
ABOO_RS02135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABOO_RS02145	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ABOO_RS02150	COG0436	Aminotransferase
ABOO_RS02165	COG0215	cysteine-tRNA ligase activity
ABOO_RS02180	COG1980	fructose-bisphosphate aldolase activity
ABOO_RS02190	COG1918	ferrous iron import across plasma membrane
ABOO_RS02190	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ABOO_RS02235	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ABOO_RS02240	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ABOO_RS02265	COG0006	proline dipeptidase activity
ABOO_RS02275	COG1739	Uncharacterized protein family UPF0029
ABOO_RS02280	COG1515	deoxyribonuclease V activity
ABOO_RS02285	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ABOO_RS02290	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ABOO_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
ABOO_RS02345	COG0017	Asparaginyl-tRNA synthetase
ABOO_RS02350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ABOO_RS02360	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ABOO_RS02365	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ABOO_RS02370	COG1994	Peptidase M50
ABOO_RS02390	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
ABOO_RS02410	COG1136	(ABC) transporter
ABOO_RS02420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABOO_RS02425	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABOO_RS02430	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABOO_RS02450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABOO_RS02450	COG0519	Catalyzes the synthesis of GMP from XMP
ABOO_RS02455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ABOO_RS02470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ABOO_RS02500	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABOO_RS02505	COG5002	protein histidine kinase activity
ABOO_RS02510	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ABOO_RS02520	COG1945	arginine decarboxylase activity
ABOO_RS02540	COG0330	HflC and HflK could
ABOO_RS02550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABOO_RS02555	COG2022	thiamine diphosphate biosynthetic process
ABOO_RS02585	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ABOO_RS02590	COG0477	Major facilitator Superfamily
ABOO_RS02600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABOO_RS02620	COG0489	protein tyrosine kinase activity
ABOO_RS02625	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ABOO_RS02655	COG2723	6-phospho-beta-galactosidase activity
ABOO_RS02660	COG2814	Major facilitator Superfamily
ABOO_RS02670	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ABOO_RS02675	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABOO_RS02690	COG0371	Dehydrogenase
ABOO_RS02720	COG0569	domain protein
ABOO_RS02725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABOO_RS02740	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABOO_RS02750	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ABOO_RS02820	COG0018	arginyl-trna synthetase
ABOO_RS02860	COG0546	phosphoglycolate phosphatase activity
ABOO_RS02870	COG0481	GTPase activity
ABOO_RS02905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABOO_RS02940	COG0436	Aminotransferase
ABOO_RS02960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABOO_RS02965	COG2140	Oxalate decarboxylase
ABOO_RS02990	COG1695	Transcriptional regulator
ABOO_RS03000	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ABOO_RS03010	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ABOO_RS03025	COG2379	hydroxypyruvate reductase
ABOO_RS03035	COG0519	Catalyzes the synthesis of GMP from XMP
ABOO_RS03035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABOO_RS03040	COG0598	Magnesium transport protein CorA
ABOO_RS03045	COG0126	phosphoglycerate kinase activity
ABOO_RS03050	COG0589	response to stress
ABOO_RS03055	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABOO_RS03085	COG2271	Major facilitator Superfamily
ABOO_RS03090	COG2945	thiolester hydrolase activity
ABOO_RS03180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABOO_RS03185	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ABOO_RS03190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ABOO_RS03230	COG2095	MarC family integral membrane protein
ABOO_RS03265	COG2264	protein methyltransferase activity
ABOO_RS03280	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ABOO_RS03285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ABOO_RS03290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABOO_RS03295	COG0720	synthase
ABOO_RS03305	COG4974	Belongs to the 'phage' integrase family
ABOO_RS03320	COG1522	sequence-specific DNA binding
ABOO_RS03325	COG1863	multisubunit Na H antiporter MnhE subunit
ABOO_RS03330	COG2212	antiporter activity
ABOO_RS03335	COG1320	monovalent cation:proton antiporter activity
ABOO_RS03360	COG2111	Na H antiporter
ABOO_RS03360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABOO_RS03370	COG3260	NADH ubiquinone oxidoreductase 20
ABOO_RS03375	COG0649	NAD binding
ABOO_RS03375	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABOO_RS03380	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ABOO_RS03380	COG3261	NADH dehydrogenase
ABOO_RS03385	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABOO_RS03390	COG4656	Part of a membrane complex involved in electron transport
ABOO_RS03395	COG0489	protein tyrosine kinase activity
ABOO_RS03410	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ABOO_RS03415	COG0409	Hydrogenase expression formation protein
ABOO_RS03420	COG0298	carbon dioxide binding
ABOO_RS03425	COG0640	Transcriptional regulator
ABOO_RS03450	COG1032	radical SAM domain protein
ABOO_RS03455	COG0535	radical SAM domain protein
ABOO_RS03480	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ABOO_RS03490	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABOO_RS03490	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABOO_RS03495	COG2814	Major facilitator Superfamily
ABOO_RS03500	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABOO_RS03505	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ABOO_RS03510	COG0163	prenyltransferase activity
ABOO_RS03525	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ABOO_RS03545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ABOO_RS03555	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABOO_RS03560	COG3958	Transketolase
ABOO_RS03565	COG3959	Transketolase, thiamine diphosphate binding domain
ABOO_RS03585	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ABOO_RS03600	COG2986	histidine ammonia-lyase
ABOO_RS03615	COG0312	modulator of DNA gyrase
ABOO_RS03630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ABOO_RS03635	COG1304	FMN binding
ABOO_RS03645	COG0442	prolyl-tRNA aminoacylation
ABOO_RS03655	COG0156	8-amino-7-oxononanoate synthase activity
ABOO_RS03660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABOO_RS03665	COG0367	asparagine synthase
ABOO_RS03670	COG0423	glycine-tRNA ligase activity
ABOO_RS03675	COG0517	IMP dehydrogenase activity
ABOO_RS03675	COG0617	tRNA 3'-terminal CCA addition
ABOO_RS03675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABOO_RS03685	COG0535	radical SAM domain protein
ABOO_RS03730	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ABOO_RS03745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABOO_RS03745	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABOO_RS03750	COG0004	ammonium transporteR
ABOO_RS03795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABOO_RS03810	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABOO_RS03850	COG0037	tRNA processing
ABOO_RS03865	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ABOO_RS03870	COG0109	protoheme IX farnesyltransferase activity
ABOO_RS03880	COG0651	ATP synthesis coupled electron transport
ABOO_RS03885	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABOO_RS03895	COG0651	ATP synthesis coupled electron transport
ABOO_RS03905	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ABOO_RS03920	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ABOO_RS03925	COG1469	GTP cyclohydrolase I activity
ABOO_RS03955	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ABOO_RS03965	COG0430	RNA-3'-phosphate cyclase activity
ABOO_RS03975	COG0504	CTP synthase activity
ABOO_RS03980	COG0297	glycogen (starch) synthase activity
ABOO_RS03995	COG0072	phenylalanine-tRNA ligase activity
ABOO_RS04015	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ABOO_RS04050	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ABOO_RS04055	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ABOO_RS04060	COG3383	formate dehydrogenase (NAD+) activity
ABOO_RS04065	COG0402	S-adenosylhomocysteine deaminase activity
ABOO_RS04070	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ABOO_RS04080	COG2414	aldehyde ferredoxin oxidoreductase
ABOO_RS04090	COG1793	dna ligase
ABOO_RS04100	COG1131	(ABC) transporter
ABOO_RS04120	COG0187	DNA topoisomerase II activity
ABOO_RS04125	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ABOO_RS04135	COG0708	Exodeoxyribonuclease III
ABOO_RS04170	COG1131	(ABC) transporter
ABOO_RS04180	COG0167	dihydroorotate dehydrogenase activity
ABOO_RS04185	COG1546	Belongs to the CinA family
ABOO_RS04185	COG1058	Belongs to the CinA family
ABOO_RS04190	COG1051	belongs to the nudix hydrolase family
ABOO_RS04190	COG1056	cytidyltransferase-related domain
ABOO_RS04205	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ABOO_RS04210	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ABOO_RS04230	COG0601	transmembrane transport
ABOO_RS04235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABOO_RS04240	COG0444	Belongs to the ABC transporter superfamily
ABOO_RS04245	COG4608	Belongs to the ABC transporter superfamily
ABOO_RS04250	COG0017	Asparaginyl-tRNA synthetase
ABOO_RS04270	COG0138	bifunctional purine biosynthesis protein purh
ABOO_RS04275	COG2201	protein-glutamate methylesterase activity
ABOO_RS04295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABOO_RS04330	COG0081	regulation of translation
ABOO_RS04335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ABOO_RS04350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABOO_RS04355	COG0475	glutathione-regulated potassium exporter activity
ABOO_RS04355	COG0569	domain protein
ABOO_RS04360	COG1028	Short-chain dehydrogenase reductase Sdr
ABOO_RS04365	COG1051	belongs to the nudix hydrolase family
ABOO_RS04375	COG1489	DNA binding
ABOO_RS04385	COG1773	rubredoxin
ABOO_RS04385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABOO_RS04395	COG1773	rubredoxin
ABOO_RS04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABOO_RS04410	COG1592	Rubrerythrin
ABOO_RS04415	COG1528	Iron-storage protein
ABOO_RS04420	COG2033	superoxide reductase activity
ABOO_RS04435	COG0450	alkyl hydroperoxide reductase
ABOO_RS04445	COG0584	glycerophosphoryl diester phosphodiesterase
ABOO_RS04455	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ABOO_RS04485	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ABOO_RS04505	COG0719	Fe-S assembly protein
ABOO_RS04515	COG1141	Ferredoxin
ABOO_RS04535	COG0300	oxidoreductase activity
ABOO_RS04545	COG0494	nUDIX hydrolase
ABOO_RS04580	COG2151	metal-sulfur cluster biosynthetic enzyme
ABOO_RS04590	COG0047	phosphoribosylformylglycinamidine synthase activity
ABOO_RS04595	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABOO_RS04620	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABOO_RS04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABOO_RS04660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABOO_RS04685	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ABOO_RS04700	COG1342	Belongs to the UPF0251 family
ABOO_RS04705	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ABOO_RS04710	COG0668	transmembrane transport
ABOO_RS04730	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABOO_RS04735	COG2252	PERMEase
ABOO_RS04740	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABOO_RS04745	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ABOO_RS04770	COG0469	pyruvate kinase activity
ABOO_RS04795	COG1110	DNA topoisomerase II activity
ABOO_RS04815	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ABOO_RS04820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABOO_RS04855	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ABOO_RS04860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABOO_RS04880	COG3052	prosthetic group binding
ABOO_RS04925	COG1446	asparaginase
ABOO_RS04935	COG2048	Heterodisulfide reductase, subunit B
ABOO_RS04965	COG1053	succinate dehydrogenase
ABOO_RS04980	COG0281	malic enzyme
ABOO_RS04990	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ABOO_RS05005	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ABOO_RS05010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ABOO_RS05015	COG0477	Major facilitator Superfamily
ABOO_RS05110	COG1401	restriction endodeoxyribonuclease activity
ABOO_RS05150	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ABOO_RS05155	COG1518	maintenance of DNA repeat elements
ABOO_RS05190	COG1337	RAMP superfamily
ABOO_RS05300	COG3620	sequence-specific DNA binding
ABOO_RS05425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABOO_RS05450	COG1011	Hydrolase
ABOO_RS05460	COG0745	RESPONSE REGULATOR receiver
ABOO_RS05470	COG1850	ribulose-bisphosphate carboxylase activity
ABOO_RS05500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ABOO_RS05505	COG0085	RNA polymerase activity
ABOO_RS05525	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ABOO_RS05560	COG0151	Belongs to the GarS family
ABOO_RS05565	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ABOO_RS05575	COG0322	excinuclease ABC activity
ABOO_RS05590	COG1321	iron dependent repressor
ABOO_RS05595	COG0095	Lipoate-protein ligase
ABOO_RS05605	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ABOO_RS05605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ABOO_RS05615	COG0301	tRNA thio-modification
ABOO_RS05630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABOO_RS05640	COG2414	aldehyde ferredoxin oxidoreductase
ABOO_RS05650	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ABOO_RS05665	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ABOO_RS05670	COG0540	Belongs to the ATCase OTCase family
ABOO_RS05690	COG0142	geranyltranstransferase activity
ABOO_RS05705	COG1131	(ABC) transporter
ABOO_RS05710	COG1505	serine-type exopeptidase activity
ABOO_RS05715	COG1078	dGTPase activity
ABOO_RS05720	COG0459	protein refolding
ABOO_RS05725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ABOO_RS05750	COG1394	ATPase activity, coupled to movement of substances
ABOO_RS05755	COG0284	orotidine-5'-phosphate decarboxylase activity
ABOO_RS05780	COG0037	tRNA processing
ABOO_RS05795	COG0306	phosphate transporter
ABOO_RS05820	COG1185	polyribonucleotide nucleotidyltransferase activity
ABOO_RS05835	COG0731	radical SAM domain protein
ABOO_RS05835	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ABOO_RS05840	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ABOO_RS05850	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABOO_RS05865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABOO_RS05870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABOO_RS05905	COG1254	Belongs to the acylphosphatase family
ABOO_RS05910	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABOO_RS05925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABOO_RS05980	COG0647	UMP catabolic process
ABOO_RS05985	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABOO_RS06015	COG0528	UMP kinase activity
ABOO_RS06025	COG2201	protein-glutamate methylesterase activity
ABOO_RS06070	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ABOO_RS06075	COG0668	transmembrane transport
ABOO_RS06080	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABOO_RS06165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABOO_RS06170	COG2255	four-way junction helicase activity
ABOO_RS06185	COG1201	RNA secondary structure unwinding
ABOO_RS06190	COG0252	asparaginase activity
ABOO_RS06195	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABOO_RS06210	COG1213	nucleotidyl transferase
ABOO_RS06210	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABOO_RS06230	COG0312	modulator of DNA gyrase
ABOO_RS06235	COG0312	modulator of DNA gyrase
ABOO_RS06240	COG0517	IMP dehydrogenase activity
ABOO_RS06245	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABOO_RS06265	COG0105	UTP biosynthetic process
ABOO_RS06270	COG0585	pseudouridine synthase activity
ABOO_RS06325	COG4608	Belongs to the ABC transporter superfamily
ABOO_RS06330	COG0444	Belongs to the ABC transporter superfamily
ABOO_RS06335	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABOO_RS06340	COG0601	transmembrane transport
ABOO_RS06345	COG0747	negative chemotaxis
ABOO_RS06360	COG0552	protein localization to endoplasmic reticulum
ABOO_RS06365	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABOO_RS06375	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ABOO_RS06400	COG1269	ATP hydrolysis coupled proton transport
ABOO_RS06410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ABOO_RS06415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ABOO_RS06420	COG1984	allophanate hydrolase subunit 2
ABOO_RS06425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ABOO_RS06430	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ABOO_RS06435	COG1132	(ABC) transporter
ABOO_RS06440	COG1132	(ABC) transporter
ABOO_RS06455	COG0492	ferredoxin-NADP+ reductase activity
ABOO_RS06475	COG0475	glutathione-regulated potassium exporter activity
ABOO_RS06495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ABOO_RS06500	COG0459	protein refolding
ABOO_RS06505	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ABOO_RS06510	COG0492	ferredoxin-NADP+ reductase activity
ABOO_RS06515	COG1335	isochorismatase
ABOO_RS06520	COG1228	amidohydrolase
ABOO_RS06530	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
ABOO_RS06535	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ABOO_RS06550	COG0315	cyclic pyranopterin monophosphate synthase activity
ABOO_RS06565	COG1362	aminopeptidase activity
ABOO_RS06570	COG1355	regulation of microtubule-based process
ABOO_RS06575	COG0052	Belongs to the universal ribosomal protein uS2 family
ABOO_RS06580	COG0148	phosphopyruvate hydratase activity
ABOO_RS06590	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ABOO_RS06605	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ABOO_RS06605	COG0517	IMP dehydrogenase activity
ABOO_RS06605	COG0617	tRNA 3'-terminal CCA addition
ABOO_RS06630	COG1335	isochorismatase
ABOO_RS06640	COG0417	DNA replication proofreading
ABOO_RS06655	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ABOO_RS06675	COG0083	homoserine kinase activity
ABOO_RS06695	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ABOO_RS06700	COG0509	glycine decarboxylation via glycine cleavage system
ABOO_RS06705	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ABOO_RS06720	COG0572	uridine kinase
ABOO_RS06745	COG4285	Biotin-protein ligase, N terminal
ABOO_RS06750	COG4608	Belongs to the ABC transporter superfamily
ABOO_RS06755	COG0444	Belongs to the ABC transporter superfamily
ABOO_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABOO_RS06760	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABOO_RS06765	COG0601	transmembrane transport
ABOO_RS06770	COG0747	negative chemotaxis
ABOO_RS06775	COG2414	aldehyde ferredoxin oxidoreductase
ABOO_RS06790	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ABOO_RS06795	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ABOO_RS06810	COG0484	heat shock protein binding
ABOO_RS06825	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ABOO_RS06850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABOO_RS06850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABOO_RS06860	COG0346	lactoylglutathione lyase activity
ABOO_RS06865	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABOO_RS06865	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ABOO_RS06870	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABOO_RS06880	COG0511	ligase activity, forming carbon-carbon bonds
ABOO_RS06885	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ABOO_RS06895	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ABOO_RS06905	COG0310	cobalt ion transport
ABOO_RS06910	COG0864	Transcriptional regulator
ABOO_RS06960	COG1196	nuclear chromosome segregation
ABOO_RS06975	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABOO_RS07000	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ABOO_RS07025	COG0470	DNA polymerase III
ABOO_RS07025	COG1067	ATP-dependent peptidase activity
ABOO_RS07035	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ABOO_RS07040	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ABOO_RS07070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABOO_RS07075	COG4208	sulfate ABC transporter
ABOO_RS07080	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABOO_RS07100	COG2078	PFAM AMMECR1 domain protein
ABOO_RS07100	COG3885	ferrous iron binding
ABOO_RS07105	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ABOO_RS07140	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ABOO_RS07140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABOO_RS07150	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ABOO_RS07165	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABOO_RS07170	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ABOO_RS07180	COG0174	glutamine synthetase
ABOO_RS07190	COG1234	tRNA 3'-trailer cleavage
ABOO_RS07240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABOO_RS07245	COG0174	glutamine synthetase
ABOO_RS07255	COG1013	pyruvate-flavodoxin oxidoreductase activity
ABOO_RS07260	COG0674	pyruvate-flavodoxin oxidoreductase activity
ABOO_RS07275	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ABOO_RS07305	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ABOO_RS07315	COG2078	PFAM AMMECR1 domain protein
ABOO_RS07320	COG0602	queuosine metabolic process
ABOO_RS07335	COG0006	proline dipeptidase activity
ABOO_RS07340	COG0534	Mate efflux family protein
ABOO_RS07385	COG0473	3-isopropylmalate dehydrogenase activity
ABOO_RS07395	COG0066	3-isopropylmalate dehydratase activity
ABOO_RS07405	COG0372	Belongs to the citrate synthase family
ABOO_RS07410	COG0402	S-adenosylhomocysteine deaminase activity
ABOO_RS07420	COG0495	leucyl-tRNA aminoacylation
ABOO_RS07435	COG2358	TRAP transporter, solute receptor (TAXI family
ABOO_RS07445	COG0200	Binds to the 23S rRNA
ABOO_RS07455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABOO_RS07470	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ABOO_RS07560	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABOO_RS07565	COG0563	adenylate kinase activity
ABOO_RS07620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ABOO_RS07640	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ABOO_RS07645	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ABOO_RS07650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ABOO_RS07660	COG0255	Belongs to the universal ribosomal protein uL29 family
ABOO_RS07665	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ABOO_RS07675	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ABOO_RS07680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ABOO_RS07685	COG0089	rRNA binding
ABOO_RS07695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ABOO_RS07700	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ABOO_RS07715	COG0101	tRNA pseudouridine synthase activity
ABOO_RS07735	COG4946	Tricorn protease homolog
ABOO_RS07735	COG1506	peptidase
ABOO_RS07735	COG0823	Involved in the tonB-independent uptake of proteins
ABOO_RS07745	COG0492	ferredoxin-NADP+ reductase activity
ABOO_RS07750	COG0579	oxidoreductase
ABOO_RS07760	COG0544	peptidyl-prolyl cis-trans isomerase activity
ABOO_RS07770	COG1378	Sugar-specific transcriptional regulator TrmB
ABOO_RS07775	COG2204	response regulator
ABOO_RS07780	COG1574	metal-dependent hydrolase with the TIM-barrel fold
ABOO_RS07785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABOO_RS07795	COG2414	aldehyde ferredoxin oxidoreductase
ABOO_RS07810	COG2050	protein possibly involved in aromatic compounds catabolism
ABOO_RS07810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ABOO_RS07830	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABOO_RS07835	COG0477	Major facilitator Superfamily
ABOO_RS07840	COG0285	dihydrofolate synthase activity
ABOO_RS07845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis