locus-tag	class	description
ACIM339_RS00015	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACIM339_RS00020	COG0010	Belongs to the arginase family
ACIM339_RS00065	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACIM339_RS00110	COG2409	Drug exporters of the RND superfamily
ACIM339_RS00120	COG1473	amidohydrolase
ACIM339_RS00155	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACIM339_RS00200	COG0306	phosphate transporter
ACIM339_RS00210	COG1982	Orn Lys Arg decarboxylase major
ACIM339_RS00230	COG2814	Major facilitator Superfamily
ACIM339_RS00235	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ACIM339_RS00260	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS00285	COG0124	histidyl-tRNA synthetase
ACIM339_RS00290	COG0534	Mate efflux family protein
ACIM339_RS00300	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACIM339_RS00300	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACIM339_RS00310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACIM339_RS00315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACIM339_RS00320	COG2252	PERMEase
ACIM339_RS00325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACIM339_RS00345	COG0668	transmembrane transport
ACIM339_RS00350	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ACIM339_RS00355	COG1342	Belongs to the UPF0251 family
ACIM339_RS00395	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIM339_RS00425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACIM339_RS00455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACIM339_RS00460	COG0047	phosphoribosylformylglycinamidine synthase activity
ACIM339_RS00470	COG2151	metal-sulfur cluster biosynthetic enzyme
ACIM339_RS00500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACIM339_RS00515	COG1028	Short-chain dehydrogenase reductase Sdr
ACIM339_RS00535	COG1141	Ferredoxin
ACIM339_RS00555	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ACIM339_RS00565	COG0501	Belongs to the peptidase M48B family
ACIM339_RS00585	COG0436	Aminotransferase
ACIM339_RS00595	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
ACIM339_RS00605	COG0584	glycerophosphoryl diester phosphodiesterase
ACIM339_RS00615	COG0450	alkyl hydroperoxide reductase
ACIM339_RS00620	COG0557	exoribonuclease II activity
ACIM339_RS00630	COG2033	superoxide reductase activity
ACIM339_RS00635	COG1528	Iron-storage protein
ACIM339_RS00645	COG1592	Rubrerythrin
ACIM339_RS00650	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ACIM339_RS00660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACIM339_RS00665	COG0426	domain, Protein
ACIM339_RS00670	COG1773	rubredoxin
ACIM339_RS00675	COG1773	rubredoxin
ACIM339_RS00675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACIM339_RS00680	COG1522	sequence-specific DNA binding
ACIM339_RS00685	COG1489	DNA binding
ACIM339_RS00695	COG1051	belongs to the nudix hydrolase family
ACIM339_RS00700	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIM339_RS00715	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACIM339_RS00720	COG0081	regulation of translation
ACIM339_RS00725	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACIM339_RS00750	COG0488	(ABC) transporter
ACIM339_RS00760	COG0138	bifunctional purine biosynthesis protein purh
ACIM339_RS00775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACIM339_RS00780	COG0017	Asparaginyl-tRNA synthetase
ACIM339_RS00785	COG4608	Belongs to the ABC transporter superfamily
ACIM339_RS00790	COG0444	Belongs to the ABC transporter superfamily
ACIM339_RS00795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACIM339_RS00800	COG0601	transmembrane transport
ACIM339_RS00820	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACIM339_RS00875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACIM339_RS01010	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACIM339_RS01105	COG1056	cytidyltransferase-related domain
ACIM339_RS01105	COG1051	belongs to the nudix hydrolase family
ACIM339_RS01110	COG1546	Belongs to the CinA family
ACIM339_RS01110	COG1058	Belongs to the CinA family
ACIM339_RS01115	COG0167	dihydroorotate dehydrogenase activity
ACIM339_RS01120	COG0543	2 iron, 2 sulfur cluster binding
ACIM339_RS01150	COG2894	cell division
ACIM339_RS01160	COG0708	Exodeoxyribonuclease III
ACIM339_RS01170	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACIM339_RS01175	COG0187	DNA topoisomerase II activity
ACIM339_RS01205	COG1793	dna ligase
ACIM339_RS01225	COG0649	NAD binding
ACIM339_RS01230	COG0651	ATP synthesis coupled electron transport
ACIM339_RS01240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACIM339_RS01245	COG2414	aldehyde ferredoxin oxidoreductase
ACIM339_RS01260	COG0402	S-adenosylhomocysteine deaminase activity
ACIM339_RS01265	COG3383	formate dehydrogenase (NAD+) activity
ACIM339_RS01270	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACIM339_RS01275	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ACIM339_RS01310	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS01330	COG0072	phenylalanine-tRNA ligase activity
ACIM339_RS01340	COG0297	glycogen (starch) synthase activity
ACIM339_RS01345	COG0504	CTP synthase activity
ACIM339_RS01355	COG0430	RNA-3'-phosphate cyclase activity
ACIM339_RS01360	COG0457	Tetratricopeptide repeat
ACIM339_RS01360	COG0705	Rhomboid family
ACIM339_RS01365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACIM339_RS01380	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACIM339_RS01400	COG0109	protoheme IX farnesyltransferase activity
ACIM339_RS01405	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
ACIM339_RS01420	COG0037	tRNA processing
ACIM339_RS01445	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACIM339_RS01460	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIM339_RS01465	COG0009	L-threonylcarbamoyladenylate synthase
ACIM339_RS01470	COG0024	Methionine aminopeptidase
ACIM339_RS01515	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACIM339_RS01530	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACIM339_RS01570	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACIM339_RS01575	COG0535	radical SAM domain protein
ACIM339_RS01585	COG0517	IMP dehydrogenase activity
ACIM339_RS01585	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACIM339_RS01585	COG0617	tRNA 3'-terminal CCA addition
ACIM339_RS01590	COG0423	glycine-tRNA ligase activity
ACIM339_RS01595	COG0367	asparagine synthase
ACIM339_RS01600	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACIM339_RS01605	COG0156	8-amino-7-oxononanoate synthase activity
ACIM339_RS01620	COG0442	prolyl-tRNA aminoacylation
ACIM339_RS01635	COG1304	FMN binding
ACIM339_RS01650	COG0312	modulator of DNA gyrase
ACIM339_RS01655	COG0312	modulator of DNA gyrase
ACIM339_RS01665	COG2986	histidine ammonia-lyase
ACIM339_RS01680	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS01700	COG3959	Transketolase, thiamine diphosphate binding domain
ACIM339_RS01705	COG3958	Transketolase
ACIM339_RS01710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACIM339_RS01720	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACIM339_RS01725	COG0025	NhaP-type Na H and K H
ACIM339_RS01735	COG0163	prenyltransferase activity
ACIM339_RS01740	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACIM339_RS01755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACIM339_RS01755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACIM339_RS01765	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACIM339_RS01770	COG1522	sequence-specific DNA binding
ACIM339_RS01805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACIM339_RS01810	COG4974	Belongs to the 'phage' integrase family
ACIM339_RS01820	COG0720	synthase
ACIM339_RS01825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACIM339_RS01830	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACIM339_RS01835	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACIM339_RS01850	COG2264	protein methyltransferase activity
ACIM339_RS01875	COG2095	MarC family integral membrane protein
ACIM339_RS01915	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ACIM339_RS01925	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACIM339_RS02005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACIM339_RS02020	COG2223	nitrite transmembrane transporter activity
ACIM339_RS02050	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACIM339_RS02060	COG0126	phosphoglycerate kinase activity
ACIM339_RS02065	COG0598	Magnesium transport protein CorA
ACIM339_RS02070	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACIM339_RS02070	COG0519	Catalyzes the synthesis of GMP from XMP
ACIM339_RS02085	COG0535	radical SAM domain protein
ACIM339_RS02130	COG2379	hydroxypyruvate reductase
ACIM339_RS02150	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ACIM339_RS02160	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
ACIM339_RS02170	COG1695	Transcriptional regulator
ACIM339_RS02195	COG2140	Oxalate decarboxylase
ACIM339_RS02200	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIM339_RS02220	COG0436	Aminotransferase
ACIM339_RS02255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACIM339_RS02315	COG0546	phosphoglycolate phosphatase activity
ACIM339_RS02350	COG0018	arginyl-trna synthetase
ACIM339_RS02380	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS02390	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS02400	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ACIM339_RS02410	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACIM339_RS02425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACIM339_RS02430	COG0569	domain protein
ACIM339_RS02450	COG0012	GTP binding
ACIM339_RS02460	COG0371	Dehydrogenase
ACIM339_RS02480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACIM339_RS02505	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
ACIM339_RS02510	COG0489	protein tyrosine kinase activity
ACIM339_RS02545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACIM339_RS02590	COG2255	four-way junction helicase activity
ACIM339_RS02600	COG0330	HflC and HflK could
ACIM339_RS02620	COG1945	arginine decarboxylase activity
ACIM339_RS02630	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACIM339_RS02675	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACIM339_RS02680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACIM339_RS02680	COG0519	Catalyzes the synthesis of GMP from XMP
ACIM339_RS02700	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACIM339_RS02705	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACIM339_RS02710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACIM339_RS02720	COG1136	(ABC) transporter
ACIM339_RS02735	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
ACIM339_RS02755	COG1994	Peptidase M50
ACIM339_RS02760	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACIM339_RS02765	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
ACIM339_RS02790	COG0017	Asparaginyl-tRNA synthetase
ACIM339_RS02840	COG1028	Short-chain dehydrogenase reductase Sdr
ACIM339_RS02855	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ACIM339_RS02860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACIM339_RS02865	COG1515	deoxyribonuclease V activity
ACIM339_RS02870	COG1739	Uncharacterized protein family UPF0029
ACIM339_RS02880	COG0006	proline dipeptidase activity
ACIM339_RS02895	COG0745	RESPONSE REGULATOR receiver
ACIM339_RS02920	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ACIM339_RS02965	COG1918	ferrous iron import across plasma membrane
ACIM339_RS02965	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACIM339_RS02975	COG1980	fructose-bisphosphate aldolase activity
ACIM339_RS02995	COG0215	cysteine-tRNA ligase activity
ACIM339_RS03000	COG2414	aldehyde ferredoxin oxidoreductase
ACIM339_RS03010	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ACIM339_RS03050	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACIM339_RS03055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACIM339_RS03070	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACIM339_RS03080	COG4608	Belongs to the ABC transporter superfamily
ACIM339_RS03085	COG0444	Belongs to the ABC transporter superfamily
ACIM339_RS03090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACIM339_RS03095	COG0601	transmembrane transport
ACIM339_RS03100	COG0747	negative chemotaxis
ACIM339_RS03130	COG0322	excinuclease ABC activity
ACIM339_RS03135	COG1129	ABC transporter
ACIM339_RS03145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACIM339_RS03155	COG0823	Involved in the tonB-independent uptake of proteins
ACIM339_RS03155	COG1506	peptidase
ACIM339_RS03155	COG4946	Tricorn protease homolog
ACIM339_RS03170	COG1863	multisubunit Na H antiporter MnhE subunit
ACIM339_RS03175	COG2212	antiporter activity
ACIM339_RS03190	COG2111	Na H antiporter
ACIM339_RS03190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACIM339_RS03195	COG1006	Multisubunit Na H antiporter MnhC subunit
ACIM339_RS03200	COG0651	ATP synthesis coupled electron transport
ACIM339_RS03205	COG0651	ATP synthesis coupled electron transport
ACIM339_RS03210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACIM339_RS03215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIM339_RS03220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIM339_RS03225	COG0649	NAD binding
ACIM339_RS03230	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIM339_RS03250	COG0300	oxidoreductase activity
ACIM339_RS03285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACIM339_RS03305	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACIM339_RS03310	COG0157	Belongs to the NadC ModD family
ACIM339_RS03325	COG0574	Belongs to the PEP-utilizing enzyme family
ACIM339_RS03325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACIM339_RS03355	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACIM339_RS03355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACIM339_RS03365	COG0501	Belongs to the peptidase M48B family
ACIM339_RS03405	COG2131	deaminase
ACIM339_RS03420	COG0714	Associated with various cellular activities
ACIM339_RS03465	COG4974	Belongs to the 'phage' integrase family
ACIM339_RS03475	COG0183	Belongs to the thiolase family
ACIM339_RS03480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACIM339_RS03485	COG0396	ATPase activity
ACIM339_RS03490	COG0719	Fe-S assembly protein
ACIM339_RS03495	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACIM339_RS03505	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACIM339_RS03520	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACIM339_RS03535	COG0516	GMP reductase activity
ACIM339_RS03535	COG0517	IMP dehydrogenase activity
ACIM339_RS03550	COG0475	glutathione-regulated potassium exporter activity
ACIM339_RS03590	COG1137	ATPase activity
ACIM339_RS03605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACIM339_RS03605	COG1042	CoA-binding domain protein
ACIM339_RS03605	COG0045	succinate-CoA ligase (ADP-forming) activity
ACIM339_RS03655	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACIM339_RS03670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACIM339_RS03690	COG1144	Oxidoreductase
ACIM339_RS03695	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIM339_RS03700	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIM339_RS03715	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
ACIM339_RS03730	COG1047	Peptidyl-prolyl cis-trans
ACIM339_RS03745	COG2814	Major facilitator Superfamily
ACIM339_RS03750	COG0303	'Molybdopterin
ACIM339_RS03770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACIM339_RS03780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACIM339_RS03785	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACIM339_RS03790	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACIM339_RS03800	COG0531	amino acid
ACIM339_RS03815	COG1131	(ABC) transporter
ACIM339_RS03820	COG0842	Transport permease protein
ACIM339_RS03845	COG1213	nucleotidyl transferase
ACIM339_RS03850	COG0367	asparagine synthase
ACIM339_RS03855	COG1373	ATPase (AAA superfamily
ACIM339_RS03890	COG0438	transferase activity, transferring glycosyl groups
ACIM339_RS03900	COG0438	transferase activity, transferring glycosyl groups
ACIM339_RS03915	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACIM339_RS03930	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACIM339_RS03940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACIM339_RS03945	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACIM339_RS03950	COG0673	inositol 2-dehydrogenase activity
ACIM339_RS04000	COG2094	Belongs to the DNA glycosylase MPG family
ACIM339_RS04020	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACIM339_RS04025	COG0546	phosphoglycolate phosphatase activity
ACIM339_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
ACIM339_RS04050	COG1444	tRNA N-acetyltransferase activity
ACIM339_RS04070	COG4948	Mandelate Racemase Muconate Lactonizing
ACIM339_RS04085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACIM339_RS04095	COG1760	l-serine dehydratase
ACIM339_RS04100	COG1760	l-serine dehydratase
ACIM339_RS04105	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACIM339_RS04110	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACIM339_RS04120	COG0066	3-isopropylmalate dehydratase activity
ACIM339_RS04125	COG1201	RNA secondary structure unwinding
ACIM339_RS04145	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ACIM339_RS04175	COG2255	four-way junction helicase activity
ACIM339_RS04180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACIM339_RS04200	COG1185	polyribonucleotide nucleotidyltransferase activity
ACIM339_RS04205	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACIM339_RS04225	COG0456	acetyltransferase
ACIM339_RS04245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIM339_RS04270	COG0473	3-isopropylmalate dehydrogenase activity
ACIM339_RS04270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACIM339_RS04305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACIM339_RS04310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACIM339_RS04315	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACIM339_RS04325	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACIM339_RS04335	COG0116	Belongs to the methyltransferase superfamily
ACIM339_RS04435	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACIM339_RS04440	COG0066	3-isopropylmalate dehydratase activity
ACIM339_RS04455	COG1121	(ABC) transporter
ACIM339_RS04470	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ACIM339_RS04480	COG5002	protein histidine kinase activity
ACIM339_RS04480	COG3850	Histidine kinase
ACIM339_RS04485	COG1573	uracil-dna glycosylase
ACIM339_RS04490	COG2151	metal-sulfur cluster biosynthetic enzyme
ACIM339_RS04495	COG0730	response to heat
ACIM339_RS04505	COG0006	proline dipeptidase activity
ACIM339_RS04535	COG0352	thiamine-phosphate diphosphorylase activity
ACIM339_RS04580	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACIM339_RS04585	COG0584	glycerophosphoryl diester phosphodiesterase
ACIM339_RS04615	COG0587	DNA-directed DNA polymerase activity
ACIM339_RS04620	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACIM339_RS04625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACIM339_RS04630	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACIM339_RS04655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACIM339_RS04670	COG0543	2 iron, 2 sulfur cluster binding
ACIM339_RS04675	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACIM339_RS04675	COG0493	'glutamate synthase
ACIM339_RS04725	COG0051	transcription antitermination factor activity, RNA binding
ACIM339_RS04730	COG2895	sulfate adenylyltransferase (ATP) activity
ACIM339_RS04740	COG0049	tRNA binding
ACIM339_RS04775	COG0243	molybdopterin cofactor binding
ACIM339_RS04780	COG0693	protein deglycase activity
ACIM339_RS04785	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACIM339_RS04800	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIM339_RS04830	COG0765	amino acid transport
ACIM339_RS04835	COG1126	abc transporter atp-binding protein
ACIM339_RS04845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACIM339_RS04860	COG1110	DNA topoisomerase II activity
ACIM339_RS04880	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACIM339_RS04885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACIM339_RS04895	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACIM339_RS04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACIM339_RS04920	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
ACIM339_RS04940	COG0004	ammonium transporteR
ACIM339_RS04955	COG2301	Belongs to the HpcH HpaI aldolase family
ACIM339_RS04985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACIM339_RS04990	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACIM339_RS04995	COG0200	Binds to the 23S rRNA
ACIM339_RS05015	COG0495	leucyl-tRNA aminoacylation
ACIM339_RS05025	COG0671	phosphoesterase, PA-phosphatase related
ACIM339_RS05030	COG0402	S-adenosylhomocysteine deaminase activity
ACIM339_RS05035	COG0372	Belongs to the citrate synthase family
ACIM339_RS05045	COG0066	3-isopropylmalate dehydratase activity
ACIM339_RS05055	COG0473	3-isopropylmalate dehydrogenase activity
ACIM339_RS05075	COG0494	nUDIX hydrolase
ACIM339_RS05095	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACIM339_RS05105	COG0534	Mate efflux family protein
ACIM339_RS05125	COG0602	queuosine metabolic process
ACIM339_RS05130	COG2078	PFAM AMMECR1 domain protein
ACIM339_RS05135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACIM339_RS05170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACIM339_RS05185	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACIM339_RS05190	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACIM339_RS05195	COG0076	glutamate decarboxylase activity
ACIM339_RS05200	COG0174	glutamine synthetase
ACIM339_RS05205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACIM339_RS05210	COG1363	Peptidase, m42
ACIM339_RS05250	COG0180	Tryptophanyl-tRNA synthetase
ACIM339_RS05255	COG1234	tRNA 3'-trailer cleavage
ACIM339_RS05270	COG0579	oxidoreductase
ACIM339_RS05285	COG0823	Involved in the tonB-independent uptake of proteins
ACIM339_RS05285	COG1506	peptidase
ACIM339_RS05285	COG4946	Tricorn protease homolog
ACIM339_RS05305	COG0101	tRNA pseudouridine synthase activity
ACIM339_RS05320	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ACIM339_RS05330	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACIM339_RS05350	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACIM339_RS05360	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACIM339_RS05365	COG0255	Belongs to the universal ribosomal protein uL29 family
ACIM339_RS05375	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACIM339_RS05380	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACIM339_RS05385	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ACIM339_RS05395	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACIM339_RS05405	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACIM339_RS05410	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACIM339_RS05435	COG1841	ribosomal large subunit assembly
ACIM339_RS05460	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACIM339_RS05465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACIM339_RS05510	COG2048	Heterodisulfide reductase, subunit B
ACIM339_RS05540	COG1053	succinate dehydrogenase
ACIM339_RS05555	COG0281	malic enzyme
ACIM339_RS05560	COG0045	succinate-CoA ligase (ADP-forming) activity
ACIM339_RS05565	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACIM339_RS05570	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACIM339_RS05580	COG1122	ATPase activity
ACIM339_RS05585	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACIM339_RS05595	COG0310	cobalt ion transport
ACIM339_RS05605	COG0864	Transcriptional regulator
ACIM339_RS05610	COG1863	multisubunit Na H antiporter MnhE subunit
ACIM339_RS05615	COG2212	antiporter activity
ACIM339_RS05620	COG1320	monovalent cation:proton antiporter activity
ACIM339_RS05645	COG2111	Na H antiporter
ACIM339_RS05645	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACIM339_RS05655	COG3260	NADH ubiquinone oxidoreductase 20
ACIM339_RS05660	COG0649	NAD binding
ACIM339_RS05660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACIM339_RS05665	COG3261	NADH dehydrogenase
ACIM339_RS05665	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ACIM339_RS05670	COG0650	Formate hydrogenlyase subunit 4
ACIM339_RS05675	COG4656	Part of a membrane complex involved in electron transport
ACIM339_RS05680	COG0489	protein tyrosine kinase activity
ACIM339_RS05695	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ACIM339_RS05700	COG0409	Hydrogenase expression formation protein
ACIM339_RS05705	COG0298	carbon dioxide binding
ACIM339_RS05720	COG0396	ATPase activity
ACIM339_RS05725	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACIM339_RS05725	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACIM339_RS05735	COG0346	lactoylglutathione lyase activity
ACIM339_RS05740	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACIM339_RS05740	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACIM339_RS05745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACIM339_RS05760	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
ACIM339_RS05805	COG1196	nuclear chromosome segregation
ACIM339_RS05820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIM339_RS05845	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACIM339_RS05875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACIM339_RS05935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACIM339_RS05990	COG1028	Short-chain dehydrogenase reductase Sdr
ACIM339_RS06000	COG0492	ferredoxin-NADP+ reductase activity
ACIM339_RS06040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACIM339_RS06045	COG0459	protein refolding
ACIM339_RS06050	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACIM339_RS06055	COG0492	ferredoxin-NADP+ reductase activity
ACIM339_RS06065	COG1228	amidohydrolase
ACIM339_RS06075	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
ACIM339_RS06085	COG0315	cyclic pyranopterin monophosphate synthase activity
ACIM339_RS06090	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACIM339_RS06095	COG1362	aminopeptidase activity
ACIM339_RS06100	COG1355	regulation of microtubule-based process
ACIM339_RS06105	COG0052	Belongs to the universal ribosomal protein uS2 family
ACIM339_RS06110	COG0148	phosphopyruvate hydratase activity
ACIM339_RS06120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACIM339_RS06135	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACIM339_RS06135	COG0517	IMP dehydrogenase activity
ACIM339_RS06135	COG0617	tRNA 3'-terminal CCA addition
ACIM339_RS06155	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ACIM339_RS06175	COG0417	DNA replication proofreading
ACIM339_RS06190	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACIM339_RS06230	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ACIM339_RS06235	COG0509	glycine decarboxylation via glycine cleavage system
ACIM339_RS06240	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACIM339_RS06255	COG0572	uridine kinase
ACIM339_RS06265	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACIM339_RS06275	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ACIM339_RS06290	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACIM339_RS06325	COG1269	ATP hydrolysis coupled proton transport
ACIM339_RS06350	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
ACIM339_RS06360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACIM339_RS06365	COG0552	protein localization to endoplasmic reticulum
ACIM339_RS06380	COG0747	negative chemotaxis
ACIM339_RS06385	COG0601	transmembrane transport
ACIM339_RS06390	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACIM339_RS06395	COG0444	Belongs to the ABC transporter superfamily
ACIM339_RS06400	COG4608	Belongs to the ABC transporter superfamily
ACIM339_RS06440	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACIM339_RS06445	COG1122	ATPase activity
ACIM339_RS06455	COG0585	pseudouridine synthase activity
ACIM339_RS06460	COG0105	UTP biosynthetic process
ACIM339_RS06480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACIM339_RS06485	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACIM339_RS06485	COG0517	IMP dehydrogenase activity
ACIM339_RS06485	COG0617	tRNA 3'-terminal CCA addition
ACIM339_RS06490	COG0312	modulator of DNA gyrase
ACIM339_RS06495	COG0312	modulator of DNA gyrase
ACIM339_RS06525	COG1213	nucleotidyl transferase
ACIM339_RS06525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACIM339_RS06540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACIM339_RS06545	COG0252	asparaginase activity
ACIM339_RS06550	COG1201	RNA secondary structure unwinding
ACIM339_RS06555	COG2255	four-way junction helicase activity
ACIM339_RS06560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACIM339_RS06570	COG2943	transferase activity, transferring hexosyl groups
ACIM339_RS06640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACIM339_RS06645	COG0668	transmembrane transport
ACIM339_RS06650	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ACIM339_RS06675	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACIM339_RS06710	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACIM339_RS06765	COG1011	Hydrolase
ACIM339_RS06785	COG1850	ribulose-bisphosphate carboxylase activity
ACIM339_RS06790	COG1396	sequence-specific DNA binding
ACIM339_RS06820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACIM339_RS06825	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACIM339_RS06830	COG0085	RNA polymerase activity
ACIM339_RS06850	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ACIM339_RS06885	COG0151	Belongs to the GarS family
ACIM339_RS06895	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ACIM339_RS06925	COG0322	excinuclease ABC activity
ACIM339_RS06980	COG1321	iron dependent repressor
ACIM339_RS06985	COG0095	Lipoate-protein ligase
ACIM339_RS06995	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACIM339_RS06995	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ACIM339_RS07005	COG0301	tRNA thio-modification
ACIM339_RS07020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACIM339_RS07030	COG2414	aldehyde ferredoxin oxidoreductase
ACIM339_RS07040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACIM339_RS07055	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ACIM339_RS07060	COG0540	Belongs to the ATCase OTCase family
ACIM339_RS07085	COG0142	geranyltranstransferase activity
ACIM339_RS07100	COG1131	(ABC) transporter
ACIM339_RS07105	COG1078	dGTPase activity
ACIM339_RS07110	COG0459	protein refolding
ACIM339_RS07115	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACIM339_RS07130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACIM339_RS07140	COG0284	orotidine-5'-phosphate decarboxylase activity
ACIM339_RS07165	COG0037	tRNA processing
ACIM339_RS07180	COG0306	phosphate transporter
ACIM339_RS07205	COG1185	polyribonucleotide nucleotidyltransferase activity
ACIM339_RS07220	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACIM339_RS07220	COG0731	radical SAM domain protein
ACIM339_RS07225	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACIM339_RS07245	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ACIM339_RS07280	COG1254	Belongs to the acylphosphatase family
ACIM339_RS07290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACIM339_RS07325	COG2414	aldehyde ferredoxin oxidoreductase
ACIM339_RS07330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACIM339_RS07350	COG0525	valine-tRNA ligase activity
ACIM339_RS07360	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ACIM339_RS07365	COG1518	maintenance of DNA repeat elements
ACIM339_RS07410	COG0647	UMP catabolic process
ACIM339_RS07415	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACIM339_RS07445	COG0528	UMP kinase activity
ACIM339_RS07455	COG2201	protein-glutamate methylesterase activity
ACIM339_RS07475	COG0174	glutamine synthetase
ACIM339_RS07485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACIM339_RS07490	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACIM339_RS07505	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACIM339_RS07510	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ACIM339_RS07510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACIM339_RS07530	COG0170	dolichyl monophosphate biosynthetic process
ACIM339_RS07545	COG0470	DNA polymerase III
ACIM339_RS07545	COG1067	ATP-dependent peptidase activity
ACIM339_RS07570	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACIM339_RS07575	COG4208	sulfate ABC transporter
ACIM339_RS07580	COG3842	ATPase activity
ACIM339_RS07605	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACIM339_RS07610	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACIM339_RS07615	COG0358	DNA primase activity
ACIM339_RS07620	COG0470	DNA polymerase III
ACIM339_RS07620	COG1067	ATP-dependent peptidase activity
ACIM339_RS07625	COG0295	cytidine deaminase activity
ACIM339_RS07640	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACIM339_RS07650	COG1378	Sugar-specific transcriptional regulator TrmB
ACIM339_RS07655	COG2204	response regulator
ACIM339_RS07665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACIM339_RS07675	COG2050	protein possibly involved in aromatic compounds catabolism
ACIM339_RS07675	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ACIM339_RS07695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACIM339_RS07700	COG0477	Major facilitator Superfamily
ACIM339_RS07705	COG0285	dihydrofolate synthase activity
ACIM339_RS07710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis