locus-tag	class	description
OIO71_RS00010	COG0592	DNA-directed DNA polymerase activity
OIO71_RS00020	COG0187	DNA topoisomerase II activity
OIO71_RS00030	COG0586	Pfam SNARE associated Golgi protein
OIO71_RS00035	COG0488	(ABC) transporter
OIO71_RS00060	COG0596	Alpha beta hydrolase
OIO71_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO71_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO71_RS00110	COG0733	neurotransmitter:sodium symporter activity
OIO71_RS00150	COG2233	PERMEase
OIO71_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS00200	COG2814	Major facilitator Superfamily
OIO71_RS00205	COG0656	L-ascorbic acid biosynthetic process
OIO71_RS00210	COG0583	DNA-binding transcription factor activity
OIO71_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO71_RS00230	COG1064	alcohol dehydrogenase
OIO71_RS00235	COG2818	Glycosylase
OIO71_RS00250	COG1194	a g-specific adenine glycosylase
OIO71_RS00270	COG2983	Belongs to the UPF0260 family
OIO71_RS00280	COG3121	Chaperone
OIO71_RS00285	COG3188	usher protein
OIO71_RS00300	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO71_RS00305	COG2116	formate transmembrane transporter activity
OIO71_RS00325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO71_RS00330	COG1335	isochorismatase
OIO71_RS00335	COG0385	Bile acid
OIO71_RS00340	COG0534	Mate efflux family protein
OIO71_RS00345	COG1683	Conserved Protein
OIO71_RS00365	COG0625	glutathione transferase activity
OIO71_RS00375	COG1113	amino acid transport
OIO71_RS00385	COG0523	cobalamin synthesis protein
OIO71_RS00395	COG2188	Transcriptional regulator
OIO71_RS00425	COG0010	Belongs to the arginase family
OIO71_RS00445	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS00470	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO71_RS00480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO71_RS00485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO71_RS00570	COG0534	Mate efflux family protein
OIO71_RS00575	COG0436	Aminotransferase
OIO71_RS00580	COG2733	membrane
OIO71_RS00595	COG2918	glutathione biosynthetic process
OIO71_RS00620	COG3150	esterase
OIO71_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO71_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO71_RS00650	COG2233	PERMEase
OIO71_RS00655	COG2351	hydroxyisourate hydrolase activity
OIO71_RS00690	COG3706	GGDEF domain
OIO71_RS00705	COG1393	Belongs to the ArsC family
OIO71_RS00710	COG0708	Exodeoxyribonuclease III
OIO71_RS00730	COG0189	ligase activity
OIO71_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO71_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO71_RS00775	COG4942	peptidase
OIO71_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO71_RS00795	COG2119	membrane
OIO71_RS00800	COG4774	siderophore transport
OIO71_RS00805	COG0426	domain, Protein
OIO71_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO71_RS00855	COG1902	pentaerythritol trinitrate reductase activity
OIO71_RS00860	COG1519	Transferase
OIO71_RS00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO71_RS00870	COG0668	transmembrane transport
OIO71_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO71_RS00885	COG1335	isochorismatase
OIO71_RS00890	COG1522	sequence-specific DNA binding
OIO71_RS00915	COG2205	protein histidine kinase activity
OIO71_RS00915	COG2198	Histidine kinase
OIO71_RS00915	COG0784	Response regulator, receiver
OIO71_RS00920	COG3162	membrane
OIO71_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO71_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO71_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO71_RS00960	COG1309	transcriptional regulator
OIO71_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO71_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
OIO71_RS00980	COG0351	phosphomethylpyrimidine kinase
OIO71_RS00990	COG2814	Major facilitator Superfamily
OIO71_RS01030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO71_RS01040	COG1113	amino acid transport
OIO71_RS01050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO71_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS01065	COG1335	isochorismatase
OIO71_RS01100	COG2814	Major facilitator Superfamily
OIO71_RS01105	COG0583	DNA-binding transcription factor activity
OIO71_RS01120	COG1309	transcriptional regulator
OIO71_RS01140	COG0667	Aldo Keto reductase
OIO71_RS01175	COG1733	regulation of RNA biosynthetic process
OIO71_RS01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO71_RS01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO71_RS01260	COG2329	Antibiotic biosynthesis monooxygenase
OIO71_RS01275	COG1132	(ABC) transporter
OIO71_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO71_RS01325	COG0427	acetyl-CoA hydrolase
OIO71_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO71_RS01355	COG4221	oxidoreductase activity
OIO71_RS01360	COG2873	o-acetylhomoserine
OIO71_RS01365	COG0488	(ABC) transporter
OIO71_RS01430	COG0833	amino acid
OIO71_RS01475	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO71_RS01480	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO71_RS01495	COG2226	methyltransferase
OIO71_RS01545	COG0067	glutamate synthase
OIO71_RS01545	COG0069	glutamate synthase activity
OIO71_RS01545	COG0070	glutamate synthase
OIO71_RS01550	COG0493	'glutamate synthase
OIO71_RS01560	COG1704	LemA family
OIO71_RS01565	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO71_RS01580	COG3307	-O-antigen
OIO71_RS01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO71_RS01615	COG0194	GDP metabolic process
OIO71_RS01670	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO71_RS01690	COG5380	lipid catabolic process
OIO71_RS01695	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO71_RS01720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO71_RS01725	COG0277	FAD linked oxidase domain protein
OIO71_RS01735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO71_RS01740	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO71_RS01755	COG1289	transmembrane transporter activity
OIO71_RS01765	COG0628	permease
OIO71_RS01770	COG1192	Involved in chromosome partitioning
OIO71_RS01800	COG0833	amino acid
OIO71_RS01805	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO71_RS01810	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO71_RS01820	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS01860	COG0583	DNA-binding transcription factor activity
OIO71_RS01885	COG0752	glycyl-tRNA synthetase alpha subunit
OIO71_RS01910	COG0517	IMP dehydrogenase activity
OIO71_RS01915	COG1983	PspC domain protein
OIO71_RS01925	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS01940	COG0408	coproporphyrinogen oxidase activity
OIO71_RS01960	COG0513	Belongs to the DEAD box helicase family
OIO71_RS01970	COG1127	ABC transporter
OIO71_RS01975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO71_RS01985	COG2854	intermembrane phospholipid transfer
OIO71_RS01995	COG0598	Magnesium transport protein CorA
OIO71_RS02005	COG0494	nUDIX hydrolase
OIO71_RS02010	COG1040	competence protein
OIO71_RS02015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO71_RS02035	COG1946	Acyl-CoA thioesterase
OIO71_RS02040	COG1301	dicarboxylic acid transport
OIO71_RS02055	COG1959	2 iron, 2 sulfur cluster binding
OIO71_RS02060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS02060	COG1017	nitric oxide dioxygenase activity
OIO71_RS02225	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS02230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO71_RS02260	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO71_RS02265	COG0339	signal peptide processing
OIO71_RS02270	COG0557	exoribonuclease II activity
OIO71_RS02310	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO71_RS02315	COG2169	Transcriptional regulator
OIO71_RS02320	COG0697	spore germination
OIO71_RS02325	COG1295	ribonuclease BN
OIO71_RS02360	COG1702	phosphate starvation-inducible protein PhoH
OIO71_RS02370	COG0739	heme binding
OIO71_RS02370	COG0741	lytic transglycosylase activity
OIO71_RS02370	COG1196	nuclear chromosome segregation
OIO71_RS02400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO71_RS02405	COG1183	phosphatidylcholine synthase activity
OIO71_RS02450	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS02455	COG1309	transcriptional regulator
OIO71_RS02470	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO71_RS02475	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS02495	COG2969	positive regulation of protein catabolic process
OIO71_RS02505	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO71_RS02515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO71_RS02520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO71_RS02525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO71_RS02545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO71_RS02555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO71_RS02560	COG1408	metallophosphoesterase
OIO71_RS02570	COG2199	diguanylate cyclase activity
OIO71_RS02630	COG1607	acyl-coa hydrolase
OIO71_RS02660	COG2350	Protein conserved in bacteria
OIO71_RS02670	COG0613	PHP domain protein
OIO71_RS02675	COG3781	membrane
OIO71_RS02685	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO71_RS02690	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO71_RS02700	COG1862	Preprotein translocase
OIO71_RS02730	COG2205	protein histidine kinase activity
OIO71_RS02735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO71_RS02755	COG0726	polysaccharide deacetylase
OIO71_RS02760	COG0463	Glycosyl transferase, family 2
OIO71_RS02765	COG0438	transferase activity, transferring glycosyl groups
OIO71_RS02830	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS02835	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS02845	COG2205	protein histidine kinase activity
OIO71_RS02850	COG0745	RESPONSE REGULATOR receiver
OIO71_RS02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO71_RS02870	COG0584	glycerophosphoryl diester phosphodiesterase
OIO71_RS02875	COG2096	Adenosyltransferase
OIO71_RS02925	COG0285	dihydrofolate synthase activity
OIO71_RS02945	COG0450	alkyl hydroperoxide reductase
OIO71_RS02960	COG0477	Major facilitator Superfamily
OIO71_RS02965	COG1272	protein, Hemolysin III
OIO71_RS02995	COG0183	Belongs to the thiolase family
OIO71_RS03000	COG2207	Transcriptional regulator
OIO71_RS03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO71_RS03040	COG0183	Belongs to the thiolase family
OIO71_RS03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO71_RS03050	COG2885	chlorophyll binding
OIO71_RS03060	COG1690	Belongs to the RtcB family
OIO71_RS03065	COG0833	amino acid
OIO71_RS03075	COG2233	PERMEase
OIO71_RS03080	COG1217	gtp-binding protein TYPA
OIO71_RS03105	COG2094	Belongs to the DNA glycosylase MPG family
OIO71_RS03110	COG4772	TonB-dependent receptor
OIO71_RS03115	COG1902	pentaerythritol trinitrate reductase activity
OIO71_RS03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO71_RS03135	COG0354	folic acid binding
OIO71_RS03145	COG3189	MarR family transcriptional regulator
OIO71_RS03150	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO71_RS03155	COG3422	double-strand break repair
OIO71_RS03195	COG0840	transmembrane signaling receptor activity
OIO71_RS03220	COG5510	response to toxic substance
OIO71_RS03230	COG2832	Protein of unknown function (DUF454)
OIO71_RS03235	COG1376	ErfK ybiS ycfS ynhG family protein
OIO71_RS03285	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO71_RS03295	COG1289	transmembrane transporter activity
OIO71_RS03300	COG2814	Major facilitator Superfamily
OIO71_RS03320	COG1115	amino acid carrier protein
OIO71_RS03325	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO71_RS03330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO71_RS03335	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO71_RS03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO71_RS03370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO71_RS03375	COG1077	Cell shape determining protein MreB Mrl
OIO71_RS03380	COG1792	Involved in formation and maintenance of cell shape
OIO71_RS03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO71_RS03390	COG0424	maF-like protein
OIO71_RS03395	COG1530	ribonuclease E activity
OIO71_RS03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO71_RS03415	COG0560	Phosphoserine phosphatase
OIO71_RS03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO71_RS03450	COG2207	Transcriptional regulator
OIO71_RS03495	COG1113	amino acid transport
OIO71_RS03500	COG2828	Protein conserved in bacteria
OIO71_RS03505	COG0142	geranyltranstransferase activity
OIO71_RS03510	COG2315	Protein conserved in bacteria
OIO71_RS03525	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO71_RS03545	COG2194	sulfuric ester hydrolase activity
OIO71_RS03550	COG0745	RESPONSE REGULATOR receiver
OIO71_RS03555	COG0642	Histidine kinase
OIO71_RS03570	COG0004	ammonium transporteR
OIO71_RS03575	COG0583	DNA-binding transcription factor activity
OIO71_RS03595	COG0525	valine-tRNA ligase activity
OIO71_RS03605	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS03615	COG0393	Putative heavy-metal-binding
OIO71_RS03620	COG0393	Putative heavy-metal-binding
OIO71_RS03625	COG1538	Outer membrane efflux protein
OIO71_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS03670	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO71_RS03685	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO71_RS03685	COG1648	precorrin-2 dehydrogenase activity
OIO71_RS03690	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO71_RS03695	COG1733	regulation of RNA biosynthetic process
OIO71_RS03705	COG0531	amino acid
OIO71_RS03720	COG0321	lipoyl(octanoyl) transferase activity
OIO71_RS03725	COG2921	Belongs to the UPF0250 family
OIO71_RS03760	COG2009	succinate dehydrogenase
OIO71_RS03765	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO71_RS03770	COG1053	succinate dehydrogenase
OIO71_RS03775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO71_RS03800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO71_RS03820	COG2354	Protein conserved in bacteria
OIO71_RS03825	COG2321	neutral zinc metallopeptidase
OIO71_RS03845	COG2843	Capsule synthesis protein
OIO71_RS03860	COG0589	response to stress
OIO71_RS03880	COG0505	Belongs to the CarA family
OIO71_RS03905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO71_RS03910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO71_RS03960	COG0477	Major facilitator Superfamily
OIO71_RS03965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO71_RS03980	COG1597	lipid kinase activity
OIO71_RS03985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO71_RS04010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO71_RS04015	COG0584	glycerophosphoryl diester phosphodiesterase
OIO71_RS04035	COG0741	lytic transglycosylase activity
OIO71_RS04055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO71_RS04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO71_RS04095	COG3811	Belongs to the UPF0386 family
OIO71_RS04120	COG0778	Nitroreductase
OIO71_RS04135	COG1929	Belongs to the glycerate kinase type-1 family
OIO71_RS04140	COG0243	molybdopterin cofactor binding
OIO71_RS04145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO71_RS04150	COG3339	Conserved Protein
OIO71_RS04160	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO71_RS04175	COG1113	amino acid transport
OIO71_RS04185	COG0019	diaminopimelate decarboxylase activity
OIO71_RS04195	COG2267	carboxylic ester hydrolase activity
OIO71_RS04200	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS04205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO71_RS04235	COG0463	Glycosyl transferase, family 2
OIO71_RS04255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS04290	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO71_RS04295	COG1136	(ABC) transporter
OIO71_RS04300	COG0658	competence protein
OIO71_RS04300	COG2333	competence protein COMEC
OIO71_RS04310	COG0616	signal peptide processing
OIO71_RS04310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO71_RS04315	COG0596	Alpha beta hydrolase
OIO71_RS04320	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO71_RS04330	COG0628	permease
OIO71_RS04365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO71_RS04385	COG0823	Involved in the tonB-independent uptake of proteins
OIO71_RS04405	COG0824	Thioesterase
OIO71_RS04410	COG1473	amidohydrolase
OIO71_RS04430	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO71_RS04430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO71_RS04435	COG2814	Major facilitator Superfamily
OIO71_RS04450	COG1024	Enoyl-CoA hydratase
OIO71_RS04455	COG1056	cytidyltransferase-related domain
OIO71_RS04455	COG1051	belongs to the nudix hydrolase family
OIO71_RS04465	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO71_RS04480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO71_RS04495	COG4625	pathogenesis
OIO71_RS04500	COG0583	DNA-binding transcription factor activity
OIO71_RS04505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO71_RS04510	COG4208	sulfate ABC transporter
OIO71_RS04515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO71_RS04525	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO71_RS04530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO71_RS04535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO71_RS04555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO71_RS04565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO71_RS04575	COG0681	Belongs to the peptidase S26 family
OIO71_RS04590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO71_RS04600	COG1381	Involved in DNA repair and RecF pathway recombination
OIO71_RS04605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO71_RS04615	COG4221	oxidoreductase activity
OIO71_RS04645	COG0443	Heat shock 70 kDa protein
OIO71_RS04655	COG0436	Aminotransferase
OIO71_RS04675	COG0556	nucleotide-excision repair
OIO71_RS04730	COG2070	2-Nitropropane dioxygenase
OIO71_RS04745	COG1252	NADH dehydrogenase
OIO71_RS04750	COG1686	Belongs to the peptidase S11 family
OIO71_RS04765	COG1187	pseudouridine synthase activity
OIO71_RS04965	COG4695	Portal protein
OIO71_RS05100	COG0582	viral genome integration into host DNA
OIO71_RS05125	COG0477	Major facilitator Superfamily
OIO71_RS05130	COG0583	DNA-binding transcription factor activity
OIO71_RS05135	COG1823	symporter activity
OIO71_RS05145	COG0612	Peptidase, M16
OIO71_RS05170	COG0352	thiamine-phosphate diphosphorylase activity
OIO71_RS05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS05220	COG1309	transcriptional regulator
OIO71_RS05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO71_RS05235	COG0076	glutamate decarboxylase activity
OIO71_RS05245	COG1522	sequence-specific DNA binding
OIO71_RS05250	COG3961	Belongs to the TPP enzyme family
OIO71_RS05255	COG1113	amino acid transport
OIO71_RS05260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO71_RS05265	COG0573	inorganic phosphate transmembrane transporter activity
OIO71_RS05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO71_RS05280	COG0616	signal peptide processing
OIO71_RS05315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO71_RS05320	COG1686	Belongs to the peptidase S11 family
OIO71_RS05345	COG0583	DNA-binding transcription factor activity
OIO71_RS05350	COG1067	ATP-dependent peptidase activity
OIO71_RS05375	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO71_RS05395	COG1966	Carbon starvation protein
OIO71_RS05400	COG2879	small protein
OIO71_RS05440	COG1335	isochorismatase
OIO71_RS05445	COG0583	DNA-binding transcription factor activity
OIO71_RS05460	COG0596	Alpha beta hydrolase
OIO71_RS05470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO71_RS05480	COG2130	NADP-dependent
OIO71_RS05510	COG1741	Belongs to the pirin family
OIO71_RS05520	COG2964	Protein conserved in bacteria
OIO71_RS05535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO71_RS05545	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO71_RS05550	COG4605	iron ion homeostasis
OIO71_RS05555	COG4604	ABC transporter, ATP-binding protein
OIO71_RS05560	COG4607	ABC-type enterochelin transport system periplasmic component
OIO71_RS05565	COG4774	siderophore transport
OIO71_RS05575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO71_RS05580	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO71_RS05585	COG1535	isochorismatase
OIO71_RS05585	COG3433	isochorismatase activity
OIO71_RS05600	COG1132	(ABC) transporter
OIO71_RS05605	COG1132	(ABC) transporter
OIO71_RS05610	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO71_RS05615	COG2977	Belongs to the P-Pant transferase superfamily
OIO71_RS05635	COG3739	integral membrane protein
OIO71_RS05655	COG0302	gtp cyclohydrolase
OIO71_RS05665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO71_RS05695	COG0308	aminopeptidase N
OIO71_RS05700	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO71_RS05715	COG0174	glutamine synthetase
OIO71_RS05725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO71_RS05760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO71_RS05765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO71_RS05770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO71_RS05790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO71_RS05795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO71_RS05800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO71_RS05815	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS05820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO71_RS05825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO71_RS05835	COG2223	nitrite transmembrane transporter activity
OIO71_RS05855	COG0024	Methionine aminopeptidase
OIO71_RS05860	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO71_RS05875	COG2207	Transcriptional regulator
OIO71_RS05900	COG2951	lytic endotransglycosylase activity
OIO71_RS05905	COG0772	Belongs to the SEDS family
OIO71_RS05920	COG0842	Transport permease protein
OIO71_RS05925	COG1131	(ABC) transporter
OIO71_RS05970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS05985	COG4215	(ABC) transporter
OIO71_RS05990	COG4160	amino acid transport
OIO71_RS05995	COG4598	ABC transporter
OIO71_RS06005	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO71_RS06010	COG0826	peptidase U32
OIO71_RS06015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO71_RS06030	COG1720	tRNA m6t6A37 methyltransferase activity
OIO71_RS06040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO71_RS06055	COG0642	Histidine kinase
OIO71_RS06065	COG0494	nUDIX hydrolase
OIO71_RS06075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO71_RS06080	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO71_RS06085	COG3139	Protein of unknown function (DUF1315)
OIO71_RS06095	COG1301	dicarboxylic acid transport
OIO71_RS06100	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS06105	COG2819	hydrolase of the alpha beta superfamily
OIO71_RS06115	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO71_RS06125	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO71_RS06145	COG1690	Belongs to the RtcB family
OIO71_RS06150	COG1234	tRNA 3'-trailer cleavage
OIO71_RS06155	COG4650	regulator
OIO71_RS06185	COG2363	Small membrane protein
OIO71_RS06210	COG0513	Belongs to the DEAD box helicase family
OIO71_RS06220	COG0778	Nitroreductase
OIO71_RS06250	COG1286	toxin biosynthetic process
OIO71_RS06275	COG4783	chaperone-mediated protein folding
OIO71_RS06280	COG1610	YqeY-like protein
OIO71_RS06310	COG0515	serine threonine protein kinase
OIO71_RS06310	COG2815	serine threonine protein kinase
OIO71_RS06380	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO71_RS06405	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO71_RS06410	COG0786	glutamate:sodium symporter activity
OIO71_RS06420	COG2186	Transcriptional regulator
OIO71_RS06430	COG0477	Major facilitator Superfamily
OIO71_RS06460	COG2995	paraquat-inducible protein a
OIO71_RS06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO71_RS06465	COG3008	intermembrane lipid transfer
OIO71_RS06475	COG1794	racemase activity, acting on amino acids and derivatives
OIO71_RS06505	COG1301	dicarboxylic acid transport
OIO71_RS06515	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO71_RS06520	COG2011	ABC-type metal ion transport system permease component
OIO71_RS06525	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO71_RS06530	COG1464	Belongs to the NlpA lipoprotein family
OIO71_RS06535	COG0151	Belongs to the GarS family
OIO71_RS06540	COG0138	bifunctional purine biosynthesis protein purh
OIO71_RS06545	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO71_RS06575	COG2308	Evidence 4 Homologs of previously reported genes of
OIO71_RS06585	COG1305	Transglutaminase-like
OIO71_RS06595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO71_RS06600	COG0305	Participates in initiation and elongation during chromosome replication
OIO71_RS06625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO71_RS06635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO71_RS06640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO71_RS06665	COG1649	PFAM Uncharacterised BCR, COG1649
OIO71_RS06665	COG0726	polysaccharide deacetylase
OIO71_RS06670	COG1215	transferase activity, transferring glycosyl groups
OIO71_RS06675	COG3658	cytochrome
OIO71_RS06685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO71_RS06700	COG0583	DNA-binding transcription factor activity
OIO71_RS06720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO71_RS06725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO71_RS06740	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS06745	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO71_RS06750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS06765	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OIO71_RS06775	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO71_RS06780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO71_RS06795	COG0745	RESPONSE REGULATOR receiver
OIO71_RS06800	COG0174	glutamine synthetase
OIO71_RS06820	COG0729	surface antigen
OIO71_RS06845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO71_RS06850	COG2814	Major facilitator Superfamily
OIO71_RS06865	COG0583	DNA-binding transcription factor activity
OIO71_RS06880	COG1187	pseudouridine synthase activity
OIO71_RS06900	COG0802	atpase or kinase
OIO71_RS06905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO71_RS06915	COG1923	regulation of RNA biosynthetic process
OIO71_RS06920	COG0697	spore germination
OIO71_RS06945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO71_RS06950	COG0519	Catalyzes the synthesis of GMP from XMP
OIO71_RS06950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO71_RS06955	COG4302	ethanolamine ammonia-lyase activity
OIO71_RS06960	COG4303	Ethanolamine ammonia lyase large subunit
OIO71_RS06965	COG0531	amino acid
OIO71_RS06985	COG1454	alcohol dehydrogenase
OIO71_RS06990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO71_RS07000	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO71_RS07020	COG0308	aminopeptidase N
OIO71_RS07040	COG1605	Chorismate mutase
OIO71_RS07060	COG1309	transcriptional regulator
OIO71_RS07070	COG0668	transmembrane transport
OIO71_RS07120	COG0488	(ABC) transporter
OIO71_RS07125	COG0589	response to stress
OIO71_RS07150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO71_RS07160	COG3135	benzoate transporter
OIO71_RS07165	COG1522	sequence-specific DNA binding
OIO71_RS07175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO71_RS07180	COG0583	DNA-binding transcription factor activity
OIO71_RS07190	COG0183	Belongs to the thiolase family
OIO71_RS07200	COG2030	dehydratase
OIO71_RS07205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO71_RS07230	COG0824	Thioesterase
OIO71_RS07235	COG1454	alcohol dehydrogenase
OIO71_RS07245	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO71_RS07265	COG0069	glutamate synthase activity
OIO71_RS07285	COG2814	Major facilitator Superfamily
OIO71_RS07300	COG0511	ligase activity, forming carbon-carbon bonds
OIO71_RS07320	COG1116	anion transmembrane transporter activity
OIO71_RS07320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO71_RS07325	COG0745	RESPONSE REGULATOR receiver
OIO71_RS07335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO71_RS07335	COG2146	nitrite reductase [NAD(P)H] activity
OIO71_RS07340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO71_RS07345	COG0243	molybdopterin cofactor binding
OIO71_RS07355	COG0243	molybdopterin cofactor binding
OIO71_RS07375	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO71_RS07375	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO71_RS07390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO71_RS07395	COG0697	spore germination
OIO71_RS07415	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO71_RS07420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO71_RS07475	COG2204	response regulator
OIO71_RS07480	COG3852	Histidine kinase
OIO71_RS07500	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO71_RS07505	COG0575	Belongs to the CDS family
OIO71_RS07520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO71_RS07540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO71_RS07555	COG2137	regulation of response to DNA damage stimulus
OIO71_RS07565	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO71_RS07570	COG1011	Hydrolase
OIO71_RS07595	COG1522	sequence-specific DNA binding
OIO71_RS07605	COG1113	amino acid transport
OIO71_RS07625	COG0659	secondary active sulfate transmembrane transporter activity
OIO71_RS07630	COG2135	peptidase activity
OIO71_RS07645	COG3300	MHYT domain
OIO71_RS07645	COG5001	Diguanylate cyclase
OIO71_RS07665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO71_RS07665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO71_RS07665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO71_RS07670	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO71_RS07675	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO71_RS07675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO71_RS07705	COG0024	Methionine aminopeptidase
OIO71_RS07710	COG0583	DNA-binding transcription factor activity
OIO71_RS07720	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO71_RS07725	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO71_RS07730	COG0517	IMP dehydrogenase activity
OIO71_RS07730	COG0516	GMP reductase activity
OIO71_RS07755	COG0552	protein localization to endoplasmic reticulum
OIO71_RS07765	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO71_RS07775	COG4890	Cyd operon protein YbgT
OIO71_RS07780	COG1294	oxidase, subunit
OIO71_RS07795	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO71_RS07805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO71_RS07810	COG4774	siderophore transport
OIO71_RS07825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO71_RS07830	COG0569	domain protein
OIO71_RS07835	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO71_RS07865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO71_RS07870	COG0542	response to heat
OIO71_RS07880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO71_RS07895	COG1902	pentaerythritol trinitrate reductase activity
OIO71_RS07895	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO71_RS07940	COG2323	membrane
OIO71_RS07945	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO71_RS07955	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO71_RS07960	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO71_RS07965	COG0183	Belongs to the thiolase family
OIO71_RS07970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO71_RS07975	COG0596	Alpha beta hydrolase
OIO71_RS07980	COG2271	Major facilitator Superfamily
OIO71_RS07985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO71_RS07990	COG3485	protocatechuate 3,4-dioxygenase
OIO71_RS07995	COG3485	protocatechuate 3,4-dioxygenase
OIO71_RS08000	COG0710	3-dehydroquinate dehydratase activity
OIO71_RS08005	COG3420	alginic acid biosynthetic process
OIO71_RS08010	COG3659	wide pore channel activity
OIO71_RS08015	COG4993	Dehydrogenase
OIO71_RS08025	COG2391	methyltransferase activity
OIO71_RS08040	COG1414	Transcriptional regulator
OIO71_RS08045	COG0583	DNA-binding transcription factor activity
OIO71_RS08050	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS08075	COG2814	Major facilitator Superfamily
OIO71_RS08085	COG0154	amidase activity
OIO71_RS08105	COG4638	Rieske (2fe-2S)
OIO71_RS08115	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS08125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS08135	COG3733	amine oxidase
OIO71_RS08145	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO71_RS08160	COG0183	Belongs to the thiolase family
OIO71_RS08165	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO71_RS08170	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO71_RS08180	COG4829	muconolactone delta-isomerase
OIO71_RS08185	COG4948	Mandelate Racemase Muconate Lactonizing
OIO71_RS08190	COG0583	DNA-binding transcription factor activity
OIO71_RS08200	COG2186	Transcriptional regulator
OIO71_RS08220	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08225	COG3231	kanamycin kinase activity
OIO71_RS08240	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS08245	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS08250	COG3829	transcription factor binding
OIO71_RS08260	COG3162	membrane
OIO71_RS08275	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08290	COG0753	catalase activity
OIO71_RS08315	COG1846	Transcriptional regulator
OIO71_RS08320	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO71_RS08320	COG1902	pentaerythritol trinitrate reductase activity
OIO71_RS08355	COG1309	transcriptional regulator
OIO71_RS08365	COG1335	isochorismatase
OIO71_RS08370	COG0583	DNA-binding transcription factor activity
OIO71_RS08380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO71_RS08380	COG0475	glutathione-regulated potassium exporter activity
OIO71_RS08390	COG1473	amidohydrolase
OIO71_RS08445	COG2188	Transcriptional regulator
OIO71_RS08460	COG0583	DNA-binding transcription factor activity
OIO71_RS08495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO71_RS08515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO71_RS08535	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08550	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO71_RS08555	COG2814	Major facilitator Superfamily
OIO71_RS08565	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO71_RS08575	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08580	COG3384	dioxygenase
OIO71_RS08590	COG3971	2-oxopent-4-enoate hydratase activity
OIO71_RS08605	COG0477	Major facilitator Superfamily
OIO71_RS08610	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS08615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS08620	COG1846	Transcriptional regulator
OIO71_RS08625	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS08630	COG0129	dihydroxy-acid dehydratase activity
OIO71_RS08640	COG0583	DNA-binding transcription factor activity
OIO71_RS08645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO71_RS08655	COG2084	Dehydrogenase
OIO71_RS08660	COG2207	Transcriptional regulator
OIO71_RS08675	COG1064	alcohol dehydrogenase
OIO71_RS08685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO71_RS08690	COG1120	ATPase activity
OIO71_RS08710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO71_RS08760	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO71_RS08785	COG2814	Major facilitator Superfamily
OIO71_RS08790	COG3320	Male sterility
OIO71_RS08790	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO71_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS08830	COG2207	Transcriptional regulator
OIO71_RS08840	COG2205	protein histidine kinase activity
OIO71_RS08845	COG0745	RESPONSE REGULATOR receiver
OIO71_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS08855	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO71_RS08880	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO71_RS08890	COG0753	catalase activity
OIO71_RS08910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO71_RS08970	COG1535	isochorismatase
OIO71_RS08970	COG3433	isochorismatase activity
OIO71_RS08975	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS08980	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO71_RS08985	COG4149	molybdate abc transporter
OIO71_RS08990	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO71_RS09000	COG4638	Rieske (2fe-2S)
OIO71_RS09005	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO71_RS09010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS09010	COG0543	2 iron, 2 sulfur cluster binding
OIO71_RS09025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS09050	COG2207	Transcriptional regulator
OIO71_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS09060	COG2610	gluconate transmembrane transporter activity
OIO71_RS09070	COG0583	DNA-binding transcription factor activity
OIO71_RS09085	COG2031	fatty acid transporter
OIO71_RS09090	COG0183	Belongs to the thiolase family
OIO71_RS09095	COG0583	DNA-binding transcription factor activity
OIO71_RS09100	COG0583	DNA-binding transcription factor activity
OIO71_RS09115	COG1027	Aspartate ammonia-lyase
OIO71_RS09125	COG0477	Major facilitator Superfamily
OIO71_RS09145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO71_RS09150	COG4521	taurine ABC transporter
OIO71_RS09165	COG2188	Transcriptional regulator
OIO71_RS09175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO71_RS09180	COG1733	regulation of RNA biosynthetic process
OIO71_RS09185	COG3708	Transcriptional regulator
OIO71_RS09185	COG2207	Transcriptional regulator
OIO71_RS09200	COG0730	response to heat
OIO71_RS09215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO71_RS09215	COG3453	Protein conserved in bacteria
OIO71_RS09225	COG3781	membrane
OIO71_RS09230	COG1063	alcohol dehydrogenase
OIO71_RS09240	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO71_RS09245	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO71_RS09250	COG0022	dehydrogenase e1 component
OIO71_RS09255	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO71_RS09260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO71_RS09275	COG3706	GGDEF domain
OIO71_RS09290	COG0133	tryptophan synthase activity
OIO71_RS09300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO71_RS09335	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO71_RS09360	COG2226	methyltransferase
OIO71_RS09415	COG0842	Transport permease protein
OIO71_RS09420	COG0842	Transport permease protein
OIO71_RS09425	COG1131	(ABC) transporter
OIO71_RS09440	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO71_RS09465	COG0730	response to heat
OIO71_RS09470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO71_RS09485	COG0406	alpha-ribazole phosphatase activity
OIO71_RS09490	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO71_RS09505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO71_RS09535	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO71_RS09545	COG4264	IucA IucC family
OIO71_RS09550	COG4264	IucA IucC family
OIO71_RS09555	COG2814	Major facilitator Superfamily
OIO71_RS09570	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO71_RS09585	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS09590	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS09595	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO71_RS09600	COG2207	Transcriptional regulator
OIO71_RS09605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO71_RS09610	COG0776	regulation of translation
OIO71_RS09635	COG0822	iron-sulfur transferase activity
OIO71_RS09640	COG0316	Belongs to the HesB IscA family
OIO71_RS09670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO71_RS09690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO71_RS09695	COG0702	epimerase
OIO71_RS09730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO71_RS09740	COG0339	signal peptide processing
OIO71_RS09750	COG4166	transmembrane transport
OIO71_RS09785	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO71_RS09790	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO71_RS09820	COG0776	regulation of translation
OIO71_RS09885	COG0084	hydrolase, TatD family'
OIO71_RS09905	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO71_RS09910	COG1132	(ABC) transporter
OIO71_RS09920	COG0811	peptide transport
OIO71_RS09925	COG1475	DNA binding
OIO71_RS09930	COG1192	Involved in chromosome partitioning
OIO71_RS09940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO71_RS09955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO71_RS09960	COG0191	fructose-bisphosphate aldolase activity
OIO71_RS09980	COG0424	maF-like protein
OIO71_RS09985	COG2850	peptidyl-arginine hydroxylation
OIO71_RS09995	COG0640	Transcriptional regulator
OIO71_RS10005	COG3619	membrane
OIO71_RS10010	COG3122	Protein conserved in bacteria
OIO71_RS10015	COG1132	(ABC) transporter
OIO71_RS10035	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO71_RS10040	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO71_RS10050	COG0506	proline dehydrogenase activity
OIO71_RS10050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO71_RS10050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO71_RS10055	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO71_RS10070	COG3698	Phosphodiester glycosidase
OIO71_RS10080	COG2353	YceI-like domain
OIO71_RS10090	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO71_RS10135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO71_RS10135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO71_RS10160	COG3539	Fimbrial protein
OIO71_RS10165	COG3121	Chaperone
OIO71_RS10190	COG0697	spore germination
OIO71_RS10200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO71_RS10210	COG0583	DNA-binding transcription factor activity
OIO71_RS10230	COG1309	transcriptional regulator
OIO71_RS10245	COG1522	sequence-specific DNA binding
OIO71_RS10255	COG1126	abc transporter atp-binding protein
OIO71_RS10260	COG0765	amino acid transport
OIO71_RS10265	COG0765	amino acid transport
OIO71_RS10295	COG1464	Belongs to the NlpA lipoprotein family
OIO71_RS10305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO71_RS10310	COG2011	ABC-type metal ion transport system permease component
OIO71_RS10315	COG0012	GTP binding
OIO71_RS10340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO71_RS10380	COG0386	Belongs to the glutathione peroxidase family
OIO71_RS10390	COG0436	Aminotransferase
OIO71_RS10395	COG1301	dicarboxylic acid transport
OIO71_RS10430	COG3634	alkyl hydroperoxide reductase activity
OIO71_RS10445	COG0583	DNA-binding transcription factor activity
OIO71_RS10450	COG0798	PFAM Bile acid sodium symporter
OIO71_RS10455	COG0640	Transcriptional regulator
OIO71_RS10470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO71_RS10480	COG0583	DNA-binding transcription factor activity
OIO71_RS10490	COG1953	Uracil, thiamine, allantoin
OIO71_RS10500	COG2175	clavaminate synthase activity
OIO71_RS10505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO71_RS10525	COG4521	taurine ABC transporter
OIO71_RS10535	COG0477	Major facilitator Superfamily
OIO71_RS10555	COG1271	oxidase subunit
OIO71_RS10560	COG1294	oxidase, subunit
OIO71_RS10570	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO71_RS10590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO71_RS10610	COG3052	prosthetic group binding
OIO71_RS10615	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO71_RS10625	COG0583	DNA-binding transcription factor activity
OIO71_RS10635	COG2814	Major facilitator Superfamily
OIO71_RS10655	COG1346	cytolysis
OIO71_RS10665	COG0583	DNA-binding transcription factor activity
OIO71_RS10670	COG0625	glutathione transferase activity
OIO71_RS10675	COG0625	glutathione transferase activity
OIO71_RS10680	COG0583	DNA-binding transcription factor activity
OIO71_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS10695	COG1045	serine acetyltransferase
OIO71_RS10700	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO71_RS10705	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO71_RS10715	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS10730	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO71_RS10735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO71_RS10740	COG1126	abc transporter atp-binding protein
OIO71_RS10745	COG0765	amino acid transport
OIO71_RS10750	COG0765	amino acid transport
OIO71_RS10770	COG2205	protein histidine kinase activity
OIO71_RS10770	COG0784	Response regulator, receiver
OIO71_RS10790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO71_RS10810	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS10860	COG0583	DNA-binding transcription factor activity
OIO71_RS10880	COG0318	PFAM AMP-dependent synthetase and ligase
OIO71_RS10885	COG1309	transcriptional regulator
OIO71_RS10890	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS10895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO71_RS10900	COG1024	Enoyl-CoA hydratase
OIO71_RS10905	COG4770	biotin carboxylase activity
OIO71_RS10915	COG0583	DNA-binding transcription factor activity
OIO71_RS10935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO71_RS10955	COG3842	ATPase activity
OIO71_RS10960	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO71_RS10975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO71_RS10980	COG1414	Transcriptional regulator
OIO71_RS10990	COG0583	DNA-binding transcription factor activity
OIO71_RS10995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO71_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS11010	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO71_RS11020	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS11025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO71_RS11030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS11035	COG2267	carboxylic ester hydrolase activity
OIO71_RS11055	COG3038	cytochrome b561
OIO71_RS11060	COG0753	catalase activity
OIO71_RS11065	COG2271	Major facilitator Superfamily
OIO71_RS11070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO71_RS11075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO71_RS11175	COG2207	Transcriptional regulator
OIO71_RS11185	COG1278	Cold shock
OIO71_RS11220	COG0556	nucleotide-excision repair
OIO71_RS11230	COG2050	protein possibly involved in aromatic compounds catabolism
OIO71_RS11240	COG3327	negative regulation of DNA-templated transcription, initiation
OIO71_RS11245	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO71_RS11250	COG0183	Belongs to the thiolase family
OIO71_RS11255	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO71_RS11260	COG1024	Enoyl-CoA hydratase
OIO71_RS11265	COG1024	Enoyl-CoA hydratase
OIO71_RS11270	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS11275	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO71_RS11280	COG3396	Phenylacetate-CoA oxygenase
OIO71_RS11285	COG3460	Phenylacetate-CoA oxygenase
OIO71_RS11290	COG3396	Phenylacetate-CoA oxygenase
OIO71_RS11295	COG2030	dehydratase
OIO71_RS11295	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS11300	COG1760	l-serine dehydratase
OIO71_RS11305	COG0531	amino acid
OIO71_RS11310	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS11335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OIO71_RS11355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO71_RS11365	COG0789	Transcriptional regulator
OIO71_RS11375	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OIO71_RS11390	COG2807	transmembrane transport
OIO71_RS11395	COG0590	tRNA wobble adenosine to inosine editing
OIO71_RS11520	COG1116	anion transmembrane transporter activity
OIO71_RS11525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO71_RS11535	COG0864	Transcriptional regulator
OIO71_RS11545	COG1733	regulation of RNA biosynthetic process
OIO71_RS11550	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO71_RS11555	COG0439	Biotin carboxylase
OIO71_RS11570	COG1063	alcohol dehydrogenase
OIO71_RS11580	COG1309	transcriptional regulator
OIO71_RS11620	COG0038	chloride channel
OIO71_RS11625	COG4770	biotin carboxylase activity
OIO71_RS11645	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO71_RS11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO71_RS11730	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO71_RS11735	COG1116	anion transmembrane transporter activity
OIO71_RS11740	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO71_RS11770	COG0598	Magnesium transport protein CorA
OIO71_RS11780	COG1560	Kdo2-lipid A biosynthetic process
OIO71_RS11790	COG5006	permease, DMT superfamily
OIO71_RS11795	COG1522	sequence-specific DNA binding
OIO71_RS11810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO71_RS11820	COG4122	O-methyltransferase activity
OIO71_RS11855	COG1137	ATPase activity
OIO71_RS11860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO71_RS11870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO71_RS11875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO71_RS11875	COG0517	IMP dehydrogenase activity
OIO71_RS11915	COG2814	Major facilitator Superfamily
OIO71_RS11950	COG1278	Cold shock
OIO71_RS11955	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS11985	COG1570	exodeoxyribonuclease VII activity
OIO71_RS12035	COG0583	DNA-binding transcription factor activity
OIO71_RS12045	COG4638	Rieske (2fe-2S)
OIO71_RS12055	COG0543	2 iron, 2 sulfur cluster binding
OIO71_RS12055	COG0633	Ferredoxin
OIO71_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS12065	COG3135	benzoate transporter
OIO71_RS12070	COG2814	Major facilitator Superfamily
OIO71_RS12085	COG1643	Atp-dependent helicase
OIO71_RS12090	COG0450	alkyl hydroperoxide reductase
OIO71_RS12100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO71_RS12110	COG3634	alkyl hydroperoxide reductase activity
OIO71_RS12130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO71_RS12290	COG0625	glutathione transferase activity
OIO71_RS12300	COG2885	chlorophyll binding
OIO71_RS12335	COG0542	response to heat
OIO71_RS12350	COG1765	OsmC-like protein
OIO71_RS12365	COG0667	Aldo Keto reductase
OIO71_RS12380	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO71_RS12395	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO71_RS12405	COG0527	aspartate kinase activity
OIO71_RS12415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO71_RS12425	COG3038	cytochrome b561
OIO71_RS12430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO71_RS12435	COG2252	PERMEase
OIO71_RS12445	COG2072	flavoprotein involved in K transport
OIO71_RS12460	COG1741	Belongs to the pirin family
OIO71_RS12465	COG1309	transcriptional regulator
OIO71_RS12475	COG0300	oxidoreductase activity
OIO71_RS12480	COG2072	flavoprotein involved in K transport
OIO71_RS12485	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO71_RS12530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS12550	COG2814	Major facilitator Superfamily
OIO71_RS12555	COG1024	Enoyl-CoA hydratase
OIO71_RS12560	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS12570	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS12595	COG2186	Transcriptional regulator
OIO71_RS12600	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS12610	COG4948	Mandelate Racemase Muconate Lactonizing
OIO71_RS12615	COG2271	Major facilitator Superfamily
OIO71_RS12620	COG2721	sulfolactate sulfo-lyase activity
OIO71_RS12625	COG0697	spore germination
OIO71_RS12670	COG1113	amino acid transport
OIO71_RS12690	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS12710	COG0531	amino acid
OIO71_RS12720	COG1113	amino acid transport
OIO71_RS12760	COG3209	COG3209 Rhs family protein
OIO71_RS12780	COG4269	membrane
OIO71_RS12795	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO71_RS12795	COG1902	pentaerythritol trinitrate reductase activity
OIO71_RS12805	COG4251	negative regulation of phosphorylation
OIO71_RS12805	COG5001	Diguanylate cyclase
OIO71_RS12805	COG2203	Gaf domain
OIO71_RS12805	COG3706	GGDEF domain
OIO71_RS12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO71_RS12840	COG4172	Belongs to the ABC transporter superfamily
OIO71_RS12845	COG4239	(ABC) transporter, permease
OIO71_RS12850	COG4174	ABC transporter (Permease)
OIO71_RS12860	COG0741	lytic transglycosylase activity
OIO71_RS12860	COG1388	LysM domain
OIO71_RS12860	COG0741	lytic transglycosylase activity
OIO71_RS12860	COG1388	LysM domain
OIO71_RS12865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO71_RS12905	COG0583	DNA-binding transcription factor activity
OIO71_RS12910	COG1279	arginine transmembrane transporter activity
OIO71_RS12930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO71_RS12935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO71_RS12940	COG0006	proline dipeptidase activity
OIO71_RS12975	COG2194	sulfuric ester hydrolase activity
OIO71_RS13140	COG5410	chromosome segregation
OIO71_RS13320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO71_RS13340	COG3384	dioxygenase
OIO71_RS13350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO71_RS13355	COG2878	Part of a membrane complex involved in electron transport
OIO71_RS13360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO71_RS13385	COG0768	penicillin binding
OIO71_RS13390	COG0742	ribosomal rna small subunit methyltransferase
OIO71_RS13405	COG0830	nickel cation binding
OIO71_RS13415	COG0804	urea catabolic process
OIO71_RS13455	COG1253	flavin adenine dinucleotide binding
OIO71_RS13460	COG2851	Citrate transporter
OIO71_RS13510	COG1773	rubredoxin
OIO71_RS13515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO71_RS13525	COG0583	DNA-binding transcription factor activity
OIO71_RS13555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO71_RS13560	COG4181	ATPase activity
OIO71_RS13640	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO71_RS13665	COG0306	phosphate transporter
OIO71_RS13675	COG3958	Transketolase
OIO71_RS13680	COG3959	Transketolase, thiamine diphosphate binding domain
OIO71_RS13685	COG2271	Major facilitator Superfamily
OIO71_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS13695	COG0583	DNA-binding transcription factor activity
OIO71_RS13715	COG2207	Transcriptional regulator
OIO71_RS13720	COG2066	Belongs to the glutaminase family
OIO71_RS13725	COG0242	peptide deformylase activity
OIO71_RS13730	COG0477	Major facilitator Superfamily
OIO71_RS13740	COG0028	Belongs to the TPP enzyme family
OIO71_RS13755	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS13760	COG2267	carboxylic ester hydrolase activity
OIO71_RS13770	COG2271	Major facilitator Superfamily
OIO71_RS13775	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO71_RS13785	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS13805	COG1414	Transcriptional regulator
OIO71_RS13820	COG1024	Enoyl-CoA hydratase
OIO71_RS13830	COG1215	transferase activity, transferring glycosyl groups
OIO71_RS13835	COG0726	polysaccharide deacetylase
OIO71_RS13835	COG1649	PFAM Uncharacterised BCR, COG1649
OIO71_RS13845	COG4681	YaeQ
OIO71_RS13855	COG0523	cobalamin synthesis protein
OIO71_RS13865	COG1607	acyl-coa hydrolase
OIO71_RS13875	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO71_RS13880	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO71_RS13885	COG1309	transcriptional regulator
OIO71_RS13910	COG2040	homocysteine
OIO71_RS13915	COG0531	amino acid
OIO71_RS13970	COG1595	DNA-templated transcription, initiation
OIO71_RS13980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO71_RS13985	COG0477	Major facilitator Superfamily
OIO71_RS13995	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
OIO71_RS14055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO71_RS14140	COG0592	DNA-directed DNA polymerase activity
OIO71_RS14180	COG2026	Addiction module toxin, RelE StbE family
OIO71_RS14400	COG1484	DNA-dependent DNA replication
OIO71_RS14485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO71_RS14565	COG0405	Gamma-glutamyltransferase
OIO71_RS14570	COG2814	Major facilitator Superfamily
OIO71_RS14580	COG2050	protein possibly involved in aromatic compounds catabolism
OIO71_RS14595	COG1090	epimerase
OIO71_RS14615	COG0420	3'-5' exonuclease activity
OIO71_RS14640	COG0735	belongs to the Fur family
OIO71_RS14645	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO71_RS14665	COG0121	glutamine amidotransferase
OIO71_RS14680	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO71_RS14690	COG0210	DNA helicase
OIO71_RS14695	COG2885	chlorophyll binding
OIO71_RS14700	COG0204	Acyl-transferase
OIO71_RS14715	COG2894	cell division
OIO71_RS14730	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS14735	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO71_RS14735	COG1674	ftsk spoiiie
OIO71_RS14740	COG0492	ferredoxin-NADP+ reductase activity
OIO71_RS14745	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO71_RS14755	COG0456	acetyltransferase
OIO71_RS14800	COG1981	membrane
OIO71_RS14815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO71_RS14815	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO71_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS14845	COG0657	acetylesterase activity
OIO71_RS14855	COG0473	3-isopropylmalate dehydrogenase activity
OIO71_RS14860	COG0583	DNA-binding transcription factor activity
OIO71_RS14890	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO71_RS14915	COG0564	pseudouridine synthase activity
OIO71_RS14925	COG0358	DNA primase activity
OIO71_RS14940	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO71_RS14970	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO71_RS15000	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO71_RS15010	COG0351	phosphomethylpyrimidine kinase
OIO71_RS15010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO71_RS15010	COG0352	thiamine-phosphate diphosphorylase activity
OIO71_RS15015	COG1652	LysM domain
OIO71_RS15040	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO71_RS15045	COG3101	peptidyl-lysine hydroxylation
OIO71_RS15050	COG0009	L-threonylcarbamoyladenylate synthase
OIO71_RS15055	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO71_RS15060	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO71_RS15075	COG4106	trans-aconitate 2-methyltransferase activity
OIO71_RS15090	COG0596	Alpha beta hydrolase
OIO71_RS15090	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO71_RS15090	COG2226	methyltransferase
OIO71_RS15095	COG1877	trehalose-phosphatase activity
OIO71_RS15100	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO71_RS15105	COG2223	nitrite transmembrane transporter activity
OIO71_RS15125	COG1196	nuclear chromosome segregation
OIO71_RS15135	COG0730	response to heat
OIO71_RS15150	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO71_RS15160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO71_RS15210	COG0489	protein tyrosine kinase activity
OIO71_RS15220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO71_RS15220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO71_RS15250	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO71_RS15255	COG2081	HI0933 family
OIO71_RS15265	COG0668	transmembrane transport
OIO71_RS15285	COG0583	DNA-binding transcription factor activity
OIO71_RS15310	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO71_RS15315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO71_RS15345	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO71_RS15385	COG0745	RESPONSE REGULATOR receiver
OIO71_RS15405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO71_RS15410	COG0697	spore germination
OIO71_RS15445	COG0477	Major facilitator Superfamily
OIO71_RS15455	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS15475	COG0384	phenazine biosynthesis protein PhzF
OIO71_RS15520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO71_RS15535	COG0583	DNA-binding transcription factor activity
OIO71_RS15545	COG0583	DNA-binding transcription factor activity
OIO71_RS15560	COG0583	DNA-binding transcription factor activity
OIO71_RS15565	COG1053	succinate dehydrogenase
OIO71_RS15575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO71_RS15580	COG2814	Major facilitator Superfamily
OIO71_RS15585	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS15590	COG0583	DNA-binding transcription factor activity
OIO71_RS15595	COG1063	alcohol dehydrogenase
OIO71_RS15625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO71_RS15630	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO71_RS15635	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO71_RS15655	COG2132	Multicopper oxidase
OIO71_RS15665	COG0561	phosphatase activity
OIO71_RS15670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO71_RS15680	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO71_RS15695	COG1214	PFAM Peptidase M22, glycoprotease
OIO71_RS15765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO71_RS15770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO71_RS15775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO71_RS15835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO71_RS15845	COG1846	Transcriptional regulator
OIO71_RS15850	COG1764	response to oxidative stress
OIO71_RS15900	COG0037	tRNA processing
OIO71_RS15910	COG0248	Ppx GppA phosphatase
OIO71_RS15940	COG0072	phenylalanine-tRNA ligase activity
OIO71_RS15985	COG1238	metal cluster binding
OIO71_RS15990	COG0625	glutathione transferase activity
OIO71_RS16005	COG0318	PFAM AMP-dependent synthetase and ligase
OIO71_RS16010	COG3028	Belongs to the UPF0307 family
OIO71_RS16015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO71_RS16035	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO71_RS16040	COG0617	tRNA 3'-terminal CCA addition
OIO71_RS16045	COG1555	photosystem II stabilization
OIO71_RS16050	COG3956	TIGRFAM MazG family protein
OIO71_RS16060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO71_RS16080	COG0784	Response regulator, receiver
OIO71_RS16080	COG5002	protein histidine kinase activity
OIO71_RS16080	COG2205	protein histidine kinase activity
OIO71_RS16085	COG1024	Enoyl-CoA hydratase
OIO71_RS16090	COG2084	Dehydrogenase
OIO71_RS16095	COG3622	Belongs to the hyi family
OIO71_RS16130	COG0697	spore germination
OIO71_RS16140	COG2814	Major facilitator Superfamily
OIO71_RS16150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO71_RS16220	COG4774	siderophore transport
OIO71_RS16235	COG1271	oxidase subunit
OIO71_RS16240	COG1294	oxidase, subunit
OIO71_RS16310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO71_RS16320	COG0583	DNA-binding transcription factor activity
OIO71_RS16330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO71_RS16340	COG0084	hydrolase, TatD family'
OIO71_RS16355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO71_RS16385	COG0440	acetolactate synthase activity
OIO71_RS16390	COG0028	Belongs to the TPP enzyme family
OIO71_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO71_RS16420	COG1136	(ABC) transporter
OIO71_RS16420	COG0577	efflux transmembrane transporter activity
OIO71_RS16425	COG1538	Outer membrane efflux protein
OIO71_RS16440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO71_RS16445	COG1162	GTPase activity
OIO71_RS16455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO71_RS16495	COG1426	Protein conserved in bacteria
OIO71_RS16530	COG0793	Belongs to the peptidase S41A family
OIO71_RS16545	COG2267	carboxylic ester hydrolase activity
OIO71_RS16555	COG1012	belongs to the aldehyde dehydrogenase family
OIO71_RS16560	COG3265	gluconokinase activity
OIO71_RS16570	COG0800	Aldolase
OIO71_RS16580	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO71_RS16585	COG0280	phosphate acetyltransferase
OIO71_RS16585	COG0857	belongs to the CobB CobQ family
OIO71_RS16590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO71_RS16590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO71_RS16610	COG0740	serine-type endopeptidase activity
OIO71_RS16620	COG4774	siderophore transport
OIO71_RS16630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO71_RS16640	COG2813	Specifically methylates the guanine in position
OIO71_RS16640	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO71_RS16740	COG0788	formyltetrahydrofolate deformylase activity
OIO71_RS16765	COG4651	solute:proton antiporter activity
OIO71_RS16765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO71_RS16785	COG0724	RNA recognition motif
OIO71_RS16790	COG0210	DNA helicase
OIO71_RS16815	COG1733	regulation of RNA biosynthetic process
OIO71_RS16825	COG2900	Belongs to the SlyX family
OIO71_RS16830	COG0488	(ABC) transporter
OIO71_RS16835	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS16840	COG1560	Kdo2-lipid A biosynthetic process
OIO71_RS16850	COG1301	dicarboxylic acid transport
OIO71_RS16905	COG0473	3-isopropylmalate dehydrogenase activity
OIO71_RS16960	COG0583	DNA-binding transcription factor activity
OIO71_RS16970	COG0625	glutathione transferase activity
OIO71_RS16975	COG2378	regulation of single-species biofilm formation
OIO71_RS16980	COG0546	phosphoglycolate phosphatase activity
OIO71_RS16990	COG1530	ribonuclease E activity
OIO71_RS16995	COG0318	PFAM AMP-dependent synthetase and ligase
OIO71_RS17010	COG0583	DNA-binding transcription factor activity
OIO71_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS17020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO71_RS17030	COG0534	Mate efflux family protein
OIO71_RS17045	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO71_RS17070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO71_RS17070	COG0493	'glutamate synthase
OIO71_RS17080	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO71_RS17085	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO71_RS17100	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO71_RS17110	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO71_RS17110	COG0644	oxidoreductase
OIO71_RS17120	COG0425	Belongs to the sulfur carrier protein TusA family
OIO71_RS17125	COG4535	Mg2 and Co2 transporter CorC
OIO71_RS17135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO71_RS17155	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO71_RS17160	COG0475	glutathione-regulated potassium exporter activity
OIO71_RS17160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO71_RS17175	COG0484	heat shock protein binding
OIO71_RS17180	COG0789	Transcriptional regulator
OIO71_RS17185	COG0598	Magnesium transport protein CorA
OIO71_RS17200	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO71_RS17205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO71_RS17210	COG1074	ATP-dependent DNA helicase activity
OIO71_RS17215	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO71_RS17235	COG2226	methyltransferase
OIO71_RS17255	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO71_RS17270	COG2111	Na H antiporter
OIO71_RS17270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO71_RS17275	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO71_RS17280	COG0651	ATP synthesis coupled electron transport
OIO71_RS17285	COG1863	multisubunit Na H antiporter MnhE subunit
OIO71_RS17290	COG2212	antiporter activity
OIO71_RS17295	COG1320	monovalent cation:proton antiporter activity
OIO71_RS17310	COG0195	Participates in both transcription termination and antitermination
OIO71_RS17360	COG0237	dephospho-CoA kinase activity
OIO71_RS17370	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO71_RS17385	COG0497	DNA recombination
OIO71_RS17395	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO71_RS17425	COG2169	Transcriptional regulator
OIO71_RS17425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO71_RS17430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO71_RS17490	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO71_RS17505	COG0326	Molecular chaperone. Has ATPase activity
OIO71_RS17520	COG2056	Na+-H+ antiporter family
OIO71_RS17620	COG0546	phosphoglycolate phosphatase activity
OIO71_RS17625	COG1716	ATPase activity
OIO71_RS17670	COG0181	hydroxymethylbilane synthase activity
OIO71_RS17680	COG3275	phosphorelay sensor kinase activity
OIO71_RS17700	COG1538	Outer membrane efflux protein
OIO71_RS17705	COG0697	spore germination
OIO71_RS17750	COG1061	Type III restriction enzyme res subunit
OIO71_RS17755	COG1002	Type II restriction enzyme, methylase subunits
OIO71_RS17765	COG0659	secondary active sulfate transmembrane transporter activity
OIO71_RS17770	COG0589	response to stress
OIO71_RS17815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO71_RS17820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO71_RS17825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO71_RS17830	COG0772	Belongs to the SEDS family
OIO71_RS17855	COG4974	Belongs to the 'phage' integrase family
OIO71_RS17860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO71_RS17870	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO71_RS17880	COG2197	response regulator
OIO71_RS17895	COG0793	Belongs to the peptidase S41A family
OIO71_RS17900	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO71_RS17905	COG0795	lipopolysaccharide-transporting ATPase activity
OIO71_RS17945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO71_RS17945	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO71_RS17955	COG0004	ammonium transporteR
OIO71_RS17960	COG0347	Belongs to the P(II) protein family
OIO71_RS17995	COG1061	Type III restriction enzyme res subunit
OIO71_RS18000	COG1002	Type II restriction enzyme, methylase subunits
OIO71_RS18015	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO71_RS18030	COG0318	PFAM AMP-dependent synthetase and ligase
OIO71_RS18040	COG0477	Major facilitator Superfamily
OIO71_RS18045	COG2860	membrane
OIO71_RS18055	COG1253	flavin adenine dinucleotide binding
OIO71_RS18065	COG0477	Major facilitator Superfamily
OIO71_RS18070	COG3757	hydrolase, family 25
OIO71_RS18075	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO71_RS18115	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO71_RS18125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO71_RS18195	COG0758	DNA mediated transformation
OIO71_RS18205	COG0697	spore germination
OIO71_RS18210	COG1309	transcriptional regulator
OIO71_RS18225	COG0386	Belongs to the glutathione peroxidase family
OIO71_RS18290	COG1121	(ABC) transporter
OIO71_RS18295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO71_RS18300	COG1280	lysine exporter protein (LysE YggA)
OIO71_RS18305	COG2837	iron assimilation
OIO71_RS18315	COG0281	malic enzyme
OIO71_RS18360	COG0519	Catalyzes the synthesis of GMP from XMP
OIO71_RS18360	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO71_RS18365	COG4399	Belongs to the UPF0754 family
OIO71_RS18370	COG2259	Doxx family
OIO71_RS18375	COG0586	Pfam SNARE associated Golgi protein
OIO71_RS18390	COG1192	Involved in chromosome partitioning
OIO71_RS18400	COG0271	Belongs to the BolA IbaG family
OIO71_RS18420	COG2267	carboxylic ester hydrolase activity
OIO71_RS18440	COG3321	synthase
OIO71_RS18440	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO71_RS18440	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO71_RS18440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO71_RS18445	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS18455	COG2197	response regulator
OIO71_RS18465	COG3916	Acyl-homoserine-lactone synthase
OIO71_RS18470	COG0477	Major facilitator Superfamily
OIO71_RS18475	COG1024	Enoyl-CoA hydratase
OIO71_RS18480	COG1024	Enoyl-CoA hydratase
OIO71_RS18485	COG1960	acyl-CoA dehydrogenase activity
OIO71_RS18490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO71_RS18510	COG1113	amino acid transport
OIO71_RS18515	COG1113	amino acid transport
OIO71_RS18520	COG0251	oxidation-reduction process
OIO71_RS18560	COG0564	pseudouridine synthase activity
OIO71_RS18590	COG1051	belongs to the nudix hydrolase family
OIO71_RS18615	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO71_RS18630	COG1802	Transcriptional regulator
OIO71_RS18640	COG1448	Aminotransferase
OIO71_RS18645	COG0277	FAD linked oxidase domain protein
OIO71_RS18655	COG2186	Transcriptional regulator
OIO71_RS18665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO71_RS18670	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO71_RS18685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO71_RS18695	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OIO71_RS18705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO71_RS18710	COG0438	transferase activity, transferring glycosyl groups
OIO71_RS18720	COG0438	transferase activity, transferring glycosyl groups
OIO71_RS18740	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO71_RS18770	COG0728	peptidoglycan biosynthetic process
OIO71_RS18775	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO71_RS18810	COG1017	nitric oxide dioxygenase activity
OIO71_RS18810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO71_RS18835	COG0546	phosphoglycolate phosphatase activity
OIO71_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
OIO71_RS18860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO71_RS18865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO71_RS18870	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO71_RS18875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO71_RS18880	COG1116	anion transmembrane transporter activity
OIO71_RS18885	COG1309	transcriptional regulator
OIO71_RS18890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO71_RS18900	COG0196	riboflavin kinase activity
OIO71_RS18905	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO71_RS18915	COG1047	Peptidyl-prolyl cis-trans
OIO71_RS18955	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO71_RS18960	COG0657	acetylesterase activity
OIO71_RS18980	COG0583	DNA-binding transcription factor activity
OIO71_RS19010	COG2951	lytic endotransglycosylase activity
OIO71_RS19015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO71_RS19030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO71_RS19040	COG0671	phosphoesterase, PA-phosphatase related
OIO71_RS19045	COG0861	Integral membrane protein TerC family
OIO71_RS19055	COG0754	glutathionylspermidine amidase activity
OIO71_RS19065	COG0402	S-adenosylhomocysteine deaminase activity
OIO71_RS19080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO71_RS19085	COG1230	cation diffusion facilitator family transporter
OIO71_RS19100	COG0706	membrane insertase activity
OIO71_RS19200	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO71_RS19235	COG4683	PFAM Phage derived protein Gp49-like (DUF891)