locus-tag	class	description
OIO62_RS00010	COG0592	DNA-directed DNA polymerase activity
OIO62_RS00020	COG0187	DNA topoisomerase II activity
OIO62_RS00030	COG0586	Pfam SNARE associated Golgi protein
OIO62_RS00035	COG0488	(ABC) transporter
OIO62_RS00060	COG0596	Alpha beta hydrolase
OIO62_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OIO62_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OIO62_RS00115	COG0733	neurotransmitter:sodium symporter activity
OIO62_RS00150	COG0583	DNA-binding transcription factor activity
OIO62_RS00155	COG2233	PERMEase
OIO62_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS00205	COG2814	Major facilitator Superfamily
OIO62_RS00210	COG0656	L-ascorbic acid biosynthetic process
OIO62_RS00215	COG0583	DNA-binding transcription factor activity
OIO62_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO62_RS00235	COG1064	alcohol dehydrogenase
OIO62_RS00240	COG2818	Glycosylase
OIO62_RS00255	COG1194	a g-specific adenine glycosylase
OIO62_RS00275	COG2983	Belongs to the UPF0260 family
OIO62_RS00280	COG2133	pyrroloquinoline quinone binding
OIO62_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OIO62_RS00290	COG2116	formate transmembrane transporter activity
OIO62_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO62_RS00315	COG1335	isochorismatase
OIO62_RS00320	COG0385	Bile acid
OIO62_RS00325	COG0534	Mate efflux family protein
OIO62_RS00330	COG1683	Conserved Protein
OIO62_RS00350	COG0625	glutathione transferase activity
OIO62_RS00360	COG1113	amino acid transport
OIO62_RS00370	COG0523	cobalamin synthesis protein
OIO62_RS00380	COG2188	Transcriptional regulator
OIO62_RS00410	COG0010	Belongs to the arginase family
OIO62_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO62_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OIO62_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OIO62_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OIO62_RS00530	COG0534	Mate efflux family protein
OIO62_RS00535	COG0436	Aminotransferase
OIO62_RS00540	COG2733	membrane
OIO62_RS00555	COG2918	glutathione biosynthetic process
OIO62_RS00570	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS00580	COG3951	Flagellar rod assembly protein muramidase FlgJ
OIO62_RS00580	COG1705	Flagellar rod assembly protein muramidase FlgJ
OIO62_RS00620	COG3150	esterase
OIO62_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
OIO62_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO62_RS00650	COG2233	PERMEase
OIO62_RS00655	COG2351	hydroxyisourate hydrolase activity
OIO62_RS00690	COG3706	GGDEF domain
OIO62_RS00705	COG1393	Belongs to the ArsC family
OIO62_RS00710	COG0708	Exodeoxyribonuclease III
OIO62_RS00740	COG0189	ligase activity
OIO62_RS00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OIO62_RS00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OIO62_RS00785	COG4942	peptidase
OIO62_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO62_RS00805	COG2119	membrane
OIO62_RS00810	COG4774	siderophore transport
OIO62_RS00815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO62_RS00815	COG0426	domain, Protein
OIO62_RS00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OIO62_RS00860	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS00865	COG1519	Transferase
OIO62_RS00870	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO62_RS00875	COG0668	transmembrane transport
OIO62_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO62_RS00890	COG1335	isochorismatase
OIO62_RS00895	COG1522	sequence-specific DNA binding
OIO62_RS00920	COG2205	protein histidine kinase activity
OIO62_RS00920	COG2198	Histidine kinase
OIO62_RS00920	COG0784	Response regulator, receiver
OIO62_RS00925	COG3162	membrane
OIO62_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO62_RS00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OIO62_RS00965	COG1309	transcriptional regulator
OIO62_RS00985	COG0351	phosphomethylpyrimidine kinase
OIO62_RS00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO62_RS00985	COG0352	thiamine-phosphate diphosphorylase activity
OIO62_RS00995	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS01005	COG2015	COG2015, Alkyl sulfatase and related hydrolases
OIO62_RS01015	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS01025	COG2814	Major facilitator Superfamily
OIO62_RS01040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO62_RS01050	COG1113	amino acid transport
OIO62_RS01060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO62_RS01065	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS01075	COG1335	isochorismatase
OIO62_RS01105	COG2814	Major facilitator Superfamily
OIO62_RS01110	COG0583	DNA-binding transcription factor activity
OIO62_RS01130	COG0667	Aldo Keto reductase
OIO62_RS01165	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS01185	COG1733	regulation of RNA biosynthetic process
OIO62_RS01190	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO62_RS01255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OIO62_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OIO62_RS01325	COG0427	acetyl-CoA hydrolase
OIO62_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
OIO62_RS01355	COG4221	oxidoreductase activity
OIO62_RS01360	COG2873	o-acetylhomoserine
OIO62_RS01365	COG0488	(ABC) transporter
OIO62_RS01460	COG0833	amino acid
OIO62_RS01505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OIO62_RS01510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OIO62_RS01525	COG2226	methyltransferase
OIO62_RS01575	COG0070	glutamate synthase
OIO62_RS01575	COG0067	glutamate synthase
OIO62_RS01575	COG0069	glutamate synthase activity
OIO62_RS01580	COG0493	'glutamate synthase
OIO62_RS01590	COG1704	LemA family
OIO62_RS01595	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OIO62_RS01605	COG4969	Belongs to the N-Me-Phe pilin family
OIO62_RS01630	COG1061	Type III restriction enzyme res subunit
OIO62_RS01635	COG1002	Type II restriction enzyme, methylase subunits
OIO62_RS01660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO62_RS01675	COG0194	GDP metabolic process
OIO62_RS01725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OIO62_RS01745	COG5380	lipid catabolic process
OIO62_RS01750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OIO62_RS01775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OIO62_RS01780	COG0277	FAD linked oxidase domain protein
OIO62_RS01790	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OIO62_RS01795	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO62_RS01810	COG1289	transmembrane transporter activity
OIO62_RS01820	COG0628	permease
OIO62_RS01825	COG1192	Involved in chromosome partitioning
OIO62_RS01855	COG0833	amino acid
OIO62_RS01860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO62_RS01865	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO62_RS01875	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS01915	COG0583	DNA-binding transcription factor activity
OIO62_RS01935	COG0752	glycyl-tRNA synthetase alpha subunit
OIO62_RS01960	COG0517	IMP dehydrogenase activity
OIO62_RS01965	COG1983	PspC domain protein
OIO62_RS01975	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS01990	COG0408	coproporphyrinogen oxidase activity
OIO62_RS02010	COG0513	Belongs to the DEAD box helicase family
OIO62_RS02020	COG1127	ABC transporter
OIO62_RS02025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OIO62_RS02035	COG2854	intermembrane phospholipid transfer
OIO62_RS02045	COG0598	Magnesium transport protein CorA
OIO62_RS02055	COG0494	nUDIX hydrolase
OIO62_RS02060	COG1040	competence protein
OIO62_RS02065	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OIO62_RS02085	COG1946	Acyl-CoA thioesterase
OIO62_RS02090	COG1301	dicarboxylic acid transport
OIO62_RS02105	COG1959	2 iron, 2 sulfur cluster binding
OIO62_RS02110	COG1017	nitric oxide dioxygenase activity
OIO62_RS02110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO62_RS02120	COG0433	COG0433 Predicted ATPase
OIO62_RS02125	COG0626	cystathionine gamma-synthase activity
OIO62_RS02280	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS02285	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OIO62_RS02315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OIO62_RS02320	COG0339	signal peptide processing
OIO62_RS02325	COG0557	exoribonuclease II activity
OIO62_RS02370	COG0179	Fumarylacetoacetate (FAA) hydrolase
OIO62_RS02375	COG2169	Transcriptional regulator
OIO62_RS02380	COG0697	spore germination
OIO62_RS02385	COG1295	ribonuclease BN
OIO62_RS02420	COG1702	phosphate starvation-inducible protein PhoH
OIO62_RS02430	COG0739	heme binding
OIO62_RS02430	COG0741	lytic transglycosylase activity
OIO62_RS02430	COG1196	nuclear chromosome segregation
OIO62_RS02460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OIO62_RS02465	COG1183	phosphatidylcholine synthase activity
OIO62_RS02510	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS02515	COG1309	transcriptional regulator
OIO62_RS02530	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO62_RS02535	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS02555	COG2969	positive regulation of protein catabolic process
OIO62_RS02565	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OIO62_RS02575	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OIO62_RS02580	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OIO62_RS02585	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OIO62_RS02605	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OIO62_RS02615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO62_RS02620	COG1408	metallophosphoesterase
OIO62_RS02630	COG2199	diguanylate cyclase activity
OIO62_RS02690	COG1607	acyl-coa hydrolase
OIO62_RS02725	COG3013	Belongs to the UPF0304 family
OIO62_RS02805	COG2205	protein histidine kinase activity
OIO62_RS02820	COG2132	Multicopper oxidase
OIO62_RS02845	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO62_RS02895	COG0582	viral genome integration into host DNA
OIO62_RS02920	COG2350	Protein conserved in bacteria
OIO62_RS02930	COG0613	PHP domain protein
OIO62_RS02935	COG3781	membrane
OIO62_RS02945	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OIO62_RS02950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OIO62_RS02960	COG1862	Preprotein translocase
OIO62_RS03000	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OIO62_RS03015	COG0726	polysaccharide deacetylase
OIO62_RS03020	COG0438	transferase activity, transferring glycosyl groups
OIO62_RS03040	COG0438	transferase activity, transferring glycosyl groups
OIO62_RS03045	COG1216	Glycosyl transferase, family 2
OIO62_RS03050	COG0438	transferase activity, transferring glycosyl groups
OIO62_RS03095	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS03100	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS03110	COG2205	protein histidine kinase activity
OIO62_RS03115	COG0745	RESPONSE REGULATOR receiver
OIO62_RS03120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OIO62_RS03140	COG2096	Adenosyltransferase
OIO62_RS03190	COG0285	dihydrofolate synthase activity
OIO62_RS03210	COG0450	alkyl hydroperoxide reductase
OIO62_RS03225	COG0477	Major facilitator Superfamily
OIO62_RS03230	COG1272	protein, Hemolysin III
OIO62_RS03270	COG0183	Belongs to the thiolase family
OIO62_RS03275	COG2207	Transcriptional regulator
OIO62_RS03295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO62_RS03315	COG0183	Belongs to the thiolase family
OIO62_RS03325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OIO62_RS03325	COG2885	chlorophyll binding
OIO62_RS03335	COG1690	Belongs to the RtcB family
OIO62_RS03340	COG0833	amino acid
OIO62_RS03350	COG2233	PERMEase
OIO62_RS03355	COG1217	gtp-binding protein TYPA
OIO62_RS03380	COG2094	Belongs to the DNA glycosylase MPG family
OIO62_RS03390	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS03405	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO62_RS03410	COG0354	folic acid binding
OIO62_RS03420	COG3189	MarR family transcriptional regulator
OIO62_RS03425	COG2824	Alkylphosphonate utilization operon protein PhnA
OIO62_RS03430	COG3422	double-strand break repair
OIO62_RS03470	COG0840	transmembrane signaling receptor activity
OIO62_RS03490	COG5510	response to toxic substance
OIO62_RS03500	COG2832	Protein of unknown function (DUF454)
OIO62_RS03505	COG1376	ErfK ybiS ycfS ynhG family protein
OIO62_RS03545	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OIO62_RS03555	COG1289	transmembrane transporter activity
OIO62_RS03560	COG2814	Major facilitator Superfamily
OIO62_RS03580	COG1115	amino acid carrier protein
OIO62_RS03585	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO62_RS03590	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO62_RS03595	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
OIO62_RS03625	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO62_RS03635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OIO62_RS03640	COG1077	Cell shape determining protein MreB Mrl
OIO62_RS03645	COG1792	Involved in formation and maintenance of cell shape
OIO62_RS03650	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OIO62_RS03655	COG0424	maF-like protein
OIO62_RS03660	COG1530	ribonuclease E activity
OIO62_RS03670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO62_RS03680	COG0560	Phosphoserine phosphatase
OIO62_RS03690	COG2249	NAD(P)H dehydrogenase (quinone) activity
OIO62_RS03715	COG2207	Transcriptional regulator
OIO62_RS03735	COG1113	amino acid transport
OIO62_RS03740	COG2828	Protein conserved in bacteria
OIO62_RS03745	COG0142	geranyltranstransferase activity
OIO62_RS03750	COG2315	Protein conserved in bacteria
OIO62_RS03765	COG1752	Esterase of the alpha-beta hydrolase superfamily
OIO62_RS03780	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS03790	COG2194	sulfuric ester hydrolase activity
OIO62_RS03795	COG0745	RESPONSE REGULATOR receiver
OIO62_RS03800	COG0642	Histidine kinase
OIO62_RS03810	COG0004	ammonium transporteR
OIO62_RS03815	COG0583	DNA-binding transcription factor activity
OIO62_RS03835	COG0525	valine-tRNA ligase activity
OIO62_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS03855	COG0393	Putative heavy-metal-binding
OIO62_RS03860	COG0393	Putative heavy-metal-binding
OIO62_RS03865	COG1538	Outer membrane efflux protein
OIO62_RS03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS03880	COG0671	phosphoesterase, PA-phosphatase related
OIO62_RS03910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OIO62_RS03925	COG1648	precorrin-2 dehydrogenase activity
OIO62_RS03925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OIO62_RS03930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OIO62_RS03935	COG1733	regulation of RNA biosynthetic process
OIO62_RS03945	COG0531	amino acid
OIO62_RS03960	COG0321	lipoyl(octanoyl) transferase activity
OIO62_RS03965	COG2921	Belongs to the UPF0250 family
OIO62_RS04000	COG2009	succinate dehydrogenase
OIO62_RS04005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OIO62_RS04010	COG1053	succinate dehydrogenase
OIO62_RS04015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OIO62_RS04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO62_RS04060	COG2354	Protein conserved in bacteria
OIO62_RS04065	COG2321	neutral zinc metallopeptidase
OIO62_RS04085	COG2843	Capsule synthesis protein
OIO62_RS04100	COG0589	response to stress
OIO62_RS04120	COG0505	Belongs to the CarA family
OIO62_RS04145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO62_RS04150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OIO62_RS04200	COG0477	Major facilitator Superfamily
OIO62_RS04205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OIO62_RS04220	COG1597	lipid kinase activity
OIO62_RS04225	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO62_RS04300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO62_RS04305	COG0584	glycerophosphoryl diester phosphodiesterase
OIO62_RS04325	COG0741	lytic transglycosylase activity
OIO62_RS04345	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OIO62_RS04360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO62_RS04370	COG3811	Belongs to the UPF0386 family
OIO62_RS04390	COG2801	Transposase and inactivated derivatives
OIO62_RS04415	COG0778	Nitroreductase
OIO62_RS04430	COG1929	Belongs to the glycerate kinase type-1 family
OIO62_RS04435	COG0243	molybdopterin cofactor binding
OIO62_RS04440	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OIO62_RS04445	COG3339	Conserved Protein
OIO62_RS04455	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OIO62_RS04470	COG1113	amino acid transport
OIO62_RS04480	COG0019	diaminopimelate decarboxylase activity
OIO62_RS04490	COG1280	lysine exporter protein (LysE YggA)
OIO62_RS04495	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO62_RS04525	COG0463	Glycosyl transferase, family 2
OIO62_RS04545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS04580	COG4591	ABC-type transport system involved in lipoprotein release permease component
OIO62_RS04585	COG1136	(ABC) transporter
OIO62_RS04590	COG2333	competence protein COMEC
OIO62_RS04590	COG0658	competence protein
OIO62_RS04600	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OIO62_RS04600	COG0616	signal peptide processing
OIO62_RS04605	COG0596	Alpha beta hydrolase
OIO62_RS04610	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OIO62_RS04620	COG0628	permease
OIO62_RS04640	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS04665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO62_RS04685	COG0823	Involved in the tonB-independent uptake of proteins
OIO62_RS04705	COG0824	Thioesterase
OIO62_RS04710	COG1473	amidohydrolase
OIO62_RS04730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OIO62_RS04730	COG0047	phosphoribosylformylglycinamidine synthase activity
OIO62_RS04735	COG2814	Major facilitator Superfamily
OIO62_RS04750	COG1024	Enoyl-CoA hydratase
OIO62_RS04755	COG1051	belongs to the nudix hydrolase family
OIO62_RS04755	COG1056	cytidyltransferase-related domain
OIO62_RS04765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OIO62_RS04780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OIO62_RS04795	COG4625	pathogenesis
OIO62_RS04800	COG0583	DNA-binding transcription factor activity
OIO62_RS04805	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OIO62_RS04810	COG4208	sulfate ABC transporter
OIO62_RS04815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OIO62_RS04825	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OIO62_RS04830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OIO62_RS04835	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OIO62_RS04855	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO62_RS04865	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OIO62_RS04875	COG0681	Belongs to the peptidase S26 family
OIO62_RS04890	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OIO62_RS04900	COG1381	Involved in DNA repair and RecF pathway recombination
OIO62_RS04905	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OIO62_RS04915	COG4221	oxidoreductase activity
OIO62_RS04945	COG0436	Aminotransferase
OIO62_RS04965	COG0556	nucleotide-excision repair
OIO62_RS05020	COG2070	2-Nitropropane dioxygenase
OIO62_RS05050	COG1215	transferase activity, transferring glycosyl groups
OIO62_RS05065	COG0415	Belongs to the DNA photolyase family
OIO62_RS05075	COG1252	NADH dehydrogenase
OIO62_RS05080	COG1686	Belongs to the peptidase S11 family
OIO62_RS05095	COG1187	pseudouridine synthase activity
OIO62_RS05120	COG0477	Major facilitator Superfamily
OIO62_RS05125	COG0583	DNA-binding transcription factor activity
OIO62_RS05130	COG1823	symporter activity
OIO62_RS05140	COG0612	Peptidase, M16
OIO62_RS05165	COG0352	thiamine-phosphate diphosphorylase activity
OIO62_RS05200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO62_RS05225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OIO62_RS05230	COG0076	glutamate decarboxylase activity
OIO62_RS05240	COG1522	sequence-specific DNA binding
OIO62_RS05245	COG3961	Belongs to the TPP enzyme family
OIO62_RS05250	COG1113	amino acid transport
OIO62_RS05255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OIO62_RS05260	COG0573	inorganic phosphate transmembrane transporter activity
OIO62_RS05270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OIO62_RS05275	COG0616	signal peptide processing
OIO62_RS05310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OIO62_RS05315	COG1686	Belongs to the peptidase S11 family
OIO62_RS05340	COG0583	DNA-binding transcription factor activity
OIO62_RS05345	COG1067	ATP-dependent peptidase activity
OIO62_RS05370	COG4943	cyclic-guanylate-specific phosphodiesterase activity
OIO62_RS05390	COG1966	Carbon starvation protein
OIO62_RS05395	COG2879	small protein
OIO62_RS05415	COG2801	Transposase and inactivated derivatives
OIO62_RS05435	COG1741	Belongs to the pirin family
OIO62_RS05445	COG2964	Protein conserved in bacteria
OIO62_RS05460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO62_RS05465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO62_RS05470	COG4605	iron ion homeostasis
OIO62_RS05475	COG4604	ABC transporter, ATP-binding protein
OIO62_RS05480	COG4607	ABC-type enterochelin transport system periplasmic component
OIO62_RS05485	COG4774	siderophore transport
OIO62_RS05495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OIO62_RS05500	COG1021	2,3-dihydroxybenzoate-AMP ligase
OIO62_RS05505	COG1535	isochorismatase
OIO62_RS05505	COG3433	isochorismatase activity
OIO62_RS05515	COG1132	(ABC) transporter
OIO62_RS05520	COG1132	(ABC) transporter
OIO62_RS05525	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
OIO62_RS05530	COG2977	Belongs to the P-Pant transferase superfamily
OIO62_RS05535	COG1169	isochorismate synthase
OIO62_RS05550	COG3739	integral membrane protein
OIO62_RS05570	COG0302	gtp cyclohydrolase
OIO62_RS05580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
OIO62_RS05610	COG0308	aminopeptidase N
OIO62_RS05615	COG0512	Glutamine amidotransferase of anthranilate synthase
OIO62_RS05630	COG0174	glutamine synthetase
OIO62_RS05640	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OIO62_RS05675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OIO62_RS05680	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OIO62_RS05685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OIO62_RS05705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OIO62_RS05710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
OIO62_RS05715	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OIO62_RS05730	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS05735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO62_RS05740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO62_RS05750	COG2223	nitrite transmembrane transporter activity
OIO62_RS05760	COG0024	Methionine aminopeptidase
OIO62_RS05765	COG0052	Belongs to the universal ribosomal protein uS2 family
OIO62_RS05780	COG2207	Transcriptional regulator
OIO62_RS05805	COG2951	lytic endotransglycosylase activity
OIO62_RS05810	COG0772	Belongs to the SEDS family
OIO62_RS05825	COG0842	Transport permease protein
OIO62_RS05830	COG1131	(ABC) transporter
OIO62_RS05875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS05890	COG4215	(ABC) transporter
OIO62_RS05895	COG4160	amino acid transport
OIO62_RS05900	COG4598	ABC transporter
OIO62_RS05910	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO62_RS05915	COG0826	peptidase U32
OIO62_RS05920	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO62_RS05935	COG1720	tRNA m6t6A37 methyltransferase activity
OIO62_RS05945	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OIO62_RS05960	COG0642	Histidine kinase
OIO62_RS05970	COG0494	nUDIX hydrolase
OIO62_RS05980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OIO62_RS05985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OIO62_RS05990	COG3139	Protein of unknown function (DUF1315)
OIO62_RS06000	COG1301	dicarboxylic acid transport
OIO62_RS06005	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS06010	COG2819	hydrolase of the alpha beta superfamily
OIO62_RS06020	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OIO62_RS06030	COG2195	Cleaves the N-terminal amino acid of tripeptides
OIO62_RS06035	COG1234	tRNA 3'-trailer cleavage
OIO62_RS06065	COG2363	Small membrane protein
OIO62_RS06090	COG0513	Belongs to the DEAD box helicase family
OIO62_RS06100	COG0778	Nitroreductase
OIO62_RS06130	COG1286	toxin biosynthetic process
OIO62_RS06155	COG4783	chaperone-mediated protein folding
OIO62_RS06160	COG1610	YqeY-like protein
OIO62_RS06215	COG2831	hemolysin activation secretion protein
OIO62_RS06220	COG3210	domain, Protein
OIO62_RS06220	COG3210	domain, Protein
OIO62_RS06220	COG3210	domain, Protein
OIO62_RS06285	COG3111	PFAM Bacterial OB fold (BOF) protein
OIO62_RS06310	COG3243	poly(R)-hydroxyalkanoic acid synthase
OIO62_RS06315	COG0786	glutamate:sodium symporter activity
OIO62_RS06325	COG2186	Transcriptional regulator
OIO62_RS06375	COG0477	Major facilitator Superfamily
OIO62_RS06405	COG2995	paraquat-inducible protein a
OIO62_RS06410	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OIO62_RS06410	COG3008	intermembrane lipid transfer
OIO62_RS06420	COG2351	hydroxyisourate hydrolase activity
OIO62_RS06460	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OIO62_RS06470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OIO62_RS06475	COG0642	Histidine kinase
OIO62_RS06480	COG0745	RESPONSE REGULATOR receiver
OIO62_RS06500	COG1794	racemase activity, acting on amino acids and derivatives
OIO62_RS06530	COG1301	dicarboxylic acid transport
OIO62_RS06540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO62_RS06545	COG2011	ABC-type metal ion transport system permease component
OIO62_RS06550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO62_RS06555	COG1464	Belongs to the NlpA lipoprotein family
OIO62_RS06560	COG0151	Belongs to the GarS family
OIO62_RS06565	COG0138	bifunctional purine biosynthesis protein purh
OIO62_RS06570	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OIO62_RS06600	COG2308	Evidence 4 Homologs of previously reported genes of
OIO62_RS06610	COG1305	Transglutaminase-like
OIO62_RS06620	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OIO62_RS06625	COG0305	Participates in initiation and elongation during chromosome replication
OIO62_RS06650	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OIO62_RS06660	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OIO62_RS06665	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OIO62_RS06690	COG1649	PFAM Uncharacterised BCR, COG1649
OIO62_RS06690	COG0726	polysaccharide deacetylase
OIO62_RS06695	COG1215	transferase activity, transferring glycosyl groups
OIO62_RS06700	COG3658	cytochrome
OIO62_RS06710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO62_RS06725	COG0583	DNA-binding transcription factor activity
OIO62_RS06745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO62_RS06750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO62_RS06765	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS06770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO62_RS06775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO62_RS06800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OIO62_RS06805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OIO62_RS06815	COG2205	protein histidine kinase activity
OIO62_RS06820	COG0745	RESPONSE REGULATOR receiver
OIO62_RS06825	COG0174	glutamine synthetase
OIO62_RS06845	COG0729	surface antigen
OIO62_RS06870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO62_RS06875	COG2814	Major facilitator Superfamily
OIO62_RS06890	COG0583	DNA-binding transcription factor activity
OIO62_RS06905	COG1187	pseudouridine synthase activity
OIO62_RS06925	COG0802	atpase or kinase
OIO62_RS06930	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OIO62_RS06940	COG1923	regulation of RNA biosynthetic process
OIO62_RS06945	COG0697	spore germination
OIO62_RS06960	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO62_RS06970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO62_RS06975	COG0519	Catalyzes the synthesis of GMP from XMP
OIO62_RS06975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO62_RS06980	COG4302	ethanolamine ammonia-lyase activity
OIO62_RS06985	COG4303	Ethanolamine ammonia lyase large subunit
OIO62_RS06990	COG0531	amino acid
OIO62_RS07010	COG1454	alcohol dehydrogenase
OIO62_RS07015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO62_RS07025	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OIO62_RS07045	COG0308	aminopeptidase N
OIO62_RS07085	COG1605	Chorismate mutase
OIO62_RS07100	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OIO62_RS07115	COG2801	Transposase and inactivated derivatives
OIO62_RS07125	COG1309	transcriptional regulator
OIO62_RS07135	COG0668	transmembrane transport
OIO62_RS07165	COG4773	Receptor
OIO62_RS07185	COG0488	(ABC) transporter
OIO62_RS07190	COG0589	response to stress
OIO62_RS07215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OIO62_RS07225	COG3135	benzoate transporter
OIO62_RS07230	COG1522	sequence-specific DNA binding
OIO62_RS07240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OIO62_RS07245	COG0583	DNA-binding transcription factor activity
OIO62_RS07255	COG0183	Belongs to the thiolase family
OIO62_RS07265	COG2030	dehydratase
OIO62_RS07295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OIO62_RS07310	COG0824	Thioesterase
OIO62_RS07315	COG1454	alcohol dehydrogenase
OIO62_RS07325	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OIO62_RS07345	COG0069	glutamate synthase activity
OIO62_RS07475	COG1484	DNA-dependent DNA replication
OIO62_RS07665	COG2026	Addiction module toxin, RelE StbE family
OIO62_RS07705	COG0592	DNA-directed DNA polymerase activity
OIO62_RS07775	COG2814	Major facilitator Superfamily
OIO62_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
OIO62_RS07810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO62_RS07810	COG1116	anion transmembrane transporter activity
OIO62_RS07815	COG0745	RESPONSE REGULATOR receiver
OIO62_RS07825	COG2146	nitrite reductase [NAD(P)H] activity
OIO62_RS07825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO62_RS07830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO62_RS07835	COG0243	molybdopterin cofactor binding
OIO62_RS07845	COG0243	molybdopterin cofactor binding
OIO62_RS07850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OIO62_RS07865	COG0315	cyclic pyranopterin monophosphate synthase activity
OIO62_RS07865	COG0521	Mo-molybdopterin cofactor biosynthetic process
OIO62_RS07870	COG0303	'Molybdopterin
OIO62_RS07880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO62_RS07885	COG0697	spore germination
OIO62_RS07905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OIO62_RS07910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO62_RS07965	COG2204	response regulator
OIO62_RS07970	COG3852	Histidine kinase
OIO62_RS07995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OIO62_RS08000	COG0575	Belongs to the CDS family
OIO62_RS08015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO62_RS08035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO62_RS08050	COG2137	regulation of response to DNA damage stimulus
OIO62_RS08060	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OIO62_RS08065	COG1011	Hydrolase
OIO62_RS08080	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS08095	COG1522	sequence-specific DNA binding
OIO62_RS08105	COG1113	amino acid transport
OIO62_RS08125	COG0659	secondary active sulfate transmembrane transporter activity
OIO62_RS08130	COG2135	peptidase activity
OIO62_RS08145	COG3300	MHYT domain
OIO62_RS08145	COG5001	Diguanylate cyclase
OIO62_RS08160	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO62_RS08160	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OIO62_RS08160	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OIO62_RS08165	COG1105	Belongs to the carbohydrate kinase PfkB family
OIO62_RS08170	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OIO62_RS08170	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO62_RS08200	COG0024	Methionine aminopeptidase
OIO62_RS08205	COG0583	DNA-binding transcription factor activity
OIO62_RS08215	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OIO62_RS08220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OIO62_RS08225	COG0517	IMP dehydrogenase activity
OIO62_RS08225	COG0516	GMP reductase activity
OIO62_RS08250	COG0552	protein localization to endoplasmic reticulum
OIO62_RS08260	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OIO62_RS08275	COG4890	Cyd operon protein YbgT
OIO62_RS08280	COG1294	oxidase, subunit
OIO62_RS08295	COG1585	Membrane protein implicated in regulation of membrane protease activity
OIO62_RS08305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OIO62_RS08310	COG4774	siderophore transport
OIO62_RS08325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OIO62_RS08330	COG0569	domain protein
OIO62_RS08335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OIO62_RS08365	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OIO62_RS08370	COG0542	response to heat
OIO62_RS08380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO62_RS08395	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS08395	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO62_RS08440	COG2323	membrane
OIO62_RS08445	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OIO62_RS08455	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO62_RS08460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO62_RS08465	COG0183	Belongs to the thiolase family
OIO62_RS08470	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OIO62_RS08475	COG0596	Alpha beta hydrolase
OIO62_RS08480	COG2271	Major facilitator Superfamily
OIO62_RS08485	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OIO62_RS08490	COG3485	protocatechuate 3,4-dioxygenase
OIO62_RS08495	COG3485	protocatechuate 3,4-dioxygenase
OIO62_RS08500	COG0710	3-dehydroquinate dehydratase activity
OIO62_RS08505	COG3420	alginic acid biosynthetic process
OIO62_RS08510	COG3659	wide pore channel activity
OIO62_RS08515	COG4993	Dehydrogenase
OIO62_RS08525	COG2391	methyltransferase activity
OIO62_RS08540	COG1414	Transcriptional regulator
OIO62_RS08545	COG0583	DNA-binding transcription factor activity
OIO62_RS08550	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS08575	COG2814	Major facilitator Superfamily
OIO62_RS08585	COG0154	amidase activity
OIO62_RS08605	COG4638	Rieske (2fe-2S)
OIO62_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS08625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO62_RS08635	COG3733	amine oxidase
OIO62_RS08645	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS08655	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO62_RS08660	COG0183	Belongs to the thiolase family
OIO62_RS08665	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO62_RS08670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO62_RS08680	COG4829	muconolactone delta-isomerase
OIO62_RS08685	COG4948	Mandelate Racemase Muconate Lactonizing
OIO62_RS08690	COG0583	DNA-binding transcription factor activity
OIO62_RS08700	COG2186	Transcriptional regulator
OIO62_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS08735	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO62_RS08735	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS08775	COG1309	transcriptional regulator
OIO62_RS08785	COG1335	isochorismatase
OIO62_RS08790	COG0583	DNA-binding transcription factor activity
OIO62_RS08800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO62_RS08800	COG0475	glutathione-regulated potassium exporter activity
OIO62_RS08810	COG1473	amidohydrolase
OIO62_RS08825	COG4191	Histidine kinase
OIO62_RS08860	COG2188	Transcriptional regulator
OIO62_RS08875	COG0583	DNA-binding transcription factor activity
OIO62_RS08890	COG1566	PFAM secretion protein HlyD family protein
OIO62_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS08910	COG0129	dihydroxy-acid dehydratase activity
OIO62_RS08920	COG0583	DNA-binding transcription factor activity
OIO62_RS08925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OIO62_RS08935	COG2084	Dehydrogenase
OIO62_RS08940	COG2207	Transcriptional regulator
OIO62_RS08955	COG1064	alcohol dehydrogenase
OIO62_RS08965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OIO62_RS08970	COG1120	ATPase activity
OIO62_RS08990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO62_RS09040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OIO62_RS09080	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS09125	COG2207	Transcriptional regulator
OIO62_RS09135	COG2205	protein histidine kinase activity
OIO62_RS09155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS09160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO62_RS09175	COG3539	Fimbrial protein
OIO62_RS09200	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO62_RS09210	COG0753	catalase activity
OIO62_RS09230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OIO62_RS09290	COG1535	isochorismatase
OIO62_RS09290	COG3433	isochorismatase activity
OIO62_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS09300	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OIO62_RS09305	COG4149	molybdate abc transporter
OIO62_RS09310	COG0725	ABC transporter, periplasmic molybdate-binding protein
OIO62_RS09320	COG4638	Rieske (2fe-2S)
OIO62_RS09325	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO62_RS09330	COG0543	2 iron, 2 sulfur cluster binding
OIO62_RS09330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO62_RS09345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO62_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS09370	COG2207	Transcriptional regulator
OIO62_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS09380	COG2610	gluconate transmembrane transporter activity
OIO62_RS09390	COG1309	transcriptional regulator
OIO62_RS09410	COG0583	DNA-binding transcription factor activity
OIO62_RS09425	COG2031	fatty acid transporter
OIO62_RS09430	COG0183	Belongs to the thiolase family
OIO62_RS09435	COG0583	DNA-binding transcription factor activity
OIO62_RS09440	COG0583	DNA-binding transcription factor activity
OIO62_RS09455	COG1027	Aspartate ammonia-lyase
OIO62_RS09465	COG0477	Major facilitator Superfamily
OIO62_RS09485	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO62_RS09490	COG4521	taurine ABC transporter
OIO62_RS09505	COG2188	Transcriptional regulator
OIO62_RS09515	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OIO62_RS09520	COG1733	regulation of RNA biosynthetic process
OIO62_RS09525	COG3708	Transcriptional regulator
OIO62_RS09525	COG2207	Transcriptional regulator
OIO62_RS09540	COG0730	response to heat
OIO62_RS09565	COG3781	membrane
OIO62_RS09570	COG1063	alcohol dehydrogenase
OIO62_RS09580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OIO62_RS09585	COG0508	dehydrogenase complex catalyzes the overall conversion of
OIO62_RS09590	COG0022	dehydrogenase e1 component
OIO62_RS09595	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OIO62_RS09600	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OIO62_RS09615	COG3706	GGDEF domain
OIO62_RS09630	COG0133	tryptophan synthase activity
OIO62_RS09640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OIO62_RS09675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OIO62_RS09700	COG2226	methyltransferase
OIO62_RS09755	COG0842	Transport permease protein
OIO62_RS09760	COG0842	Transport permease protein
OIO62_RS09765	COG1131	(ABC) transporter
OIO62_RS09780	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OIO62_RS09785	COG4773	Receptor
OIO62_RS09805	COG0730	response to heat
OIO62_RS09810	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OIO62_RS09825	COG0406	alpha-ribazole phosphatase activity
OIO62_RS09830	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OIO62_RS09845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO62_RS09875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO62_RS09885	COG4264	IucA IucC family
OIO62_RS09890	COG4264	IucA IucC family
OIO62_RS09910	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OIO62_RS09925	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS09930	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS09935	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OIO62_RS09940	COG2207	Transcriptional regulator
OIO62_RS09945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO62_RS09950	COG0776	regulation of translation
OIO62_RS09975	COG0822	iron-sulfur transferase activity
OIO62_RS09980	COG0316	Belongs to the HesB IscA family
OIO62_RS10010	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO62_RS10030	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OIO62_RS10035	COG0702	epimerase
OIO62_RS10070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OIO62_RS10080	COG0339	signal peptide processing
OIO62_RS10140	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OIO62_RS10145	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OIO62_RS10175	COG0776	regulation of translation
OIO62_RS10240	COG0084	hydrolase, TatD family'
OIO62_RS10260	COG1663	tetraacyldisaccharide 4'-kinase activity
OIO62_RS10265	COG1132	(ABC) transporter
OIO62_RS10275	COG0811	peptide transport
OIO62_RS10280	COG1475	DNA binding
OIO62_RS10285	COG1192	Involved in chromosome partitioning
OIO62_RS10295	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OIO62_RS10310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OIO62_RS10315	COG0191	fructose-bisphosphate aldolase activity
OIO62_RS10335	COG0424	maF-like protein
OIO62_RS10340	COG2850	peptidyl-arginine hydroxylation
OIO62_RS10350	COG0640	Transcriptional regulator
OIO62_RS10360	COG3619	membrane
OIO62_RS10365	COG3122	Protein conserved in bacteria
OIO62_RS10370	COG1132	(ABC) transporter
OIO62_RS10390	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
OIO62_RS10395	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OIO62_RS10405	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO62_RS10405	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OIO62_RS10405	COG0506	proline dehydrogenase activity
OIO62_RS10410	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OIO62_RS10425	COG3698	Phosphodiester glycosidase
OIO62_RS10435	COG2353	YceI-like domain
OIO62_RS10445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OIO62_RS10490	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OIO62_RS10490	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OIO62_RS10515	COG3539	Fimbrial protein
OIO62_RS10520	COG3121	Chaperone
OIO62_RS10545	COG0697	spore germination
OIO62_RS10555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
OIO62_RS10565	COG0583	DNA-binding transcription factor activity
OIO62_RS10625	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO62_RS10625	COG0784	Response regulator, receiver
OIO62_RS10630	COG0582	viral genome integration into host DNA
OIO62_RS10640	COG1309	transcriptional regulator
OIO62_RS10655	COG1522	sequence-specific DNA binding
OIO62_RS10665	COG1126	abc transporter atp-binding protein
OIO62_RS10670	COG0765	amino acid transport
OIO62_RS10675	COG0765	amino acid transport
OIO62_RS10705	COG1464	Belongs to the NlpA lipoprotein family
OIO62_RS10715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO62_RS10720	COG2011	ABC-type metal ion transport system permease component
OIO62_RS10725	COG0012	GTP binding
OIO62_RS10750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OIO62_RS10790	COG0386	Belongs to the glutathione peroxidase family
OIO62_RS10800	COG0436	Aminotransferase
OIO62_RS10805	COG1301	dicarboxylic acid transport
OIO62_RS10840	COG3634	alkyl hydroperoxide reductase activity
OIO62_RS10855	COG0583	DNA-binding transcription factor activity
OIO62_RS10860	COG0798	PFAM Bile acid sodium symporter
OIO62_RS10865	COG0640	Transcriptional regulator
OIO62_RS10880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OIO62_RS10890	COG0583	DNA-binding transcription factor activity
OIO62_RS10900	COG1953	Uracil, thiamine, allantoin
OIO62_RS10910	COG2175	clavaminate synthase activity
OIO62_RS10915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO62_RS10920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OIO62_RS10925	COG4521	taurine ABC transporter
OIO62_RS10935	COG0477	Major facilitator Superfamily
OIO62_RS10955	COG1271	oxidase subunit
OIO62_RS10960	COG1294	oxidase, subunit
OIO62_RS10970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OIO62_RS10990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OIO62_RS11010	COG3052	prosthetic group binding
OIO62_RS11015	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OIO62_RS11025	COG0583	DNA-binding transcription factor activity
OIO62_RS11035	COG2814	Major facilitator Superfamily
OIO62_RS11055	COG1346	cytolysis
OIO62_RS11065	COG0583	DNA-binding transcription factor activity
OIO62_RS11070	COG0625	glutathione transferase activity
OIO62_RS11075	COG0625	glutathione transferase activity
OIO62_RS11080	COG0583	DNA-binding transcription factor activity
OIO62_RS11095	COG1045	serine acetyltransferase
OIO62_RS11100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OIO62_RS11105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OIO62_RS11110	COG1280	lysine exporter protein (LysE YggA)
OIO62_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO62_RS11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OIO62_RS11135	COG1126	abc transporter atp-binding protein
OIO62_RS11140	COG0765	amino acid transport
OIO62_RS11145	COG0765	amino acid transport
OIO62_RS11165	COG0784	Response regulator, receiver
OIO62_RS11165	COG2205	protein histidine kinase activity
OIO62_RS11185	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OIO62_RS11205	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS11225	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS11260	COG0583	DNA-binding transcription factor activity
OIO62_RS11280	COG0318	PFAM AMP-dependent synthetase and ligase
OIO62_RS11285	COG1309	transcriptional regulator
OIO62_RS11290	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS11295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OIO62_RS11300	COG1024	Enoyl-CoA hydratase
OIO62_RS11305	COG4770	biotin carboxylase activity
OIO62_RS11315	COG0583	DNA-binding transcription factor activity
OIO62_RS11330	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS11340	COG2814	Major facilitator Superfamily
OIO62_RS11350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
OIO62_RS11355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OIO62_RS11360	COG2814	Major facilitator Superfamily
OIO62_RS11365	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS11370	COG1024	Enoyl-CoA hydratase
OIO62_RS11375	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS11380	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO62_RS11385	COG0183	Belongs to the thiolase family
OIO62_RS11395	COG2814	Major facilitator Superfamily
OIO62_RS11405	COG1024	Enoyl-CoA hydratase
OIO62_RS11420	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS11425	COG2814	Major facilitator Superfamily
OIO62_RS11430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OIO62_RS11435	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
OIO62_RS11450	COG3842	ATPase activity
OIO62_RS11455	COG1840	ABC-type Fe3 transport system, periplasmic component
OIO62_RS11465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO62_RS11470	COG1414	Transcriptional regulator
OIO62_RS11480	COG0583	DNA-binding transcription factor activity
OIO62_RS11485	COG3038	cytochrome b561
OIO62_RS11490	COG0753	catalase activity
OIO62_RS11495	COG2271	Major facilitator Superfamily
OIO62_RS11500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO62_RS11505	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO62_RS11520	COG2207	Transcriptional regulator
OIO62_RS11560	COG2050	protein possibly involved in aromatic compounds catabolism
OIO62_RS11570	COG3327	negative regulation of DNA-templated transcription, initiation
OIO62_RS11575	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
OIO62_RS11580	COG0183	Belongs to the thiolase family
OIO62_RS11585	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO62_RS11590	COG1024	Enoyl-CoA hydratase
OIO62_RS11595	COG1024	Enoyl-CoA hydratase
OIO62_RS11600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO62_RS11605	COG2151	metal-sulfur cluster biosynthetic enzyme
OIO62_RS11610	COG3396	Phenylacetate-CoA oxygenase
OIO62_RS11615	COG3460	Phenylacetate-CoA oxygenase
OIO62_RS11620	COG3396	Phenylacetate-CoA oxygenase
OIO62_RS11625	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS11625	COG2030	dehydratase
OIO62_RS11630	COG1760	l-serine dehydratase
OIO62_RS11635	COG0531	amino acid
OIO62_RS11640	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS11685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO62_RS11715	COG1309	transcriptional regulator
OIO62_RS11740	COG0038	chloride channel
OIO62_RS11745	COG4770	biotin carboxylase activity
OIO62_RS11765	COG1914	H( )-stimulated, divalent metal cation uptake system
OIO62_RS11800	COG1250	3-hydroxyacyl-CoA dehydrogenase
OIO62_RS11835	COG2801	Transposase and inactivated derivatives
OIO62_RS11840	COG1560	Kdo2-lipid A biosynthetic process
OIO62_RS11850	COG5006	permease, DMT superfamily
OIO62_RS11855	COG1522	sequence-specific DNA binding
OIO62_RS11870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OIO62_RS11880	COG4122	O-methyltransferase activity
OIO62_RS11915	COG1137	ATPase activity
OIO62_RS11920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OIO62_RS11930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OIO62_RS11935	COG0517	IMP dehydrogenase activity
OIO62_RS11935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OIO62_RS11970	COG2814	Major facilitator Superfamily
OIO62_RS12005	COG1278	Cold shock
OIO62_RS12010	COG1280	lysine exporter protein (LysE YggA)
OIO62_RS12040	COG1570	exodeoxyribonuclease VII activity
OIO62_RS12090	COG0583	DNA-binding transcription factor activity
OIO62_RS12100	COG4638	Rieske (2fe-2S)
OIO62_RS12105	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
OIO62_RS12110	COG0633	Ferredoxin
OIO62_RS12110	COG0543	2 iron, 2 sulfur cluster binding
OIO62_RS12115	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS12120	COG3135	benzoate transporter
OIO62_RS12125	COG2814	Major facilitator Superfamily
OIO62_RS12140	COG1643	Atp-dependent helicase
OIO62_RS12145	COG0450	alkyl hydroperoxide reductase
OIO62_RS12155	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OIO62_RS12165	COG3634	alkyl hydroperoxide reductase activity
OIO62_RS12185	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OIO62_RS12190	COG0625	glutathione transferase activity
OIO62_RS12200	COG2885	chlorophyll binding
OIO62_RS12235	COG0542	response to heat
OIO62_RS12250	COG1765	OsmC-like protein
OIO62_RS12265	COG0667	Aldo Keto reductase
OIO62_RS12280	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OIO62_RS12290	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OIO62_RS12410	COG1598	PFAM Uncharacterised protein family UPF0150
OIO62_RS12640	COG0527	aspartate kinase activity
OIO62_RS12650	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OIO62_RS12660	COG3038	cytochrome b561
OIO62_RS12665	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OIO62_RS12670	COG2252	PERMEase
OIO62_RS12680	COG2072	flavoprotein involved in K transport
OIO62_RS12695	COG1741	Belongs to the pirin family
OIO62_RS12700	COG1309	transcriptional regulator
OIO62_RS12710	COG0300	oxidoreductase activity
OIO62_RS12715	COG2072	flavoprotein involved in K transport
OIO62_RS12720	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OIO62_RS12765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OIO62_RS12780	COG2814	Major facilitator Superfamily
OIO62_RS12785	COG1024	Enoyl-CoA hydratase
OIO62_RS12790	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS12800	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS12825	COG2186	Transcriptional regulator
OIO62_RS12830	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS12840	COG4948	Mandelate Racemase Muconate Lactonizing
OIO62_RS12845	COG2271	Major facilitator Superfamily
OIO62_RS12850	COG2721	sulfolactate sulfo-lyase activity
OIO62_RS12855	COG0697	spore germination
OIO62_RS12870	COG1113	amino acid transport
OIO62_RS12890	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS12910	COG0531	amino acid
OIO62_RS12920	COG1113	amino acid transport
OIO62_RS12955	COG3209	COG3209 Rhs family protein
OIO62_RS12975	COG2801	Transposase and inactivated derivatives
OIO62_RS13015	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS13015	COG0446	pyridine nucleotide-disulphide oxidoreductase
OIO62_RS13025	COG4251	negative regulation of phosphorylation
OIO62_RS13025	COG3706	GGDEF domain
OIO62_RS13025	COG2203	Gaf domain
OIO62_RS13025	COG5001	Diguanylate cyclase
OIO62_RS13035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO62_RS13055	COG4172	Belongs to the ABC transporter superfamily
OIO62_RS13060	COG4239	(ABC) transporter, permease
OIO62_RS13065	COG4174	ABC transporter (Permease)
OIO62_RS13075	COG1388	LysM domain
OIO62_RS13075	COG0741	lytic transglycosylase activity
OIO62_RS13075	COG1388	LysM domain
OIO62_RS13075	COG0741	lytic transglycosylase activity
OIO62_RS13080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO62_RS13120	COG0583	DNA-binding transcription factor activity
OIO62_RS13125	COG1279	arginine transmembrane transporter activity
OIO62_RS13145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO62_RS13150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO62_RS13155	COG0006	proline dipeptidase activity
OIO62_RS13195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OIO62_RS13230	COG3384	dioxygenase
OIO62_RS13240	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OIO62_RS13245	COG2878	Part of a membrane complex involved in electron transport
OIO62_RS13250	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OIO62_RS13275	COG0768	penicillin binding
OIO62_RS13280	COG0742	ribosomal rna small subunit methyltransferase
OIO62_RS13295	COG0830	nickel cation binding
OIO62_RS13305	COG0804	urea catabolic process
OIO62_RS13345	COG1253	flavin adenine dinucleotide binding
OIO62_RS13350	COG2851	Citrate transporter
OIO62_RS13400	COG1773	rubredoxin
OIO62_RS13405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OIO62_RS13415	COG0583	DNA-binding transcription factor activity
OIO62_RS13445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OIO62_RS13450	COG4181	ATPase activity
OIO62_RS13495	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OIO62_RS13515	COG0306	phosphate transporter
OIO62_RS13525	COG3958	Transketolase
OIO62_RS13530	COG3959	Transketolase, thiamine diphosphate binding domain
OIO62_RS13535	COG2271	Major facilitator Superfamily
OIO62_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS13545	COG0583	DNA-binding transcription factor activity
OIO62_RS13560	COG2223	nitrite transmembrane transporter activity
OIO62_RS13565	COG2207	Transcriptional regulator
OIO62_RS13570	COG2066	Belongs to the glutaminase family
OIO62_RS13575	COG0242	peptide deformylase activity
OIO62_RS13580	COG0477	Major facilitator Superfamily
OIO62_RS13590	COG0028	Belongs to the TPP enzyme family
OIO62_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS13610	COG2267	carboxylic ester hydrolase activity
OIO62_RS13620	COG2271	Major facilitator Superfamily
OIO62_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS13655	COG1414	Transcriptional regulator
OIO62_RS13670	COG1024	Enoyl-CoA hydratase
OIO62_RS13680	COG1215	transferase activity, transferring glycosyl groups
OIO62_RS13685	COG0726	polysaccharide deacetylase
OIO62_RS13685	COG1649	PFAM Uncharacterised BCR, COG1649
OIO62_RS13695	COG4681	YaeQ
OIO62_RS13705	COG0523	cobalamin synthesis protein
OIO62_RS13715	COG1607	acyl-coa hydrolase
OIO62_RS13725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO62_RS13730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OIO62_RS13735	COG1309	transcriptional regulator
OIO62_RS13760	COG2040	homocysteine
OIO62_RS13765	COG0531	amino acid
OIO62_RS13790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO62_RS13795	COG0477	Major facilitator Superfamily
OIO62_RS13840	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS13855	COG0405	Gamma-glutamyltransferase
OIO62_RS13860	COG2814	Major facilitator Superfamily
OIO62_RS13870	COG2050	protein possibly involved in aromatic compounds catabolism
OIO62_RS13885	COG1090	epimerase
OIO62_RS13905	COG0420	3'-5' exonuclease activity
OIO62_RS13930	COG0735	belongs to the Fur family
OIO62_RS13935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OIO62_RS13955	COG0121	glutamine amidotransferase
OIO62_RS13970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO62_RS13980	COG0210	DNA helicase
OIO62_RS13985	COG2885	chlorophyll binding
OIO62_RS13990	COG0204	Acyl-transferase
OIO62_RS14005	COG2894	cell division
OIO62_RS14025	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OIO62_RS14025	COG1674	ftsk spoiiie
OIO62_RS14030	COG0492	ferredoxin-NADP+ reductase activity
OIO62_RS14035	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OIO62_RS14045	COG0456	acetyltransferase
OIO62_RS14090	COG1981	membrane
OIO62_RS14105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO62_RS14105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OIO62_RS14125	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS14135	COG0657	acetylesterase activity
OIO62_RS14145	COG0473	3-isopropylmalate dehydrogenase activity
OIO62_RS14150	COG0583	DNA-binding transcription factor activity
OIO62_RS14170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO62_RS14195	COG0564	pseudouridine synthase activity
OIO62_RS14205	COG0358	DNA primase activity
OIO62_RS14220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OIO62_RS14240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OIO62_RS14270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OIO62_RS14280	COG0351	phosphomethylpyrimidine kinase
OIO62_RS14280	COG0352	thiamine-phosphate diphosphorylase activity
OIO62_RS14280	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OIO62_RS14285	COG1652	LysM domain
OIO62_RS14310	COG1399	metal-binding, possibly nucleic acid-binding protein
OIO62_RS14315	COG3101	peptidyl-lysine hydroxylation
OIO62_RS14320	COG0009	L-threonylcarbamoyladenylate synthase
OIO62_RS14325	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OIO62_RS14330	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OIO62_RS14345	COG4106	trans-aconitate 2-methyltransferase activity
OIO62_RS14360	COG0596	Alpha beta hydrolase
OIO62_RS14360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO62_RS14360	COG2226	methyltransferase
OIO62_RS14365	COG1877	trehalose-phosphatase activity
OIO62_RS14370	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
OIO62_RS14375	COG2223	nitrite transmembrane transporter activity
OIO62_RS14395	COG1196	nuclear chromosome segregation
OIO62_RS14405	COG0730	response to heat
OIO62_RS14420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OIO62_RS14480	COG0489	protein tyrosine kinase activity
OIO62_RS14490	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO62_RS14490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO62_RS14520	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OIO62_RS14525	COG2081	HI0933 family
OIO62_RS14535	COG0668	transmembrane transport
OIO62_RS14555	COG0583	DNA-binding transcription factor activity
OIO62_RS14580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OIO62_RS14585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO62_RS14615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
OIO62_RS14655	COG0745	RESPONSE REGULATOR receiver
OIO62_RS14675	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO62_RS14695	COG5290	Psort location Cytoplasmic, score
OIO62_RS14705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OIO62_RS14720	COG0583	DNA-binding transcription factor activity
OIO62_RS14730	COG0583	DNA-binding transcription factor activity
OIO62_RS14745	COG0583	DNA-binding transcription factor activity
OIO62_RS14750	COG1053	succinate dehydrogenase
OIO62_RS14765	COG1309	transcriptional regulator
OIO62_RS14770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
OIO62_RS14775	COG2814	Major facilitator Superfamily
OIO62_RS14780	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS14785	COG0583	DNA-binding transcription factor activity
OIO62_RS14790	COG1063	alcohol dehydrogenase
OIO62_RS14820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OIO62_RS14825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OIO62_RS14830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO62_RS14850	COG2132	Multicopper oxidase
OIO62_RS14860	COG0561	phosphatase activity
OIO62_RS14865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OIO62_RS14890	COG1214	PFAM Peptidase M22, glycoprotease
OIO62_RS14925	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS14960	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OIO62_RS14965	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OIO62_RS14970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OIO62_RS15030	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OIO62_RS15040	COG1846	Transcriptional regulator
OIO62_RS15045	COG1764	response to oxidative stress
OIO62_RS15085	COG0037	tRNA processing
OIO62_RS15095	COG0248	Ppx GppA phosphatase
OIO62_RS15125	COG0072	phenylalanine-tRNA ligase activity
OIO62_RS15170	COG1238	metal cluster binding
OIO62_RS15175	COG0625	glutathione transferase activity
OIO62_RS15190	COG0318	PFAM AMP-dependent synthetase and ligase
OIO62_RS15195	COG3028	Belongs to the UPF0307 family
OIO62_RS15200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OIO62_RS15220	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OIO62_RS15225	COG0617	tRNA 3'-terminal CCA addition
OIO62_RS15230	COG1555	photosystem II stabilization
OIO62_RS15235	COG3956	TIGRFAM MazG family protein
OIO62_RS15245	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OIO62_RS15265	COG0784	Response regulator, receiver
OIO62_RS15265	COG2205	protein histidine kinase activity
OIO62_RS15265	COG5002	protein histidine kinase activity
OIO62_RS15270	COG1024	Enoyl-CoA hydratase
OIO62_RS15275	COG2084	Dehydrogenase
OIO62_RS15280	COG3622	Belongs to the hyi family
OIO62_RS15310	COG0697	spore germination
OIO62_RS15320	COG2814	Major facilitator Superfamily
OIO62_RS15325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OIO62_RS15335	COG0583	DNA-binding transcription factor activity
OIO62_RS15345	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OIO62_RS15355	COG0084	hydrolase, TatD family'
OIO62_RS15370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OIO62_RS15395	COG2130	NADP-dependent
OIO62_RS15400	COG1309	transcriptional regulator
OIO62_RS15410	COG1902	pentaerythritol trinitrate reductase activity
OIO62_RS15420	COG1979	alcohol dehydrogenase
OIO62_RS15435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
OIO62_RS15450	COG0604	alcohol dehydrogenase
OIO62_RS15450	COG3321	synthase
OIO62_RS15455	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
OIO62_RS15460	COG0583	DNA-binding transcription factor activity
OIO62_RS15465	COG4221	oxidoreductase activity
OIO62_RS15580	COG0440	acetolactate synthase activity
OIO62_RS15585	COG0028	Belongs to the TPP enzyme family
OIO62_RS15610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OIO62_RS15615	COG0577	efflux transmembrane transporter activity
OIO62_RS15615	COG1136	(ABC) transporter
OIO62_RS15620	COG1538	Outer membrane efflux protein
OIO62_RS15635	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OIO62_RS15640	COG1162	GTPase activity
OIO62_RS15650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OIO62_RS15660	COG2091	lysine biosynthetic process via aminoadipic acid
OIO62_RS15690	COG1426	Protein conserved in bacteria
OIO62_RS15725	COG0793	Belongs to the peptidase S41A family
OIO62_RS15740	COG2267	carboxylic ester hydrolase activity
OIO62_RS15750	COG1012	belongs to the aldehyde dehydrogenase family
OIO62_RS15755	COG3265	gluconokinase activity
OIO62_RS15765	COG0800	Aldolase
OIO62_RS15775	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OIO62_RS15780	COG0280	phosphate acetyltransferase
OIO62_RS15780	COG0857	belongs to the CobB CobQ family
OIO62_RS15785	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO62_RS15785	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OIO62_RS15805	COG0740	serine-type endopeptidase activity
OIO62_RS15815	COG4774	siderophore transport
OIO62_RS15825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OIO62_RS15835	COG2813	Specifically methylates the guanine in position
OIO62_RS15835	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OIO62_RS15935	COG0788	formyltetrahydrofolate deformylase activity
OIO62_RS15960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO62_RS15960	COG4651	solute:proton antiporter activity
OIO62_RS15980	COG0724	RNA recognition motif
OIO62_RS15985	COG0210	DNA helicase
OIO62_RS16010	COG1733	regulation of RNA biosynthetic process
OIO62_RS16020	COG2900	Belongs to the SlyX family
OIO62_RS16025	COG0488	(ABC) transporter
OIO62_RS16045	COG1280	lysine exporter protein (LysE YggA)
OIO62_RS16050	COG1560	Kdo2-lipid A biosynthetic process
OIO62_RS16060	COG1301	dicarboxylic acid transport
OIO62_RS16115	COG0473	3-isopropylmalate dehydrogenase activity
OIO62_RS16170	COG0583	DNA-binding transcription factor activity
OIO62_RS16180	COG0625	glutathione transferase activity
OIO62_RS16185	COG2378	regulation of single-species biofilm formation
OIO62_RS16190	COG0546	phosphoglycolate phosphatase activity
OIO62_RS16200	COG1530	ribonuclease E activity
OIO62_RS16205	COG0318	PFAM AMP-dependent synthetase and ligase
OIO62_RS16220	COG0583	DNA-binding transcription factor activity
OIO62_RS16225	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS16230	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OIO62_RS16240	COG0534	Mate efflux family protein
OIO62_RS16255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OIO62_RS16280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OIO62_RS16280	COG0493	'glutamate synthase
OIO62_RS16290	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OIO62_RS16295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OIO62_RS16310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OIO62_RS16320	COG0644	oxidoreductase
OIO62_RS16320	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
OIO62_RS16330	COG0425	Belongs to the sulfur carrier protein TusA family
OIO62_RS16335	COG4535	Mg2 and Co2 transporter CorC
OIO62_RS16345	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OIO62_RS16365	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OIO62_RS16370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OIO62_RS16370	COG0475	glutathione-regulated potassium exporter activity
OIO62_RS16385	COG0484	heat shock protein binding
OIO62_RS16390	COG0789	Transcriptional regulator
OIO62_RS16395	COG0598	Magnesium transport protein CorA
OIO62_RS16410	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OIO62_RS16415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OIO62_RS16420	COG1074	ATP-dependent DNA helicase activity
OIO62_RS16425	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OIO62_RS16445	COG2226	methyltransferase
OIO62_RS16460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OIO62_RS16475	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OIO62_RS16490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OIO62_RS16490	COG2111	Na H antiporter
OIO62_RS16495	COG1006	Multisubunit Na H antiporter MnhC subunit
OIO62_RS16500	COG0651	ATP synthesis coupled electron transport
OIO62_RS16505	COG1863	multisubunit Na H antiporter MnhE subunit
OIO62_RS16510	COG2212	antiporter activity
OIO62_RS16515	COG1320	monovalent cation:proton antiporter activity
OIO62_RS16530	COG0195	Participates in both transcription termination and antitermination
OIO62_RS16580	COG0237	dephospho-CoA kinase activity
OIO62_RS16590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OIO62_RS16605	COG0497	DNA recombination
OIO62_RS16615	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OIO62_RS16645	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OIO62_RS16645	COG2169	Transcriptional regulator
OIO62_RS16650	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OIO62_RS16715	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
OIO62_RS16730	COG0326	Molecular chaperone. Has ATPase activity
OIO62_RS16745	COG2056	Na+-H+ antiporter family
OIO62_RS16750	COG0596	Alpha beta hydrolase
OIO62_RS16845	COG0546	phosphoglycolate phosphatase activity
OIO62_RS16850	COG1716	ATPase activity
OIO62_RS16880	COG2826	transposase and inactivated derivatives, IS30 family
OIO62_RS16905	COG0181	hydroxymethylbilane synthase activity
OIO62_RS16915	COG3275	phosphorelay sensor kinase activity
OIO62_RS16935	COG1538	Outer membrane efflux protein
OIO62_RS16940	COG0697	spore germination
OIO62_RS16965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OIO62_RS16970	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OIO62_RS16975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OIO62_RS16980	COG0772	Belongs to the SEDS family
OIO62_RS17005	COG4974	Belongs to the 'phage' integrase family
OIO62_RS17010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO62_RS17020	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OIO62_RS17030	COG2197	response regulator
OIO62_RS17045	COG0793	Belongs to the peptidase S41A family
OIO62_RS17050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OIO62_RS17055	COG0795	lipopolysaccharide-transporting ATPase activity
OIO62_RS17095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO62_RS17095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OIO62_RS17105	COG0004	ammonium transporteR
OIO62_RS17110	COG0347	Belongs to the P(II) protein family
OIO62_RS17160	COG0589	response to stress
OIO62_RS17165	COG0659	secondary active sulfate transmembrane transporter activity
OIO62_RS17175	COG1002	Type II restriction enzyme, methylase subunits
OIO62_RS17180	COG1061	Type III restriction enzyme res subunit
OIO62_RS17215	COG0235	Class ii aldolase
OIO62_RS17220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OIO62_RS17245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OIO62_RS17260	COG0318	PFAM AMP-dependent synthetase and ligase
OIO62_RS17270	COG0477	Major facilitator Superfamily
OIO62_RS17275	COG2860	membrane
OIO62_RS17280	COG3012	SEC-C Motif Domain Protein
OIO62_RS17285	COG1253	flavin adenine dinucleotide binding
OIO62_RS17295	COG2814	Major facilitator Superfamily
OIO62_RS17305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OIO62_RS17345	COG0655	NAD(P)H dehydrogenase (quinone) activity
OIO62_RS17360	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OIO62_RS17430	COG0758	DNA mediated transformation
OIO62_RS17440	COG0697	spore germination
OIO62_RS17445	COG1309	transcriptional regulator
OIO62_RS17460	COG0386	Belongs to the glutathione peroxidase family
OIO62_RS17525	COG1121	(ABC) transporter
OIO62_RS17530	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OIO62_RS17535	COG1280	lysine exporter protein (LysE YggA)
OIO62_RS17540	COG2837	iron assimilation
OIO62_RS17550	COG0281	malic enzyme
OIO62_RS17595	COG0519	Catalyzes the synthesis of GMP from XMP
OIO62_RS17595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OIO62_RS17600	COG4399	Belongs to the UPF0754 family
OIO62_RS17605	COG2259	Doxx family
OIO62_RS17610	COG0586	Pfam SNARE associated Golgi protein
OIO62_RS17625	COG1192	Involved in chromosome partitioning
OIO62_RS17635	COG0271	Belongs to the BolA IbaG family
OIO62_RS17655	COG2267	carboxylic ester hydrolase activity
OIO62_RS17675	COG3321	synthase
OIO62_RS17675	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
OIO62_RS17675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OIO62_RS17675	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OIO62_RS17680	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS17690	COG2197	response regulator
OIO62_RS17700	COG3916	Acyl-homoserine-lactone synthase
OIO62_RS17705	COG0477	Major facilitator Superfamily
OIO62_RS17710	COG1024	Enoyl-CoA hydratase
OIO62_RS17715	COG1024	Enoyl-CoA hydratase
OIO62_RS17720	COG1960	acyl-CoA dehydrogenase activity
OIO62_RS17725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OIO62_RS17745	COG1113	amino acid transport
OIO62_RS17750	COG1113	amino acid transport
OIO62_RS17755	COG0251	oxidation-reduction process
OIO62_RS17795	COG0564	pseudouridine synthase activity
OIO62_RS17840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OIO62_RS17855	COG1802	Transcriptional regulator
OIO62_RS17865	COG1448	Aminotransferase
OIO62_RS17870	COG0277	FAD linked oxidase domain protein
OIO62_RS17880	COG2186	Transcriptional regulator
OIO62_RS17890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OIO62_RS17900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OIO62_RS17915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OIO62_RS17920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
OIO62_RS17930	COG0438	transferase activity, transferring glycosyl groups
OIO62_RS17935	COG0438	transferase activity, transferring glycosyl groups
OIO62_RS17940	COG0463	Glycosyl transferase, family 2
OIO62_RS17940	COG1216	Glycosyl transferase, family 2
OIO62_RS17960	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OIO62_RS17970	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OIO62_RS18000	COG0728	peptidoglycan biosynthetic process
OIO62_RS18005	COG3023	N-Acetylmuramoyl-L-alanine amidase
OIO62_RS18065	COG0546	phosphoglycolate phosphatase activity
OIO62_RS18070	COG1028	Short-chain dehydrogenase reductase Sdr
OIO62_RS18090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO62_RS18095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OIO62_RS18100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OIO62_RS18105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OIO62_RS18110	COG1116	anion transmembrane transporter activity
OIO62_RS18115	COG1309	transcriptional regulator
OIO62_RS18120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OIO62_RS18130	COG0196	riboflavin kinase activity
OIO62_RS18135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OIO62_RS18145	COG1047	Peptidyl-prolyl cis-trans
OIO62_RS18185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OIO62_RS18190	COG0657	acetylesterase activity
OIO62_RS18210	COG0583	DNA-binding transcription factor activity
OIO62_RS18240	COG2951	lytic endotransglycosylase activity
OIO62_RS18245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OIO62_RS18260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OIO62_RS18270	COG0671	phosphoesterase, PA-phosphatase related
OIO62_RS18275	COG0861	Integral membrane protein TerC family
OIO62_RS18285	COG0754	glutathionylspermidine amidase activity
OIO62_RS18295	COG0402	S-adenosylhomocysteine deaminase activity
OIO62_RS18310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OIO62_RS18315	COG1230	cation diffusion facilitator family transporter
OIO62_RS18330	COG0706	membrane insertase activity
OIO62_RS18360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OIO62_RS18410	COG3586	endonuclease activity
OIO62_RS18495	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OIO62_RS18515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OIO62_RS18695	COG0358	DNA primase activity
OIO62_RS18755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OIO62_RS18795	COG0587	DNA-directed DNA polymerase activity
OIO62_RS18815	COG0587	DNA-directed DNA polymerase activity
OIO62_RS18830	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIO62_RS18830	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OIO62_RS18880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OIO62_RS18880	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OIO62_RS18885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides