locus-tag	class	description
NIY03_RS00010	COG0592	DNA-directed DNA polymerase activity
NIY03_RS00020	COG0187	DNA topoisomerase II activity
NIY03_RS00030	COG0586	Pfam SNARE associated Golgi protein
NIY03_RS00035	COG0488	(ABC) transporter
NIY03_RS00060	COG0596	Alpha beta hydrolase
NIY03_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NIY03_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIY03_RS00105	COG0733	neurotransmitter:sodium symporter activity
NIY03_RS00145	COG2233	PERMEase
NIY03_RS00160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS00195	COG2814	Major facilitator Superfamily
NIY03_RS00200	COG0656	L-ascorbic acid biosynthetic process
NIY03_RS00205	COG0583	DNA-binding transcription factor activity
NIY03_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY03_RS00225	COG1064	alcohol dehydrogenase
NIY03_RS00230	COG2818	Glycosylase
NIY03_RS00245	COG1194	a g-specific adenine glycosylase
NIY03_RS00265	COG2983	Belongs to the UPF0260 family
NIY03_RS00270	COG2133	pyrroloquinoline quinone binding
NIY03_RS00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NIY03_RS00280	COG2116	formate transmembrane transporter activity
NIY03_RS00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY03_RS00305	COG1335	isochorismatase
NIY03_RS00310	COG0385	Bile acid
NIY03_RS00315	COG0534	Mate efflux family protein
NIY03_RS00320	COG1683	Conserved Protein
NIY03_RS00340	COG0625	glutathione transferase activity
NIY03_RS00350	COG1113	amino acid transport
NIY03_RS00360	COG0523	cobalamin synthesis protein
NIY03_RS00370	COG2188	Transcriptional regulator
NIY03_RS00400	COG0010	Belongs to the arginase family
NIY03_RS00420	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NIY03_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NIY03_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIY03_RS00495	COG0753	catalase activity
NIY03_RS00545	COG0534	Mate efflux family protein
NIY03_RS00560	COG2733	membrane
NIY03_RS00575	COG2918	glutathione biosynthetic process
NIY03_RS00590	COG1388	LysM domain
NIY03_RS00590	COG1705	Flagellar rod assembly protein muramidase FlgJ
NIY03_RS00625	COG3150	esterase
NIY03_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NIY03_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY03_RS00655	COG2233	PERMEase
NIY03_RS00660	COG2351	hydroxyisourate hydrolase activity
NIY03_RS00695	COG3706	GGDEF domain
NIY03_RS00710	COG1393	Belongs to the ArsC family
NIY03_RS00715	COG0708	Exodeoxyribonuclease III
NIY03_RS00740	COG0189	ligase activity
NIY03_RS00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NIY03_RS00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIY03_RS00785	COG4942	peptidase
NIY03_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY03_RS00805	COG2119	membrane
NIY03_RS00810	COG4774	siderophore transport
NIY03_RS00815	COG0426	domain, Protein
NIY03_RS00815	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY03_RS00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NIY03_RS00860	COG1902	pentaerythritol trinitrate reductase activity
NIY03_RS00865	COG1519	Transferase
NIY03_RS00875	COG0668	transmembrane transport
NIY03_RS00885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY03_RS00890	COG1335	isochorismatase
NIY03_RS00895	COG1522	sequence-specific DNA binding
NIY03_RS00920	COG2205	protein histidine kinase activity
NIY03_RS00920	COG2198	Histidine kinase
NIY03_RS00920	COG0784	Response regulator, receiver
NIY03_RS00925	COG3162	membrane
NIY03_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY03_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY03_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIY03_RS00960	COG1309	transcriptional regulator
NIY03_RS00980	COG0351	phosphomethylpyrimidine kinase
NIY03_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY03_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
NIY03_RS00990	COG2814	Major facilitator Superfamily
NIY03_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY03_RS01015	COG1113	amino acid transport
NIY03_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY03_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS01040	COG1335	isochorismatase
NIY03_RS01080	COG2814	Major facilitator Superfamily
NIY03_RS01085	COG0583	DNA-binding transcription factor activity
NIY03_RS01130	COG1733	regulation of RNA biosynthetic process
NIY03_RS01160	COG1733	regulation of RNA biosynthetic process
NIY03_RS01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS01185	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NIY03_RS01190	COG2207	Transcriptional regulator
NIY03_RS01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIY03_RS01260	COG2329	Antibiotic biosynthesis monooxygenase
NIY03_RS01290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIY03_RS01320	COG0427	acetyl-CoA hydrolase
NIY03_RS01345	COG0659	secondary active sulfate transmembrane transporter activity
NIY03_RS01350	COG4221	oxidoreductase activity
NIY03_RS01375	COG0488	(ABC) transporter
NIY03_RS01440	COG0833	amino acid
NIY03_RS01485	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIY03_RS01490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NIY03_RS01505	COG2226	methyltransferase
NIY03_RS01555	COG0070	glutamate synthase
NIY03_RS01555	COG0067	glutamate synthase
NIY03_RS01555	COG0069	glutamate synthase activity
NIY03_RS01560	COG0493	'glutamate synthase
NIY03_RS01570	COG1704	LemA family
NIY03_RS01575	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NIY03_RS01585	COG4969	Belongs to the N-Me-Phe pilin family
NIY03_RS01590	COG3307	-O-antigen
NIY03_RS01610	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY03_RS01625	COG0194	GDP metabolic process
NIY03_RS01675	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIY03_RS01695	COG5380	lipid catabolic process
NIY03_RS01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIY03_RS01725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NIY03_RS01730	COG0277	FAD linked oxidase domain protein
NIY03_RS01740	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NIY03_RS01745	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS01760	COG1289	transmembrane transporter activity
NIY03_RS01770	COG0628	permease
NIY03_RS01775	COG1192	Involved in chromosome partitioning
NIY03_RS01805	COG0833	amino acid
NIY03_RS01810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY03_RS01815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY03_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS01865	COG0583	DNA-binding transcription factor activity
NIY03_RS01915	COG0517	IMP dehydrogenase activity
NIY03_RS01920	COG1983	PspC domain protein
NIY03_RS01930	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS01945	COG0408	coproporphyrinogen oxidase activity
NIY03_RS01965	COG0513	Belongs to the DEAD box helicase family
NIY03_RS01975	COG1127	ABC transporter
NIY03_RS01980	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NIY03_RS01990	COG2854	intermembrane phospholipid transfer
NIY03_RS02000	COG0598	Magnesium transport protein CorA
NIY03_RS02010	COG0494	nUDIX hydrolase
NIY03_RS02015	COG1040	competence protein
NIY03_RS02020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIY03_RS02040	COG1946	Acyl-CoA thioesterase
NIY03_RS02045	COG1301	dicarboxylic acid transport
NIY03_RS02060	COG1959	2 iron, 2 sulfur cluster binding
NIY03_RS02065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY03_RS02065	COG1017	nitric oxide dioxygenase activity
NIY03_RS02075	COG0433	COG0433 Predicted ATPase
NIY03_RS02080	COG0626	cystathionine gamma-synthase activity
NIY03_RS02235	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS02240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NIY03_RS02270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NIY03_RS02275	COG0339	signal peptide processing
NIY03_RS02280	COG0557	exoribonuclease II activity
NIY03_RS02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
NIY03_RS02330	COG2169	Transcriptional regulator
NIY03_RS02335	COG0697	spore germination
NIY03_RS02340	COG1295	ribonuclease BN
NIY03_RS02375	COG1702	phosphate starvation-inducible protein PhoH
NIY03_RS02385	COG0739	heme binding
NIY03_RS02385	COG0741	lytic transglycosylase activity
NIY03_RS02385	COG1196	nuclear chromosome segregation
NIY03_RS02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NIY03_RS02420	COG1183	phosphatidylcholine synthase activity
NIY03_RS02465	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS02470	COG1309	transcriptional regulator
NIY03_RS02485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY03_RS02490	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS02510	COG2969	positive regulation of protein catabolic process
NIY03_RS02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NIY03_RS02530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NIY03_RS02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NIY03_RS02540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NIY03_RS02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIY03_RS02570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY03_RS02585	COG2199	diguanylate cyclase activity
NIY03_RS02645	COG1607	acyl-coa hydrolase
NIY03_RS02675	COG3013	Belongs to the UPF0304 family
NIY03_RS02755	COG2205	protein histidine kinase activity
NIY03_RS02770	COG2132	Multicopper oxidase
NIY03_RS02795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY03_RS02845	COG0582	viral genome integration into host DNA
NIY03_RS02870	COG2350	Protein conserved in bacteria
NIY03_RS02880	COG0613	PHP domain protein
NIY03_RS02885	COG3781	membrane
NIY03_RS02895	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIY03_RS02900	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIY03_RS02910	COG1862	Preprotein translocase
NIY03_RS02940	COG0582	viral genome integration into host DNA
NIY03_RS02960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY03_RS02975	COG2205	protein histidine kinase activity
NIY03_RS02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NIY03_RS03000	COG0726	polysaccharide deacetylase
NIY03_RS03005	COG0463	Glycosyl transferase, family 2
NIY03_RS03010	COG0438	transferase activity, transferring glycosyl groups
NIY03_RS03025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NIY03_RS03075	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS03080	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS03090	COG2205	protein histidine kinase activity
NIY03_RS03095	COG0745	RESPONSE REGULATOR receiver
NIY03_RS03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NIY03_RS03120	COG2096	Adenosyltransferase
NIY03_RS03125	COG4206	TonB-dependent receptor
NIY03_RS03170	COG0285	dihydrofolate synthase activity
NIY03_RS03190	COG0450	alkyl hydroperoxide reductase
NIY03_RS03205	COG0477	Major facilitator Superfamily
NIY03_RS03210	COG1272	protein, Hemolysin III
NIY03_RS03220	COG2153	protein acetylation
NIY03_RS03240	COG0183	Belongs to the thiolase family
NIY03_RS03245	COG2207	Transcriptional regulator
NIY03_RS03265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY03_RS03285	COG0183	Belongs to the thiolase family
NIY03_RS03305	COG1690	Belongs to the RtcB family
NIY03_RS03310	COG0833	amino acid
NIY03_RS03320	COG2233	PERMEase
NIY03_RS03325	COG1217	gtp-binding protein TYPA
NIY03_RS03350	COG2094	Belongs to the DNA glycosylase MPG family
NIY03_RS03355	COG4772	TonB-dependent receptor
NIY03_RS03360	COG1902	pentaerythritol trinitrate reductase activity
NIY03_RS03375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY03_RS03380	COG0354	folic acid binding
NIY03_RS03390	COG3189	MarR family transcriptional regulator
NIY03_RS03395	COG2824	Alkylphosphonate utilization operon protein PhnA
NIY03_RS03400	COG3422	double-strand break repair
NIY03_RS03440	COG0840	transmembrane signaling receptor activity
NIY03_RS03460	COG5510	response to toxic substance
NIY03_RS03470	COG2832	Protein of unknown function (DUF454)
NIY03_RS03475	COG1376	ErfK ybiS ycfS ynhG family protein
NIY03_RS03515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIY03_RS03525	COG1289	transmembrane transporter activity
NIY03_RS03530	COG2814	Major facilitator Superfamily
NIY03_RS03550	COG1115	amino acid carrier protein
NIY03_RS03555	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY03_RS03560	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY03_RS03565	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NIY03_RS03570	COG3590	peptidase
NIY03_RS03595	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY03_RS03605	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY03_RS03610	COG1077	Cell shape determining protein MreB Mrl
NIY03_RS03615	COG1792	Involved in formation and maintenance of cell shape
NIY03_RS03620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NIY03_RS03625	COG0424	maF-like protein
NIY03_RS03630	COG1530	ribonuclease E activity
NIY03_RS03640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS03650	COG0560	Phosphoserine phosphatase
NIY03_RS03660	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS03685	COG2207	Transcriptional regulator
NIY03_RS03705	COG1113	amino acid transport
NIY03_RS03710	COG2828	Protein conserved in bacteria
NIY03_RS03715	COG0142	geranyltranstransferase activity
NIY03_RS03720	COG2315	Protein conserved in bacteria
NIY03_RS03735	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY03_RS03755	COG2194	sulfuric ester hydrolase activity
NIY03_RS03760	COG0745	RESPONSE REGULATOR receiver
NIY03_RS03765	COG0642	Histidine kinase
NIY03_RS03775	COG0004	ammonium transporteR
NIY03_RS03780	COG0583	DNA-binding transcription factor activity
NIY03_RS03800	COG0525	valine-tRNA ligase activity
NIY03_RS03810	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS03820	COG0393	Putative heavy-metal-binding
NIY03_RS03825	COG0393	Putative heavy-metal-binding
NIY03_RS03830	COG1538	Outer membrane efflux protein
NIY03_RS03840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS03845	COG0671	phosphoesterase, PA-phosphatase related
NIY03_RS03875	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NIY03_RS03890	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NIY03_RS03890	COG1648	precorrin-2 dehydrogenase activity
NIY03_RS03895	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NIY03_RS03900	COG1733	regulation of RNA biosynthetic process
NIY03_RS03910	COG0531	amino acid
NIY03_RS03925	COG0321	lipoyl(octanoyl) transferase activity
NIY03_RS03930	COG2921	Belongs to the UPF0250 family
NIY03_RS03970	COG2009	succinate dehydrogenase
NIY03_RS03975	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NIY03_RS03980	COG1053	succinate dehydrogenase
NIY03_RS03985	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NIY03_RS04010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY03_RS04030	COG2354	Protein conserved in bacteria
NIY03_RS04035	COG2321	neutral zinc metallopeptidase
NIY03_RS04055	COG2843	Capsule synthesis protein
NIY03_RS04070	COG0589	response to stress
NIY03_RS04080	COG0251	oxidation-reduction process
NIY03_RS04100	COG0505	Belongs to the CarA family
NIY03_RS04125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY03_RS04130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIY03_RS04180	COG0477	Major facilitator Superfamily
NIY03_RS04185	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIY03_RS04200	COG1597	lipid kinase activity
NIY03_RS04205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY03_RS04225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY03_RS04230	COG0584	glycerophosphoryl diester phosphodiesterase
NIY03_RS04250	COG0741	lytic transglycosylase activity
NIY03_RS04270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY03_RS04285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS04295	COG3811	Belongs to the UPF0386 family
NIY03_RS04355	COG0778	Nitroreductase
NIY03_RS04370	COG1929	Belongs to the glycerate kinase type-1 family
NIY03_RS04375	COG0243	molybdopterin cofactor binding
NIY03_RS04380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIY03_RS04385	COG3339	Conserved Protein
NIY03_RS04395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NIY03_RS04410	COG1113	amino acid transport
NIY03_RS04420	COG0019	diaminopimelate decarboxylase activity
NIY03_RS04430	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS04435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NIY03_RS04465	COG0463	Glycosyl transferase, family 2
NIY03_RS04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS04520	COG4591	ABC-type transport system involved in lipoprotein release permease component
NIY03_RS04525	COG1136	(ABC) transporter
NIY03_RS04530	COG0658	competence protein
NIY03_RS04530	COG2333	competence protein COMEC
NIY03_RS04540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIY03_RS04540	COG0616	signal peptide processing
NIY03_RS04545	COG0596	Alpha beta hydrolase
NIY03_RS04550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIY03_RS04560	COG0628	permease
NIY03_RS04595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY03_RS04615	COG0823	Involved in the tonB-independent uptake of proteins
NIY03_RS04635	COG0824	Thioesterase
NIY03_RS04640	COG1473	amidohydrolase
NIY03_RS04660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIY03_RS04660	COG0047	phosphoribosylformylglycinamidine synthase activity
NIY03_RS04685	COG1169	isochorismate synthase
NIY03_RS04695	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS04700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS04715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS04720	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY03_RS04725	COG3486	L-lysine 6-monooxygenase (NADPH) activity
NIY03_RS04730	COG0019	diaminopimelate decarboxylase activity
NIY03_RS04750	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY03_RS04755	COG4774	siderophore transport
NIY03_RS04770	COG0534	Mate efflux family protein
NIY03_RS04780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS04855	COG1024	Enoyl-CoA hydratase
NIY03_RS04860	COG1056	cytidyltransferase-related domain
NIY03_RS04860	COG1051	belongs to the nudix hydrolase family
NIY03_RS04870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIY03_RS04885	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIY03_RS04900	COG4625	pathogenesis
NIY03_RS04905	COG0583	DNA-binding transcription factor activity
NIY03_RS04910	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NIY03_RS04915	COG4208	sulfate ABC transporter
NIY03_RS04920	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NIY03_RS04930	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NIY03_RS04935	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NIY03_RS04940	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIY03_RS04960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY03_RS04970	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIY03_RS04980	COG0681	Belongs to the peptidase S26 family
NIY03_RS04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIY03_RS05005	COG1381	Involved in DNA repair and RecF pathway recombination
NIY03_RS05010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NIY03_RS05020	COG4221	oxidoreductase activity
NIY03_RS05050	COG0443	Heat shock 70 kDa protein
NIY03_RS05060	COG0436	Aminotransferase
NIY03_RS05080	COG0556	nucleotide-excision repair
NIY03_RS05135	COG2070	2-Nitropropane dioxygenase
NIY03_RS05165	COG1215	transferase activity, transferring glycosyl groups
NIY03_RS05180	COG0415	Belongs to the DNA photolyase family
NIY03_RS05190	COG1252	NADH dehydrogenase
NIY03_RS05195	COG1686	Belongs to the peptidase S11 family
NIY03_RS05210	COG1187	pseudouridine synthase activity
NIY03_RS05235	COG0477	Major facilitator Superfamily
NIY03_RS05240	COG0583	DNA-binding transcription factor activity
NIY03_RS05245	COG1823	symporter activity
NIY03_RS05255	COG0612	Peptidase, M16
NIY03_RS05280	COG0352	thiamine-phosphate diphosphorylase activity
NIY03_RS05315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY03_RS05325	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS05340	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY03_RS05345	COG0076	glutamate decarboxylase activity
NIY03_RS05355	COG1522	sequence-specific DNA binding
NIY03_RS05360	COG3961	Belongs to the TPP enzyme family
NIY03_RS05365	COG1113	amino acid transport
NIY03_RS05370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY03_RS05375	COG0573	inorganic phosphate transmembrane transporter activity
NIY03_RS05385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NIY03_RS05390	COG0616	signal peptide processing
NIY03_RS05425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIY03_RS05430	COG1686	Belongs to the peptidase S11 family
NIY03_RS05455	COG0583	DNA-binding transcription factor activity
NIY03_RS05460	COG1067	ATP-dependent peptidase activity
NIY03_RS05485	COG4943	cyclic-guanylate-specific phosphodiesterase activity
NIY03_RS05505	COG1966	Carbon starvation protein
NIY03_RS05510	COG2879	small protein
NIY03_RS05565	COG1335	isochorismatase
NIY03_RS05570	COG0583	DNA-binding transcription factor activity
NIY03_RS05585	COG0596	Alpha beta hydrolase
NIY03_RS05595	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY03_RS05640	COG1741	Belongs to the pirin family
NIY03_RS05650	COG2964	Protein conserved in bacteria
NIY03_RS05665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS05670	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY03_RS05675	COG4605	iron ion homeostasis
NIY03_RS05680	COG4604	ABC transporter, ATP-binding protein
NIY03_RS05685	COG4607	ABC-type enterochelin transport system periplasmic component
NIY03_RS05690	COG4774	siderophore transport
NIY03_RS05700	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY03_RS05705	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY03_RS05710	COG1535	isochorismatase
NIY03_RS05710	COG3433	isochorismatase activity
NIY03_RS05720	COG1132	(ABC) transporter
NIY03_RS05725	COG1132	(ABC) transporter
NIY03_RS05730	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY03_RS05755	COG3739	integral membrane protein
NIY03_RS05775	COG0302	gtp cyclohydrolase
NIY03_RS05785	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NIY03_RS05815	COG0308	aminopeptidase N
NIY03_RS05820	COG0512	Glutamine amidotransferase of anthranilate synthase
NIY03_RS05835	COG0174	glutamine synthetase
NIY03_RS05845	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NIY03_RS05880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIY03_RS05885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIY03_RS05890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY03_RS05910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY03_RS05915	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NIY03_RS05920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NIY03_RS05935	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS05940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY03_RS05945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY03_RS05955	COG2223	nitrite transmembrane transporter activity
NIY03_RS05965	COG0024	Methionine aminopeptidase
NIY03_RS05970	COG0052	Belongs to the universal ribosomal protein uS2 family
NIY03_RS05985	COG2207	Transcriptional regulator
NIY03_RS06010	COG2951	lytic endotransglycosylase activity
NIY03_RS06015	COG0772	Belongs to the SEDS family
NIY03_RS06030	COG0842	Transport permease protein
NIY03_RS06035	COG1131	(ABC) transporter
NIY03_RS06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS06095	COG4215	(ABC) transporter
NIY03_RS06100	COG4160	amino acid transport
NIY03_RS06105	COG4598	ABC transporter
NIY03_RS06115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY03_RS06120	COG0826	peptidase U32
NIY03_RS06125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY03_RS06140	COG1720	tRNA m6t6A37 methyltransferase activity
NIY03_RS06150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIY03_RS06165	COG0642	Histidine kinase
NIY03_RS06175	COG0494	nUDIX hydrolase
NIY03_RS06185	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NIY03_RS06190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIY03_RS06195	COG3139	Protein of unknown function (DUF1315)
NIY03_RS06200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIY03_RS06205	COG1301	dicarboxylic acid transport
NIY03_RS06210	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS06215	COG2819	hydrolase of the alpha beta superfamily
NIY03_RS06225	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NIY03_RS06235	COG2195	Cleaves the N-terminal amino acid of tripeptides
NIY03_RS06255	COG1690	Belongs to the RtcB family
NIY03_RS06260	COG1234	tRNA 3'-trailer cleavage
NIY03_RS06265	COG4650	regulator
NIY03_RS06295	COG2363	Small membrane protein
NIY03_RS06320	COG0513	Belongs to the DEAD box helicase family
NIY03_RS06330	COG0778	Nitroreductase
NIY03_RS06360	COG1286	toxin biosynthetic process
NIY03_RS06385	COG4783	chaperone-mediated protein folding
NIY03_RS06390	COG1610	YqeY-like protein
NIY03_RS06420	COG0515	serine threonine protein kinase
NIY03_RS06420	COG2815	serine threonine protein kinase
NIY03_RS06510	COG0477	Major facilitator Superfamily
NIY03_RS06515	COG1051	belongs to the nudix hydrolase family
NIY03_RS06545	COG2995	paraquat-inducible protein a
NIY03_RS06550	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NIY03_RS06550	COG3008	intermembrane lipid transfer
NIY03_RS06565	COG1794	racemase activity, acting on amino acids and derivatives
NIY03_RS06595	COG1301	dicarboxylic acid transport
NIY03_RS06605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY03_RS06610	COG2011	ABC-type metal ion transport system permease component
NIY03_RS06615	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY03_RS06620	COG1464	Belongs to the NlpA lipoprotein family
NIY03_RS06625	COG0151	Belongs to the GarS family
NIY03_RS06630	COG0138	bifunctional purine biosynthesis protein purh
NIY03_RS06635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NIY03_RS06665	COG2308	Evidence 4 Homologs of previously reported genes of
NIY03_RS06675	COG1305	Transglutaminase-like
NIY03_RS06685	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIY03_RS06690	COG0305	Participates in initiation and elongation during chromosome replication
NIY03_RS06715	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NIY03_RS06725	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIY03_RS06730	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NIY03_RS06755	COG1649	PFAM Uncharacterised BCR, COG1649
NIY03_RS06755	COG0726	polysaccharide deacetylase
NIY03_RS06760	COG1215	transferase activity, transferring glycosyl groups
NIY03_RS06765	COG3658	cytochrome
NIY03_RS06775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY03_RS06790	COG0583	DNA-binding transcription factor activity
NIY03_RS06820	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS06825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY03_RS06830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY03_RS06845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIY03_RS06855	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NIY03_RS06860	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NIY03_RS06865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NIY03_RS06870	COG2205	protein histidine kinase activity
NIY03_RS06875	COG0745	RESPONSE REGULATOR receiver
NIY03_RS06880	COG0174	glutamine synthetase
NIY03_RS06900	COG0729	surface antigen
NIY03_RS06925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY03_RS06930	COG2814	Major facilitator Superfamily
NIY03_RS06945	COG0583	DNA-binding transcription factor activity
NIY03_RS06960	COG1187	pseudouridine synthase activity
NIY03_RS06980	COG0802	atpase or kinase
NIY03_RS06985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIY03_RS06995	COG1923	regulation of RNA biosynthetic process
NIY03_RS07000	COG0697	spore germination
NIY03_RS07025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY03_RS07030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY03_RS07030	COG0519	Catalyzes the synthesis of GMP from XMP
NIY03_RS07035	COG4302	ethanolamine ammonia-lyase activity
NIY03_RS07040	COG4303	Ethanolamine ammonia lyase large subunit
NIY03_RS07045	COG0531	amino acid
NIY03_RS07065	COG1454	alcohol dehydrogenase
NIY03_RS07070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY03_RS07095	COG0308	aminopeptidase N
NIY03_RS07135	COG1605	Chorismate mutase
NIY03_RS07155	COG1309	transcriptional regulator
NIY03_RS07165	COG0668	transmembrane transport
NIY03_RS07195	COG4773	Receptor
NIY03_RS07215	COG0488	(ABC) transporter
NIY03_RS07220	COG0589	response to stress
NIY03_RS07240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NIY03_RS07250	COG3135	benzoate transporter
NIY03_RS07255	COG1522	sequence-specific DNA binding
NIY03_RS07265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIY03_RS07270	COG0583	DNA-binding transcription factor activity
NIY03_RS07280	COG0183	Belongs to the thiolase family
NIY03_RS07290	COG2030	dehydratase
NIY03_RS07295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY03_RS07310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIY03_RS07320	COG0824	Thioesterase
NIY03_RS07325	COG1454	alcohol dehydrogenase
NIY03_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIY03_RS07355	COG0069	glutamate synthase activity
NIY03_RS07500	COG3617	BRO family, N-terminal domain
NIY03_RS07540	COG5410	chromosome segregation
NIY03_RS07645	COG1598	PFAM Uncharacterised protein family UPF0150
NIY03_RS07715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY03_RS07730	COG2814	Major facilitator Superfamily
NIY03_RS07745	COG0511	ligase activity, forming carbon-carbon bonds
NIY03_RS07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY03_RS07765	COG1116	anion transmembrane transporter activity
NIY03_RS07770	COG0745	RESPONSE REGULATOR receiver
NIY03_RS07780	COG2146	nitrite reductase [NAD(P)H] activity
NIY03_RS07780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY03_RS07785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY03_RS07790	COG0243	molybdopterin cofactor binding
NIY03_RS07800	COG0243	molybdopterin cofactor binding
NIY03_RS07805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIY03_RS07820	COG0315	cyclic pyranopterin monophosphate synthase activity
NIY03_RS07820	COG0521	Mo-molybdopterin cofactor biosynthetic process
NIY03_RS07825	COG0303	'Molybdopterin
NIY03_RS07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY03_RS07840	COG0697	spore germination
NIY03_RS07860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NIY03_RS07865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY03_RS07920	COG2204	response regulator
NIY03_RS07925	COG3852	Histidine kinase
NIY03_RS07950	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIY03_RS07955	COG0575	Belongs to the CDS family
NIY03_RS07970	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY03_RS07990	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY03_RS08005	COG2137	regulation of response to DNA damage stimulus
NIY03_RS08015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NIY03_RS08020	COG1011	Hydrolase
NIY03_RS08045	COG1522	sequence-specific DNA binding
NIY03_RS08055	COG1113	amino acid transport
NIY03_RS08075	COG0659	secondary active sulfate transmembrane transporter activity
NIY03_RS08080	COG2135	peptidase activity
NIY03_RS08095	COG3300	MHYT domain
NIY03_RS08095	COG5001	Diguanylate cyclase
NIY03_RS08110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY03_RS08110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NIY03_RS08110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY03_RS08115	COG1105	Belongs to the carbohydrate kinase PfkB family
NIY03_RS08120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIY03_RS08120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY03_RS08150	COG0024	Methionine aminopeptidase
NIY03_RS08155	COG0583	DNA-binding transcription factor activity
NIY03_RS08165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NIY03_RS08170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY03_RS08175	COG0516	GMP reductase activity
NIY03_RS08175	COG0517	IMP dehydrogenase activity
NIY03_RS08200	COG0552	protein localization to endoplasmic reticulum
NIY03_RS08210	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NIY03_RS08225	COG4890	Cyd operon protein YbgT
NIY03_RS08230	COG1294	oxidase, subunit
NIY03_RS08245	COG1585	Membrane protein implicated in regulation of membrane protease activity
NIY03_RS08255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIY03_RS08260	COG4774	siderophore transport
NIY03_RS08275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NIY03_RS08280	COG0569	domain protein
NIY03_RS08285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY03_RS08315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NIY03_RS08320	COG0542	response to heat
NIY03_RS08345	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY03_RS08345	COG1902	pentaerythritol trinitrate reductase activity
NIY03_RS08390	COG2323	membrane
NIY03_RS08395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIY03_RS08405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY03_RS08410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY03_RS08415	COG0183	Belongs to the thiolase family
NIY03_RS08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIY03_RS08425	COG0596	Alpha beta hydrolase
NIY03_RS08430	COG2271	Major facilitator Superfamily
NIY03_RS08435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY03_RS08440	COG3485	protocatechuate 3,4-dioxygenase
NIY03_RS08445	COG3485	protocatechuate 3,4-dioxygenase
NIY03_RS08450	COG0710	3-dehydroquinate dehydratase activity
NIY03_RS08455	COG3420	alginic acid biosynthetic process
NIY03_RS08460	COG3659	wide pore channel activity
NIY03_RS08465	COG4993	Dehydrogenase
NIY03_RS08475	COG2391	methyltransferase activity
NIY03_RS08490	COG1414	Transcriptional regulator
NIY03_RS08495	COG0583	DNA-binding transcription factor activity
NIY03_RS08500	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS08525	COG2814	Major facilitator Superfamily
NIY03_RS08535	COG0154	amidase activity
NIY03_RS08555	COG4638	Rieske (2fe-2S)
NIY03_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS08575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY03_RS08585	COG3733	amine oxidase
NIY03_RS08595	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS08605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY03_RS08610	COG0183	Belongs to the thiolase family
NIY03_RS08615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY03_RS08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY03_RS08630	COG4829	muconolactone delta-isomerase
NIY03_RS08635	COG4948	Mandelate Racemase Muconate Lactonizing
NIY03_RS08640	COG0583	DNA-binding transcription factor activity
NIY03_RS08650	COG2186	Transcriptional regulator
NIY03_RS08670	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS08685	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY03_RS08685	COG1902	pentaerythritol trinitrate reductase activity
NIY03_RS08695	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIY03_RS08705	COG0789	Transcriptional regulator
NIY03_RS08730	COG1309	transcriptional regulator
NIY03_RS08735	COG0583	DNA-binding transcription factor activity
NIY03_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS08745	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS08750	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS08760	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS08770	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS08845	COG2188	Transcriptional regulator
NIY03_RS08860	COG0583	DNA-binding transcription factor activity
NIY03_RS08875	COG1566	PFAM secretion protein HlyD family protein
NIY03_RS08890	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS08895	COG0129	dihydroxy-acid dehydratase activity
NIY03_RS08905	COG0583	DNA-binding transcription factor activity
NIY03_RS08910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY03_RS08920	COG2084	Dehydrogenase
NIY03_RS08925	COG2207	Transcriptional regulator
NIY03_RS08930	COG1064	alcohol dehydrogenase
NIY03_RS08940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY03_RS08945	COG1120	ATPase activity
NIY03_RS09040	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NIY03_RS09075	COG2856	Zn peptidase
NIY03_RS09130	COG2207	Transcriptional regulator
NIY03_RS09145	COG2205	protein histidine kinase activity
NIY03_RS09150	COG0745	RESPONSE REGULATOR receiver
NIY03_RS09155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS09160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY03_RS09240	COG3539	Fimbrial protein
NIY03_RS09265	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NIY03_RS09275	COG0753	catalase activity
NIY03_RS09290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY03_RS09350	COG1535	isochorismatase
NIY03_RS09350	COG3433	isochorismatase activity
NIY03_RS09355	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS09360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NIY03_RS09365	COG4149	molybdate abc transporter
NIY03_RS09370	COG0725	ABC transporter, periplasmic molybdate-binding protein
NIY03_RS09380	COG4638	Rieske (2fe-2S)
NIY03_RS09385	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY03_RS09390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY03_RS09390	COG0543	2 iron, 2 sulfur cluster binding
NIY03_RS09405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY03_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS09430	COG2207	Transcriptional regulator
NIY03_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS09440	COG2610	gluconate transmembrane transporter activity
NIY03_RS09450	COG1309	transcriptional regulator
NIY03_RS09475	COG0583	DNA-binding transcription factor activity
NIY03_RS09490	COG2031	fatty acid transporter
NIY03_RS09495	COG0183	Belongs to the thiolase family
NIY03_RS09500	COG0583	DNA-binding transcription factor activity
NIY03_RS09505	COG0583	DNA-binding transcription factor activity
NIY03_RS09520	COG1027	Aspartate ammonia-lyase
NIY03_RS09530	COG0477	Major facilitator Superfamily
NIY03_RS09550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY03_RS09555	COG4521	taurine ABC transporter
NIY03_RS09570	COG2188	Transcriptional regulator
NIY03_RS09580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIY03_RS09585	COG1733	regulation of RNA biosynthetic process
NIY03_RS09590	COG2207	Transcriptional regulator
NIY03_RS09590	COG3708	Transcriptional regulator
NIY03_RS09605	COG0730	response to heat
NIY03_RS09620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY03_RS09620	COG3453	Protein conserved in bacteria
NIY03_RS09630	COG3781	membrane
NIY03_RS09635	COG1063	alcohol dehydrogenase
NIY03_RS09645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY03_RS09650	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY03_RS09655	COG0022	dehydrogenase e1 component
NIY03_RS09660	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NIY03_RS09665	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY03_RS09680	COG3706	GGDEF domain
NIY03_RS09695	COG0133	tryptophan synthase activity
NIY03_RS09705	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY03_RS09735	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
NIY03_RS09740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIY03_RS09765	COG2226	methyltransferase
NIY03_RS09820	COG0842	Transport permease protein
NIY03_RS09825	COG0842	Transport permease protein
NIY03_RS09830	COG1131	(ABC) transporter
NIY03_RS09845	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY03_RS09850	COG4773	Receptor
NIY03_RS09870	COG0730	response to heat
NIY03_RS09875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIY03_RS09890	COG0406	alpha-ribazole phosphatase activity
NIY03_RS09895	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NIY03_RS09910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY03_RS09940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY03_RS09950	COG4264	IucA IucC family
NIY03_RS09955	COG4264	IucA IucC family
NIY03_RS09960	COG2814	Major facilitator Superfamily
NIY03_RS09975	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIY03_RS09990	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS09995	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS10000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY03_RS10005	COG2207	Transcriptional regulator
NIY03_RS10010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY03_RS10015	COG0776	regulation of translation
NIY03_RS10040	COG0822	iron-sulfur transferase activity
NIY03_RS10045	COG0316	Belongs to the HesB IscA family
NIY03_RS10075	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIY03_RS10095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY03_RS10100	COG0702	epimerase
NIY03_RS10135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIY03_RS10145	COG0339	signal peptide processing
NIY03_RS10195	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NIY03_RS10315	COG4695	Portal protein
NIY03_RS10480	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NIY03_RS10510	COG0776	regulation of translation
NIY03_RS10575	COG0084	hydrolase, TatD family'
NIY03_RS10595	COG1663	tetraacyldisaccharide 4'-kinase activity
NIY03_RS10600	COG1132	(ABC) transporter
NIY03_RS10610	COG0811	peptide transport
NIY03_RS10615	COG1475	DNA binding
NIY03_RS10620	COG1192	Involved in chromosome partitioning
NIY03_RS10630	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NIY03_RS10645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY03_RS10650	COG0191	fructose-bisphosphate aldolase activity
NIY03_RS10670	COG0424	maF-like protein
NIY03_RS10675	COG2850	peptidyl-arginine hydroxylation
NIY03_RS10685	COG0640	Transcriptional regulator
NIY03_RS10695	COG3619	membrane
NIY03_RS10700	COG3122	Protein conserved in bacteria
NIY03_RS10705	COG1132	(ABC) transporter
NIY03_RS10725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIY03_RS10730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY03_RS10740	COG0506	proline dehydrogenase activity
NIY03_RS10740	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY03_RS10740	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY03_RS10745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIY03_RS10760	COG3698	Phosphodiester glycosidase
NIY03_RS10770	COG2353	YceI-like domain
NIY03_RS10780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIY03_RS10825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIY03_RS10825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NIY03_RS10850	COG3539	Fimbrial protein
NIY03_RS10855	COG3121	Chaperone
NIY03_RS10880	COG0697	spore germination
NIY03_RS10890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY03_RS10900	COG0583	DNA-binding transcription factor activity
NIY03_RS10920	COG1309	transcriptional regulator
NIY03_RS10935	COG1522	sequence-specific DNA binding
NIY03_RS10945	COG1126	abc transporter atp-binding protein
NIY03_RS10950	COG0765	amino acid transport
NIY03_RS10955	COG0765	amino acid transport
NIY03_RS10985	COG1464	Belongs to the NlpA lipoprotein family
NIY03_RS10995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY03_RS11000	COG2011	ABC-type metal ion transport system permease component
NIY03_RS11005	COG0012	GTP binding
NIY03_RS11030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY03_RS11070	COG0386	Belongs to the glutathione peroxidase family
NIY03_RS11080	COG0436	Aminotransferase
NIY03_RS11085	COG1301	dicarboxylic acid transport
NIY03_RS11120	COG3634	alkyl hydroperoxide reductase activity
NIY03_RS11135	COG0583	DNA-binding transcription factor activity
NIY03_RS11140	COG0798	PFAM Bile acid sodium symporter
NIY03_RS11145	COG0640	Transcriptional regulator
NIY03_RS11160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIY03_RS11170	COG0583	DNA-binding transcription factor activity
NIY03_RS11180	COG1953	Uracil, thiamine, allantoin
NIY03_RS11190	COG2175	clavaminate synthase activity
NIY03_RS11195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY03_RS11200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NIY03_RS11205	COG4521	taurine ABC transporter
NIY03_RS11215	COG0477	Major facilitator Superfamily
NIY03_RS11235	COG1271	oxidase subunit
NIY03_RS11240	COG1294	oxidase, subunit
NIY03_RS11250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY03_RS11270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NIY03_RS11290	COG3052	prosthetic group binding
NIY03_RS11295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NIY03_RS11305	COG0583	DNA-binding transcription factor activity
NIY03_RS11315	COG2814	Major facilitator Superfamily
NIY03_RS11330	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY03_RS11335	COG1346	cytolysis
NIY03_RS11345	COG0583	DNA-binding transcription factor activity
NIY03_RS11350	COG0625	glutathione transferase activity
NIY03_RS11355	COG0625	glutathione transferase activity
NIY03_RS11360	COG0583	DNA-binding transcription factor activity
NIY03_RS11375	COG1045	serine acetyltransferase
NIY03_RS11380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY03_RS11385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIY03_RS11410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY03_RS11415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY03_RS11425	COG0765	amino acid transport
NIY03_RS11430	COG0765	amino acid transport
NIY03_RS11450	COG2205	protein histidine kinase activity
NIY03_RS11450	COG0784	Response regulator, receiver
NIY03_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS11540	COG0583	DNA-binding transcription factor activity
NIY03_RS11560	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS11565	COG1309	transcriptional regulator
NIY03_RS11570	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS11575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY03_RS11580	COG1024	Enoyl-CoA hydratase
NIY03_RS11585	COG4770	biotin carboxylase activity
NIY03_RS11595	COG0583	DNA-binding transcription factor activity
NIY03_RS11615	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY03_RS11620	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NIY03_RS11635	COG3842	ATPase activity
NIY03_RS11640	COG1840	ABC-type Fe3 transport system, periplasmic component
NIY03_RS11655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY03_RS11660	COG1414	Transcriptional regulator
NIY03_RS11670	COG0583	DNA-binding transcription factor activity
NIY03_RS11675	COG3038	cytochrome b561
NIY03_RS11680	COG0753	catalase activity
NIY03_RS11715	COG2050	protein possibly involved in aromatic compounds catabolism
NIY03_RS11725	COG3327	negative regulation of DNA-templated transcription, initiation
NIY03_RS11730	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NIY03_RS11735	COG0183	Belongs to the thiolase family
NIY03_RS11740	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY03_RS11745	COG1024	Enoyl-CoA hydratase
NIY03_RS11750	COG1024	Enoyl-CoA hydratase
NIY03_RS11755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY03_RS11760	COG2151	metal-sulfur cluster biosynthetic enzyme
NIY03_RS11765	COG3396	Phenylacetate-CoA oxygenase
NIY03_RS11770	COG3460	Phenylacetate-CoA oxygenase
NIY03_RS11775	COG3396	Phenylacetate-CoA oxygenase
NIY03_RS11780	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS11780	COG2030	dehydratase
NIY03_RS11785	COG1760	l-serine dehydratase
NIY03_RS11790	COG0531	amino acid
NIY03_RS11795	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS11820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY03_RS11840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY03_RS11850	COG0789	Transcriptional regulator
NIY03_RS11860	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIY03_RS11875	COG2807	transmembrane transport
NIY03_RS11880	COG0590	tRNA wobble adenosine to inosine editing
NIY03_RS11990	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY03_RS12015	COG1116	anion transmembrane transporter activity
NIY03_RS12020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY03_RS12030	COG0864	Transcriptional regulator
NIY03_RS12045	COG1733	regulation of RNA biosynthetic process
NIY03_RS12050	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS12055	COG0439	Biotin carboxylase
NIY03_RS12070	COG1063	alcohol dehydrogenase
NIY03_RS12080	COG1309	transcriptional regulator
NIY03_RS12090	COG0038	chloride channel
NIY03_RS12095	COG4770	biotin carboxylase activity
NIY03_RS12115	COG1914	H( )-stimulated, divalent metal cation uptake system
NIY03_RS12120	COG0583	DNA-binding transcription factor activity
NIY03_RS12155	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY03_RS12175	COG2814	Major facilitator Superfamily
NIY03_RS12195	COG0598	Magnesium transport protein CorA
NIY03_RS12200	COG1560	Kdo2-lipid A biosynthetic process
NIY03_RS12215	COG1522	sequence-specific DNA binding
NIY03_RS12230	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NIY03_RS12240	COG4122	O-methyltransferase activity
NIY03_RS12270	COG1538	Outer membrane efflux protein
NIY03_RS12275	COG1137	ATPase activity
NIY03_RS12280	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NIY03_RS12290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NIY03_RS12295	COG0517	IMP dehydrogenase activity
NIY03_RS12295	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NIY03_RS12330	COG2814	Major facilitator Superfamily
NIY03_RS12365	COG1278	Cold shock
NIY03_RS12370	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS12400	COG1570	exodeoxyribonuclease VII activity
NIY03_RS12450	COG0583	DNA-binding transcription factor activity
NIY03_RS12455	COG4638	Rieske (2fe-2S)
NIY03_RS12460	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY03_RS12465	COG0543	2 iron, 2 sulfur cluster binding
NIY03_RS12465	COG0633	Ferredoxin
NIY03_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS12475	COG3135	benzoate transporter
NIY03_RS12480	COG2814	Major facilitator Superfamily
NIY03_RS12495	COG1643	Atp-dependent helicase
NIY03_RS12500	COG0450	alkyl hydroperoxide reductase
NIY03_RS12510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NIY03_RS12520	COG3634	alkyl hydroperoxide reductase activity
NIY03_RS12540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NIY03_RS12545	COG0625	glutathione transferase activity
NIY03_RS12555	COG2885	chlorophyll binding
NIY03_RS12590	COG0542	response to heat
NIY03_RS12605	COG1765	OsmC-like protein
NIY03_RS12620	COG0667	Aldo Keto reductase
NIY03_RS12635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIY03_RS12655	COG0582	viral genome integration into host DNA
NIY03_RS12790	COG3566	protein conserved in bacteria
NIY03_RS12810	COG3567	Phage-associated protein, HI1409 family
NIY03_RS12815	COG5410	chromosome segregation
NIY03_RS12890	COG4197	protein conserved in bacteria, prophage-related
NIY03_RS12895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY03_RS12945	COG0527	aspartate kinase activity
NIY03_RS12955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIY03_RS12965	COG3038	cytochrome b561
NIY03_RS12970	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIY03_RS12975	COG2252	PERMEase
NIY03_RS12985	COG2072	flavoprotein involved in K transport
NIY03_RS13000	COG1741	Belongs to the pirin family
NIY03_RS13005	COG1309	transcriptional regulator
NIY03_RS13015	COG0300	oxidoreductase activity
NIY03_RS13020	COG2072	flavoprotein involved in K transport
NIY03_RS13025	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NIY03_RS13070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY03_RS13085	COG2814	Major facilitator Superfamily
NIY03_RS13090	COG1024	Enoyl-CoA hydratase
NIY03_RS13095	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS13105	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS13130	COG2186	Transcriptional regulator
NIY03_RS13135	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS13145	COG4948	Mandelate Racemase Muconate Lactonizing
NIY03_RS13150	COG2271	Major facilitator Superfamily
NIY03_RS13155	COG2721	sulfolactate sulfo-lyase activity
NIY03_RS13160	COG0697	spore germination
NIY03_RS13190	COG1113	amino acid transport
NIY03_RS13210	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS13230	COG0531	amino acid
NIY03_RS13240	COG1113	amino acid transport
NIY03_RS13285	COG0583	DNA-binding transcription factor activity
NIY03_RS13295	COG0251	oxidation-reduction process
NIY03_RS13345	COG1902	pentaerythritol trinitrate reductase activity
NIY03_RS13345	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY03_RS13360	COG3706	GGDEF domain
NIY03_RS13360	COG5001	Diguanylate cyclase
NIY03_RS13360	COG2203	Gaf domain
NIY03_RS13360	COG4251	negative regulation of phosphorylation
NIY03_RS13370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY03_RS13390	COG4172	Belongs to the ABC transporter superfamily
NIY03_RS13395	COG4239	(ABC) transporter, permease
NIY03_RS13400	COG4174	ABC transporter (Permease)
NIY03_RS13410	COG1388	LysM domain
NIY03_RS13410	COG0741	lytic transglycosylase activity
NIY03_RS13410	COG1388	LysM domain
NIY03_RS13410	COG0741	lytic transglycosylase activity
NIY03_RS13415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY03_RS13455	COG0583	DNA-binding transcription factor activity
NIY03_RS13460	COG1279	arginine transmembrane transporter activity
NIY03_RS13480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY03_RS13485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY03_RS13490	COG0006	proline dipeptidase activity
NIY03_RS13530	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIY03_RS13555	COG3384	dioxygenase
NIY03_RS13565	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY03_RS13570	COG2878	Part of a membrane complex involved in electron transport
NIY03_RS13575	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIY03_RS13600	COG0768	penicillin binding
NIY03_RS13605	COG0742	ribosomal rna small subunit methyltransferase
NIY03_RS13620	COG0830	nickel cation binding
NIY03_RS13630	COG0804	urea catabolic process
NIY03_RS13675	COG1253	flavin adenine dinucleotide binding
NIY03_RS13680	COG2851	Citrate transporter
NIY03_RS13730	COG1773	rubredoxin
NIY03_RS13735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY03_RS13745	COG0583	DNA-binding transcription factor activity
NIY03_RS13775	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NIY03_RS13780	COG4181	ATPase activity
NIY03_RS13825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY03_RS13845	COG0306	phosphate transporter
NIY03_RS13860	COG3958	Transketolase
NIY03_RS13865	COG3959	Transketolase, thiamine diphosphate binding domain
NIY03_RS13870	COG2271	Major facilitator Superfamily
NIY03_RS13875	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS13880	COG0583	DNA-binding transcription factor activity
NIY03_RS13900	COG2223	nitrite transmembrane transporter activity
NIY03_RS13905	COG2207	Transcriptional regulator
NIY03_RS13910	COG2066	Belongs to the glutaminase family
NIY03_RS13915	COG0242	peptide deformylase activity
NIY03_RS13920	COG0477	Major facilitator Superfamily
NIY03_RS13930	COG0028	Belongs to the TPP enzyme family
NIY03_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS13950	COG2267	carboxylic ester hydrolase activity
NIY03_RS13960	COG2271	Major facilitator Superfamily
NIY03_RS13965	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY03_RS13975	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS13995	COG1414	Transcriptional regulator
NIY03_RS14010	COG1024	Enoyl-CoA hydratase
NIY03_RS14020	COG1215	transferase activity, transferring glycosyl groups
NIY03_RS14025	COG0726	polysaccharide deacetylase
NIY03_RS14025	COG1649	PFAM Uncharacterised BCR, COG1649
NIY03_RS14035	COG4681	YaeQ
NIY03_RS14045	COG0523	cobalamin synthesis protein
NIY03_RS14055	COG1607	acyl-coa hydrolase
NIY03_RS14065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY03_RS14070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY03_RS14075	COG1309	transcriptional regulator
NIY03_RS14100	COG2040	homocysteine
NIY03_RS14105	COG0531	amino acid
NIY03_RS14130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY03_RS14135	COG0477	Major facilitator Superfamily
NIY03_RS14175	COG0405	Gamma-glutamyltransferase
NIY03_RS14180	COG2814	Major facilitator Superfamily
NIY03_RS14190	COG2050	protein possibly involved in aromatic compounds catabolism
NIY03_RS14205	COG1090	epimerase
NIY03_RS14225	COG0420	3'-5' exonuclease activity
NIY03_RS14250	COG0735	belongs to the Fur family
NIY03_RS14255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY03_RS14275	COG0121	glutamine amidotransferase
NIY03_RS14290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY03_RS14300	COG0210	DNA helicase
NIY03_RS14305	COG2885	chlorophyll binding
NIY03_RS14310	COG0204	Acyl-transferase
NIY03_RS14325	COG2894	cell division
NIY03_RS14340	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS14345	COG1674	ftsk spoiiie
NIY03_RS14345	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIY03_RS14350	COG0492	ferredoxin-NADP+ reductase activity
NIY03_RS14355	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NIY03_RS14365	COG0456	acetyltransferase
NIY03_RS14410	COG1981	membrane
NIY03_RS14425	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NIY03_RS14425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY03_RS14445	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS14455	COG0657	acetylesterase activity
NIY03_RS14465	COG0473	3-isopropylmalate dehydrogenase activity
NIY03_RS14470	COG0583	DNA-binding transcription factor activity
NIY03_RS14490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY03_RS14515	COG0564	pseudouridine synthase activity
NIY03_RS14525	COG0358	DNA primase activity
NIY03_RS14540	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NIY03_RS14570	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY03_RS14600	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIY03_RS14610	COG0352	thiamine-phosphate diphosphorylase activity
NIY03_RS14610	COG0351	phosphomethylpyrimidine kinase
NIY03_RS14610	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY03_RS14615	COG1652	LysM domain
NIY03_RS14640	COG1399	metal-binding, possibly nucleic acid-binding protein
NIY03_RS14645	COG3101	peptidyl-lysine hydroxylation
NIY03_RS14650	COG0009	L-threonylcarbamoyladenylate synthase
NIY03_RS14655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIY03_RS14660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIY03_RS14675	COG4106	trans-aconitate 2-methyltransferase activity
NIY03_RS14690	COG0596	Alpha beta hydrolase
NIY03_RS14690	COG2226	methyltransferase
NIY03_RS14690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY03_RS14695	COG1877	trehalose-phosphatase activity
NIY03_RS14700	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NIY03_RS14705	COG2223	nitrite transmembrane transporter activity
NIY03_RS14725	COG1196	nuclear chromosome segregation
NIY03_RS14735	COG0730	response to heat
NIY03_RS14750	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIY03_RS14760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY03_RS14810	COG0489	protein tyrosine kinase activity
NIY03_RS14820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY03_RS14820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY03_RS14850	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NIY03_RS14855	COG2081	HI0933 family
NIY03_RS14865	COG0668	transmembrane transport
NIY03_RS14885	COG0583	DNA-binding transcription factor activity
NIY03_RS14910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NIY03_RS14915	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY03_RS14945	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIY03_RS14985	COG0745	RESPONSE REGULATOR receiver
NIY03_RS15005	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIY03_RS15060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY03_RS15075	COG0583	DNA-binding transcription factor activity
NIY03_RS15105	COG0583	DNA-binding transcription factor activity
NIY03_RS15120	COG0583	DNA-binding transcription factor activity
NIY03_RS15125	COG1053	succinate dehydrogenase
NIY03_RS15135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NIY03_RS15140	COG2814	Major facilitator Superfamily
NIY03_RS15145	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS15150	COG0583	DNA-binding transcription factor activity
NIY03_RS15155	COG1063	alcohol dehydrogenase
NIY03_RS15185	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIY03_RS15190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIY03_RS15195	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY03_RS15215	COG2132	Multicopper oxidase
NIY03_RS15225	COG0561	phosphatase activity
NIY03_RS15230	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NIY03_RS15255	COG1214	PFAM Peptidase M22, glycoprotease
NIY03_RS15305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIY03_RS15315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIY03_RS15320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NIY03_RS15325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIY03_RS15385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY03_RS15395	COG1846	Transcriptional regulator
NIY03_RS15400	COG1764	response to oxidative stress
NIY03_RS15440	COG0037	tRNA processing
NIY03_RS15450	COG0248	Ppx GppA phosphatase
NIY03_RS15480	COG0072	phenylalanine-tRNA ligase activity
NIY03_RS15525	COG1238	metal cluster binding
NIY03_RS15530	COG0625	glutathione transferase activity
NIY03_RS15545	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS15550	COG3028	Belongs to the UPF0307 family
NIY03_RS15555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY03_RS15575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIY03_RS15580	COG0617	tRNA 3'-terminal CCA addition
NIY03_RS15585	COG1555	photosystem II stabilization
NIY03_RS15590	COG3956	TIGRFAM MazG family protein
NIY03_RS15600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY03_RS15620	COG0784	Response regulator, receiver
NIY03_RS15620	COG2205	protein histidine kinase activity
NIY03_RS15620	COG5002	protein histidine kinase activity
NIY03_RS15625	COG1024	Enoyl-CoA hydratase
NIY03_RS15630	COG2084	Dehydrogenase
NIY03_RS15635	COG3622	Belongs to the hyi family
NIY03_RS15665	COG0697	spore germination
NIY03_RS15675	COG2814	Major facilitator Superfamily
NIY03_RS15680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY03_RS15690	COG0583	DNA-binding transcription factor activity
NIY03_RS15700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NIY03_RS15710	COG0084	hydrolase, TatD family'
NIY03_RS15725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIY03_RS15775	COG0440	acetolactate synthase activity
NIY03_RS15780	COG0028	Belongs to the TPP enzyme family
NIY03_RS15805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY03_RS15810	COG1136	(ABC) transporter
NIY03_RS15810	COG0577	efflux transmembrane transporter activity
NIY03_RS15815	COG1538	Outer membrane efflux protein
NIY03_RS15830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIY03_RS15835	COG1162	GTPase activity
NIY03_RS15845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NIY03_RS15865	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NIY03_RS15870	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS15910	COG2986	histidine ammonia-lyase
NIY03_RS15920	COG1216	Glycosyl transferase, family 2
NIY03_RS15925	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS15935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY03_RS15980	COG1426	Protein conserved in bacteria
NIY03_RS16015	COG0793	Belongs to the peptidase S41A family
NIY03_RS16030	COG2267	carboxylic ester hydrolase activity
NIY03_RS16040	COG1012	belongs to the aldehyde dehydrogenase family
NIY03_RS16045	COG3265	gluconokinase activity
NIY03_RS16055	COG0800	Aldolase
NIY03_RS16065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIY03_RS16070	COG0280	phosphate acetyltransferase
NIY03_RS16070	COG0857	belongs to the CobB CobQ family
NIY03_RS16075	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY03_RS16075	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY03_RS16095	COG0740	serine-type endopeptidase activity
NIY03_RS16105	COG4774	siderophore transport
NIY03_RS16115	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIY03_RS16125	COG2813	Specifically methylates the guanine in position
NIY03_RS16125	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY03_RS16225	COG0788	formyltetrahydrofolate deformylase activity
NIY03_RS16250	COG4651	solute:proton antiporter activity
NIY03_RS16250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY03_RS16270	COG0724	RNA recognition motif
NIY03_RS16275	COG0210	DNA helicase
NIY03_RS16300	COG1733	regulation of RNA biosynthetic process
NIY03_RS16310	COG2900	Belongs to the SlyX family
NIY03_RS16315	COG0488	(ABC) transporter
NIY03_RS16320	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS16325	COG1560	Kdo2-lipid A biosynthetic process
NIY03_RS16335	COG1301	dicarboxylic acid transport
NIY03_RS16390	COG0473	3-isopropylmalate dehydrogenase activity
NIY03_RS16445	COG0583	DNA-binding transcription factor activity
NIY03_RS16455	COG0625	glutathione transferase activity
NIY03_RS16460	COG2378	regulation of single-species biofilm formation
NIY03_RS16465	COG0546	phosphoglycolate phosphatase activity
NIY03_RS16475	COG1530	ribonuclease E activity
NIY03_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS16495	COG0583	DNA-binding transcription factor activity
NIY03_RS16500	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS16505	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NIY03_RS16515	COG0534	Mate efflux family protein
NIY03_RS16530	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NIY03_RS16555	COG0493	'glutamate synthase
NIY03_RS16555	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY03_RS16565	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NIY03_RS16570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY03_RS16585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY03_RS16595	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NIY03_RS16595	COG0644	oxidoreductase
NIY03_RS16605	COG0425	Belongs to the sulfur carrier protein TusA family
NIY03_RS16610	COG4535	Mg2 and Co2 transporter CorC
NIY03_RS16620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY03_RS16640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIY03_RS16645	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY03_RS16645	COG0475	glutathione-regulated potassium exporter activity
NIY03_RS16660	COG0484	heat shock protein binding
NIY03_RS16665	COG0789	Transcriptional regulator
NIY03_RS16670	COG0598	Magnesium transport protein CorA
NIY03_RS16685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY03_RS16690	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY03_RS16695	COG1074	ATP-dependent DNA helicase activity
NIY03_RS16700	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NIY03_RS16720	COG2226	methyltransferase
NIY03_RS16740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIY03_RS16755	COG2111	Na H antiporter
NIY03_RS16755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY03_RS16760	COG1006	Multisubunit Na H antiporter MnhC subunit
NIY03_RS16765	COG0651	ATP synthesis coupled electron transport
NIY03_RS16770	COG1863	multisubunit Na H antiporter MnhE subunit
NIY03_RS16775	COG2212	antiporter activity
NIY03_RS16780	COG1320	monovalent cation:proton antiporter activity
NIY03_RS16795	COG0195	Participates in both transcription termination and antitermination
NIY03_RS16845	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NIY03_RS16850	COG0237	dephospho-CoA kinase activity
NIY03_RS16860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY03_RS16875	COG0497	DNA recombination
NIY03_RS16885	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIY03_RS16915	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY03_RS16915	COG2169	Transcriptional regulator
NIY03_RS16920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIY03_RS16985	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NIY03_RS17000	COG0326	Molecular chaperone. Has ATPase activity
NIY03_RS17015	COG2056	Na+-H+ antiporter family
NIY03_RS17020	COG0596	Alpha beta hydrolase
NIY03_RS17115	COG0546	phosphoglycolate phosphatase activity
NIY03_RS17120	COG1716	ATPase activity
NIY03_RS17175	COG0181	hydroxymethylbilane synthase activity
NIY03_RS17185	COG3275	phosphorelay sensor kinase activity
NIY03_RS17205	COG1538	Outer membrane efflux protein
NIY03_RS17210	COG0697	spore germination
NIY03_RS17235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY03_RS17240	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NIY03_RS17245	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY03_RS17250	COG0772	Belongs to the SEDS family
NIY03_RS17275	COG4974	Belongs to the 'phage' integrase family
NIY03_RS17280	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY03_RS17290	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIY03_RS17300	COG2197	response regulator
NIY03_RS17315	COG0793	Belongs to the peptidase S41A family
NIY03_RS17320	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIY03_RS17325	COG0795	lipopolysaccharide-transporting ATPase activity
NIY03_RS17365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY03_RS17365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY03_RS17375	COG0004	ammonium transporteR
NIY03_RS17380	COG0347	Belongs to the P(II) protein family
NIY03_RS17400	COG0659	secondary active sulfate transmembrane transporter activity
NIY03_RS17405	COG0589	response to stress
NIY03_RS17470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY03_RS17490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIY03_RS17505	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS17515	COG0477	Major facilitator Superfamily
NIY03_RS17520	COG2860	membrane
NIY03_RS17525	COG3012	SEC-C Motif Domain Protein
NIY03_RS17530	COG1253	flavin adenine dinucleotide binding
NIY03_RS17540	COG0477	Major facilitator Superfamily
NIY03_RS17550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY03_RS17590	COG0655	NAD(P)H dehydrogenase (quinone) activity
NIY03_RS17600	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NIY03_RS17670	COG0758	DNA mediated transformation
NIY03_RS17680	COG0697	spore germination
NIY03_RS17685	COG1309	transcriptional regulator
NIY03_RS17700	COG0386	Belongs to the glutathione peroxidase family
NIY03_RS17770	COG1121	(ABC) transporter
NIY03_RS17775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NIY03_RS17780	COG1280	lysine exporter protein (LysE YggA)
NIY03_RS17785	COG2837	iron assimilation
NIY03_RS17790	COG0281	malic enzyme
NIY03_RS17835	COG0519	Catalyzes the synthesis of GMP from XMP
NIY03_RS17835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY03_RS17840	COG4399	Belongs to the UPF0754 family
NIY03_RS17845	COG2259	Doxx family
NIY03_RS17850	COG0586	Pfam SNARE associated Golgi protein
NIY03_RS17865	COG1192	Involved in chromosome partitioning
NIY03_RS17875	COG0271	Belongs to the BolA IbaG family
NIY03_RS17915	COG3321	synthase
NIY03_RS17915	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NIY03_RS17915	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NIY03_RS17915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY03_RS17920	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS17925	COG0318	PFAM AMP-dependent synthetase and ligase
NIY03_RS17930	COG2197	response regulator
NIY03_RS17940	COG3916	Acyl-homoserine-lactone synthase
NIY03_RS17945	COG0477	Major facilitator Superfamily
NIY03_RS17950	COG1024	Enoyl-CoA hydratase
NIY03_RS17955	COG1024	Enoyl-CoA hydratase
NIY03_RS17960	COG1960	acyl-CoA dehydrogenase activity
NIY03_RS17965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY03_RS17985	COG1113	amino acid transport
NIY03_RS17990	COG1113	amino acid transport
NIY03_RS17995	COG0251	oxidation-reduction process
NIY03_RS18035	COG0564	pseudouridine synthase activity
NIY03_RS18115	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIY03_RS18130	COG1802	Transcriptional regulator
NIY03_RS18140	COG1448	Aminotransferase
NIY03_RS18145	COG0277	FAD linked oxidase domain protein
NIY03_RS18155	COG2186	Transcriptional regulator
NIY03_RS18165	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY03_RS18185	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NIY03_RS18190	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NIY03_RS18215	COG0438	transferase activity, transferring glycosyl groups
NIY03_RS18245	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NIY03_RS18275	COG0728	peptidoglycan biosynthetic process
NIY03_RS18280	COG3023	N-Acetylmuramoyl-L-alanine amidase
NIY03_RS18340	COG0546	phosphoglycolate phosphatase activity
NIY03_RS18345	COG1028	Short-chain dehydrogenase reductase Sdr
NIY03_RS18365	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY03_RS18370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY03_RS18375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY03_RS18380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY03_RS18385	COG1116	anion transmembrane transporter activity
NIY03_RS18390	COG1309	transcriptional regulator
NIY03_RS18395	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIY03_RS18405	COG0196	riboflavin kinase activity
NIY03_RS18410	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIY03_RS18420	COG1047	Peptidyl-prolyl cis-trans
NIY03_RS18460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIY03_RS18465	COG0657	acetylesterase activity
NIY03_RS18485	COG0583	DNA-binding transcription factor activity
NIY03_RS18515	COG2951	lytic endotransglycosylase activity
NIY03_RS18520	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIY03_RS18535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NIY03_RS18545	COG0671	phosphoesterase, PA-phosphatase related
NIY03_RS18550	COG0861	Integral membrane protein TerC family
NIY03_RS18560	COG0754	glutathionylspermidine amidase activity
NIY03_RS18570	COG0402	S-adenosylhomocysteine deaminase activity
NIY03_RS18585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY03_RS18590	COG1230	cation diffusion facilitator family transporter
NIY03_RS18605	COG0706	membrane insertase activity