locus-tag	class	description
H1I73_RS00010	COG0592	DNA-directed DNA polymerase activity
H1I73_RS00020	COG0187	DNA topoisomerase II activity
H1I73_RS00030	COG0586	Pfam SNARE associated Golgi protein
H1I73_RS00035	COG0488	(ABC) transporter
H1I73_RS00060	COG0596	Alpha beta hydrolase
H1I73_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I73_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I73_RS00110	COG0733	neurotransmitter:sodium symporter activity
H1I73_RS00150	COG2233	PERMEase
H1I73_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS00200	COG2814	Major facilitator Superfamily
H1I73_RS00205	COG0656	L-ascorbic acid biosynthetic process
H1I73_RS00210	COG0583	DNA-binding transcription factor activity
H1I73_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS00230	COG1064	alcohol dehydrogenase
H1I73_RS00235	COG2818	Glycosylase
H1I73_RS00250	COG1194	a g-specific adenine glycosylase
H1I73_RS00270	COG2983	Belongs to the UPF0260 family
H1I73_RS00275	COG2133	pyrroloquinoline quinone binding
H1I73_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I73_RS00285	COG2116	formate transmembrane transporter activity
H1I73_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS00310	COG1335	isochorismatase
H1I73_RS00315	COG0385	Bile acid
H1I73_RS00320	COG0534	Mate efflux family protein
H1I73_RS00325	COG1683	Conserved Protein
H1I73_RS00345	COG0625	glutathione transferase activity
H1I73_RS00355	COG1113	amino acid transport
H1I73_RS00365	COG0523	cobalamin synthesis protein
H1I73_RS00375	COG2188	Transcriptional regulator
H1I73_RS00405	COG0010	Belongs to the arginase family
H1I73_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I73_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I73_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I73_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I73_RS00540	COG0534	Mate efflux family protein
H1I73_RS00545	COG0436	Aminotransferase
H1I73_RS00550	COG2733	membrane
H1I73_RS00565	COG2918	glutathione biosynthetic process
H1I73_RS00580	COG1388	LysM domain
H1I73_RS00580	COG0791	NLP P60 protein
H1I73_RS00595	COG3150	esterase
H1I73_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I73_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS00630	COG2233	PERMEase
H1I73_RS00635	COG2351	hydroxyisourate hydrolase activity
H1I73_RS00670	COG3706	GGDEF domain
H1I73_RS00685	COG1393	Belongs to the ArsC family
H1I73_RS00690	COG0708	Exodeoxyribonuclease III
H1I73_RS00710	COG0189	ligase activity
H1I73_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I73_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I73_RS00755	COG4942	peptidase
H1I73_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I73_RS00775	COG2119	membrane
H1I73_RS00780	COG4774	siderophore transport
H1I73_RS00785	COG0426	domain, Protein
H1I73_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I73_RS00830	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS00835	COG1519	Transferase
H1I73_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I73_RS00845	COG0668	transmembrane transport
H1I73_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS00860	COG1335	isochorismatase
H1I73_RS00865	COG1522	sequence-specific DNA binding
H1I73_RS00870	COG3328	transposase activity
H1I73_RS00895	COG2198	Histidine kinase
H1I73_RS00895	COG0784	Response regulator, receiver
H1I73_RS00895	COG2205	protein histidine kinase activity
H1I73_RS00900	COG3162	membrane
H1I73_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I73_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I73_RS00940	COG1309	transcriptional regulator
H1I73_RS00960	COG0351	phosphomethylpyrimidine kinase
H1I73_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I73_RS00970	COG2814	Major facilitator Superfamily
H1I73_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I73_RS00995	COG1113	amino acid transport
H1I73_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS01020	COG1335	isochorismatase
H1I73_RS01050	COG2814	Major facilitator Superfamily
H1I73_RS01055	COG0583	DNA-binding transcription factor activity
H1I73_RS01075	COG0667	Aldo Keto reductase
H1I73_RS01110	COG1733	regulation of RNA biosynthetic process
H1I73_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I73_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
H1I73_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I73_RS01255	COG0427	acetyl-CoA hydrolase
H1I73_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS01285	COG4221	oxidoreductase activity
H1I73_RS01290	COG2873	o-acetylhomoserine
H1I73_RS01380	COG0833	amino acid
H1I73_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I73_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I73_RS01445	COG2226	methyltransferase
H1I73_RS01495	COG0067	glutamate synthase
H1I73_RS01495	COG0069	glutamate synthase activity
H1I73_RS01495	COG0070	glutamate synthase
H1I73_RS01500	COG0493	'glutamate synthase
H1I73_RS01510	COG1704	LemA family
H1I73_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I73_RS01535	COG3307	-O-antigen
H1I73_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I73_RS01570	COG0194	GDP metabolic process
H1I73_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I73_RS01640	COG5380	lipid catabolic process
H1I73_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I73_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I73_RS01675	COG0277	FAD linked oxidase domain protein
H1I73_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I73_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS01705	COG1289	transmembrane transporter activity
H1I73_RS01715	COG0628	permease
H1I73_RS01720	COG1192	Involved in chromosome partitioning
H1I73_RS01750	COG0833	amino acid
H1I73_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I73_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I73_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS01810	COG0583	DNA-binding transcription factor activity
H1I73_RS01855	COG0517	IMP dehydrogenase activity
H1I73_RS01860	COG1983	PspC domain protein
H1I73_RS01870	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS01885	COG0408	coproporphyrinogen oxidase activity
H1I73_RS01905	COG0513	Belongs to the DEAD box helicase family
H1I73_RS01915	COG1127	ABC transporter
H1I73_RS01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I73_RS01930	COG2854	intermembrane phospholipid transfer
H1I73_RS01940	COG0598	Magnesium transport protein CorA
H1I73_RS01950	COG0494	nUDIX hydrolase
H1I73_RS01955	COG1040	competence protein
H1I73_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I73_RS01980	COG1946	Acyl-CoA thioesterase
H1I73_RS01985	COG1301	dicarboxylic acid transport
H1I73_RS02000	COG1959	2 iron, 2 sulfur cluster binding
H1I73_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS02005	COG1017	nitric oxide dioxygenase activity
H1I73_RS02010	COG0433	COG0433 Predicted ATPase
H1I73_RS02015	COG0626	cystathionine gamma-synthase activity
H1I73_RS02170	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I73_RS02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I73_RS02210	COG0339	signal peptide processing
H1I73_RS02215	COG0557	exoribonuclease II activity
H1I73_RS02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I73_RS02265	COG2169	Transcriptional regulator
H1I73_RS02270	COG0697	spore germination
H1I73_RS02275	COG1295	ribonuclease BN
H1I73_RS02310	COG1702	phosphate starvation-inducible protein PhoH
H1I73_RS02320	COG0739	heme binding
H1I73_RS02320	COG1196	nuclear chromosome segregation
H1I73_RS02320	COG0741	lytic transglycosylase activity
H1I73_RS02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I73_RS02355	COG1183	phosphatidylcholine synthase activity
H1I73_RS02400	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02405	COG1309	transcriptional regulator
H1I73_RS02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I73_RS02425	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02445	COG2969	positive regulation of protein catabolic process
H1I73_RS02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I73_RS02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I73_RS02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I73_RS02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I73_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I73_RS02510	COG1408	metallophosphoesterase
H1I73_RS02520	COG2199	diguanylate cyclase activity
H1I73_RS02580	COG1607	acyl-coa hydrolase
H1I73_RS02610	COG2350	Protein conserved in bacteria
H1I73_RS02620	COG0613	PHP domain protein
H1I73_RS02625	COG3781	membrane
H1I73_RS02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I73_RS02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I73_RS02650	COG1862	Preprotein translocase
H1I73_RS02680	COG2205	protein histidine kinase activity
H1I73_RS02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I73_RS02705	COG0726	polysaccharide deacetylase
H1I73_RS02710	COG0463	Glycosyl transferase, family 2
H1I73_RS02715	COG0438	transferase activity, transferring glycosyl groups
H1I73_RS02780	COG0625	glutathione transferase activity
H1I73_RS02785	COG0583	DNA-binding transcription factor activity
H1I73_RS02790	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02795	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02805	COG2205	protein histidine kinase activity
H1I73_RS02810	COG0745	RESPONSE REGULATOR receiver
H1I73_RS02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I73_RS02835	COG2096	Adenosyltransferase
H1I73_RS02885	COG0285	dihydrofolate synthase activity
H1I73_RS02905	COG0450	alkyl hydroperoxide reductase
H1I73_RS02920	COG0477	Major facilitator Superfamily
H1I73_RS02925	COG1272	protein, Hemolysin III
H1I73_RS02955	COG0183	Belongs to the thiolase family
H1I73_RS02960	COG2207	Transcriptional regulator
H1I73_RS02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS03000	COG0183	Belongs to the thiolase family
H1I73_RS03010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I73_RS03010	COG2885	chlorophyll binding
H1I73_RS03020	COG1690	Belongs to the RtcB family
H1I73_RS03025	COG0833	amino acid
H1I73_RS03035	COG2233	PERMEase
H1I73_RS03040	COG1217	gtp-binding protein TYPA
H1I73_RS03065	COG2094	Belongs to the DNA glycosylase MPG family
H1I73_RS03070	COG4772	TonB-dependent receptor
H1I73_RS03085	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS03090	COG0679	Auxin Efflux Carrier
H1I73_RS03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS03105	COG0354	folic acid binding
H1I73_RS03115	COG3189	MarR family transcriptional regulator
H1I73_RS03120	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I73_RS03125	COG3422	double-strand break repair
H1I73_RS03165	COG0840	transmembrane signaling receptor activity
H1I73_RS03185	COG5510	response to toxic substance
H1I73_RS03195	COG2832	Protein of unknown function (DUF454)
H1I73_RS03200	COG1376	ErfK ybiS ycfS ynhG family protein
H1I73_RS03240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I73_RS03250	COG1289	transmembrane transporter activity
H1I73_RS03255	COG2814	Major facilitator Superfamily
H1I73_RS03275	COG1115	amino acid carrier protein
H1I73_RS03280	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I73_RS03285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I73_RS03290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I73_RS03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I73_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I73_RS03345	COG1077	Cell shape determining protein MreB Mrl
H1I73_RS03350	COG1792	Involved in formation and maintenance of cell shape
H1I73_RS03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I73_RS03360	COG0424	maF-like protein
H1I73_RS03365	COG1530	ribonuclease E activity
H1I73_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS03385	COG0560	Phosphoserine phosphatase
H1I73_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS03420	COG2207	Transcriptional regulator
H1I73_RS03440	COG1113	amino acid transport
H1I73_RS03445	COG2828	Protein conserved in bacteria
H1I73_RS03450	COG0142	geranyltranstransferase activity
H1I73_RS03455	COG2315	Protein conserved in bacteria
H1I73_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I73_RS03505	COG0745	RESPONSE REGULATOR receiver
H1I73_RS03510	COG0642	Histidine kinase
H1I73_RS03520	COG0004	ammonium transporteR
H1I73_RS03525	COG0583	DNA-binding transcription factor activity
H1I73_RS03545	COG0525	valine-tRNA ligase activity
H1I73_RS03555	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS03565	COG0393	Putative heavy-metal-binding
H1I73_RS03570	COG0393	Putative heavy-metal-binding
H1I73_RS03575	COG1538	Outer membrane efflux protein
H1I73_RS03585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS03590	COG0671	phosphoesterase, PA-phosphatase related
H1I73_RS03620	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I73_RS03635	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I73_RS03635	COG1648	precorrin-2 dehydrogenase activity
H1I73_RS03640	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I73_RS03645	COG1733	regulation of RNA biosynthetic process
H1I73_RS03655	COG0531	amino acid
H1I73_RS03670	COG0321	lipoyl(octanoyl) transferase activity
H1I73_RS03675	COG2921	Belongs to the UPF0250 family
H1I73_RS03715	COG2009	succinate dehydrogenase
H1I73_RS03720	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I73_RS03725	COG1053	succinate dehydrogenase
H1I73_RS03730	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I73_RS03755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS03775	COG2354	Protein conserved in bacteria
H1I73_RS03780	COG2321	neutral zinc metallopeptidase
H1I73_RS03835	COG2843	Capsule synthesis protein
H1I73_RS03850	COG0589	response to stress
H1I73_RS03895	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I73_RS03900	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I73_RS03950	COG0477	Major facilitator Superfamily
H1I73_RS03955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I73_RS03970	COG1597	lipid kinase activity
H1I73_RS03975	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I73_RS04005	COG0584	glycerophosphoryl diester phosphodiesterase
H1I73_RS04025	COG0741	lytic transglycosylase activity
H1I73_RS04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I73_RS04060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS04085	COG0778	Nitroreductase
H1I73_RS04100	COG1929	Belongs to the glycerate kinase type-1 family
H1I73_RS04105	COG0243	molybdopterin cofactor binding
H1I73_RS04110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I73_RS04115	COG3339	Conserved Protein
H1I73_RS04125	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I73_RS04140	COG1113	amino acid transport
H1I73_RS04150	COG0019	diaminopimelate decarboxylase activity
H1I73_RS04160	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS04165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I73_RS04195	COG0463	Glycosyl transferase, family 2
H1I73_RS04215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS04250	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I73_RS04255	COG1136	(ABC) transporter
H1I73_RS04260	COG0658	competence protein
H1I73_RS04260	COG2333	competence protein COMEC
H1I73_RS04270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I73_RS04270	COG0616	signal peptide processing
H1I73_RS04275	COG0596	Alpha beta hydrolase
H1I73_RS04280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I73_RS04290	COG0628	permease
H1I73_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I73_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
H1I73_RS04365	COG0824	Thioesterase
H1I73_RS04370	COG1473	amidohydrolase
H1I73_RS04390	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I73_RS04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I73_RS04395	COG2814	Major facilitator Superfamily
H1I73_RS04405	COG1024	Enoyl-CoA hydratase
H1I73_RS04410	COG1051	belongs to the nudix hydrolase family
H1I73_RS04410	COG1056	cytidyltransferase-related domain
H1I73_RS04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I73_RS04435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I73_RS04450	COG4625	pathogenesis
H1I73_RS04455	COG0583	DNA-binding transcription factor activity
H1I73_RS04460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I73_RS04465	COG4208	sulfate ABC transporter
H1I73_RS04470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I73_RS04480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I73_RS04485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS04490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I73_RS04525	COG0681	Belongs to the peptidase S26 family
H1I73_RS04540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I73_RS04550	COG1381	Involved in DNA repair and RecF pathway recombination
H1I73_RS04555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I73_RS04565	COG4221	oxidoreductase activity
H1I73_RS04595	COG0436	Aminotransferase
H1I73_RS04615	COG0556	nucleotide-excision repair
H1I73_RS04670	COG2070	2-Nitropropane dioxygenase
H1I73_RS04700	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS04715	COG0415	Belongs to the DNA photolyase family
H1I73_RS04725	COG1252	NADH dehydrogenase
H1I73_RS04730	COG1686	Belongs to the peptidase S11 family
H1I73_RS04745	COG1187	pseudouridine synthase activity
H1I73_RS04770	COG0477	Major facilitator Superfamily
H1I73_RS04775	COG0583	DNA-binding transcription factor activity
H1I73_RS04780	COG1823	symporter activity
H1I73_RS04790	COG0612	Peptidase, M16
H1I73_RS04815	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS04865	COG1309	transcriptional regulator
H1I73_RS04875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS04880	COG0076	glutamate decarboxylase activity
H1I73_RS04890	COG1522	sequence-specific DNA binding
H1I73_RS04895	COG3961	Belongs to the TPP enzyme family
H1I73_RS04900	COG1113	amino acid transport
H1I73_RS04905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I73_RS04910	COG0573	inorganic phosphate transmembrane transporter activity
H1I73_RS04920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I73_RS04925	COG0616	signal peptide processing
H1I73_RS04935	COG3328	transposase activity
H1I73_RS04965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I73_RS04970	COG1686	Belongs to the peptidase S11 family
H1I73_RS04995	COG0583	DNA-binding transcription factor activity
H1I73_RS05000	COG1067	ATP-dependent peptidase activity
H1I73_RS05045	COG1966	Carbon starvation protein
H1I73_RS05050	COG2879	small protein
H1I73_RS05080	COG2508	Transcriptional regulator
H1I73_RS05080	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I73_RS05100	COG1113	amino acid transport
H1I73_RS05105	COG0583	DNA-binding transcription factor activity
H1I73_RS05110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS05125	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS05130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS05135	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I73_RS05135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS05170	COG2814	Major facilitator Superfamily
H1I73_RS05175	COG4948	Mandelate Racemase Muconate Lactonizing
H1I73_RS05185	COG1309	transcriptional regulator
H1I73_RS05205	COG1741	Belongs to the pirin family
H1I73_RS05215	COG2964	Protein conserved in bacteria
H1I73_RS05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS05235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I73_RS05240	COG4605	iron ion homeostasis
H1I73_RS05245	COG4604	ABC transporter, ATP-binding protein
H1I73_RS05250	COG4607	ABC-type enterochelin transport system periplasmic component
H1I73_RS05255	COG4774	siderophore transport
H1I73_RS05265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS05270	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I73_RS05275	COG3433	isochorismatase activity
H1I73_RS05275	COG1535	isochorismatase
H1I73_RS05290	COG1132	(ABC) transporter
H1I73_RS05295	COG1132	(ABC) transporter
H1I73_RS05300	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I73_RS05310	COG1169	isochorismate synthase
H1I73_RS05325	COG3739	integral membrane protein
H1I73_RS05350	COG0302	gtp cyclohydrolase
H1I73_RS05360	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I73_RS05390	COG0308	aminopeptidase N
H1I73_RS05395	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I73_RS05410	COG0174	glutamine synthetase
H1I73_RS05455	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I73_RS05460	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I73_RS05465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I73_RS05485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I73_RS05490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I73_RS05495	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I73_RS05510	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS05515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I73_RS05520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS05530	COG2223	nitrite transmembrane transporter activity
H1I73_RS05540	COG0024	Methionine aminopeptidase
H1I73_RS05545	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I73_RS05560	COG2207	Transcriptional regulator
H1I73_RS05590	COG0772	Belongs to the SEDS family
H1I73_RS05605	COG0842	Transport permease protein
H1I73_RS05610	COG1131	(ABC) transporter
H1I73_RS05655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS05670	COG4215	(ABC) transporter
H1I73_RS05675	COG4160	amino acid transport
H1I73_RS05680	COG4598	ABC transporter
H1I73_RS05690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I73_RS05695	COG0826	peptidase U32
H1I73_RS05700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS05715	COG1720	tRNA m6t6A37 methyltransferase activity
H1I73_RS05725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I73_RS05740	COG0642	Histidine kinase
H1I73_RS05750	COG0494	nUDIX hydrolase
H1I73_RS05760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I73_RS05765	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I73_RS05770	COG3139	Protein of unknown function (DUF1315)
H1I73_RS05775	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I73_RS05780	COG1301	dicarboxylic acid transport
H1I73_RS05785	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS05790	COG2819	hydrolase of the alpha beta superfamily
H1I73_RS05800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I73_RS05810	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I73_RS05815	COG1234	tRNA 3'-trailer cleavage
H1I73_RS05845	COG2363	Small membrane protein
H1I73_RS05865	COG0513	Belongs to the DEAD box helicase family
H1I73_RS05875	COG0778	Nitroreductase
H1I73_RS05905	COG1286	toxin biosynthetic process
H1I73_RS05930	COG4783	chaperone-mediated protein folding
H1I73_RS05935	COG1610	YqeY-like protein
H1I73_RS06035	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I73_RS06060	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I73_RS06065	COG0786	glutamate:sodium symporter activity
H1I73_RS06075	COG2186	Transcriptional regulator
H1I73_RS06125	COG0477	Major facilitator Superfamily
H1I73_RS06160	COG2995	paraquat-inducible protein a
H1I73_RS06165	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I73_RS06165	COG3008	intermembrane lipid transfer
H1I73_RS06185	COG0482	sulfurtransferase activity
H1I73_RS06200	COG0488	(ABC) transporter
H1I73_RS06205	COG3173	Aminoglycoside phosphotransferase
H1I73_RS06215	COG2433	Pfam Transposase IS66
H1I73_RS06255	COG1301	dicarboxylic acid transport
H1I73_RS06265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS06270	COG2011	ABC-type metal ion transport system permease component
H1I73_RS06275	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I73_RS06280	COG1464	Belongs to the NlpA lipoprotein family
H1I73_RS06285	COG0151	Belongs to the GarS family
H1I73_RS06290	COG0138	bifunctional purine biosynthesis protein purh
H1I73_RS06295	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I73_RS06325	COG2308	Evidence 4 Homologs of previously reported genes of
H1I73_RS06335	COG1305	Transglutaminase-like
H1I73_RS06345	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I73_RS06350	COG0305	Participates in initiation and elongation during chromosome replication
H1I73_RS06375	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I73_RS06385	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I73_RS06390	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I73_RS06415	COG0726	polysaccharide deacetylase
H1I73_RS06415	COG1649	PFAM Uncharacterised BCR, COG1649
H1I73_RS06420	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS06425	COG3658	cytochrome
H1I73_RS06435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS06450	COG0583	DNA-binding transcription factor activity
H1I73_RS06470	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS06475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS06490	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS06495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS06500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS06525	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I73_RS06530	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I73_RS06540	COG2205	protein histidine kinase activity
H1I73_RS06545	COG0745	RESPONSE REGULATOR receiver
H1I73_RS06570	COG0729	surface antigen
H1I73_RS06595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I73_RS06600	COG2814	Major facilitator Superfamily
H1I73_RS06615	COG0583	DNA-binding transcription factor activity
H1I73_RS06630	COG1187	pseudouridine synthase activity
H1I73_RS06650	COG0802	atpase or kinase
H1I73_RS06655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I73_RS06665	COG1923	regulation of RNA biosynthetic process
H1I73_RS06670	COG0697	spore germination
H1I73_RS06685	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I73_RS06695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I73_RS06700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I73_RS06700	COG0519	Catalyzes the synthesis of GMP from XMP
H1I73_RS06705	COG4302	ethanolamine ammonia-lyase activity
H1I73_RS06710	COG4303	Ethanolamine ammonia lyase large subunit
H1I73_RS06715	COG0531	amino acid
H1I73_RS06735	COG1454	alcohol dehydrogenase
H1I73_RS06740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I73_RS06750	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I73_RS06770	COG0308	aminopeptidase N
H1I73_RS06800	COG1605	Chorismate mutase
H1I73_RS06815	COG1309	transcriptional regulator
H1I73_RS06825	COG0668	transmembrane transport
H1I73_RS06860	COG4773	Receptor
H1I73_RS06880	COG0488	(ABC) transporter
H1I73_RS06885	COG0589	response to stress
H1I73_RS06930	COG3135	benzoate transporter
H1I73_RS06935	COG1522	sequence-specific DNA binding
H1I73_RS06945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I73_RS06950	COG0583	DNA-binding transcription factor activity
H1I73_RS06960	COG0183	Belongs to the thiolase family
H1I73_RS06970	COG2030	dehydratase
H1I73_RS06975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I73_RS06990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I73_RS07000	COG0824	Thioesterase
H1I73_RS07005	COG1454	alcohol dehydrogenase
H1I73_RS07015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I73_RS07035	COG0069	glutamate synthase activity
H1I73_RS07200	COG5410	chromosome segregation
H1I73_RS07385	COG2814	Major facilitator Superfamily
H1I73_RS07400	COG0511	ligase activity, forming carbon-carbon bonds
H1I73_RS07420	COG1116	anion transmembrane transporter activity
H1I73_RS07420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS07425	COG0745	RESPONSE REGULATOR receiver
H1I73_RS07435	COG2146	nitrite reductase [NAD(P)H] activity
H1I73_RS07435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS07440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS07445	COG0243	molybdopterin cofactor binding
H1I73_RS07455	COG0243	molybdopterin cofactor binding
H1I73_RS07460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I73_RS07475	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I73_RS07475	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I73_RS07480	COG0303	'Molybdopterin
H1I73_RS07490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS07495	COG0697	spore germination
H1I73_RS07515	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I73_RS07520	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I73_RS07575	COG2204	response regulator
H1I73_RS07580	COG3852	Histidine kinase
H1I73_RS07600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I73_RS07605	COG0575	Belongs to the CDS family
H1I73_RS07660	COG2137	regulation of response to DNA damage stimulus
H1I73_RS07670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I73_RS07675	COG1011	Hydrolase
H1I73_RS07700	COG1522	sequence-specific DNA binding
H1I73_RS07710	COG1113	amino acid transport
H1I73_RS07725	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS07730	COG2135	peptidase activity
H1I73_RS07745	COG3300	MHYT domain
H1I73_RS07745	COG5001	Diguanylate cyclase
H1I73_RS07765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I73_RS07765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I73_RS07765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I73_RS07770	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I73_RS07775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I73_RS07775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I73_RS07805	COG0024	Methionine aminopeptidase
H1I73_RS07810	COG0583	DNA-binding transcription factor activity
H1I73_RS07820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I73_RS07825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I73_RS07830	COG0517	IMP dehydrogenase activity
H1I73_RS07830	COG0516	GMP reductase activity
H1I73_RS07865	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I73_RS07880	COG4890	Cyd operon protein YbgT
H1I73_RS07885	COG1294	oxidase, subunit
H1I73_RS07900	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I73_RS07910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I73_RS07915	COG4774	siderophore transport
H1I73_RS07930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I73_RS07935	COG0569	domain protein
H1I73_RS07940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I73_RS07970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I73_RS07975	COG0542	response to heat
H1I73_RS08000	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS08000	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS08045	COG2323	membrane
H1I73_RS08050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I73_RS08060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS08065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS08070	COG0183	Belongs to the thiolase family
H1I73_RS08075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I73_RS08080	COG0596	Alpha beta hydrolase
H1I73_RS08085	COG2271	Major facilitator Superfamily
H1I73_RS08090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I73_RS08095	COG3485	protocatechuate 3,4-dioxygenase
H1I73_RS08105	COG0710	3-dehydroquinate dehydratase activity
H1I73_RS08110	COG3420	alginic acid biosynthetic process
H1I73_RS08115	COG3659	wide pore channel activity
H1I73_RS08120	COG4993	Dehydrogenase
H1I73_RS08130	COG2391	methyltransferase activity
H1I73_RS08145	COG1414	Transcriptional regulator
H1I73_RS08150	COG0583	DNA-binding transcription factor activity
H1I73_RS08155	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS08180	COG2814	Major facilitator Superfamily
H1I73_RS08190	COG0154	amidase activity
H1I73_RS08210	COG4638	Rieske (2fe-2S)
H1I73_RS08220	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS08230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS08240	COG3733	amine oxidase
H1I73_RS08250	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS08265	COG0183	Belongs to the thiolase family
H1I73_RS08270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS08275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS08285	COG4829	muconolactone delta-isomerase
H1I73_RS08290	COG4948	Mandelate Racemase Muconate Lactonizing
H1I73_RS08295	COG0583	DNA-binding transcription factor activity
H1I73_RS08305	COG2186	Transcriptional regulator
H1I73_RS08345	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS08365	COG3162	membrane
H1I73_RS08380	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08395	COG0753	catalase activity
H1I73_RS08415	COG1846	Transcriptional regulator
H1I73_RS08420	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS08420	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS08430	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I73_RS08460	COG1309	transcriptional regulator
H1I73_RS08470	COG1335	isochorismatase
H1I73_RS08475	COG0583	DNA-binding transcription factor activity
H1I73_RS08485	COG0475	glutathione-regulated potassium exporter activity
H1I73_RS08485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS08495	COG1473	amidohydrolase
H1I73_RS08505	COG2831	hemolysin activation secretion protein
H1I73_RS08510	COG3210	domain, Protein
H1I73_RS08540	COG2188	Transcriptional regulator
H1I73_RS08555	COG0583	DNA-binding transcription factor activity
H1I73_RS08585	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I73_RS08605	COG1566	PFAM secretion protein HlyD family protein
H1I73_RS08620	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08625	COG0129	dihydroxy-acid dehydratase activity
H1I73_RS08635	COG0583	DNA-binding transcription factor activity
H1I73_RS08640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I73_RS08650	COG2084	Dehydrogenase
H1I73_RS08655	COG2207	Transcriptional regulator
H1I73_RS08670	COG1064	alcohol dehydrogenase
H1I73_RS08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I73_RS08685	COG1120	ATPase activity
H1I73_RS08705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I73_RS08820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I73_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS08885	COG2207	Transcriptional regulator
H1I73_RS08895	COG2205	protein histidine kinase activity
H1I73_RS08900	COG0745	RESPONSE REGULATOR receiver
H1I73_RS08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS08910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I73_RS08915	COG1538	Outer membrane efflux protein
H1I73_RS08925	COG2072	flavoprotein involved in K transport
H1I73_RS08945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS08965	COG3539	Fimbrial protein
H1I73_RS08995	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I73_RS09005	COG0753	catalase activity
H1I73_RS09020	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I73_RS09085	COG3433	isochorismatase activity
H1I73_RS09085	COG1535	isochorismatase
H1I73_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I73_RS09100	COG4149	molybdate abc transporter
H1I73_RS09105	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I73_RS09115	COG4638	Rieske (2fe-2S)
H1I73_RS09120	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I73_RS09125	COG0543	2 iron, 2 sulfur cluster binding
H1I73_RS09125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09165	COG2207	Transcriptional regulator
H1I73_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09180	COG2610	gluconate transmembrane transporter activity
H1I73_RS09190	COG0583	DNA-binding transcription factor activity
H1I73_RS09200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS09205	COG2031	fatty acid transporter
H1I73_RS09210	COG0183	Belongs to the thiolase family
H1I73_RS09215	COG0583	DNA-binding transcription factor activity
H1I73_RS09220	COG0583	DNA-binding transcription factor activity
H1I73_RS09235	COG1027	Aspartate ammonia-lyase
H1I73_RS09245	COG0477	Major facilitator Superfamily
H1I73_RS09265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS09270	COG4521	taurine ABC transporter
H1I73_RS09285	COG2188	Transcriptional regulator
H1I73_RS09295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I73_RS09300	COG1733	regulation of RNA biosynthetic process
H1I73_RS09305	COG3708	Transcriptional regulator
H1I73_RS09305	COG2207	Transcriptional regulator
H1I73_RS09320	COG0730	response to heat
H1I73_RS09330	COG3453	Protein conserved in bacteria
H1I73_RS09330	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS09340	COG3781	membrane
H1I73_RS09345	COG1063	alcohol dehydrogenase
H1I73_RS09355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS09360	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I73_RS09365	COG0022	dehydrogenase e1 component
H1I73_RS09370	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I73_RS09375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I73_RS09390	COG3706	GGDEF domain
H1I73_RS09405	COG0133	tryptophan synthase activity
H1I73_RS09415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I73_RS09450	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I73_RS09475	COG2226	methyltransferase
H1I73_RS09530	COG0842	Transport permease protein
H1I73_RS09535	COG0842	Transport permease protein
H1I73_RS09540	COG1131	(ABC) transporter
H1I73_RS09555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I73_RS09560	COG4773	Receptor
H1I73_RS09580	COG0730	response to heat
H1I73_RS09585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I73_RS09605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I73_RS09620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I73_RS09660	COG4264	IucA IucC family
H1I73_RS09665	COG4264	IucA IucC family
H1I73_RS09685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I73_RS09700	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS09705	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS09710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I73_RS09715	COG2207	Transcriptional regulator
H1I73_RS09720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I73_RS09725	COG0776	regulation of translation
H1I73_RS09750	COG0822	iron-sulfur transferase activity
H1I73_RS09755	COG0316	Belongs to the HesB IscA family
H1I73_RS09785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I73_RS09805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I73_RS09810	COG0702	epimerase
H1I73_RS09845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I73_RS09855	COG0339	signal peptide processing
H1I73_RS09905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I73_RS09910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I73_RS09940	COG0776	regulation of translation
H1I73_RS10005	COG0084	hydrolase, TatD family'
H1I73_RS10025	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I73_RS10030	COG1132	(ABC) transporter
H1I73_RS10040	COG0811	peptide transport
H1I73_RS10045	COG1475	DNA binding
H1I73_RS10050	COG1192	Involved in chromosome partitioning
H1I73_RS10060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I73_RS10075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I73_RS10080	COG0191	fructose-bisphosphate aldolase activity
H1I73_RS10100	COG0424	maF-like protein
H1I73_RS10105	COG2850	peptidyl-arginine hydroxylation
H1I73_RS10115	COG0640	Transcriptional regulator
H1I73_RS10130	COG3619	membrane
H1I73_RS10140	COG1132	(ABC) transporter
H1I73_RS10160	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I73_RS10165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I73_RS10175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I73_RS10175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I73_RS10175	COG0506	proline dehydrogenase activity
H1I73_RS10180	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I73_RS10195	COG3698	Phosphodiester glycosidase
H1I73_RS10205	COG2353	YceI-like domain
H1I73_RS10215	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I73_RS10260	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I73_RS10260	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I73_RS10285	COG3539	Fimbrial protein
H1I73_RS10290	COG3121	Chaperone
H1I73_RS10315	COG0697	spore germination
H1I73_RS10325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I73_RS10335	COG0583	DNA-binding transcription factor activity
H1I73_RS10355	COG1309	transcriptional regulator
H1I73_RS10370	COG1522	sequence-specific DNA binding
H1I73_RS10380	COG1126	abc transporter atp-binding protein
H1I73_RS10385	COG0765	amino acid transport
H1I73_RS10390	COG0765	amino acid transport
H1I73_RS10420	COG1464	Belongs to the NlpA lipoprotein family
H1I73_RS10430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I73_RS10435	COG2011	ABC-type metal ion transport system permease component
H1I73_RS10440	COG0012	GTP binding
H1I73_RS10465	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I73_RS10505	COG0386	Belongs to the glutathione peroxidase family
H1I73_RS10515	COG0436	Aminotransferase
H1I73_RS10570	COG0583	DNA-binding transcription factor activity
H1I73_RS10575	COG0798	PFAM Bile acid sodium symporter
H1I73_RS10580	COG0640	Transcriptional regulator
H1I73_RS10595	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I73_RS10605	COG0583	DNA-binding transcription factor activity
H1I73_RS10615	COG1953	Uracil, thiamine, allantoin
H1I73_RS10625	COG2175	clavaminate synthase activity
H1I73_RS10630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS10635	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I73_RS10640	COG4521	taurine ABC transporter
H1I73_RS10650	COG0477	Major facilitator Superfamily
H1I73_RS10670	COG1271	oxidase subunit
H1I73_RS10675	COG1294	oxidase, subunit
H1I73_RS10685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS10705	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I73_RS10725	COG3052	prosthetic group binding
H1I73_RS10730	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I73_RS10740	COG2814	Major facilitator Superfamily
H1I73_RS10760	COG1346	cytolysis
H1I73_RS10770	COG0583	DNA-binding transcription factor activity
H1I73_RS10775	COG0625	glutathione transferase activity
H1I73_RS10780	COG0625	glutathione transferase activity
H1I73_RS10785	COG0583	DNA-binding transcription factor activity
H1I73_RS10800	COG1045	serine acetyltransferase
H1I73_RS10805	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I73_RS10810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I73_RS10820	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS10835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS10845	COG1126	abc transporter atp-binding protein
H1I73_RS10850	COG0765	amino acid transport
H1I73_RS10855	COG0765	amino acid transport
H1I73_RS10895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I73_RS10915	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS10965	COG0583	DNA-binding transcription factor activity
H1I73_RS10990	COG1309	transcriptional regulator
H1I73_RS10995	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11000	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I73_RS11005	COG1024	Enoyl-CoA hydratase
H1I73_RS11010	COG4770	biotin carboxylase activity
H1I73_RS11020	COG0583	DNA-binding transcription factor activity
H1I73_RS11035	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11045	COG2814	Major facilitator Superfamily
H1I73_RS11055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS11060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS11065	COG2814	Major facilitator Superfamily
H1I73_RS11070	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11075	COG1024	Enoyl-CoA hydratase
H1I73_RS11080	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS11085	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11090	COG0183	Belongs to the thiolase family
H1I73_RS11100	COG2814	Major facilitator Superfamily
H1I73_RS11110	COG1024	Enoyl-CoA hydratase
H1I73_RS11125	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11130	COG2814	Major facilitator Superfamily
H1I73_RS11135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I73_RS11140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I73_RS11155	COG3842	ATPase activity
H1I73_RS11160	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I73_RS11170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS11175	COG1414	Transcriptional regulator
H1I73_RS11185	COG0583	DNA-binding transcription factor activity
H1I73_RS11190	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I73_RS11195	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11205	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I73_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS11225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS11230	COG2267	carboxylic ester hydrolase activity
H1I73_RS11250	COG3038	cytochrome b561
H1I73_RS11255	COG0753	catalase activity
H1I73_RS11285	COG2050	protein possibly involved in aromatic compounds catabolism
H1I73_RS11295	COG3327	negative regulation of DNA-templated transcription, initiation
H1I73_RS11300	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I73_RS11305	COG0183	Belongs to the thiolase family
H1I73_RS11310	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11315	COG1024	Enoyl-CoA hydratase
H1I73_RS11320	COG1024	Enoyl-CoA hydratase
H1I73_RS11325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS11335	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I73_RS11340	COG3396	Phenylacetate-CoA oxygenase
H1I73_RS11345	COG3460	Phenylacetate-CoA oxygenase
H1I73_RS11350	COG3396	Phenylacetate-CoA oxygenase
H1I73_RS11355	COG2030	dehydratase
H1I73_RS11355	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11360	COG1760	l-serine dehydratase
H1I73_RS11365	COG0531	amino acid
H1I73_RS11370	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11385	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS11395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS11415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS11425	COG0789	Transcriptional regulator
H1I73_RS11440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I73_RS11455	COG2807	transmembrane transport
H1I73_RS11460	COG0590	tRNA wobble adenosine to inosine editing
H1I73_RS11575	COG1116	anion transmembrane transporter activity
H1I73_RS11580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS11590	COG0864	Transcriptional regulator
H1I73_RS11610	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS11615	COG0439	Biotin carboxylase
H1I73_RS11630	COG1063	alcohol dehydrogenase
H1I73_RS11640	COG1309	transcriptional regulator
H1I73_RS11660	COG0038	chloride channel
H1I73_RS11685	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I73_RS11690	COG0583	DNA-binding transcription factor activity
H1I73_RS11740	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11760	COG2814	Major facilitator Superfamily
H1I73_RS11770	COG1560	Kdo2-lipid A biosynthetic process
H1I73_RS11780	COG5006	permease, DMT superfamily
H1I73_RS11785	COG1522	sequence-specific DNA binding
H1I73_RS11800	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I73_RS11810	COG4122	O-methyltransferase activity
H1I73_RS11840	COG1538	Outer membrane efflux protein
H1I73_RS11845	COG1137	ATPase activity
H1I73_RS11850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I73_RS11860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I73_RS11865	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I73_RS11865	COG0517	IMP dehydrogenase activity
H1I73_RS11900	COG2814	Major facilitator Superfamily
H1I73_RS11935	COG1278	Cold shock
H1I73_RS11940	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS11970	COG1570	exodeoxyribonuclease VII activity
H1I73_RS12020	COG0583	DNA-binding transcription factor activity
H1I73_RS12025	COG4638	Rieske (2fe-2S)
H1I73_RS12030	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I73_RS12035	COG0543	2 iron, 2 sulfur cluster binding
H1I73_RS12035	COG0633	Ferredoxin
H1I73_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS12045	COG3135	benzoate transporter
H1I73_RS12050	COG2814	Major facilitator Superfamily
H1I73_RS12065	COG1643	Atp-dependent helicase
H1I73_RS12070	COG0450	alkyl hydroperoxide reductase
H1I73_RS12080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I73_RS12110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I73_RS12115	COG0625	glutathione transferase activity
H1I73_RS12125	COG2885	chlorophyll binding
H1I73_RS12160	COG0542	response to heat
H1I73_RS12175	COG1765	OsmC-like protein
H1I73_RS12195	COG0667	Aldo Keto reductase
H1I73_RS12210	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I73_RS12220	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I73_RS12230	COG0527	aspartate kinase activity
H1I73_RS12240	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I73_RS12250	COG3038	cytochrome b561
H1I73_RS12255	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I73_RS12260	COG2252	PERMEase
H1I73_RS12270	COG2072	flavoprotein involved in K transport
H1I73_RS12285	COG1741	Belongs to the pirin family
H1I73_RS12290	COG1309	transcriptional regulator
H1I73_RS12310	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS12310	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS12320	COG4251	negative regulation of phosphorylation
H1I73_RS12320	COG5001	Diguanylate cyclase
H1I73_RS12320	COG3706	GGDEF domain
H1I73_RS12320	COG2203	Gaf domain
H1I73_RS12330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS12350	COG4172	Belongs to the ABC transporter superfamily
H1I73_RS12355	COG4239	(ABC) transporter, permease
H1I73_RS12360	COG4174	ABC transporter (Permease)
H1I73_RS12370	COG0741	lytic transglycosylase activity
H1I73_RS12370	COG0741	lytic transglycosylase activity
H1I73_RS12370	COG1388	LysM domain
H1I73_RS12370	COG1388	LysM domain
H1I73_RS12375	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS12415	COG0583	DNA-binding transcription factor activity
H1I73_RS12420	COG1279	arginine transmembrane transporter activity
H1I73_RS12440	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS12445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS12450	COG0006	proline dipeptidase activity
H1I73_RS12490	COG2194	sulfuric ester hydrolase activity
H1I73_RS12870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I73_RS12895	COG3384	dioxygenase
H1I73_RS12905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I73_RS12910	COG2878	Part of a membrane complex involved in electron transport
H1I73_RS12915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I73_RS12940	COG0768	penicillin binding
H1I73_RS12945	COG0742	ribosomal rna small subunit methyltransferase
H1I73_RS12960	COG0830	nickel cation binding
H1I73_RS13005	COG1253	flavin adenine dinucleotide binding
H1I73_RS13010	COG2851	Citrate transporter
H1I73_RS13065	COG1773	rubredoxin
H1I73_RS13070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS13080	COG0583	DNA-binding transcription factor activity
H1I73_RS13105	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I73_RS13110	COG4181	ATPase activity
H1I73_RS13155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I73_RS13175	COG0306	phosphate transporter
H1I73_RS13185	COG3958	Transketolase
H1I73_RS13190	COG3959	Transketolase, thiamine diphosphate binding domain
H1I73_RS13195	COG2271	Major facilitator Superfamily
H1I73_RS13200	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13205	COG0583	DNA-binding transcription factor activity
H1I73_RS13220	COG2223	nitrite transmembrane transporter activity
H1I73_RS13225	COG2207	Transcriptional regulator
H1I73_RS13230	COG2066	Belongs to the glutaminase family
H1I73_RS13235	COG0242	peptide deformylase activity
H1I73_RS13240	COG0477	Major facilitator Superfamily
H1I73_RS13250	COG0028	Belongs to the TPP enzyme family
H1I73_RS13265	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13270	COG2267	carboxylic ester hydrolase activity
H1I73_RS13280	COG2271	Major facilitator Superfamily
H1I73_RS13285	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS13295	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13315	COG1414	Transcriptional regulator
H1I73_RS13330	COG1024	Enoyl-CoA hydratase
H1I73_RS13340	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS13345	COG1649	PFAM Uncharacterised BCR, COG1649
H1I73_RS13345	COG0726	polysaccharide deacetylase
H1I73_RS13355	COG4681	YaeQ
H1I73_RS13365	COG0523	cobalamin synthesis protein
H1I73_RS13375	COG1607	acyl-coa hydrolase
H1I73_RS13385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS13390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS13395	COG1309	transcriptional regulator
H1I73_RS13420	COG2040	homocysteine
H1I73_RS13425	COG0531	amino acid
H1I73_RS13480	COG1595	DNA-templated transcription, initiation
H1I73_RS13490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS13495	COG0477	Major facilitator Superfamily
H1I73_RS13515	COG0084	hydrolase, TatD family'
H1I73_RS13550	COG0629	single-stranded DNA binding
H1I73_RS13605	COG0582	viral genome integration into host DNA
H1I73_RS13705	COG0592	DNA-directed DNA polymerase activity
H1I73_RS13745	COG2026	Addiction module toxin, RelE StbE family
H1I73_RS13895	COG3755	Protein conserved in bacteria
H1I73_RS13940	COG1484	DNA-dependent DNA replication
H1I73_RS14030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS14100	COG0405	Gamma-glutamyltransferase
H1I73_RS14105	COG2814	Major facilitator Superfamily
H1I73_RS14115	COG2050	protein possibly involved in aromatic compounds catabolism
H1I73_RS14130	COG1090	epimerase
H1I73_RS14150	COG0420	3'-5' exonuclease activity
H1I73_RS14175	COG0735	belongs to the Fur family
H1I73_RS14180	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I73_RS14200	COG0121	glutamine amidotransferase
H1I73_RS14215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I73_RS14225	COG0210	DNA helicase
H1I73_RS14230	COG2885	chlorophyll binding
H1I73_RS14235	COG0204	Acyl-transferase
H1I73_RS14250	COG2894	cell division
H1I73_RS14270	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS14275	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I73_RS14275	COG1674	ftsk spoiiie
H1I73_RS14280	COG0492	ferredoxin-NADP+ reductase activity
H1I73_RS14285	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I73_RS14295	COG0456	acetyltransferase
H1I73_RS14340	COG1981	membrane
H1I73_RS14355	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I73_RS14355	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I73_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS14385	COG0657	acetylesterase activity
H1I73_RS14395	COG0473	3-isopropylmalate dehydrogenase activity
H1I73_RS14420	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I73_RS14445	COG0564	pseudouridine synthase activity
H1I73_RS14455	COG0358	DNA primase activity
H1I73_RS14470	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I73_RS14500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I73_RS14530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I73_RS14540	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS14540	COG0351	phosphomethylpyrimidine kinase
H1I73_RS14545	COG1652	LysM domain
H1I73_RS14570	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I73_RS14575	COG3101	peptidyl-lysine hydroxylation
H1I73_RS14580	COG0009	L-threonylcarbamoyladenylate synthase
H1I73_RS14585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I73_RS14590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I73_RS14605	COG4106	trans-aconitate 2-methyltransferase activity
H1I73_RS14620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS14620	COG2226	methyltransferase
H1I73_RS14620	COG0596	Alpha beta hydrolase
H1I73_RS14625	COG1877	trehalose-phosphatase activity
H1I73_RS14630	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I73_RS14635	COG2223	nitrite transmembrane transporter activity
H1I73_RS14655	COG1196	nuclear chromosome segregation
H1I73_RS14665	COG0730	response to heat
H1I73_RS14680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I73_RS14690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I73_RS14740	COG0489	protein tyrosine kinase activity
H1I73_RS14750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS14750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS14780	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I73_RS14785	COG2081	HI0933 family
H1I73_RS14795	COG0668	transmembrane transport
H1I73_RS14815	COG0583	DNA-binding transcription factor activity
H1I73_RS14835	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I73_RS14840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I73_RS14870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I73_RS14910	COG0745	RESPONSE REGULATOR receiver
H1I73_RS14930	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I73_RS14940	COG2205	protein histidine kinase activity
H1I73_RS15010	COG4993	Dehydrogenase
H1I73_RS15035	COG0384	phenazine biosynthesis protein PhzF
H1I73_RS15055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS15070	COG0583	DNA-binding transcription factor activity
H1I73_RS15100	COG0583	DNA-binding transcription factor activity
H1I73_RS15115	COG0583	DNA-binding transcription factor activity
H1I73_RS15120	COG1053	succinate dehydrogenase
H1I73_RS15130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I73_RS15135	COG2814	Major facilitator Superfamily
H1I73_RS15140	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS15145	COG0583	DNA-binding transcription factor activity
H1I73_RS15150	COG1063	alcohol dehydrogenase
H1I73_RS15180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I73_RS15185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I73_RS15190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I73_RS15205	COG3667	copper resistance
H1I73_RS15210	COG2132	Multicopper oxidase
H1I73_RS15220	COG0561	phosphatase activity
H1I73_RS15225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I73_RS15250	COG1214	PFAM Peptidase M22, glycoprotease
H1I73_RS15305	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I73_RS15315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I73_RS15320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I73_RS15325	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I73_RS15385	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I73_RS15395	COG1846	Transcriptional regulator
H1I73_RS15400	COG1764	response to oxidative stress
H1I73_RS15450	COG0037	tRNA processing
H1I73_RS15460	COG0248	Ppx GppA phosphatase
H1I73_RS15490	COG0072	phenylalanine-tRNA ligase activity
H1I73_RS15530	COG1238	metal cluster binding
H1I73_RS15535	COG0625	glutathione transferase activity
H1I73_RS15550	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS15555	COG3028	Belongs to the UPF0307 family
H1I73_RS15560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I73_RS15580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I73_RS15585	COG0617	tRNA 3'-terminal CCA addition
H1I73_RS15590	COG1555	photosystem II stabilization
H1I73_RS15595	COG3956	TIGRFAM MazG family protein
H1I73_RS15605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I73_RS15625	COG2205	protein histidine kinase activity
H1I73_RS15625	COG0784	Response regulator, receiver
H1I73_RS15625	COG5002	protein histidine kinase activity
H1I73_RS15630	COG1024	Enoyl-CoA hydratase
H1I73_RS15635	COG2084	Dehydrogenase
H1I73_RS15640	COG3622	Belongs to the hyi family
H1I73_RS15670	COG0697	spore germination
H1I73_RS15680	COG2814	Major facilitator Superfamily
H1I73_RS15685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I73_RS15695	COG0583	DNA-binding transcription factor activity
H1I73_RS15705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I73_RS15720	COG0084	hydrolase, TatD family'
H1I73_RS15735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I73_RS15765	COG0440	acetolactate synthase activity
H1I73_RS15770	COG0028	Belongs to the TPP enzyme family
H1I73_RS15795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS15800	COG0577	efflux transmembrane transporter activity
H1I73_RS15800	COG1136	(ABC) transporter
H1I73_RS15805	COG1538	Outer membrane efflux protein
H1I73_RS15820	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I73_RS15825	COG1162	GTPase activity
H1I73_RS15835	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I73_RS15855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I73_RS15860	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS15900	COG2986	histidine ammonia-lyase
H1I73_RS15915	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS15925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I73_RS15970	COG1426	Protein conserved in bacteria
H1I73_RS16005	COG0793	Belongs to the peptidase S41A family
H1I73_RS16020	COG2267	carboxylic ester hydrolase activity
H1I73_RS16030	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS16035	COG3265	gluconokinase activity
H1I73_RS16045	COG0800	Aldolase
H1I73_RS16060	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I73_RS16065	COG0280	phosphate acetyltransferase
H1I73_RS16065	COG0857	belongs to the CobB CobQ family
H1I73_RS16070	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I73_RS16070	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I73_RS16090	COG0740	serine-type endopeptidase activity
H1I73_RS16100	COG4774	siderophore transport
H1I73_RS16110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I73_RS16120	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS16120	COG2813	Specifically methylates the guanine in position
H1I73_RS16220	COG0788	formyltetrahydrofolate deformylase activity
H1I73_RS16245	COG4651	solute:proton antiporter activity
H1I73_RS16245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS16265	COG0724	RNA recognition motif
H1I73_RS16270	COG0210	DNA helicase
H1I73_RS16295	COG1733	regulation of RNA biosynthetic process
H1I73_RS16305	COG2900	Belongs to the SlyX family
H1I73_RS16310	COG0488	(ABC) transporter
H1I73_RS16315	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS16320	COG1560	Kdo2-lipid A biosynthetic process
H1I73_RS16330	COG1301	dicarboxylic acid transport
H1I73_RS16385	COG0473	3-isopropylmalate dehydrogenase activity
H1I73_RS16450	COG0583	DNA-binding transcription factor activity
H1I73_RS16460	COG0625	glutathione transferase activity
H1I73_RS16465	COG2378	regulation of single-species biofilm formation
H1I73_RS16470	COG0546	phosphoglycolate phosphatase activity
H1I73_RS16480	COG1530	ribonuclease E activity
H1I73_RS16485	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS16500	COG0583	DNA-binding transcription factor activity
H1I73_RS16505	COG4221	oxidoreductase activity
H1I73_RS16510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I73_RS16520	COG0534	Mate efflux family protein
H1I73_RS16535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I73_RS16575	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I73_RS16580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS16595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I73_RS16605	COG0644	oxidoreductase
H1I73_RS16605	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I73_RS16610	COG0425	Belongs to the sulfur carrier protein TusA family
H1I73_RS16615	COG4535	Mg2 and Co2 transporter CorC
H1I73_RS16625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS16645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I73_RS16650	COG0475	glutathione-regulated potassium exporter activity
H1I73_RS16650	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS16655	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I73_RS16665	COG0484	heat shock protein binding
H1I73_RS16670	COG0789	Transcriptional regulator
H1I73_RS16675	COG0598	Magnesium transport protein CorA
H1I73_RS16695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I73_RS16700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I73_RS16705	COG1074	ATP-dependent DNA helicase activity
H1I73_RS16710	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I73_RS16730	COG2226	methyltransferase
H1I73_RS16745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS16750	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I73_RS16765	COG2111	Na H antiporter
H1I73_RS16765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I73_RS16770	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I73_RS16775	COG0651	ATP synthesis coupled electron transport
H1I73_RS16780	COG1863	multisubunit Na H antiporter MnhE subunit
H1I73_RS16785	COG2212	antiporter activity
H1I73_RS16790	COG1320	monovalent cation:proton antiporter activity
H1I73_RS16805	COG0195	Participates in both transcription termination and antitermination
H1I73_RS16855	COG0237	dephospho-CoA kinase activity
H1I73_RS16865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I73_RS16880	COG0497	DNA recombination
H1I73_RS16890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I73_RS16920	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I73_RS16920	COG2169	Transcriptional regulator
H1I73_RS16925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I73_RS16990	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I73_RS17005	COG0326	Molecular chaperone. Has ATPase activity
H1I73_RS17020	COG2056	Na+-H+ antiporter family
H1I73_RS17025	COG0596	Alpha beta hydrolase
H1I73_RS17120	COG0546	phosphoglycolate phosphatase activity
H1I73_RS17125	COG1716	ATPase activity
H1I73_RS17170	COG0181	hydroxymethylbilane synthase activity
H1I73_RS17180	COG3275	phosphorelay sensor kinase activity
H1I73_RS17200	COG1538	Outer membrane efflux protein
H1I73_RS17205	COG0697	spore germination
H1I73_RS17230	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I73_RS17235	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I73_RS17240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I73_RS17245	COG0772	Belongs to the SEDS family
H1I73_RS17270	COG4974	Belongs to the 'phage' integrase family
H1I73_RS17275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS17285	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I73_RS17295	COG2197	response regulator
H1I73_RS17310	COG0793	Belongs to the peptidase S41A family
H1I73_RS17315	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I73_RS17320	COG0795	lipopolysaccharide-transporting ATPase activity
H1I73_RS17360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I73_RS17360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I73_RS17370	COG0004	ammonium transporteR
H1I73_RS17375	COG0347	Belongs to the P(II) protein family
H1I73_RS17385	COG0606	chelatase, subunit chli
H1I73_RS17465	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS17470	COG0589	response to stress
H1I73_RS17500	COG0606	chelatase, subunit chli
H1I73_RS17515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS17530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I73_RS17545	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS17555	COG0477	Major facilitator Superfamily
H1I73_RS17560	COG2860	membrane
H1I73_RS17570	COG1253	flavin adenine dinucleotide binding
H1I73_RS17590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I73_RS17625	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS17635	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I73_RS17670	COG1309	transcriptional regulator
H1I73_RS17705	COG0758	DNA mediated transformation
H1I73_RS17715	COG0697	spore germination
H1I73_RS17720	COG1309	transcriptional regulator
H1I73_RS17735	COG0386	Belongs to the glutathione peroxidase family
H1I73_RS17800	COG1121	(ABC) transporter
H1I73_RS17805	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I73_RS17810	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS17815	COG2837	iron assimilation
H1I73_RS17825	COG0281	malic enzyme
H1I73_RS17870	COG0519	Catalyzes the synthesis of GMP from XMP
H1I73_RS17870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I73_RS17875	COG4399	Belongs to the UPF0754 family
H1I73_RS17880	COG2259	Doxx family
H1I73_RS17900	COG1192	Involved in chromosome partitioning
H1I73_RS17910	COG0271	Belongs to the BolA IbaG family
H1I73_RS17930	COG2267	carboxylic ester hydrolase activity
H1I73_RS17950	COG3321	synthase
H1I73_RS17950	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I73_RS17950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I73_RS17950	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I73_RS17955	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS17965	COG2197	response regulator
H1I73_RS17975	COG3916	Acyl-homoserine-lactone synthase
H1I73_RS17980	COG0477	Major facilitator Superfamily
H1I73_RS17985	COG1024	Enoyl-CoA hydratase
H1I73_RS17990	COG1024	Enoyl-CoA hydratase
H1I73_RS17995	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS18000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS18020	COG1113	amino acid transport
H1I73_RS18025	COG1113	amino acid transport
H1I73_RS18030	COG0251	oxidation-reduction process
H1I73_RS18070	COG0564	pseudouridine synthase activity
H1I73_RS18130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I73_RS18145	COG1802	Transcriptional regulator
H1I73_RS18155	COG1448	Aminotransferase
H1I73_RS18160	COG0277	FAD linked oxidase domain protein
H1I73_RS18170	COG2186	Transcriptional regulator
H1I73_RS18180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I73_RS18185	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I73_RS18200	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I73_RS18205	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I73_RS18230	COG0438	transferase activity, transferring glycosyl groups
H1I73_RS18260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I73_RS18290	COG0728	peptidoglycan biosynthetic process
H1I73_RS18295	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I73_RS18350	COG0546	phosphoglycolate phosphatase activity
H1I73_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS18375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS18380	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS18385	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS18390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS18395	COG1116	anion transmembrane transporter activity
H1I73_RS18400	COG1309	transcriptional regulator
H1I73_RS18405	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I73_RS18415	COG0196	riboflavin kinase activity
H1I73_RS18420	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I73_RS18430	COG1047	Peptidyl-prolyl cis-trans
H1I73_RS18470	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I73_RS18475	COG0657	acetylesterase activity
H1I73_RS18525	COG2951	lytic endotransglycosylase activity
H1I73_RS18530	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I73_RS18545	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I73_RS18555	COG0671	phosphoesterase, PA-phosphatase related
H1I73_RS18560	COG0861	Integral membrane protein TerC family
H1I73_RS18570	COG0754	glutathionylspermidine amidase activity
H1I73_RS18580	COG0402	S-adenosylhomocysteine deaminase activity
H1I73_RS18595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS18600	COG1230	cation diffusion facilitator family transporter
H1I73_RS18615	COG0706	membrane insertase activity