locus-tag	class	description
H1I73_RS00010	COG0592	DNA-directed DNA polymerase activity
H1I73_RS00020	COG0187	DNA topoisomerase II activity
H1I73_RS00030	COG0586	Pfam SNARE associated Golgi protein
H1I73_RS00035	COG0488	(ABC) transporter
H1I73_RS00060	COG0596	Alpha beta hydrolase
H1I73_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I73_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I73_RS00110	COG0733	neurotransmitter:sodium symporter activity
H1I73_RS00150	COG2233	PERMEase
H1I73_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS00200	COG2814	Major facilitator Superfamily
H1I73_RS00205	COG0656	L-ascorbic acid biosynthetic process
H1I73_RS00210	COG0583	DNA-binding transcription factor activity
H1I73_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS00230	COG1064	alcohol dehydrogenase
H1I73_RS00235	COG2818	Glycosylase
H1I73_RS00250	COG1194	a g-specific adenine glycosylase
H1I73_RS00270	COG2983	Belongs to the UPF0260 family
H1I73_RS00275	COG2133	pyrroloquinoline quinone binding
H1I73_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I73_RS00285	COG2116	formate transmembrane transporter activity
H1I73_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS00310	COG1335	isochorismatase
H1I73_RS00315	COG0385	Bile acid
H1I73_RS00320	COG0534	Mate efflux family protein
H1I73_RS00325	COG1683	Conserved Protein
H1I73_RS00345	COG0625	glutathione transferase activity
H1I73_RS00355	COG1113	amino acid transport
H1I73_RS00365	COG0523	cobalamin synthesis protein
H1I73_RS00375	COG2188	Transcriptional regulator
H1I73_RS00405	COG0010	Belongs to the arginase family
H1I73_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I73_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I73_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I73_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I73_RS00540	COG0534	Mate efflux family protein
H1I73_RS00545	COG0436	Aminotransferase
H1I73_RS00550	COG2733	membrane
H1I73_RS00565	COG2918	glutathione biosynthetic process
H1I73_RS00580	COG1388	LysM domain
H1I73_RS00580	COG0791	NLP P60 protein
H1I73_RS00595	COG3150	esterase
H1I73_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I73_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS00630	COG2233	PERMEase
H1I73_RS00635	COG2351	hydroxyisourate hydrolase activity
H1I73_RS00670	COG3706	GGDEF domain
H1I73_RS00685	COG1393	Belongs to the ArsC family
H1I73_RS00690	COG0708	Exodeoxyribonuclease III
H1I73_RS00710	COG0189	ligase activity
H1I73_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I73_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I73_RS00755	COG4942	peptidase
H1I73_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I73_RS00775	COG2119	membrane
H1I73_RS00780	COG4774	siderophore transport
H1I73_RS00785	COG0426	domain, Protein
H1I73_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I73_RS00830	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS00835	COG1519	Transferase
H1I73_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I73_RS00845	COG0668	transmembrane transport
H1I73_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS00860	COG1335	isochorismatase
H1I73_RS00865	COG1522	sequence-specific DNA binding
H1I73_RS00870	COG3328	transposase activity
H1I73_RS00895	COG2198	Histidine kinase
H1I73_RS00895	COG0784	Response regulator, receiver
H1I73_RS00895	COG2205	protein histidine kinase activity
H1I73_RS00900	COG3162	membrane
H1I73_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I73_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I73_RS00940	COG1309	transcriptional regulator
H1I73_RS00960	COG0351	phosphomethylpyrimidine kinase
H1I73_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I73_RS00970	COG2814	Major facilitator Superfamily
H1I73_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I73_RS00995	COG1113	amino acid transport
H1I73_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS01020	COG1335	isochorismatase
H1I73_RS01050	COG2814	Major facilitator Superfamily
H1I73_RS01055	COG0583	DNA-binding transcription factor activity
H1I73_RS01075	COG0667	Aldo Keto reductase
H1I73_RS01110	COG1733	regulation of RNA biosynthetic process
H1I73_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I73_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
H1I73_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I73_RS01255	COG0427	acetyl-CoA hydrolase
H1I73_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS01285	COG4221	oxidoreductase activity
H1I73_RS01290	COG2873	o-acetylhomoserine
H1I73_RS01380	COG0833	amino acid
H1I73_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I73_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I73_RS01445	COG2226	methyltransferase
H1I73_RS01495	COG0067	glutamate synthase
H1I73_RS01495	COG0069	glutamate synthase activity
H1I73_RS01495	COG0070	glutamate synthase
H1I73_RS01500	COG0493	'glutamate synthase
H1I73_RS01510	COG1704	LemA family
H1I73_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I73_RS01535	COG3307	-O-antigen
H1I73_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I73_RS01570	COG0194	GDP metabolic process
H1I73_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I73_RS01640	COG5380	lipid catabolic process
H1I73_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I73_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I73_RS01675	COG0277	FAD linked oxidase domain protein
H1I73_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I73_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS01705	COG1289	transmembrane transporter activity
H1I73_RS01715	COG0628	permease
H1I73_RS01720	COG1192	Involved in chromosome partitioning
H1I73_RS01750	COG0833	amino acid
H1I73_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I73_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I73_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS01810	COG0583	DNA-binding transcription factor activity
H1I73_RS01855	COG0517	IMP dehydrogenase activity
H1I73_RS01860	COG1983	PspC domain protein
H1I73_RS01870	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS01885	COG0408	coproporphyrinogen oxidase activity
H1I73_RS01905	COG0513	Belongs to the DEAD box helicase family
H1I73_RS01915	COG1127	ABC transporter
H1I73_RS01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I73_RS01930	COG2854	intermembrane phospholipid transfer
H1I73_RS01940	COG0598	Magnesium transport protein CorA
H1I73_RS01950	COG0494	nUDIX hydrolase
H1I73_RS01955	COG1040	competence protein
H1I73_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I73_RS01980	COG1946	Acyl-CoA thioesterase
H1I73_RS01985	COG1301	dicarboxylic acid transport
H1I73_RS02000	COG1959	2 iron, 2 sulfur cluster binding
H1I73_RS02005	COG1017	nitric oxide dioxygenase activity
H1I73_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS02010	COG0433	COG0433 Predicted ATPase
H1I73_RS02015	COG0626	cystathionine gamma-synthase activity
H1I73_RS02170	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I73_RS02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I73_RS02210	COG0339	signal peptide processing
H1I73_RS02215	COG0557	exoribonuclease II activity
H1I73_RS02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I73_RS02265	COG2169	Transcriptional regulator
H1I73_RS02270	COG0697	spore germination
H1I73_RS02275	COG1295	ribonuclease BN
H1I73_RS02310	COG1702	phosphate starvation-inducible protein PhoH
H1I73_RS02320	COG0739	heme binding
H1I73_RS02320	COG0741	lytic transglycosylase activity
H1I73_RS02320	COG1196	nuclear chromosome segregation
H1I73_RS02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I73_RS02355	COG1183	phosphatidylcholine synthase activity
H1I73_RS02400	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02405	COG1309	transcriptional regulator
H1I73_RS02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I73_RS02425	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02445	COG2969	positive regulation of protein catabolic process
H1I73_RS02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I73_RS02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I73_RS02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I73_RS02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I73_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I73_RS02510	COG1408	metallophosphoesterase
H1I73_RS02520	COG2199	diguanylate cyclase activity
H1I73_RS02580	COG1607	acyl-coa hydrolase
H1I73_RS02610	COG2350	Protein conserved in bacteria
H1I73_RS02620	COG0613	PHP domain protein
H1I73_RS02625	COG3781	membrane
H1I73_RS02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I73_RS02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I73_RS02650	COG1862	Preprotein translocase
H1I73_RS02680	COG2205	protein histidine kinase activity
H1I73_RS02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I73_RS02705	COG0726	polysaccharide deacetylase
H1I73_RS02710	COG0463	Glycosyl transferase, family 2
H1I73_RS02715	COG0438	transferase activity, transferring glycosyl groups
H1I73_RS02780	COG0625	glutathione transferase activity
H1I73_RS02785	COG0583	DNA-binding transcription factor activity
H1I73_RS02790	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02795	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS02805	COG2205	protein histidine kinase activity
H1I73_RS02810	COG0745	RESPONSE REGULATOR receiver
H1I73_RS02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I73_RS02835	COG2096	Adenosyltransferase
H1I73_RS02885	COG0285	dihydrofolate synthase activity
H1I73_RS02905	COG0450	alkyl hydroperoxide reductase
H1I73_RS02920	COG0477	Major facilitator Superfamily
H1I73_RS02925	COG1272	protein, Hemolysin III
H1I73_RS02955	COG0183	Belongs to the thiolase family
H1I73_RS02960	COG2207	Transcriptional regulator
H1I73_RS02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS03000	COG0183	Belongs to the thiolase family
H1I73_RS03010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I73_RS03010	COG2885	chlorophyll binding
H1I73_RS03020	COG1690	Belongs to the RtcB family
H1I73_RS03025	COG0833	amino acid
H1I73_RS03035	COG2233	PERMEase
H1I73_RS03040	COG1217	gtp-binding protein TYPA
H1I73_RS03065	COG2094	Belongs to the DNA glycosylase MPG family
H1I73_RS03085	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS03105	COG0354	folic acid binding
H1I73_RS03115	COG3189	MarR family transcriptional regulator
H1I73_RS03120	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I73_RS03125	COG3422	double-strand break repair
H1I73_RS03165	COG0840	transmembrane signaling receptor activity
H1I73_RS03185	COG5510	response to toxic substance
H1I73_RS03195	COG2832	Protein of unknown function (DUF454)
H1I73_RS03200	COG1376	ErfK ybiS ycfS ynhG family protein
H1I73_RS03240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I73_RS03250	COG1289	transmembrane transporter activity
H1I73_RS03255	COG2814	Major facilitator Superfamily
H1I73_RS03275	COG1115	amino acid carrier protein
H1I73_RS03280	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I73_RS03285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I73_RS03290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I73_RS03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I73_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I73_RS03345	COG1077	Cell shape determining protein MreB Mrl
H1I73_RS03350	COG1792	Involved in formation and maintenance of cell shape
H1I73_RS03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I73_RS03360	COG0424	maF-like protein
H1I73_RS03365	COG1530	ribonuclease E activity
H1I73_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS03385	COG0560	Phosphoserine phosphatase
H1I73_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS03420	COG2207	Transcriptional regulator
H1I73_RS03440	COG1113	amino acid transport
H1I73_RS03445	COG2828	Protein conserved in bacteria
H1I73_RS03450	COG0142	geranyltranstransferase activity
H1I73_RS03455	COG2315	Protein conserved in bacteria
H1I73_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I73_RS03500	COG0745	RESPONSE REGULATOR receiver
H1I73_RS03505	COG0642	Histidine kinase
H1I73_RS03515	COG0004	ammonium transporteR
H1I73_RS03520	COG0583	DNA-binding transcription factor activity
H1I73_RS03540	COG0525	valine-tRNA ligase activity
H1I73_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS03560	COG0393	Putative heavy-metal-binding
H1I73_RS03565	COG0393	Putative heavy-metal-binding
H1I73_RS03570	COG1538	Outer membrane efflux protein
H1I73_RS03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS03585	COG0671	phosphoesterase, PA-phosphatase related
H1I73_RS03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I73_RS03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I73_RS03630	COG1648	precorrin-2 dehydrogenase activity
H1I73_RS03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I73_RS03640	COG1733	regulation of RNA biosynthetic process
H1I73_RS03650	COG0531	amino acid
H1I73_RS03665	COG0321	lipoyl(octanoyl) transferase activity
H1I73_RS03670	COG2921	Belongs to the UPF0250 family
H1I73_RS03710	COG2009	succinate dehydrogenase
H1I73_RS03715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I73_RS03720	COG1053	succinate dehydrogenase
H1I73_RS03725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I73_RS03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS03770	COG2354	Protein conserved in bacteria
H1I73_RS03775	COG2321	neutral zinc metallopeptidase
H1I73_RS03795	COG2843	Capsule synthesis protein
H1I73_RS03810	COG0589	response to stress
H1I73_RS03855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I73_RS03860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I73_RS03910	COG0477	Major facilitator Superfamily
H1I73_RS03915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I73_RS03930	COG1597	lipid kinase activity
H1I73_RS03935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I73_RS03965	COG0584	glycerophosphoryl diester phosphodiesterase
H1I73_RS03985	COG0741	lytic transglycosylase activity
H1I73_RS04005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I73_RS04020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS04050	COG0778	Nitroreductase
H1I73_RS04065	COG1929	Belongs to the glycerate kinase type-1 family
H1I73_RS04070	COG0243	molybdopterin cofactor binding
H1I73_RS04075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I73_RS04080	COG3339	Conserved Protein
H1I73_RS04090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I73_RS04105	COG1113	amino acid transport
H1I73_RS04115	COG0019	diaminopimelate decarboxylase activity
H1I73_RS04125	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS04130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I73_RS04160	COG0463	Glycosyl transferase, family 2
H1I73_RS04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS04215	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I73_RS04220	COG1136	(ABC) transporter
H1I73_RS04225	COG0658	competence protein
H1I73_RS04225	COG2333	competence protein COMEC
H1I73_RS04235	COG0616	signal peptide processing
H1I73_RS04235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I73_RS04240	COG0596	Alpha beta hydrolase
H1I73_RS04245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I73_RS04255	COG0628	permease
H1I73_RS04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I73_RS04310	COG0823	Involved in the tonB-independent uptake of proteins
H1I73_RS04330	COG0824	Thioesterase
H1I73_RS04335	COG1473	amidohydrolase
H1I73_RS04355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I73_RS04355	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I73_RS04360	COG2814	Major facilitator Superfamily
H1I73_RS04370	COG1024	Enoyl-CoA hydratase
H1I73_RS04375	COG1056	cytidyltransferase-related domain
H1I73_RS04375	COG1051	belongs to the nudix hydrolase family
H1I73_RS04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I73_RS04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I73_RS04415	COG4625	pathogenesis
H1I73_RS04420	COG0583	DNA-binding transcription factor activity
H1I73_RS04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I73_RS04430	COG4208	sulfate ABC transporter
H1I73_RS04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I73_RS04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I73_RS04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I73_RS04490	COG0681	Belongs to the peptidase S26 family
H1I73_RS04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I73_RS04515	COG1381	Involved in DNA repair and RecF pathway recombination
H1I73_RS04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I73_RS04530	COG4221	oxidoreductase activity
H1I73_RS04560	COG0436	Aminotransferase
H1I73_RS04580	COG0556	nucleotide-excision repair
H1I73_RS04635	COG2070	2-Nitropropane dioxygenase
H1I73_RS04665	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS04680	COG0415	Belongs to the DNA photolyase family
H1I73_RS04690	COG1252	NADH dehydrogenase
H1I73_RS04695	COG1686	Belongs to the peptidase S11 family
H1I73_RS04710	COG1187	pseudouridine synthase activity
H1I73_RS04735	COG0477	Major facilitator Superfamily
H1I73_RS04740	COG0583	DNA-binding transcription factor activity
H1I73_RS04745	COG1823	symporter activity
H1I73_RS04755	COG0612	Peptidase, M16
H1I73_RS04780	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS04830	COG1309	transcriptional regulator
H1I73_RS04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I73_RS04845	COG0076	glutamate decarboxylase activity
H1I73_RS04855	COG1522	sequence-specific DNA binding
H1I73_RS04860	COG3961	Belongs to the TPP enzyme family
H1I73_RS04865	COG1113	amino acid transport
H1I73_RS04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I73_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
H1I73_RS04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I73_RS04890	COG0616	signal peptide processing
H1I73_RS04900	COG3328	transposase activity
H1I73_RS04930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I73_RS04935	COG1686	Belongs to the peptidase S11 family
H1I73_RS04960	COG0583	DNA-binding transcription factor activity
H1I73_RS04965	COG1067	ATP-dependent peptidase activity
H1I73_RS05010	COG1966	Carbon starvation protein
H1I73_RS05015	COG2879	small protein
H1I73_RS05050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I73_RS05050	COG2508	Transcriptional regulator
H1I73_RS05070	COG1113	amino acid transport
H1I73_RS05075	COG0583	DNA-binding transcription factor activity
H1I73_RS05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS05105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS05110	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I73_RS05110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS05145	COG2814	Major facilitator Superfamily
H1I73_RS05150	COG4948	Mandelate Racemase Muconate Lactonizing
H1I73_RS05160	COG1309	transcriptional regulator
H1I73_RS05180	COG1741	Belongs to the pirin family
H1I73_RS05190	COG2964	Protein conserved in bacteria
H1I73_RS05205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS05210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I73_RS05215	COG4605	iron ion homeostasis
H1I73_RS05220	COG4604	ABC transporter, ATP-binding protein
H1I73_RS05225	COG4607	ABC-type enterochelin transport system periplasmic component
H1I73_RS05230	COG4774	siderophore transport
H1I73_RS05240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I73_RS05245	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I73_RS05250	COG3433	isochorismatase activity
H1I73_RS05250	COG1535	isochorismatase
H1I73_RS05265	COG1132	(ABC) transporter
H1I73_RS05270	COG1132	(ABC) transporter
H1I73_RS05275	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I73_RS05285	COG1169	isochorismate synthase
H1I73_RS05300	COG3739	integral membrane protein
H1I73_RS05325	COG0302	gtp cyclohydrolase
H1I73_RS05335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I73_RS05365	COG0308	aminopeptidase N
H1I73_RS05370	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I73_RS05385	COG0174	glutamine synthetase
H1I73_RS05430	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I73_RS05435	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I73_RS05440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I73_RS05460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I73_RS05465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I73_RS05470	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I73_RS05485	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS05490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I73_RS05495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS05505	COG2223	nitrite transmembrane transporter activity
H1I73_RS05515	COG0024	Methionine aminopeptidase
H1I73_RS05520	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I73_RS05535	COG2207	Transcriptional regulator
H1I73_RS05565	COG0772	Belongs to the SEDS family
H1I73_RS05580	COG0842	Transport permease protein
H1I73_RS05585	COG1131	(ABC) transporter
H1I73_RS05630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS05645	COG4215	(ABC) transporter
H1I73_RS05650	COG4160	amino acid transport
H1I73_RS05655	COG4598	ABC transporter
H1I73_RS05665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I73_RS05670	COG0826	peptidase U32
H1I73_RS05675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS05690	COG1720	tRNA m6t6A37 methyltransferase activity
H1I73_RS05700	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I73_RS05715	COG0642	Histidine kinase
H1I73_RS05725	COG0494	nUDIX hydrolase
H1I73_RS05735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I73_RS05740	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I73_RS05745	COG3139	Protein of unknown function (DUF1315)
H1I73_RS05750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I73_RS05755	COG1301	dicarboxylic acid transport
H1I73_RS05760	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS05765	COG2819	hydrolase of the alpha beta superfamily
H1I73_RS05775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I73_RS05785	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I73_RS05790	COG1234	tRNA 3'-trailer cleavage
H1I73_RS05820	COG2363	Small membrane protein
H1I73_RS05845	COG0513	Belongs to the DEAD box helicase family
H1I73_RS05855	COG0778	Nitroreductase
H1I73_RS05885	COG1286	toxin biosynthetic process
H1I73_RS05910	COG4783	chaperone-mediated protein folding
H1I73_RS05915	COG1610	YqeY-like protein
H1I73_RS06015	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I73_RS06040	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I73_RS06045	COG0786	glutamate:sodium symporter activity
H1I73_RS06055	COG2186	Transcriptional regulator
H1I73_RS06105	COG0477	Major facilitator Superfamily
H1I73_RS06145	COG2995	paraquat-inducible protein a
H1I73_RS06150	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I73_RS06150	COG3008	intermembrane lipid transfer
H1I73_RS06180	COG0488	(ABC) transporter
H1I73_RS06185	COG3173	Aminoglycoside phosphotransferase
H1I73_RS06195	COG2433	Pfam Transposase IS66
H1I73_RS06235	COG1301	dicarboxylic acid transport
H1I73_RS06245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS06250	COG2011	ABC-type metal ion transport system permease component
H1I73_RS06255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I73_RS06260	COG1464	Belongs to the NlpA lipoprotein family
H1I73_RS06265	COG0151	Belongs to the GarS family
H1I73_RS06270	COG0138	bifunctional purine biosynthesis protein purh
H1I73_RS06275	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I73_RS06305	COG2308	Evidence 4 Homologs of previously reported genes of
H1I73_RS06315	COG1305	Transglutaminase-like
H1I73_RS06325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I73_RS06330	COG0305	Participates in initiation and elongation during chromosome replication
H1I73_RS06355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I73_RS06365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I73_RS06370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I73_RS06395	COG0726	polysaccharide deacetylase
H1I73_RS06395	COG1649	PFAM Uncharacterised BCR, COG1649
H1I73_RS06400	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS06405	COG3658	cytochrome
H1I73_RS06415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS06430	COG0583	DNA-binding transcription factor activity
H1I73_RS06450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS06455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS06470	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS06475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS06480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS06505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I73_RS06510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I73_RS06520	COG2205	protein histidine kinase activity
H1I73_RS06525	COG0745	RESPONSE REGULATOR receiver
H1I73_RS06550	COG0729	surface antigen
H1I73_RS06575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I73_RS06580	COG2814	Major facilitator Superfamily
H1I73_RS06595	COG0583	DNA-binding transcription factor activity
H1I73_RS06610	COG1187	pseudouridine synthase activity
H1I73_RS06630	COG0802	atpase or kinase
H1I73_RS06635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I73_RS06645	COG1923	regulation of RNA biosynthetic process
H1I73_RS06650	COG0697	spore germination
H1I73_RS06665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I73_RS06675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I73_RS06680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I73_RS06680	COG0519	Catalyzes the synthesis of GMP from XMP
H1I73_RS06685	COG4302	ethanolamine ammonia-lyase activity
H1I73_RS06690	COG4303	Ethanolamine ammonia lyase large subunit
H1I73_RS06695	COG0531	amino acid
H1I73_RS06715	COG1454	alcohol dehydrogenase
H1I73_RS06720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I73_RS06730	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I73_RS06750	COG0308	aminopeptidase N
H1I73_RS06780	COG1605	Chorismate mutase
H1I73_RS06800	COG1309	transcriptional regulator
H1I73_RS06810	COG0668	transmembrane transport
H1I73_RS06845	COG4773	Receptor
H1I73_RS06865	COG0488	(ABC) transporter
H1I73_RS06870	COG0589	response to stress
H1I73_RS06915	COG3135	benzoate transporter
H1I73_RS06920	COG1522	sequence-specific DNA binding
H1I73_RS06930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I73_RS06935	COG0583	DNA-binding transcription factor activity
H1I73_RS06945	COG0183	Belongs to the thiolase family
H1I73_RS06955	COG2030	dehydratase
H1I73_RS06960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I73_RS06975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I73_RS06985	COG0824	Thioesterase
H1I73_RS06990	COG1454	alcohol dehydrogenase
H1I73_RS07000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I73_RS07020	COG0069	glutamate synthase activity
H1I73_RS07185	COG5410	chromosome segregation
H1I73_RS07370	COG2814	Major facilitator Superfamily
H1I73_RS07385	COG0511	ligase activity, forming carbon-carbon bonds
H1I73_RS07405	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS07405	COG1116	anion transmembrane transporter activity
H1I73_RS07410	COG0745	RESPONSE REGULATOR receiver
H1I73_RS07420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS07420	COG2146	nitrite reductase [NAD(P)H] activity
H1I73_RS07425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS07430	COG0243	molybdopterin cofactor binding
H1I73_RS07440	COG0243	molybdopterin cofactor binding
H1I73_RS07445	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I73_RS07460	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I73_RS07460	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I73_RS07465	COG0303	'Molybdopterin
H1I73_RS07475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS07480	COG0697	spore germination
H1I73_RS07500	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I73_RS07505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I73_RS07560	COG2204	response regulator
H1I73_RS07565	COG3852	Histidine kinase
H1I73_RS07585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I73_RS07590	COG0575	Belongs to the CDS family
H1I73_RS07645	COG2137	regulation of response to DNA damage stimulus
H1I73_RS07655	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I73_RS07660	COG1011	Hydrolase
H1I73_RS07685	COG1522	sequence-specific DNA binding
H1I73_RS07695	COG1113	amino acid transport
H1I73_RS07715	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS07720	COG2135	peptidase activity
H1I73_RS07735	COG5001	Diguanylate cyclase
H1I73_RS07735	COG3300	MHYT domain
H1I73_RS07755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I73_RS07755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I73_RS07755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I73_RS07760	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I73_RS07765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I73_RS07765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I73_RS07795	COG0024	Methionine aminopeptidase
H1I73_RS07800	COG0583	DNA-binding transcription factor activity
H1I73_RS07810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I73_RS07815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I73_RS07820	COG0516	GMP reductase activity
H1I73_RS07820	COG0517	IMP dehydrogenase activity
H1I73_RS07855	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I73_RS07870	COG4890	Cyd operon protein YbgT
H1I73_RS07875	COG1294	oxidase, subunit
H1I73_RS07890	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I73_RS07900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I73_RS07905	COG4774	siderophore transport
H1I73_RS07920	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I73_RS07925	COG0569	domain protein
H1I73_RS07930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I73_RS07960	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I73_RS07965	COG0542	response to heat
H1I73_RS07990	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS07990	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS08035	COG2323	membrane
H1I73_RS08040	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I73_RS08050	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS08055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS08060	COG0183	Belongs to the thiolase family
H1I73_RS08065	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I73_RS08070	COG0596	Alpha beta hydrolase
H1I73_RS08075	COG2271	Major facilitator Superfamily
H1I73_RS08080	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I73_RS08085	COG3485	protocatechuate 3,4-dioxygenase
H1I73_RS08095	COG0710	3-dehydroquinate dehydratase activity
H1I73_RS08100	COG3420	alginic acid biosynthetic process
H1I73_RS08105	COG3659	wide pore channel activity
H1I73_RS08110	COG4993	Dehydrogenase
H1I73_RS08120	COG2391	methyltransferase activity
H1I73_RS08135	COG1414	Transcriptional regulator
H1I73_RS08140	COG0583	DNA-binding transcription factor activity
H1I73_RS08145	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS08170	COG2814	Major facilitator Superfamily
H1I73_RS08180	COG0154	amidase activity
H1I73_RS08200	COG4638	Rieske (2fe-2S)
H1I73_RS08210	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS08220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS08230	COG3733	amine oxidase
H1I73_RS08240	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS08255	COG0183	Belongs to the thiolase family
H1I73_RS08260	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS08265	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS08275	COG4829	muconolactone delta-isomerase
H1I73_RS08280	COG4948	Mandelate Racemase Muconate Lactonizing
H1I73_RS08285	COG0583	DNA-binding transcription factor activity
H1I73_RS08295	COG2186	Transcriptional regulator
H1I73_RS08335	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS08355	COG3162	membrane
H1I73_RS08370	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08385	COG0753	catalase activity
H1I73_RS08405	COG1846	Transcriptional regulator
H1I73_RS08410	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS08410	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS08420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I73_RS08450	COG1309	transcriptional regulator
H1I73_RS08460	COG1335	isochorismatase
H1I73_RS08465	COG0583	DNA-binding transcription factor activity
H1I73_RS08475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS08475	COG0475	glutathione-regulated potassium exporter activity
H1I73_RS08485	COG1473	amidohydrolase
H1I73_RS08495	COG2831	hemolysin activation secretion protein
H1I73_RS08500	COG3210	domain, Protein
H1I73_RS08530	COG2188	Transcriptional regulator
H1I73_RS08545	COG0583	DNA-binding transcription factor activity
H1I73_RS08575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I73_RS08605	COG1566	PFAM secretion protein HlyD family protein
H1I73_RS08620	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS08625	COG0129	dihydroxy-acid dehydratase activity
H1I73_RS08635	COG0583	DNA-binding transcription factor activity
H1I73_RS08640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I73_RS08650	COG2084	Dehydrogenase
H1I73_RS08655	COG2207	Transcriptional regulator
H1I73_RS08670	COG1064	alcohol dehydrogenase
H1I73_RS08680	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I73_RS08685	COG1120	ATPase activity
H1I73_RS08705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I73_RS08825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I73_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS08890	COG2207	Transcriptional regulator
H1I73_RS08900	COG2205	protein histidine kinase activity
H1I73_RS08905	COG0745	RESPONSE REGULATOR receiver
H1I73_RS08910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS08915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I73_RS08920	COG1538	Outer membrane efflux protein
H1I73_RS08930	COG2072	flavoprotein involved in K transport
H1I73_RS08950	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS08970	COG3539	Fimbrial protein
H1I73_RS09000	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I73_RS09010	COG0753	catalase activity
H1I73_RS09025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I73_RS09085	COG1535	isochorismatase
H1I73_RS09085	COG3433	isochorismatase activity
H1I73_RS09090	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09095	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I73_RS09100	COG4149	molybdate abc transporter
H1I73_RS09105	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I73_RS09115	COG4638	Rieske (2fe-2S)
H1I73_RS09120	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I73_RS09125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I73_RS09125	COG0543	2 iron, 2 sulfur cluster binding
H1I73_RS09150	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09165	COG2207	Transcriptional regulator
H1I73_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS09180	COG2610	gluconate transmembrane transporter activity
H1I73_RS09190	COG0583	DNA-binding transcription factor activity
H1I73_RS09200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS09205	COG2031	fatty acid transporter
H1I73_RS09210	COG0183	Belongs to the thiolase family
H1I73_RS09215	COG0583	DNA-binding transcription factor activity
H1I73_RS09220	COG0583	DNA-binding transcription factor activity
H1I73_RS09235	COG1027	Aspartate ammonia-lyase
H1I73_RS09245	COG0477	Major facilitator Superfamily
H1I73_RS09265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS09270	COG4521	taurine ABC transporter
H1I73_RS09285	COG2188	Transcriptional regulator
H1I73_RS09295	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I73_RS09300	COG1733	regulation of RNA biosynthetic process
H1I73_RS09305	COG3708	Transcriptional regulator
H1I73_RS09305	COG2207	Transcriptional regulator
H1I73_RS09320	COG0730	response to heat
H1I73_RS09335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS09335	COG3453	Protein conserved in bacteria
H1I73_RS09345	COG3781	membrane
H1I73_RS09350	COG1063	alcohol dehydrogenase
H1I73_RS09360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I73_RS09365	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I73_RS09370	COG0022	dehydrogenase e1 component
H1I73_RS09375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I73_RS09380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I73_RS09395	COG3706	GGDEF domain
H1I73_RS09410	COG0133	tryptophan synthase activity
H1I73_RS09420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I73_RS09455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I73_RS09480	COG2226	methyltransferase
H1I73_RS09535	COG0842	Transport permease protein
H1I73_RS09540	COG0842	Transport permease protein
H1I73_RS09545	COG1131	(ABC) transporter
H1I73_RS09560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I73_RS09565	COG4773	Receptor
H1I73_RS09585	COG0730	response to heat
H1I73_RS09590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I73_RS09610	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I73_RS09625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I73_RS09665	COG4264	IucA IucC family
H1I73_RS09670	COG4264	IucA IucC family
H1I73_RS09690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I73_RS09705	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS09710	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS09715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I73_RS09720	COG2207	Transcriptional regulator
H1I73_RS09725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I73_RS09730	COG0776	regulation of translation
H1I73_RS09755	COG0822	iron-sulfur transferase activity
H1I73_RS09760	COG0316	Belongs to the HesB IscA family
H1I73_RS09790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I73_RS09810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I73_RS09815	COG0702	epimerase
H1I73_RS09850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I73_RS09860	COG0339	signal peptide processing
H1I73_RS09910	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I73_RS09915	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I73_RS09945	COG0776	regulation of translation
H1I73_RS10010	COG0084	hydrolase, TatD family'
H1I73_RS10030	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I73_RS10035	COG1132	(ABC) transporter
H1I73_RS10045	COG0811	peptide transport
H1I73_RS10050	COG1475	DNA binding
H1I73_RS10055	COG1192	Involved in chromosome partitioning
H1I73_RS10065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I73_RS10080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I73_RS10085	COG0191	fructose-bisphosphate aldolase activity
H1I73_RS10105	COG0424	maF-like protein
H1I73_RS10110	COG2850	peptidyl-arginine hydroxylation
H1I73_RS10120	COG0640	Transcriptional regulator
H1I73_RS10135	COG3619	membrane
H1I73_RS10145	COG1132	(ABC) transporter
H1I73_RS10165	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I73_RS10170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I73_RS10180	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I73_RS10180	COG0506	proline dehydrogenase activity
H1I73_RS10180	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I73_RS10185	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I73_RS10200	COG3698	Phosphodiester glycosidase
H1I73_RS10210	COG2353	YceI-like domain
H1I73_RS10220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I73_RS10265	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I73_RS10265	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I73_RS10290	COG3539	Fimbrial protein
H1I73_RS10295	COG3121	Chaperone
H1I73_RS10320	COG0697	spore germination
H1I73_RS10330	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I73_RS10340	COG0583	DNA-binding transcription factor activity
H1I73_RS10360	COG1309	transcriptional regulator
H1I73_RS10375	COG1522	sequence-specific DNA binding
H1I73_RS10385	COG1126	abc transporter atp-binding protein
H1I73_RS10390	COG0765	amino acid transport
H1I73_RS10395	COG0765	amino acid transport
H1I73_RS10425	COG1464	Belongs to the NlpA lipoprotein family
H1I73_RS10435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I73_RS10440	COG2011	ABC-type metal ion transport system permease component
H1I73_RS10445	COG0012	GTP binding
H1I73_RS10470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I73_RS10510	COG0386	Belongs to the glutathione peroxidase family
H1I73_RS10520	COG0436	Aminotransferase
H1I73_RS10575	COG0583	DNA-binding transcription factor activity
H1I73_RS10580	COG0798	PFAM Bile acid sodium symporter
H1I73_RS10585	COG0640	Transcriptional regulator
H1I73_RS10600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I73_RS10610	COG0583	DNA-binding transcription factor activity
H1I73_RS10620	COG1953	Uracil, thiamine, allantoin
H1I73_RS10630	COG2175	clavaminate synthase activity
H1I73_RS10635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS10640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I73_RS10645	COG4521	taurine ABC transporter
H1I73_RS10655	COG0477	Major facilitator Superfamily
H1I73_RS10675	COG1271	oxidase subunit
H1I73_RS10680	COG1294	oxidase, subunit
H1I73_RS10690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I73_RS10710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I73_RS10730	COG3052	prosthetic group binding
H1I73_RS10735	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I73_RS10745	COG2814	Major facilitator Superfamily
H1I73_RS10765	COG1346	cytolysis
H1I73_RS10775	COG0583	DNA-binding transcription factor activity
H1I73_RS10780	COG0625	glutathione transferase activity
H1I73_RS10785	COG0625	glutathione transferase activity
H1I73_RS10790	COG0583	DNA-binding transcription factor activity
H1I73_RS10805	COG1045	serine acetyltransferase
H1I73_RS10810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I73_RS10815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I73_RS10825	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS10840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS10845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS10850	COG1126	abc transporter atp-binding protein
H1I73_RS10855	COG0765	amino acid transport
H1I73_RS10860	COG0765	amino acid transport
H1I73_RS10900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I73_RS10920	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS10970	COG0583	DNA-binding transcription factor activity
H1I73_RS10995	COG1309	transcriptional regulator
H1I73_RS11000	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I73_RS11010	COG1024	Enoyl-CoA hydratase
H1I73_RS11015	COG4770	biotin carboxylase activity
H1I73_RS11025	COG0583	DNA-binding transcription factor activity
H1I73_RS11040	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11050	COG2814	Major facilitator Superfamily
H1I73_RS11060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I73_RS11065	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I73_RS11070	COG2814	Major facilitator Superfamily
H1I73_RS11075	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11080	COG1024	Enoyl-CoA hydratase
H1I73_RS11085	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS11090	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11095	COG0183	Belongs to the thiolase family
H1I73_RS11105	COG2814	Major facilitator Superfamily
H1I73_RS11115	COG1024	Enoyl-CoA hydratase
H1I73_RS11130	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS11135	COG2814	Major facilitator Superfamily
H1I73_RS11140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I73_RS11145	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I73_RS11160	COG3842	ATPase activity
H1I73_RS11165	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I73_RS11175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS11180	COG1414	Transcriptional regulator
H1I73_RS11190	COG0583	DNA-binding transcription factor activity
H1I73_RS11195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I73_RS11200	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11210	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I73_RS11220	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS11230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS11235	COG2267	carboxylic ester hydrolase activity
H1I73_RS11255	COG3038	cytochrome b561
H1I73_RS11260	COG0753	catalase activity
H1I73_RS11295	COG2050	protein possibly involved in aromatic compounds catabolism
H1I73_RS11305	COG3327	negative regulation of DNA-templated transcription, initiation
H1I73_RS11310	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I73_RS11315	COG0183	Belongs to the thiolase family
H1I73_RS11320	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11325	COG1024	Enoyl-CoA hydratase
H1I73_RS11330	COG1024	Enoyl-CoA hydratase
H1I73_RS11340	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I73_RS11345	COG3396	Phenylacetate-CoA oxygenase
H1I73_RS11350	COG3460	Phenylacetate-CoA oxygenase
H1I73_RS11355	COG3396	Phenylacetate-CoA oxygenase
H1I73_RS11360	COG2030	dehydratase
H1I73_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11365	COG1760	l-serine dehydratase
H1I73_RS11370	COG0531	amino acid
H1I73_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS11390	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS11400	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I73_RS11420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS11430	COG0789	Transcriptional regulator
H1I73_RS11445	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I73_RS11460	COG2807	transmembrane transport
H1I73_RS11465	COG0590	tRNA wobble adenosine to inosine editing
H1I73_RS11585	COG1116	anion transmembrane transporter activity
H1I73_RS11590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I73_RS11600	COG0864	Transcriptional regulator
H1I73_RS11620	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS11625	COG0439	Biotin carboxylase
H1I73_RS11640	COG1063	alcohol dehydrogenase
H1I73_RS11650	COG1309	transcriptional regulator
H1I73_RS11670	COG0038	chloride channel
H1I73_RS11695	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I73_RS11700	COG0583	DNA-binding transcription factor activity
H1I73_RS11750	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I73_RS11770	COG2814	Major facilitator Superfamily
H1I73_RS11785	COG1560	Kdo2-lipid A biosynthetic process
H1I73_RS11795	COG5006	permease, DMT superfamily
H1I73_RS11800	COG1522	sequence-specific DNA binding
H1I73_RS11815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I73_RS11825	COG4122	O-methyltransferase activity
H1I73_RS11855	COG1538	Outer membrane efflux protein
H1I73_RS11860	COG1137	ATPase activity
H1I73_RS11865	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I73_RS11875	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I73_RS11880	COG0517	IMP dehydrogenase activity
H1I73_RS11880	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I73_RS11915	COG2814	Major facilitator Superfamily
H1I73_RS11950	COG1278	Cold shock
H1I73_RS11955	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS11985	COG1570	exodeoxyribonuclease VII activity
H1I73_RS12035	COG0583	DNA-binding transcription factor activity
H1I73_RS12045	COG4638	Rieske (2fe-2S)
H1I73_RS12050	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I73_RS12055	COG0543	2 iron, 2 sulfur cluster binding
H1I73_RS12055	COG0633	Ferredoxin
H1I73_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS12065	COG3135	benzoate transporter
H1I73_RS12070	COG2814	Major facilitator Superfamily
H1I73_RS12085	COG1643	Atp-dependent helicase
H1I73_RS12090	COG0450	alkyl hydroperoxide reductase
H1I73_RS12100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I73_RS12130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I73_RS12135	COG0625	glutathione transferase activity
H1I73_RS12145	COG2885	chlorophyll binding
H1I73_RS12180	COG0542	response to heat
H1I73_RS12195	COG1765	OsmC-like protein
H1I73_RS12215	COG0667	Aldo Keto reductase
H1I73_RS12230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I73_RS12240	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I73_RS12250	COG0527	aspartate kinase activity
H1I73_RS12260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I73_RS12270	COG3038	cytochrome b561
H1I73_RS12275	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I73_RS12280	COG2252	PERMEase
H1I73_RS12290	COG2072	flavoprotein involved in K transport
H1I73_RS12305	COG1741	Belongs to the pirin family
H1I73_RS12310	COG1309	transcriptional regulator
H1I73_RS12330	COG1902	pentaerythritol trinitrate reductase activity
H1I73_RS12330	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS12340	COG3706	GGDEF domain
H1I73_RS12340	COG4251	negative regulation of phosphorylation
H1I73_RS12340	COG2203	Gaf domain
H1I73_RS12340	COG5001	Diguanylate cyclase
H1I73_RS12350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS12370	COG4172	Belongs to the ABC transporter superfamily
H1I73_RS12375	COG4239	(ABC) transporter, permease
H1I73_RS12380	COG4174	ABC transporter (Permease)
H1I73_RS12390	COG0741	lytic transglycosylase activity
H1I73_RS12390	COG1388	LysM domain
H1I73_RS12390	COG1388	LysM domain
H1I73_RS12390	COG0741	lytic transglycosylase activity
H1I73_RS12395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS12435	COG0583	DNA-binding transcription factor activity
H1I73_RS12440	COG1279	arginine transmembrane transporter activity
H1I73_RS12460	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS12465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS12470	COG0006	proline dipeptidase activity
H1I73_RS12885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I73_RS12910	COG3384	dioxygenase
H1I73_RS12920	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I73_RS12925	COG2878	Part of a membrane complex involved in electron transport
H1I73_RS12930	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I73_RS12955	COG0768	penicillin binding
H1I73_RS12960	COG0742	ribosomal rna small subunit methyltransferase
H1I73_RS12975	COG0830	nickel cation binding
H1I73_RS12985	COG0804	urea catabolic process
H1I73_RS13025	COG1253	flavin adenine dinucleotide binding
H1I73_RS13030	COG2851	Citrate transporter
H1I73_RS13085	COG1773	rubredoxin
H1I73_RS13090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I73_RS13100	COG0583	DNA-binding transcription factor activity
H1I73_RS13125	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I73_RS13130	COG4181	ATPase activity
H1I73_RS13175	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I73_RS13195	COG0306	phosphate transporter
H1I73_RS13205	COG3958	Transketolase
H1I73_RS13210	COG3959	Transketolase, thiamine diphosphate binding domain
H1I73_RS13215	COG2271	Major facilitator Superfamily
H1I73_RS13220	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13225	COG0583	DNA-binding transcription factor activity
H1I73_RS13240	COG2223	nitrite transmembrane transporter activity
H1I73_RS13245	COG2207	Transcriptional regulator
H1I73_RS13250	COG2066	Belongs to the glutaminase family
H1I73_RS13255	COG0242	peptide deformylase activity
H1I73_RS13260	COG0477	Major facilitator Superfamily
H1I73_RS13270	COG0028	Belongs to the TPP enzyme family
H1I73_RS13285	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13290	COG2267	carboxylic ester hydrolase activity
H1I73_RS13300	COG2271	Major facilitator Superfamily
H1I73_RS13305	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I73_RS13315	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS13335	COG1414	Transcriptional regulator
H1I73_RS13350	COG1024	Enoyl-CoA hydratase
H1I73_RS13360	COG1215	transferase activity, transferring glycosyl groups
H1I73_RS13365	COG0726	polysaccharide deacetylase
H1I73_RS13365	COG1649	PFAM Uncharacterised BCR, COG1649
H1I73_RS13375	COG4681	YaeQ
H1I73_RS13385	COG0523	cobalamin synthesis protein
H1I73_RS13395	COG1607	acyl-coa hydrolase
H1I73_RS13405	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS13410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I73_RS13415	COG1309	transcriptional regulator
H1I73_RS13440	COG2040	homocysteine
H1I73_RS13445	COG0531	amino acid
H1I73_RS13500	COG1595	DNA-templated transcription, initiation
H1I73_RS13510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS13515	COG0477	Major facilitator Superfamily
H1I73_RS13535	COG0084	hydrolase, TatD family'
H1I73_RS13570	COG0629	single-stranded DNA binding
H1I73_RS13625	COG0582	viral genome integration into host DNA
H1I73_RS13730	COG0592	DNA-directed DNA polymerase activity
H1I73_RS13770	COG2026	Addiction module toxin, RelE StbE family
H1I73_RS13920	COG3755	Protein conserved in bacteria
H1I73_RS13965	COG1484	DNA-dependent DNA replication
H1I73_RS14055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I73_RS14125	COG0405	Gamma-glutamyltransferase
H1I73_RS14130	COG2814	Major facilitator Superfamily
H1I73_RS14140	COG2050	protein possibly involved in aromatic compounds catabolism
H1I73_RS14155	COG1090	epimerase
H1I73_RS14175	COG0420	3'-5' exonuclease activity
H1I73_RS14200	COG0735	belongs to the Fur family
H1I73_RS14205	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I73_RS14225	COG0121	glutamine amidotransferase
H1I73_RS14240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I73_RS14250	COG0210	DNA helicase
H1I73_RS14255	COG2885	chlorophyll binding
H1I73_RS14260	COG0204	Acyl-transferase
H1I73_RS14275	COG2894	cell division
H1I73_RS14295	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS14300	COG1674	ftsk spoiiie
H1I73_RS14300	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I73_RS14305	COG0492	ferredoxin-NADP+ reductase activity
H1I73_RS14310	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I73_RS14320	COG0456	acetyltransferase
H1I73_RS14365	COG1981	membrane
H1I73_RS14380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I73_RS14380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I73_RS14400	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS14410	COG0657	acetylesterase activity
H1I73_RS14420	COG0473	3-isopropylmalate dehydrogenase activity
H1I73_RS14445	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I73_RS14470	COG0564	pseudouridine synthase activity
H1I73_RS14480	COG0358	DNA primase activity
H1I73_RS14495	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I73_RS14525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I73_RS14555	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I73_RS14565	COG0351	phosphomethylpyrimidine kinase
H1I73_RS14565	COG0352	thiamine-phosphate diphosphorylase activity
H1I73_RS14570	COG1652	LysM domain
H1I73_RS14595	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I73_RS14600	COG3101	peptidyl-lysine hydroxylation
H1I73_RS14605	COG0009	L-threonylcarbamoyladenylate synthase
H1I73_RS14610	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I73_RS14615	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I73_RS14630	COG4106	trans-aconitate 2-methyltransferase activity
H1I73_RS14645	COG0596	Alpha beta hydrolase
H1I73_RS14645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS14645	COG2226	methyltransferase
H1I73_RS14650	COG1877	trehalose-phosphatase activity
H1I73_RS14655	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I73_RS14660	COG2223	nitrite transmembrane transporter activity
H1I73_RS14680	COG1196	nuclear chromosome segregation
H1I73_RS14690	COG0730	response to heat
H1I73_RS14705	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I73_RS14715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I73_RS14765	COG0489	protein tyrosine kinase activity
H1I73_RS14775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS14775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS14805	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I73_RS14810	COG2081	HI0933 family
H1I73_RS14820	COG0668	transmembrane transport
H1I73_RS14840	COG0583	DNA-binding transcription factor activity
H1I73_RS14860	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I73_RS14865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I73_RS14895	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I73_RS14935	COG0745	RESPONSE REGULATOR receiver
H1I73_RS14955	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I73_RS14965	COG2205	protein histidine kinase activity
H1I73_RS15035	COG4993	Dehydrogenase
H1I73_RS15060	COG0384	phenazine biosynthesis protein PhzF
H1I73_RS15085	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I73_RS15100	COG0583	DNA-binding transcription factor activity
H1I73_RS15130	COG0583	DNA-binding transcription factor activity
H1I73_RS15145	COG0583	DNA-binding transcription factor activity
H1I73_RS15150	COG1053	succinate dehydrogenase
H1I73_RS15160	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I73_RS15165	COG2814	Major facilitator Superfamily
H1I73_RS15170	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS15175	COG0583	DNA-binding transcription factor activity
H1I73_RS15180	COG1063	alcohol dehydrogenase
H1I73_RS15210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I73_RS15215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I73_RS15220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I73_RS15235	COG3667	copper resistance
H1I73_RS15240	COG2132	Multicopper oxidase
H1I73_RS15250	COG0561	phosphatase activity
H1I73_RS15255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I73_RS15280	COG1214	PFAM Peptidase M22, glycoprotease
H1I73_RS15335	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I73_RS15345	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I73_RS15350	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I73_RS15355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I73_RS15415	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I73_RS15425	COG1846	Transcriptional regulator
H1I73_RS15430	COG1764	response to oxidative stress
H1I73_RS15480	COG0037	tRNA processing
H1I73_RS15490	COG0248	Ppx GppA phosphatase
H1I73_RS15520	COG0072	phenylalanine-tRNA ligase activity
H1I73_RS15565	COG1238	metal cluster binding
H1I73_RS15570	COG0625	glutathione transferase activity
H1I73_RS15585	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS15590	COG3028	Belongs to the UPF0307 family
H1I73_RS15595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I73_RS15615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I73_RS15620	COG0617	tRNA 3'-terminal CCA addition
H1I73_RS15625	COG1555	photosystem II stabilization
H1I73_RS15630	COG3956	TIGRFAM MazG family protein
H1I73_RS15640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I73_RS15660	COG0784	Response regulator, receiver
H1I73_RS15660	COG5002	protein histidine kinase activity
H1I73_RS15660	COG2205	protein histidine kinase activity
H1I73_RS15665	COG1024	Enoyl-CoA hydratase
H1I73_RS15670	COG2084	Dehydrogenase
H1I73_RS15675	COG3622	Belongs to the hyi family
H1I73_RS15705	COG0697	spore germination
H1I73_RS15715	COG2814	Major facilitator Superfamily
H1I73_RS15720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I73_RS15730	COG0583	DNA-binding transcription factor activity
H1I73_RS15740	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I73_RS15755	COG0084	hydrolase, TatD family'
H1I73_RS15770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I73_RS15800	COG0440	acetolactate synthase activity
H1I73_RS15805	COG0028	Belongs to the TPP enzyme family
H1I73_RS15830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I73_RS15835	COG1136	(ABC) transporter
H1I73_RS15835	COG0577	efflux transmembrane transporter activity
H1I73_RS15840	COG1538	Outer membrane efflux protein
H1I73_RS15855	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I73_RS15860	COG1162	GTPase activity
H1I73_RS15870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I73_RS15890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I73_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS15935	COG2986	histidine ammonia-lyase
H1I73_RS15950	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS15960	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I73_RS16005	COG1426	Protein conserved in bacteria
H1I73_RS16040	COG0793	Belongs to the peptidase S41A family
H1I73_RS16055	COG2267	carboxylic ester hydrolase activity
H1I73_RS16065	COG1012	belongs to the aldehyde dehydrogenase family
H1I73_RS16070	COG3265	gluconokinase activity
H1I73_RS16080	COG0800	Aldolase
H1I73_RS16095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I73_RS16100	COG0857	belongs to the CobB CobQ family
H1I73_RS16100	COG0280	phosphate acetyltransferase
H1I73_RS16105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I73_RS16105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I73_RS16125	COG0740	serine-type endopeptidase activity
H1I73_RS16135	COG4774	siderophore transport
H1I73_RS16145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I73_RS16155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I73_RS16155	COG2813	Specifically methylates the guanine in position
H1I73_RS16255	COG0788	formyltetrahydrofolate deformylase activity
H1I73_RS16280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS16280	COG4651	solute:proton antiporter activity
H1I73_RS16300	COG0724	RNA recognition motif
H1I73_RS16305	COG0210	DNA helicase
H1I73_RS16330	COG1733	regulation of RNA biosynthetic process
H1I73_RS16340	COG2900	Belongs to the SlyX family
H1I73_RS16345	COG0488	(ABC) transporter
H1I73_RS16350	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS16355	COG1560	Kdo2-lipid A biosynthetic process
H1I73_RS16365	COG1301	dicarboxylic acid transport
H1I73_RS16420	COG0473	3-isopropylmalate dehydrogenase activity
H1I73_RS16485	COG0583	DNA-binding transcription factor activity
H1I73_RS16495	COG0625	glutathione transferase activity
H1I73_RS16500	COG2378	regulation of single-species biofilm formation
H1I73_RS16505	COG0546	phosphoglycolate phosphatase activity
H1I73_RS16515	COG1530	ribonuclease E activity
H1I73_RS16520	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS16535	COG0583	DNA-binding transcription factor activity
H1I73_RS16540	COG4221	oxidoreductase activity
H1I73_RS16545	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I73_RS16555	COG0534	Mate efflux family protein
H1I73_RS16570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I73_RS16610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I73_RS16615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I73_RS16630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I73_RS16640	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I73_RS16640	COG0644	oxidoreductase
H1I73_RS16645	COG0425	Belongs to the sulfur carrier protein TusA family
H1I73_RS16650	COG4535	Mg2 and Co2 transporter CorC
H1I73_RS16660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I73_RS16680	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I73_RS16685	COG0475	glutathione-regulated potassium exporter activity
H1I73_RS16685	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I73_RS16690	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I73_RS16700	COG0484	heat shock protein binding
H1I73_RS16705	COG0789	Transcriptional regulator
H1I73_RS16710	COG0598	Magnesium transport protein CorA
H1I73_RS16725	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I73_RS16730	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I73_RS16735	COG1074	ATP-dependent DNA helicase activity
H1I73_RS16740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I73_RS16760	COG2226	methyltransferase
H1I73_RS16775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I73_RS16780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I73_RS16795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I73_RS16795	COG2111	Na H antiporter
H1I73_RS16800	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I73_RS16805	COG0651	ATP synthesis coupled electron transport
H1I73_RS16810	COG1863	multisubunit Na H antiporter MnhE subunit
H1I73_RS16815	COG2212	antiporter activity
H1I73_RS16820	COG1320	monovalent cation:proton antiporter activity
H1I73_RS16835	COG0195	Participates in both transcription termination and antitermination
H1I73_RS16890	COG0237	dephospho-CoA kinase activity
H1I73_RS16900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I73_RS16915	COG0497	DNA recombination
H1I73_RS16925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I73_RS16955	COG2169	Transcriptional regulator
H1I73_RS16955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I73_RS16960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I73_RS17025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I73_RS17040	COG0326	Molecular chaperone. Has ATPase activity
H1I73_RS17055	COG2056	Na+-H+ antiporter family
H1I73_RS17060	COG0596	Alpha beta hydrolase
H1I73_RS17155	COG0546	phosphoglycolate phosphatase activity
H1I73_RS17160	COG1716	ATPase activity
H1I73_RS17205	COG0181	hydroxymethylbilane synthase activity
H1I73_RS17215	COG3275	phosphorelay sensor kinase activity
H1I73_RS17235	COG1538	Outer membrane efflux protein
H1I73_RS17240	COG0697	spore germination
H1I73_RS17265	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I73_RS17270	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I73_RS17275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I73_RS17280	COG0772	Belongs to the SEDS family
H1I73_RS17305	COG4974	Belongs to the 'phage' integrase family
H1I73_RS17310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS17320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I73_RS17330	COG2197	response regulator
H1I73_RS17345	COG0793	Belongs to the peptidase S41A family
H1I73_RS17350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I73_RS17355	COG0795	lipopolysaccharide-transporting ATPase activity
H1I73_RS17395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I73_RS17395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I73_RS17405	COG0004	ammonium transporteR
H1I73_RS17410	COG0347	Belongs to the P(II) protein family
H1I73_RS17485	COG1061	Type III restriction enzyme res subunit
H1I73_RS17490	COG1002	Type II restriction enzyme, methylase subunits
H1I73_RS17500	COG0659	secondary active sulfate transmembrane transporter activity
H1I73_RS17505	COG0589	response to stress
H1I73_RS17550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I73_RS17570	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I73_RS17585	COG0318	PFAM AMP-dependent synthetase and ligase
H1I73_RS17595	COG0477	Major facilitator Superfamily
H1I73_RS17600	COG2860	membrane
H1I73_RS17610	COG1253	flavin adenine dinucleotide binding
H1I73_RS17630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I73_RS17670	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I73_RS17680	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I73_RS17750	COG0758	DNA mediated transformation
H1I73_RS17760	COG0697	spore germination
H1I73_RS17765	COG1309	transcriptional regulator
H1I73_RS17780	COG0386	Belongs to the glutathione peroxidase family
H1I73_RS17845	COG1121	(ABC) transporter
H1I73_RS17850	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I73_RS17855	COG1280	lysine exporter protein (LysE YggA)
H1I73_RS17860	COG2837	iron assimilation
H1I73_RS17870	COG0281	malic enzyme
H1I73_RS17915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I73_RS17915	COG0519	Catalyzes the synthesis of GMP from XMP
H1I73_RS17920	COG4399	Belongs to the UPF0754 family
H1I73_RS17925	COG2259	Doxx family
H1I73_RS17945	COG1192	Involved in chromosome partitioning
H1I73_RS17955	COG0271	Belongs to the BolA IbaG family
H1I73_RS17975	COG2267	carboxylic ester hydrolase activity
H1I73_RS17995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I73_RS17995	COG3321	synthase
H1I73_RS17995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I73_RS17995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I73_RS18000	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS18010	COG2197	response regulator
H1I73_RS18020	COG3916	Acyl-homoserine-lactone synthase
H1I73_RS18025	COG0477	Major facilitator Superfamily
H1I73_RS18030	COG1024	Enoyl-CoA hydratase
H1I73_RS18035	COG1024	Enoyl-CoA hydratase
H1I73_RS18040	COG1960	acyl-CoA dehydrogenase activity
H1I73_RS18045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I73_RS18065	COG1113	amino acid transport
H1I73_RS18070	COG1113	amino acid transport
H1I73_RS18075	COG0251	oxidation-reduction process
H1I73_RS18115	COG0564	pseudouridine synthase activity
H1I73_RS18175	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I73_RS18190	COG1802	Transcriptional regulator
H1I73_RS18200	COG1448	Aminotransferase
H1I73_RS18205	COG0277	FAD linked oxidase domain protein
H1I73_RS18215	COG2186	Transcriptional regulator
H1I73_RS18225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I73_RS18230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I73_RS18245	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I73_RS18250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I73_RS18275	COG0438	transferase activity, transferring glycosyl groups
H1I73_RS18305	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I73_RS18335	COG0728	peptidoglycan biosynthetic process
H1I73_RS18340	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I73_RS18395	COG0546	phosphoglycolate phosphatase activity
H1I73_RS18400	COG1028	Short-chain dehydrogenase reductase Sdr
H1I73_RS18420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS18425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I73_RS18430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I73_RS18435	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I73_RS18440	COG1116	anion transmembrane transporter activity
H1I73_RS18445	COG1309	transcriptional regulator
H1I73_RS18450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I73_RS18460	COG0196	riboflavin kinase activity
H1I73_RS18465	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I73_RS18475	COG1047	Peptidyl-prolyl cis-trans
H1I73_RS18515	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I73_RS18520	COG0657	acetylesterase activity
H1I73_RS18570	COG2951	lytic endotransglycosylase activity
H1I73_RS18575	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I73_RS18590	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I73_RS18600	COG0671	phosphoesterase, PA-phosphatase related
H1I73_RS18605	COG0861	Integral membrane protein TerC family
H1I73_RS18615	COG0754	glutathionylspermidine amidase activity
H1I73_RS18625	COG0402	S-adenosylhomocysteine deaminase activity
H1I73_RS18640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS18645	COG1230	cation diffusion facilitator family transporter
H1I73_RS18660	COG0706	membrane insertase activity
H1I73_RS18680	COG1192	Involved in chromosome partitioning
H1I73_RS18750	COG1061	Type III restriction enzyme res subunit
H1I73_RS18760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I73_RS18765	COG1192	Involved in chromosome partitioning
H1I73_RS18830	COG0484	heat shock protein binding
H1I73_RS18960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I73_RS19080	COG1525	nuclease