locus-tag	class	description
H1I71_RS00010	COG0592	DNA-directed DNA polymerase activity
H1I71_RS00020	COG0187	DNA topoisomerase II activity
H1I71_RS00030	COG0586	Pfam SNARE associated Golgi protein
H1I71_RS00035	COG0488	(ABC) transporter
H1I71_RS00060	COG0596	Alpha beta hydrolase
H1I71_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I71_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I71_RS00110	COG0733	neurotransmitter:sodium symporter activity
H1I71_RS00150	COG2233	PERMEase
H1I71_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS00200	COG2814	Major facilitator Superfamily
H1I71_RS00205	COG0656	L-ascorbic acid biosynthetic process
H1I71_RS00210	COG0583	DNA-binding transcription factor activity
H1I71_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_RS00230	COG1064	alcohol dehydrogenase
H1I71_RS00235	COG2818	Glycosylase
H1I71_RS00250	COG1194	a g-specific adenine glycosylase
H1I71_RS00270	COG2983	Belongs to the UPF0260 family
H1I71_RS00275	COG2133	pyrroloquinoline quinone binding
H1I71_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I71_RS00285	COG2116	formate transmembrane transporter activity
H1I71_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_RS00310	COG1335	isochorismatase
H1I71_RS00315	COG0385	Bile acid
H1I71_RS00320	COG0534	Mate efflux family protein
H1I71_RS00325	COG1683	Conserved Protein
H1I71_RS00345	COG0625	glutathione transferase activity
H1I71_RS00355	COG1113	amino acid transport
H1I71_RS00365	COG0523	cobalamin synthesis protein
H1I71_RS00375	COG2188	Transcriptional regulator
H1I71_RS00405	COG0010	Belongs to the arginase family
H1I71_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I71_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I71_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I71_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I71_RS00540	COG0534	Mate efflux family protein
H1I71_RS00545	COG0436	Aminotransferase
H1I71_RS00550	COG2733	membrane
H1I71_RS00565	COG2918	glutathione biosynthetic process
H1I71_RS00580	COG1388	LysM domain
H1I71_RS00580	COG0791	NLP P60 protein
H1I71_RS00595	COG3150	esterase
H1I71_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I71_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_RS00630	COG2233	PERMEase
H1I71_RS00635	COG2351	hydroxyisourate hydrolase activity
H1I71_RS00670	COG3706	GGDEF domain
H1I71_RS00685	COG1393	Belongs to the ArsC family
H1I71_RS00690	COG0708	Exodeoxyribonuclease III
H1I71_RS00710	COG0189	ligase activity
H1I71_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I71_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I71_RS00755	COG4942	peptidase
H1I71_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I71_RS00775	COG2119	membrane
H1I71_RS00780	COG4774	siderophore transport
H1I71_RS00785	COG0426	domain, Protein
H1I71_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I71_RS00830	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS00835	COG1519	Transferase
H1I71_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I71_RS00845	COG0668	transmembrane transport
H1I71_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_RS00860	COG1335	isochorismatase
H1I71_RS00865	COG1522	sequence-specific DNA binding
H1I71_RS00870	COG3328	transposase activity
H1I71_RS00900	COG0784	Response regulator, receiver
H1I71_RS00900	COG2205	protein histidine kinase activity
H1I71_RS00900	COG2198	Histidine kinase
H1I71_RS00905	COG3162	membrane
H1I71_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I71_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I71_RS00945	COG1309	transcriptional regulator
H1I71_RS00965	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_RS00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I71_RS00965	COG0351	phosphomethylpyrimidine kinase
H1I71_RS00975	COG2814	Major facilitator Superfamily
H1I71_RS00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I71_RS01000	COG1113	amino acid transport
H1I71_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I71_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS01025	COG1335	isochorismatase
H1I71_RS01055	COG2814	Major facilitator Superfamily
H1I71_RS01060	COG0583	DNA-binding transcription factor activity
H1I71_RS01080	COG0667	Aldo Keto reductase
H1I71_RS01115	COG1733	regulation of RNA biosynthetic process
H1I71_RS01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_RS01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I71_RS01200	COG2329	Antibiotic biosynthesis monooxygenase
H1I71_RS01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I71_RS01260	COG0427	acetyl-CoA hydrolase
H1I71_RS01285	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_RS01290	COG4221	oxidoreductase activity
H1I71_RS01295	COG2873	o-acetylhomoserine
H1I71_RS01300	COG0488	(ABC) transporter
H1I71_RS01385	COG0833	amino acid
H1I71_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I71_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I71_RS01450	COG2226	methyltransferase
H1I71_RS01500	COG0069	glutamate synthase activity
H1I71_RS01500	COG0070	glutamate synthase
H1I71_RS01500	COG0067	glutamate synthase
H1I71_RS01505	COG0493	'glutamate synthase
H1I71_RS01515	COG1704	LemA family
H1I71_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I71_RS01540	COG3307	-O-antigen
H1I71_RS01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I71_RS01580	COG0194	GDP metabolic process
H1I71_RS01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I71_RS01650	COG5380	lipid catabolic process
H1I71_RS01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I71_RS01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I71_RS01685	COG0277	FAD linked oxidase domain protein
H1I71_RS01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I71_RS01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_RS01715	COG1289	transmembrane transporter activity
H1I71_RS01725	COG0628	permease
H1I71_RS01730	COG1192	Involved in chromosome partitioning
H1I71_RS01760	COG0833	amino acid
H1I71_RS01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I71_RS01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I71_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS01820	COG0583	DNA-binding transcription factor activity
H1I71_RS01865	COG0517	IMP dehydrogenase activity
H1I71_RS01870	COG1983	PspC domain protein
H1I71_RS01880	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS01895	COG0408	coproporphyrinogen oxidase activity
H1I71_RS01915	COG0513	Belongs to the DEAD box helicase family
H1I71_RS01925	COG1127	ABC transporter
H1I71_RS01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I71_RS01940	COG2854	intermembrane phospholipid transfer
H1I71_RS01950	COG0598	Magnesium transport protein CorA
H1I71_RS01960	COG0494	nUDIX hydrolase
H1I71_RS01965	COG1040	competence protein
H1I71_RS01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I71_RS01990	COG1946	Acyl-CoA thioesterase
H1I71_RS01995	COG1301	dicarboxylic acid transport
H1I71_RS02010	COG1959	2 iron, 2 sulfur cluster binding
H1I71_RS02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_RS02015	COG1017	nitric oxide dioxygenase activity
H1I71_RS02020	COG0433	COG0433 Predicted ATPase
H1I71_RS02025	COG0626	cystathionine gamma-synthase activity
H1I71_RS02180	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I71_RS02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I71_RS02220	COG0339	signal peptide processing
H1I71_RS02225	COG0557	exoribonuclease II activity
H1I71_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I71_RS02270	COG2169	Transcriptional regulator
H1I71_RS02275	COG0697	spore germination
H1I71_RS02280	COG1295	ribonuclease BN
H1I71_RS02315	COG1702	phosphate starvation-inducible protein PhoH
H1I71_RS02325	COG0739	heme binding
H1I71_RS02325	COG0741	lytic transglycosylase activity
H1I71_RS02325	COG1196	nuclear chromosome segregation
H1I71_RS02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I71_RS02360	COG1183	phosphatidylcholine synthase activity
H1I71_RS02405	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS02410	COG1309	transcriptional regulator
H1I71_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I71_RS02430	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS02450	COG2969	positive regulation of protein catabolic process
H1I71_RS02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I71_RS02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I71_RS02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I71_RS02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I71_RS02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I71_RS02515	COG1408	metallophosphoesterase
H1I71_RS02525	COG2199	diguanylate cyclase activity
H1I71_RS02585	COG1607	acyl-coa hydrolase
H1I71_RS02615	COG2350	Protein conserved in bacteria
H1I71_RS02625	COG0613	PHP domain protein
H1I71_RS02630	COG3781	membrane
H1I71_RS02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I71_RS02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I71_RS02655	COG1862	Preprotein translocase
H1I71_RS02685	COG2205	protein histidine kinase activity
H1I71_RS02690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I71_RS02710	COG0726	polysaccharide deacetylase
H1I71_RS02715	COG0463	Glycosyl transferase, family 2
H1I71_RS02720	COG0438	transferase activity, transferring glycosyl groups
H1I71_RS02785	COG0625	glutathione transferase activity
H1I71_RS02790	COG0583	DNA-binding transcription factor activity
H1I71_RS02795	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS02800	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS02810	COG2205	protein histidine kinase activity
H1I71_RS02815	COG0745	RESPONSE REGULATOR receiver
H1I71_RS02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I71_RS02840	COG2096	Adenosyltransferase
H1I71_RS02890	COG0285	dihydrofolate synthase activity
H1I71_RS02910	COG0450	alkyl hydroperoxide reductase
H1I71_RS02925	COG0477	Major facilitator Superfamily
H1I71_RS02930	COG1272	protein, Hemolysin III
H1I71_RS02960	COG0183	Belongs to the thiolase family
H1I71_RS02965	COG2207	Transcriptional regulator
H1I71_RS02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_RS03005	COG0183	Belongs to the thiolase family
H1I71_RS03015	COG2885	chlorophyll binding
H1I71_RS03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I71_RS03025	COG1690	Belongs to the RtcB family
H1I71_RS03030	COG0833	amino acid
H1I71_RS03040	COG2233	PERMEase
H1I71_RS03045	COG1217	gtp-binding protein TYPA
H1I71_RS03070	COG2094	Belongs to the DNA glycosylase MPG family
H1I71_RS03090	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_RS03110	COG0354	folic acid binding
H1I71_RS03120	COG3189	MarR family transcriptional regulator
H1I71_RS03125	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I71_RS03130	COG3422	double-strand break repair
H1I71_RS03170	COG0840	transmembrane signaling receptor activity
H1I71_RS03190	COG5510	response to toxic substance
H1I71_RS03200	COG2832	Protein of unknown function (DUF454)
H1I71_RS03205	COG1376	ErfK ybiS ycfS ynhG family protein
H1I71_RS03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I71_RS03255	COG1289	transmembrane transporter activity
H1I71_RS03260	COG2814	Major facilitator Superfamily
H1I71_RS03280	COG1115	amino acid carrier protein
H1I71_RS03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I71_RS03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I71_RS03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I71_RS03325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I71_RS03335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I71_RS03340	COG1077	Cell shape determining protein MreB Mrl
H1I71_RS03345	COG1792	Involved in formation and maintenance of cell shape
H1I71_RS03350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I71_RS03355	COG0424	maF-like protein
H1I71_RS03360	COG1530	ribonuclease E activity
H1I71_RS03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_RS03380	COG0560	Phosphoserine phosphatase
H1I71_RS03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_RS03415	COG2207	Transcriptional regulator
H1I71_RS03435	COG1113	amino acid transport
H1I71_RS03440	COG2828	Protein conserved in bacteria
H1I71_RS03445	COG0142	geranyltranstransferase activity
H1I71_RS03450	COG2315	Protein conserved in bacteria
H1I71_RS03465	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I71_RS03485	COG2194	sulfuric ester hydrolase activity
H1I71_RS03490	COG0745	RESPONSE REGULATOR receiver
H1I71_RS03495	COG0642	Histidine kinase
H1I71_RS03505	COG0004	ammonium transporteR
H1I71_RS03510	COG0583	DNA-binding transcription factor activity
H1I71_RS03530	COG0525	valine-tRNA ligase activity
H1I71_RS03540	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS03550	COG0393	Putative heavy-metal-binding
H1I71_RS03555	COG0393	Putative heavy-metal-binding
H1I71_RS03560	COG1538	Outer membrane efflux protein
H1I71_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS03575	COG0671	phosphoesterase, PA-phosphatase related
H1I71_RS03605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I71_RS03620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I71_RS03620	COG1648	precorrin-2 dehydrogenase activity
H1I71_RS03625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I71_RS03630	COG1733	regulation of RNA biosynthetic process
H1I71_RS03640	COG0531	amino acid
H1I71_RS03655	COG0321	lipoyl(octanoyl) transferase activity
H1I71_RS03660	COG2921	Belongs to the UPF0250 family
H1I71_RS03700	COG2009	succinate dehydrogenase
H1I71_RS03705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I71_RS03710	COG1053	succinate dehydrogenase
H1I71_RS03715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I71_RS03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_RS03760	COG2354	Protein conserved in bacteria
H1I71_RS03765	COG2321	neutral zinc metallopeptidase
H1I71_RS03785	COG2843	Capsule synthesis protein
H1I71_RS03800	COG0589	response to stress
H1I71_RS03820	COG0505	Belongs to the CarA family
H1I71_RS03845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I71_RS03850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I71_RS03900	COG0477	Major facilitator Superfamily
H1I71_RS03905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I71_RS03920	COG1597	lipid kinase activity
H1I71_RS03925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I71_RS03955	COG0584	glycerophosphoryl diester phosphodiesterase
H1I71_RS03975	COG0741	lytic transglycosylase activity
H1I71_RS03995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I71_RS04010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_RS04040	COG0778	Nitroreductase
H1I71_RS04055	COG1929	Belongs to the glycerate kinase type-1 family
H1I71_RS04060	COG0243	molybdopterin cofactor binding
H1I71_RS04065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I71_RS04070	COG3339	Conserved Protein
H1I71_RS04080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I71_RS04095	COG1113	amino acid transport
H1I71_RS04105	COG0019	diaminopimelate decarboxylase activity
H1I71_RS04115	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I71_RS04150	COG0463	Glycosyl transferase, family 2
H1I71_RS04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS04205	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I71_RS04210	COG1136	(ABC) transporter
H1I71_RS04215	COG2333	competence protein COMEC
H1I71_RS04215	COG0658	competence protein
H1I71_RS04225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I71_RS04225	COG0616	signal peptide processing
H1I71_RS04230	COG0596	Alpha beta hydrolase
H1I71_RS04235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I71_RS04245	COG0628	permease
H1I71_RS04280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I71_RS04300	COG0823	Involved in the tonB-independent uptake of proteins
H1I71_RS04320	COG0824	Thioesterase
H1I71_RS04325	COG1473	amidohydrolase
H1I71_RS04345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I71_RS04345	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I71_RS04350	COG2814	Major facilitator Superfamily
H1I71_RS04360	COG1024	Enoyl-CoA hydratase
H1I71_RS04365	COG1051	belongs to the nudix hydrolase family
H1I71_RS04365	COG1056	cytidyltransferase-related domain
H1I71_RS04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I71_RS04390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I71_RS04405	COG4625	pathogenesis
H1I71_RS04410	COG0583	DNA-binding transcription factor activity
H1I71_RS04415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I71_RS04420	COG4208	sulfate ABC transporter
H1I71_RS04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I71_RS04435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I71_RS04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I71_RS04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I71_RS04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I71_RS04480	COG0681	Belongs to the peptidase S26 family
H1I71_RS04495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I71_RS04505	COG1381	Involved in DNA repair and RecF pathway recombination
H1I71_RS04510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I71_RS04520	COG4221	oxidoreductase activity
H1I71_RS04550	COG0436	Aminotransferase
H1I71_RS04570	COG0556	nucleotide-excision repair
H1I71_RS04625	COG2070	2-Nitropropane dioxygenase
H1I71_RS04655	COG1215	transferase activity, transferring glycosyl groups
H1I71_RS04670	COG0415	Belongs to the DNA photolyase family
H1I71_RS04680	COG1252	NADH dehydrogenase
H1I71_RS04685	COG1686	Belongs to the peptidase S11 family
H1I71_RS04700	COG1187	pseudouridine synthase activity
H1I71_RS04725	COG0477	Major facilitator Superfamily
H1I71_RS04730	COG0583	DNA-binding transcription factor activity
H1I71_RS04735	COG1823	symporter activity
H1I71_RS04745	COG0612	Peptidase, M16
H1I71_RS04770	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_RS04805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_RS04820	COG1309	transcriptional regulator
H1I71_RS04830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I71_RS04835	COG0076	glutamate decarboxylase activity
H1I71_RS04845	COG1522	sequence-specific DNA binding
H1I71_RS04850	COG3961	Belongs to the TPP enzyme family
H1I71_RS04855	COG1113	amino acid transport
H1I71_RS04860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I71_RS04865	COG0573	inorganic phosphate transmembrane transporter activity
H1I71_RS04875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I71_RS04880	COG0616	signal peptide processing
H1I71_RS04915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I71_RS04920	COG1686	Belongs to the peptidase S11 family
H1I71_RS04945	COG0583	DNA-binding transcription factor activity
H1I71_RS04950	COG1067	ATP-dependent peptidase activity
H1I71_RS04995	COG1966	Carbon starvation protein
H1I71_RS05000	COG2879	small protein
H1I71_RS05035	COG2508	Transcriptional regulator
H1I71_RS05035	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I71_RS05055	COG1113	amino acid transport
H1I71_RS05060	COG0583	DNA-binding transcription factor activity
H1I71_RS05065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_RS05070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_RS05080	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS05090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_RS05095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I71_RS05095	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I71_RS05130	COG2814	Major facilitator Superfamily
H1I71_RS05135	COG4948	Mandelate Racemase Muconate Lactonizing
H1I71_RS05145	COG1309	transcriptional regulator
H1I71_RS05165	COG1741	Belongs to the pirin family
H1I71_RS05175	COG2964	Protein conserved in bacteria
H1I71_RS05190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_RS05195	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I71_RS05200	COG4605	iron ion homeostasis
H1I71_RS05205	COG4604	ABC transporter, ATP-binding protein
H1I71_RS05210	COG4607	ABC-type enterochelin transport system periplasmic component
H1I71_RS05215	COG4774	siderophore transport
H1I71_RS05225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I71_RS05230	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I71_RS05235	COG1535	isochorismatase
H1I71_RS05235	COG3433	isochorismatase activity
H1I71_RS05250	COG1132	(ABC) transporter
H1I71_RS05255	COG1132	(ABC) transporter
H1I71_RS05260	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I71_RS05270	COG1169	isochorismate synthase
H1I71_RS05285	COG3739	integral membrane protein
H1I71_RS05310	COG0302	gtp cyclohydrolase
H1I71_RS05320	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I71_RS05350	COG0308	aminopeptidase N
H1I71_RS05355	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I71_RS05370	COG0174	glutamine synthetase
H1I71_RS05380	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I71_RS05415	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I71_RS05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I71_RS05425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I71_RS05445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I71_RS05450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I71_RS05455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I71_RS05470	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS05475	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I71_RS05480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_RS05490	COG2223	nitrite transmembrane transporter activity
H1I71_RS05500	COG0024	Methionine aminopeptidase
H1I71_RS05505	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I71_RS05520	COG2207	Transcriptional regulator
H1I71_RS05545	COG2951	lytic endotransglycosylase activity
H1I71_RS05550	COG0772	Belongs to the SEDS family
H1I71_RS05565	COG0842	Transport permease protein
H1I71_RS05570	COG1131	(ABC) transporter
H1I71_RS05615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS05630	COG4215	(ABC) transporter
H1I71_RS05635	COG4160	amino acid transport
H1I71_RS05640	COG4598	ABC transporter
H1I71_RS05650	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I71_RS05655	COG0826	peptidase U32
H1I71_RS05660	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_RS05675	COG1720	tRNA m6t6A37 methyltransferase activity
H1I71_RS05685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I71_RS05700	COG0642	Histidine kinase
H1I71_RS05710	COG0494	nUDIX hydrolase
H1I71_RS05720	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I71_RS05725	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I71_RS05730	COG3139	Protein of unknown function (DUF1315)
H1I71_RS05735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I71_RS05740	COG1301	dicarboxylic acid transport
H1I71_RS05745	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS05750	COG2819	hydrolase of the alpha beta superfamily
H1I71_RS05760	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I71_RS05770	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I71_RS05775	COG1234	tRNA 3'-trailer cleavage
H1I71_RS05805	COG2363	Small membrane protein
H1I71_RS05830	COG0513	Belongs to the DEAD box helicase family
H1I71_RS05840	COG0778	Nitroreductase
H1I71_RS06190	COG1286	toxin biosynthetic process
H1I71_RS06215	COG4783	chaperone-mediated protein folding
H1I71_RS06220	COG1610	YqeY-like protein
H1I71_RS06320	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I71_RS06345	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I71_RS06350	COG0786	glutamate:sodium symporter activity
H1I71_RS06360	COG2186	Transcriptional regulator
H1I71_RS06410	COG0477	Major facilitator Superfamily
H1I71_RS06440	COG2985	domain, Protein
H1I71_RS06450	COG2995	paraquat-inducible protein a
H1I71_RS06455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I71_RS06455	COG3008	intermembrane lipid transfer
H1I71_RS06465	COG1794	racemase activity, acting on amino acids and derivatives
H1I71_RS06560	COG0488	(ABC) transporter
H1I71_RS06565	COG3173	Aminoglycoside phosphotransferase
H1I71_RS06575	COG2433	Pfam Transposase IS66
H1I71_RS06595	COG1309	transcriptional regulator
H1I71_RS06600	COG1741	Belongs to the pirin family
H1I71_RS06615	COG2072	flavoprotein involved in K transport
H1I71_RS06625	COG2252	PERMEase
H1I71_RS06630	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I71_RS06635	COG3038	cytochrome b561
H1I71_RS06645	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I71_RS06655	COG0527	aspartate kinase activity
H1I71_RS06665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I71_RS06675	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I71_RS06690	COG0667	Aldo Keto reductase
H1I71_RS06710	COG1765	OsmC-like protein
H1I71_RS06725	COG0542	response to heat
H1I71_RS06760	COG2885	chlorophyll binding
H1I71_RS06770	COG0625	glutathione transferase activity
H1I71_RS06775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I71_RS06795	COG3634	alkyl hydroperoxide reductase activity
H1I71_RS06805	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I71_RS06815	COG0450	alkyl hydroperoxide reductase
H1I71_RS06820	COG1643	Atp-dependent helicase
H1I71_RS06835	COG2814	Major facilitator Superfamily
H1I71_RS06840	COG3135	benzoate transporter
H1I71_RS06845	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS06850	COG0543	2 iron, 2 sulfur cluster binding
H1I71_RS06850	COG0633	Ferredoxin
H1I71_RS06855	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I71_RS06860	COG4638	Rieske (2fe-2S)
H1I71_RS06870	COG0583	DNA-binding transcription factor activity
H1I71_RS06920	COG1570	exodeoxyribonuclease VII activity
H1I71_RS06950	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS06955	COG1278	Cold shock
H1I71_RS06990	COG2814	Major facilitator Superfamily
H1I71_RS07025	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I71_RS07025	COG0517	IMP dehydrogenase activity
H1I71_RS07030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I71_RS07040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I71_RS07045	COG1137	ATPase activity
H1I71_RS07050	COG1538	Outer membrane efflux protein
H1I71_RS07080	COG4122	O-methyltransferase activity
H1I71_RS07090	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I71_RS07105	COG1522	sequence-specific DNA binding
H1I71_RS07110	COG5006	permease, DMT superfamily
H1I71_RS07120	COG1560	Kdo2-lipid A biosynthetic process
H1I71_RS07135	COG2814	Major facilitator Superfamily
H1I71_RS07155	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I71_RS07205	COG0583	DNA-binding transcription factor activity
H1I71_RS07210	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I71_RS07230	COG4770	biotin carboxylase activity
H1I71_RS07235	COG0038	chloride channel
H1I71_RS07255	COG1309	transcriptional regulator
H1I71_RS07265	COG1063	alcohol dehydrogenase
H1I71_RS07280	COG0439	Biotin carboxylase
H1I71_RS07285	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I71_RS07305	COG0864	Transcriptional regulator
H1I71_RS07315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_RS07320	COG1116	anion transmembrane transporter activity
H1I71_RS07440	COG0590	tRNA wobble adenosine to inosine editing
H1I71_RS07445	COG2807	transmembrane transport
H1I71_RS07460	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I71_RS07480	COG0583	DNA-binding transcription factor activity
H1I71_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS07550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_RS07570	COG2205	protein histidine kinase activity
H1I71_RS07570	COG0784	Response regulator, receiver
H1I71_RS07590	COG0765	amino acid transport
H1I71_RS07595	COG0765	amino acid transport
H1I71_RS07600	COG1126	abc transporter atp-binding protein
H1I71_RS07605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_RS07610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I71_RS07625	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS07635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I71_RS07640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I71_RS07645	COG1045	serine acetyltransferase
H1I71_RS07660	COG0583	DNA-binding transcription factor activity
H1I71_RS07665	COG0625	glutathione transferase activity
H1I71_RS07670	COG0625	glutathione transferase activity
H1I71_RS07675	COG0583	DNA-binding transcription factor activity
H1I71_RS07685	COG1346	cytolysis
H1I71_RS07705	COG2814	Major facilitator Superfamily
H1I71_RS07715	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I71_RS07720	COG3052	prosthetic group binding
H1I71_RS07740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I71_RS07760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_RS07770	COG1294	oxidase, subunit
H1I71_RS07775	COG1271	oxidase subunit
H1I71_RS07795	COG0477	Major facilitator Superfamily
H1I71_RS07805	COG4521	taurine ABC transporter
H1I71_RS07810	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I71_RS07815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_RS07820	COG2175	clavaminate synthase activity
H1I71_RS07830	COG1953	Uracil, thiamine, allantoin
H1I71_RS07840	COG0583	DNA-binding transcription factor activity
H1I71_RS07850	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I71_RS07865	COG0640	Transcriptional regulator
H1I71_RS07870	COG0798	PFAM Bile acid sodium symporter
H1I71_RS07875	COG0583	DNA-binding transcription factor activity
H1I71_RS07890	COG3634	alkyl hydroperoxide reductase activity
H1I71_RS07930	COG0436	Aminotransferase
H1I71_RS07940	COG0386	Belongs to the glutathione peroxidase family
H1I71_RS07980	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I71_RS08005	COG0012	GTP binding
H1I71_RS08010	COG2011	ABC-type metal ion transport system permease component
H1I71_RS08015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I71_RS08025	COG1464	Belongs to the NlpA lipoprotein family
H1I71_RS08055	COG0765	amino acid transport
H1I71_RS08060	COG0765	amino acid transport
H1I71_RS08065	COG1126	abc transporter atp-binding protein
H1I71_RS08080	COG1522	sequence-specific DNA binding
H1I71_RS08095	COG1309	transcriptional regulator
H1I71_RS08115	COG0583	DNA-binding transcription factor activity
H1I71_RS08125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I71_RS08135	COG0697	spore germination
H1I71_RS08160	COG3121	Chaperone
H1I71_RS08165	COG3539	Fimbrial protein
H1I71_RS08190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I71_RS08190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I71_RS08235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I71_RS08245	COG2353	YceI-like domain
H1I71_RS08255	COG3698	Phosphodiester glycosidase
H1I71_RS08270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I71_RS08275	COG0506	proline dehydrogenase activity
H1I71_RS08275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I71_RS08275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I71_RS08285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I71_RS08290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I71_RS08310	COG1132	(ABC) transporter
H1I71_RS08315	COG3122	Protein conserved in bacteria
H1I71_RS08320	COG3619	membrane
H1I71_RS08330	COG0640	Transcriptional regulator
H1I71_RS08340	COG2850	peptidyl-arginine hydroxylation
H1I71_RS08345	COG0424	maF-like protein
H1I71_RS08365	COG0191	fructose-bisphosphate aldolase activity
H1I71_RS08370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I71_RS08385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I71_RS08395	COG1192	Involved in chromosome partitioning
H1I71_RS08400	COG1475	DNA binding
H1I71_RS08405	COG0811	peptide transport
H1I71_RS08415	COG1132	(ABC) transporter
H1I71_RS08420	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I71_RS08440	COG0084	hydrolase, TatD family'
H1I71_RS08505	COG0776	regulation of translation
H1I71_RS08535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I71_RS08540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I71_RS08600	COG0339	signal peptide processing
H1I71_RS08610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I71_RS08645	COG0702	epimerase
H1I71_RS08650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I71_RS08680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I71_RS08710	COG0316	Belongs to the HesB IscA family
H1I71_RS08715	COG0822	iron-sulfur transferase activity
H1I71_RS08740	COG0776	regulation of translation
H1I71_RS08745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I71_RS08750	COG2207	Transcriptional regulator
H1I71_RS08755	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I71_RS08760	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS08765	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS08780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I71_RS08800	COG4264	IucA IucC family
H1I71_RS08805	COG4264	IucA IucC family
H1I71_RS08845	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I71_RS08860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I71_RS08880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I71_RS08885	COG0730	response to heat
H1I71_RS08905	COG4773	Receptor
H1I71_RS08910	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_RS08925	COG1131	(ABC) transporter
H1I71_RS08930	COG0842	Transport permease protein
H1I71_RS08935	COG0842	Transport permease protein
H1I71_RS08990	COG2226	methyltransferase
H1I71_RS09015	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I71_RS09050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I71_RS09060	COG0133	tryptophan synthase activity
H1I71_RS09075	COG3706	GGDEF domain
H1I71_RS09090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I71_RS09095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I71_RS09100	COG0022	dehydrogenase e1 component
H1I71_RS09105	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I71_RS09110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I71_RS09120	COG1063	alcohol dehydrogenase
H1I71_RS09125	COG3781	membrane
H1I71_RS09135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_RS09135	COG3453	Protein conserved in bacteria
H1I71_RS09150	COG0730	response to heat
H1I71_RS09165	COG3708	Transcriptional regulator
H1I71_RS09165	COG2207	Transcriptional regulator
H1I71_RS09170	COG1733	regulation of RNA biosynthetic process
H1I71_RS09175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I71_RS09185	COG2188	Transcriptional regulator
H1I71_RS09200	COG4521	taurine ABC transporter
H1I71_RS09205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_RS09225	COG0477	Major facilitator Superfamily
H1I71_RS09235	COG1027	Aspartate ammonia-lyase
H1I71_RS09250	COG0583	DNA-binding transcription factor activity
H1I71_RS09255	COG0583	DNA-binding transcription factor activity
H1I71_RS09260	COG0183	Belongs to the thiolase family
H1I71_RS09265	COG2031	fatty acid transporter
H1I71_RS09270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_RS09280	COG0583	DNA-binding transcription factor activity
H1I71_RS09290	COG2610	gluconate transmembrane transporter activity
H1I71_RS09295	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS09305	COG2207	Transcriptional regulator
H1I71_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS09345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I71_RS09345	COG0543	2 iron, 2 sulfur cluster binding
H1I71_RS09350	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I71_RS09355	COG4638	Rieske (2fe-2S)
H1I71_RS09365	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I71_RS09370	COG4149	molybdate abc transporter
H1I71_RS09375	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I71_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS09385	COG1535	isochorismatase
H1I71_RS09385	COG3433	isochorismatase activity
H1I71_RS09445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I71_RS09460	COG0753	catalase activity
H1I71_RS09470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I71_RS09500	COG3539	Fimbrial protein
H1I71_RS09520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I71_RS09540	COG2072	flavoprotein involved in K transport
H1I71_RS09550	COG1538	Outer membrane efflux protein
H1I71_RS09555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I71_RS09560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS09565	COG0745	RESPONSE REGULATOR receiver
H1I71_RS09570	COG2205	protein histidine kinase activity
H1I71_RS09585	COG2207	Transcriptional regulator
H1I71_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS09650	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I71_RS09770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I71_RS09790	COG1120	ATPase activity
H1I71_RS09795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I71_RS09805	COG1064	alcohol dehydrogenase
H1I71_RS09820	COG2207	Transcriptional regulator
H1I71_RS09825	COG2084	Dehydrogenase
H1I71_RS09835	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I71_RS09840	COG0583	DNA-binding transcription factor activity
H1I71_RS09850	COG0129	dihydroxy-acid dehydratase activity
H1I71_RS09855	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS09870	COG1566	PFAM secretion protein HlyD family protein
H1I71_RS09905	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I71_RS09935	COG0583	DNA-binding transcription factor activity
H1I71_RS09950	COG2188	Transcriptional regulator
H1I71_RS09980	COG3210	domain, Protein
H1I71_RS09985	COG2831	hemolysin activation secretion protein
H1I71_RS09995	COG1473	amidohydrolase
H1I71_RS10005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_RS10005	COG0475	glutathione-regulated potassium exporter activity
H1I71_RS10015	COG0583	DNA-binding transcription factor activity
H1I71_RS10020	COG1335	isochorismatase
H1I71_RS10030	COG1309	transcriptional regulator
H1I71_RS10060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I71_RS10070	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_RS10070	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS10075	COG1846	Transcriptional regulator
H1I71_RS10095	COG0753	catalase activity
H1I71_RS10110	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS10125	COG3162	membrane
H1I71_RS10135	COG3829	transcription factor binding
H1I71_RS10140	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS10145	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS10165	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS10185	COG2186	Transcriptional regulator
H1I71_RS10195	COG0583	DNA-binding transcription factor activity
H1I71_RS10200	COG4948	Mandelate Racemase Muconate Lactonizing
H1I71_RS10205	COG4829	muconolactone delta-isomerase
H1I71_RS10215	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I71_RS10220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_RS10225	COG0183	Belongs to the thiolase family
H1I71_RS10230	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_RS10240	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS10250	COG3733	amine oxidase
H1I71_RS10260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_RS10270	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS10280	COG4638	Rieske (2fe-2S)
H1I71_RS10300	COG0154	amidase activity
H1I71_RS10310	COG2814	Major facilitator Superfamily
H1I71_RS10335	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS10340	COG0583	DNA-binding transcription factor activity
H1I71_RS10345	COG1414	Transcriptional regulator
H1I71_RS10360	COG2391	methyltransferase activity
H1I71_RS10370	COG4993	Dehydrogenase
H1I71_RS10375	COG3659	wide pore channel activity
H1I71_RS10380	COG3420	alginic acid biosynthetic process
H1I71_RS10385	COG0710	3-dehydroquinate dehydratase activity
H1I71_RS10390	COG3485	protocatechuate 3,4-dioxygenase
H1I71_RS10395	COG3485	protocatechuate 3,4-dioxygenase
H1I71_RS10400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I71_RS10405	COG2271	Major facilitator Superfamily
H1I71_RS10410	COG0596	Alpha beta hydrolase
H1I71_RS10415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I71_RS10420	COG0183	Belongs to the thiolase family
H1I71_RS10425	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I71_RS10430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I71_RS10440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I71_RS10445	COG2323	membrane
H1I71_RS10490	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_RS10490	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS10515	COG0542	response to heat
H1I71_RS10520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I71_RS10550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I71_RS10555	COG0569	domain protein
H1I71_RS10560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I71_RS10575	COG4774	siderophore transport
H1I71_RS10580	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I71_RS10590	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I71_RS10605	COG1294	oxidase, subunit
H1I71_RS10610	COG4890	Cyd operon protein YbgT
H1I71_RS10625	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I71_RS10635	COG0552	protein localization to endoplasmic reticulum
H1I71_RS10660	COG0516	GMP reductase activity
H1I71_RS10660	COG0517	IMP dehydrogenase activity
H1I71_RS10665	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I71_RS10670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I71_RS10680	COG0583	DNA-binding transcription factor activity
H1I71_RS10685	COG0024	Methionine aminopeptidase
H1I71_RS10715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I71_RS10715	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I71_RS10720	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I71_RS10725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I71_RS10725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I71_RS10725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I71_RS10745	COG3300	MHYT domain
H1I71_RS10745	COG5001	Diguanylate cyclase
H1I71_RS10760	COG2135	peptidase activity
H1I71_RS10765	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_RS10785	COG1113	amino acid transport
H1I71_RS10795	COG1522	sequence-specific DNA binding
H1I71_RS10820	COG1011	Hydrolase
H1I71_RS10825	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I71_RS10835	COG2137	regulation of response to DNA damage stimulus
H1I71_RS10850	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_RS10885	COG0575	Belongs to the CDS family
H1I71_RS10890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I71_RS10910	COG3852	Histidine kinase
H1I71_RS10915	COG2204	response regulator
H1I71_RS10980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I71_RS10985	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I71_RS11005	COG0697	spore germination
H1I71_RS11010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_RS11020	COG0303	'Molybdopterin
H1I71_RS11025	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I71_RS11025	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I71_RS11040	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I71_RS11045	COG0243	molybdopterin cofactor binding
H1I71_RS11055	COG0243	molybdopterin cofactor binding
H1I71_RS11060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_RS11065	COG2146	nitrite reductase [NAD(P)H] activity
H1I71_RS11065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_RS11075	COG0745	RESPONSE REGULATOR receiver
H1I71_RS11080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_RS11080	COG1116	anion transmembrane transporter activity
H1I71_RS11100	COG0511	ligase activity, forming carbon-carbon bonds
H1I71_RS11115	COG2814	Major facilitator Superfamily
H1I71_RS11185	COG1196	nuclear chromosome segregation
H1I71_RS11185	COG0741	lytic transglycosylase activity
H1I71_RS11185	COG0739	heme binding
H1I71_RS11325	COG5410	chromosome segregation
H1I71_RS11410	COG4197	protein conserved in bacteria, prophage-related
H1I71_RS11415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_RS11485	COG0069	glutamate synthase activity
H1I71_RS11505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I71_RS11515	COG1454	alcohol dehydrogenase
H1I71_RS11520	COG0824	Thioesterase
H1I71_RS11530	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I71_RS11545	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I71_RS11550	COG2030	dehydratase
H1I71_RS11560	COG0183	Belongs to the thiolase family
H1I71_RS11570	COG0583	DNA-binding transcription factor activity
H1I71_RS11575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I71_RS11585	COG1522	sequence-specific DNA binding
H1I71_RS11590	COG3135	benzoate transporter
H1I71_RS11600	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I71_RS11625	COG0589	response to stress
H1I71_RS11630	COG0488	(ABC) transporter
H1I71_RS11650	COG4773	Receptor
H1I71_RS11685	COG0668	transmembrane transport
H1I71_RS11695	COG1309	transcriptional regulator
H1I71_RS11715	COG1605	Chorismate mutase
H1I71_RS11725	COG4221	oxidoreductase activity
H1I71_RS11735	COG0308	aminopeptidase N
H1I71_RS11755	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I71_RS11765	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I71_RS11770	COG1454	alcohol dehydrogenase
H1I71_RS11790	COG0531	amino acid
H1I71_RS11795	COG4303	Ethanolamine ammonia lyase large subunit
H1I71_RS11800	COG4302	ethanolamine ammonia-lyase activity
H1I71_RS11805	COG0519	Catalyzes the synthesis of GMP from XMP
H1I71_RS11805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I71_RS11810	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I71_RS11820	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I71_RS11835	COG0697	spore germination
H1I71_RS11840	COG1923	regulation of RNA biosynthetic process
H1I71_RS11850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I71_RS11855	COG0802	atpase or kinase
H1I71_RS11875	COG1187	pseudouridine synthase activity
H1I71_RS11890	COG0583	DNA-binding transcription factor activity
H1I71_RS11905	COG2814	Major facilitator Superfamily
H1I71_RS11910	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I71_RS11935	COG0729	surface antigen
H1I71_RS11955	COG0174	glutamine synthetase
H1I71_RS11960	COG0745	RESPONSE REGULATOR receiver
H1I71_RS11965	COG2205	protein histidine kinase activity
H1I71_RS11975	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I71_RS11980	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I71_RS12005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_RS12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_RS12015	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS12030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_RS12035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_RS12055	COG0583	DNA-binding transcription factor activity
H1I71_RS12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I71_RS12080	COG3658	cytochrome
H1I71_RS12085	COG1215	transferase activity, transferring glycosyl groups
H1I71_RS12090	COG0726	polysaccharide deacetylase
H1I71_RS12090	COG1649	PFAM Uncharacterised BCR, COG1649
H1I71_RS12115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I71_RS12120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I71_RS12130	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I71_RS12155	COG0305	Participates in initiation and elongation during chromosome replication
H1I71_RS12160	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I71_RS12170	COG1305	Transglutaminase-like
H1I71_RS12180	COG2308	Evidence 4 Homologs of previously reported genes of
H1I71_RS12210	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I71_RS12215	COG0138	bifunctional purine biosynthesis protein purh
H1I71_RS12220	COG0151	Belongs to the GarS family
H1I71_RS12225	COG1464	Belongs to the NlpA lipoprotein family
H1I71_RS12230	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I71_RS12235	COG2011	ABC-type metal ion transport system permease component
H1I71_RS12240	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_RS12250	COG1301	dicarboxylic acid transport
H1I71_RS12305	COG3209	COG3209 Rhs family protein
H1I71_RS12335	COG4269	membrane
H1I71_RS12350	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_RS12350	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS12360	COG4251	negative regulation of phosphorylation
H1I71_RS12360	COG5001	Diguanylate cyclase
H1I71_RS12360	COG3706	GGDEF domain
H1I71_RS12360	COG2203	Gaf domain
H1I71_RS12370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_RS12390	COG4172	Belongs to the ABC transporter superfamily
H1I71_RS12395	COG4239	(ABC) transporter, permease
H1I71_RS12400	COG4174	ABC transporter (Permease)
H1I71_RS12410	COG0741	lytic transglycosylase activity
H1I71_RS12410	COG1388	LysM domain
H1I71_RS12410	COG0741	lytic transglycosylase activity
H1I71_RS12410	COG1388	LysM domain
H1I71_RS12415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_RS12455	COG0583	DNA-binding transcription factor activity
H1I71_RS12460	COG1279	arginine transmembrane transporter activity
H1I71_RS12480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_RS12485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_RS12490	COG0006	proline dipeptidase activity
H1I71_RS12575	COG1196	nuclear chromosome segregation
H1I71_RS12575	COG0739	heme binding
H1I71_RS12575	COG0741	lytic transglycosylase activity
H1I71_RS12635	COG4695	Portal protein
H1I71_RS12735	COG0305	Participates in initiation and elongation during chromosome replication
H1I71_RS12750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I71_RS12805	COG2194	sulfuric ester hydrolase activity
H1I71_RS12850	COG0739	heme binding
H1I71_RS13175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I71_RS13200	COG3384	dioxygenase
H1I71_RS13210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I71_RS13215	COG2878	Part of a membrane complex involved in electron transport
H1I71_RS13220	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I71_RS13245	COG0768	penicillin binding
H1I71_RS13250	COG0742	ribosomal rna small subunit methyltransferase
H1I71_RS13265	COG0830	nickel cation binding
H1I71_RS13275	COG0804	urea catabolic process
H1I71_RS13315	COG1253	flavin adenine dinucleotide binding
H1I71_RS13320	COG2851	Citrate transporter
H1I71_RS13370	COG1773	rubredoxin
H1I71_RS13375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I71_RS13385	COG0583	DNA-binding transcription factor activity
H1I71_RS13410	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I71_RS13415	COG4181	ATPase activity
H1I71_RS13460	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I71_RS13480	COG0306	phosphate transporter
H1I71_RS13490	COG3958	Transketolase
H1I71_RS13495	COG3959	Transketolase, thiamine diphosphate binding domain
H1I71_RS13500	COG2271	Major facilitator Superfamily
H1I71_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS13510	COG0583	DNA-binding transcription factor activity
H1I71_RS13525	COG2223	nitrite transmembrane transporter activity
H1I71_RS13530	COG2207	Transcriptional regulator
H1I71_RS13535	COG2066	Belongs to the glutaminase family
H1I71_RS13540	COG0242	peptide deformylase activity
H1I71_RS13545	COG0477	Major facilitator Superfamily
H1I71_RS13555	COG0028	Belongs to the TPP enzyme family
H1I71_RS13570	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS13575	COG2267	carboxylic ester hydrolase activity
H1I71_RS13585	COG2271	Major facilitator Superfamily
H1I71_RS13590	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I71_RS13600	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS13620	COG1414	Transcriptional regulator
H1I71_RS13635	COG1024	Enoyl-CoA hydratase
H1I71_RS13645	COG1215	transferase activity, transferring glycosyl groups
H1I71_RS13650	COG0726	polysaccharide deacetylase
H1I71_RS13650	COG1649	PFAM Uncharacterised BCR, COG1649
H1I71_RS13660	COG4681	YaeQ
H1I71_RS13670	COG0523	cobalamin synthesis protein
H1I71_RS13680	COG1607	acyl-coa hydrolase
H1I71_RS13690	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_RS13695	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I71_RS13700	COG1309	transcriptional regulator
H1I71_RS13725	COG2040	homocysteine
H1I71_RS13730	COG0531	amino acid
H1I71_RS13785	COG1595	DNA-templated transcription, initiation
H1I71_RS13795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_RS13800	COG0477	Major facilitator Superfamily
H1I71_RS13820	COG0084	hydrolase, TatD family'
H1I71_RS13855	COG0629	single-stranded DNA binding
H1I71_RS13910	COG0582	viral genome integration into host DNA
H1I71_RS13940	COG1061	Type III restriction enzyme res subunit
H1I71_RS13950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I71_RS13955	COG1192	Involved in chromosome partitioning
H1I71_RS13965	COG1061	Type III restriction enzyme res subunit
H1I71_RS14055	COG0592	DNA-directed DNA polymerase activity
H1I71_RS14095	COG2026	Addiction module toxin, RelE StbE family
H1I71_RS14245	COG3755	Protein conserved in bacteria
H1I71_RS14290	COG1484	DNA-dependent DNA replication
H1I71_RS14380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_RS14450	COG0405	Gamma-glutamyltransferase
H1I71_RS14455	COG2814	Major facilitator Superfamily
H1I71_RS14465	COG2050	protein possibly involved in aromatic compounds catabolism
H1I71_RS14480	COG1090	epimerase
H1I71_RS14500	COG0420	3'-5' exonuclease activity
H1I71_RS14525	COG0735	belongs to the Fur family
H1I71_RS14530	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I71_RS14550	COG0121	glutamine amidotransferase
H1I71_RS14565	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I71_RS14575	COG0210	DNA helicase
H1I71_RS14580	COG2885	chlorophyll binding
H1I71_RS14585	COG0204	Acyl-transferase
H1I71_RS14600	COG2894	cell division
H1I71_RS14625	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS14630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I71_RS14630	COG1674	ftsk spoiiie
H1I71_RS14635	COG0492	ferredoxin-NADP+ reductase activity
H1I71_RS14640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I71_RS14650	COG0456	acetyltransferase
H1I71_RS14695	COG1981	membrane
H1I71_RS14710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I71_RS14710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I71_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS14740	COG0657	acetylesterase activity
H1I71_RS14750	COG0473	3-isopropylmalate dehydrogenase activity
H1I71_RS14755	COG0583	DNA-binding transcription factor activity
H1I71_RS14775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I71_RS14800	COG0564	pseudouridine synthase activity
H1I71_RS14810	COG0358	DNA primase activity
H1I71_RS14825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I71_RS14855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I71_RS14885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I71_RS14895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I71_RS14895	COG0351	phosphomethylpyrimidine kinase
H1I71_RS14895	COG0352	thiamine-phosphate diphosphorylase activity
H1I71_RS14900	COG1652	LysM domain
H1I71_RS14925	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I71_RS14930	COG3101	peptidyl-lysine hydroxylation
H1I71_RS14935	COG0009	L-threonylcarbamoyladenylate synthase
H1I71_RS14940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I71_RS14945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I71_RS14960	COG4106	trans-aconitate 2-methyltransferase activity
H1I71_RS14975	COG0596	Alpha beta hydrolase
H1I71_RS14975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_RS14975	COG2226	methyltransferase
H1I71_RS14980	COG1877	trehalose-phosphatase activity
H1I71_RS14985	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I71_RS14990	COG2223	nitrite transmembrane transporter activity
H1I71_RS15010	COG1196	nuclear chromosome segregation
H1I71_RS15020	COG0730	response to heat
H1I71_RS15035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I71_RS15045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I71_RS15105	COG0489	protein tyrosine kinase activity
H1I71_RS15115	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_RS15115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_RS15145	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I71_RS15150	COG2081	HI0933 family
H1I71_RS15160	COG0668	transmembrane transport
H1I71_RS15180	COG0583	DNA-binding transcription factor activity
H1I71_RS15200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I71_RS15205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I71_RS15235	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I71_RS15275	COG0745	RESPONSE REGULATOR receiver
H1I71_RS15295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I71_RS15305	COG2205	protein histidine kinase activity
H1I71_RS15375	COG4993	Dehydrogenase
H1I71_RS15400	COG0384	phenazine biosynthesis protein PhzF
H1I71_RS15425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I71_RS15440	COG0583	DNA-binding transcription factor activity
H1I71_RS15470	COG0583	DNA-binding transcription factor activity
H1I71_RS15485	COG0583	DNA-binding transcription factor activity
H1I71_RS15490	COG1053	succinate dehydrogenase
H1I71_RS15500	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I71_RS15505	COG2814	Major facilitator Superfamily
H1I71_RS15510	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS15515	COG0583	DNA-binding transcription factor activity
H1I71_RS15520	COG1063	alcohol dehydrogenase
H1I71_RS15550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I71_RS15555	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I71_RS15560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I71_RS15575	COG3667	copper resistance
H1I71_RS15580	COG2132	Multicopper oxidase
H1I71_RS15590	COG0561	phosphatase activity
H1I71_RS15595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I71_RS15620	COG1214	PFAM Peptidase M22, glycoprotease
H1I71_RS15670	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I71_RS15680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I71_RS15685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I71_RS15690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I71_RS15750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I71_RS15760	COG1846	Transcriptional regulator
H1I71_RS15765	COG1764	response to oxidative stress
H1I71_RS15805	COG0037	tRNA processing
H1I71_RS15815	COG0248	Ppx GppA phosphatase
H1I71_RS15845	COG0072	phenylalanine-tRNA ligase activity
H1I71_RS15890	COG1238	metal cluster binding
H1I71_RS15895	COG0625	glutathione transferase activity
H1I71_RS15910	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_RS15915	COG3028	Belongs to the UPF0307 family
H1I71_RS15920	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I71_RS15940	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I71_RS15945	COG0617	tRNA 3'-terminal CCA addition
H1I71_RS15950	COG1555	photosystem II stabilization
H1I71_RS15955	COG3956	TIGRFAM MazG family protein
H1I71_RS15965	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I71_RS15985	COG2205	protein histidine kinase activity
H1I71_RS15985	COG5002	protein histidine kinase activity
H1I71_RS15985	COG0784	Response regulator, receiver
H1I71_RS15990	COG1024	Enoyl-CoA hydratase
H1I71_RS15995	COG2084	Dehydrogenase
H1I71_RS16000	COG3622	Belongs to the hyi family
H1I71_RS16030	COG0697	spore germination
H1I71_RS16040	COG2814	Major facilitator Superfamily
H1I71_RS16045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I71_RS16055	COG0583	DNA-binding transcription factor activity
H1I71_RS16065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I71_RS16080	COG0084	hydrolase, TatD family'
H1I71_RS16095	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I71_RS16125	COG0440	acetolactate synthase activity
H1I71_RS16130	COG0028	Belongs to the TPP enzyme family
H1I71_RS16155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I71_RS16160	COG1136	(ABC) transporter
H1I71_RS16160	COG0577	efflux transmembrane transporter activity
H1I71_RS16165	COG1538	Outer membrane efflux protein
H1I71_RS16180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I71_RS16185	COG1162	GTPase activity
H1I71_RS16195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I71_RS16215	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I71_RS16220	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS16260	COG2986	histidine ammonia-lyase
H1I71_RS16275	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_RS16285	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I71_RS16330	COG1426	Protein conserved in bacteria
H1I71_RS16365	COG0793	Belongs to the peptidase S41A family
H1I71_RS16380	COG2267	carboxylic ester hydrolase activity
H1I71_RS16390	COG1012	belongs to the aldehyde dehydrogenase family
H1I71_RS16395	COG3265	gluconokinase activity
H1I71_RS16405	COG0800	Aldolase
H1I71_RS16415	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I71_RS16420	COG0280	phosphate acetyltransferase
H1I71_RS16420	COG0857	belongs to the CobB CobQ family
H1I71_RS16425	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I71_RS16425	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I71_RS16445	COG0740	serine-type endopeptidase activity
H1I71_RS16455	COG4774	siderophore transport
H1I71_RS16465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I71_RS16475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I71_RS16475	COG2813	Specifically methylates the guanine in position
H1I71_RS16575	COG0788	formyltetrahydrofolate deformylase activity
H1I71_RS16600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_RS16600	COG4651	solute:proton antiporter activity
H1I71_RS16620	COG0724	RNA recognition motif
H1I71_RS16625	COG0210	DNA helicase
H1I71_RS16650	COG1733	regulation of RNA biosynthetic process
H1I71_RS16660	COG2900	Belongs to the SlyX family
H1I71_RS16665	COG0488	(ABC) transporter
H1I71_RS16670	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS16675	COG1560	Kdo2-lipid A biosynthetic process
H1I71_RS16685	COG1301	dicarboxylic acid transport
H1I71_RS16740	COG0473	3-isopropylmalate dehydrogenase activity
H1I71_RS16805	COG0583	DNA-binding transcription factor activity
H1I71_RS16815	COG0625	glutathione transferase activity
H1I71_RS16820	COG2378	regulation of single-species biofilm formation
H1I71_RS16825	COG0546	phosphoglycolate phosphatase activity
H1I71_RS16835	COG1530	ribonuclease E activity
H1I71_RS16840	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_RS16855	COG0583	DNA-binding transcription factor activity
H1I71_RS16860	COG4221	oxidoreductase activity
H1I71_RS16865	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I71_RS16875	COG0534	Mate efflux family protein
H1I71_RS16890	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I71_RS16930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I71_RS16935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I71_RS16950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I71_RS16960	COG0644	oxidoreductase
H1I71_RS16960	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I71_RS16965	COG0425	Belongs to the sulfur carrier protein TusA family
H1I71_RS16970	COG4535	Mg2 and Co2 transporter CorC
H1I71_RS16980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I71_RS17000	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I71_RS17005	COG0475	glutathione-regulated potassium exporter activity
H1I71_RS17005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I71_RS17010	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I71_RS17020	COG0484	heat shock protein binding
H1I71_RS17025	COG0789	Transcriptional regulator
H1I71_RS17030	COG0598	Magnesium transport protein CorA
H1I71_RS17045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I71_RS17050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I71_RS17055	COG1074	ATP-dependent DNA helicase activity
H1I71_RS17060	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I71_RS17080	COG2226	methyltransferase
H1I71_RS17095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I71_RS17100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I71_RS17115	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I71_RS17115	COG2111	Na H antiporter
H1I71_RS17120	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I71_RS17125	COG0651	ATP synthesis coupled electron transport
H1I71_RS17130	COG1863	multisubunit Na H antiporter MnhE subunit
H1I71_RS17135	COG2212	antiporter activity
H1I71_RS17140	COG1320	monovalent cation:proton antiporter activity
H1I71_RS17155	COG0195	Participates in both transcription termination and antitermination
H1I71_RS17205	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H1I71_RS17210	COG0237	dephospho-CoA kinase activity
H1I71_RS17220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I71_RS17235	COG0497	DNA recombination
H1I71_RS17245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I71_RS17275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I71_RS17275	COG2169	Transcriptional regulator
H1I71_RS17280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I71_RS17345	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I71_RS17360	COG0326	Molecular chaperone. Has ATPase activity
H1I71_RS17375	COG2056	Na+-H+ antiporter family
H1I71_RS17380	COG0596	Alpha beta hydrolase
H1I71_RS17475	COG0546	phosphoglycolate phosphatase activity
H1I71_RS17480	COG1716	ATPase activity
H1I71_RS17525	COG0181	hydroxymethylbilane synthase activity
H1I71_RS17535	COG3275	phosphorelay sensor kinase activity
H1I71_RS17555	COG1538	Outer membrane efflux protein
H1I71_RS17560	COG0697	spore germination
H1I71_RS17585	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I71_RS17590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I71_RS17595	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I71_RS17600	COG0772	Belongs to the SEDS family
H1I71_RS17625	COG4974	Belongs to the 'phage' integrase family
H1I71_RS17630	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_RS17640	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I71_RS17650	COG2197	response regulator
H1I71_RS17665	COG0793	Belongs to the peptidase S41A family
H1I71_RS17670	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I71_RS17675	COG0795	lipopolysaccharide-transporting ATPase activity
H1I71_RS17715	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I71_RS17715	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I71_RS17725	COG0004	ammonium transporteR
H1I71_RS17730	COG0347	Belongs to the P(II) protein family
H1I71_RS17790	COG0659	secondary active sulfate transmembrane transporter activity
H1I71_RS17795	COG0589	response to stress
H1I71_RS17830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I71_RS17840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I71_RS17860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I71_RS17875	COG0318	PFAM AMP-dependent synthetase and ligase
H1I71_RS17885	COG0477	Major facilitator Superfamily
H1I71_RS17890	COG2860	membrane
H1I71_RS17900	COG1253	flavin adenine dinucleotide binding
H1I71_RS17920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I71_RS17960	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I71_RS17970	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I71_RS18040	COG0758	DNA mediated transformation
H1I71_RS18050	COG0697	spore germination
H1I71_RS18055	COG1309	transcriptional regulator
H1I71_RS18070	COG0386	Belongs to the glutathione peroxidase family
H1I71_RS18135	COG1121	(ABC) transporter
H1I71_RS18140	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I71_RS18145	COG1280	lysine exporter protein (LysE YggA)
H1I71_RS18150	COG2837	iron assimilation
H1I71_RS18160	COG0281	malic enzyme
H1I71_RS18205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I71_RS18205	COG0519	Catalyzes the synthesis of GMP from XMP
H1I71_RS18210	COG4399	Belongs to the UPF0754 family
H1I71_RS18215	COG2259	Doxx family
H1I71_RS18220	COG0586	Pfam SNARE associated Golgi protein
H1I71_RS18235	COG1192	Involved in chromosome partitioning
H1I71_RS18245	COG0271	Belongs to the BolA IbaG family
H1I71_RS18260	COG2267	carboxylic ester hydrolase activity
H1I71_RS18280	COG3321	synthase
H1I71_RS18280	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I71_RS18280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I71_RS18280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I71_RS18285	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS18295	COG2197	response regulator
H1I71_RS18305	COG3916	Acyl-homoserine-lactone synthase
H1I71_RS18310	COG0477	Major facilitator Superfamily
H1I71_RS18315	COG1024	Enoyl-CoA hydratase
H1I71_RS18320	COG1024	Enoyl-CoA hydratase
H1I71_RS18325	COG1960	acyl-CoA dehydrogenase activity
H1I71_RS18330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I71_RS18350	COG1113	amino acid transport
H1I71_RS18355	COG1113	amino acid transport
H1I71_RS18360	COG0251	oxidation-reduction process
H1I71_RS18400	COG0564	pseudouridine synthase activity
H1I71_RS18460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I71_RS18475	COG1802	Transcriptional regulator
H1I71_RS18485	COG1448	Aminotransferase
H1I71_RS18490	COG0277	FAD linked oxidase domain protein
H1I71_RS18500	COG2186	Transcriptional regulator
H1I71_RS18510	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I71_RS18515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I71_RS18530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I71_RS18535	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I71_RS18540	COG1216	Glycosyl transferase, family 2
H1I71_RS18570	COG2089	acid synthase
H1I71_RS18585	COG1083	cytidylyl-transferase
H1I71_RS18590	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H1I71_RS18595	COG1086	Polysaccharide biosynthesis protein
H1I71_RS18600	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I71_RS18605	COG1596	polysaccharide export
H1I71_RS18630	COG0728	peptidoglycan biosynthetic process
H1I71_RS18635	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I71_RS18695	COG0546	phosphoglycolate phosphatase activity
H1I71_RS18700	COG1028	Short-chain dehydrogenase reductase Sdr
H1I71_RS18720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_RS18725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I71_RS18730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I71_RS18735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I71_RS18740	COG1116	anion transmembrane transporter activity
H1I71_RS18745	COG1309	transcriptional regulator
H1I71_RS18750	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I71_RS18760	COG0196	riboflavin kinase activity
H1I71_RS18765	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I71_RS18775	COG1047	Peptidyl-prolyl cis-trans
H1I71_RS18815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I71_RS18820	COG0657	acetylesterase activity
H1I71_RS18840	COG0583	DNA-binding transcription factor activity
H1I71_RS18870	COG2951	lytic endotransglycosylase activity
H1I71_RS18875	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I71_RS18890	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I71_RS18900	COG0671	phosphoesterase, PA-phosphatase related
H1I71_RS18905	COG0861	Integral membrane protein TerC family
H1I71_RS18915	COG0754	glutathionylspermidine amidase activity
H1I71_RS18925	COG0402	S-adenosylhomocysteine deaminase activity
H1I71_RS18940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_RS18945	COG1230	cation diffusion facilitator family transporter
H1I71_RS18960	COG0706	membrane insertase activity
H1I71_RS19000	COG0358	DNA primase activity
H1I71_RS19055	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I71_RS19100	COG0587	DNA-directed DNA polymerase activity
H1I71_RS19115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1I71_RS19115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1I71_RS19165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H1I71_RS19165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I71_RS19170	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I71_RS19210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I71_RS19255	COG1309	transcriptional regulator
H1I71_RS19265	COG1902	pentaerythritol trinitrate reductase activity
H1I71_RS19275	COG1979	alcohol dehydrogenase
H1I71_RS19290	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H1I71_RS19315	COG1063	alcohol dehydrogenase
H1I71_RS19395	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I71_RS19415	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I71_RS19575	COG1192	Involved in chromosome partitioning
H1I71_RS19650	COG1061	Type III restriction enzyme res subunit
H1I71_RS19660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I71_RS19665	COG1192	Involved in chromosome partitioning
H1I71_RS19730	COG0484	heat shock protein binding
H1I71_RS19860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I71_RS19980	COG1525	nuclease
H1I71_RS20090	COG4683	PFAM Phage derived protein Gp49-like (DUF891)