locus-tag	class	description
H1I76_RS00010	COG0592	DNA-directed DNA polymerase activity
H1I76_RS00020	COG0187	DNA topoisomerase II activity
H1I76_RS00030	COG0586	Pfam SNARE associated Golgi protein
H1I76_RS00035	COG0488	(ABC) transporter
H1I76_RS00060	COG0596	Alpha beta hydrolase
H1I76_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1I76_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1I76_RS00110	COG0733	neurotransmitter:sodium symporter activity
H1I76_RS00150	COG2233	PERMEase
H1I76_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS00200	COG2814	Major facilitator Superfamily
H1I76_RS00205	COG0656	L-ascorbic acid biosynthetic process
H1I76_RS00210	COG0583	DNA-binding transcription factor activity
H1I76_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I76_RS00230	COG1064	alcohol dehydrogenase
H1I76_RS00235	COG2818	Glycosylase
H1I76_RS00250	COG1194	a g-specific adenine glycosylase
H1I76_RS00270	COG2983	Belongs to the UPF0260 family
H1I76_RS00275	COG2133	pyrroloquinoline quinone binding
H1I76_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1I76_RS00285	COG2116	formate transmembrane transporter activity
H1I76_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I76_RS00310	COG1335	isochorismatase
H1I76_RS00315	COG0385	Bile acid
H1I76_RS00320	COG0534	Mate efflux family protein
H1I76_RS00325	COG1683	Conserved Protein
H1I76_RS00345	COG0625	glutathione transferase activity
H1I76_RS00355	COG1113	amino acid transport
H1I76_RS00365	COG0523	cobalamin synthesis protein
H1I76_RS00375	COG2188	Transcriptional regulator
H1I76_RS00405	COG0010	Belongs to the arginase family
H1I76_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I76_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1I76_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1I76_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1I76_RS00540	COG0534	Mate efflux family protein
H1I76_RS00545	COG0436	Aminotransferase
H1I76_RS00550	COG2733	membrane
H1I76_RS00565	COG2918	glutathione biosynthetic process
H1I76_RS00580	COG0791	NLP P60 protein
H1I76_RS00580	COG1388	LysM domain
H1I76_RS00595	COG3150	esterase
H1I76_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1I76_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I76_RS00630	COG2233	PERMEase
H1I76_RS00635	COG2351	hydroxyisourate hydrolase activity
H1I76_RS00670	COG3706	GGDEF domain
H1I76_RS00685	COG1393	Belongs to the ArsC family
H1I76_RS00690	COG0708	Exodeoxyribonuclease III
H1I76_RS00710	COG0189	ligase activity
H1I76_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1I76_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1I76_RS00755	COG4942	peptidase
H1I76_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I76_RS00775	COG2119	membrane
H1I76_RS00780	COG4774	siderophore transport
H1I76_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I76_RS00785	COG0426	domain, Protein
H1I76_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1I76_RS00830	COG1902	pentaerythritol trinitrate reductase activity
H1I76_RS00835	COG1519	Transferase
H1I76_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I76_RS00845	COG0668	transmembrane transport
H1I76_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I76_RS00860	COG1335	isochorismatase
H1I76_RS00865	COG1522	sequence-specific DNA binding
H1I76_RS00870	COG3328	transposase activity
H1I76_RS00895	COG2205	protein histidine kinase activity
H1I76_RS00895	COG0784	Response regulator, receiver
H1I76_RS00895	COG2198	Histidine kinase
H1I76_RS00900	COG3162	membrane
H1I76_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I76_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I76_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1I76_RS00940	COG1309	transcriptional regulator
H1I76_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I76_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
H1I76_RS00960	COG0351	phosphomethylpyrimidine kinase
H1I76_RS00970	COG2814	Major facilitator Superfamily
H1I76_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I76_RS00995	COG1113	amino acid transport
H1I76_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I76_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS01020	COG1335	isochorismatase
H1I76_RS01050	COG2814	Major facilitator Superfamily
H1I76_RS01055	COG0583	DNA-binding transcription factor activity
H1I76_RS01075	COG0667	Aldo Keto reductase
H1I76_RS01110	COG1733	regulation of RNA biosynthetic process
H1I76_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I76_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1I76_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
H1I76_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1I76_RS01255	COG0427	acetyl-CoA hydrolase
H1I76_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
H1I76_RS01285	COG4221	oxidoreductase activity
H1I76_RS01290	COG2873	o-acetylhomoserine
H1I76_RS01295	COG0488	(ABC) transporter
H1I76_RS01380	COG0833	amino acid
H1I76_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1I76_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1I76_RS01445	COG2226	methyltransferase
H1I76_RS01495	COG0070	glutamate synthase
H1I76_RS01495	COG0067	glutamate synthase
H1I76_RS01495	COG0069	glutamate synthase activity
H1I76_RS01500	COG0493	'glutamate synthase
H1I76_RS01510	COG1704	LemA family
H1I76_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1I76_RS01535	COG3307	-O-antigen
H1I76_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I76_RS01570	COG0194	GDP metabolic process
H1I76_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1I76_RS01640	COG5380	lipid catabolic process
H1I76_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1I76_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1I76_RS01675	COG0277	FAD linked oxidase domain protein
H1I76_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1I76_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I76_RS01705	COG1289	transmembrane transporter activity
H1I76_RS01715	COG0628	permease
H1I76_RS01720	COG1192	Involved in chromosome partitioning
H1I76_RS01750	COG0833	amino acid
H1I76_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I76_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I76_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS01810	COG0583	DNA-binding transcription factor activity
H1I76_RS01855	COG0517	IMP dehydrogenase activity
H1I76_RS01860	COG1983	PspC domain protein
H1I76_RS01870	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS01885	COG0408	coproporphyrinogen oxidase activity
H1I76_RS01905	COG0513	Belongs to the DEAD box helicase family
H1I76_RS01915	COG1127	ABC transporter
H1I76_RS01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1I76_RS01930	COG2854	intermembrane phospholipid transfer
H1I76_RS01940	COG0598	Magnesium transport protein CorA
H1I76_RS01950	COG0494	nUDIX hydrolase
H1I76_RS01955	COG1040	competence protein
H1I76_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1I76_RS01980	COG1946	Acyl-CoA thioesterase
H1I76_RS01985	COG1301	dicarboxylic acid transport
H1I76_RS02000	COG1959	2 iron, 2 sulfur cluster binding
H1I76_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I76_RS02005	COG1017	nitric oxide dioxygenase activity
H1I76_RS02010	COG0433	COG0433 Predicted ATPase
H1I76_RS02015	COG0626	cystathionine gamma-synthase activity
H1I76_RS02170	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1I76_RS02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1I76_RS02210	COG0339	signal peptide processing
H1I76_RS02215	COG0557	exoribonuclease II activity
H1I76_RS02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1I76_RS02265	COG2169	Transcriptional regulator
H1I76_RS02270	COG0697	spore germination
H1I76_RS02275	COG1295	ribonuclease BN
H1I76_RS02310	COG1702	phosphate starvation-inducible protein PhoH
H1I76_RS02320	COG0739	heme binding
H1I76_RS02320	COG1196	nuclear chromosome segregation
H1I76_RS02320	COG0741	lytic transglycosylase activity
H1I76_RS02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1I76_RS02355	COG1183	phosphatidylcholine synthase activity
H1I76_RS02400	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS02405	COG1309	transcriptional regulator
H1I76_RS02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I76_RS02425	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS02445	COG2969	positive regulation of protein catabolic process
H1I76_RS02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1I76_RS02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1I76_RS02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1I76_RS02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1I76_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I76_RS02510	COG1408	metallophosphoesterase
H1I76_RS02520	COG2199	diguanylate cyclase activity
H1I76_RS02580	COG1607	acyl-coa hydrolase
H1I76_RS02610	COG2350	Protein conserved in bacteria
H1I76_RS02620	COG0613	PHP domain protein
H1I76_RS02625	COG3781	membrane
H1I76_RS02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1I76_RS02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1I76_RS02650	COG1862	Preprotein translocase
H1I76_RS02680	COG2205	protein histidine kinase activity
H1I76_RS02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1I76_RS02705	COG0726	polysaccharide deacetylase
H1I76_RS02710	COG0463	Glycosyl transferase, family 2
H1I76_RS02715	COG0438	transferase activity, transferring glycosyl groups
H1I76_RS02780	COG0625	glutathione transferase activity
H1I76_RS02785	COG0583	DNA-binding transcription factor activity
H1I76_RS02790	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS02795	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS02805	COG2205	protein histidine kinase activity
H1I76_RS02810	COG0745	RESPONSE REGULATOR receiver
H1I76_RS02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1I76_RS02835	COG2096	Adenosyltransferase
H1I76_RS02885	COG0285	dihydrofolate synthase activity
H1I76_RS02905	COG0450	alkyl hydroperoxide reductase
H1I76_RS02920	COG0477	Major facilitator Superfamily
H1I76_RS02925	COG1272	protein, Hemolysin III
H1I76_RS02955	COG0183	Belongs to the thiolase family
H1I76_RS02960	COG2207	Transcriptional regulator
H1I76_RS02980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I76_RS03000	COG0183	Belongs to the thiolase family
H1I76_RS03010	COG2885	chlorophyll binding
H1I76_RS03010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1I76_RS03020	COG1690	Belongs to the RtcB family
H1I76_RS03025	COG0833	amino acid
H1I76_RS03035	COG2233	PERMEase
H1I76_RS03040	COG1217	gtp-binding protein TYPA
H1I76_RS03065	COG2094	Belongs to the DNA glycosylase MPG family
H1I76_RS03070	COG4772	TonB-dependent receptor
H1I76_RS03085	COG1902	pentaerythritol trinitrate reductase activity
H1I76_RS03090	COG0679	Auxin Efflux Carrier
H1I76_RS03100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I76_RS03105	COG0354	folic acid binding
H1I76_RS03115	COG3189	MarR family transcriptional regulator
H1I76_RS03120	COG2824	Alkylphosphonate utilization operon protein PhnA
H1I76_RS03125	COG3422	double-strand break repair
H1I76_RS03165	COG0840	transmembrane signaling receptor activity
H1I76_RS03185	COG5510	response to toxic substance
H1I76_RS03195	COG2832	Protein of unknown function (DUF454)
H1I76_RS03200	COG1376	ErfK ybiS ycfS ynhG family protein
H1I76_RS03240	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1I76_RS03250	COG1289	transmembrane transporter activity
H1I76_RS03255	COG2814	Major facilitator Superfamily
H1I76_RS03275	COG1115	amino acid carrier protein
H1I76_RS03280	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I76_RS03285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I76_RS03290	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1I76_RS03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I76_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1I76_RS03345	COG1077	Cell shape determining protein MreB Mrl
H1I76_RS03350	COG1792	Involved in formation and maintenance of cell shape
H1I76_RS03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1I76_RS03360	COG0424	maF-like protein
H1I76_RS03365	COG1530	ribonuclease E activity
H1I76_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I76_RS03385	COG0560	Phosphoserine phosphatase
H1I76_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I76_RS03420	COG2207	Transcriptional regulator
H1I76_RS03440	COG1113	amino acid transport
H1I76_RS03445	COG2828	Protein conserved in bacteria
H1I76_RS03450	COG0142	geranyltranstransferase activity
H1I76_RS03455	COG2315	Protein conserved in bacteria
H1I76_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1I76_RS03490	COG2194	sulfuric ester hydrolase activity
H1I76_RS03495	COG0745	RESPONSE REGULATOR receiver
H1I76_RS03500	COG0642	Histidine kinase
H1I76_RS03510	COG0004	ammonium transporteR
H1I76_RS03515	COG0583	DNA-binding transcription factor activity
H1I76_RS03535	COG0525	valine-tRNA ligase activity
H1I76_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS03555	COG0393	Putative heavy-metal-binding
H1I76_RS03560	COG0393	Putative heavy-metal-binding
H1I76_RS03565	COG1538	Outer membrane efflux protein
H1I76_RS03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS03580	COG0671	phosphoesterase, PA-phosphatase related
H1I76_RS03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1I76_RS03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1I76_RS03625	COG1648	precorrin-2 dehydrogenase activity
H1I76_RS03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1I76_RS03635	COG1733	regulation of RNA biosynthetic process
H1I76_RS03645	COG0531	amino acid
H1I76_RS03660	COG0321	lipoyl(octanoyl) transferase activity
H1I76_RS03665	COG2921	Belongs to the UPF0250 family
H1I76_RS03705	COG2009	succinate dehydrogenase
H1I76_RS03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1I76_RS03715	COG1053	succinate dehydrogenase
H1I76_RS03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1I76_RS03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I76_RS03765	COG2354	Protein conserved in bacteria
H1I76_RS03770	COG2321	neutral zinc metallopeptidase
H1I76_RS03805	COG2843	Capsule synthesis protein
H1I76_RS03820	COG0589	response to stress
H1I76_RS03840	COG0505	Belongs to the CarA family
H1I76_RS03865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I76_RS03870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1I76_RS03920	COG0477	Major facilitator Superfamily
H1I76_RS03925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1I76_RS03940	COG1597	lipid kinase activity
H1I76_RS03945	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I76_RS03975	COG0584	glycerophosphoryl diester phosphodiesterase
H1I76_RS03995	COG0741	lytic transglycosylase activity
H1I76_RS04015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1I76_RS04030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I76_RS04055	COG0778	Nitroreductase
H1I76_RS04070	COG1929	Belongs to the glycerate kinase type-1 family
H1I76_RS04075	COG0243	molybdopterin cofactor binding
H1I76_RS04080	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1I76_RS04085	COG3339	Conserved Protein
H1I76_RS04095	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1I76_RS04110	COG1113	amino acid transport
H1I76_RS04120	COG0019	diaminopimelate decarboxylase activity
H1I76_RS04130	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS04135	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1I76_RS04165	COG0463	Glycosyl transferase, family 2
H1I76_RS04185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS04220	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1I76_RS04225	COG1136	(ABC) transporter
H1I76_RS04230	COG2333	competence protein COMEC
H1I76_RS04230	COG0658	competence protein
H1I76_RS04240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1I76_RS04240	COG0616	signal peptide processing
H1I76_RS04245	COG0596	Alpha beta hydrolase
H1I76_RS04250	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1I76_RS04260	COG0628	permease
H1I76_RS04295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I76_RS04315	COG0823	Involved in the tonB-independent uptake of proteins
H1I76_RS04335	COG0824	Thioesterase
H1I76_RS04340	COG1473	amidohydrolase
H1I76_RS04360	COG0047	phosphoribosylformylglycinamidine synthase activity
H1I76_RS04360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1I76_RS04365	COG2814	Major facilitator Superfamily
H1I76_RS04375	COG1024	Enoyl-CoA hydratase
H1I76_RS04380	COG1056	cytidyltransferase-related domain
H1I76_RS04380	COG1051	belongs to the nudix hydrolase family
H1I76_RS04390	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1I76_RS04405	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1I76_RS04420	COG4625	pathogenesis
H1I76_RS04425	COG0583	DNA-binding transcription factor activity
H1I76_RS04430	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1I76_RS04435	COG4208	sulfate ABC transporter
H1I76_RS04440	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1I76_RS04450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1I76_RS04455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1I76_RS04460	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1I76_RS04480	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I76_RS04495	COG0681	Belongs to the peptidase S26 family
H1I76_RS04510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1I76_RS04520	COG1381	Involved in DNA repair and RecF pathway recombination
H1I76_RS04525	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1I76_RS04535	COG4221	oxidoreductase activity
H1I76_RS04565	COG0436	Aminotransferase
H1I76_RS04585	COG0556	nucleotide-excision repair
H1I76_RS04640	COG2070	2-Nitropropane dioxygenase
H1I76_RS04670	COG1215	transferase activity, transferring glycosyl groups
H1I76_RS04685	COG0415	Belongs to the DNA photolyase family
H1I76_RS04695	COG1252	NADH dehydrogenase
H1I76_RS04700	COG1686	Belongs to the peptidase S11 family
H1I76_RS04715	COG1187	pseudouridine synthase activity
H1I76_RS04740	COG0477	Major facilitator Superfamily
H1I76_RS04745	COG0583	DNA-binding transcription factor activity
H1I76_RS04750	COG1823	symporter activity
H1I76_RS04760	COG0612	Peptidase, M16
H1I76_RS04785	COG0352	thiamine-phosphate diphosphorylase activity
H1I76_RS04820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I76_RS04835	COG1309	transcriptional regulator
H1I76_RS04845	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1I76_RS04850	COG0076	glutamate decarboxylase activity
H1I76_RS04860	COG1522	sequence-specific DNA binding
H1I76_RS04865	COG3961	Belongs to the TPP enzyme family
H1I76_RS04870	COG1113	amino acid transport
H1I76_RS04875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1I76_RS04880	COG0573	inorganic phosphate transmembrane transporter activity
H1I76_RS04890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1I76_RS04895	COG0616	signal peptide processing
H1I76_RS04905	COG3328	transposase activity
H1I76_RS04935	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1I76_RS04940	COG1686	Belongs to the peptidase S11 family
H1I76_RS04965	COG0583	DNA-binding transcription factor activity
H1I76_RS04970	COG1067	ATP-dependent peptidase activity
H1I76_RS05015	COG1966	Carbon starvation protein
H1I76_RS05020	COG2879	small protein
H1I76_RS05050	COG2508	Transcriptional regulator
H1I76_RS05050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H1I76_RS05070	COG1113	amino acid transport
H1I76_RS05075	COG0583	DNA-binding transcription factor activity
H1I76_RS05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I76_RS05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I76_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I76_RS05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H1I76_RS05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I76_RS05140	COG2814	Major facilitator Superfamily
H1I76_RS05145	COG4948	Mandelate Racemase Muconate Lactonizing
H1I76_RS05155	COG1309	transcriptional regulator
H1I76_RS05175	COG1741	Belongs to the pirin family
H1I76_RS05185	COG2964	Protein conserved in bacteria
H1I76_RS05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I76_RS05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I76_RS05210	COG4605	iron ion homeostasis
H1I76_RS05215	COG4604	ABC transporter, ATP-binding protein
H1I76_RS05220	COG4607	ABC-type enterochelin transport system periplasmic component
H1I76_RS05225	COG4774	siderophore transport
H1I76_RS05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1I76_RS05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1I76_RS05245	COG3433	isochorismatase activity
H1I76_RS05245	COG1535	isochorismatase
H1I76_RS05260	COG1132	(ABC) transporter
H1I76_RS05265	COG1132	(ABC) transporter
H1I76_RS05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1I76_RS05280	COG1169	isochorismate synthase
H1I76_RS05295	COG3739	integral membrane protein
H1I76_RS05320	COG0302	gtp cyclohydrolase
H1I76_RS05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1I76_RS05360	COG0308	aminopeptidase N
H1I76_RS05365	COG0512	Glutamine amidotransferase of anthranilate synthase
H1I76_RS05380	COG0174	glutamine synthetase
H1I76_RS05390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1I76_RS05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1I76_RS05430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1I76_RS05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1I76_RS05455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1I76_RS05460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1I76_RS05465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1I76_RS05480	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS05485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I76_RS05490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I76_RS05500	COG2223	nitrite transmembrane transporter activity
H1I76_RS05510	COG0024	Methionine aminopeptidase
H1I76_RS05515	COG0052	Belongs to the universal ribosomal protein uS2 family
H1I76_RS05530	COG2207	Transcriptional regulator
H1I76_RS05555	COG2951	lytic endotransglycosylase activity
H1I76_RS05560	COG0772	Belongs to the SEDS family
H1I76_RS05575	COG0842	Transport permease protein
H1I76_RS05580	COG1131	(ABC) transporter
H1I76_RS05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS05640	COG4215	(ABC) transporter
H1I76_RS05645	COG4160	amino acid transport
H1I76_RS05650	COG4598	ABC transporter
H1I76_RS05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I76_RS05665	COG0826	peptidase U32
H1I76_RS05670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I76_RS05685	COG1720	tRNA m6t6A37 methyltransferase activity
H1I76_RS05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1I76_RS05710	COG0642	Histidine kinase
H1I76_RS05720	COG0494	nUDIX hydrolase
H1I76_RS05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1I76_RS05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1I76_RS05740	COG3139	Protein of unknown function (DUF1315)
H1I76_RS05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1I76_RS05750	COG1301	dicarboxylic acid transport
H1I76_RS05755	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS05760	COG2819	hydrolase of the alpha beta superfamily
H1I76_RS05770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1I76_RS05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1I76_RS05785	COG1234	tRNA 3'-trailer cleavage
H1I76_RS05815	COG2363	Small membrane protein
H1I76_RS05835	COG0513	Belongs to the DEAD box helicase family
H1I76_RS05845	COG0778	Nitroreductase
H1I76_RS06035	COG5410	chromosome segregation
H1I76_RS06390	COG5410	chromosome segregation
H1I76_RS06585	COG1286	toxin biosynthetic process
H1I76_RS06610	COG4783	chaperone-mediated protein folding
H1I76_RS06615	COG1610	YqeY-like protein
H1I76_RS06715	COG3111	PFAM Bacterial OB fold (BOF) protein
H1I76_RS06740	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1I76_RS06745	COG0786	glutamate:sodium symporter activity
H1I76_RS06755	COG2186	Transcriptional regulator
H1I76_RS06805	COG0477	Major facilitator Superfamily
H1I76_RS06830	COG2985	domain, Protein
H1I76_RS06840	COG2995	paraquat-inducible protein a
H1I76_RS06845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1I76_RS06845	COG3008	intermembrane lipid transfer
H1I76_RS06865	COG0482	sulfurtransferase activity
H1I76_RS06880	COG0488	(ABC) transporter
H1I76_RS06885	COG3173	Aminoglycoside phosphotransferase
H1I76_RS06895	COG2433	Pfam Transposase IS66
H1I76_RS06940	COG1301	dicarboxylic acid transport
H1I76_RS06950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I76_RS06955	COG2011	ABC-type metal ion transport system permease component
H1I76_RS06960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I76_RS06965	COG1464	Belongs to the NlpA lipoprotein family
H1I76_RS06970	COG0151	Belongs to the GarS family
H1I76_RS06975	COG0138	bifunctional purine biosynthesis protein purh
H1I76_RS06980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1I76_RS07010	COG2308	Evidence 4 Homologs of previously reported genes of
H1I76_RS07020	COG1305	Transglutaminase-like
H1I76_RS07030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1I76_RS07035	COG0305	Participates in initiation and elongation during chromosome replication
H1I76_RS07060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1I76_RS07070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1I76_RS07075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1I76_RS07100	COG1649	PFAM Uncharacterised BCR, COG1649
H1I76_RS07100	COG0726	polysaccharide deacetylase
H1I76_RS07105	COG1215	transferase activity, transferring glycosyl groups
H1I76_RS07110	COG3658	cytochrome
H1I76_RS07120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I76_RS07135	COG0583	DNA-binding transcription factor activity
H1I76_RS07155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I76_RS07160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I76_RS07175	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS07180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I76_RS07185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I76_RS07210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1I76_RS07215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1I76_RS07225	COG2205	protein histidine kinase activity
H1I76_RS07230	COG0745	RESPONSE REGULATOR receiver
H1I76_RS07235	COG0174	glutamine synthetase
H1I76_RS07255	COG0729	surface antigen
H1I76_RS07280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I76_RS07285	COG2814	Major facilitator Superfamily
H1I76_RS07300	COG0583	DNA-binding transcription factor activity
H1I76_RS07315	COG1187	pseudouridine synthase activity
H1I76_RS07335	COG0802	atpase or kinase
H1I76_RS07340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1I76_RS07350	COG1923	regulation of RNA biosynthetic process
H1I76_RS07355	COG0697	spore germination
H1I76_RS07370	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I76_RS07380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I76_RS07385	COG0519	Catalyzes the synthesis of GMP from XMP
H1I76_RS07385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I76_RS07390	COG4302	ethanolamine ammonia-lyase activity
H1I76_RS07395	COG4303	Ethanolamine ammonia lyase large subunit
H1I76_RS07400	COG0531	amino acid
H1I76_RS07420	COG1454	alcohol dehydrogenase
H1I76_RS07425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I76_RS07435	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H1I76_RS07455	COG0308	aminopeptidase N
H1I76_RS07485	COG1605	Chorismate mutase
H1I76_RS07500	COG1309	transcriptional regulator
H1I76_RS07510	COG0668	transmembrane transport
H1I76_RS07545	COG4773	Receptor
H1I76_RS07565	COG0488	(ABC) transporter
H1I76_RS07570	COG0589	response to stress
H1I76_RS07595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1I76_RS07605	COG3135	benzoate transporter
H1I76_RS07610	COG1522	sequence-specific DNA binding
H1I76_RS07620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1I76_RS07625	COG0583	DNA-binding transcription factor activity
H1I76_RS07635	COG0183	Belongs to the thiolase family
H1I76_RS07645	COG2030	dehydratase
H1I76_RS07650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I76_RS07665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1I76_RS07675	COG0824	Thioesterase
H1I76_RS07680	COG1454	alcohol dehydrogenase
H1I76_RS07690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1I76_RS07710	COG0069	glutamate synthase activity
H1I76_RS07730	COG2814	Major facilitator Superfamily
H1I76_RS07745	COG0511	ligase activity, forming carbon-carbon bonds
H1I76_RS07765	COG1116	anion transmembrane transporter activity
H1I76_RS07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I76_RS07770	COG0745	RESPONSE REGULATOR receiver
H1I76_RS07780	COG2146	nitrite reductase [NAD(P)H] activity
H1I76_RS07780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I76_RS07785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I76_RS07790	COG0243	molybdopterin cofactor binding
H1I76_RS07800	COG0243	molybdopterin cofactor binding
H1I76_RS07805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1I76_RS07820	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1I76_RS07820	COG0315	cyclic pyranopterin monophosphate synthase activity
H1I76_RS07825	COG0303	'Molybdopterin
H1I76_RS07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I76_RS07840	COG0697	spore germination
H1I76_RS07860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1I76_RS07865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I76_RS07920	COG2204	response regulator
H1I76_RS07925	COG3852	Histidine kinase
H1I76_RS07945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1I76_RS07950	COG0575	Belongs to the CDS family
H1I76_RS07985	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I76_RS08000	COG2137	regulation of response to DNA damage stimulus
H1I76_RS08010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1I76_RS08015	COG1011	Hydrolase
H1I76_RS08040	COG1522	sequence-specific DNA binding
H1I76_RS08050	COG1113	amino acid transport
H1I76_RS08065	COG0659	secondary active sulfate transmembrane transporter activity
H1I76_RS08070	COG2135	peptidase activity
H1I76_RS08085	COG5001	Diguanylate cyclase
H1I76_RS08085	COG3300	MHYT domain
H1I76_RS08105	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1I76_RS08105	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I76_RS08105	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1I76_RS08110	COG1105	Belongs to the carbohydrate kinase PfkB family
H1I76_RS08115	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1I76_RS08115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I76_RS08145	COG0024	Methionine aminopeptidase
H1I76_RS08150	COG0583	DNA-binding transcription factor activity
H1I76_RS08160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1I76_RS08165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1I76_RS08170	COG0516	GMP reductase activity
H1I76_RS08170	COG0517	IMP dehydrogenase activity
H1I76_RS08195	COG0552	protein localization to endoplasmic reticulum
H1I76_RS08205	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1I76_RS08220	COG4890	Cyd operon protein YbgT
H1I76_RS08225	COG1294	oxidase, subunit
H1I76_RS08240	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1I76_RS08250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1I76_RS08255	COG4774	siderophore transport
H1I76_RS08270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1I76_RS08275	COG0569	domain protein
H1I76_RS08280	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1I76_RS08310	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1I76_RS08315	COG0542	response to heat
H1I76_RS08340	COG1902	pentaerythritol trinitrate reductase activity
H1I76_RS08340	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I76_RS08385	COG2323	membrane
H1I76_RS08390	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1I76_RS08400	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I76_RS08405	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I76_RS08410	COG0183	Belongs to the thiolase family
H1I76_RS08415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1I76_RS08420	COG0596	Alpha beta hydrolase
H1I76_RS08425	COG2271	Major facilitator Superfamily
H1I76_RS08430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I76_RS08435	COG3485	protocatechuate 3,4-dioxygenase
H1I76_RS08440	COG3485	protocatechuate 3,4-dioxygenase
H1I76_RS08445	COG0710	3-dehydroquinate dehydratase activity
H1I76_RS08450	COG3420	alginic acid biosynthetic process
H1I76_RS08455	COG3659	wide pore channel activity
H1I76_RS08460	COG4993	Dehydrogenase
H1I76_RS08470	COG2391	methyltransferase activity
H1I76_RS08485	COG1414	Transcriptional regulator
H1I76_RS08490	COG0583	DNA-binding transcription factor activity
H1I76_RS08495	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS08520	COG2814	Major facilitator Superfamily
H1I76_RS08530	COG0154	amidase activity
H1I76_RS08550	COG4638	Rieske (2fe-2S)
H1I76_RS08560	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS08570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I76_RS08580	COG3733	amine oxidase
H1I76_RS08590	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS08600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I76_RS08605	COG0183	Belongs to the thiolase family
H1I76_RS08610	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I76_RS08615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I76_RS08625	COG4829	muconolactone delta-isomerase
H1I76_RS08630	COG4948	Mandelate Racemase Muconate Lactonizing
H1I76_RS08635	COG0583	DNA-binding transcription factor activity
H1I76_RS08645	COG2186	Transcriptional regulator
H1I76_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS08685	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS08690	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS08695	COG3829	transcription factor binding
H1I76_RS08705	COG3162	membrane
H1I76_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS08735	COG0753	catalase activity
H1I76_RS08755	COG1846	Transcriptional regulator
H1I76_RS08760	COG1902	pentaerythritol trinitrate reductase activity
H1I76_RS08760	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I76_RS08770	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H1I76_RS08800	COG1309	transcriptional regulator
H1I76_RS08810	COG1335	isochorismatase
H1I76_RS08815	COG0583	DNA-binding transcription factor activity
H1I76_RS08825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I76_RS08825	COG0475	glutathione-regulated potassium exporter activity
H1I76_RS08835	COG1473	amidohydrolase
H1I76_RS08845	COG2831	hemolysin activation secretion protein
H1I76_RS08850	COG3210	domain, Protein
H1I76_RS08880	COG2188	Transcriptional regulator
H1I76_RS08895	COG0583	DNA-binding transcription factor activity
H1I76_RS08925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I76_RS08945	COG1566	PFAM secretion protein HlyD family protein
H1I76_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS08965	COG0129	dihydroxy-acid dehydratase activity
H1I76_RS08975	COG0583	DNA-binding transcription factor activity
H1I76_RS08980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1I76_RS08990	COG2084	Dehydrogenase
H1I76_RS08995	COG2207	Transcriptional regulator
H1I76_RS09010	COG1064	alcohol dehydrogenase
H1I76_RS09020	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1I76_RS09025	COG1120	ATPase activity
H1I76_RS09045	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I76_RS09160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1I76_RS09210	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS09225	COG2207	Transcriptional regulator
H1I76_RS09235	COG2205	protein histidine kinase activity
H1I76_RS09240	COG0745	RESPONSE REGULATOR receiver
H1I76_RS09245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS09250	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I76_RS09255	COG1538	Outer membrane efflux protein
H1I76_RS09265	COG2072	flavoprotein involved in K transport
H1I76_RS09285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I76_RS09305	COG3539	Fimbrial protein
H1I76_RS09335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1I76_RS09345	COG0753	catalase activity
H1I76_RS09360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1I76_RS09420	COG1535	isochorismatase
H1I76_RS09420	COG3433	isochorismatase activity
H1I76_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS09430	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1I76_RS09435	COG4149	molybdate abc transporter
H1I76_RS09440	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1I76_RS09450	COG4638	Rieske (2fe-2S)
H1I76_RS09455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I76_RS09460	COG0543	2 iron, 2 sulfur cluster binding
H1I76_RS09460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I76_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS09500	COG2207	Transcriptional regulator
H1I76_RS09510	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS09515	COG2610	gluconate transmembrane transporter activity
H1I76_RS09525	COG0583	DNA-binding transcription factor activity
H1I76_RS09535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I76_RS09540	COG2031	fatty acid transporter
H1I76_RS09545	COG0183	Belongs to the thiolase family
H1I76_RS09550	COG0583	DNA-binding transcription factor activity
H1I76_RS09555	COG0583	DNA-binding transcription factor activity
H1I76_RS09570	COG1027	Aspartate ammonia-lyase
H1I76_RS09580	COG0477	Major facilitator Superfamily
H1I76_RS09600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I76_RS09605	COG4521	taurine ABC transporter
H1I76_RS09620	COG2188	Transcriptional regulator
H1I76_RS09630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1I76_RS09635	COG1733	regulation of RNA biosynthetic process
H1I76_RS09640	COG2207	Transcriptional regulator
H1I76_RS09640	COG3708	Transcriptional regulator
H1I76_RS09660	COG0730	response to heat
H1I76_RS09670	COG3453	Protein conserved in bacteria
H1I76_RS09670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I76_RS09680	COG3781	membrane
H1I76_RS09685	COG1063	alcohol dehydrogenase
H1I76_RS09695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1I76_RS09700	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1I76_RS09705	COG0022	dehydrogenase e1 component
H1I76_RS09710	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1I76_RS09715	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1I76_RS09730	COG3706	GGDEF domain
H1I76_RS09745	COG0133	tryptophan synthase activity
H1I76_RS09755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1I76_RS09790	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1I76_RS09815	COG2226	methyltransferase
H1I76_RS09870	COG0842	Transport permease protein
H1I76_RS09875	COG0842	Transport permease protein
H1I76_RS09880	COG1131	(ABC) transporter
H1I76_RS09895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1I76_RS09900	COG4773	Receptor
H1I76_RS09920	COG0730	response to heat
H1I76_RS09925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1I76_RS09945	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H1I76_RS09960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I76_RS10000	COG4264	IucA IucC family
H1I76_RS10005	COG4264	IucA IucC family
H1I76_RS10025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1I76_RS10040	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS10045	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS10050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1I76_RS10055	COG2207	Transcriptional regulator
H1I76_RS10060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I76_RS10065	COG0776	regulation of translation
H1I76_RS10090	COG0822	iron-sulfur transferase activity
H1I76_RS10095	COG0316	Belongs to the HesB IscA family
H1I76_RS10125	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1I76_RS10145	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1I76_RS10150	COG0702	epimerase
H1I76_RS10185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1I76_RS10195	COG0339	signal peptide processing
H1I76_RS10245	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1I76_RS10250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1I76_RS10280	COG0776	regulation of translation
H1I76_RS10345	COG0084	hydrolase, TatD family'
H1I76_RS10365	COG1663	tetraacyldisaccharide 4'-kinase activity
H1I76_RS10370	COG1132	(ABC) transporter
H1I76_RS10380	COG0811	peptide transport
H1I76_RS10385	COG1475	DNA binding
H1I76_RS10390	COG1192	Involved in chromosome partitioning
H1I76_RS10400	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1I76_RS10415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1I76_RS10420	COG0191	fructose-bisphosphate aldolase activity
H1I76_RS10440	COG0424	maF-like protein
H1I76_RS10445	COG2850	peptidyl-arginine hydroxylation
H1I76_RS10455	COG0640	Transcriptional regulator
H1I76_RS10470	COG3619	membrane
H1I76_RS10475	COG3122	Protein conserved in bacteria
H1I76_RS10480	COG1132	(ABC) transporter
H1I76_RS10500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1I76_RS10505	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1I76_RS10515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I76_RS10515	COG0506	proline dehydrogenase activity
H1I76_RS10515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1I76_RS10520	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H1I76_RS10535	COG3698	Phosphodiester glycosidase
H1I76_RS10545	COG2353	YceI-like domain
H1I76_RS10555	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1I76_RS10600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1I76_RS10600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1I76_RS10625	COG3539	Fimbrial protein
H1I76_RS10630	COG3121	Chaperone
H1I76_RS10655	COG0697	spore germination
H1I76_RS10665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I76_RS10675	COG0583	DNA-binding transcription factor activity
H1I76_RS10695	COG1309	transcriptional regulator
H1I76_RS10710	COG1522	sequence-specific DNA binding
H1I76_RS10720	COG1126	abc transporter atp-binding protein
H1I76_RS10725	COG0765	amino acid transport
H1I76_RS10730	COG0765	amino acid transport
H1I76_RS10760	COG1464	Belongs to the NlpA lipoprotein family
H1I76_RS10770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1I76_RS10775	COG2011	ABC-type metal ion transport system permease component
H1I76_RS10780	COG0012	GTP binding
H1I76_RS10805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1I76_RS10845	COG0386	Belongs to the glutathione peroxidase family
H1I76_RS10855	COG0436	Aminotransferase
H1I76_RS10895	COG3634	alkyl hydroperoxide reductase activity
H1I76_RS10910	COG0583	DNA-binding transcription factor activity
H1I76_RS10915	COG0798	PFAM Bile acid sodium symporter
H1I76_RS10920	COG0640	Transcriptional regulator
H1I76_RS10935	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1I76_RS10945	COG0583	DNA-binding transcription factor activity
H1I76_RS10955	COG1953	Uracil, thiamine, allantoin
H1I76_RS10965	COG2175	clavaminate synthase activity
H1I76_RS10970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I76_RS10975	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1I76_RS10980	COG4521	taurine ABC transporter
H1I76_RS10990	COG0477	Major facilitator Superfamily
H1I76_RS11015	COG1271	oxidase subunit
H1I76_RS11020	COG1294	oxidase, subunit
H1I76_RS11030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1I76_RS11050	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H1I76_RS11070	COG3052	prosthetic group binding
H1I76_RS11075	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H1I76_RS11085	COG2814	Major facilitator Superfamily
H1I76_RS11105	COG1346	cytolysis
H1I76_RS11115	COG0583	DNA-binding transcription factor activity
H1I76_RS11120	COG0625	glutathione transferase activity
H1I76_RS11125	COG0625	glutathione transferase activity
H1I76_RS11130	COG0583	DNA-binding transcription factor activity
H1I76_RS11145	COG1045	serine acetyltransferase
H1I76_RS11150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1I76_RS11155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1I76_RS11165	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS11180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I76_RS11185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I76_RS11190	COG1126	abc transporter atp-binding protein
H1I76_RS11195	COG0765	amino acid transport
H1I76_RS11200	COG0765	amino acid transport
H1I76_RS11220	COG0784	Response regulator, receiver
H1I76_RS11220	COG2205	protein histidine kinase activity
H1I76_RS11240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1I76_RS11260	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS11310	COG0583	DNA-binding transcription factor activity
H1I76_RS11330	COG0318	PFAM AMP-dependent synthetase and ligase
H1I76_RS11335	COG1309	transcriptional regulator
H1I76_RS11340	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS11345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1I76_RS11350	COG1024	Enoyl-CoA hydratase
H1I76_RS11355	COG4770	biotin carboxylase activity
H1I76_RS11365	COG0583	DNA-binding transcription factor activity
H1I76_RS11380	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS11390	COG2814	Major facilitator Superfamily
H1I76_RS11400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1I76_RS11405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1I76_RS11410	COG2814	Major facilitator Superfamily
H1I76_RS11415	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS11420	COG1024	Enoyl-CoA hydratase
H1I76_RS11425	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS11430	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I76_RS11435	COG0183	Belongs to the thiolase family
H1I76_RS11445	COG2814	Major facilitator Superfamily
H1I76_RS11455	COG1024	Enoyl-CoA hydratase
H1I76_RS11470	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS11475	COG2814	Major facilitator Superfamily
H1I76_RS11480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1I76_RS11485	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1I76_RS11500	COG3842	ATPase activity
H1I76_RS11505	COG1840	ABC-type Fe3 transport system, periplasmic component
H1I76_RS11515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I76_RS11520	COG1414	Transcriptional regulator
H1I76_RS11530	COG0583	DNA-binding transcription factor activity
H1I76_RS11535	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1I76_RS11540	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS11550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1I76_RS11560	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I76_RS11570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I76_RS11575	COG2267	carboxylic ester hydrolase activity
H1I76_RS11595	COG3038	cytochrome b561
H1I76_RS11600	COG0753	catalase activity
H1I76_RS11630	COG2050	protein possibly involved in aromatic compounds catabolism
H1I76_RS11640	COG3327	negative regulation of DNA-templated transcription, initiation
H1I76_RS11645	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1I76_RS11650	COG0183	Belongs to the thiolase family
H1I76_RS11655	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I76_RS11660	COG1024	Enoyl-CoA hydratase
H1I76_RS11665	COG1024	Enoyl-CoA hydratase
H1I76_RS11670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1I76_RS11675	COG2151	metal-sulfur cluster biosynthetic enzyme
H1I76_RS11680	COG3396	Phenylacetate-CoA oxygenase
H1I76_RS11685	COG3460	Phenylacetate-CoA oxygenase
H1I76_RS11690	COG3396	Phenylacetate-CoA oxygenase
H1I76_RS11695	COG2030	dehydratase
H1I76_RS11695	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS11700	COG1760	l-serine dehydratase
H1I76_RS11705	COG0531	amino acid
H1I76_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS11725	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I76_RS11735	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H1I76_RS11755	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I76_RS11765	COG0789	Transcriptional regulator
H1I76_RS11780	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1I76_RS11795	COG2807	transmembrane transport
H1I76_RS11800	COG0590	tRNA wobble adenosine to inosine editing
H1I76_RS11915	COG1116	anion transmembrane transporter activity
H1I76_RS11920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1I76_RS11930	COG0864	Transcriptional regulator
H1I76_RS11950	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1I76_RS11955	COG0439	Biotin carboxylase
H1I76_RS11970	COG1063	alcohol dehydrogenase
H1I76_RS11980	COG1309	transcriptional regulator
H1I76_RS12000	COG0038	chloride channel
H1I76_RS12005	COG4770	biotin carboxylase activity
H1I76_RS12025	COG1914	H( )-stimulated, divalent metal cation uptake system
H1I76_RS12030	COG0583	DNA-binding transcription factor activity
H1I76_RS12080	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1I76_RS12100	COG2814	Major facilitator Superfamily
H1I76_RS12110	COG1560	Kdo2-lipid A biosynthetic process
H1I76_RS12120	COG5006	permease, DMT superfamily
H1I76_RS12125	COG1522	sequence-specific DNA binding
H1I76_RS12140	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1I76_RS12150	COG4122	O-methyltransferase activity
H1I76_RS12180	COG1538	Outer membrane efflux protein
H1I76_RS12185	COG1137	ATPase activity
H1I76_RS12190	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1I76_RS12200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1I76_RS12205	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1I76_RS12205	COG0517	IMP dehydrogenase activity
H1I76_RS12240	COG2814	Major facilitator Superfamily
H1I76_RS12275	COG1278	Cold shock
H1I76_RS12280	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS12310	COG1570	exodeoxyribonuclease VII activity
H1I76_RS12360	COG0583	DNA-binding transcription factor activity
H1I76_RS12365	COG4638	Rieske (2fe-2S)
H1I76_RS12370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1I76_RS12375	COG0543	2 iron, 2 sulfur cluster binding
H1I76_RS12375	COG0633	Ferredoxin
H1I76_RS12380	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS12385	COG3135	benzoate transporter
H1I76_RS12390	COG2814	Major facilitator Superfamily
H1I76_RS12405	COG1643	Atp-dependent helicase
H1I76_RS12410	COG0450	alkyl hydroperoxide reductase
H1I76_RS12420	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1I76_RS12430	COG3634	alkyl hydroperoxide reductase activity
H1I76_RS12450	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1I76_RS12455	COG0625	glutathione transferase activity
H1I76_RS12465	COG2885	chlorophyll binding
H1I76_RS12500	COG0542	response to heat
H1I76_RS12515	COG1765	OsmC-like protein
H1I76_RS12535	COG0667	Aldo Keto reductase
H1I76_RS12550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1I76_RS12560	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1I76_RS12570	COG0527	aspartate kinase activity
H1I76_RS12580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1I76_RS12590	COG3038	cytochrome b561
H1I76_RS12595	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1I76_RS12600	COG2252	PERMEase
H1I76_RS12610	COG2072	flavoprotein involved in K transport
H1I76_RS12625	COG1741	Belongs to the pirin family
H1I76_RS12630	COG1309	transcriptional regulator
H1I76_RS12655	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1I76_RS12695	COG1902	pentaerythritol trinitrate reductase activity
H1I76_RS12695	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I76_RS12705	COG2203	Gaf domain
H1I76_RS12705	COG5001	Diguanylate cyclase
H1I76_RS12705	COG4251	negative regulation of phosphorylation
H1I76_RS12705	COG3706	GGDEF domain
H1I76_RS12715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I76_RS12735	COG4172	Belongs to the ABC transporter superfamily
H1I76_RS12740	COG4239	(ABC) transporter, permease
H1I76_RS12745	COG4174	ABC transporter (Permease)
H1I76_RS12755	COG0741	lytic transglycosylase activity
H1I76_RS12755	COG1388	LysM domain
H1I76_RS12755	COG1388	LysM domain
H1I76_RS12755	COG0741	lytic transglycosylase activity
H1I76_RS12760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I76_RS12800	COG0583	DNA-binding transcription factor activity
H1I76_RS12805	COG1279	arginine transmembrane transporter activity
H1I76_RS12825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I76_RS12830	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I76_RS12835	COG0006	proline dipeptidase activity
H1I76_RS12875	COG2194	sulfuric ester hydrolase activity
H1I76_RS12920	COG0739	heme binding
H1I76_RS13250	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1I76_RS13275	COG3384	dioxygenase
H1I76_RS13285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1I76_RS13290	COG2878	Part of a membrane complex involved in electron transport
H1I76_RS13295	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1I76_RS13320	COG0768	penicillin binding
H1I76_RS13325	COG0742	ribosomal rna small subunit methyltransferase
H1I76_RS13340	COG0830	nickel cation binding
H1I76_RS13390	COG1253	flavin adenine dinucleotide binding
H1I76_RS13395	COG2851	Citrate transporter
H1I76_RS13450	COG1773	rubredoxin
H1I76_RS13455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1I76_RS13465	COG0583	DNA-binding transcription factor activity
H1I76_RS13490	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1I76_RS13495	COG4181	ATPase activity
H1I76_RS13540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1I76_RS13560	COG0306	phosphate transporter
H1I76_RS13570	COG3958	Transketolase
H1I76_RS13575	COG3959	Transketolase, thiamine diphosphate binding domain
H1I76_RS13580	COG2271	Major facilitator Superfamily
H1I76_RS13585	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS13590	COG0583	DNA-binding transcription factor activity
H1I76_RS13605	COG2223	nitrite transmembrane transporter activity
H1I76_RS13610	COG2207	Transcriptional regulator
H1I76_RS13615	COG2066	Belongs to the glutaminase family
H1I76_RS13620	COG0242	peptide deformylase activity
H1I76_RS13625	COG0477	Major facilitator Superfamily
H1I76_RS13635	COG0028	Belongs to the TPP enzyme family
H1I76_RS13650	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS13655	COG2267	carboxylic ester hydrolase activity
H1I76_RS13665	COG2271	Major facilitator Superfamily
H1I76_RS13670	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1I76_RS13680	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS13700	COG1414	Transcriptional regulator
H1I76_RS13715	COG1024	Enoyl-CoA hydratase
H1I76_RS13725	COG1215	transferase activity, transferring glycosyl groups
H1I76_RS13730	COG1649	PFAM Uncharacterised BCR, COG1649
H1I76_RS13730	COG0726	polysaccharide deacetylase
H1I76_RS13740	COG4681	YaeQ
H1I76_RS13750	COG0523	cobalamin synthesis protein
H1I76_RS13760	COG1607	acyl-coa hydrolase
H1I76_RS13770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I76_RS13775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1I76_RS13780	COG1309	transcriptional regulator
H1I76_RS13805	COG2040	homocysteine
H1I76_RS13810	COG0531	amino acid
H1I76_RS13865	COG1595	DNA-templated transcription, initiation
H1I76_RS13875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I76_RS13880	COG0477	Major facilitator Superfamily
H1I76_RS13900	COG0084	hydrolase, TatD family'
H1I76_RS13935	COG0629	single-stranded DNA binding
H1I76_RS13990	COG0582	viral genome integration into host DNA
H1I76_RS14090	COG0592	DNA-directed DNA polymerase activity
H1I76_RS14130	COG2026	Addiction module toxin, RelE StbE family
H1I76_RS14325	COG1484	DNA-dependent DNA replication
H1I76_RS14415	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1I76_RS14485	COG0405	Gamma-glutamyltransferase
H1I76_RS14490	COG2814	Major facilitator Superfamily
H1I76_RS14500	COG2050	protein possibly involved in aromatic compounds catabolism
H1I76_RS14515	COG1090	epimerase
H1I76_RS14535	COG0420	3'-5' exonuclease activity
H1I76_RS14560	COG0735	belongs to the Fur family
H1I76_RS14565	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1I76_RS14585	COG0121	glutamine amidotransferase
H1I76_RS14600	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I76_RS14610	COG0210	DNA helicase
H1I76_RS14615	COG2885	chlorophyll binding
H1I76_RS14620	COG0204	Acyl-transferase
H1I76_RS14635	COG2894	cell division
H1I76_RS14660	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS14665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1I76_RS14665	COG1674	ftsk spoiiie
H1I76_RS14670	COG0492	ferredoxin-NADP+ reductase activity
H1I76_RS14675	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1I76_RS14685	COG0456	acetyltransferase
H1I76_RS14730	COG1981	membrane
H1I76_RS14745	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1I76_RS14745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I76_RS14765	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS14775	COG0657	acetylesterase activity
H1I76_RS14785	COG0473	3-isopropylmalate dehydrogenase activity
H1I76_RS14790	COG0583	DNA-binding transcription factor activity
H1I76_RS14810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1I76_RS14835	COG0564	pseudouridine synthase activity
H1I76_RS14845	COG0358	DNA primase activity
H1I76_RS14860	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1I76_RS14890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1I76_RS14920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1I76_RS14930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1I76_RS14930	COG0351	phosphomethylpyrimidine kinase
H1I76_RS14930	COG0352	thiamine-phosphate diphosphorylase activity
H1I76_RS14935	COG1652	LysM domain
H1I76_RS14960	COG1399	metal-binding, possibly nucleic acid-binding protein
H1I76_RS14965	COG3101	peptidyl-lysine hydroxylation
H1I76_RS14970	COG0009	L-threonylcarbamoyladenylate synthase
H1I76_RS14975	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1I76_RS14980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1I76_RS14995	COG4106	trans-aconitate 2-methyltransferase activity
H1I76_RS15010	COG0596	Alpha beta hydrolase
H1I76_RS15010	COG2226	methyltransferase
H1I76_RS15010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I76_RS15015	COG1877	trehalose-phosphatase activity
H1I76_RS15020	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1I76_RS15025	COG2223	nitrite transmembrane transporter activity
H1I76_RS15045	COG1196	nuclear chromosome segregation
H1I76_RS15055	COG0730	response to heat
H1I76_RS15070	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1I76_RS15080	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I76_RS15130	COG0489	protein tyrosine kinase activity
H1I76_RS15140	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I76_RS15140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I76_RS15170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1I76_RS15175	COG2081	HI0933 family
H1I76_RS15185	COG0668	transmembrane transport
H1I76_RS15205	COG0583	DNA-binding transcription factor activity
H1I76_RS15225	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1I76_RS15230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I76_RS15260	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1I76_RS15300	COG0745	RESPONSE REGULATOR receiver
H1I76_RS15320	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1I76_RS15330	COG2205	protein histidine kinase activity
H1I76_RS15400	COG4993	Dehydrogenase
H1I76_RS15425	COG0384	phenazine biosynthesis protein PhzF
H1I76_RS15445	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1I76_RS15460	COG0583	DNA-binding transcription factor activity
H1I76_RS15490	COG0583	DNA-binding transcription factor activity
H1I76_RS15505	COG0583	DNA-binding transcription factor activity
H1I76_RS15510	COG1053	succinate dehydrogenase
H1I76_RS15520	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1I76_RS15525	COG2814	Major facilitator Superfamily
H1I76_RS15530	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS15535	COG0583	DNA-binding transcription factor activity
H1I76_RS15540	COG1063	alcohol dehydrogenase
H1I76_RS15570	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1I76_RS15575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1I76_RS15580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I76_RS15595	COG3667	copper resistance
H1I76_RS15600	COG2132	Multicopper oxidase
H1I76_RS15610	COG0561	phosphatase activity
H1I76_RS15615	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1I76_RS15640	COG1214	PFAM Peptidase M22, glycoprotease
H1I76_RS15695	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1I76_RS15705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1I76_RS15710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1I76_RS15715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1I76_RS15775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1I76_RS15785	COG1846	Transcriptional regulator
H1I76_RS15790	COG1764	response to oxidative stress
H1I76_RS15840	COG0037	tRNA processing
H1I76_RS15850	COG0248	Ppx GppA phosphatase
H1I76_RS15880	COG0072	phenylalanine-tRNA ligase activity
H1I76_RS15920	COG1238	metal cluster binding
H1I76_RS15925	COG0625	glutathione transferase activity
H1I76_RS15940	COG0318	PFAM AMP-dependent synthetase and ligase
H1I76_RS15945	COG3028	Belongs to the UPF0307 family
H1I76_RS15950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1I76_RS15970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1I76_RS15975	COG0617	tRNA 3'-terminal CCA addition
H1I76_RS15980	COG1555	photosystem II stabilization
H1I76_RS15985	COG3956	TIGRFAM MazG family protein
H1I76_RS15995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1I76_RS16015	COG5002	protein histidine kinase activity
H1I76_RS16015	COG2205	protein histidine kinase activity
H1I76_RS16015	COG0784	Response regulator, receiver
H1I76_RS16020	COG1024	Enoyl-CoA hydratase
H1I76_RS16025	COG2084	Dehydrogenase
H1I76_RS16030	COG3622	Belongs to the hyi family
H1I76_RS16060	COG0697	spore germination
H1I76_RS16070	COG2814	Major facilitator Superfamily
H1I76_RS16075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1I76_RS16085	COG0583	DNA-binding transcription factor activity
H1I76_RS16095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1I76_RS16110	COG0084	hydrolase, TatD family'
H1I76_RS16125	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1I76_RS16155	COG0440	acetolactate synthase activity
H1I76_RS16160	COG0028	Belongs to the TPP enzyme family
H1I76_RS16185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1I76_RS16190	COG0577	efflux transmembrane transporter activity
H1I76_RS16190	COG1136	(ABC) transporter
H1I76_RS16195	COG1538	Outer membrane efflux protein
H1I76_RS16210	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1I76_RS16215	COG1162	GTPase activity
H1I76_RS16225	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1I76_RS16245	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H1I76_RS16250	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS16290	COG2986	histidine ammonia-lyase
H1I76_RS16305	COG0318	PFAM AMP-dependent synthetase and ligase
H1I76_RS16315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I76_RS16360	COG1426	Protein conserved in bacteria
H1I76_RS16395	COG0793	Belongs to the peptidase S41A family
H1I76_RS16410	COG2267	carboxylic ester hydrolase activity
H1I76_RS16420	COG1012	belongs to the aldehyde dehydrogenase family
H1I76_RS16425	COG3265	gluconokinase activity
H1I76_RS16435	COG0800	Aldolase
H1I76_RS16450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1I76_RS16455	COG0280	phosphate acetyltransferase
H1I76_RS16455	COG0857	belongs to the CobB CobQ family
H1I76_RS16460	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I76_RS16460	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1I76_RS16480	COG0740	serine-type endopeptidase activity
H1I76_RS16490	COG4774	siderophore transport
H1I76_RS16500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1I76_RS16510	COG2813	Specifically methylates the guanine in position
H1I76_RS16510	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1I76_RS16610	COG0788	formyltetrahydrofolate deformylase activity
H1I76_RS16635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I76_RS16635	COG4651	solute:proton antiporter activity
H1I76_RS16655	COG0724	RNA recognition motif
H1I76_RS16660	COG0210	DNA helicase
H1I76_RS16685	COG1733	regulation of RNA biosynthetic process
H1I76_RS16695	COG2900	Belongs to the SlyX family
H1I76_RS16700	COG0488	(ABC) transporter
H1I76_RS16705	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS16710	COG1560	Kdo2-lipid A biosynthetic process
H1I76_RS16720	COG1301	dicarboxylic acid transport
H1I76_RS16775	COG0473	3-isopropylmalate dehydrogenase activity
H1I76_RS16840	COG0583	DNA-binding transcription factor activity
H1I76_RS16850	COG0625	glutathione transferase activity
H1I76_RS16855	COG2378	regulation of single-species biofilm formation
H1I76_RS16860	COG0546	phosphoglycolate phosphatase activity
H1I76_RS16870	COG1530	ribonuclease E activity
H1I76_RS16875	COG0318	PFAM AMP-dependent synthetase and ligase
H1I76_RS16890	COG0583	DNA-binding transcription factor activity
H1I76_RS16895	COG4221	oxidoreductase activity
H1I76_RS16900	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1I76_RS16910	COG0534	Mate efflux family protein
H1I76_RS16925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1I76_RS16965	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1I76_RS16970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1I76_RS16985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1I76_RS16995	COG0644	oxidoreductase
H1I76_RS16995	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1I76_RS17000	COG0425	Belongs to the sulfur carrier protein TusA family
H1I76_RS17005	COG4535	Mg2 and Co2 transporter CorC
H1I76_RS17015	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1I76_RS17035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1I76_RS17040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1I76_RS17040	COG0475	glutathione-regulated potassium exporter activity
H1I76_RS17045	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H1I76_RS17055	COG0484	heat shock protein binding
H1I76_RS17060	COG0789	Transcriptional regulator
H1I76_RS17065	COG0598	Magnesium transport protein CorA
H1I76_RS17085	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1I76_RS17090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1I76_RS17095	COG1074	ATP-dependent DNA helicase activity
H1I76_RS17100	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1I76_RS17125	COG2226	methyltransferase
H1I76_RS17140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1I76_RS17145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1I76_RS17160	COG2111	Na H antiporter
H1I76_RS17160	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1I76_RS17165	COG1006	Multisubunit Na H antiporter MnhC subunit
H1I76_RS17170	COG0651	ATP synthesis coupled electron transport
H1I76_RS17175	COG1863	multisubunit Na H antiporter MnhE subunit
H1I76_RS17180	COG2212	antiporter activity
H1I76_RS17185	COG1320	monovalent cation:proton antiporter activity
H1I76_RS17200	COG0195	Participates in both transcription termination and antitermination
H1I76_RS17250	COG0237	dephospho-CoA kinase activity
H1I76_RS17260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1I76_RS17275	COG0497	DNA recombination
H1I76_RS17285	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1I76_RS17315	COG2169	Transcriptional regulator
H1I76_RS17315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1I76_RS17320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1I76_RS17385	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1I76_RS17400	COG0326	Molecular chaperone. Has ATPase activity
H1I76_RS17415	COG2056	Na+-H+ antiporter family
H1I76_RS17420	COG0596	Alpha beta hydrolase
H1I76_RS17515	COG0546	phosphoglycolate phosphatase activity
H1I76_RS17520	COG1716	ATPase activity
H1I76_RS17565	COG0181	hydroxymethylbilane synthase activity
H1I76_RS17575	COG3275	phosphorelay sensor kinase activity
H1I76_RS17595	COG1538	Outer membrane efflux protein
H1I76_RS17600	COG0697	spore germination
H1I76_RS17625	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1I76_RS17630	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1I76_RS17635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1I76_RS17640	COG0772	Belongs to the SEDS family
H1I76_RS17665	COG4974	Belongs to the 'phage' integrase family
H1I76_RS17670	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I76_RS17680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1I76_RS17690	COG2197	response regulator
H1I76_RS17705	COG0793	Belongs to the peptidase S41A family
H1I76_RS17710	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1I76_RS17715	COG0795	lipopolysaccharide-transporting ATPase activity
H1I76_RS17755	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I76_RS17755	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1I76_RS17765	COG0004	ammonium transporteR
H1I76_RS17770	COG0347	Belongs to the P(II) protein family
H1I76_RS17780	COG0606	chelatase, subunit chli
H1I76_RS17860	COG0659	secondary active sulfate transmembrane transporter activity
H1I76_RS17865	COG0589	response to stress
H1I76_RS17895	COG0606	chelatase, subunit chli
H1I76_RS17910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1I76_RS17925	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1I76_RS17940	COG0318	PFAM AMP-dependent synthetase and ligase
H1I76_RS17950	COG0477	Major facilitator Superfamily
H1I76_RS17955	COG2860	membrane
H1I76_RS17965	COG1253	flavin adenine dinucleotide binding
H1I76_RS17985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1I76_RS18020	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1I76_RS18030	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1I76_RS18065	COG1309	transcriptional regulator
H1I76_RS18100	COG0758	DNA mediated transformation
H1I76_RS18110	COG0697	spore germination
H1I76_RS18115	COG1309	transcriptional regulator
H1I76_RS18130	COG0386	Belongs to the glutathione peroxidase family
H1I76_RS18195	COG1121	(ABC) transporter
H1I76_RS18200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1I76_RS18205	COG1280	lysine exporter protein (LysE YggA)
H1I76_RS18210	COG2837	iron assimilation
H1I76_RS18220	COG0281	malic enzyme
H1I76_RS18265	COG0519	Catalyzes the synthesis of GMP from XMP
H1I76_RS18265	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1I76_RS18270	COG4399	Belongs to the UPF0754 family
H1I76_RS18275	COG2259	Doxx family
H1I76_RS18280	COG0586	Pfam SNARE associated Golgi protein
H1I76_RS18295	COG1192	Involved in chromosome partitioning
H1I76_RS18305	COG0271	Belongs to the BolA IbaG family
H1I76_RS18325	COG2267	carboxylic ester hydrolase activity
H1I76_RS18345	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1I76_RS18345	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1I76_RS18345	COG3321	synthase
H1I76_RS18345	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1I76_RS18350	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS18360	COG2197	response regulator
H1I76_RS18370	COG3916	Acyl-homoserine-lactone synthase
H1I76_RS18375	COG0477	Major facilitator Superfamily
H1I76_RS18380	COG1024	Enoyl-CoA hydratase
H1I76_RS18385	COG1024	Enoyl-CoA hydratase
H1I76_RS18390	COG1960	acyl-CoA dehydrogenase activity
H1I76_RS18395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1I76_RS18415	COG1113	amino acid transport
H1I76_RS18420	COG1113	amino acid transport
H1I76_RS18425	COG0251	oxidation-reduction process
H1I76_RS18465	COG0564	pseudouridine synthase activity
H1I76_RS18525	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1I76_RS18540	COG1802	Transcriptional regulator
H1I76_RS18550	COG1448	Aminotransferase
H1I76_RS18555	COG0277	FAD linked oxidase domain protein
H1I76_RS18565	COG2186	Transcriptional regulator
H1I76_RS18575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1I76_RS18580	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1I76_RS18595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1I76_RS18600	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1I76_RS18655	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1I76_RS18685	COG0728	peptidoglycan biosynthetic process
H1I76_RS18690	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1I76_RS18745	COG0546	phosphoglycolate phosphatase activity
H1I76_RS18750	COG1028	Short-chain dehydrogenase reductase Sdr
H1I76_RS18770	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I76_RS18775	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1I76_RS18780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1I76_RS18785	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1I76_RS18790	COG1116	anion transmembrane transporter activity
H1I76_RS18795	COG1309	transcriptional regulator
H1I76_RS18800	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1I76_RS18810	COG0196	riboflavin kinase activity
H1I76_RS18815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1I76_RS18825	COG1047	Peptidyl-prolyl cis-trans
H1I76_RS18865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1I76_RS18870	COG0657	acetylesterase activity
H1I76_RS18920	COG2951	lytic endotransglycosylase activity
H1I76_RS18925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1I76_RS18940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1I76_RS18950	COG0671	phosphoesterase, PA-phosphatase related
H1I76_RS18955	COG0861	Integral membrane protein TerC family
H1I76_RS18965	COG0754	glutathionylspermidine amidase activity
H1I76_RS18975	COG0402	S-adenosylhomocysteine deaminase activity
H1I76_RS18990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1I76_RS18995	COG1230	cation diffusion facilitator family transporter
H1I76_RS19010	COG0706	membrane insertase activity