locus-tag	class	description
N4T36_RS00115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS00120	COG1230	cation diffusion facilitator family transporter
N4T36_RS00130	COG0640	Transcriptional regulator
N4T36_RS00140	COG0789	Transcriptional regulator
N4T36_RS00250	COG1192	Involved in chromosome partitioning
N4T36_RS00255	COG1475	DNA binding
N4T36_RS00370	COG4974	Belongs to the 'phage' integrase family
N4T36_RS00500	COG4372	Transposase
N4T36_RS00510	COG0657	acetylesterase activity
N4T36_RS00535	COG2814	Major facilitator Superfamily
N4T36_RS00545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T36_RS00570	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T36_RS00600	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS00605	COG3657	addiction module killer protein
N4T36_RS00610	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T36_RS00630	COG0488	(ABC) transporter
N4T36_RS00635	COG3173	Aminoglycoside phosphotransferase
N4T36_RS00780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T36_RS00855	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS00935	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS01050	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
N4T36_RS01105	COG1525	nuclease
N4T36_RS01115	COG2189	Belongs to the N(4) N(6)-methyltransferase family
N4T36_RS01135	COG4372	Transposase
N4T36_RS01200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
N4T36_RS01280	COG4372	Transposase
N4T36_RS01305	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T36_RS01330	COG0860	N-Acetylmuramoyl-L-alanine amidase
N4T36_RS01360	COG0745	RESPONSE REGULATOR receiver
N4T36_RS01365	COG5002	protein histidine kinase activity
N4T36_RS01375	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T36_RS01395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
N4T36_RS01410	COG4372	Transposase
N4T36_RS01420	COG2963	transposase activity
N4T36_RS01445	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T36_RS01455	COG4372	Transposase
N4T36_RS01620	COG5410	chromosome segregation
N4T36_RS01750	COG3561	AntA/AntB antirepressor
N4T36_RS01760	COG0739	heme binding
N4T36_RS01840	COG0582	viral genome integration into host DNA
N4T36_RS01875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T36_RS01905	COG3620	sequence-specific DNA binding
N4T36_RS01935	COG0305	Participates in initiation and elongation during chromosome replication
N4T36_RS02060	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
N4T36_RS02080	COG5380	lipid catabolic process
N4T36_RS02085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
N4T36_RS02110	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
N4T36_RS02115	COG0277	FAD linked oxidase domain protein
N4T36_RS02130	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
N4T36_RS02135	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T36_RS02160	COG4372	Transposase
N4T36_RS02170	COG1289	transmembrane transporter activity
N4T36_RS02180	COG0628	permease
N4T36_RS02185	COG1192	Involved in chromosome partitioning
N4T36_RS02215	COG0833	amino acid
N4T36_RS02220	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T36_RS02225	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T36_RS02235	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS02275	COG0583	DNA-binding transcription factor activity
N4T36_RS02295	COG1106	Psort location Cytoplasmic, score
N4T36_RS02330	COG0517	IMP dehydrogenase activity
N4T36_RS02335	COG1983	PspC domain protein
N4T36_RS02345	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS02360	COG0408	coproporphyrinogen oxidase activity
N4T36_RS02380	COG0513	Belongs to the DEAD box helicase family
N4T36_RS02390	COG1127	ABC transporter
N4T36_RS02395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
N4T36_RS02405	COG2854	intermembrane phospholipid transfer
N4T36_RS02415	COG0598	Magnesium transport protein CorA
N4T36_RS02425	COG0494	nUDIX hydrolase
N4T36_RS02430	COG1040	competence protein
N4T36_RS02435	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
N4T36_RS02455	COG1946	Acyl-CoA thioesterase
N4T36_RS02460	COG1301	dicarboxylic acid transport
N4T36_RS02475	COG1959	2 iron, 2 sulfur cluster binding
N4T36_RS02480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS02480	COG1017	nitric oxide dioxygenase activity
N4T36_RS02490	COG0433	COG0433 Predicted ATPase
N4T36_RS02495	COG0626	cystathionine gamma-synthase activity
N4T36_RS02650	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS02655	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
N4T36_RS02685	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
N4T36_RS02690	COG0339	signal peptide processing
N4T36_RS02695	COG0557	exoribonuclease II activity
N4T36_RS02740	COG0179	Fumarylacetoacetate (FAA) hydrolase
N4T36_RS02750	COG0697	spore germination
N4T36_RS02755	COG1295	ribonuclease BN
N4T36_RS02790	COG1702	phosphate starvation-inducible protein PhoH
N4T36_RS02800	COG0741	lytic transglycosylase activity
N4T36_RS02800	COG1196	nuclear chromosome segregation
N4T36_RS02800	COG0739	heme binding
N4T36_RS02830	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
N4T36_RS02835	COG1183	phosphatidylcholine synthase activity
N4T36_RS02880	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS02885	COG1309	transcriptional regulator
N4T36_RS02900	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T36_RS02905	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS02925	COG2969	positive regulation of protein catabolic process
N4T36_RS02935	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
N4T36_RS02950	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
N4T36_RS02955	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
N4T36_RS02975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
N4T36_RS02985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
N4T36_RS02990	COG1408	metallophosphoesterase
N4T36_RS03000	COG2199	diguanylate cyclase activity
N4T36_RS03060	COG1607	acyl-coa hydrolase
N4T36_RS03090	COG2350	Protein conserved in bacteria
N4T36_RS03100	COG0613	PHP domain protein
N4T36_RS03105	COG3781	membrane
N4T36_RS03115	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
N4T36_RS03120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
N4T36_RS03130	COG1862	Preprotein translocase
N4T36_RS03190	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
N4T36_RS03210	COG0726	polysaccharide deacetylase
N4T36_RS03215	COG0463	Glycosyl transferase, family 2
N4T36_RS03220	COG0438	transferase activity, transferring glycosyl groups
N4T36_RS03245	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS03305	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS03310	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS03320	COG2205	protein histidine kinase activity
N4T36_RS03325	COG0745	RESPONSE REGULATOR receiver
N4T36_RS03330	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
N4T36_RS03345	COG0584	glycerophosphoryl diester phosphodiesterase
N4T36_RS03350	COG2096	Adenosyltransferase
N4T36_RS03355	COG4206	TonB-dependent receptor
N4T36_RS03400	COG0285	dihydrofolate synthase activity
N4T36_RS03420	COG0450	alkyl hydroperoxide reductase
N4T36_RS03435	COG0477	Major facilitator Superfamily
N4T36_RS03440	COG1272	protein, Hemolysin III
N4T36_RS03470	COG0183	Belongs to the thiolase family
N4T36_RS03475	COG2207	Transcriptional regulator
N4T36_RS03495	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T36_RS03515	COG0183	Belongs to the thiolase family
N4T36_RS03525	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
N4T36_RS03525	COG2885	chlorophyll binding
N4T36_RS03535	COG1690	Belongs to the RtcB family
N4T36_RS03540	COG0833	amino acid
N4T36_RS03550	COG2233	PERMEase
N4T36_RS03555	COG1217	gtp-binding protein TYPA
N4T36_RS03580	COG2094	Belongs to the DNA glycosylase MPG family
N4T36_RS03585	COG4772	TonB-dependent receptor
N4T36_RS03590	COG1902	pentaerythritol trinitrate reductase activity
N4T36_RS03605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T36_RS03610	COG0354	folic acid binding
N4T36_RS03620	COG3189	MarR family transcriptional regulator
N4T36_RS03625	COG2824	Alkylphosphonate utilization operon protein PhnA
N4T36_RS03630	COG3422	double-strand break repair
N4T36_RS03670	COG0840	transmembrane signaling receptor activity
N4T36_RS03690	COG5510	response to toxic substance
N4T36_RS03700	COG2832	Protein of unknown function (DUF454)
N4T36_RS03705	COG1376	ErfK ybiS ycfS ynhG family protein
N4T36_RS03745	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
N4T36_RS03755	COG1289	transmembrane transporter activity
N4T36_RS03760	COG2814	Major facilitator Superfamily
N4T36_RS03780	COG1115	amino acid carrier protein
N4T36_RS03785	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T36_RS03790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T36_RS03795	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
N4T36_RS03825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T36_RS03835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
N4T36_RS03840	COG1077	Cell shape determining protein MreB Mrl
N4T36_RS03845	COG1792	Involved in formation and maintenance of cell shape
N4T36_RS03850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
N4T36_RS03855	COG0424	maF-like protein
N4T36_RS03860	COG1530	ribonuclease E activity
N4T36_RS03870	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T36_RS03880	COG0560	Phosphoserine phosphatase
N4T36_RS03890	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T36_RS03915	COG2207	Transcriptional regulator
N4T36_RS03935	COG0464	growth
N4T36_RS03960	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS04015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T36_RS04025	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
N4T36_RS04040	COG0730	response to heat
N4T36_RS04050	COG1196	nuclear chromosome segregation
N4T36_RS04070	COG2223	nitrite transmembrane transporter activity
N4T36_RS04075	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
N4T36_RS04080	COG1877	trehalose-phosphatase activity
N4T36_RS04085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T36_RS04085	COG0596	Alpha beta hydrolase
N4T36_RS04085	COG2226	methyltransferase
N4T36_RS04100	COG4106	trans-aconitate 2-methyltransferase activity
N4T36_RS04115	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
N4T36_RS04120	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
N4T36_RS04125	COG0009	L-threonylcarbamoyladenylate synthase
N4T36_RS04130	COG3101	peptidyl-lysine hydroxylation
N4T36_RS04135	COG1399	metal-binding, possibly nucleic acid-binding protein
N4T36_RS04160	COG1652	LysM domain
N4T36_RS04165	COG0352	thiamine-phosphate diphosphorylase activity
N4T36_RS04165	COG0351	phosphomethylpyrimidine kinase
N4T36_RS04165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T36_RS04175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
N4T36_RS04205	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T36_RS04235	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
N4T36_RS04250	COG0358	DNA primase activity
N4T36_RS04260	COG0564	pseudouridine synthase activity
N4T36_RS04310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T36_RS04340	COG3620	sequence-specific DNA binding
N4T36_RS04370	COG0305	Participates in initiation and elongation during chromosome replication
N4T36_RS04460	COG5410	chromosome segregation
N4T36_RS04590	COG3561	AntA/AntB antirepressor
N4T36_RS04600	COG0739	heme binding
N4T36_RS04680	COG0582	viral genome integration into host DNA
N4T36_RS04690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T36_RS04710	COG0583	DNA-binding transcription factor activity
N4T36_RS04715	COG0473	3-isopropylmalate dehydrogenase activity
N4T36_RS04725	COG0657	acetylesterase activity
N4T36_RS04735	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS04755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T36_RS04755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
N4T36_RS04770	COG1981	membrane
N4T36_RS04815	COG0456	acetyltransferase
N4T36_RS04825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
N4T36_RS04830	COG0492	ferredoxin-NADP+ reductase activity
N4T36_RS04835	COG1674	ftsk spoiiie
N4T36_RS04840	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS04855	COG2894	cell division
N4T36_RS04870	COG0204	Acyl-transferase
N4T36_RS04875	COG2885	chlorophyll binding
N4T36_RS04880	COG0210	DNA helicase
N4T36_RS04890	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T36_RS04905	COG0121	glutamine amidotransferase
N4T36_RS04925	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
N4T36_RS04930	COG0735	belongs to the Fur family
N4T36_RS04955	COG0420	3'-5' exonuclease activity
N4T36_RS04975	COG1090	epimerase
N4T36_RS04990	COG2050	protein possibly involved in aromatic compounds catabolism
N4T36_RS05000	COG2814	Major facilitator Superfamily
N4T36_RS05005	COG0405	Gamma-glutamyltransferase
N4T36_RS05075	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
N4T36_RS05085	COG0477	Major facilitator Superfamily
N4T36_RS05090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T36_RS05100	COG1595	DNA-templated transcription, initiation
N4T36_RS05155	COG0531	amino acid
N4T36_RS05185	COG1309	transcriptional regulator
N4T36_RS05190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T36_RS05195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
N4T36_RS05205	COG1607	acyl-coa hydrolase
N4T36_RS05215	COG0523	cobalamin synthesis protein
N4T36_RS05225	COG4681	YaeQ
N4T36_RS05235	COG0726	polysaccharide deacetylase
N4T36_RS05235	COG1649	PFAM Uncharacterised BCR, COG1649
N4T36_RS05240	COG1215	transferase activity, transferring glycosyl groups
N4T36_RS05250	COG1024	Enoyl-CoA hydratase
N4T36_RS05265	COG1414	Transcriptional regulator
N4T36_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS05300	COG2271	Major facilitator Superfamily
N4T36_RS05310	COG2267	carboxylic ester hydrolase activity
N4T36_RS05315	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS05330	COG0028	Belongs to the TPP enzyme family
N4T36_RS05340	COG0477	Major facilitator Superfamily
N4T36_RS05345	COG0242	peptide deformylase activity
N4T36_RS05350	COG2066	Belongs to the glutaminase family
N4T36_RS05355	COG2207	Transcriptional regulator
N4T36_RS05360	COG2223	nitrite transmembrane transporter activity
N4T36_RS05375	COG0583	DNA-binding transcription factor activity
N4T36_RS05380	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS05385	COG2271	Major facilitator Superfamily
N4T36_RS05390	COG3959	Transketolase, thiamine diphosphate binding domain
N4T36_RS05395	COG3958	Transketolase
N4T36_RS05405	COG0306	phosphate transporter
N4T36_RS05425	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T36_RS05470	COG4181	ATPase activity
N4T36_RS05505	COG0583	DNA-binding transcription factor activity
N4T36_RS05515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T36_RS05520	COG1773	rubredoxin
N4T36_RS05575	COG2851	Citrate transporter
N4T36_RS05580	COG1253	flavin adenine dinucleotide binding
N4T36_RS05625	COG0804	urea catabolic process
N4T36_RS05635	COG0830	nickel cation binding
N4T36_RS05650	COG0742	ribosomal rna small subunit methyltransferase
N4T36_RS05655	COG0768	penicillin binding
N4T36_RS05680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
N4T36_RS05685	COG2878	Part of a membrane complex involved in electron transport
N4T36_RS05690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
N4T36_RS05700	COG3384	dioxygenase
N4T36_RS05730	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
N4T36_RS05915	COG5410	chromosome segregation
N4T36_RS06025	COG1196	nuclear chromosome segregation
N4T36_RS06025	COG0741	lytic transglycosylase activity
N4T36_RS06025	COG0739	heme binding
N4T36_RS06070	COG2194	sulfuric ester hydrolase activity
N4T36_RS06110	COG0006	proline dipeptidase activity
N4T36_RS06115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T36_RS06120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T36_RS06140	COG1279	arginine transmembrane transporter activity
N4T36_RS06145	COG0583	DNA-binding transcription factor activity
N4T36_RS06200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T36_RS06205	COG1388	LysM domain
N4T36_RS06205	COG0741	lytic transglycosylase activity
N4T36_RS06205	COG1388	LysM domain
N4T36_RS06205	COG0741	lytic transglycosylase activity
N4T36_RS06215	COG4174	ABC transporter (Permease)
N4T36_RS06220	COG4239	(ABC) transporter, permease
N4T36_RS06225	COG4172	Belongs to the ABC transporter superfamily
N4T36_RS06245	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T36_RS06265	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T36_RS06265	COG1902	pentaerythritol trinitrate reductase activity
N4T36_RS06275	COG0582	viral genome integration into host DNA
N4T36_RS06315	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS06330	COG1262	PFAM Formylglycine-generating sulfatase enzyme
N4T36_RS06375	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
N4T36_RS06380	COG2072	flavoprotein involved in K transport
N4T36_RS06385	COG0300	oxidoreductase activity
N4T36_RS06395	COG1309	transcriptional regulator
N4T36_RS06400	COG1741	Belongs to the pirin family
N4T36_RS06415	COG2072	flavoprotein involved in K transport
N4T36_RS06425	COG2252	PERMEase
N4T36_RS06430	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
N4T36_RS06435	COG3038	cytochrome b561
N4T36_RS06445	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
N4T36_RS06455	COG0527	aspartate kinase activity
N4T36_RS06615	COG5410	chromosome segregation
N4T36_RS06720	COG1598	PFAM Uncharacterised protein family UPF0150
N4T36_RS06745	COG0739	heme binding
N4T36_RS06815	COG0582	viral genome integration into host DNA
N4T36_RS06825	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
N4T36_RS06835	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
N4T36_RS06850	COG0667	Aldo Keto reductase
N4T36_RS06865	COG1765	OsmC-like protein
N4T36_RS06880	COG0542	response to heat
N4T36_RS06915	COG2885	chlorophyll binding
N4T36_RS06925	COG0625	glutathione transferase activity
N4T36_RS06930	COG0220	tRNA (guanine-N7-)-methyltransferase activity
N4T36_RS06950	COG3634	alkyl hydroperoxide reductase activity
N4T36_RS06960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
N4T36_RS06970	COG0450	alkyl hydroperoxide reductase
N4T36_RS06975	COG1643	Atp-dependent helicase
N4T36_RS06990	COG2814	Major facilitator Superfamily
N4T36_RS06995	COG3135	benzoate transporter
N4T36_RS07000	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS07005	COG0633	Ferredoxin
N4T36_RS07005	COG0543	2 iron, 2 sulfur cluster binding
N4T36_RS07015	COG4638	Rieske (2fe-2S)
N4T36_RS07025	COG0583	DNA-binding transcription factor activity
N4T36_RS07035	COG2871	sodium ion transport
N4T36_RS07120	COG1570	exodeoxyribonuclease VII activity
N4T36_RS07150	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS07155	COG1278	Cold shock
N4T36_RS07195	COG2814	Major facilitator Superfamily
N4T36_RS07255	COG0210	DNA helicase
N4T36_RS07265	COG5377	YqaJ viral recombinase family
N4T36_RS07490	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
N4T36_RS07500	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
N4T36_RS07505	COG1137	ATPase activity
N4T36_RS07510	COG1538	Outer membrane efflux protein
N4T36_RS07540	COG4122	O-methyltransferase activity
N4T36_RS07550	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
N4T36_RS07565	COG1522	sequence-specific DNA binding
N4T36_RS07570	COG5006	permease, DMT superfamily
N4T36_RS07580	COG1560	Kdo2-lipid A biosynthetic process
N4T36_RS07595	COG2814	Major facilitator Superfamily
N4T36_RS07620	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T36_RS07650	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T36_RS07695	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS07730	COG0583	DNA-binding transcription factor activity
N4T36_RS07735	COG1914	H( )-stimulated, divalent metal cation uptake system
N4T36_RS07755	COG4770	biotin carboxylase activity
N4T36_RS07760	COG0038	chloride channel
N4T36_RS07785	COG1063	alcohol dehydrogenase
N4T36_RS07800	COG0439	Biotin carboxylase
N4T36_RS07805	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T36_RS07810	COG1733	regulation of RNA biosynthetic process
N4T36_RS07820	COG0864	Transcriptional regulator
N4T36_RS07830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T36_RS07835	COG1116	anion transmembrane transporter activity
N4T36_RS07955	COG0590	tRNA wobble adenosine to inosine editing
N4T36_RS07960	COG2807	transmembrane transport
N4T36_RS07975	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
N4T36_RS07985	COG0789	Transcriptional regulator
N4T36_RS07995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T36_RS08015	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T36_RS08040	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS08045	COG0531	amino acid
N4T36_RS08050	COG1760	l-serine dehydratase
N4T36_RS08055	COG2030	dehydratase
N4T36_RS08055	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS08060	COG3396	Phenylacetate-CoA oxygenase
N4T36_RS08065	COG3460	Phenylacetate-CoA oxygenase
N4T36_RS08070	COG3396	Phenylacetate-CoA oxygenase
N4T36_RS08075	COG2151	metal-sulfur cluster biosynthetic enzyme
N4T36_RS08080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS08085	COG1024	Enoyl-CoA hydratase
N4T36_RS08090	COG1024	Enoyl-CoA hydratase
N4T36_RS08095	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T36_RS08100	COG0183	Belongs to the thiolase family
N4T36_RS08105	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
N4T36_RS08110	COG3327	negative regulation of DNA-templated transcription, initiation
N4T36_RS08120	COG2050	protein possibly involved in aromatic compounds catabolism
N4T36_RS08150	COG0753	catalase activity
N4T36_RS08155	COG3038	cytochrome b561
N4T36_RS08175	COG2267	carboxylic ester hydrolase activity
N4T36_RS08180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS08185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T36_RS08190	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS08200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T36_RS08215	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS08220	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T36_RS08225	COG0583	DNA-binding transcription factor activity
N4T36_RS08235	COG1414	Transcriptional regulator
N4T36_RS08240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T36_RS08250	COG1840	ABC-type Fe3 transport system, periplasmic component
N4T36_RS08255	COG3842	ATPase activity
N4T36_RS08270	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
N4T36_RS08275	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T36_RS08280	COG2814	Major facilitator Superfamily
N4T36_RS08285	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS08300	COG1024	Enoyl-CoA hydratase
N4T36_RS08315	COG2192	nodulation
N4T36_RS08320	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS08340	COG0183	Belongs to the thiolase family
N4T36_RS08345	COG1250	3-hydroxyacyl-CoA dehydrogenase
N4T36_RS08350	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS08355	COG1024	Enoyl-CoA hydratase
N4T36_RS08360	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS08365	COG2814	Major facilitator Superfamily
N4T36_RS08370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T36_RS08375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T36_RS08385	COG2814	Major facilitator Superfamily
N4T36_RS08395	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS08410	COG0583	DNA-binding transcription factor activity
N4T36_RS08420	COG4770	biotin carboxylase activity
N4T36_RS08425	COG1024	Enoyl-CoA hydratase
N4T36_RS08430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
N4T36_RS08435	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS08440	COG1309	transcriptional regulator
N4T36_RS08445	COG0318	PFAM AMP-dependent synthetase and ligase
N4T36_RS08465	COG0583	DNA-binding transcription factor activity
N4T36_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS08535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
N4T36_RS08555	COG0784	Response regulator, receiver
N4T36_RS08555	COG2205	protein histidine kinase activity
N4T36_RS08575	COG0765	amino acid transport
N4T36_RS08580	COG0765	amino acid transport
N4T36_RS08585	COG1126	abc transporter atp-binding protein
N4T36_RS08590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T36_RS08595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
N4T36_RS08615	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS08625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
N4T36_RS08630	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T36_RS08635	COG1045	serine acetyltransferase
N4T36_RS08650	COG0583	DNA-binding transcription factor activity
N4T36_RS08655	COG0625	glutathione transferase activity
N4T36_RS08660	COG0625	glutathione transferase activity
N4T36_RS08665	COG0583	DNA-binding transcription factor activity
N4T36_RS08675	COG1346	cytolysis
N4T36_RS08695	COG2814	Major facilitator Superfamily
N4T36_RS08705	COG0583	DNA-binding transcription factor activity
N4T36_RS08715	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
N4T36_RS08720	COG3052	prosthetic group binding
N4T36_RS08740	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
N4T36_RS08760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T36_RS08770	COG1294	oxidase, subunit
N4T36_RS08775	COG1271	oxidase subunit
N4T36_RS08795	COG0477	Major facilitator Superfamily
N4T36_RS08810	COG4521	taurine ABC transporter
N4T36_RS08820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T36_RS08825	COG2175	clavaminate synthase activity
N4T36_RS08835	COG1953	Uracil, thiamine, allantoin
N4T36_RS08845	COG0583	DNA-binding transcription factor activity
N4T36_RS08855	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
N4T36_RS08870	COG0640	Transcriptional regulator
N4T36_RS08875	COG0798	PFAM Bile acid sodium symporter
N4T36_RS08880	COG0583	DNA-binding transcription factor activity
N4T36_RS08895	COG3634	alkyl hydroperoxide reductase activity
N4T36_RS08930	COG1301	dicarboxylic acid transport
N4T36_RS08935	COG0436	Aminotransferase
N4T36_RS08945	COG0386	Belongs to the glutathione peroxidase family
N4T36_RS08960	COG0436	Aminotransferase
N4T36_RS08985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T36_RS09010	COG0012	GTP binding
N4T36_RS09015	COG2011	ABC-type metal ion transport system permease component
N4T36_RS09020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T36_RS09030	COG1464	Belongs to the NlpA lipoprotein family
N4T36_RS09060	COG0765	amino acid transport
N4T36_RS09065	COG0765	amino acid transport
N4T36_RS09070	COG1126	abc transporter atp-binding protein
N4T36_RS09080	COG1522	sequence-specific DNA binding
N4T36_RS09095	COG1309	transcriptional regulator
N4T36_RS09125	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
N4T36_RS09135	COG0697	spore germination
N4T36_RS09160	COG3121	Chaperone
N4T36_RS09165	COG3539	Fimbrial protein
N4T36_RS09190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
N4T36_RS09190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
N4T36_RS09235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
N4T36_RS09245	COG2353	YceI-like domain
N4T36_RS09255	COG3698	Phosphodiester glycosidase
N4T36_RS09270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
N4T36_RS09275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T36_RS09275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
N4T36_RS09275	COG0506	proline dehydrogenase activity
N4T36_RS09285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T36_RS09290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
N4T36_RS09310	COG1132	(ABC) transporter
N4T36_RS09315	COG3122	Protein conserved in bacteria
N4T36_RS09320	COG3619	membrane
N4T36_RS09330	COG0640	Transcriptional regulator
N4T36_RS09340	COG2850	peptidyl-arginine hydroxylation
N4T36_RS09345	COG0424	maF-like protein
N4T36_RS09365	COG0191	fructose-bisphosphate aldolase activity
N4T36_RS09370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T36_RS09385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
N4T36_RS09395	COG1192	Involved in chromosome partitioning
N4T36_RS09400	COG1475	DNA binding
N4T36_RS09405	COG0811	peptide transport
N4T36_RS09415	COG1132	(ABC) transporter
N4T36_RS09420	COG1663	tetraacyldisaccharide 4'-kinase activity
N4T36_RS09440	COG0084	hydrolase, TatD family'
N4T36_RS09505	COG0776	regulation of translation
N4T36_RS09535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
N4T36_RS09540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
N4T36_RS09590	COG0339	signal peptide processing
N4T36_RS09600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
N4T36_RS09635	COG0702	epimerase
N4T36_RS09640	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T36_RS09660	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
N4T36_RS09690	COG0316	Belongs to the HesB IscA family
N4T36_RS09695	COG0822	iron-sulfur transferase activity
N4T36_RS09720	COG0776	regulation of translation
N4T36_RS09725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
N4T36_RS09730	COG2207	Transcriptional regulator
N4T36_RS09735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T36_RS09740	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS09745	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS09760	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
N4T36_RS09775	COG2814	Major facilitator Superfamily
N4T36_RS09780	COG4264	IucA IucC family
N4T36_RS09785	COG4264	IucA IucC family
N4T36_RS09795	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
N4T36_RS09825	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
N4T36_RS09845	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
N4T36_RS09850	COG0406	alpha-ribazole phosphatase activity
N4T36_RS09865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
N4T36_RS09870	COG0730	response to heat
N4T36_RS09890	COG4773	Receptor
N4T36_RS09895	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T36_RS09915	COG0842	Transport permease protein
N4T36_RS09920	COG0842	Transport permease protein
N4T36_RS09980	COG2226	methyltransferase
N4T36_RS10005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
N4T36_RS10040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T36_RS10050	COG0133	tryptophan synthase activity
N4T36_RS10065	COG3706	GGDEF domain
N4T36_RS10080	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T36_RS10085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
N4T36_RS10090	COG0022	dehydrogenase e1 component
N4T36_RS10095	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T36_RS10110	COG1063	alcohol dehydrogenase
N4T36_RS10115	COG3781	membrane
N4T36_RS10125	COG3453	Protein conserved in bacteria
N4T36_RS10125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T36_RS10140	COG0730	response to heat
N4T36_RS10155	COG2207	Transcriptional regulator
N4T36_RS10155	COG3708	Transcriptional regulator
N4T36_RS10160	COG1733	regulation of RNA biosynthetic process
N4T36_RS10165	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
N4T36_RS10175	COG2188	Transcriptional regulator
N4T36_RS10190	COG4521	taurine ABC transporter
N4T36_RS10195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T36_RS10255	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS10260	COG0431	NADPH-dependent FMN reductase
N4T36_RS10285	COG4691	Plasmid stability protein
N4T36_RS10320	COG0798	PFAM Bile acid sodium symporter
N4T36_RS10355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T36_RS10370	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T36_RS10375	COG1538	Outer membrane efflux protein
N4T36_RS10380	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
N4T36_RS10385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS10400	COG4372	Transposase
N4T36_RS10410	COG2963	transposase activity
N4T36_RS10435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
N4T36_RS10470	COG0477	Major facilitator Superfamily
N4T36_RS10480	COG1027	Aspartate ammonia-lyase
N4T36_RS10495	COG0583	DNA-binding transcription factor activity
N4T36_RS10500	COG0583	DNA-binding transcription factor activity
N4T36_RS10505	COG0183	Belongs to the thiolase family
N4T36_RS10510	COG2031	fatty acid transporter
N4T36_RS10525	COG0583	DNA-binding transcription factor activity
N4T36_RS10535	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS10550	COG1309	transcriptional regulator
N4T36_RS10570	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS10575	COG2207	Transcriptional regulator
N4T36_RS10590	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS10600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS10615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS10615	COG0543	2 iron, 2 sulfur cluster binding
N4T36_RS10620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
N4T36_RS10625	COG4638	Rieske (2fe-2S)
N4T36_RS10635	COG0725	ABC transporter, periplasmic molybdate-binding protein
N4T36_RS10640	COG4149	molybdate abc transporter
N4T36_RS10645	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
N4T36_RS10650	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS10655	COG1535	isochorismatase
N4T36_RS10655	COG3433	isochorismatase activity
N4T36_RS10735	COG0753	catalase activity
N4T36_RS10745	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
N4T36_RS10780	COG2205	protein histidine kinase activity
N4T36_RS10800	COG2814	Major facilitator Superfamily
N4T36_RS10825	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
N4T36_RS10870	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS10925	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
N4T36_RS10950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T36_RS10960	COG1064	alcohol dehydrogenase
N4T36_RS10965	COG2207	Transcriptional regulator
N4T36_RS10970	COG2084	Dehydrogenase
N4T36_RS10980	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
N4T36_RS10985	COG0583	DNA-binding transcription factor activity
N4T36_RS10995	COG0129	dihydroxy-acid dehydratase activity
N4T36_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS11005	COG1846	Transcriptional regulator
N4T36_RS11010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS11015	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS11050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
N4T36_RS11085	COG0583	DNA-binding transcription factor activity
N4T36_RS11100	COG2188	Transcriptional regulator
N4T36_RS11180	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS11185	COG0583	DNA-binding transcription factor activity
N4T36_RS11190	COG1414	Transcriptional regulator
N4T36_RS11205	COG2391	methyltransferase activity
N4T36_RS11210	COG3293	Transposase
N4T36_RS11220	COG4993	Dehydrogenase
N4T36_RS11225	COG3659	wide pore channel activity
N4T36_RS11230	COG3420	alginic acid biosynthetic process
N4T36_RS11235	COG0710	3-dehydroquinate dehydratase activity
N4T36_RS11240	COG3485	protocatechuate 3,4-dioxygenase
N4T36_RS11245	COG3485	protocatechuate 3,4-dioxygenase
N4T36_RS11250	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
N4T36_RS11255	COG2271	Major facilitator Superfamily
N4T36_RS11260	COG0596	Alpha beta hydrolase
N4T36_RS11265	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
N4T36_RS11270	COG0183	Belongs to the thiolase family
N4T36_RS11275	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
N4T36_RS11280	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
N4T36_RS11290	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
N4T36_RS11295	COG2323	membrane
N4T36_RS11340	COG0446	pyridine nucleotide-disulphide oxidoreductase
N4T36_RS11340	COG1902	pentaerythritol trinitrate reductase activity
N4T36_RS11365	COG0542	response to heat
N4T36_RS11370	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
N4T36_RS11410	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
N4T36_RS11415	COG0569	domain protein
N4T36_RS11420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
N4T36_RS11445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
N4T36_RS11455	COG1585	Membrane protein implicated in regulation of membrane protease activity
N4T36_RS11475	COG1294	oxidase, subunit
N4T36_RS11480	COG4890	Cyd operon protein YbgT
N4T36_RS11495	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
N4T36_RS11505	COG0552	protein localization to endoplasmic reticulum
N4T36_RS11530	COG0516	GMP reductase activity
N4T36_RS11530	COG0517	IMP dehydrogenase activity
N4T36_RS11535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
N4T36_RS11540	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
N4T36_RS11550	COG0583	DNA-binding transcription factor activity
N4T36_RS11555	COG0024	Methionine aminopeptidase
N4T36_RS11585	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
N4T36_RS11585	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T36_RS11590	COG1105	Belongs to the carbohydrate kinase PfkB family
N4T36_RS11595	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
N4T36_RS11595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T36_RS11595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
N4T36_RS11615	COG3300	MHYT domain
N4T36_RS11615	COG5001	Diguanylate cyclase
N4T36_RS11630	COG2135	peptidase activity
N4T36_RS11635	COG0659	secondary active sulfate transmembrane transporter activity
N4T36_RS11655	COG1113	amino acid transport
N4T36_RS11665	COG1522	sequence-specific DNA binding
N4T36_RS11690	COG1011	Hydrolase
N4T36_RS11695	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
N4T36_RS11705	COG2137	regulation of response to DNA damage stimulus
N4T36_RS11720	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
N4T36_RS11755	COG0575	Belongs to the CDS family
N4T36_RS11760	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
N4T36_RS11785	COG3852	Histidine kinase
N4T36_RS11790	COG2204	response regulator
N4T36_RS11845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T36_RS11850	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
N4T36_RS11870	COG0697	spore germination
N4T36_RS11875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T36_RS11885	COG0303	'Molybdopterin
N4T36_RS11890	COG0315	cyclic pyranopterin monophosphate synthase activity
N4T36_RS11890	COG0521	Mo-molybdopterin cofactor biosynthetic process
N4T36_RS11905	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
N4T36_RS11910	COG0243	molybdopterin cofactor binding
N4T36_RS11920	COG0243	molybdopterin cofactor binding
N4T36_RS11925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T36_RS11930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
N4T36_RS11930	COG2146	nitrite reductase [NAD(P)H] activity
N4T36_RS11940	COG0745	RESPONSE REGULATOR receiver
N4T36_RS11945	COG1116	anion transmembrane transporter activity
N4T36_RS11945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T36_RS11960	COG0511	ligase activity, forming carbon-carbon bonds
N4T36_RS11975	COG2814	Major facilitator Superfamily
N4T36_RS11995	COG0069	glutamate synthase activity
N4T36_RS12015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
N4T36_RS12025	COG1454	alcohol dehydrogenase
N4T36_RS12030	COG0824	Thioesterase
N4T36_RS12055	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T36_RS12060	COG2030	dehydratase
N4T36_RS12070	COG0183	Belongs to the thiolase family
N4T36_RS12080	COG0583	DNA-binding transcription factor activity
N4T36_RS12085	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
N4T36_RS12095	COG1522	sequence-specific DNA binding
N4T36_RS12100	COG3135	benzoate transporter
N4T36_RS12140	COG0589	response to stress
N4T36_RS12145	COG0488	(ABC) transporter
N4T36_RS12165	COG4773	Receptor
N4T36_RS12195	COG0668	transmembrane transport
N4T36_RS12205	COG1309	transcriptional regulator
N4T36_RS12225	COG1605	Chorismate mutase
N4T36_RS12245	COG0308	aminopeptidase N
N4T36_RS12270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T36_RS12275	COG1454	alcohol dehydrogenase
N4T36_RS12295	COG0531	amino acid
N4T36_RS12300	COG4303	Ethanolamine ammonia lyase large subunit
N4T36_RS12305	COG4302	ethanolamine ammonia-lyase activity
N4T36_RS12310	COG0519	Catalyzes the synthesis of GMP from XMP
N4T36_RS12310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T36_RS12315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T36_RS12340	COG0697	spore germination
N4T36_RS12345	COG1923	regulation of RNA biosynthetic process
N4T36_RS12355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
N4T36_RS12360	COG0802	atpase or kinase
N4T36_RS12380	COG1187	pseudouridine synthase activity
N4T36_RS12395	COG0583	DNA-binding transcription factor activity
N4T36_RS12410	COG2814	Major facilitator Superfamily
N4T36_RS12415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
N4T36_RS12495	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS12505	COG2963	transposase activity
N4T36_RS12515	COG4372	Transposase
N4T36_RS12545	COG0592	DNA-directed DNA polymerase activity
N4T36_RS12585	COG2026	Addiction module toxin, RelE StbE family
N4T36_RS12805	COG1484	DNA-dependent DNA replication
N4T36_RS12900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
N4T36_RS12940	COG0729	surface antigen
N4T36_RS12960	COG0174	glutamine synthetase
N4T36_RS12965	COG0745	RESPONSE REGULATOR receiver
N4T36_RS12970	COG2205	protein histidine kinase activity
N4T36_RS12980	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
N4T36_RS12985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
N4T36_RS13010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS13015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T36_RS13020	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS13050	COG0583	DNA-binding transcription factor activity
N4T36_RS13065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T36_RS13075	COG3658	cytochrome
N4T36_RS13080	COG1215	transferase activity, transferring glycosyl groups
N4T36_RS13110	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
N4T36_RS13115	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
N4T36_RS13125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
N4T36_RS13150	COG0305	Participates in initiation and elongation during chromosome replication
N4T36_RS13155	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
N4T36_RS13165	COG1305	Transglutaminase-like
N4T36_RS13175	COG2308	Evidence 4 Homologs of previously reported genes of
N4T36_RS13205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
N4T36_RS13210	COG0138	bifunctional purine biosynthesis protein purh
N4T36_RS13215	COG0151	Belongs to the GarS family
N4T36_RS13220	COG1464	Belongs to the NlpA lipoprotein family
N4T36_RS13225	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
N4T36_RS13230	COG2011	ABC-type metal ion transport system permease component
N4T36_RS13235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T36_RS13245	COG1301	dicarboxylic acid transport
N4T36_RS13280	COG1794	racemase activity, acting on amino acids and derivatives
N4T36_RS13290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
N4T36_RS13290	COG3008	intermembrane lipid transfer
N4T36_RS13295	COG2995	paraquat-inducible protein a
N4T36_RS13305	COG2985	domain, Protein
N4T36_RS13340	COG0477	Major facilitator Superfamily
N4T36_RS13390	COG2186	Transcriptional regulator
N4T36_RS13400	COG0786	glutamate:sodium symporter activity
N4T36_RS13405	COG3243	poly(R)-hydroxyalkanoic acid synthase
N4T36_RS13430	COG3111	PFAM Bacterial OB fold (BOF) protein
N4T36_RS13510	COG3210	domain, Protein
N4T36_RS13510	COG3210	domain, Protein
N4T36_RS13515	COG2831	hemolysin activation secretion protein
N4T36_RS13570	COG1610	YqeY-like protein
N4T36_RS13600	COG1286	toxin biosynthetic process
N4T36_RS13630	COG0778	Nitroreductase
N4T36_RS13640	COG0513	Belongs to the DEAD box helicase family
N4T36_RS13665	COG2363	Small membrane protein
N4T36_RS13695	COG1234	tRNA 3'-trailer cleavage
N4T36_RS13700	COG2195	Cleaves the N-terminal amino acid of tripeptides
N4T36_RS13710	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
N4T36_RS13720	COG2819	hydrolase of the alpha beta superfamily
N4T36_RS13725	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS13730	COG1301	dicarboxylic acid transport
N4T36_RS13735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
N4T36_RS13740	COG3139	Protein of unknown function (DUF1315)
N4T36_RS13745	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
N4T36_RS13750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
N4T36_RS13760	COG0494	nUDIX hydrolase
N4T36_RS13770	COG0642	Histidine kinase
N4T36_RS13785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
N4T36_RS13795	COG1720	tRNA m6t6A37 methyltransferase activity
N4T36_RS13810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T36_RS13815	COG0826	peptidase U32
N4T36_RS13820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T36_RS13830	COG4598	ABC transporter
N4T36_RS13835	COG4160	amino acid transport
N4T36_RS13840	COG4215	(ABC) transporter
N4T36_RS13865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS13985	COG0739	heme binding
N4T36_RS14300	COG0582	viral genome integration into host DNA
N4T36_RS14305	COG1131	(ABC) transporter
N4T36_RS14310	COG0842	Transport permease protein
N4T36_RS14325	COG0772	Belongs to the SEDS family
N4T36_RS14330	COG2951	lytic endotransglycosylase activity
N4T36_RS14355	COG2207	Transcriptional regulator
N4T36_RS14370	COG0052	Belongs to the universal ribosomal protein uS2 family
N4T36_RS14375	COG0024	Methionine aminopeptidase
N4T36_RS14385	COG2223	nitrite transmembrane transporter activity
N4T36_RS14395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T36_RS14400	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
N4T36_RS14405	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS14420	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
N4T36_RS14425	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
N4T36_RS14430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T36_RS14460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N4T36_RS14465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
N4T36_RS14470	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
N4T36_RS14505	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
N4T36_RS14515	COG0174	glutamine synthetase
N4T36_RS14530	COG0582	viral genome integration into host DNA
N4T36_RS14605	COG1598	PFAM Uncharacterised protein family UPF0150
N4T36_RS14725	COG5410	chromosome segregation
N4T36_RS14900	COG0512	Glutamine amidotransferase of anthranilate synthase
N4T36_RS14935	COG1529	Aldehyde oxidase and xanthine dehydrogenase
N4T36_RS14945	COG0302	gtp cyclohydrolase
N4T36_RS14970	COG3739	integral membrane protein
N4T36_RS14985	COG1169	isochorismate synthase
N4T36_RS14995	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
N4T36_RS15000	COG1132	(ABC) transporter
N4T36_RS15005	COG1132	(ABC) transporter
N4T36_RS15015	COG3433	isochorismatase activity
N4T36_RS15015	COG1535	isochorismatase
N4T36_RS15020	COG1021	2,3-dihydroxybenzoate-AMP ligase
N4T36_RS15025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T36_RS15035	COG4774	siderophore transport
N4T36_RS15040	COG4607	ABC-type enterochelin transport system periplasmic component
N4T36_RS15045	COG4604	ABC transporter, ATP-binding protein
N4T36_RS15050	COG4605	iron ion homeostasis
N4T36_RS15055	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
N4T36_RS15060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T36_RS15075	COG2964	Protein conserved in bacteria
N4T36_RS15085	COG1741	Belongs to the pirin family
N4T36_RS15105	COG2879	small protein
N4T36_RS15110	COG1966	Carbon starvation protein
N4T36_RS15130	COG4943	cyclic-guanylate-specific phosphodiesterase activity
N4T36_RS15150	COG2211	Major facilitator Superfamily
N4T36_RS15155	COG1067	ATP-dependent peptidase activity
N4T36_RS15160	COG0583	DNA-binding transcription factor activity
N4T36_RS15185	COG1686	Belongs to the peptidase S11 family
N4T36_RS15190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
N4T36_RS15225	COG0616	signal peptide processing
N4T36_RS15230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
N4T36_RS15240	COG0573	inorganic phosphate transmembrane transporter activity
N4T36_RS15245	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
N4T36_RS15250	COG1113	amino acid transport
N4T36_RS15255	COG3961	Belongs to the TPP enzyme family
N4T36_RS15260	COG1522	sequence-specific DNA binding
N4T36_RS15270	COG0076	glutamate decarboxylase activity
N4T36_RS15275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T36_RS15285	COG1309	transcriptional regulator
N4T36_RS15300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
N4T36_RS15335	COG0352	thiamine-phosphate diphosphorylase activity
N4T36_RS15360	COG0612	Peptidase, M16
N4T36_RS15370	COG1823	symporter activity
N4T36_RS15375	COG0583	DNA-binding transcription factor activity
N4T36_RS15380	COG0477	Major facilitator Superfamily
N4T36_RS15405	COG1187	pseudouridine synthase activity
N4T36_RS15420	COG1686	Belongs to the peptidase S11 family
N4T36_RS15425	COG1252	NADH dehydrogenase
N4T36_RS15435	COG0415	Belongs to the DNA photolyase family
N4T36_RS15450	COG1215	transferase activity, transferring glycosyl groups
N4T36_RS15480	COG2070	2-Nitropropane dioxygenase
N4T36_RS15535	COG0556	nucleotide-excision repair
N4T36_RS15545	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS15560	COG0436	Aminotransferase
N4T36_RS15600	COG4221	oxidoreductase activity
N4T36_RS15610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
N4T36_RS15615	COG1381	Involved in DNA repair and RecF pathway recombination
N4T36_RS15625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
N4T36_RS15640	COG0681	Belongs to the peptidase S26 family
N4T36_RS15655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
N4T36_RS15680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
N4T36_RS15685	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
N4T36_RS15695	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
N4T36_RS15700	COG4208	sulfate ABC transporter
N4T36_RS15705	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
N4T36_RS15710	COG0583	DNA-binding transcription factor activity
N4T36_RS15715	COG4625	pathogenesis
N4T36_RS15730	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
N4T36_RS15745	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
N4T36_RS15755	COG1051	belongs to the nudix hydrolase family
N4T36_RS15755	COG1056	cytidyltransferase-related domain
N4T36_RS15760	COG1024	Enoyl-CoA hydratase
N4T36_RS15775	COG2814	Major facilitator Superfamily
N4T36_RS15780	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
N4T36_RS15780	COG0047	phosphoribosylformylglycinamidine synthase activity
N4T36_RS15800	COG1473	amidohydrolase
N4T36_RS15805	COG0824	Thioesterase
N4T36_RS15825	COG0823	Involved in the tonB-independent uptake of proteins
N4T36_RS15845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T36_RS15880	COG0628	permease
N4T36_RS15890	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
N4T36_RS15895	COG0596	Alpha beta hydrolase
N4T36_RS15900	COG0616	signal peptide processing
N4T36_RS15900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
N4T36_RS15910	COG0658	competence protein
N4T36_RS15910	COG2333	competence protein COMEC
N4T36_RS15915	COG1136	(ABC) transporter
N4T36_RS15920	COG4591	ABC-type transport system involved in lipoprotein release permease component
N4T36_RS15955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS15975	COG0463	Glycosyl transferase, family 2
N4T36_RS16005	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
N4T36_RS16010	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS16020	COG0019	diaminopimelate decarboxylase activity
N4T36_RS16030	COG1113	amino acid transport
N4T36_RS16045	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
N4T36_RS16055	COG3339	Conserved Protein
N4T36_RS16060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
N4T36_RS16065	COG0243	molybdopterin cofactor binding
N4T36_RS16070	COG1929	Belongs to the glycerate kinase type-1 family
N4T36_RS16085	COG0778	Nitroreductase
N4T36_RS16130	COG3811	Belongs to the UPF0386 family
N4T36_RS16140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
N4T36_RS16165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
N4T36_RS16185	COG0741	lytic transglycosylase activity
N4T36_RS16205	COG0584	glycerophosphoryl diester phosphodiesterase
N4T36_RS16235	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N4T36_RS16240	COG1597	lipid kinase activity
N4T36_RS16255	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
N4T36_RS16260	COG0477	Major facilitator Superfamily
N4T36_RS16310	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
N4T36_RS16315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
N4T36_RS16340	COG0505	Belongs to the CarA family
N4T36_RS16360	COG0589	response to stress
N4T36_RS16375	COG2843	Capsule synthesis protein
N4T36_RS16395	COG2321	neutral zinc metallopeptidase
N4T36_RS16400	COG2354	Protein conserved in bacteria
N4T36_RS16420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
N4T36_RS16445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
N4T36_RS16450	COG1053	succinate dehydrogenase
N4T36_RS16455	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
N4T36_RS16460	COG2009	succinate dehydrogenase
N4T36_RS16495	COG2921	Belongs to the UPF0250 family
N4T36_RS16500	COG0321	lipoyl(octanoyl) transferase activity
N4T36_RS16515	COG0531	amino acid
N4T36_RS16525	COG1733	regulation of RNA biosynthetic process
N4T36_RS16530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
N4T36_RS16535	COG1648	precorrin-2 dehydrogenase activity
N4T36_RS16535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
N4T36_RS16550	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
N4T36_RS16575	COG0215	cysteine-tRNA ligase activity
N4T36_RS16580	COG0671	phosphoesterase, PA-phosphatase related
N4T36_RS16585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS16595	COG1538	Outer membrane efflux protein
N4T36_RS16600	COG0393	Putative heavy-metal-binding
N4T36_RS16605	COG0393	Putative heavy-metal-binding
N4T36_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS16625	COG0525	valine-tRNA ligase activity
N4T36_RS16650	COG0004	ammonium transporteR
N4T36_RS16660	COG0642	Histidine kinase
N4T36_RS16665	COG0745	RESPONSE REGULATOR receiver
N4T36_RS16670	COG2194	sulfuric ester hydrolase activity
N4T36_RS16690	COG1752	Esterase of the alpha-beta hydrolase superfamily
N4T36_RS16705	COG2315	Protein conserved in bacteria
N4T36_RS16710	COG0142	geranyltranstransferase activity
N4T36_RS16715	COG2828	Protein conserved in bacteria
N4T36_RS16720	COG1113	amino acid transport
N4T36_RS16730	COG0582	viral genome integration into host DNA
N4T36_RS16770	COG0305	Participates in initiation and elongation during chromosome replication
N4T36_RS16820	COG0489	protein tyrosine kinase activity
N4T36_RS16830	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T36_RS16830	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T36_RS16860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
N4T36_RS16865	COG2081	HI0933 family
N4T36_RS16875	COG0668	transmembrane transport
N4T36_RS16895	COG0583	DNA-binding transcription factor activity
N4T36_RS16915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
N4T36_RS16920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T36_RS16950	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
N4T36_RS16990	COG0745	RESPONSE REGULATOR receiver
N4T36_RS17010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
N4T36_RS17020	COG0384	phenazine biosynthesis protein PhzF
N4T36_RS17080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS17110	COG0583	DNA-binding transcription factor activity
N4T36_RS17125	COG0583	DNA-binding transcription factor activity
N4T36_RS17130	COG1053	succinate dehydrogenase
N4T36_RS17140	COG1804	L-carnitine dehydratase bile acid-inducible protein F
N4T36_RS17145	COG2814	Major facilitator Superfamily
N4T36_RS17150	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS17155	COG0583	DNA-binding transcription factor activity
N4T36_RS17160	COG1063	alcohol dehydrogenase
N4T36_RS17190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
N4T36_RS17195	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
N4T36_RS17200	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T36_RS17220	COG2132	Multicopper oxidase
N4T36_RS17230	COG0561	phosphatase activity
N4T36_RS17235	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
N4T36_RS17245	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
N4T36_RS17260	COG1214	PFAM Peptidase M22, glycoprotease
N4T36_RS17320	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
N4T36_RS17325	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
N4T36_RS17330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
N4T36_RS17390	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
N4T36_RS17400	COG1846	Transcriptional regulator
N4T36_RS17405	COG1764	response to oxidative stress
N4T36_RS17445	COG0037	tRNA processing
N4T36_RS17455	COG0248	Ppx GppA phosphatase
N4T36_RS17485	COG0072	phenylalanine-tRNA ligase activity
N4T36_RS17525	COG1238	metal cluster binding
N4T36_RS17530	COG0625	glutathione transferase activity
N4T36_RS17545	COG0318	PFAM AMP-dependent synthetase and ligase
N4T36_RS17550	COG3028	Belongs to the UPF0307 family
N4T36_RS17555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
N4T36_RS17575	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
N4T36_RS17580	COG0617	tRNA 3'-terminal CCA addition
N4T36_RS17585	COG1555	photosystem II stabilization
N4T36_RS17590	COG3956	TIGRFAM MazG family protein
N4T36_RS17600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T36_RS17620	COG0784	Response regulator, receiver
N4T36_RS17620	COG2205	protein histidine kinase activity
N4T36_RS17620	COG5002	protein histidine kinase activity
N4T36_RS17625	COG1024	Enoyl-CoA hydratase
N4T36_RS17630	COG2084	Dehydrogenase
N4T36_RS17635	COG3622	Belongs to the hyi family
N4T36_RS17665	COG0697	spore germination
N4T36_RS17675	COG2814	Major facilitator Superfamily
N4T36_RS17680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
N4T36_RS17690	COG0583	DNA-binding transcription factor activity
N4T36_RS17700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
N4T36_RS17715	COG0084	hydrolase, TatD family'
N4T36_RS17730	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
N4T36_RS17740	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS17750	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS17775	COG0440	acetolactate synthase activity
N4T36_RS17780	COG0028	Belongs to the TPP enzyme family
N4T36_RS17805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS17810	COG1136	(ABC) transporter
N4T36_RS17810	COG0577	efflux transmembrane transporter activity
N4T36_RS17815	COG1538	Outer membrane efflux protein
N4T36_RS17830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
N4T36_RS17835	COG1162	GTPase activity
N4T36_RS17845	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
N4T36_RS17885	COG1426	Protein conserved in bacteria
N4T36_RS17920	COG0793	Belongs to the peptidase S41A family
N4T36_RS17935	COG2267	carboxylic ester hydrolase activity
N4T36_RS17945	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS17950	COG3265	gluconokinase activity
N4T36_RS17960	COG0800	Aldolase
N4T36_RS17970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
N4T36_RS17975	COG0280	phosphate acetyltransferase
N4T36_RS17975	COG0857	belongs to the CobB CobQ family
N4T36_RS17980	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T36_RS17980	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
N4T36_RS18000	COG0740	serine-type endopeptidase activity
N4T36_RS18010	COG4774	siderophore transport
N4T36_RS18020	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
N4T36_RS18030	COG2813	Specifically methylates the guanine in position
N4T36_RS18030	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
N4T36_RS18130	COG0788	formyltetrahydrofolate deformylase activity
N4T36_RS18155	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T36_RS18155	COG4651	solute:proton antiporter activity
N4T36_RS18175	COG0724	RNA recognition motif
N4T36_RS18180	COG0210	DNA helicase
N4T36_RS18205	COG1733	regulation of RNA biosynthetic process
N4T36_RS18215	COG2900	Belongs to the SlyX family
N4T36_RS18220	COG0488	(ABC) transporter
N4T36_RS18225	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS18230	COG1560	Kdo2-lipid A biosynthetic process
N4T36_RS18240	COG1301	dicarboxylic acid transport
N4T36_RS18295	COG0473	3-isopropylmalate dehydrogenase activity
N4T36_RS18360	COG0583	DNA-binding transcription factor activity
N4T36_RS18370	COG0625	glutathione transferase activity
N4T36_RS18375	COG2378	regulation of single-species biofilm formation
N4T36_RS18380	COG0546	phosphoglycolate phosphatase activity
N4T36_RS18390	COG1530	ribonuclease E activity
N4T36_RS18395	COG0318	PFAM AMP-dependent synthetase and ligase
N4T36_RS18410	COG0583	DNA-binding transcription factor activity
N4T36_RS18415	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS18420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
N4T36_RS18430	COG0534	Mate efflux family protein
N4T36_RS18445	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T36_RS18475	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
N4T36_RS18475	COG0493	'glutamate synthase
N4T36_RS18485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
N4T36_RS18490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
N4T36_RS18505	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T36_RS18515	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
N4T36_RS18515	COG0644	oxidoreductase
N4T36_RS18520	COG0425	Belongs to the sulfur carrier protein TusA family
N4T36_RS18525	COG4535	Mg2 and Co2 transporter CorC
N4T36_RS18535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
N4T36_RS18555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
N4T36_RS18560	COG0475	glutathione-regulated potassium exporter activity
N4T36_RS18560	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
N4T36_RS18575	COG0484	heat shock protein binding
N4T36_RS18580	COG0789	Transcriptional regulator
N4T36_RS18585	COG0598	Magnesium transport protein CorA
N4T36_RS18600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
N4T36_RS18605	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
N4T36_RS18610	COG1074	ATP-dependent DNA helicase activity
N4T36_RS18615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
N4T36_RS18635	COG2226	methyltransferase
N4T36_RS18645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
N4T36_RS18655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
N4T36_RS18670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
N4T36_RS18670	COG2111	Na H antiporter
N4T36_RS18675	COG1006	Multisubunit Na H antiporter MnhC subunit
N4T36_RS18680	COG0651	ATP synthesis coupled electron transport
N4T36_RS18685	COG1863	multisubunit Na H antiporter MnhE subunit
N4T36_RS18690	COG2212	antiporter activity
N4T36_RS18695	COG1320	monovalent cation:proton antiporter activity
N4T36_RS18710	COG0195	Participates in both transcription termination and antitermination
N4T36_RS18760	COG0237	dephospho-CoA kinase activity
N4T36_RS18770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
N4T36_RS18785	COG0497	DNA recombination
N4T36_RS18795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
N4T36_RS18825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
N4T36_RS18825	COG2169	Transcriptional regulator
N4T36_RS18830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
N4T36_RS18860	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS18910	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
N4T36_RS18925	COG0326	Molecular chaperone. Has ATPase activity
N4T36_RS18940	COG2056	Na+-H+ antiporter family
N4T36_RS18945	COG0596	Alpha beta hydrolase
N4T36_RS19045	COG0546	phosphoglycolate phosphatase activity
N4T36_RS19050	COG1716	ATPase activity
N4T36_RS19095	COG0181	hydroxymethylbilane synthase activity
N4T36_RS19105	COG3275	phosphorelay sensor kinase activity
N4T36_RS19125	COG1538	Outer membrane efflux protein
N4T36_RS19130	COG0697	spore germination
N4T36_RS19155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
N4T36_RS19160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
N4T36_RS19165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
N4T36_RS19170	COG0772	Belongs to the SEDS family
N4T36_RS19195	COG4974	Belongs to the 'phage' integrase family
N4T36_RS19200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T36_RS19210	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
N4T36_RS19220	COG2197	response regulator
N4T36_RS19235	COG0793	Belongs to the peptidase S41A family
N4T36_RS19240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
N4T36_RS19245	COG0795	lipopolysaccharide-transporting ATPase activity
N4T36_RS19285	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T36_RS19285	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
N4T36_RS19295	COG0004	ammonium transporteR
N4T36_RS19300	COG0347	Belongs to the P(II) protein family
N4T36_RS19320	COG0659	secondary active sulfate transmembrane transporter activity
N4T36_RS19325	COG0589	response to stress
N4T36_RS19370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T36_RS19380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T36_RS19405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
N4T36_RS19420	COG0318	PFAM AMP-dependent synthetase and ligase
N4T36_RS19430	COG0477	Major facilitator Superfamily
N4T36_RS19435	COG2860	membrane
N4T36_RS19445	COG1253	flavin adenine dinucleotide binding
N4T36_RS19465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
N4T36_RS19505	COG0655	NAD(P)H dehydrogenase (quinone) activity
N4T36_RS19515	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
N4T36_RS19585	COG0758	DNA mediated transformation
N4T36_RS19595	COG0697	spore germination
N4T36_RS19600	COG1309	transcriptional regulator
N4T36_RS19615	COG0386	Belongs to the glutathione peroxidase family
N4T36_RS19680	COG1121	(ABC) transporter
N4T36_RS19685	COG1108	ABC-type Mn2 Zn2 transport systems permease components
N4T36_RS19690	COG1280	lysine exporter protein (LysE YggA)
N4T36_RS19695	COG2837	iron assimilation
N4T36_RS19705	COG0281	malic enzyme
N4T36_RS19750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
N4T36_RS19750	COG0519	Catalyzes the synthesis of GMP from XMP
N4T36_RS19755	COG4399	Belongs to the UPF0754 family
N4T36_RS19760	COG2259	Doxx family
N4T36_RS19765	COG0586	Pfam SNARE associated Golgi protein
N4T36_RS19780	COG1192	Involved in chromosome partitioning
N4T36_RS19790	COG0271	Belongs to the BolA IbaG family
N4T36_RS19810	COG2267	carboxylic ester hydrolase activity
N4T36_RS19830	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
N4T36_RS19830	COG3321	synthase
N4T36_RS19830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
N4T36_RS19830	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
N4T36_RS19845	COG2826	transposase and inactivated derivatives, IS30 family
N4T36_RS19850	COG2197	response regulator
N4T36_RS19860	COG3916	Acyl-homoserine-lactone synthase
N4T36_RS19865	COG0477	Major facilitator Superfamily
N4T36_RS19870	COG1024	Enoyl-CoA hydratase
N4T36_RS19875	COG1024	Enoyl-CoA hydratase
N4T36_RS19880	COG1960	acyl-CoA dehydrogenase activity
N4T36_RS19885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T36_RS19905	COG1113	amino acid transport
N4T36_RS19910	COG1113	amino acid transport
N4T36_RS19915	COG0251	oxidation-reduction process
N4T36_RS19955	COG0564	pseudouridine synthase activity
N4T36_RS20015	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
N4T36_RS20030	COG1802	Transcriptional regulator
N4T36_RS20040	COG1448	Aminotransferase
N4T36_RS20045	COG0277	FAD linked oxidase domain protein
N4T36_RS20055	COG2186	Transcriptional regulator
N4T36_RS20065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
N4T36_RS20070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
N4T36_RS20085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
N4T36_RS20090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
N4T36_RS20095	COG1216	Glycosyl transferase, family 2
N4T36_RS20125	COG2089	acid synthase
N4T36_RS20140	COG1083	cytidylyl-transferase
N4T36_RS20145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
N4T36_RS20150	COG1086	Polysaccharide biosynthesis protein
N4T36_RS20155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
N4T36_RS20160	COG1596	polysaccharide export
N4T36_RS20185	COG0728	peptidoglycan biosynthetic process
N4T36_RS20190	COG3023	N-Acetylmuramoyl-L-alanine amidase
N4T36_RS20250	COG0546	phosphoglycolate phosphatase activity
N4T36_RS20255	COG1028	Short-chain dehydrogenase reductase Sdr
N4T36_RS20275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T36_RS20280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
N4T36_RS20285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
N4T36_RS20290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
N4T36_RS20295	COG1116	anion transmembrane transporter activity
N4T36_RS20300	COG1309	transcriptional regulator
N4T36_RS20305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
N4T36_RS20315	COG0196	riboflavin kinase activity
N4T36_RS20320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
N4T36_RS20330	COG1047	Peptidyl-prolyl cis-trans
N4T36_RS20370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
N4T36_RS20375	COG0657	acetylesterase activity
N4T36_RS20395	COG0583	DNA-binding transcription factor activity
N4T36_RS20425	COG2951	lytic endotransglycosylase activity
N4T36_RS20430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
N4T36_RS20445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
N4T36_RS20455	COG0671	phosphoesterase, PA-phosphatase related
N4T36_RS20460	COG0861	Integral membrane protein TerC family
N4T36_RS20470	COG0754	glutathionylspermidine amidase activity
N4T36_RS20480	COG0402	S-adenosylhomocysteine deaminase activity
N4T36_RS20495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
N4T36_RS20500	COG1230	cation diffusion facilitator family transporter
N4T36_RS20515	COG0706	membrane insertase activity
N4T36_RS20540	COG0592	DNA-directed DNA polymerase activity
N4T36_RS20550	COG0187	DNA topoisomerase II activity
N4T36_RS20560	COG0586	Pfam SNARE associated Golgi protein
N4T36_RS20565	COG0488	(ABC) transporter
N4T36_RS20590	COG0596	Alpha beta hydrolase
N4T36_RS20595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
N4T36_RS20600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
N4T36_RS20640	COG0733	neurotransmitter:sodium symporter activity
N4T36_RS20675	COG0583	DNA-binding transcription factor activity
N4T36_RS20680	COG2233	PERMEase
N4T36_RS20695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
N4T36_RS20730	COG2814	Major facilitator Superfamily
N4T36_RS20735	COG0656	L-ascorbic acid biosynthetic process
N4T36_RS20740	COG0583	DNA-binding transcription factor activity
N4T36_RS20755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
N4T36_RS20760	COG1064	alcohol dehydrogenase
N4T36_RS20780	COG1194	a g-specific adenine glycosylase
N4T36_RS20800	COG2983	Belongs to the UPF0260 family
N4T36_RS20820	COG1335	isochorismatase
N4T36_RS20825	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
N4T36_RS20845	COG2116	formate transmembrane transporter activity
N4T36_RS20850	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
N4T36_RS20945	COG0534	Mate efflux family protein
N4T36_RS20950	COG1683	Conserved Protein
N4T36_RS20970	COG0625	glutathione transferase activity
N4T36_RS20980	COG1113	amino acid transport
N4T36_RS20990	COG0523	cobalamin synthesis protein
N4T36_RS21000	COG2188	Transcriptional regulator
N4T36_RS21030	COG0010	Belongs to the arginase family
N4T36_RS21045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
N4T36_RS21050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
N4T36_RS21060	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
N4T36_RS21065	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
N4T36_RS21150	COG0534	Mate efflux family protein
N4T36_RS21155	COG0436	Aminotransferase
N4T36_RS21160	COG2733	membrane
N4T36_RS21175	COG2918	glutathione biosynthetic process
N4T36_RS21220	COG3150	esterase
N4T36_RS21230	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
N4T36_RS21240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
N4T36_RS21250	COG2233	PERMEase
N4T36_RS21255	COG2351	hydroxyisourate hydrolase activity
N4T36_RS21290	COG3706	GGDEF domain
N4T36_RS21305	COG1393	Belongs to the ArsC family
N4T36_RS21310	COG0708	Exodeoxyribonuclease III
N4T36_RS21325	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
N4T36_RS21345	COG0189	ligase activity
N4T36_RS21365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
N4T36_RS21375	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
N4T36_RS21390	COG4942	peptidase
N4T36_RS21400	COG0508	dehydrogenase complex catalyzes the overall conversion of
N4T36_RS21410	COG2119	membrane
N4T36_RS21415	COG4774	siderophore transport
N4T36_RS21420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
N4T36_RS21420	COG0426	domain, Protein
N4T36_RS21445	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
N4T36_RS21465	COG1902	pentaerythritol trinitrate reductase activity
N4T36_RS21470	COG1519	Transferase
N4T36_RS21475	COG1385	rRNA (uridine-N3-)-methyltransferase activity
N4T36_RS21480	COG0668	transmembrane transport
N4T36_RS21490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
N4T36_RS21495	COG1335	isochorismatase
N4T36_RS21500	COG1522	sequence-specific DNA binding
N4T36_RS21525	COG2205	protein histidine kinase activity
N4T36_RS21525	COG2198	Histidine kinase
N4T36_RS21525	COG0784	Response regulator, receiver
N4T36_RS21530	COG3162	membrane
N4T36_RS21535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
N4T36_RS21560	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
N4T36_RS21565	COG1309	transcriptional regulator
N4T36_RS21585	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
N4T36_RS21585	COG0351	phosphomethylpyrimidine kinase
N4T36_RS21585	COG0352	thiamine-phosphate diphosphorylase activity
N4T36_RS21595	COG2814	Major facilitator Superfamily
N4T36_RS21610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
N4T36_RS21620	COG1113	amino acid transport
N4T36_RS21630	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
N4T36_RS21635	COG1012	belongs to the aldehyde dehydrogenase family
N4T36_RS21645	COG1335	isochorismatase
N4T36_RS21680	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
N4T36_RS21680	COG2508	Transcriptional regulator
N4T36_RS21710	COG4372	Transposase
N4T36_RS21715	COG1113	amino acid transport
N4T36_RS21725	COG2814	Major facilitator Superfamily
N4T36_RS21730	COG0583	DNA-binding transcription factor activity
N4T36_RS21750	COG0667	Aldo Keto reductase
N4T36_RS21785	COG1733	regulation of RNA biosynthetic process
N4T36_RS21790	COG2249	NAD(P)H dehydrogenase (quinone) activity
N4T36_RS21855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
N4T36_RS21870	COG2329	Antibiotic biosynthesis monooxygenase
N4T36_RS21900	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
N4T36_RS21930	COG0427	acetyl-CoA hydrolase
N4T36_RS21955	COG0659	secondary active sulfate transmembrane transporter activity
N4T36_RS21960	COG4221	oxidoreductase activity
N4T36_RS21970	COG0488	(ABC) transporter
N4T36_RS22035	COG0833	amino acid
N4T36_RS22080	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
N4T36_RS22085	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
N4T36_RS22100	COG2226	methyltransferase
N4T36_RS22150	COG0067	glutamate synthase
N4T36_RS22150	COG0069	glutamate synthase activity
N4T36_RS22150	COG0070	glutamate synthase
N4T36_RS22155	COG0493	'glutamate synthase
N4T36_RS22165	COG1704	LemA family
N4T36_RS22170	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
N4T36_RS22190	COG3307	-O-antigen
N4T36_RS22210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
N4T36_RS22225	COG0194	GDP metabolic process