locus-tag	class	description
H0S62_RS00035	COG2226	methyltransferase
H0S62_RS00125	COG1610	YqeY-like protein
H0S62_RS00130	COG4783	chaperone-mediated protein folding
H0S62_RS00155	COG1286	toxin biosynthetic process
H0S62_RS00270	COG0778	Nitroreductase
H0S62_RS00280	COG0513	Belongs to the DEAD box helicase family
H0S62_RS00300	COG2363	Small membrane protein
H0S62_RS00350	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0S62_RS00360	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0S62_RS00375	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS00380	COG1301	dicarboxylic acid transport
H0S62_RS00385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0S62_RS00390	COG3139	Protein of unknown function (DUF1315)
H0S62_RS00395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0S62_RS00400	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0S62_RS00410	COG0494	nUDIX hydrolase
H0S62_RS00420	COG0642	Histidine kinase
H0S62_RS00425	COG0745	RESPONSE REGULATOR receiver
H0S62_RS00430	COG3111	PFAM Bacterial OB fold (BOF) protein
H0S62_RS00445	COG1720	tRNA m6t6A37 methyltransferase activity
H0S62_RS00460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0S62_RS00470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0S62_RS00480	COG4598	ABC transporter
H0S62_RS00485	COG4160	amino acid transport
H0S62_RS00490	COG4215	(ABC) transporter
H0S62_RS00505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0S62_RS00550	COG1131	(ABC) transporter
H0S62_RS00555	COG0842	Transport permease protein
H0S62_RS00570	COG0772	Belongs to the SEDS family
H0S62_RS00575	COG2951	lytic endotransglycosylase activity
H0S62_RS00600	COG2207	Transcriptional regulator
H0S62_RS00615	COG0052	Belongs to the universal ribosomal protein uS2 family
H0S62_RS00620	COG0024	Methionine aminopeptidase
H0S62_RS00630	COG2223	nitrite transmembrane transporter activity
H0S62_RS00640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0S62_RS00645	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0S62_RS00650	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS00665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0S62_RS00670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0S62_RS00675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0S62_RS00695	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0S62_RS00700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0S62_RS00705	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0S62_RS00740	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0S62_RS00750	COG0174	glutamine synthetase
H0S62_RS00755	COG3104	oligopeptide transport
H0S62_RS00765	COG0512	Glutamine amidotransferase of anthranilate synthase
H0S62_RS00770	COG0308	aminopeptidase N
H0S62_RS00840	COG3739	integral membrane protein
H0S62_RS00870	COG5265	(ABC) transporter
H0S62_RS00890	COG3433	isochorismatase activity
H0S62_RS00890	COG1535	isochorismatase
H0S62_RS00895	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0S62_RS00900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0S62_RS00910	COG4774	siderophore transport
H0S62_RS00915	COG4607	ABC-type enterochelin transport system periplasmic component
H0S62_RS00945	COG2964	Protein conserved in bacteria
H0S62_RS00955	COG1741	Belongs to the pirin family
H0S62_RS00970	COG4214	carbohydrate transport
H0S62_RS00985	COG2879	small protein
H0S62_RS00990	COG1966	Carbon starvation protein
H0S62_RS01010	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0S62_RS01035	COG1067	ATP-dependent peptidase activity
H0S62_RS01040	COG0583	DNA-binding transcription factor activity
H0S62_RS01065	COG1686	Belongs to the peptidase S11 family
H0S62_RS01070	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0S62_RS01105	COG0616	signal peptide processing
H0S62_RS01110	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0S62_RS01120	COG0573	inorganic phosphate transmembrane transporter activity
H0S62_RS01125	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0S62_RS01130	COG1113	amino acid transport
H0S62_RS01135	COG3961	Belongs to the TPP enzyme family
H0S62_RS01140	COG1522	sequence-specific DNA binding
H0S62_RS01150	COG0076	glutamate decarboxylase activity
H0S62_RS01155	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0S62_RS01180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0S62_RS01215	COG0352	thiamine-phosphate diphosphorylase activity
H0S62_RS01240	COG0612	Peptidase, M16
H0S62_RS01255	COG0583	DNA-binding transcription factor activity
H0S62_RS01260	COG0477	Major facilitator Superfamily
H0S62_RS01285	COG1187	pseudouridine synthase activity
H0S62_RS01300	COG1686	Belongs to the peptidase S11 family
H0S62_RS01305	COG1252	NADH dehydrogenase
H0S62_RS01315	COG0415	Belongs to the DNA photolyase family
H0S62_RS01335	COG1215	transferase activity, transferring glycosyl groups
H0S62_RS01365	COG2070	2-Nitropropane dioxygenase
H0S62_RS01420	COG0556	nucleotide-excision repair
H0S62_RS01440	COG0436	Aminotransferase
H0S62_RS01470	COG4221	oxidoreductase activity
H0S62_RS01485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0S62_RS01490	COG1381	Involved in DNA repair and RecF pathway recombination
H0S62_RS01500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0S62_RS01515	COG0681	Belongs to the peptidase S26 family
H0S62_RS01530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0S62_RS01550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0S62_RS01555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0S62_RS01560	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0S62_RS01570	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0S62_RS01575	COG4208	sulfate ABC transporter
H0S62_RS01580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0S62_RS01585	COG0583	DNA-binding transcription factor activity
H0S62_RS01590	COG4625	pathogenesis
H0S62_RS01605	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0S62_RS01620	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0S62_RS01630	COG1051	belongs to the nudix hydrolase family
H0S62_RS01630	COG1056	cytidyltransferase-related domain
H0S62_RS01635	COG1024	Enoyl-CoA hydratase
H0S62_RS01645	COG2814	Major facilitator Superfamily
H0S62_RS01650	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0S62_RS01650	COG0047	phosphoribosylformylglycinamidine synthase activity
H0S62_RS01670	COG1473	amidohydrolase
H0S62_RS01675	COG0824	Thioesterase
H0S62_RS01695	COG0823	Involved in the tonB-independent uptake of proteins
H0S62_RS01715	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0S62_RS01760	COG0628	permease
H0S62_RS01770	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0S62_RS01775	COG0596	Alpha beta hydrolase
H0S62_RS01780	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0S62_RS01780	COG0616	signal peptide processing
H0S62_RS01790	COG2333	competence protein COMEC
H0S62_RS01790	COG0658	competence protein
H0S62_RS01795	COG1136	(ABC) transporter
H0S62_RS01800	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0S62_RS01835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0S62_RS01855	COG0463	Glycosyl transferase, family 2
H0S62_RS01885	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0S62_RS01890	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS01900	COG0019	diaminopimelate decarboxylase activity
H0S62_RS01910	COG1113	amino acid transport
H0S62_RS01925	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H0S62_RS01935	COG3339	Conserved Protein
H0S62_RS01940	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0S62_RS01945	COG0243	molybdopterin cofactor binding
H0S62_RS01950	COG1929	Belongs to the glycerate kinase type-1 family
H0S62_RS01965	COG0778	Nitroreductase
H0S62_RS01990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0S62_RS02005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0S62_RS02025	COG0741	lytic transglycosylase activity
H0S62_RS02045	COG0584	glycerophosphoryl diester phosphodiesterase
H0S62_RS02050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0S62_RS02070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0S62_RS02075	COG1597	lipid kinase activity
H0S62_RS02090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0S62_RS02095	COG0477	Major facilitator Superfamily
H0S62_RS02165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0S62_RS02170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0S62_RS02195	COG0505	Belongs to the CarA family
H0S62_RS02210	COG1309	transcriptional regulator
H0S62_RS02215	COG0251	oxidation-reduction process
H0S62_RS02225	COG0589	response to stress
H0S62_RS02240	COG2843	Capsule synthesis protein
H0S62_RS02250	COG2826	transposase and inactivated derivatives, IS30 family
H0S62_RS02270	COG2321	neutral zinc metallopeptidase
H0S62_RS02275	COG2354	Protein conserved in bacteria
H0S62_RS02295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0S62_RS02320	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0S62_RS02325	COG1053	succinate dehydrogenase
H0S62_RS02330	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0S62_RS02335	COG2009	succinate dehydrogenase
H0S62_RS02370	COG2921	Belongs to the UPF0250 family
H0S62_RS02375	COG0321	lipoyl(octanoyl) transferase activity
H0S62_RS02390	COG0531	amino acid
H0S62_RS02405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0S62_RS02410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0S62_RS02410	COG1648	precorrin-2 dehydrogenase activity
H0S62_RS02425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0S62_RS02455	COG0671	phosphoesterase, PA-phosphatase related
H0S62_RS02460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0S62_RS02470	COG1538	Outer membrane efflux protein
H0S62_RS02475	COG0393	Putative heavy-metal-binding
H0S62_RS02480	COG0393	Putative heavy-metal-binding
H0S62_RS02490	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS02500	COG0525	valine-tRNA ligase activity
H0S62_RS02530	COG0583	DNA-binding transcription factor activity
H0S62_RS02535	COG0004	ammonium transporteR
H0S62_RS02545	COG0642	Histidine kinase
H0S62_RS02550	COG0745	RESPONSE REGULATOR receiver
H0S62_RS02555	COG2194	sulfuric ester hydrolase activity
H0S62_RS02575	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0S62_RS02590	COG2315	Protein conserved in bacteria
H0S62_RS02595	COG0142	geranyltranstransferase activity
H0S62_RS02600	COG2828	Protein conserved in bacteria
H0S62_RS02605	COG1113	amino acid transport
H0S62_RS02625	COG2207	Transcriptional regulator
H0S62_RS02650	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0S62_RS02660	COG0560	Phosphoserine phosphatase
H0S62_RS02670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0S62_RS02680	COG1530	ribonuclease E activity
H0S62_RS02685	COG0424	maF-like protein
H0S62_RS02690	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0S62_RS02695	COG1792	Involved in formation and maintenance of cell shape
H0S62_RS02700	COG1077	Cell shape determining protein MreB Mrl
H0S62_RS02705	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0S62_RS02715	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0S62_RS02750	COG3590	peptidase
H0S62_RS02770	COG3328	transposase activity
H0S62_RS02780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0S62_RS02785	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0S62_RS02790	COG1115	amino acid carrier protein
H0S62_RS02810	COG2814	Major facilitator Superfamily
H0S62_RS02815	COG1289	transmembrane transporter activity
H0S62_RS02825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0S62_RS02865	COG1376	ErfK ybiS ycfS ynhG family protein
H0S62_RS02870	COG2832	Protein of unknown function (DUF454)
H0S62_RS02880	COG5510	response to toxic substance
H0S62_RS02925	COG0840	transmembrane signaling receptor activity
H0S62_RS02965	COG3422	double-strand break repair
H0S62_RS02970	COG2824	Alkylphosphonate utilization operon protein PhnA
H0S62_RS02975	COG3189	MarR family transcriptional regulator
H0S62_RS02980	COG0596	Alpha beta hydrolase
H0S62_RS02985	COG0778	Nitroreductase
H0S62_RS02990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0S62_RS02995	COG1335	isochorismatase
H0S62_RS03000	COG0251	oxidation-reduction process
H0S62_RS03005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS03010	COG2233	PERMEase
H0S62_RS03025	COG0354	folic acid binding
H0S62_RS03030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0S62_RS03045	COG1902	pentaerythritol trinitrate reductase activity
H0S62_RS03050	COG4772	TonB-dependent receptor
H0S62_RS03055	COG2094	Belongs to the DNA glycosylase MPG family
H0S62_RS03085	COG2233	PERMEase
H0S62_RS03095	COG0833	amino acid
H0S62_RS03100	COG1690	Belongs to the RtcB family
H0S62_RS03110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0S62_RS03110	COG2885	chlorophyll binding
H0S62_RS03120	COG0183	Belongs to the thiolase family
H0S62_RS03140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0S62_RS03160	COG2207	Transcriptional regulator
H0S62_RS03165	COG0183	Belongs to the thiolase family
H0S62_RS03185	COG2153	protein acetylation
H0S62_RS03195	COG1272	protein, Hemolysin III
H0S62_RS03200	COG0477	Major facilitator Superfamily
H0S62_RS03215	COG0450	alkyl hydroperoxide reductase
H0S62_RS03235	COG0285	dihydrofolate synthase activity
H0S62_RS03280	COG4206	TonB-dependent receptor
H0S62_RS03285	COG2096	Adenosyltransferase
H0S62_RS03290	COG0584	glycerophosphoryl diester phosphodiesterase
H0S62_RS03305	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0S62_RS03310	COG0745	RESPONSE REGULATOR receiver
H0S62_RS03315	COG2205	protein histidine kinase activity
H0S62_RS03325	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS03330	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS03380	COG1215	transferase activity, transferring glycosyl groups
H0S62_RS03395	COG1091	dTDP-4-dehydrorhamnose reductase activity
H0S62_RS03410	COG0438	transferase activity, transferring glycosyl groups
H0S62_RS03415	COG0726	polysaccharide deacetylase
H0S62_RS03430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H0S62_RS03435	COG2205	protein histidine kinase activity
H0S62_RS03445	COG3646	Phage regulatory protein
H0S62_RS03460	COG4695	Portal protein
H0S62_RS03630	COG3646	Phage regulatory protein
H0S62_RS03710	COG1862	Preprotein translocase
H0S62_RS03730	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0S62_RS03740	COG3781	membrane
H0S62_RS03745	COG0613	PHP domain protein
H0S62_RS03755	COG2350	Protein conserved in bacteria
H0S62_RS03785	COG1607	acyl-coa hydrolase
H0S62_RS03870	COG1408	metallophosphoesterase
H0S62_RS03875	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0S62_RS03885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0S62_RS03905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0S62_RS03910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0S62_RS03925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0S62_RS03935	COG2969	positive regulation of protein catabolic process
H0S62_RS03955	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS03960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0S62_RS03975	COG1309	transcriptional regulator
H0S62_RS03985	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS04040	COG1183	phosphatidylcholine synthase activity
H0S62_RS04045	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0S62_RS04075	COG0741	lytic transglycosylase activity
H0S62_RS04075	COG0739	heme binding
H0S62_RS04075	COG1196	nuclear chromosome segregation
H0S62_RS04085	COG1702	phosphate starvation-inducible protein PhoH
H0S62_RS04130	COG1295	ribonuclease BN
H0S62_RS04135	COG0697	spore germination
H0S62_RS04140	COG2169	Transcriptional regulator
H0S62_RS04145	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0S62_RS04170	COG3293	Transposase
H0S62_RS04200	COG0557	exoribonuclease II activity
H0S62_RS04205	COG0339	signal peptide processing
H0S62_RS04210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0S62_RS04230	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0S62_RS04235	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS04390	COG0626	cystathionine gamma-synthase activity
H0S62_RS04395	COG0433	COG0433 Predicted ATPase
H0S62_RS04405	COG1017	nitric oxide dioxygenase activity
H0S62_RS04405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0S62_RS04410	COG1959	2 iron, 2 sulfur cluster binding
H0S62_RS04425	COG1301	dicarboxylic acid transport
H0S62_RS04430	COG1946	Acyl-CoA thioesterase
H0S62_RS04450	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0S62_RS04460	COG0494	nUDIX hydrolase
H0S62_RS04470	COG0598	Magnesium transport protein CorA
H0S62_RS04480	COG2854	intermembrane phospholipid transfer
H0S62_RS04490	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0S62_RS04495	COG1127	ABC transporter
H0S62_RS04505	COG0513	Belongs to the DEAD box helicase family
H0S62_RS04525	COG0408	coproporphyrinogen oxidase activity
H0S62_RS04540	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS04550	COG1983	PspC domain protein
H0S62_RS04555	COG0517	IMP dehydrogenase activity
H0S62_RS04605	COG0583	DNA-binding transcription factor activity
H0S62_RS04645	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS04655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0S62_RS04660	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0S62_RS04665	COG0833	amino acid
H0S62_RS04695	COG1192	Involved in chromosome partitioning
H0S62_RS04700	COG0628	permease
H0S62_RS04715	COG1289	transmembrane transporter activity
H0S62_RS04730	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0S62_RS04735	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0S62_RS04745	COG0277	FAD linked oxidase domain protein
H0S62_RS04750	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0S62_RS04775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0S62_RS04780	COG5380	lipid catabolic process
H0S62_RS04800	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0S62_RS04850	COG0194	GDP metabolic process
H0S62_RS04865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0S62_RS04885	COG3307	-O-antigen
H0S62_RS04900	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0S62_RS04905	COG1704	LemA family
H0S62_RS04915	COG0493	'glutamate synthase
H0S62_RS04920	COG0070	glutamate synthase
H0S62_RS04920	COG0069	glutamate synthase activity
H0S62_RS04920	COG0067	glutamate synthase
H0S62_RS04970	COG2226	methyltransferase
H0S62_RS04985	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0S62_RS04990	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0S62_RS05035	COG0833	amino acid
H0S62_RS05135	COG0488	(ABC) transporter
H0S62_RS05140	COG2873	o-acetylhomoserine
H0S62_RS05145	COG4221	oxidoreductase activity
H0S62_RS05150	COG0659	secondary active sulfate transmembrane transporter activity
H0S62_RS05160	COG0745	RESPONSE REGULATOR receiver
H0S62_RS05175	COG0427	acetyl-CoA hydrolase
H0S62_RS05205	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0S62_RS05245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0S62_RS05315	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0S62_RS05330	COG0667	Aldo Keto reductase
H0S62_RS05350	COG0583	DNA-binding transcription factor activity
H0S62_RS05355	COG2814	Major facilitator Superfamily
H0S62_RS05385	COG1335	isochorismatase
H0S62_RS05395	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS05400	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0S62_RS05410	COG1113	amino acid transport
H0S62_RS05420	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0S62_RS05435	COG2814	Major facilitator Superfamily
H0S62_RS05450	COG0351	phosphomethylpyrimidine kinase
H0S62_RS05450	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0S62_RS05450	COG0352	thiamine-phosphate diphosphorylase activity
H0S62_RS05470	COG1309	transcriptional regulator
H0S62_RS05475	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0S62_RS05480	COG3706	GGDEF domain
H0S62_RS05490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0S62_RS05500	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0S62_RS05505	COG3162	membrane
H0S62_RS05510	COG2205	protein histidine kinase activity
H0S62_RS05510	COG2198	Histidine kinase
H0S62_RS05510	COG0784	Response regulator, receiver
H0S62_RS05535	COG1522	sequence-specific DNA binding
H0S62_RS05540	COG1335	isochorismatase
H0S62_RS05545	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0S62_RS05555	COG0668	transmembrane transport
H0S62_RS05560	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0S62_RS05565	COG1519	Transferase
H0S62_RS05570	COG1902	pentaerythritol trinitrate reductase activity
H0S62_RS05590	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0S62_RS05615	COG0426	domain, Protein
H0S62_RS05615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS05620	COG4774	siderophore transport
H0S62_RS05625	COG2119	membrane
H0S62_RS05635	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0S62_RS05645	COG4942	peptidase
H0S62_RS05660	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0S62_RS05670	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0S62_RS05690	COG0189	ligase activity
H0S62_RS05715	COG0708	Exodeoxyribonuclease III
H0S62_RS05720	COG1393	Belongs to the ArsC family
H0S62_RS05735	COG3706	GGDEF domain
H0S62_RS05770	COG2351	hydroxyisourate hydrolase activity
H0S62_RS05775	COG2233	PERMEase
H0S62_RS05785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0S62_RS05795	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H0S62_RS05805	COG3150	esterase
H0S62_RS05825	COG2918	glutathione biosynthetic process
H0S62_RS05840	COG2733	membrane
H0S62_RS05845	COG0436	Aminotransferase
H0S62_RS05850	COG0534	Mate efflux family protein
H0S62_RS05900	COG0753	catalase activity
H0S62_RS05945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0S62_RS05950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0S62_RS05960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0S62_RS06015	COG0010	Belongs to the arginase family
H0S62_RS06045	COG2188	Transcriptional regulator
H0S62_RS06055	COG0523	cobalamin synthesis protein
H0S62_RS06065	COG1113	amino acid transport
H0S62_RS06075	COG0625	glutathione transferase activity
H0S62_RS06095	COG1683	Conserved Protein
H0S62_RS06100	COG0534	Mate efflux family protein
H0S62_RS06105	COG0385	Bile acid
H0S62_RS06110	COG1335	isochorismatase
H0S62_RS06115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0S62_RS06135	COG2116	formate transmembrane transporter activity
H0S62_RS06140	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0S62_RS06145	COG2133	pyrroloquinoline quinone binding
H0S62_RS06150	COG2983	Belongs to the UPF0260 family
H0S62_RS06170	COG1194	a g-specific adenine glycosylase
H0S62_RS06185	COG2818	Glycosylase
H0S62_RS06190	COG1064	alcohol dehydrogenase
H0S62_RS06195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0S62_RS06210	COG0583	DNA-binding transcription factor activity
H0S62_RS06215	COG0656	L-ascorbic acid biosynthetic process
H0S62_RS06220	COG2814	Major facilitator Superfamily
H0S62_RS06255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0S62_RS06270	COG2233	PERMEase
H0S62_RS06275	COG0583	DNA-binding transcription factor activity
H0S62_RS06310	COG0733	neurotransmitter:sodium symporter activity
H0S62_RS06325	COG3293	Transposase
H0S62_RS06365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0S62_RS06370	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0S62_RS06375	COG0596	Alpha beta hydrolase
H0S62_RS06400	COG0488	(ABC) transporter
H0S62_RS06405	COG0586	Pfam SNARE associated Golgi protein
H0S62_RS06415	COG0187	DNA topoisomerase II activity
H0S62_RS06425	COG0592	DNA-directed DNA polymerase activity
H0S62_RS06455	COG0706	membrane insertase activity
H0S62_RS06470	COG1230	cation diffusion facilitator family transporter
H0S62_RS06475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0S62_RS06490	COG0402	S-adenosylhomocysteine deaminase activity
H0S62_RS06510	COG0861	Integral membrane protein TerC family
H0S62_RS06515	COG0671	phosphoesterase, PA-phosphatase related
H0S62_RS06530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0S62_RS06545	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0S62_RS06550	COG2951	lytic endotransglycosylase activity
H0S62_RS06615	COG3328	transposase activity
H0S62_RS06630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0S62_RS06670	COG1047	Peptidyl-prolyl cis-trans
H0S62_RS06680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0S62_RS06685	COG0196	riboflavin kinase activity
H0S62_RS06695	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0S62_RS06700	COG1309	transcriptional regulator
H0S62_RS06705	COG1116	anion transmembrane transporter activity
H0S62_RS06710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0S62_RS06715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0S62_RS06720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0S62_RS06725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0S62_RS06745	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS06750	COG0546	phosphoglycolate phosphatase activity
H0S62_RS06805	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0S62_RS06810	COG0728	peptidoglycan biosynthetic process
H0S62_RS06835	COG1596	polysaccharide export
H0S62_RS06840	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0S62_RS06845	COG1086	Polysaccharide biosynthesis protein
H0S62_RS06850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0S62_RS06855	COG1083	cytidylyl-transferase
H0S62_RS06870	COG2089	acid synthase
H0S62_RS06900	COG1216	Glycosyl transferase, family 2
H0S62_RS06905	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0S62_RS06910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0S62_RS06925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0S62_RS06940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0S62_RS06950	COG2186	Transcriptional regulator
H0S62_RS06960	COG0277	FAD linked oxidase domain protein
H0S62_RS06965	COG1448	Aminotransferase
H0S62_RS06975	COG1802	Transcriptional regulator
H0S62_RS06990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0S62_RS07020	COG0564	pseudouridine synthase activity
H0S62_RS07060	COG0251	oxidation-reduction process
H0S62_RS07065	COG1113	amino acid transport
H0S62_RS07070	COG1113	amino acid transport
H0S62_RS07100	COG4115	mRNA cleavage
H0S62_RS07110	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H0S62_RS07120	COG3756	Protein conserved in bacteria
H0S62_RS07155	COG0271	Belongs to the BolA IbaG family
H0S62_RS07165	COG1192	Involved in chromosome partitioning
H0S62_RS07180	COG0586	Pfam SNARE associated Golgi protein
H0S62_RS07185	COG2259	Doxx family
H0S62_RS07190	COG4399	Belongs to the UPF0754 family
H0S62_RS07195	COG0519	Catalyzes the synthesis of GMP from XMP
H0S62_RS07195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0S62_RS07240	COG0281	malic enzyme
H0S62_RS07245	COG2837	iron assimilation
H0S62_RS07250	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS07255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0S62_RS07260	COG1121	(ABC) transporter
H0S62_RS07335	COG0697	spore germination
H0S62_RS07345	COG0758	DNA mediated transformation
H0S62_RS07380	COG1309	transcriptional regulator
H0S62_RS07415	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0S62_RS07425	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0S62_RS07460	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0S62_RS07470	COG0477	Major facilitator Superfamily
H0S62_RS07480	COG1253	flavin adenine dinucleotide binding
H0S62_RS07485	COG3012	SEC-C Motif Domain Protein
H0S62_RS07490	COG2860	membrane
H0S62_RS07495	COG0477	Major facilitator Superfamily
H0S62_RS07505	COG0318	PFAM AMP-dependent synthetase and ligase
H0S62_RS07520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0S62_RS07535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0S62_RS07540	COG0235	Class ii aldolase
H0S62_RS07545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0S62_RS07550	COG0606	chelatase, subunit chli
H0S62_RS07675	COG0606	chelatase, subunit chli
H0S62_RS07685	COG0347	Belongs to the P(II) protein family
H0S62_RS07690	COG0004	ammonium transporteR
H0S62_RS07700	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0S62_RS07700	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0S62_RS07745	COG0795	lipopolysaccharide-transporting ATPase activity
H0S62_RS07750	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0S62_RS07755	COG0793	Belongs to the peptidase S41A family
H0S62_RS07770	COG2197	response regulator
H0S62_RS07780	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0S62_RS07790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0S62_RS07795	COG4974	Belongs to the 'phage' integrase family
H0S62_RS07820	COG0772	Belongs to the SEDS family
H0S62_RS07825	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0S62_RS07830	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0S62_RS07835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0S62_RS07860	COG0697	spore germination
H0S62_RS07865	COG1538	Outer membrane efflux protein
H0S62_RS07905	COG0181	hydroxymethylbilane synthase activity
H0S62_RS07950	COG1716	ATPase activity
H0S62_RS07955	COG0546	phosphoglycolate phosphatase activity
H0S62_RS08050	COG0596	Alpha beta hydrolase
H0S62_RS08055	COG2056	Na+-H+ antiporter family
H0S62_RS08070	COG0326	Molecular chaperone. Has ATPase activity
H0S62_RS08085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0S62_RS08145	COG3328	transposase activity
H0S62_RS08155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0S62_RS08160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0S62_RS08160	COG2169	Transcriptional regulator
H0S62_RS08190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0S62_RS08200	COG0497	DNA recombination
H0S62_RS08215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0S62_RS08225	COG0237	dephospho-CoA kinase activity
H0S62_RS08275	COG0195	Participates in both transcription termination and antitermination
H0S62_RS08295	COG2212	antiporter activity
H0S62_RS08305	COG0651	ATP synthesis coupled electron transport
H0S62_RS08310	COG1006	Multisubunit Na H antiporter MnhC subunit
H0S62_RS08315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0S62_RS08315	COG2111	Na H antiporter
H0S62_RS08330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0S62_RS08335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0S62_RS08350	COG2226	methyltransferase
H0S62_RS08370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0S62_RS08375	COG1074	ATP-dependent DNA helicase activity
H0S62_RS08380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0S62_RS08400	COG0598	Magnesium transport protein CorA
H0S62_RS08405	COG0789	Transcriptional regulator
H0S62_RS08410	COG0484	heat shock protein binding
H0S62_RS08425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0S62_RS08425	COG0475	glutathione-regulated potassium exporter activity
H0S62_RS08430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0S62_RS08450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0S62_RS08460	COG4535	Mg2 and Co2 transporter CorC
H0S62_RS08465	COG0425	Belongs to the sulfur carrier protein TusA family
H0S62_RS08470	COG0644	oxidoreductase
H0S62_RS08470	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0S62_RS08480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0S62_RS08495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0S62_RS08500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0S62_RS08540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0S62_RS08555	COG0534	Mate efflux family protein
H0S62_RS08565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0S62_RS08595	COG0318	PFAM AMP-dependent synthetase and ligase
H0S62_RS08600	COG1530	ribonuclease E activity
H0S62_RS08610	COG0546	phosphoglycolate phosphatase activity
H0S62_RS08615	COG2378	regulation of single-species biofilm formation
H0S62_RS08620	COG0625	glutathione transferase activity
H0S62_RS08630	COG0583	DNA-binding transcription factor activity
H0S62_RS08685	COG0473	3-isopropylmalate dehydrogenase activity
H0S62_RS08755	COG1301	dicarboxylic acid transport
H0S62_RS08765	COG1560	Kdo2-lipid A biosynthetic process
H0S62_RS08770	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS08780	COG2900	Belongs to the SlyX family
H0S62_RS08790	COG1733	regulation of RNA biosynthetic process
H0S62_RS08815	COG0210	DNA helicase
H0S62_RS08820	COG0724	RNA recognition motif
H0S62_RS08840	COG4651	solute:proton antiporter activity
H0S62_RS08840	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0S62_RS08865	COG0788	formyltetrahydrofolate deformylase activity
H0S62_RS08980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0S62_RS08980	COG2813	Specifically methylates the guanine in position
H0S62_RS08990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0S62_RS09000	COG4774	siderophore transport
H0S62_RS09010	COG0740	serine-type endopeptidase activity
H0S62_RS09030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0S62_RS09030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0S62_RS09035	COG0857	belongs to the CobB CobQ family
H0S62_RS09035	COG0280	phosphate acetyltransferase
H0S62_RS09040	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0S62_RS09050	COG0800	Aldolase
H0S62_RS09060	COG3265	gluconokinase activity
H0S62_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS09075	COG2267	carboxylic ester hydrolase activity
H0S62_RS09090	COG0793	Belongs to the peptidase S41A family
H0S62_RS09125	COG1426	Protein conserved in bacteria
H0S62_RS09165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0S62_RS09175	COG1162	GTPase activity
H0S62_RS09180	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0S62_RS09195	COG1538	Outer membrane efflux protein
H0S62_RS09200	COG0577	efflux transmembrane transporter activity
H0S62_RS09200	COG1136	(ABC) transporter
H0S62_RS09205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0S62_RS09230	COG0028	Belongs to the TPP enzyme family
H0S62_RS09235	COG0440	acetolactate synthase activity
H0S62_RS09275	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H0S62_RS09290	COG0084	hydrolase, TatD family'
H0S62_RS09300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0S62_RS09310	COG0583	DNA-binding transcription factor activity
H0S62_RS09320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0S62_RS09325	COG2814	Major facilitator Superfamily
H0S62_RS09335	COG0697	spore germination
H0S62_RS09365	COG3622	Belongs to the hyi family
H0S62_RS09370	COG2084	Dehydrogenase
H0S62_RS09375	COG1024	Enoyl-CoA hydratase
H0S62_RS09380	COG0784	Response regulator, receiver
H0S62_RS09380	COG2205	protein histidine kinase activity
H0S62_RS09380	COG5002	protein histidine kinase activity
H0S62_RS09400	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0S62_RS09410	COG3956	TIGRFAM MazG family protein
H0S62_RS09420	COG0617	tRNA 3'-terminal CCA addition
H0S62_RS09425	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0S62_RS09445	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0S62_RS09450	COG3028	Belongs to the UPF0307 family
H0S62_RS09455	COG0318	PFAM AMP-dependent synthetase and ligase
H0S62_RS09470	COG0625	glutathione transferase activity
H0S62_RS09475	COG1238	metal cluster binding
H0S62_RS09525	COG0072	phenylalanine-tRNA ligase activity
H0S62_RS09555	COG0248	Ppx GppA phosphatase
H0S62_RS09565	COG0037	tRNA processing
H0S62_RS09605	COG1764	response to oxidative stress
H0S62_RS09610	COG1846	Transcriptional regulator
H0S62_RS09620	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0S62_RS09680	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0S62_RS09685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0S62_RS09690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0S62_RS09700	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0S62_RS09710	COG3328	transposase activity
H0S62_RS09730	COG1214	PFAM Peptidase M22, glycoprotease
H0S62_RS09745	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H0S62_RS09755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0S62_RS09760	COG0561	phosphatase activity
H0S62_RS09770	COG2132	Multicopper oxidase
H0S62_RS09775	COG3667	copper resistance
H0S62_RS09790	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0S62_RS09795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0S62_RS09800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0S62_RS09835	COG4695	Portal protein
H0S62_RS09880	COG3409	Peptidoglycan-binding domain 1 protein
H0S62_RS09880	COG0860	N-Acetylmuramoyl-L-alanine amidase
H0S62_RS10090	COG0582	viral genome integration into host DNA
H0S62_RS10105	COG1063	alcohol dehydrogenase
H0S62_RS10120	COG0583	DNA-binding transcription factor activity
H0S62_RS10130	COG0583	DNA-binding transcription factor activity
H0S62_RS10145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS10160	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0S62_RS10180	COG0745	RESPONSE REGULATOR receiver
H0S62_RS10185	COG2205	protein histidine kinase activity
H0S62_RS10195	COG3706	GGDEF domain
H0S62_RS10220	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0S62_RS10250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0S62_RS10255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0S62_RS10275	COG0583	DNA-binding transcription factor activity
H0S62_RS10295	COG0668	transmembrane transport
H0S62_RS10305	COG2081	HI0933 family
H0S62_RS10310	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0S62_RS10340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0S62_RS10340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0S62_RS10350	COG0489	protein tyrosine kinase activity
H0S62_RS10400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0S62_RS10410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0S62_RS10425	COG0730	response to heat
H0S62_RS10435	COG1196	nuclear chromosome segregation
H0S62_RS10455	COG2223	nitrite transmembrane transporter activity
H0S62_RS10460	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0S62_RS10465	COG1877	trehalose-phosphatase activity
H0S62_RS10470	COG2226	methyltransferase
H0S62_RS10470	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0S62_RS10470	COG0596	Alpha beta hydrolase
H0S62_RS10485	COG4106	trans-aconitate 2-methyltransferase activity
H0S62_RS10505	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0S62_RS10510	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H0S62_RS10515	COG0009	L-threonylcarbamoyladenylate synthase
H0S62_RS10520	COG3101	peptidyl-lysine hydroxylation
H0S62_RS10525	COG1399	metal-binding, possibly nucleic acid-binding protein
H0S62_RS10550	COG1652	LysM domain
H0S62_RS10555	COG0352	thiamine-phosphate diphosphorylase activity
H0S62_RS10555	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0S62_RS10555	COG0351	phosphomethylpyrimidine kinase
H0S62_RS10575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0S62_RS10615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0S62_RS10645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0S62_RS10660	COG0358	DNA primase activity
H0S62_RS10670	COG0564	pseudouridine synthase activity
H0S62_RS11015	COG0582	viral genome integration into host DNA
H0S62_RS11025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0S62_RS11045	COG0583	DNA-binding transcription factor activity
H0S62_RS11050	COG0473	3-isopropylmalate dehydrogenase activity
H0S62_RS11070	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS11105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0S62_RS11105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0S62_RS11165	COG0456	acetyltransferase
H0S62_RS11175	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0S62_RS11180	COG0492	ferredoxin-NADP+ reductase activity
H0S62_RS11185	COG1674	ftsk spoiiie
H0S62_RS11185	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0S62_RS11190	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS11205	COG2894	cell division
H0S62_RS11220	COG0204	Acyl-transferase
H0S62_RS11225	COG2885	chlorophyll binding
H0S62_RS11230	COG0210	DNA helicase
H0S62_RS11240	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0S62_RS11255	COG0121	glutamine amidotransferase
H0S62_RS11275	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0S62_RS11280	COG0735	belongs to the Fur family
H0S62_RS11305	COG0420	3'-5' exonuclease activity
H0S62_RS11325	COG1090	epimerase
H0S62_RS11340	COG2050	protein possibly involved in aromatic compounds catabolism
H0S62_RS11350	COG2814	Major facilitator Superfamily
H0S62_RS11355	COG0405	Gamma-glutamyltransferase
H0S62_RS11365	COG0582	viral genome integration into host DNA
H0S62_RS11445	COG0477	Major facilitator Superfamily
H0S62_RS11450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0S62_RS11475	COG0531	amino acid
H0S62_RS11480	COG2040	homocysteine
H0S62_RS11505	COG1309	transcriptional regulator
H0S62_RS11510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0S62_RS11515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0S62_RS11525	COG1607	acyl-coa hydrolase
H0S62_RS11535	COG0523	cobalamin synthesis protein
H0S62_RS11555	COG4681	YaeQ
H0S62_RS11565	COG1649	PFAM Uncharacterised BCR, COG1649
H0S62_RS11565	COG0726	polysaccharide deacetylase
H0S62_RS11570	COG1215	transferase activity, transferring glycosyl groups
H0S62_RS11580	COG1024	Enoyl-CoA hydratase
H0S62_RS11595	COG1414	Transcriptional regulator
H0S62_RS11615	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS11625	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0S62_RS11630	COG2271	Major facilitator Superfamily
H0S62_RS11640	COG2267	carboxylic ester hydrolase activity
H0S62_RS11645	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS11660	COG0028	Belongs to the TPP enzyme family
H0S62_RS11670	COG0477	Major facilitator Superfamily
H0S62_RS11675	COG0242	peptide deformylase activity
H0S62_RS11680	COG2066	Belongs to the glutaminase family
H0S62_RS11685	COG2207	Transcriptional regulator
H0S62_RS11690	COG2223	nitrite transmembrane transporter activity
H0S62_RS11705	COG0583	DNA-binding transcription factor activity
H0S62_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS11715	COG2271	Major facilitator Superfamily
H0S62_RS11720	COG3959	Transketolase, thiamine diphosphate binding domain
H0S62_RS11725	COG3958	Transketolase
H0S62_RS11735	COG0306	phosphate transporter
H0S62_RS11755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0S62_RS11800	COG4181	ATPase activity
H0S62_RS11805	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0S62_RS11835	COG0583	DNA-binding transcription factor activity
H0S62_RS11845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0S62_RS11850	COG1773	rubredoxin
H0S62_RS11900	COG2851	Citrate transporter
H0S62_RS11905	COG1253	flavin adenine dinucleotide binding
H0S62_RS11950	COG0804	urea catabolic process
H0S62_RS11960	COG0830	nickel cation binding
H0S62_RS11975	COG0742	ribosomal rna small subunit methyltransferase
H0S62_RS11980	COG0768	penicillin binding
H0S62_RS12005	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0S62_RS12010	COG2878	Part of a membrane complex involved in electron transport
H0S62_RS12015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0S62_RS12025	COG3384	dioxygenase
H0S62_RS12045	COG3328	transposase activity
H0S62_RS12060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0S62_RS12115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0S62_RS12200	COG1484	DNA-dependent DNA replication
H0S62_RS12410	COG0592	DNA-directed DNA polymerase activity
H0S62_RS12485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0S62_RS12530	COG0006	proline dipeptidase activity
H0S62_RS12535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0S62_RS12540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0S62_RS12560	COG1279	arginine transmembrane transporter activity
H0S62_RS12565	COG0583	DNA-binding transcription factor activity
H0S62_RS12605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0S62_RS12610	COG0741	lytic transglycosylase activity
H0S62_RS12610	COG1388	LysM domain
H0S62_RS12610	COG1388	LysM domain
H0S62_RS12610	COG0741	lytic transglycosylase activity
H0S62_RS12620	COG4174	ABC transporter (Permease)
H0S62_RS12625	COG4239	(ABC) transporter, permease
H0S62_RS12630	COG4172	Belongs to the ABC transporter superfamily
H0S62_RS12650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0S62_RS12660	COG2203	Gaf domain
H0S62_RS12660	COG5001	Diguanylate cyclase
H0S62_RS12660	COG4251	negative regulation of phosphorylation
H0S62_RS12660	COG3706	GGDEF domain
H0S62_RS12670	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0S62_RS12670	COG1902	pentaerythritol trinitrate reductase activity
H0S62_RS12685	COG4269	membrane
H0S62_RS12740	COG1113	amino acid transport
H0S62_RS12750	COG0531	amino acid
H0S62_RS12770	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS12825	COG2252	PERMEase
H0S62_RS12830	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0S62_RS12850	COG3038	cytochrome b561
H0S62_RS12860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0S62_RS12870	COG0527	aspartate kinase activity
H0S62_RS12880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0S62_RS12890	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0S62_RS12905	COG0667	Aldo Keto reductase
H0S62_RS12915	COG1765	OsmC-like protein
H0S62_RS12930	COG0542	response to heat
H0S62_RS12965	COG2885	chlorophyll binding
H0S62_RS12975	COG0625	glutathione transferase activity
H0S62_RS13005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0S62_RS13025	COG3634	alkyl hydroperoxide reductase activity
H0S62_RS13035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0S62_RS13045	COG0450	alkyl hydroperoxide reductase
H0S62_RS13050	COG1643	Atp-dependent helicase
H0S62_RS13065	COG2814	Major facilitator Superfamily
H0S62_RS13070	COG3135	benzoate transporter
H0S62_RS13075	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS13080	COG0543	2 iron, 2 sulfur cluster binding
H0S62_RS13080	COG0633	Ferredoxin
H0S62_RS13085	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0S62_RS13090	COG4638	Rieske (2fe-2S)
H0S62_RS13095	COG0583	DNA-binding transcription factor activity
H0S62_RS13145	COG1570	exodeoxyribonuclease VII activity
H0S62_RS13180	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS13190	COG1278	Cold shock
H0S62_RS13235	COG3328	transposase activity
H0S62_RS13245	COG2814	Major facilitator Superfamily
H0S62_RS13285	COG0517	IMP dehydrogenase activity
H0S62_RS13285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0S62_RS13290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0S62_RS13300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0S62_RS13305	COG1137	ATPase activity
H0S62_RS13310	COG1538	Outer membrane efflux protein
H0S62_RS13340	COG4122	O-methyltransferase activity
H0S62_RS13350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0S62_RS13425	COG1560	Kdo2-lipid A biosynthetic process
H0S62_RS13435	COG2814	Major facilitator Superfamily
H0S62_RS13445	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0S62_RS13450	COG1116	anion transmembrane transporter activity
H0S62_RS13455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0S62_RS13460	COG4521	taurine ABC transporter
H0S62_RS13475	COG3293	Transposase
H0S62_RS13490	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0S62_RS13545	COG0583	DNA-binding transcription factor activity
H0S62_RS13550	COG1914	H( )-stimulated, divalent metal cation uptake system
H0S62_RS13570	COG4770	biotin carboxylase activity
H0S62_RS13575	COG0038	chloride channel
H0S62_RS13605	COG1063	alcohol dehydrogenase
H0S62_RS13620	COG3293	Transposase
H0S62_RS13625	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0S62_RS13635	COG0789	Transcriptional regulator
H0S62_RS13645	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0S62_RS13665	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0S62_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS13705	COG0531	amino acid
H0S62_RS13715	COG2030	dehydratase
H0S62_RS13715	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS13720	COG3396	Phenylacetate-CoA oxygenase
H0S62_RS13725	COG3460	Phenylacetate-CoA oxygenase
H0S62_RS13730	COG3396	Phenylacetate-CoA oxygenase
H0S62_RS13735	COG2151	metal-sulfur cluster biosynthetic enzyme
H0S62_RS13740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0S62_RS13745	COG1024	Enoyl-CoA hydratase
H0S62_RS13750	COG1024	Enoyl-CoA hydratase
H0S62_RS13760	COG0183	Belongs to the thiolase family
H0S62_RS13765	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H0S62_RS13770	COG3327	negative regulation of DNA-templated transcription, initiation
H0S62_RS13780	COG2050	protein possibly involved in aromatic compounds catabolism
H0S62_RS13795	COG0406	alpha-ribazole phosphatase activity
H0S62_RS13815	COG1309	transcriptional regulator
H0S62_RS13820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0S62_RS13840	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0S62_RS13845	COG0531	amino acid
H0S62_RS13850	COG0753	catalase activity
H0S62_RS13855	COG3038	cytochrome b561
H0S62_RS13875	COG2267	carboxylic ester hydrolase activity
H0S62_RS13880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS13885	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0S62_RS13890	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS13900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0S62_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
H0S62_RS13915	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0S62_RS13920	COG0583	DNA-binding transcription factor activity
H0S62_RS13930	COG1414	Transcriptional regulator
H0S62_RS13935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0S62_RS13945	COG1840	ABC-type Fe3 transport system, periplasmic component
H0S62_RS13950	COG3842	ATPase activity
H0S62_RS13965	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0S62_RS13970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0S62_RS13975	COG2814	Major facilitator Superfamily
H0S62_RS13980	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS13995	COG1024	Enoyl-CoA hydratase
H0S62_RS14025	COG0183	Belongs to the thiolase family
H0S62_RS14030	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0S62_RS14035	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS14040	COG1024	Enoyl-CoA hydratase
H0S62_RS14045	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS14050	COG2814	Major facilitator Superfamily
H0S62_RS14055	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0S62_RS14060	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0S62_RS14080	COG2814	Major facilitator Superfamily
H0S62_RS14090	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS14105	COG0583	DNA-binding transcription factor activity
H0S62_RS14120	COG4770	biotin carboxylase activity
H0S62_RS14125	COG1024	Enoyl-CoA hydratase
H0S62_RS14130	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0S62_RS14135	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS14140	COG1309	transcriptional regulator
H0S62_RS14145	COG0318	PFAM AMP-dependent synthetase and ligase
H0S62_RS14165	COG0583	DNA-binding transcription factor activity
H0S62_RS14250	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS14270	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0S62_RS14290	COG2205	protein histidine kinase activity
H0S62_RS14290	COG0784	Response regulator, receiver
H0S62_RS14310	COG0765	amino acid transport
H0S62_RS14315	COG0765	amino acid transport
H0S62_RS14320	COG1126	abc transporter atp-binding protein
H0S62_RS14325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0S62_RS14330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0S62_RS14345	COG1280	lysine exporter protein (LysE YggA)
H0S62_RS14375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0S62_RS14380	COG1045	serine acetyltransferase
H0S62_RS14395	COG0583	DNA-binding transcription factor activity
H0S62_RS14400	COG0625	glutathione transferase activity
H0S62_RS14405	COG0625	glutathione transferase activity
H0S62_RS14410	COG0583	DNA-binding transcription factor activity
H0S62_RS14420	COG1346	cytolysis
H0S62_RS14440	COG2814	Major facilitator Superfamily
H0S62_RS14475	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H0S62_RS14480	COG3052	prosthetic group binding
H0S62_RS14500	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0S62_RS14520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0S62_RS14530	COG1294	oxidase, subunit
H0S62_RS14535	COG1271	oxidase subunit
H0S62_RS14555	COG0477	Major facilitator Superfamily
H0S62_RS14565	COG4521	taurine ABC transporter
H0S62_RS14570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H0S62_RS14575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0S62_RS14580	COG2175	clavaminate synthase activity
H0S62_RS14590	COG1953	Uracil, thiamine, allantoin
H0S62_RS14600	COG0583	DNA-binding transcription factor activity
H0S62_RS14610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H0S62_RS14625	COG0640	Transcriptional regulator
H0S62_RS14630	COG0798	PFAM Bile acid sodium symporter
H0S62_RS14635	COG0583	DNA-binding transcription factor activity
H0S62_RS14650	COG3634	alkyl hydroperoxide reductase activity
H0S62_RS14705	COG0436	Aminotransferase
H0S62_RS14715	COG0386	Belongs to the glutathione peroxidase family
H0S62_RS14755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0S62_RS14780	COG0012	GTP binding
H0S62_RS14785	COG2011	ABC-type metal ion transport system permease component
H0S62_RS14790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0S62_RS14800	COG1464	Belongs to the NlpA lipoprotein family
H0S62_RS14830	COG0765	amino acid transport
H0S62_RS14835	COG0765	amino acid transport
H0S62_RS14840	COG1126	abc transporter atp-binding protein
H0S62_RS14850	COG1522	sequence-specific DNA binding
H0S62_RS14925	COG3121	Chaperone
H0S62_RS14930	COG3539	Fimbrial protein
H0S62_RS14955	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0S62_RS14955	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0S62_RS15010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0S62_RS15020	COG2353	YceI-like domain
H0S62_RS15030	COG3698	Phosphodiester glycosidase
H0S62_RS15045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H0S62_RS15050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0S62_RS15050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0S62_RS15050	COG0506	proline dehydrogenase activity
H0S62_RS15060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0S62_RS15100	COG1132	(ABC) transporter
H0S62_RS15105	COG3122	Protein conserved in bacteria
H0S62_RS15110	COG3619	membrane
H0S62_RS15120	COG0640	Transcriptional regulator
H0S62_RS15130	COG2850	peptidyl-arginine hydroxylation
H0S62_RS15135	COG0424	maF-like protein
H0S62_RS15155	COG0191	fructose-bisphosphate aldolase activity
H0S62_RS15160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0S62_RS15175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0S62_RS15185	COG1192	Involved in chromosome partitioning
H0S62_RS15190	COG1475	DNA binding
H0S62_RS15195	COG0811	peptide transport
H0S62_RS15205	COG1132	(ABC) transporter
H0S62_RS15210	COG1663	tetraacyldisaccharide 4'-kinase activity
H0S62_RS15230	COG0084	hydrolase, TatD family'
H0S62_RS15305	COG0776	regulation of translation
H0S62_RS15325	COG3328	transposase activity
H0S62_RS15340	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0S62_RS15345	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0S62_RS15395	COG0339	signal peptide processing
H0S62_RS15405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0S62_RS15440	COG0702	epimerase
H0S62_RS15445	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0S62_RS15465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0S62_RS15495	COG0316	Belongs to the HesB IscA family
H0S62_RS15500	COG0822	iron-sulfur transferase activity
H0S62_RS15525	COG0776	regulation of translation
H0S62_RS15530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0S62_RS15535	COG2207	Transcriptional regulator
H0S62_RS15540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0S62_RS15545	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS15550	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS15565	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0S62_RS15585	COG4264	IucA IucC family
H0S62_RS15590	COG4264	IucA IucC family
H0S62_RS15600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0S62_RS15630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0S62_RS15645	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H0S62_RS15650	COG0406	alpha-ribazole phosphatase activity
H0S62_RS15665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0S62_RS15670	COG0730	response to heat
H0S62_RS15690	COG4773	Receptor
H0S62_RS15695	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0S62_RS15710	COG1131	(ABC) transporter
H0S62_RS15715	COG0842	Transport permease protein
H0S62_RS15720	COG0842	Transport permease protein
H0S62_RS15775	COG2226	methyltransferase
H0S62_RS15810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0S62_RS15845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0S62_RS15855	COG0133	tryptophan synthase activity
H0S62_RS15870	COG3706	GGDEF domain
H0S62_RS15890	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0S62_RS15895	COG0022	dehydrogenase e1 component
H0S62_RS15900	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0S62_RS15905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0S62_RS15915	COG1063	alcohol dehydrogenase
H0S62_RS15920	COG3781	membrane
H0S62_RS15930	COG3453	Protein conserved in bacteria
H0S62_RS15930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0S62_RS15940	COG0730	response to heat
H0S62_RS15955	COG2207	Transcriptional regulator
H0S62_RS15955	COG3708	Transcriptional regulator
H0S62_RS15960	COG1733	regulation of RNA biosynthetic process
H0S62_RS15965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0S62_RS15990	COG4521	taurine ABC transporter
H0S62_RS16005	COG0477	Major facilitator Superfamily
H0S62_RS16015	COG1027	Aspartate ammonia-lyase
H0S62_RS16030	COG0583	DNA-binding transcription factor activity
H0S62_RS16035	COG0583	DNA-binding transcription factor activity
H0S62_RS16070	COG2031	fatty acid transporter
H0S62_RS16085	COG0583	DNA-binding transcription factor activity
H0S62_RS16110	COG1309	transcriptional regulator
H0S62_RS16120	COG2610	gluconate transmembrane transporter activity
H0S62_RS16125	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS16130	COG2207	Transcriptional regulator
H0S62_RS16145	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS16155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS16170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0S62_RS16170	COG0543	2 iron, 2 sulfur cluster binding
H0S62_RS16175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0S62_RS16190	COG0725	ABC transporter, periplasmic molybdate-binding protein
H0S62_RS16195	COG4149	molybdate abc transporter
H0S62_RS16200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H0S62_RS16205	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS16210	COG3433	isochorismatase activity
H0S62_RS16210	COG1535	isochorismatase
H0S62_RS16300	COG0753	catalase activity
H0S62_RS16305	COG3328	transposase activity
H0S62_RS16315	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0S62_RS16340	COG3539	Fimbrial protein
H0S62_RS16380	COG1917	Cupin 2, conserved barrel domain protein
H0S62_RS16380	COG2169	Transcriptional regulator
H0S62_RS16385	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0S62_RS16390	COG3657	addiction module killer protein
H0S62_RS16400	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0S62_RS16405	COG3657	addiction module killer protein
H0S62_RS16430	COG2807	transmembrane transport
H0S62_RS16435	COG3328	transposase activity
H0S62_RS16450	COG3335	DDE superfamily endonuclease
H0S62_RS16465	COG1063	alcohol dehydrogenase
H0S62_RS16500	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H0S62_RS16515	COG1979	alcohol dehydrogenase
H0S62_RS16525	COG1902	pentaerythritol trinitrate reductase activity
H0S62_RS16535	COG1309	transcriptional regulator
H0S62_RS16540	COG2130	NADP-dependent
H0S62_RS16555	COG0697	spore germination
H0S62_RS16575	COG0071	Belongs to the small heat shock protein (HSP20) family
H0S62_RS16580	COG0542	response to heat
H0S62_RS16660	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0S62_RS16680	COG2826	transposase and inactivated derivatives, IS30 family
H0S62_RS16715	COG3328	transposase activity
H0S62_RS16745	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
H0S62_RS16755	COG2205	protein histidine kinase activity
H0S62_RS16775	COG2814	Major facilitator Superfamily
H0S62_RS16800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0S62_RS16895	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0S62_RS16915	COG1120	ATPase activity
H0S62_RS16930	COG1064	alcohol dehydrogenase
H0S62_RS16935	COG2207	Transcriptional regulator
H0S62_RS16940	COG2084	Dehydrogenase
H0S62_RS16950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0S62_RS16955	COG0583	DNA-binding transcription factor activity
H0S62_RS16965	COG0129	dihydroxy-acid dehydratase activity
H0S62_RS17030	COG0318	PFAM AMP-dependent synthetase and ligase
H0S62_RS17055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
H0S62_RS17075	COG4638	Rieske (2fe-2S)
H0S62_RS17095	COG0154	amidase activity
H0S62_RS17105	COG2814	Major facilitator Superfamily
H0S62_RS17130	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS17135	COG0583	DNA-binding transcription factor activity
H0S62_RS17140	COG1414	Transcriptional regulator
H0S62_RS17155	COG2391	methyltransferase activity
H0S62_RS17160	COG3293	Transposase
H0S62_RS17170	COG4993	Dehydrogenase
H0S62_RS17175	COG3659	wide pore channel activity
H0S62_RS17180	COG3420	alginic acid biosynthetic process
H0S62_RS17185	COG0710	3-dehydroquinate dehydratase activity
H0S62_RS17190	COG3485	protocatechuate 3,4-dioxygenase
H0S62_RS17195	COG3485	protocatechuate 3,4-dioxygenase
H0S62_RS17200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0S62_RS17205	COG2271	Major facilitator Superfamily
H0S62_RS17210	COG0596	Alpha beta hydrolase
H0S62_RS17215	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0S62_RS17220	COG0183	Belongs to the thiolase family
H0S62_RS17225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0S62_RS17230	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0S62_RS17240	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0S62_RS17250	COG2323	membrane
H0S62_RS17295	COG1902	pentaerythritol trinitrate reductase activity
H0S62_RS17295	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0S62_RS17320	COG0542	response to heat
H0S62_RS17325	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0S62_RS17365	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0S62_RS17370	COG0569	domain protein
H0S62_RS17375	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0S62_RS17395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0S62_RS17405	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0S62_RS17420	COG1294	oxidase, subunit
H0S62_RS17425	COG4890	Cyd operon protein YbgT
H0S62_RS17440	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H0S62_RS17450	COG0552	protein localization to endoplasmic reticulum
H0S62_RS17475	COG0516	GMP reductase activity
H0S62_RS17475	COG0517	IMP dehydrogenase activity
H0S62_RS17480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0S62_RS17485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0S62_RS17495	COG0583	DNA-binding transcription factor activity
H0S62_RS17500	COG0024	Methionine aminopeptidase
H0S62_RS17530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0S62_RS17530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0S62_RS17535	COG1105	Belongs to the carbohydrate kinase PfkB family
H0S62_RS17540	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0S62_RS17540	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0S62_RS17540	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H0S62_RS17565	COG3328	transposase activity
H0S62_RS17570	COG0659	secondary active sulfate transmembrane transporter activity
H0S62_RS17590	COG1113	amino acid transport
H0S62_RS17600	COG1522	sequence-specific DNA binding
H0S62_RS17625	COG1011	Hydrolase
H0S62_RS17630	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0S62_RS17640	COG2137	regulation of response to DNA damage stimulus
H0S62_RS17655	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0S62_RS17675	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0S62_RS17690	COG0575	Belongs to the CDS family
H0S62_RS17695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0S62_RS17720	COG3852	Histidine kinase
H0S62_RS17725	COG2204	response regulator
H0S62_RS17790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0S62_RS17795	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0S62_RS17815	COG0697	spore germination
H0S62_RS17820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0S62_RS17830	COG0303	'Molybdopterin
H0S62_RS17835	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0S62_RS17835	COG0315	cyclic pyranopterin monophosphate synthase activity
H0S62_RS17850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0S62_RS17855	COG0243	molybdopterin cofactor binding
H0S62_RS17865	COG0243	molybdopterin cofactor binding
H0S62_RS17870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0S62_RS17875	COG2146	nitrite reductase [NAD(P)H] activity
H0S62_RS17875	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0S62_RS17885	COG0745	RESPONSE REGULATOR receiver
H0S62_RS17890	COG1116	anion transmembrane transporter activity
H0S62_RS17890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0S62_RS17915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0S62_RS17925	COG0511	ligase activity, forming carbon-carbon bonds
H0S62_RS17940	COG2814	Major facilitator Superfamily
H0S62_RS17970	COG0069	glutamate synthase activity
H0S62_RS17990	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0S62_RS18000	COG1454	alcohol dehydrogenase
H0S62_RS18005	COG0824	Thioesterase
H0S62_RS18015	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0S62_RS18035	COG2030	dehydratase
H0S62_RS18045	COG0183	Belongs to the thiolase family
H0S62_RS18055	COG0583	DNA-binding transcription factor activity
H0S62_RS18060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0S62_RS18070	COG1522	sequence-specific DNA binding
H0S62_RS18075	COG3135	benzoate transporter
H0S62_RS18110	COG0589	response to stress
H0S62_RS18115	COG0488	(ABC) transporter
H0S62_RS18135	COG4773	Receptor
H0S62_RS18150	COG3328	transposase activity
H0S62_RS18175	COG0668	transmembrane transport
H0S62_RS18190	COG1309	transcriptional regulator
H0S62_RS18210	COG1605	Chorismate mutase
H0S62_RS18230	COG0308	aminopeptidase N
H0S62_RS18250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0S62_RS18260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0S62_RS18265	COG1454	alcohol dehydrogenase
H0S62_RS18285	COG0531	amino acid
H0S62_RS18290	COG4303	Ethanolamine ammonia lyase large subunit
H0S62_RS18295	COG4302	ethanolamine ammonia-lyase activity
H0S62_RS18300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0S62_RS18300	COG0519	Catalyzes the synthesis of GMP from XMP
H0S62_RS18305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0S62_RS18315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0S62_RS18330	COG0697	spore germination
H0S62_RS18335	COG1923	regulation of RNA biosynthetic process
H0S62_RS18345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0S62_RS18350	COG0802	atpase or kinase
H0S62_RS18370	COG1187	pseudouridine synthase activity
H0S62_RS18385	COG0583	DNA-binding transcription factor activity
H0S62_RS18400	COG2814	Major facilitator Superfamily
H0S62_RS18405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0S62_RS18435	COG0729	surface antigen
H0S62_RS18455	COG0174	glutamine synthetase
H0S62_RS18460	COG0745	RESPONSE REGULATOR receiver
H0S62_RS18465	COG2205	protein histidine kinase activity
H0S62_RS18475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0S62_RS18480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0S62_RS18505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0S62_RS18510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0S62_RS18515	COG1960	acyl-CoA dehydrogenase activity
H0S62_RS18530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0S62_RS18535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0S62_RS18550	COG3328	transposase activity
H0S62_RS18580	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0S62_RS18585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0S62_RS18595	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0S62_RS18620	COG0305	Participates in initiation and elongation during chromosome replication
H0S62_RS18625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0S62_RS18635	COG1305	Transglutaminase-like
H0S62_RS18645	COG2308	Evidence 4 Homologs of previously reported genes of
H0S62_RS18675	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0S62_RS18680	COG0138	bifunctional purine biosynthesis protein purh
H0S62_RS18685	COG0151	Belongs to the GarS family
H0S62_RS18690	COG1464	Belongs to the NlpA lipoprotein family
H0S62_RS18695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0S62_RS18700	COG2011	ABC-type metal ion transport system permease component
H0S62_RS18705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0S62_RS18715	COG1301	dicarboxylic acid transport
H0S62_RS18745	COG1794	racemase activity, acting on amino acids and derivatives
H0S62_RS18760	COG3008	intermembrane lipid transfer
H0S62_RS18760	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0S62_RS18765	COG2995	paraquat-inducible protein a
H0S62_RS18795	COG0477	Major facilitator Superfamily
H0S62_RS18880	COG2186	Transcriptional regulator
H0S62_RS18890	COG0786	glutamate:sodium symporter activity
H0S62_RS18895	COG3243	poly(R)-hydroxyalkanoic acid synthase
H0S62_RS18980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0S62_RS19000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0S62_RS19100	COG0515	serine threonine protein kinase
H0S62_RS19105	COG2116	formate transmembrane transporter activity
H0S62_RS19110	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
H0S62_RS19170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0S62_RS19260	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H0S62_RS19260	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0S62_RS19315	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0S62_RS19315	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H0S62_RS19330	COG0587	DNA-directed DNA polymerase activity
H0S62_RS19385	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0S62_RS19445	COG0358	DNA primase activity
H0S62_RS19570	COG3706	GGDEF domain
H0S62_RS19660	COG2337	Toxic component of a toxin-antitoxin (TA) module
H0S62_RS19665	COG2336	PFAM SpoVT AbrB