locus-tag	class	description
H0N27_RS00010	COG0592	DNA-directed DNA polymerase activity
H0N27_RS00020	COG0187	DNA topoisomerase II activity
H0N27_RS00030	COG0586	Pfam SNARE associated Golgi protein
H0N27_RS00035	COG0488	(ABC) transporter
H0N27_RS00060	COG0596	Alpha beta hydrolase
H0N27_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0N27_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0N27_RS00115	COG0733	neurotransmitter:sodium symporter activity
H0N27_RS00150	COG0583	DNA-binding transcription factor activity
H0N27_RS00155	COG2233	PERMEase
H0N27_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS00205	COG2814	Major facilitator Superfamily
H0N27_RS00210	COG0656	L-ascorbic acid biosynthetic process
H0N27_RS00215	COG0583	DNA-binding transcription factor activity
H0N27_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N27_RS00235	COG1064	alcohol dehydrogenase
H0N27_RS00240	COG2818	Glycosylase
H0N27_RS00255	COG1194	a g-specific adenine glycosylase
H0N27_RS00275	COG2983	Belongs to the UPF0260 family
H0N27_RS00280	COG2133	pyrroloquinoline quinone binding
H0N27_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0N27_RS00290	COG2116	formate transmembrane transporter activity
H0N27_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N27_RS00315	COG1335	isochorismatase
H0N27_RS00320	COG0385	Bile acid
H0N27_RS00325	COG0534	Mate efflux family protein
H0N27_RS00330	COG1683	Conserved Protein
H0N27_RS00350	COG0625	glutathione transferase activity
H0N27_RS00360	COG1113	amino acid transport
H0N27_RS00370	COG0523	cobalamin synthesis protein
H0N27_RS00380	COG2188	Transcriptional regulator
H0N27_RS00410	COG0010	Belongs to the arginase family
H0N27_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0N27_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0N27_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0N27_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0N27_RS00490	COG0753	catalase activity
H0N27_RS00540	COG0534	Mate efflux family protein
H0N27_RS00545	COG0436	Aminotransferase
H0N27_RS00550	COG2733	membrane
H0N27_RS00565	COG2918	glutathione biosynthetic process
H0N27_RS00580	COG1388	LysM domain
H0N27_RS00580	COG5632	N-Acetylmuramoyl-L-alanine amidase
H0N27_RS00580	COG3409	Peptidoglycan-binding domain 1 protein
H0N27_RS00610	COG3150	esterase
H0N27_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS00625	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H0N27_RS00635	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N27_RS00645	COG2233	PERMEase
H0N27_RS00650	COG2351	hydroxyisourate hydrolase activity
H0N27_RS00685	COG3706	GGDEF domain
H0N27_RS00700	COG1393	Belongs to the ArsC family
H0N27_RS00705	COG0708	Exodeoxyribonuclease III
H0N27_RS00730	COG0189	ligase activity
H0N27_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0N27_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0N27_RS00775	COG4942	peptidase
H0N27_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0N27_RS00795	COG2119	membrane
H0N27_RS00800	COG4774	siderophore transport
H0N27_RS00805	COG0426	domain, Protein
H0N27_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0N27_RS00850	COG1902	pentaerythritol trinitrate reductase activity
H0N27_RS00855	COG1519	Transferase
H0N27_RS00865	COG0668	transmembrane transport
H0N27_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N27_RS00880	COG1335	isochorismatase
H0N27_RS00885	COG1522	sequence-specific DNA binding
H0N27_RS00910	COG0784	Response regulator, receiver
H0N27_RS00910	COG2198	Histidine kinase
H0N27_RS00910	COG2205	protein histidine kinase activity
H0N27_RS00915	COG3162	membrane
H0N27_RS00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0N27_RS00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N27_RS00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0N27_RS00950	COG1309	transcriptional regulator
H0N27_RS00970	COG0352	thiamine-phosphate diphosphorylase activity
H0N27_RS00970	COG0351	phosphomethylpyrimidine kinase
H0N27_RS00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0N27_RS00980	COG2814	Major facilitator Superfamily
H0N27_RS00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0N27_RS01005	COG1113	amino acid transport
H0N27_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0N27_RS01020	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS01030	COG1335	isochorismatase
H0N27_RS01060	COG2814	Major facilitator Superfamily
H0N27_RS01065	COG0583	DNA-binding transcription factor activity
H0N27_RS01085	COG0667	Aldo Keto reductase
H0N27_RS01115	COG1733	regulation of RNA biosynthetic process
H0N27_RS01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0N27_RS01210	COG1132	(ABC) transporter
H0N27_RS01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0N27_RS01260	COG0427	acetyl-CoA hydrolase
H0N27_RS01285	COG0659	secondary active sulfate transmembrane transporter activity
H0N27_RS01290	COG4221	oxidoreductase activity
H0N27_RS01295	COG2873	o-acetylhomoserine
H0N27_RS01300	COG0488	(ABC) transporter
H0N27_RS01365	COG0833	amino acid
H0N27_RS01410	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0N27_RS01415	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0N27_RS01430	COG2226	methyltransferase
H0N27_RS01480	COG0067	glutamate synthase
H0N27_RS01480	COG0069	glutamate synthase activity
H0N27_RS01480	COG0070	glutamate synthase
H0N27_RS01485	COG0493	'glutamate synthase
H0N27_RS01495	COG1704	LemA family
H0N27_RS01500	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0N27_RS01515	COG3307	-O-antigen
H0N27_RS01535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0N27_RS01550	COG0194	GDP metabolic process
H0N27_RS01600	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0N27_RS01620	COG5380	lipid catabolic process
H0N27_RS01625	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0N27_RS01650	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0N27_RS01655	COG0277	FAD linked oxidase domain protein
H0N27_RS01665	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0N27_RS01670	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS01685	COG1289	transmembrane transporter activity
H0N27_RS01695	COG0628	permease
H0N27_RS01700	COG1192	Involved in chromosome partitioning
H0N27_RS01730	COG0833	amino acid
H0N27_RS01735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0N27_RS01740	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0N27_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS01790	COG0583	DNA-binding transcription factor activity
H0N27_RS01810	COG0752	glycyl-tRNA synthetase alpha subunit
H0N27_RS01830	COG0517	IMP dehydrogenase activity
H0N27_RS01835	COG1983	PspC domain protein
H0N27_RS01845	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS01860	COG0408	coproporphyrinogen oxidase activity
H0N27_RS01880	COG0513	Belongs to the DEAD box helicase family
H0N27_RS01890	COG1127	ABC transporter
H0N27_RS01895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0N27_RS01905	COG2854	intermembrane phospholipid transfer
H0N27_RS01915	COG0598	Magnesium transport protein CorA
H0N27_RS01925	COG0494	nUDIX hydrolase
H0N27_RS01930	COG1040	competence protein
H0N27_RS01935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0N27_RS01955	COG1946	Acyl-CoA thioesterase
H0N27_RS01960	COG1301	dicarboxylic acid transport
H0N27_RS01975	COG1959	2 iron, 2 sulfur cluster binding
H0N27_RS01980	COG1017	nitric oxide dioxygenase activity
H0N27_RS01980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N27_RS01990	COG0433	COG0433 Predicted ATPase
H0N27_RS01995	COG0626	cystathionine gamma-synthase activity
H0N27_RS02150	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS02155	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0N27_RS02185	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0N27_RS02190	COG0339	signal peptide processing
H0N27_RS02195	COG0557	exoribonuclease II activity
H0N27_RS02240	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0N27_RS02245	COG2169	Transcriptional regulator
H0N27_RS02250	COG0697	spore germination
H0N27_RS02255	COG1295	ribonuclease BN
H0N27_RS02290	COG1702	phosphate starvation-inducible protein PhoH
H0N27_RS02300	COG0739	heme binding
H0N27_RS02300	COG1196	nuclear chromosome segregation
H0N27_RS02300	COG0741	lytic transglycosylase activity
H0N27_RS02330	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0N27_RS02335	COG1183	phosphatidylcholine synthase activity
H0N27_RS02380	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS02385	COG1309	transcriptional regulator
H0N27_RS02400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0N27_RS02405	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS02425	COG2969	positive regulation of protein catabolic process
H0N27_RS02435	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0N27_RS02445	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0N27_RS02450	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0N27_RS02455	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0N27_RS02475	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0N27_RS02485	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0N27_RS02490	COG1408	metallophosphoesterase
H0N27_RS02500	COG2199	diguanylate cyclase activity
H0N27_RS02560	COG1607	acyl-coa hydrolase
H0N27_RS02590	COG2350	Protein conserved in bacteria
H0N27_RS02600	COG0613	PHP domain protein
H0N27_RS02605	COG3781	membrane
H0N27_RS02615	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0N27_RS02620	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0N27_RS02630	COG1862	Preprotein translocase
H0N27_RS02660	COG2205	protein histidine kinase activity
H0N27_RS02665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H0N27_RS02685	COG0726	polysaccharide deacetylase
H0N27_RS02690	COG0463	Glycosyl transferase, family 2
H0N27_RS02695	COG0438	transferase activity, transferring glycosyl groups
H0N27_RS02760	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS02765	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS02775	COG2205	protein histidine kinase activity
H0N27_RS02780	COG0745	RESPONSE REGULATOR receiver
H0N27_RS02785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0N27_RS02805	COG2096	Adenosyltransferase
H0N27_RS02810	COG4206	TonB-dependent receptor
H0N27_RS02855	COG0285	dihydrofolate synthase activity
H0N27_RS02875	COG0450	alkyl hydroperoxide reductase
H0N27_RS02890	COG0477	Major facilitator Superfamily
H0N27_RS02895	COG1272	protein, Hemolysin III
H0N27_RS02925	COG0183	Belongs to the thiolase family
H0N27_RS02930	COG2207	Transcriptional regulator
H0N27_RS02950	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N27_RS02970	COG0183	Belongs to the thiolase family
H0N27_RS02980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0N27_RS02980	COG2885	chlorophyll binding
H0N27_RS02990	COG1690	Belongs to the RtcB family
H0N27_RS02995	COG0833	amino acid
H0N27_RS03005	COG2233	PERMEase
H0N27_RS03010	COG1217	gtp-binding protein TYPA
H0N27_RS03035	COG2094	Belongs to the DNA glycosylase MPG family
H0N27_RS03040	COG4772	TonB-dependent receptor
H0N27_RS03045	COG1902	pentaerythritol trinitrate reductase activity
H0N27_RS03060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N27_RS03065	COG0354	folic acid binding
H0N27_RS03075	COG3189	MarR family transcriptional regulator
H0N27_RS03080	COG2824	Alkylphosphonate utilization operon protein PhnA
H0N27_RS03085	COG3422	double-strand break repair
H0N27_RS03125	COG0840	transmembrane signaling receptor activity
H0N27_RS03145	COG5510	response to toxic substance
H0N27_RS03155	COG2832	Protein of unknown function (DUF454)
H0N27_RS03160	COG1376	ErfK ybiS ycfS ynhG family protein
H0N27_RS03200	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0N27_RS03210	COG1289	transmembrane transporter activity
H0N27_RS03215	COG2814	Major facilitator Superfamily
H0N27_RS03235	COG1115	amino acid carrier protein
H0N27_RS03240	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0N27_RS03245	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0N27_RS03250	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H0N27_RS03255	COG3590	peptidase
H0N27_RS03295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0N27_RS03305	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0N27_RS03310	COG1077	Cell shape determining protein MreB Mrl
H0N27_RS03315	COG1792	Involved in formation and maintenance of cell shape
H0N27_RS03320	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0N27_RS03325	COG0424	maF-like protein
H0N27_RS03330	COG1530	ribonuclease E activity
H0N27_RS03340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N27_RS03350	COG0560	Phosphoserine phosphatase
H0N27_RS03360	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS03385	COG2207	Transcriptional regulator
H0N27_RS03415	COG1113	amino acid transport
H0N27_RS03420	COG2828	Protein conserved in bacteria
H0N27_RS03425	COG0142	geranyltranstransferase activity
H0N27_RS03430	COG2315	Protein conserved in bacteria
H0N27_RS03445	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0N27_RS03465	COG2194	sulfuric ester hydrolase activity
H0N27_RS03470	COG0745	RESPONSE REGULATOR receiver
H0N27_RS03475	COG0642	Histidine kinase
H0N27_RS03485	COG0004	ammonium transporteR
H0N27_RS03490	COG0583	DNA-binding transcription factor activity
H0N27_RS03515	COG0525	valine-tRNA ligase activity
H0N27_RS03525	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS03535	COG0393	Putative heavy-metal-binding
H0N27_RS03540	COG0393	Putative heavy-metal-binding
H0N27_RS03545	COG1538	Outer membrane efflux protein
H0N27_RS03555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS03560	COG0671	phosphoesterase, PA-phosphatase related
H0N27_RS03590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0N27_RS03605	COG1648	precorrin-2 dehydrogenase activity
H0N27_RS03605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0N27_RS03610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0N27_RS03615	COG1733	regulation of RNA biosynthetic process
H0N27_RS03625	COG0531	amino acid
H0N27_RS03640	COG0321	lipoyl(octanoyl) transferase activity
H0N27_RS03645	COG2921	Belongs to the UPF0250 family
H0N27_RS03680	COG2009	succinate dehydrogenase
H0N27_RS03685	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0N27_RS03690	COG1053	succinate dehydrogenase
H0N27_RS03695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0N27_RS03720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N27_RS03740	COG2354	Protein conserved in bacteria
H0N27_RS03745	COG2321	neutral zinc metallopeptidase
H0N27_RS03765	COG2843	Capsule synthesis protein
H0N27_RS03780	COG0589	response to stress
H0N27_RS03800	COG0505	Belongs to the CarA family
H0N27_RS03825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0N27_RS03830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0N27_RS03870	COG2264	protein methyltransferase activity
H0N27_RS03880	COG0477	Major facilitator Superfamily
H0N27_RS03885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0N27_RS03900	COG1597	lipid kinase activity
H0N27_RS03905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0N27_RS03925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N27_RS03930	COG0584	glycerophosphoryl diester phosphodiesterase
H0N27_RS03950	COG0741	lytic transglycosylase activity
H0N27_RS03970	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0N27_RS03985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N27_RS04015	COG0778	Nitroreductase
H0N27_RS04030	COG1929	Belongs to the glycerate kinase type-1 family
H0N27_RS04035	COG0243	molybdopterin cofactor binding
H0N27_RS04040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0N27_RS04045	COG3339	Conserved Protein
H0N27_RS04055	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H0N27_RS04070	COG1113	amino acid transport
H0N27_RS04080	COG0019	diaminopimelate decarboxylase activity
H0N27_RS04090	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS04095	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0N27_RS04125	COG0463	Glycosyl transferase, family 2
H0N27_RS04145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS04180	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0N27_RS04185	COG1136	(ABC) transporter
H0N27_RS04190	COG2333	competence protein COMEC
H0N27_RS04190	COG0658	competence protein
H0N27_RS04200	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0N27_RS04200	COG0616	signal peptide processing
H0N27_RS04205	COG0596	Alpha beta hydrolase
H0N27_RS04210	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0N27_RS04220	COG0628	permease
H0N27_RS04255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0N27_RS04275	COG0823	Involved in the tonB-independent uptake of proteins
H0N27_RS04295	COG0824	Thioesterase
H0N27_RS04300	COG1473	amidohydrolase
H0N27_RS04320	COG0047	phosphoribosylformylglycinamidine synthase activity
H0N27_RS04320	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0N27_RS04325	COG2814	Major facilitator Superfamily
H0N27_RS04335	COG1024	Enoyl-CoA hydratase
H0N27_RS04340	COG1051	belongs to the nudix hydrolase family
H0N27_RS04340	COG1056	cytidyltransferase-related domain
H0N27_RS04350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0N27_RS04365	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0N27_RS04380	COG4625	pathogenesis
H0N27_RS04385	COG0583	DNA-binding transcription factor activity
H0N27_RS04390	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0N27_RS04395	COG4208	sulfate ABC transporter
H0N27_RS04400	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0N27_RS04410	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0N27_RS04415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0N27_RS04420	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0N27_RS04440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0N27_RS04455	COG0681	Belongs to the peptidase S26 family
H0N27_RS04470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0N27_RS04480	COG1381	Involved in DNA repair and RecF pathway recombination
H0N27_RS04485	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0N27_RS04495	COG4221	oxidoreductase activity
H0N27_RS04525	COG0443	Heat shock 70 kDa protein
H0N27_RS04535	COG0436	Aminotransferase
H0N27_RS04555	COG0556	nucleotide-excision repair
H0N27_RS04610	COG2070	2-Nitropropane dioxygenase
H0N27_RS04640	COG1215	transferase activity, transferring glycosyl groups
H0N27_RS04655	COG0415	Belongs to the DNA photolyase family
H0N27_RS04665	COG1252	NADH dehydrogenase
H0N27_RS04670	COG1686	Belongs to the peptidase S11 family
H0N27_RS04685	COG1187	pseudouridine synthase activity
H0N27_RS04710	COG0477	Major facilitator Superfamily
H0N27_RS04715	COG0583	DNA-binding transcription factor activity
H0N27_RS04720	COG1823	symporter activity
H0N27_RS04730	COG0612	Peptidase, M16
H0N27_RS04755	COG0352	thiamine-phosphate diphosphorylase activity
H0N27_RS04790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N27_RS04800	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS04815	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0N27_RS04820	COG0076	glutamate decarboxylase activity
H0N27_RS04830	COG1522	sequence-specific DNA binding
H0N27_RS04835	COG3961	Belongs to the TPP enzyme family
H0N27_RS04840	COG1113	amino acid transport
H0N27_RS04845	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0N27_RS04850	COG0573	inorganic phosphate transmembrane transporter activity
H0N27_RS04860	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0N27_RS04865	COG0616	signal peptide processing
H0N27_RS04900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0N27_RS04905	COG1686	Belongs to the peptidase S11 family
H0N27_RS04930	COG0583	DNA-binding transcription factor activity
H0N27_RS04935	COG1067	ATP-dependent peptidase activity
H0N27_RS04960	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0N27_RS04980	COG1966	Carbon starvation protein
H0N27_RS04985	COG2879	small protein
H0N27_RS04995	COG0583	DNA-binding transcription factor activity
H0N27_RS05000	COG0006	proline dipeptidase activity
H0N27_RS05005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N27_RS05010	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N27_RS05020	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS05025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N27_RS05030	COG0723	plastoquinol--plastocyanin reductase activity
H0N27_RS05030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0N27_RS05075	COG1741	Belongs to the pirin family
H0N27_RS05085	COG2964	Protein conserved in bacteria
H0N27_RS05100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N27_RS05105	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0N27_RS05110	COG4605	iron ion homeostasis
H0N27_RS05115	COG4604	ABC transporter, ATP-binding protein
H0N27_RS05120	COG4607	ABC-type enterochelin transport system periplasmic component
H0N27_RS05125	COG4774	siderophore transport
H0N27_RS05135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0N27_RS05140	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0N27_RS05145	COG1535	isochorismatase
H0N27_RS05145	COG3433	isochorismatase activity
H0N27_RS05155	COG1132	(ABC) transporter
H0N27_RS05160	COG1132	(ABC) transporter
H0N27_RS05165	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0N27_RS05190	COG3739	integral membrane protein
H0N27_RS05210	COG0302	gtp cyclohydrolase
H0N27_RS05220	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0N27_RS05250	COG0308	aminopeptidase N
H0N27_RS05255	COG0512	Glutamine amidotransferase of anthranilate synthase
H0N27_RS05270	COG0174	glutamine synthetase
H0N27_RS05280	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0N27_RS05315	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0N27_RS05320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0N27_RS05325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0N27_RS05345	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0N27_RS05350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0N27_RS05355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0N27_RS05370	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS05375	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0N27_RS05380	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N27_RS05390	COG2223	nitrite transmembrane transporter activity
H0N27_RS05400	COG0024	Methionine aminopeptidase
H0N27_RS05405	COG0052	Belongs to the universal ribosomal protein uS2 family
H0N27_RS05420	COG2207	Transcriptional regulator
H0N27_RS05445	COG2951	lytic endotransglycosylase activity
H0N27_RS05450	COG0772	Belongs to the SEDS family
H0N27_RS05465	COG0842	Transport permease protein
H0N27_RS05470	COG1131	(ABC) transporter
H0N27_RS05480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H0N27_RS05480	COG2755	lipolytic protein G-D-S-L family
H0N27_RS05550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS05565	COG4215	(ABC) transporter
H0N27_RS05570	COG4160	amino acid transport
H0N27_RS05575	COG4598	ABC transporter
H0N27_RS05585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N27_RS05590	COG0826	peptidase U32
H0N27_RS05595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N27_RS05610	COG1720	tRNA m6t6A37 methyltransferase activity
H0N27_RS05620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0N27_RS05625	COG3111	PFAM Bacterial OB fold (BOF) protein
H0N27_RS05635	COG0642	Histidine kinase
H0N27_RS05645	COG0494	nUDIX hydrolase
H0N27_RS05655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0N27_RS05660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0N27_RS05665	COG3139	Protein of unknown function (DUF1315)
H0N27_RS05670	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0N27_RS05675	COG1301	dicarboxylic acid transport
H0N27_RS05680	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS05685	COG2819	hydrolase of the alpha beta superfamily
H0N27_RS05695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0N27_RS05705	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0N27_RS05710	COG1234	tRNA 3'-trailer cleavage
H0N27_RS05740	COG2363	Small membrane protein
H0N27_RS05760	COG0513	Belongs to the DEAD box helicase family
H0N27_RS05770	COG0778	Nitroreductase
H0N27_RS05800	COG1286	toxin biosynthetic process
H0N27_RS05825	COG4783	chaperone-mediated protein folding
H0N27_RS05830	COG1610	YqeY-like protein
H0N27_RS05930	COG3111	PFAM Bacterial OB fold (BOF) protein
H0N27_RS05955	COG3243	poly(R)-hydroxyalkanoic acid synthase
H0N27_RS05960	COG0786	glutamate:sodium symporter activity
H0N27_RS05970	COG2186	Transcriptional regulator
H0N27_RS06020	COG0477	Major facilitator Superfamily
H0N27_RS06045	COG2995	paraquat-inducible protein a
H0N27_RS06050	COG3008	intermembrane lipid transfer
H0N27_RS06050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0N27_RS06065	COG0492	ferredoxin-NADP+ reductase activity
H0N27_RS06065	COG3118	belongs to the thioredoxin family
H0N27_RS06070	COG1794	racemase activity, acting on amino acids and derivatives
H0N27_RS06100	COG1301	dicarboxylic acid transport
H0N27_RS06110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N27_RS06115	COG2011	ABC-type metal ion transport system permease component
H0N27_RS06120	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0N27_RS06125	COG1464	Belongs to the NlpA lipoprotein family
H0N27_RS06130	COG0151	Belongs to the GarS family
H0N27_RS06135	COG0138	bifunctional purine biosynthesis protein purh
H0N27_RS06140	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0N27_RS06170	COG2308	Evidence 4 Homologs of previously reported genes of
H0N27_RS06180	COG1305	Transglutaminase-like
H0N27_RS06190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0N27_RS06195	COG0305	Participates in initiation and elongation during chromosome replication
H0N27_RS06220	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0N27_RS06230	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0N27_RS06235	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0N27_RS06260	COG1649	PFAM Uncharacterised BCR, COG1649
H0N27_RS06260	COG0726	polysaccharide deacetylase
H0N27_RS06265	COG1215	transferase activity, transferring glycosyl groups
H0N27_RS06270	COG3658	cytochrome
H0N27_RS06280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0N27_RS06295	COG0583	DNA-binding transcription factor activity
H0N27_RS06325	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS06330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N27_RS06335	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS06360	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0N27_RS06365	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0N27_RS06375	COG2205	protein histidine kinase activity
H0N27_RS06380	COG0745	RESPONSE REGULATOR receiver
H0N27_RS06385	COG0174	glutamine synthetase
H0N27_RS06405	COG0729	surface antigen
H0N27_RS06430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0N27_RS06435	COG2814	Major facilitator Superfamily
H0N27_RS06545	COG2369	cell adhesion
H0N27_RS06550	COG4383	Mu-like prophage protein gp29
H0N27_RS06565	COG4373	Mu-like prophage FluMu protein gp28
H0N27_RS06635	COG3267	Type II secretory pathway component ExeA
H0N27_RS06635	COG3409	Peptidoglycan-binding domain 1 protein
H0N27_RS06715	COG0583	DNA-binding transcription factor activity
H0N27_RS06730	COG1187	pseudouridine synthase activity
H0N27_RS06750	COG0802	atpase or kinase
H0N27_RS06755	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0N27_RS06765	COG1923	regulation of RNA biosynthetic process
H0N27_RS06770	COG0697	spore germination
H0N27_RS06785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0N27_RS06795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0N27_RS06800	COG0519	Catalyzes the synthesis of GMP from XMP
H0N27_RS06800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0N27_RS06805	COG4302	ethanolamine ammonia-lyase activity
H0N27_RS06810	COG4303	Ethanolamine ammonia lyase large subunit
H0N27_RS06815	COG0531	amino acid
H0N27_RS06835	COG1454	alcohol dehydrogenase
H0N27_RS06840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0N27_RS06850	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0N27_RS06870	COG0308	aminopeptidase N
H0N27_RS06910	COG1605	Chorismate mutase
H0N27_RS06925	COG1309	transcriptional regulator
H0N27_RS06935	COG0668	transmembrane transport
H0N27_RS06965	COG4773	Receptor
H0N27_RS06985	COG0488	(ABC) transporter
H0N27_RS06990	COG0589	response to stress
H0N27_RS07015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H0N27_RS07025	COG3135	benzoate transporter
H0N27_RS07030	COG1522	sequence-specific DNA binding
H0N27_RS07040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0N27_RS07045	COG0583	DNA-binding transcription factor activity
H0N27_RS07055	COG0183	Belongs to the thiolase family
H0N27_RS07065	COG2030	dehydratase
H0N27_RS07070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0N27_RS07085	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0N27_RS07095	COG0824	Thioesterase
H0N27_RS07100	COG1454	alcohol dehydrogenase
H0N27_RS07110	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0N27_RS07130	COG0069	glutamate synthase activity
H0N27_RS07150	COG2814	Major facilitator Superfamily
H0N27_RS07165	COG0511	ligase activity, forming carbon-carbon bonds
H0N27_RS07185	COG1116	anion transmembrane transporter activity
H0N27_RS07185	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N27_RS07190	COG0745	RESPONSE REGULATOR receiver
H0N27_RS07200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N27_RS07200	COG2146	nitrite reductase [NAD(P)H] activity
H0N27_RS07205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N27_RS07210	COG0243	molybdopterin cofactor binding
H0N27_RS07220	COG0243	molybdopterin cofactor binding
H0N27_RS07225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0N27_RS07240	COG0315	cyclic pyranopterin monophosphate synthase activity
H0N27_RS07240	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0N27_RS07245	COG0303	'Molybdopterin
H0N27_RS07255	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N27_RS07260	COG0697	spore germination
H0N27_RS07280	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0N27_RS07285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0N27_RS07340	COG2204	response regulator
H0N27_RS07345	COG3852	Histidine kinase
H0N27_RS07365	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0N27_RS07370	COG0575	Belongs to the CDS family
H0N27_RS07405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0N27_RS07420	COG2137	regulation of response to DNA damage stimulus
H0N27_RS07430	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0N27_RS07435	COG1011	Hydrolase
H0N27_RS07460	COG1522	sequence-specific DNA binding
H0N27_RS07470	COG1113	amino acid transport
H0N27_RS07485	COG0659	secondary active sulfate transmembrane transporter activity
H0N27_RS07490	COG2135	peptidase activity
H0N27_RS07505	COG3300	MHYT domain
H0N27_RS07505	COG5001	Diguanylate cyclase
H0N27_RS07520	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H0N27_RS07520	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0N27_RS07520	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0N27_RS07525	COG1105	Belongs to the carbohydrate kinase PfkB family
H0N27_RS07530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0N27_RS07530	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0N27_RS07560	COG0024	Methionine aminopeptidase
H0N27_RS07565	COG0583	DNA-binding transcription factor activity
H0N27_RS07575	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0N27_RS07580	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0N27_RS07585	COG0517	IMP dehydrogenase activity
H0N27_RS07585	COG0516	GMP reductase activity
H0N27_RS07610	COG0552	protein localization to endoplasmic reticulum
H0N27_RS07620	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H0N27_RS07630	COG4890	Cyd operon protein YbgT
H0N27_RS07635	COG1294	oxidase, subunit
H0N27_RS07650	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0N27_RS07660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0N27_RS07665	COG4774	siderophore transport
H0N27_RS07680	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0N27_RS07685	COG0569	domain protein
H0N27_RS07690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0N27_RS07720	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0N27_RS07725	COG0542	response to heat
H0N27_RS07750	COG1902	pentaerythritol trinitrate reductase activity
H0N27_RS07750	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N27_RS07795	COG2323	membrane
H0N27_RS07805	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0N27_RS07815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0N27_RS07820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0N27_RS07825	COG0183	Belongs to the thiolase family
H0N27_RS07830	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0N27_RS07835	COG0596	Alpha beta hydrolase
H0N27_RS07840	COG2271	Major facilitator Superfamily
H0N27_RS07845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0N27_RS07850	COG3485	protocatechuate 3,4-dioxygenase
H0N27_RS07855	COG3485	protocatechuate 3,4-dioxygenase
H0N27_RS07860	COG0710	3-dehydroquinate dehydratase activity
H0N27_RS07865	COG3420	alginic acid biosynthetic process
H0N27_RS07870	COG3659	wide pore channel activity
H0N27_RS07875	COG4993	Dehydrogenase
H0N27_RS07885	COG2391	methyltransferase activity
H0N27_RS07900	COG1414	Transcriptional regulator
H0N27_RS07905	COG0583	DNA-binding transcription factor activity
H0N27_RS07910	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS07935	COG2814	Major facilitator Superfamily
H0N27_RS07945	COG0154	amidase activity
H0N27_RS07965	COG4638	Rieske (2fe-2S)
H0N27_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS07985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS07995	COG3733	amine oxidase
H0N27_RS08005	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS08015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N27_RS08020	COG0183	Belongs to the thiolase family
H0N27_RS08025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0N27_RS08030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0N27_RS08040	COG4829	muconolactone delta-isomerase
H0N27_RS08045	COG4948	Mandelate Racemase Muconate Lactonizing
H0N27_RS08050	COG0583	DNA-binding transcription factor activity
H0N27_RS08060	COG2186	Transcriptional regulator
H0N27_RS08080	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS08095	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N27_RS08095	COG1902	pentaerythritol trinitrate reductase activity
H0N27_RS08110	COG0789	Transcriptional regulator
H0N27_RS08135	COG1309	transcriptional regulator
H0N27_RS08145	COG1335	isochorismatase
H0N27_RS08150	COG0583	DNA-binding transcription factor activity
H0N27_RS08160	COG0475	glutathione-regulated potassium exporter activity
H0N27_RS08160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0N27_RS08170	COG1473	amidohydrolase
H0N27_RS08180	COG2831	hemolysin activation secretion protein
H0N27_RS08185	COG3210	domain, Protein
H0N27_RS08215	COG2188	Transcriptional regulator
H0N27_RS08230	COG0583	DNA-binding transcription factor activity
H0N27_RS08255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0N27_RS08260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0N27_RS08280	COG1566	PFAM secretion protein HlyD family protein
H0N27_RS08295	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS08300	COG0129	dihydroxy-acid dehydratase activity
H0N27_RS08310	COG0583	DNA-binding transcription factor activity
H0N27_RS08315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0N27_RS08325	COG2084	Dehydrogenase
H0N27_RS08330	COG2207	Transcriptional regulator
H0N27_RS08335	COG1064	alcohol dehydrogenase
H0N27_RS08345	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0N27_RS08350	COG1120	ATPase activity
H0N27_RS08370	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0N27_RS08420	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0N27_RS08455	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
H0N27_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS08490	COG2207	Transcriptional regulator
H0N27_RS08500	COG2205	protein histidine kinase activity
H0N27_RS08505	COG0745	RESPONSE REGULATOR receiver
H0N27_RS08510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS08515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0N27_RS08530	COG3539	Fimbrial protein
H0N27_RS08555	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0N27_RS08565	COG0753	catalase activity
H0N27_RS08580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0N27_RS08640	COG3433	isochorismatase activity
H0N27_RS08640	COG1535	isochorismatase
H0N27_RS08645	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS08650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H0N27_RS08655	COG4149	molybdate abc transporter
H0N27_RS08660	COG0725	ABC transporter, periplasmic molybdate-binding protein
H0N27_RS08670	COG4638	Rieske (2fe-2S)
H0N27_RS08675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0N27_RS08680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N27_RS08680	COG0543	2 iron, 2 sulfur cluster binding
H0N27_RS08695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS08720	COG2207	Transcriptional regulator
H0N27_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS08730	COG2610	gluconate transmembrane transporter activity
H0N27_RS08745	COG0583	DNA-binding transcription factor activity
H0N27_RS08760	COG2031	fatty acid transporter
H0N27_RS08765	COG0183	Belongs to the thiolase family
H0N27_RS08770	COG0583	DNA-binding transcription factor activity
H0N27_RS08775	COG0583	DNA-binding transcription factor activity
H0N27_RS08790	COG1027	Aspartate ammonia-lyase
H0N27_RS08800	COG0477	Major facilitator Superfamily
H0N27_RS08820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N27_RS08825	COG4521	taurine ABC transporter
H0N27_RS08840	COG2188	Transcriptional regulator
H0N27_RS08850	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0N27_RS08855	COG1733	regulation of RNA biosynthetic process
H0N27_RS08860	COG3708	Transcriptional regulator
H0N27_RS08860	COG2207	Transcriptional regulator
H0N27_RS08875	COG0730	response to heat
H0N27_RS08885	COG3453	Protein conserved in bacteria
H0N27_RS08885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N27_RS08895	COG3781	membrane
H0N27_RS08900	COG1063	alcohol dehydrogenase
H0N27_RS08910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0N27_RS08915	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0N27_RS08920	COG0022	dehydrogenase e1 component
H0N27_RS08925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0N27_RS08930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0N27_RS08945	COG3706	GGDEF domain
H0N27_RS08960	COG0133	tryptophan synthase activity
H0N27_RS08970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0N27_RS09005	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0N27_RS09030	COG2226	methyltransferase
H0N27_RS09085	COG0842	Transport permease protein
H0N27_RS09090	COG0842	Transport permease protein
H0N27_RS09095	COG1131	(ABC) transporter
H0N27_RS09110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0N27_RS09115	COG4773	Receptor
H0N27_RS09140	COG0730	response to heat
H0N27_RS09145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0N27_RS09160	COG0406	alpha-ribazole phosphatase activity
H0N27_RS09180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0N27_RS09210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0N27_RS09220	COG4264	IucA IucC family
H0N27_RS09225	COG4264	IucA IucC family
H0N27_RS09245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0N27_RS09260	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS09265	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS09270	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0N27_RS09275	COG2207	Transcriptional regulator
H0N27_RS09280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0N27_RS09285	COG0776	regulation of translation
H0N27_RS09310	COG0822	iron-sulfur transferase activity
H0N27_RS09315	COG0316	Belongs to the HesB IscA family
H0N27_RS09345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0N27_RS09365	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0N27_RS09370	COG0702	epimerase
H0N27_RS09405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0N27_RS09415	COG0339	signal peptide processing
H0N27_RS09425	COG4166	transmembrane transport
H0N27_RS09460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0N27_RS09465	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0N27_RS09495	COG0776	regulation of translation
H0N27_RS09560	COG0084	hydrolase, TatD family'
H0N27_RS09580	COG1663	tetraacyldisaccharide 4'-kinase activity
H0N27_RS09585	COG1132	(ABC) transporter
H0N27_RS09595	COG0811	peptide transport
H0N27_RS09600	COG1475	DNA binding
H0N27_RS09605	COG1192	Involved in chromosome partitioning
H0N27_RS09615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0N27_RS09630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0N27_RS09635	COG0191	fructose-bisphosphate aldolase activity
H0N27_RS09655	COG0424	maF-like protein
H0N27_RS09660	COG2850	peptidyl-arginine hydroxylation
H0N27_RS09670	COG0640	Transcriptional regulator
H0N27_RS09680	COG3619	membrane
H0N27_RS09685	COG3122	Protein conserved in bacteria
H0N27_RS09690	COG1132	(ABC) transporter
H0N27_RS09710	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0N27_RS09715	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0N27_RS09725	COG0506	proline dehydrogenase activity
H0N27_RS09725	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0N27_RS09725	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0N27_RS09730	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H0N27_RS09745	COG3698	Phosphodiester glycosidase
H0N27_RS09755	COG2353	YceI-like domain
H0N27_RS09765	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0N27_RS09810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0N27_RS09810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0N27_RS09835	COG3539	Fimbrial protein
H0N27_RS09840	COG3121	Chaperone
H0N27_RS09865	COG0697	spore germination
H0N27_RS09875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0N27_RS09885	COG0583	DNA-binding transcription factor activity
H0N27_RS09905	COG1309	transcriptional regulator
H0N27_RS09920	COG1522	sequence-specific DNA binding
H0N27_RS09930	COG1126	abc transporter atp-binding protein
H0N27_RS09935	COG0765	amino acid transport
H0N27_RS09940	COG0765	amino acid transport
H0N27_RS09970	COG1464	Belongs to the NlpA lipoprotein family
H0N27_RS09980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0N27_RS09985	COG2011	ABC-type metal ion transport system permease component
H0N27_RS09990	COG0012	GTP binding
H0N27_RS10015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0N27_RS10055	COG0386	Belongs to the glutathione peroxidase family
H0N27_RS10065	COG0436	Aminotransferase
H0N27_RS10105	COG3634	alkyl hydroperoxide reductase activity
H0N27_RS10120	COG0583	DNA-binding transcription factor activity
H0N27_RS10125	COG0798	PFAM Bile acid sodium symporter
H0N27_RS10130	COG0640	Transcriptional regulator
H0N27_RS10145	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H0N27_RS10155	COG0583	DNA-binding transcription factor activity
H0N27_RS10165	COG1953	Uracil, thiamine, allantoin
H0N27_RS10175	COG2175	clavaminate synthase activity
H0N27_RS10180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N27_RS10185	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H0N27_RS10190	COG4521	taurine ABC transporter
H0N27_RS10200	COG0477	Major facilitator Superfamily
H0N27_RS10220	COG1271	oxidase subunit
H0N27_RS10225	COG1294	oxidase, subunit
H0N27_RS10235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N27_RS10255	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0N27_RS10275	COG3052	prosthetic group binding
H0N27_RS10280	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H0N27_RS10290	COG0300	oxidoreductase activity
H0N27_RS10315	COG1346	cytolysis
H0N27_RS10325	COG0583	DNA-binding transcription factor activity
H0N27_RS10330	COG0625	glutathione transferase activity
H0N27_RS10335	COG0625	glutathione transferase activity
H0N27_RS10340	COG0583	DNA-binding transcription factor activity
H0N27_RS10355	COG1045	serine acetyltransferase
H0N27_RS10360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0N27_RS10365	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0N27_RS10370	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS10380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N27_RS10385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N27_RS10395	COG0765	amino acid transport
H0N27_RS10400	COG0765	amino acid transport
H0N27_RS10420	COG0784	Response regulator, receiver
H0N27_RS10420	COG2205	protein histidine kinase activity
H0N27_RS10440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0N27_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS10510	COG0583	DNA-binding transcription factor activity
H0N27_RS10530	COG0318	PFAM AMP-dependent synthetase and ligase
H0N27_RS10535	COG1309	transcriptional regulator
H0N27_RS10540	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS10545	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0N27_RS10550	COG1024	Enoyl-CoA hydratase
H0N27_RS10555	COG4770	biotin carboxylase activity
H0N27_RS10565	COG0583	DNA-binding transcription factor activity
H0N27_RS10580	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS10590	COG2814	Major facilitator Superfamily
H0N27_RS10600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0N27_RS10605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0N27_RS10610	COG2814	Major facilitator Superfamily
H0N27_RS10615	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS10620	COG1024	Enoyl-CoA hydratase
H0N27_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS10630	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0N27_RS10635	COG0183	Belongs to the thiolase family
H0N27_RS10645	COG2814	Major facilitator Superfamily
H0N27_RS10655	COG1024	Enoyl-CoA hydratase
H0N27_RS10670	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS10675	COG2814	Major facilitator Superfamily
H0N27_RS10680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0N27_RS10685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0N27_RS10700	COG3842	ATPase activity
H0N27_RS10705	COG1840	ABC-type Fe3 transport system, periplasmic component
H0N27_RS10715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N27_RS10720	COG1414	Transcriptional regulator
H0N27_RS10730	COG0583	DNA-binding transcription factor activity
H0N27_RS10735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0N27_RS10740	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS10750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0N27_RS10760	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS10765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0N27_RS10770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS10775	COG2267	carboxylic ester hydrolase activity
H0N27_RS10795	COG3038	cytochrome b561
H0N27_RS10800	COG0753	catalase activity
H0N27_RS10830	COG0232	Belongs to the dGTPase family. Type 2 subfamily
H0N27_RS10835	COG2050	protein possibly involved in aromatic compounds catabolism
H0N27_RS10845	COG3327	negative regulation of DNA-templated transcription, initiation
H0N27_RS10850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H0N27_RS10855	COG0183	Belongs to the thiolase family
H0N27_RS10860	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0N27_RS10865	COG1024	Enoyl-CoA hydratase
H0N27_RS10870	COG1024	Enoyl-CoA hydratase
H0N27_RS10875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N27_RS10880	COG2151	metal-sulfur cluster biosynthetic enzyme
H0N27_RS10885	COG3396	Phenylacetate-CoA oxygenase
H0N27_RS10890	COG3460	Phenylacetate-CoA oxygenase
H0N27_RS10895	COG3396	Phenylacetate-CoA oxygenase
H0N27_RS10900	COG2030	dehydratase
H0N27_RS10900	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS10905	COG1760	l-serine dehydratase
H0N27_RS10910	COG0531	amino acid
H0N27_RS10915	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS10940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0N27_RS10960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N27_RS10970	COG0789	Transcriptional regulator
H0N27_RS10980	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0N27_RS10995	COG2807	transmembrane transport
H0N27_RS11000	COG0590	tRNA wobble adenosine to inosine editing
H0N27_RS11115	COG1116	anion transmembrane transporter activity
H0N27_RS11120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0N27_RS11130	COG0864	Transcriptional regulator
H0N27_RS11140	COG1733	regulation of RNA biosynthetic process
H0N27_RS11145	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS11150	COG0439	Biotin carboxylase
H0N27_RS11165	COG1063	alcohol dehydrogenase
H0N27_RS11175	COG1309	transcriptional regulator
H0N27_RS11185	COG0038	chloride channel
H0N27_RS11190	COG4770	biotin carboxylase activity
H0N27_RS11210	COG1914	H( )-stimulated, divalent metal cation uptake system
H0N27_RS11215	COG0583	DNA-binding transcription factor activity
H0N27_RS11280	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0N27_RS11300	COG2814	Major facilitator Superfamily
H0N27_RS11310	COG1560	Kdo2-lipid A biosynthetic process
H0N27_RS11320	COG5006	permease, DMT superfamily
H0N27_RS11325	COG1522	sequence-specific DNA binding
H0N27_RS11340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0N27_RS11350	COG4122	O-methyltransferase activity
H0N27_RS11380	COG1538	Outer membrane efflux protein
H0N27_RS11385	COG1137	ATPase activity
H0N27_RS11390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0N27_RS11400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0N27_RS11405	COG0517	IMP dehydrogenase activity
H0N27_RS11405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0N27_RS11450	COG2814	Major facilitator Superfamily
H0N27_RS11485	COG1278	Cold shock
H0N27_RS11490	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS11520	COG1570	exodeoxyribonuclease VII activity
H0N27_RS11570	COG0583	DNA-binding transcription factor activity
H0N27_RS11575	COG4638	Rieske (2fe-2S)
H0N27_RS11580	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0N27_RS11585	COG0633	Ferredoxin
H0N27_RS11585	COG0543	2 iron, 2 sulfur cluster binding
H0N27_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS11595	COG3135	benzoate transporter
H0N27_RS11600	COG2814	Major facilitator Superfamily
H0N27_RS11615	COG1643	Atp-dependent helicase
H0N27_RS11620	COG0450	alkyl hydroperoxide reductase
H0N27_RS11630	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0N27_RS11640	COG3634	alkyl hydroperoxide reductase activity
H0N27_RS11660	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0N27_RS11665	COG0625	glutathione transferase activity
H0N27_RS11675	COG2885	chlorophyll binding
H0N27_RS11710	COG0542	response to heat
H0N27_RS11725	COG1765	OsmC-like protein
H0N27_RS11740	COG0667	Aldo Keto reductase
H0N27_RS11755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0N27_RS11770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0N27_RS11790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0N27_RS11800	COG3038	cytochrome b561
H0N27_RS11805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0N27_RS11810	COG2252	PERMEase
H0N27_RS11820	COG2072	flavoprotein involved in K transport
H0N27_RS11835	COG1741	Belongs to the pirin family
H0N27_RS11840	COG1309	transcriptional regulator
H0N27_RS11850	COG0300	oxidoreductase activity
H0N27_RS11855	COG2072	flavoprotein involved in K transport
H0N27_RS11860	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H0N27_RS11865	COG2207	Transcriptional regulator
H0N27_RS11905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0N27_RS11920	COG2814	Major facilitator Superfamily
H0N27_RS11925	COG1024	Enoyl-CoA hydratase
H0N27_RS11930	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS11940	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS11965	COG2186	Transcriptional regulator
H0N27_RS11970	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS11980	COG4948	Mandelate Racemase Muconate Lactonizing
H0N27_RS11985	COG2271	Major facilitator Superfamily
H0N27_RS11990	COG2721	sulfolactate sulfo-lyase activity
H0N27_RS12010	COG1113	amino acid transport
H0N27_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS12050	COG0531	amino acid
H0N27_RS12060	COG1113	amino acid transport
H0N27_RS12105	COG3209	COG3209 Rhs family protein
H0N27_RS12125	COG4269	membrane
H0N27_RS12140	COG1902	pentaerythritol trinitrate reductase activity
H0N27_RS12140	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N27_RS12150	COG4251	negative regulation of phosphorylation
H0N27_RS12150	COG5001	Diguanylate cyclase
H0N27_RS12150	COG3706	GGDEF domain
H0N27_RS12150	COG2203	Gaf domain
H0N27_RS12160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0N27_RS12180	COG4172	Belongs to the ABC transporter superfamily
H0N27_RS12185	COG4239	(ABC) transporter, permease
H0N27_RS12190	COG4174	ABC transporter (Permease)
H0N27_RS12200	COG1388	LysM domain
H0N27_RS12200	COG0741	lytic transglycosylase activity
H0N27_RS12200	COG1388	LysM domain
H0N27_RS12200	COG0741	lytic transglycosylase activity
H0N27_RS12205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0N27_RS12245	COG0583	DNA-binding transcription factor activity
H0N27_RS12250	COG1279	arginine transmembrane transporter activity
H0N27_RS12270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N27_RS12275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N27_RS12280	COG0006	proline dipeptidase activity
H0N27_RS12430	COG3646	Phage regulatory protein
H0N27_RS12655	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0N27_RS12680	COG3384	dioxygenase
H0N27_RS12690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0N27_RS12695	COG2878	Part of a membrane complex involved in electron transport
H0N27_RS12700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0N27_RS12725	COG0768	penicillin binding
H0N27_RS12730	COG0742	ribosomal rna small subunit methyltransferase
H0N27_RS12745	COG0830	nickel cation binding
H0N27_RS12755	COG0804	urea catabolic process
H0N27_RS12795	COG1253	flavin adenine dinucleotide binding
H0N27_RS12800	COG2851	Citrate transporter
H0N27_RS12850	COG1773	rubredoxin
H0N27_RS12855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0N27_RS12865	COG0583	DNA-binding transcription factor activity
H0N27_RS12895	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0N27_RS12900	COG4181	ATPase activity
H0N27_RS12945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0N27_RS12965	COG0306	phosphate transporter
H0N27_RS12975	COG3958	Transketolase
H0N27_RS12980	COG3959	Transketolase, thiamine diphosphate binding domain
H0N27_RS12985	COG2271	Major facilitator Superfamily
H0N27_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS12995	COG0583	DNA-binding transcription factor activity
H0N27_RS13010	COG2223	nitrite transmembrane transporter activity
H0N27_RS13015	COG2207	Transcriptional regulator
H0N27_RS13020	COG2066	Belongs to the glutaminase family
H0N27_RS13025	COG0242	peptide deformylase activity
H0N27_RS13030	COG0477	Major facilitator Superfamily
H0N27_RS13040	COG0028	Belongs to the TPP enzyme family
H0N27_RS13055	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS13060	COG2267	carboxylic ester hydrolase activity
H0N27_RS13070	COG2271	Major facilitator Superfamily
H0N27_RS13075	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0N27_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS13105	COG1414	Transcriptional regulator
H0N27_RS13120	COG1024	Enoyl-CoA hydratase
H0N27_RS13130	COG1215	transferase activity, transferring glycosyl groups
H0N27_RS13135	COG1649	PFAM Uncharacterised BCR, COG1649
H0N27_RS13135	COG0726	polysaccharide deacetylase
H0N27_RS13145	COG4681	YaeQ
H0N27_RS13155	COG0523	cobalamin synthesis protein
H0N27_RS13165	COG1607	acyl-coa hydrolase
H0N27_RS13175	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N27_RS13180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0N27_RS13185	COG1309	transcriptional regulator
H0N27_RS13210	COG2040	homocysteine
H0N27_RS13215	COG0531	amino acid
H0N27_RS13245	COG0477	Major facilitator Superfamily
H0N27_RS13265	COG1401	restriction endodeoxyribonuclease activity
H0N27_RS13295	COG0405	Gamma-glutamyltransferase
H0N27_RS13300	COG2814	Major facilitator Superfamily
H0N27_RS13310	COG2050	protein possibly involved in aromatic compounds catabolism
H0N27_RS13325	COG1090	epimerase
H0N27_RS13345	COG0420	3'-5' exonuclease activity
H0N27_RS13370	COG0735	belongs to the Fur family
H0N27_RS13375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0N27_RS13395	COG0121	glutamine amidotransferase
H0N27_RS13410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0N27_RS13420	COG0210	DNA helicase
H0N27_RS13425	COG2885	chlorophyll binding
H0N27_RS13430	COG0204	Acyl-transferase
H0N27_RS13445	COG2894	cell division
H0N27_RS13460	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS13465	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0N27_RS13465	COG1674	ftsk spoiiie
H0N27_RS13470	COG0492	ferredoxin-NADP+ reductase activity
H0N27_RS13475	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0N27_RS13485	COG0456	acetyltransferase
H0N27_RS13530	COG1981	membrane
H0N27_RS13545	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0N27_RS13545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0N27_RS13565	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS13575	COG0657	acetylesterase activity
H0N27_RS13585	COG0473	3-isopropylmalate dehydrogenase activity
H0N27_RS13590	COG0583	DNA-binding transcription factor activity
H0N27_RS13610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N27_RS13635	COG0564	pseudouridine synthase activity
H0N27_RS13645	COG0358	DNA primase activity
H0N27_RS13660	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0N27_RS13690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0N27_RS13720	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0N27_RS13730	COG0351	phosphomethylpyrimidine kinase
H0N27_RS13730	COG0352	thiamine-phosphate diphosphorylase activity
H0N27_RS13730	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0N27_RS13735	COG1652	LysM domain
H0N27_RS13760	COG1399	metal-binding, possibly nucleic acid-binding protein
H0N27_RS13765	COG3101	peptidyl-lysine hydroxylation
H0N27_RS13770	COG0009	L-threonylcarbamoyladenylate synthase
H0N27_RS13775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H0N27_RS13780	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0N27_RS13795	COG4106	trans-aconitate 2-methyltransferase activity
H0N27_RS13810	COG2226	methyltransferase
H0N27_RS13810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N27_RS13810	COG0596	Alpha beta hydrolase
H0N27_RS13815	COG1877	trehalose-phosphatase activity
H0N27_RS13820	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0N27_RS13825	COG2223	nitrite transmembrane transporter activity
H0N27_RS13845	COG1196	nuclear chromosome segregation
H0N27_RS13855	COG0730	response to heat
H0N27_RS13870	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0N27_RS13880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0N27_RS13930	COG0489	protein tyrosine kinase activity
H0N27_RS13940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0N27_RS13940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0N27_RS13970	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0N27_RS13975	COG2081	HI0933 family
H0N27_RS13985	COG0668	transmembrane transport
H0N27_RS14005	COG0583	DNA-binding transcription factor activity
H0N27_RS14025	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0N27_RS14030	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0N27_RS14060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0N27_RS14100	COG0745	RESPONSE REGULATOR receiver
H0N27_RS14120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0N27_RS14135	COG0384	phenazine biosynthesis protein PhzF
H0N27_RS14220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0N27_RS14235	COG0583	DNA-binding transcription factor activity
H0N27_RS14265	COG0583	DNA-binding transcription factor activity
H0N27_RS14280	COG0583	DNA-binding transcription factor activity
H0N27_RS14285	COG1053	succinate dehydrogenase
H0N27_RS14295	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0N27_RS14300	COG2814	Major facilitator Superfamily
H0N27_RS14305	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS14310	COG0583	DNA-binding transcription factor activity
H0N27_RS14315	COG1063	alcohol dehydrogenase
H0N27_RS14345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0N27_RS14350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0N27_RS14355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0N27_RS14370	COG3667	copper resistance
H0N27_RS14375	COG2132	Multicopper oxidase
H0N27_RS14385	COG0561	phosphatase activity
H0N27_RS14390	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0N27_RS14415	COG1214	PFAM Peptidase M22, glycoprotease
H0N27_RS14475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0N27_RS14480	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0N27_RS14485	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0N27_RS14545	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0N27_RS14555	COG1846	Transcriptional regulator
H0N27_RS14560	COG1764	response to oxidative stress
H0N27_RS14600	COG0037	tRNA processing
H0N27_RS14610	COG0248	Ppx GppA phosphatase
H0N27_RS14640	COG0072	phenylalanine-tRNA ligase activity
H0N27_RS14680	COG1238	metal cluster binding
H0N27_RS14685	COG0625	glutathione transferase activity
H0N27_RS14700	COG0318	PFAM AMP-dependent synthetase and ligase
H0N27_RS14705	COG3028	Belongs to the UPF0307 family
H0N27_RS14710	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0N27_RS14730	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0N27_RS14735	COG0617	tRNA 3'-terminal CCA addition
H0N27_RS14740	COG1555	photosystem II stabilization
H0N27_RS14745	COG3956	TIGRFAM MazG family protein
H0N27_RS14755	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0N27_RS14775	COG5002	protein histidine kinase activity
H0N27_RS14775	COG2205	protein histidine kinase activity
H0N27_RS14775	COG0784	Response regulator, receiver
H0N27_RS14780	COG1024	Enoyl-CoA hydratase
H0N27_RS14785	COG2084	Dehydrogenase
H0N27_RS14790	COG3622	Belongs to the hyi family
H0N27_RS14820	COG0697	spore germination
H0N27_RS14830	COG2814	Major facilitator Superfamily
H0N27_RS14835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0N27_RS14845	COG0583	DNA-binding transcription factor activity
H0N27_RS14855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0N27_RS14870	COG0084	hydrolase, TatD family'
H0N27_RS14885	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H0N27_RS14915	COG0440	acetolactate synthase activity
H0N27_RS14920	COG0028	Belongs to the TPP enzyme family
H0N27_RS14945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0N27_RS14950	COG0577	efflux transmembrane transporter activity
H0N27_RS14950	COG1136	(ABC) transporter
H0N27_RS14955	COG1538	Outer membrane efflux protein
H0N27_RS14970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0N27_RS14975	COG1162	GTPase activity
H0N27_RS14985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0N27_RS15025	COG1426	Protein conserved in bacteria
H0N27_RS15060	COG0793	Belongs to the peptidase S41A family
H0N27_RS15075	COG2267	carboxylic ester hydrolase activity
H0N27_RS15085	COG1012	belongs to the aldehyde dehydrogenase family
H0N27_RS15090	COG3265	gluconokinase activity
H0N27_RS15100	COG0800	Aldolase
H0N27_RS15110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0N27_RS15115	COG0857	belongs to the CobB CobQ family
H0N27_RS15115	COG0280	phosphate acetyltransferase
H0N27_RS15120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0N27_RS15120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0N27_RS15140	COG0740	serine-type endopeptidase activity
H0N27_RS15150	COG4774	siderophore transport
H0N27_RS15160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0N27_RS15170	COG2813	Specifically methylates the guanine in position
H0N27_RS15170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0N27_RS15270	COG0788	formyltetrahydrofolate deformylase activity
H0N27_RS15295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0N27_RS15295	COG4651	solute:proton antiporter activity
H0N27_RS15315	COG0724	RNA recognition motif
H0N27_RS15320	COG0210	DNA helicase
H0N27_RS15345	COG1733	regulation of RNA biosynthetic process
H0N27_RS15355	COG2900	Belongs to the SlyX family
H0N27_RS15360	COG0488	(ABC) transporter
H0N27_RS15365	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS15370	COG1560	Kdo2-lipid A biosynthetic process
H0N27_RS15380	COG1301	dicarboxylic acid transport
H0N27_RS15435	COG0473	3-isopropylmalate dehydrogenase activity
H0N27_RS15490	COG0583	DNA-binding transcription factor activity
H0N27_RS15500	COG0625	glutathione transferase activity
H0N27_RS15505	COG2378	regulation of single-species biofilm formation
H0N27_RS15510	COG0546	phosphoglycolate phosphatase activity
H0N27_RS15520	COG1530	ribonuclease E activity
H0N27_RS15525	COG0318	PFAM AMP-dependent synthetase and ligase
H0N27_RS15540	COG0583	DNA-binding transcription factor activity
H0N27_RS15545	COG4221	oxidoreductase activity
H0N27_RS15550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0N27_RS15560	COG0534	Mate efflux family protein
H0N27_RS15575	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0N27_RS15600	COG0493	'glutamate synthase
H0N27_RS15600	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0N27_RS15610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0N27_RS15615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0N27_RS15630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0N27_RS15640	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0N27_RS15640	COG0644	oxidoreductase
H0N27_RS15650	COG0425	Belongs to the sulfur carrier protein TusA family
H0N27_RS15655	COG4535	Mg2 and Co2 transporter CorC
H0N27_RS15685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0N27_RS15690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0N27_RS15690	COG0475	glutathione-regulated potassium exporter activity
H0N27_RS15705	COG0484	heat shock protein binding
H0N27_RS15710	COG0789	Transcriptional regulator
H0N27_RS15715	COG0598	Magnesium transport protein CorA
H0N27_RS15730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0N27_RS15735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0N27_RS15740	COG1074	ATP-dependent DNA helicase activity
H0N27_RS15745	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0N27_RS15765	COG2226	methyltransferase
H0N27_RS15780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0N27_RS15785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0N27_RS15800	COG2111	Na H antiporter
H0N27_RS15800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0N27_RS15805	COG1006	Multisubunit Na H antiporter MnhC subunit
H0N27_RS15810	COG0651	ATP synthesis coupled electron transport
H0N27_RS15815	COG1863	multisubunit Na H antiporter MnhE subunit
H0N27_RS15820	COG2212	antiporter activity
H0N27_RS15825	COG1320	monovalent cation:proton antiporter activity
H0N27_RS15840	COG0195	Participates in both transcription termination and antitermination
H0N27_RS15890	COG0237	dephospho-CoA kinase activity
H0N27_RS15900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0N27_RS15915	COG0497	DNA recombination
H0N27_RS15925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0N27_RS15955	COG2169	Transcriptional regulator
H0N27_RS15955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0N27_RS15960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0N27_RS16015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0N27_RS16030	COG0326	Molecular chaperone. Has ATPase activity
H0N27_RS16045	COG2056	Na+-H+ antiporter family
H0N27_RS16050	COG0596	Alpha beta hydrolase
H0N27_RS16145	COG0546	phosphoglycolate phosphatase activity
H0N27_RS16150	COG1716	ATPase activity
H0N27_RS16195	COG0181	hydroxymethylbilane synthase activity
H0N27_RS16205	COG3275	phosphorelay sensor kinase activity
H0N27_RS16230	COG0697	spore germination
H0N27_RS16255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0N27_RS16260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0N27_RS16265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0N27_RS16270	COG0772	Belongs to the SEDS family
H0N27_RS16295	COG4974	Belongs to the 'phage' integrase family
H0N27_RS16300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N27_RS16310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0N27_RS16320	COG2197	response regulator
H0N27_RS16335	COG0793	Belongs to the peptidase S41A family
H0N27_RS16340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0N27_RS16345	COG0795	lipopolysaccharide-transporting ATPase activity
H0N27_RS16385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0N27_RS16385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0N27_RS16395	COG0004	ammonium transporteR
H0N27_RS16400	COG0347	Belongs to the P(II) protein family
H0N27_RS16410	COG0606	chelatase, subunit chli
H0N27_RS16415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0N27_RS16425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0N27_RS16440	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0N27_RS16455	COG0318	PFAM AMP-dependent synthetase and ligase
H0N27_RS16465	COG0477	Major facilitator Superfamily
H0N27_RS16470	COG2860	membrane
H0N27_RS16475	COG3012	SEC-C Motif Domain Protein
H0N27_RS16480	COG1253	flavin adenine dinucleotide binding
H0N27_RS16490	COG0477	Major facilitator Superfamily
H0N27_RS16500	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0N27_RS16535	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0N27_RS16545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0N27_RS16580	COG1309	transcriptional regulator
H0N27_RS16615	COG0758	DNA mediated transformation
H0N27_RS16625	COG0697	spore germination
H0N27_RS16630	COG1309	transcriptional regulator
H0N27_RS16645	COG0386	Belongs to the glutathione peroxidase family
H0N27_RS16710	COG1121	(ABC) transporter
H0N27_RS16715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0N27_RS16720	COG1280	lysine exporter protein (LysE YggA)
H0N27_RS16725	COG2837	iron assimilation
H0N27_RS16735	COG0281	malic enzyme
H0N27_RS16780	COG0519	Catalyzes the synthesis of GMP from XMP
H0N27_RS16780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0N27_RS16785	COG4399	Belongs to the UPF0754 family
H0N27_RS16790	COG2259	Doxx family
H0N27_RS16795	COG0586	Pfam SNARE associated Golgi protein
H0N27_RS16810	COG1192	Involved in chromosome partitioning
H0N27_RS16820	COG0271	Belongs to the BolA IbaG family
H0N27_RS16860	COG3321	synthase
H0N27_RS16860	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H0N27_RS16860	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0N27_RS16860	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0N27_RS16865	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS16875	COG2197	response regulator
H0N27_RS16885	COG3916	Acyl-homoserine-lactone synthase
H0N27_RS16890	COG0477	Major facilitator Superfamily
H0N27_RS16895	COG1024	Enoyl-CoA hydratase
H0N27_RS16900	COG1024	Enoyl-CoA hydratase
H0N27_RS16905	COG1960	acyl-CoA dehydrogenase activity
H0N27_RS16910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0N27_RS16930	COG1113	amino acid transport
H0N27_RS16935	COG1113	amino acid transport
H0N27_RS16940	COG0251	oxidation-reduction process
H0N27_RS16980	COG0564	pseudouridine synthase activity
H0N27_RS17040	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0N27_RS17055	COG1802	Transcriptional regulator
H0N27_RS17060	COG1448	Aminotransferase
H0N27_RS17065	COG0277	FAD linked oxidase domain protein
H0N27_RS17075	COG2186	Transcriptional regulator
H0N27_RS17085	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0N27_RS17095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0N27_RS17110	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0N27_RS17115	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0N27_RS17125	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0N27_RS17130	COG0438	transferase activity, transferring glycosyl groups
H0N27_RS17140	COG0438	transferase activity, transferring glycosyl groups
H0N27_RS17145	COG1215	transferase activity, transferring glycosyl groups
H0N27_RS17155	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0N27_RS17185	COG0728	peptidoglycan biosynthetic process
H0N27_RS17190	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0N27_RS17245	COG0546	phosphoglycolate phosphatase activity
H0N27_RS17250	COG1028	Short-chain dehydrogenase reductase Sdr
H0N27_RS17270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N27_RS17275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0N27_RS17280	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0N27_RS17285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0N27_RS17290	COG1116	anion transmembrane transporter activity
H0N27_RS17295	COG1309	transcriptional regulator
H0N27_RS17300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0N27_RS17310	COG0196	riboflavin kinase activity
H0N27_RS17315	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0N27_RS17325	COG1047	Peptidyl-prolyl cis-trans
H0N27_RS17365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0N27_RS17370	COG0657	acetylesterase activity
H0N27_RS17420	COG2951	lytic endotransglycosylase activity
H0N27_RS17425	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0N27_RS17440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0N27_RS17450	COG0671	phosphoesterase, PA-phosphatase related
H0N27_RS17455	COG0861	Integral membrane protein TerC family
H0N27_RS17465	COG0754	glutathionylspermidine amidase activity
H0N27_RS17475	COG0402	S-adenosylhomocysteine deaminase activity
H0N27_RS17490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0N27_RS17495	COG1230	cation diffusion facilitator family transporter
H0N27_RS17510	COG0706	membrane insertase activity