locus-tag	class	description
A388_RS00005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
A388_RS00010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
A388_RS00015	COG0596	Alpha beta hydrolase
A388_RS00040	COG0488	(ABC) transporter
A388_RS00045	COG0586	Pfam SNARE associated Golgi protein
A388_RS00055	COG0187	DNA topoisomerase II activity
A388_RS00065	COG0592	DNA-directed DNA polymerase activity
A388_RS00090	COG0706	membrane insertase activity
A388_RS00105	COG1230	cation diffusion facilitator family transporter
A388_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A388_RS00125	COG0402	S-adenosylhomocysteine deaminase activity
A388_RS00135	COG0754	glutathionylspermidine amidase activity
A388_RS00145	COG0861	Integral membrane protein TerC family
A388_RS00150	COG0671	phosphoesterase, PA-phosphatase related
A388_RS00160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
A388_RS00180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
A388_RS00235	COG0657	acetylesterase activity
A388_RS00240	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
A388_RS00280	COG1047	Peptidyl-prolyl cis-trans
A388_RS00290	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
A388_RS00295	COG0196	riboflavin kinase activity
A388_RS00305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
A388_RS00310	COG1309	transcriptional regulator
A388_RS00315	COG1116	anion transmembrane transporter activity
A388_RS00320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A388_RS00325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A388_RS00330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A388_RS00335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A388_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS00360	COG0546	phosphoglycolate phosphatase activity
A388_RS00420	COG3023	N-Acetylmuramoyl-L-alanine amidase
A388_RS00425	COG0728	peptidoglycan biosynthetic process
A388_RS00450	COG1596	polysaccharide export
A388_RS00455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A388_RS00465	COG5039	Polysaccharide pyruvyl transferase
A388_RS00470	COG1216	Glycosyl transferase, family 2
A388_RS00490	COG0438	transferase activity, transferring glycosyl groups
A388_RS00495	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
A388_RS00505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
A388_RS00515	COG1210	Utp--glucose-1-phosphate uridylyltransferase
A388_RS00530	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A388_RS00535	COG2194	sulfuric ester hydrolase activity
A388_RS00550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A388_RS00560	COG2186	Transcriptional regulator
A388_RS00570	COG0277	FAD linked oxidase domain protein
A388_RS00575	COG1448	Aminotransferase
A388_RS00585	COG1802	Transcriptional regulator
A388_RS00600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
A388_RS00645	COG0564	pseudouridine synthase activity
A388_RS00685	COG0251	oxidation-reduction process
A388_RS00690	COG1113	amino acid transport
A388_RS00695	COG1113	amino acid transport
A388_RS00715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A388_RS00720	COG1960	acyl-CoA dehydrogenase activity
A388_RS00725	COG1024	Enoyl-CoA hydratase
A388_RS00730	COG1024	Enoyl-CoA hydratase
A388_RS00735	COG0477	Major facilitator Superfamily
A388_RS00740	COG2197	response regulator
A388_RS00765	COG0271	Belongs to the BolA IbaG family
A388_RS00775	COG1192	Involved in chromosome partitioning
A388_RS00790	COG0586	Pfam SNARE associated Golgi protein
A388_RS00795	COG2259	Doxx family
A388_RS00800	COG4399	Belongs to the UPF0754 family
A388_RS00805	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A388_RS00805	COG0519	Catalyzes the synthesis of GMP from XMP
A388_RS00850	COG0281	malic enzyme
A388_RS00855	COG2837	iron assimilation
A388_RS00860	COG1280	lysine exporter protein (LysE YggA)
A388_RS00865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
A388_RS00870	COG1121	(ABC) transporter
A388_RS00935	COG0386	Belongs to the glutathione peroxidase family
A388_RS00950	COG1309	transcriptional regulator
A388_RS00955	COG0697	spore germination
A388_RS00965	COG0758	DNA mediated transformation
A388_RS01000	COG1309	transcriptional regulator
A388_RS01035	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A388_RS01045	COG0655	NAD(P)H dehydrogenase (quinone) activity
A388_RS01080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
A388_RS01090	COG0477	Major facilitator Superfamily
A388_RS01100	COG1253	flavin adenine dinucleotide binding
A388_RS01110	COG2860	membrane
A388_RS01115	COG0477	Major facilitator Superfamily
A388_RS01125	COG0318	PFAM AMP-dependent synthetase and ligase
A388_RS01140	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
A388_RS01155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A388_RS01165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A388_RS01170	COG0606	chelatase, subunit chli
A388_RS01200	COG2072	flavoprotein involved in K transport
A388_RS01205	COG0492	ferredoxin-NADP+ reductase activity
A388_RS01210	COG0431	NADPH-dependent FMN reductase
A388_RS01215	COG0798	PFAM Bile acid sodium symporter
A388_RS01225	COG0640	Transcriptional regulator
A388_RS01240	COG0789	Transcriptional regulator
A388_RS01270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A388_RS01370	COG0789	Transcriptional regulator
A388_RS01390	COG0697	spore germination
A388_RS01460	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A388_RS01495	COG2814	Major facilitator Superfamily
A388_RS01500	COG0583	DNA-binding transcription factor activity
A388_RS01520	COG0667	Aldo Keto reductase
A388_RS01545	COG1733	regulation of RNA biosynthetic process
A388_RS01560	COG1733	regulation of RNA biosynthetic process
A388_RS01570	COG2249	NAD(P)H dehydrogenase (quinone) activity
A388_RS01580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A388_RS01640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
A388_RS01680	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A388_RS01710	COG0427	acetyl-CoA hydrolase
A388_RS01735	COG0659	secondary active sulfate transmembrane transporter activity
A388_RS01740	COG4221	oxidoreductase activity
A388_RS01745	COG2873	o-acetylhomoserine
A388_RS01750	COG0488	(ABC) transporter
A388_RS01815	COG0833	amino acid
A388_RS01860	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
A388_RS01865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
A388_RS01880	COG2226	methyltransferase
A388_RS01930	COG0070	glutamate synthase
A388_RS01930	COG0069	glutamate synthase activity
A388_RS01930	COG0067	glutamate synthase
A388_RS01935	COG0493	'glutamate synthase
A388_RS01945	COG1704	LemA family
A388_RS01950	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
A388_RS01965	COG3307	-O-antigen
A388_RS01985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A388_RS01995	COG0194	GDP metabolic process
A388_RS02045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
A388_RS02065	COG5380	lipid catabolic process
A388_RS02070	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A388_RS02095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A388_RS02100	COG0277	FAD linked oxidase domain protein
A388_RS02110	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
A388_RS02115	COG2249	NAD(P)H dehydrogenase (quinone) activity
A388_RS02130	COG1289	transmembrane transporter activity
A388_RS02140	COG0628	permease
A388_RS02145	COG1192	Involved in chromosome partitioning
A388_RS02175	COG0833	amino acid
A388_RS02180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A388_RS02185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A388_RS02195	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS02235	COG0583	DNA-binding transcription factor activity
A388_RS02285	COG0517	IMP dehydrogenase activity
A388_RS02290	COG1983	PspC domain protein
A388_RS02300	COG1960	acyl-CoA dehydrogenase activity
A388_RS02315	COG0408	coproporphyrinogen oxidase activity
A388_RS02335	COG0513	Belongs to the DEAD box helicase family
A388_RS02340	COG1127	ABC transporter
A388_RS02345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
A388_RS02355	COG2854	intermembrane phospholipid transfer
A388_RS02365	COG0598	Magnesium transport protein CorA
A388_RS02375	COG0494	nUDIX hydrolase
A388_RS02380	COG1040	competence protein
A388_RS02385	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
A388_RS02405	COG1946	Acyl-CoA thioesterase
A388_RS02410	COG1301	dicarboxylic acid transport
A388_RS02425	COG1959	2 iron, 2 sulfur cluster binding
A388_RS02430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A388_RS02430	COG1017	nitric oxide dioxygenase activity
A388_RS02435	COG0433	COG0433 Predicted ATPase
A388_RS02440	COG0626	cystathionine gamma-synthase activity
A388_RS02595	COG1960	acyl-CoA dehydrogenase activity
A388_RS02600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
A388_RS02630	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
A388_RS02635	COG0339	signal peptide processing
A388_RS02640	COG0557	exoribonuclease II activity
A388_RS02665	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS02690	COG0179	Fumarylacetoacetate (FAA) hydrolase
A388_RS02695	COG2169	Transcriptional regulator
A388_RS02700	COG0697	spore germination
A388_RS02705	COG1295	ribonuclease BN
A388_RS02740	COG1702	phosphate starvation-inducible protein PhoH
A388_RS02750	COG1196	nuclear chromosome segregation
A388_RS02750	COG0739	heme binding
A388_RS02750	COG0741	lytic transglycosylase activity
A388_RS02780	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
A388_RS02785	COG1183	phosphatidylcholine synthase activity
A388_RS02830	COG1960	acyl-CoA dehydrogenase activity
A388_RS02835	COG1309	transcriptional regulator
A388_RS02850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A388_RS02855	COG1960	acyl-CoA dehydrogenase activity
A388_RS02875	COG2969	positive regulation of protein catabolic process
A388_RS02885	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A388_RS02900	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A388_RS02905	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
A388_RS02925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A388_RS02935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A388_RS02940	COG1408	metallophosphoesterase
A388_RS02950	COG2199	diguanylate cyclase activity
A388_RS03010	COG1607	acyl-coa hydrolase
A388_RS03040	COG2350	Protein conserved in bacteria
A388_RS03050	COG0613	PHP domain protein
A388_RS03055	COG3781	membrane
A388_RS03065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
A388_RS03080	COG1862	Preprotein translocase
A388_RS03130	COG0629	single-stranded DNA binding
A388_RS03330	COG4695	Portal protein
A388_RS03335	COG2205	protein histidine kinase activity
A388_RS03340	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
A388_RS03360	COG0726	polysaccharide deacetylase
A388_RS03365	COG0463	Glycosyl transferase, family 2
A388_RS03370	COG0438	transferase activity, transferring glycosyl groups
A388_RS03435	COG1960	acyl-CoA dehydrogenase activity
A388_RS03440	COG1960	acyl-CoA dehydrogenase activity
A388_RS03450	COG2205	protein histidine kinase activity
A388_RS03455	COG0745	RESPONSE REGULATOR receiver
A388_RS03460	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
A388_RS03480	COG2096	Adenosyltransferase
A388_RS03485	COG4206	TonB-dependent receptor
A388_RS03530	COG0285	dihydrofolate synthase activity
A388_RS03550	COG0450	alkyl hydroperoxide reductase
A388_RS03565	COG0477	Major facilitator Superfamily
A388_RS03570	COG1272	protein, Hemolysin III
A388_RS03600	COG0183	Belongs to the thiolase family
A388_RS03605	COG2207	Transcriptional regulator
A388_RS03625	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A388_RS03645	COG0183	Belongs to the thiolase family
A388_RS03655	COG2885	chlorophyll binding
A388_RS03655	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
A388_RS03660	COG1690	Belongs to the RtcB family
A388_RS03665	COG0833	amino acid
A388_RS03675	COG2233	PERMEase
A388_RS03680	COG1217	gtp-binding protein TYPA
A388_RS03705	COG2094	Belongs to the DNA glycosylase MPG family
A388_RS03710	COG4772	TonB-dependent receptor
A388_RS03715	COG1902	pentaerythritol trinitrate reductase activity
A388_RS03720	COG0679	Auxin Efflux Carrier
A388_RS03730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A388_RS03735	COG0354	folic acid binding
A388_RS03745	COG3189	MarR family transcriptional regulator
A388_RS03750	COG2824	Alkylphosphonate utilization operon protein PhnA
A388_RS03755	COG3422	double-strand break repair
A388_RS03795	COG0840	transmembrane signaling receptor activity
A388_RS03810	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A388_RS03825	COG5510	response to toxic substance
A388_RS03835	COG2832	Protein of unknown function (DUF454)
A388_RS03840	COG1376	ErfK ybiS ycfS ynhG family protein
A388_RS03880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
A388_RS03890	COG1289	transmembrane transporter activity
A388_RS03895	COG2814	Major facilitator Superfamily
A388_RS03915	COG1115	amino acid carrier protein
A388_RS03920	COG1752	Esterase of the alpha-beta hydrolase superfamily
A388_RS03925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A388_RS03930	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
A388_RS03955	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A388_RS03965	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A388_RS03970	COG1077	Cell shape determining protein MreB Mrl
A388_RS03975	COG1792	Involved in formation and maintenance of cell shape
A388_RS03980	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
A388_RS03985	COG0424	maF-like protein
A388_RS03990	COG1530	ribonuclease E activity
A388_RS04000	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A388_RS04010	COG0560	Phosphoserine phosphatase
A388_RS04020	COG2249	NAD(P)H dehydrogenase (quinone) activity
A388_RS04045	COG2207	Transcriptional regulator
A388_RS04355	COG0741	lytic transglycosylase activity
A388_RS04355	COG0739	heme binding
A388_RS04355	COG1196	nuclear chromosome segregation
A388_RS04415	COG0582	viral genome integration into host DNA
A388_RS04425	COG1113	amino acid transport
A388_RS04430	COG2828	Protein conserved in bacteria
A388_RS04435	COG0142	geranyltranstransferase activity
A388_RS04440	COG2315	Protein conserved in bacteria
A388_RS04455	COG1752	Esterase of the alpha-beta hydrolase superfamily
A388_RS04475	COG2194	sulfuric ester hydrolase activity
A388_RS04480	COG0745	RESPONSE REGULATOR receiver
A388_RS04485	COG0642	Histidine kinase
A388_RS04495	COG0004	ammonium transporteR
A388_RS04505	COG0583	DNA-binding transcription factor activity
A388_RS04525	COG0525	valine-tRNA ligase activity
A388_RS04535	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS04545	COG0393	Putative heavy-metal-binding
A388_RS04550	COG0393	Putative heavy-metal-binding
A388_RS04555	COG1538	Outer membrane efflux protein
A388_RS04575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS04580	COG0671	phosphoesterase, PA-phosphatase related
A388_RS04610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
A388_RS04625	COG1648	precorrin-2 dehydrogenase activity
A388_RS04625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
A388_RS04630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
A388_RS04635	COG1733	regulation of RNA biosynthetic process
A388_RS04645	COG0531	amino acid
A388_RS04660	COG0321	lipoyl(octanoyl) transferase activity
A388_RS04665	COG2921	Belongs to the UPF0250 family
A388_RS04700	COG2009	succinate dehydrogenase
A388_RS04705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
A388_RS04710	COG1053	succinate dehydrogenase
A388_RS04715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
A388_RS04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A388_RS04770	COG2354	Protein conserved in bacteria
A388_RS04775	COG2321	neutral zinc metallopeptidase
A388_RS04800	COG2843	Capsule synthesis protein
A388_RS04815	COG0589	response to stress
A388_RS04835	COG0505	Belongs to the CarA family
A388_RS04860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A388_RS04865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A388_RS04920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
A388_RS04935	COG1597	lipid kinase activity
A388_RS04940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A388_RS04965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A388_RS04970	COG0584	glycerophosphoryl diester phosphodiesterase
A388_RS04990	COG0741	lytic transglycosylase activity
A388_RS05015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
A388_RS05030	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A388_RS05075	COG0778	Nitroreductase
A388_RS05090	COG1929	Belongs to the glycerate kinase type-1 family
A388_RS05095	COG0243	molybdopterin cofactor binding
A388_RS05100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A388_RS05105	COG3339	Conserved Protein
A388_RS05115	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
A388_RS05130	COG1113	amino acid transport
A388_RS05140	COG0019	diaminopimelate decarboxylase activity
A388_RS05150	COG2267	carboxylic ester hydrolase activity
A388_RS05155	COG1280	lysine exporter protein (LysE YggA)
A388_RS05160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
A388_RS05190	COG0463	Glycosyl transferase, family 2
A388_RS05210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS05240	COG4591	ABC-type transport system involved in lipoprotein release permease component
A388_RS05245	COG1136	(ABC) transporter
A388_RS05250	COG0658	competence protein
A388_RS05250	COG2333	competence protein COMEC
A388_RS05260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
A388_RS05260	COG0616	signal peptide processing
A388_RS05265	COG0596	Alpha beta hydrolase
A388_RS05270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
A388_RS05280	COG0628	permease
A388_RS05315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A388_RS05335	COG0823	Involved in the tonB-independent uptake of proteins
A388_RS05355	COG0824	Thioesterase
A388_RS05360	COG1473	amidohydrolase
A388_RS05380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A388_RS05380	COG0047	phosphoribosylformylglycinamidine synthase activity
A388_RS05385	COG2814	Major facilitator Superfamily
A388_RS05395	COG1024	Enoyl-CoA hydratase
A388_RS05400	COG1051	belongs to the nudix hydrolase family
A388_RS05400	COG1056	cytidyltransferase-related domain
A388_RS05410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A388_RS05425	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A388_RS05440	COG4625	pathogenesis
A388_RS05445	COG0583	DNA-binding transcription factor activity
A388_RS05450	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
A388_RS05455	COG4208	sulfate ABC transporter
A388_RS05460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A388_RS05470	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
A388_RS05475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
A388_RS05480	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
A388_RS05500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A388_RS05515	COG0681	Belongs to the peptidase S26 family
A388_RS05530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
A388_RS05540	COG1381	Involved in DNA repair and RecF pathway recombination
A388_RS05545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
A388_RS05555	COG4221	oxidoreductase activity
A388_RS05585	COG0436	Aminotransferase
A388_RS05605	COG0556	nucleotide-excision repair
A388_RS05660	COG2070	2-Nitropropane dioxygenase
A388_RS05690	COG1215	transferase activity, transferring glycosyl groups
A388_RS05705	COG0415	Belongs to the DNA photolyase family
A388_RS05715	COG1252	NADH dehydrogenase
A388_RS05720	COG1686	Belongs to the peptidase S11 family
A388_RS05735	COG1187	pseudouridine synthase activity
A388_RS05760	COG0477	Major facilitator Superfamily
A388_RS05765	COG0583	DNA-binding transcription factor activity
A388_RS05770	COG1823	symporter activity
A388_RS05780	COG0612	Peptidase, M16
A388_RS05810	COG1203	CRISPR-associated helicase, Cas3
A388_RS05835	COG0352	thiamine-phosphate diphosphorylase activity
A388_RS05870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A388_RS05885	COG1309	transcriptional regulator
A388_RS05895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A388_RS05900	COG0076	glutamate decarboxylase activity
A388_RS05910	COG1522	sequence-specific DNA binding
A388_RS05915	COG3961	Belongs to the TPP enzyme family
A388_RS05920	COG1113	amino acid transport
A388_RS05925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
A388_RS05930	COG0573	inorganic phosphate transmembrane transporter activity
A388_RS05940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A388_RS05945	COG0616	signal peptide processing
A388_RS05980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
A388_RS05985	COG1686	Belongs to the peptidase S11 family
A388_RS06010	COG0583	DNA-binding transcription factor activity
A388_RS06015	COG1067	ATP-dependent peptidase activity
A388_RS06040	COG4943	cyclic-guanylate-specific phosphodiesterase activity
A388_RS06060	COG1966	Carbon starvation protein
A388_RS06065	COG2879	small protein
A388_RS06075	COG0583	DNA-binding transcription factor activity
A388_RS06080	COG0006	proline dipeptidase activity
A388_RS06085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A388_RS06090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A388_RS06100	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS06105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A388_RS06110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A388_RS06110	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
A388_RS06170	COG1741	Belongs to the pirin family
A388_RS06180	COG2964	Protein conserved in bacteria
A388_RS06195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A388_RS06200	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A388_RS06205	COG4605	iron ion homeostasis
A388_RS06210	COG4604	ABC transporter, ATP-binding protein
A388_RS06215	COG4607	ABC-type enterochelin transport system periplasmic component
A388_RS06220	COG4774	siderophore transport
A388_RS06230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
A388_RS06235	COG1021	2,3-dihydroxybenzoate-AMP ligase
A388_RS06240	COG3433	isochorismatase activity
A388_RS06240	COG1535	isochorismatase
A388_RS06255	COG1132	(ABC) transporter
A388_RS06260	COG1132	(ABC) transporter
A388_RS06265	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
A388_RS06275	COG1169	isochorismate synthase
A388_RS06290	COG3739	integral membrane protein
A388_RS06310	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS06315	COG0302	gtp cyclohydrolase
A388_RS06325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
A388_RS06355	COG0308	aminopeptidase N
A388_RS06360	COG0512	Glutamine amidotransferase of anthranilate synthase
A388_RS06375	COG0174	glutamine synthetase
A388_RS06385	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A388_RS06420	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
A388_RS06425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A388_RS06430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A388_RS06450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A388_RS06455	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
A388_RS06460	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A388_RS06475	COG1960	acyl-CoA dehydrogenase activity
A388_RS06480	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A388_RS06485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A388_RS06495	COG2223	nitrite transmembrane transporter activity
A388_RS06505	COG0024	Methionine aminopeptidase
A388_RS06510	COG0052	Belongs to the universal ribosomal protein uS2 family
A388_RS06525	COG2207	Transcriptional regulator
A388_RS06550	COG2951	lytic endotransglycosylase activity
A388_RS06555	COG0772	Belongs to the SEDS family
A388_RS06570	COG0842	Transport permease protein
A388_RS06575	COG1131	(ABC) transporter
A388_RS06580	COG0582	viral genome integration into host DNA
A388_RS06675	COG0305	Participates in initiation and elongation during chromosome replication
A388_RS06775	COG5410	chromosome segregation
A388_RS06885	COG3561	AntA/AntB antirepressor
A388_RS07010	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS07025	COG4215	(ABC) transporter
A388_RS07030	COG4160	amino acid transport
A388_RS07035	COG4598	ABC transporter
A388_RS07045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A388_RS07050	COG0826	peptidase U32
A388_RS07055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A388_RS07070	COG1720	tRNA m6t6A37 methyltransferase activity
A388_RS07080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
A388_RS07095	COG0642	Histidine kinase
A388_RS07105	COG0494	nUDIX hydrolase
A388_RS07115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
A388_RS07120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A388_RS07125	COG3139	Protein of unknown function (DUF1315)
A388_RS07130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
A388_RS07140	COG1301	dicarboxylic acid transport
A388_RS07145	COG1960	acyl-CoA dehydrogenase activity
A388_RS07150	COG2819	hydrolase of the alpha beta superfamily
A388_RS07160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A388_RS07170	COG2195	Cleaves the N-terminal amino acid of tripeptides
A388_RS07175	COG1234	tRNA 3'-trailer cleavage
A388_RS07200	COG2363	Small membrane protein
A388_RS07220	COG0513	Belongs to the DEAD box helicase family
A388_RS07230	COG0778	Nitroreductase
A388_RS07260	COG1286	toxin biosynthetic process
A388_RS07285	COG4783	chaperone-mediated protein folding
A388_RS07290	COG1610	YqeY-like protein
A388_RS07370	COG2995	paraquat-inducible protein a
A388_RS07375	COG3008	intermembrane lipid transfer
A388_RS07375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
A388_RS07385	COG2351	hydroxyisourate hydrolase activity
A388_RS07425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A388_RS07435	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
A388_RS07440	COG0642	Histidine kinase
A388_RS07445	COG0745	RESPONSE REGULATOR receiver
A388_RS07465	COG1794	racemase activity, acting on amino acids and derivatives
A388_RS07495	COG1301	dicarboxylic acid transport
A388_RS07505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A388_RS07510	COG2011	ABC-type metal ion transport system permease component
A388_RS07515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
A388_RS07520	COG1464	Belongs to the NlpA lipoprotein family
A388_RS07525	COG0151	Belongs to the GarS family
A388_RS07530	COG0138	bifunctional purine biosynthesis protein purh
A388_RS07535	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
A388_RS07565	COG2308	Evidence 4 Homologs of previously reported genes of
A388_RS07575	COG1305	Transglutaminase-like
A388_RS07585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
A388_RS07590	COG0305	Participates in initiation and elongation during chromosome replication
A388_RS07615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
A388_RS07625	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
A388_RS07630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
A388_RS07655	COG1649	PFAM Uncharacterised BCR, COG1649
A388_RS07655	COG0726	polysaccharide deacetylase
A388_RS07660	COG1215	transferase activity, transferring glycosyl groups
A388_RS07665	COG3658	cytochrome
A388_RS07675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A388_RS07695	COG0583	DNA-binding transcription factor activity
A388_RS07715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A388_RS07720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A388_RS07735	COG1960	acyl-CoA dehydrogenase activity
A388_RS07740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A388_RS07745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS07770	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
A388_RS07775	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
A388_RS07785	COG2205	protein histidine kinase activity
A388_RS07790	COG0745	RESPONSE REGULATOR receiver
A388_RS07795	COG0174	glutamine synthetase
A388_RS07815	COG0729	surface antigen
A388_RS07845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A388_RS07850	COG2814	Major facilitator Superfamily
A388_RS07865	COG0583	DNA-binding transcription factor activity
A388_RS07880	COG1187	pseudouridine synthase activity
A388_RS07900	COG0802	atpase or kinase
A388_RS07905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
A388_RS07915	COG1923	regulation of RNA biosynthetic process
A388_RS07920	COG0697	spore germination
A388_RS07945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A388_RS07950	COG0519	Catalyzes the synthesis of GMP from XMP
A388_RS07950	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A388_RS07955	COG4302	ethanolamine ammonia-lyase activity
A388_RS07960	COG4303	Ethanolamine ammonia lyase large subunit
A388_RS07965	COG0531	amino acid
A388_RS07985	COG1454	alcohol dehydrogenase
A388_RS07990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A388_RS08015	COG0308	aminopeptidase N
A388_RS08055	COG1605	Chorismate mutase
A388_RS08075	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
A388_RS08085	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS08100	COG1309	transcriptional regulator
A388_RS08110	COG0668	transmembrane transport
A388_RS08140	COG4773	Receptor
A388_RS08160	COG0488	(ABC) transporter
A388_RS08165	COG0589	response to stress
A388_RS08185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
A388_RS08195	COG3135	benzoate transporter
A388_RS08200	COG1522	sequence-specific DNA binding
A388_RS08210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
A388_RS08215	COG0583	DNA-binding transcription factor activity
A388_RS08225	COG0183	Belongs to the thiolase family
A388_RS08235	COG2030	dehydratase
A388_RS08240	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A388_RS08255	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
A388_RS08265	COG0824	Thioesterase
A388_RS08270	COG1454	alcohol dehydrogenase
A388_RS08280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
A388_RS08300	COG0069	glutamate synthase activity
A388_RS08320	COG2814	Major facilitator Superfamily
A388_RS08335	COG0511	ligase activity, forming carbon-carbon bonds
A388_RS08355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
A388_RS08355	COG1116	anion transmembrane transporter activity
A388_RS08360	COG0745	RESPONSE REGULATOR receiver
A388_RS08370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A388_RS08370	COG2146	nitrite reductase [NAD(P)H] activity
A388_RS08375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A388_RS08380	COG0243	molybdopterin cofactor binding
A388_RS08390	COG0243	molybdopterin cofactor binding
A388_RS08395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A388_RS08410	COG0521	Mo-molybdopterin cofactor biosynthetic process
A388_RS08410	COG0315	cyclic pyranopterin monophosphate synthase activity
A388_RS08415	COG0303	'Molybdopterin
A388_RS08430	COG0697	spore germination
A388_RS08450	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
A388_RS08455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
A388_RS08515	COG2204	response regulator
A388_RS08520	COG3852	Histidine kinase
A388_RS08545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A388_RS08550	COG0575	Belongs to the CDS family
A388_RS08585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A388_RS08600	COG2137	regulation of response to DNA damage stimulus
A388_RS08610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
A388_RS08615	COG1011	Hydrolase
A388_RS08640	COG1522	sequence-specific DNA binding
A388_RS08650	COG1113	amino acid transport
A388_RS08670	COG0659	secondary active sulfate transmembrane transporter activity
A388_RS08675	COG2135	peptidase activity
A388_RS08690	COG5001	Diguanylate cyclase
A388_RS08690	COG3300	MHYT domain
A388_RS08715	COG1105	Belongs to the carbohydrate kinase PfkB family
A388_RS08720	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A388_RS08720	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
A388_RS08750	COG0024	Methionine aminopeptidase
A388_RS08755	COG0583	DNA-binding transcription factor activity
A388_RS08765	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
A388_RS08770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
A388_RS08775	COG0517	IMP dehydrogenase activity
A388_RS08775	COG0516	GMP reductase activity
A388_RS08800	COG0552	protein localization to endoplasmic reticulum
A388_RS08810	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
A388_RS08820	COG4890	Cyd operon protein YbgT
A388_RS08825	COG1294	oxidase, subunit
A388_RS08845	COG1585	Membrane protein implicated in regulation of membrane protease activity
A388_RS08855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A388_RS08860	COG4774	siderophore transport
A388_RS08875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A388_RS08880	COG0569	domain protein
A388_RS08885	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
A388_RS08915	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
A388_RS08920	COG0542	response to heat
A388_RS08945	COG1902	pentaerythritol trinitrate reductase activity
A388_RS08945	COG0446	pyridine nucleotide-disulphide oxidoreductase
A388_RS08990	COG2323	membrane
A388_RS08995	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
A388_RS09005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A388_RS09010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A388_RS09015	COG0183	Belongs to the thiolase family
A388_RS09020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A388_RS09025	COG0596	Alpha beta hydrolase
A388_RS09030	COG2271	Major facilitator Superfamily
A388_RS09035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A388_RS09040	COG3485	protocatechuate 3,4-dioxygenase
A388_RS09045	COG3485	protocatechuate 3,4-dioxygenase
A388_RS09050	COG0710	3-dehydroquinate dehydratase activity
A388_RS09055	COG3420	alginic acid biosynthetic process
A388_RS09060	COG3659	wide pore channel activity
A388_RS09065	COG4993	Dehydrogenase
A388_RS09075	COG2391	methyltransferase activity
A388_RS09090	COG1414	Transcriptional regulator
A388_RS09095	COG0583	DNA-binding transcription factor activity
A388_RS09100	COG1960	acyl-CoA dehydrogenase activity
A388_RS09125	COG2814	Major facilitator Superfamily
A388_RS09135	COG0154	amidase activity
A388_RS09155	COG4638	Rieske (2fe-2S)
A388_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS09175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS09185	COG3733	amine oxidase
A388_RS09195	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS09205	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A388_RS09210	COG0183	Belongs to the thiolase family
A388_RS09220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A388_RS09225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A388_RS09235	COG4829	muconolactone delta-isomerase
A388_RS09240	COG4948	Mandelate Racemase Muconate Lactonizing
A388_RS09245	COG0583	DNA-binding transcription factor activity
A388_RS09255	COG2186	Transcriptional regulator
A388_RS09275	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS09290	COG0446	pyridine nucleotide-disulphide oxidoreductase
A388_RS09290	COG1902	pentaerythritol trinitrate reductase activity
A388_RS09330	COG1309	transcriptional regulator
A388_RS09345	COG4689	acetoacetate decarboxylase
A388_RS09355	COG1902	pentaerythritol trinitrate reductase activity
A388_RS09375	COG1335	isochorismatase
A388_RS09380	COG0583	DNA-binding transcription factor activity
A388_RS09390	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A388_RS09390	COG0475	glutathione-regulated potassium exporter activity
A388_RS09400	COG1473	amidohydrolase
A388_RS09425	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS09485	COG2188	Transcriptional regulator
A388_RS09500	COG0583	DNA-binding transcription factor activity
A388_RS09515	COG1566	PFAM secretion protein HlyD family protein
A388_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS09540	COG0129	dihydroxy-acid dehydratase activity
A388_RS09550	COG0583	DNA-binding transcription factor activity
A388_RS09555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A388_RS09565	COG2084	Dehydrogenase
A388_RS09580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A388_RS09625	COG1073	alpha beta
A388_RS09635	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS09650	COG2207	Transcriptional regulator
A388_RS09660	COG2205	protein histidine kinase activity
A388_RS09665	COG0745	RESPONSE REGULATOR receiver
A388_RS09670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS09675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A388_RS09680	COG1538	Outer membrane efflux protein
A388_RS09690	COG2072	flavoprotein involved in K transport
A388_RS09700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A388_RS09900	COG3539	Fimbrial protein
A388_RS09925	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
A388_RS09935	COG0753	catalase activity
A388_RS09950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
A388_RS10015	COG3433	isochorismatase activity
A388_RS10015	COG1535	isochorismatase
A388_RS10020	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS10025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A388_RS10030	COG4149	molybdate abc transporter
A388_RS10035	COG0725	ABC transporter, periplasmic molybdate-binding protein
A388_RS10045	COG4638	Rieske (2fe-2S)
A388_RS10050	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A388_RS10055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A388_RS10055	COG0543	2 iron, 2 sulfur cluster binding
A388_RS10070	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS10080	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS10095	COG2207	Transcriptional regulator
A388_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS10105	COG2610	gluconate transmembrane transporter activity
A388_RS10115	COG0583	DNA-binding transcription factor activity
A388_RS10130	COG2031	fatty acid transporter
A388_RS10135	COG0183	Belongs to the thiolase family
A388_RS10140	COG0583	DNA-binding transcription factor activity
A388_RS10145	COG0583	DNA-binding transcription factor activity
A388_RS10160	COG1027	Aspartate ammonia-lyase
A388_RS10170	COG0477	Major facilitator Superfamily
A388_RS10190	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A388_RS10195	COG4521	taurine ABC transporter
A388_RS10210	COG2188	Transcriptional regulator
A388_RS10220	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
A388_RS10225	COG1733	regulation of RNA biosynthetic process
A388_RS10230	COG3708	Transcriptional regulator
A388_RS10230	COG2207	Transcriptional regulator
A388_RS10245	COG0730	response to heat
A388_RS10255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A388_RS10255	COG3453	Protein conserved in bacteria
A388_RS10265	COG3781	membrane
A388_RS10270	COG1063	alcohol dehydrogenase
A388_RS10280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
A388_RS10285	COG0508	dehydrogenase complex catalyzes the overall conversion of
A388_RS10290	COG0022	dehydrogenase e1 component
A388_RS10295	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
A388_RS10300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
A388_RS10315	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS10325	COG3706	GGDEF domain
A388_RS10340	COG0133	tryptophan synthase activity
A388_RS10350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A388_RS10385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
A388_RS10410	COG2226	methyltransferase
A388_RS10465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
A388_RS10490	COG0730	response to heat
A388_RS10495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
A388_RS10510	COG0406	alpha-ribazole phosphatase activity
A388_RS10515	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
A388_RS10530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A388_RS10560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A388_RS10570	COG4264	IucA IucC family
A388_RS10575	COG4264	IucA IucC family
A388_RS10580	COG2814	Major facilitator Superfamily
A388_RS10595	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
A388_RS10610	COG1960	acyl-CoA dehydrogenase activity
A388_RS10615	COG1960	acyl-CoA dehydrogenase activity
A388_RS10620	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
A388_RS10625	COG2207	Transcriptional regulator
A388_RS10630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A388_RS10635	COG0776	regulation of translation
A388_RS10660	COG0822	iron-sulfur transferase activity
A388_RS10665	COG0316	Belongs to the HesB IscA family
A388_RS10695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
A388_RS10715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
A388_RS10720	COG0702	epimerase
A388_RS10755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A388_RS10765	COG0339	signal peptide processing
A388_RS10785	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
A388_RS10810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
A388_RS10815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
A388_RS10845	COG0776	regulation of translation
A388_RS10910	COG0084	hydrolase, TatD family'
A388_RS10930	COG1663	tetraacyldisaccharide 4'-kinase activity
A388_RS10935	COG1132	(ABC) transporter
A388_RS10945	COG0811	peptide transport
A388_RS10950	COG1475	DNA binding
A388_RS10955	COG1192	Involved in chromosome partitioning
A388_RS10965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
A388_RS10980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
A388_RS10985	COG0191	fructose-bisphosphate aldolase activity
A388_RS11005	COG0424	maF-like protein
A388_RS11010	COG2850	peptidyl-arginine hydroxylation
A388_RS11020	COG0640	Transcriptional regulator
A388_RS11030	COG3619	membrane
A388_RS11035	COG3122	Protein conserved in bacteria
A388_RS11040	COG1132	(ABC) transporter
A388_RS11060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A388_RS11065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A388_RS11075	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A388_RS11075	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
A388_RS11075	COG0506	proline dehydrogenase activity
A388_RS11080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
A388_RS11095	COG3698	Phosphodiester glycosidase
A388_RS11105	COG2353	YceI-like domain
A388_RS11115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
A388_RS11160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
A388_RS11160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
A388_RS11185	COG3539	Fimbrial protein
A388_RS11190	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS11200	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS11205	COG3121	Chaperone
A388_RS11235	COG0697	spore germination
A388_RS11255	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A388_RS11265	COG0583	DNA-binding transcription factor activity
A388_RS11285	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS11290	COG1309	transcriptional regulator
A388_RS11305	COG1522	sequence-specific DNA binding
A388_RS11315	COG1126	abc transporter atp-binding protein
A388_RS11320	COG0765	amino acid transport
A388_RS11325	COG0765	amino acid transport
A388_RS11355	COG1464	Belongs to the NlpA lipoprotein family
A388_RS11380	COG2011	ABC-type metal ion transport system permease component
A388_RS11385	COG0012	GTP binding
A388_RS11410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A388_RS11450	COG0386	Belongs to the glutathione peroxidase family
A388_RS11460	COG0436	Aminotransferase
A388_RS11465	COG1301	dicarboxylic acid transport
A388_RS11500	COG3634	alkyl hydroperoxide reductase activity
A388_RS11515	COG0583	DNA-binding transcription factor activity
A388_RS11520	COG0798	PFAM Bile acid sodium symporter
A388_RS11525	COG0640	Transcriptional regulator
A388_RS11540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
A388_RS11550	COG0583	DNA-binding transcription factor activity
A388_RS11560	COG1953	Uracil, thiamine, allantoin
A388_RS11570	COG2175	clavaminate synthase activity
A388_RS11575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
A388_RS11580	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
A388_RS11585	COG4521	taurine ABC transporter
A388_RS11605	COG0477	Major facilitator Superfamily
A388_RS11630	COG1271	oxidase subunit
A388_RS11635	COG1294	oxidase, subunit
A388_RS11645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A388_RS11665	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
A388_RS11685	COG3052	prosthetic group binding
A388_RS11690	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
A388_RS11700	COG2814	Major facilitator Superfamily
A388_RS11715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A388_RS11720	COG1346	cytolysis
A388_RS11730	COG0583	DNA-binding transcription factor activity
A388_RS11735	COG0625	glutathione transferase activity
A388_RS11740	COG0625	glutathione transferase activity
A388_RS11745	COG0583	DNA-binding transcription factor activity
A388_RS11760	COG1045	serine acetyltransferase
A388_RS11765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A388_RS11770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A388_RS11775	COG1280	lysine exporter protein (LysE YggA)
A388_RS11785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A388_RS11790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A388_RS11795	COG1126	abc transporter atp-binding protein
A388_RS11800	COG0765	amino acid transport
A388_RS11805	COG0765	amino acid transport
A388_RS11825	COG2205	protein histidine kinase activity
A388_RS11825	COG0784	Response regulator, receiver
A388_RS11865	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS11910	COG0583	DNA-binding transcription factor activity
A388_RS11930	COG0318	PFAM AMP-dependent synthetase and ligase
A388_RS11935	COG1309	transcriptional regulator
A388_RS11940	COG1960	acyl-CoA dehydrogenase activity
A388_RS11945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A388_RS11950	COG1024	Enoyl-CoA hydratase
A388_RS11955	COG4770	biotin carboxylase activity
A388_RS11965	COG0583	DNA-binding transcription factor activity
A388_RS11980	COG1960	acyl-CoA dehydrogenase activity
A388_RS11990	COG2814	Major facilitator Superfamily
A388_RS12000	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
A388_RS12005	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
A388_RS12010	COG2814	Major facilitator Superfamily
A388_RS12015	COG1960	acyl-CoA dehydrogenase activity
A388_RS12020	COG1024	Enoyl-CoA hydratase
A388_RS12025	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS12030	COG1250	3-hydroxyacyl-CoA dehydrogenase
A388_RS12035	COG0183	Belongs to the thiolase family
A388_RS12045	COG2814	Major facilitator Superfamily
A388_RS12055	COG1024	Enoyl-CoA hydratase
A388_RS12065	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A388_RS12070	COG1960	acyl-CoA dehydrogenase activity
A388_RS12075	COG2814	Major facilitator Superfamily
A388_RS12080	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
A388_RS12085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A388_RS12100	COG3842	ATPase activity
A388_RS12105	COG1840	ABC-type Fe3 transport system, periplasmic component
A388_RS12115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A388_RS12120	COG1414	Transcriptional regulator
A388_RS12130	COG0583	DNA-binding transcription factor activity
A388_RS12135	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
A388_RS12140	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS12150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
A388_RS12160	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS12165	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
A388_RS12170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS12175	COG2267	carboxylic ester hydrolase activity
A388_RS12195	COG3038	cytochrome b561
A388_RS12200	COG0753	catalase activity
A388_RS12205	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS12210	COG2271	Major facilitator Superfamily
A388_RS12215	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A388_RS12220	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A388_RS12250	COG1278	Cold shock
A388_RS12290	COG0210	DNA helicase
A388_RS12295	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
A388_RS12300	COG2050	protein possibly involved in aromatic compounds catabolism
A388_RS12310	COG3327	negative regulation of DNA-templated transcription, initiation
A388_RS12315	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
A388_RS12320	COG0183	Belongs to the thiolase family
A388_RS12325	COG1250	3-hydroxyacyl-CoA dehydrogenase
A388_RS12330	COG1024	Enoyl-CoA hydratase
A388_RS12335	COG1024	Enoyl-CoA hydratase
A388_RS12340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A388_RS12345	COG2151	metal-sulfur cluster biosynthetic enzyme
A388_RS12350	COG3396	Phenylacetate-CoA oxygenase
A388_RS12355	COG3460	Phenylacetate-CoA oxygenase
A388_RS12360	COG3396	Phenylacetate-CoA oxygenase
A388_RS12365	COG2030	dehydratase
A388_RS12365	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS12370	COG1760	l-serine dehydratase
A388_RS12375	COG0531	amino acid
A388_RS12380	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS12405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A388_RS12425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A388_RS12440	COG0789	Transcriptional regulator
A388_RS12450	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
A388_RS12465	COG2807	transmembrane transport
A388_RS12470	COG0590	tRNA wobble adenosine to inosine editing
A388_RS12565	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS12600	COG1116	anion transmembrane transporter activity
A388_RS12605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
A388_RS12615	COG0864	Transcriptional regulator
A388_RS12625	COG1733	regulation of RNA biosynthetic process
A388_RS12630	COG2249	NAD(P)H dehydrogenase (quinone) activity
A388_RS12635	COG0439	Biotin carboxylase
A388_RS12650	COG1063	alcohol dehydrogenase
A388_RS12660	COG1309	transcriptional regulator
A388_RS12690	COG0038	chloride channel
A388_RS12695	COG4770	biotin carboxylase activity
A388_RS12715	COG1914	H( )-stimulated, divalent metal cation uptake system
A388_RS12720	COG0583	DNA-binding transcription factor activity
A388_RS12740	COG3209	COG3209 Rhs family protein
A388_RS12790	COG1250	3-hydroxyacyl-CoA dehydrogenase
A388_RS12810	COG2814	Major facilitator Superfamily
A388_RS12835	COG1560	Kdo2-lipid A biosynthetic process
A388_RS12845	COG5006	permease, DMT superfamily
A388_RS12850	COG1522	sequence-specific DNA binding
A388_RS12865	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
A388_RS12875	COG4122	O-methyltransferase activity
A388_RS12905	COG1538	Outer membrane efflux protein
A388_RS12910	COG1137	ATPase activity
A388_RS12915	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
A388_RS12925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
A388_RS12980	COG5434	Belongs to the glycosyl hydrolase 28 family
A388_RS13000	COG3566	protein conserved in bacteria
A388_RS13020	COG3567	Phage-associated protein, HI1409 family
A388_RS13025	COG5410	chromosome segregation
A388_RS13100	COG2814	Major facilitator Superfamily
A388_RS13145	COG1278	Cold shock
A388_RS13150	COG1280	lysine exporter protein (LysE YggA)
A388_RS13185	COG1570	exodeoxyribonuclease VII activity
A388_RS13240	COG0583	DNA-binding transcription factor activity
A388_RS13245	COG4638	Rieske (2fe-2S)
A388_RS13250	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
A388_RS13255	COG0543	2 iron, 2 sulfur cluster binding
A388_RS13255	COG0633	Ferredoxin
A388_RS13260	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS13265	COG3135	benzoate transporter
A388_RS13270	COG2814	Major facilitator Superfamily
A388_RS13285	COG1643	Atp-dependent helicase
A388_RS13290	COG0450	alkyl hydroperoxide reductase
A388_RS13300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A388_RS13310	COG3634	alkyl hydroperoxide reductase activity
A388_RS13330	COG0220	tRNA (guanine-N7-)-methyltransferase activity
A388_RS13335	COG0625	glutathione transferase activity
A388_RS13345	COG2885	chlorophyll binding
A388_RS13380	COG0542	response to heat
A388_RS13395	COG1765	OsmC-like protein
A388_RS13405	COG2826	transposase and inactivated derivatives, IS30 family
A388_RS13410	COG0667	Aldo Keto reductase
A388_RS13425	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
A388_RS13435	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A388_RS13445	COG0582	viral genome integration into host DNA
A388_RS13535	COG0592	DNA-directed DNA polymerase activity
A388_RS13755	COG1484	DNA-dependent DNA replication
A388_RS13835	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A388_RS13875	COG0527	aspartate kinase activity
A388_RS13885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A388_RS13895	COG3038	cytochrome b561
A388_RS13900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
A388_RS13905	COG2252	PERMEase
A388_RS13915	COG2072	flavoprotein involved in K transport
A388_RS13930	COG1741	Belongs to the pirin family
A388_RS13935	COG1309	transcriptional regulator
A388_RS13945	COG0300	oxidoreductase activity
A388_RS13950	COG2072	flavoprotein involved in K transport
A388_RS13955	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
A388_RS14000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
A388_RS14015	COG2814	Major facilitator Superfamily
A388_RS14020	COG1024	Enoyl-CoA hydratase
A388_RS14025	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS14035	COG1960	acyl-CoA dehydrogenase activity
A388_RS14060	COG2186	Transcriptional regulator
A388_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS14075	COG4948	Mandelate Racemase Muconate Lactonizing
A388_RS14080	COG2271	Major facilitator Superfamily
A388_RS14085	COG2721	sulfolactate sulfo-lyase activity
A388_RS14090	COG0697	spore germination
A388_RS14120	COG1113	amino acid transport
A388_RS14140	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS14160	COG0531	amino acid
A388_RS14170	COG1113	amino acid transport
A388_RS14210	COG3209	COG3209 Rhs family protein
A388_RS14245	COG0446	pyridine nucleotide-disulphide oxidoreductase
A388_RS14245	COG1902	pentaerythritol trinitrate reductase activity
A388_RS14255	COG5001	Diguanylate cyclase
A388_RS14255	COG2203	Gaf domain
A388_RS14255	COG4251	negative regulation of phosphorylation
A388_RS14255	COG3706	GGDEF domain
A388_RS14265	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A388_RS14320	COG4172	Belongs to the ABC transporter superfamily
A388_RS14325	COG4239	(ABC) transporter, permease
A388_RS14330	COG4174	ABC transporter (Permease)
A388_RS14340	COG1388	LysM domain
A388_RS14340	COG0741	lytic transglycosylase activity
A388_RS14340	COG0741	lytic transglycosylase activity
A388_RS14340	COG1388	LysM domain
A388_RS14345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
A388_RS14385	COG0583	DNA-binding transcription factor activity
A388_RS14390	COG1279	arginine transmembrane transporter activity
A388_RS14410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A388_RS14415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A388_RS14420	COG0006	proline dipeptidase activity
A388_RS14460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
A388_RS14480	COG3384	dioxygenase
A388_RS14490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A388_RS14495	COG2878	Part of a membrane complex involved in electron transport
A388_RS14500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A388_RS14525	COG0768	penicillin binding
A388_RS14530	COG0742	ribosomal rna small subunit methyltransferase
A388_RS14545	COG0830	nickel cation binding
A388_RS14555	COG0804	urea catabolic process
A388_RS14595	COG1253	flavin adenine dinucleotide binding
A388_RS14605	COG2851	Citrate transporter
A388_RS14655	COG1773	rubredoxin
A388_RS14660	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A388_RS14670	COG0583	DNA-binding transcription factor activity
A388_RS14700	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
A388_RS14705	COG4181	ATPase activity
A388_RS14750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
A388_RS14770	COG0306	phosphate transporter
A388_RS14780	COG3958	Transketolase
A388_RS14785	COG3959	Transketolase, thiamine diphosphate binding domain
A388_RS14790	COG2271	Major facilitator Superfamily
A388_RS14795	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS14800	COG0583	DNA-binding transcription factor activity
A388_RS14820	COG2223	nitrite transmembrane transporter activity
A388_RS14825	COG2207	Transcriptional regulator
A388_RS14830	COG2066	Belongs to the glutaminase family
A388_RS14835	COG0242	peptide deformylase activity
A388_RS14840	COG0477	Major facilitator Superfamily
A388_RS14850	COG0028	Belongs to the TPP enzyme family
A388_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS14870	COG2267	carboxylic ester hydrolase activity
A388_RS14880	COG2271	Major facilitator Superfamily
A388_RS14885	COG0446	pyridine nucleotide-disulphide oxidoreductase
A388_RS14895	COG1028	Short-chain dehydrogenase reductase Sdr
A388_RS14915	COG1414	Transcriptional regulator
A388_RS14930	COG1024	Enoyl-CoA hydratase
A388_RS14940	COG1215	transferase activity, transferring glycosyl groups
A388_RS14945	COG0726	polysaccharide deacetylase
A388_RS14945	COG1649	PFAM Uncharacterised BCR, COG1649
A388_RS14955	COG4681	YaeQ
A388_RS14965	COG0523	cobalamin synthesis protein
A388_RS14975	COG1607	acyl-coa hydrolase
A388_RS14985	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A388_RS14990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A388_RS14995	COG1309	transcriptional regulator
A388_RS15020	COG2040	homocysteine
A388_RS15025	COG0531	amino acid
A388_RS15050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A388_RS15055	COG0477	Major facilitator Superfamily
A388_RS15075	COG0084	hydrolase, TatD family'
A388_RS15165	COG0582	viral genome integration into host DNA
A388_RS15175	COG0405	Gamma-glutamyltransferase
A388_RS15180	COG2814	Major facilitator Superfamily
A388_RS15190	COG2050	protein possibly involved in aromatic compounds catabolism
A388_RS15205	COG1090	epimerase
A388_RS15225	COG0420	3'-5' exonuclease activity
A388_RS15250	COG0735	belongs to the Fur family
A388_RS15255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A388_RS15280	COG0121	glutamine amidotransferase
A388_RS15295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A388_RS15305	COG0210	DNA helicase
A388_RS15310	COG2885	chlorophyll binding
A388_RS15315	COG0204	Acyl-transferase
A388_RS15330	COG2894	cell division
A388_RS15345	COG1280	lysine exporter protein (LysE YggA)
A388_RS15350	COG1674	ftsk spoiiie
A388_RS15350	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
A388_RS15355	COG0492	ferredoxin-NADP+ reductase activity
A388_RS15360	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
A388_RS15370	COG0456	acetyltransferase
A388_RS15415	COG1981	membrane
A388_RS15430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A388_RS15430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
A388_RS15450	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS15460	COG0657	acetylesterase activity
A388_RS15470	COG0473	3-isopropylmalate dehydrogenase activity
A388_RS15475	COG0583	DNA-binding transcription factor activity
A388_RS15495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
A388_RS15520	COG0564	pseudouridine synthase activity
A388_RS15530	COG0358	DNA primase activity
A388_RS15545	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
A388_RS15575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A388_RS15605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
A388_RS15615	COG0352	thiamine-phosphate diphosphorylase activity
A388_RS15615	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A388_RS15615	COG0351	phosphomethylpyrimidine kinase
A388_RS15620	COG1652	LysM domain
A388_RS15645	COG1399	metal-binding, possibly nucleic acid-binding protein
A388_RS15650	COG3101	peptidyl-lysine hydroxylation
A388_RS15655	COG0009	L-threonylcarbamoyladenylate synthase
A388_RS15660	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
A388_RS15665	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
A388_RS15680	COG4106	trans-aconitate 2-methyltransferase activity
A388_RS15695	COG2226	methyltransferase
A388_RS15695	COG0596	Alpha beta hydrolase
A388_RS15695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A388_RS15700	COG1877	trehalose-phosphatase activity
A388_RS15705	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
A388_RS15710	COG2223	nitrite transmembrane transporter activity
A388_RS15730	COG1196	nuclear chromosome segregation
A388_RS15740	COG0730	response to heat
A388_RS15755	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A388_RS15765	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A388_RS15825	COG0489	protein tyrosine kinase activity
A388_RS15835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A388_RS15835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A388_RS15865	COG2515	1-aminocyclopropane-1-carboxylate deaminase
A388_RS15870	COG2081	HI0933 family
A388_RS15880	COG0668	transmembrane transport
A388_RS15900	COG0583	DNA-binding transcription factor activity
A388_RS15925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A388_RS15930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A388_RS15960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A388_RS16000	COG0745	RESPONSE REGULATOR receiver
A388_RS16020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A388_RS16030	COG0384	phenazine biosynthesis protein PhzF
A388_RS16065	COG1309	transcriptional regulator
A388_RS16075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS16090	COG0583	DNA-binding transcription factor activity
A388_RS16120	COG0583	DNA-binding transcription factor activity
A388_RS16140	COG0583	DNA-binding transcription factor activity
A388_RS16145	COG1053	succinate dehydrogenase
A388_RS16155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
A388_RS16160	COG2814	Major facilitator Superfamily
A388_RS16165	COG1960	acyl-CoA dehydrogenase activity
A388_RS16170	COG0583	DNA-binding transcription factor activity
A388_RS16175	COG1063	alcohol dehydrogenase
A388_RS16210	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A388_RS16215	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
A388_RS16220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A388_RS16235	COG3667	copper resistance
A388_RS16240	COG2132	Multicopper oxidase
A388_RS16250	COG0561	phosphatase activity
A388_RS16255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
A388_RS16265	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
A388_RS16280	COG1214	PFAM Peptidase M22, glycoprotease
A388_RS16330	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
A388_RS16340	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
A388_RS16345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A388_RS16350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
A388_RS16410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A388_RS16420	COG1846	Transcriptional regulator
A388_RS16425	COG1764	response to oxidative stress
A388_RS16465	COG0037	tRNA processing
A388_RS16475	COG0248	Ppx GppA phosphatase
A388_RS16505	COG0072	phenylalanine-tRNA ligase activity
A388_RS16540	COG1238	metal cluster binding
A388_RS16545	COG0625	glutathione transferase activity
A388_RS16560	COG0318	PFAM AMP-dependent synthetase and ligase
A388_RS16565	COG3028	Belongs to the UPF0307 family
A388_RS16570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
A388_RS16590	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A388_RS16595	COG0617	tRNA 3'-terminal CCA addition
A388_RS16600	COG1555	photosystem II stabilization
A388_RS16605	COG3956	TIGRFAM MazG family protein
A388_RS16615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
A388_RS16635	COG5002	protein histidine kinase activity
A388_RS16635	COG0784	Response regulator, receiver
A388_RS16635	COG2205	protein histidine kinase activity
A388_RS16640	COG1024	Enoyl-CoA hydratase
A388_RS16645	COG2084	Dehydrogenase
A388_RS16650	COG3622	Belongs to the hyi family
A388_RS16680	COG0697	spore germination
A388_RS16690	COG2814	Major facilitator Superfamily
A388_RS16710	COG2132	Multicopper oxidase
A388_RS16725	COG2205	protein histidine kinase activity
A388_RS16815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
A388_RS16825	COG0583	DNA-binding transcription factor activity
A388_RS16835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
A388_RS16845	COG0084	hydrolase, TatD family'
A388_RS16860	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
A388_RS16895	COG0440	acetolactate synthase activity
A388_RS16900	COG0028	Belongs to the TPP enzyme family
A388_RS16925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS16930	COG1136	(ABC) transporter
A388_RS16930	COG0577	efflux transmembrane transporter activity
A388_RS16935	COG1538	Outer membrane efflux protein
A388_RS16950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
A388_RS16955	COG1162	GTPase activity
A388_RS16965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
A388_RS17005	COG1426	Protein conserved in bacteria
A388_RS17040	COG0793	Belongs to the peptidase S41A family
A388_RS17055	COG2267	carboxylic ester hydrolase activity
A388_RS17065	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS17070	COG3265	gluconokinase activity
A388_RS17080	COG0800	Aldolase
A388_RS17095	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
A388_RS17100	COG0280	phosphate acetyltransferase
A388_RS17100	COG0857	belongs to the CobB CobQ family
A388_RS17105	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
A388_RS17105	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
A388_RS17125	COG0740	serine-type endopeptidase activity
A388_RS17135	COG4774	siderophore transport
A388_RS17145	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
A388_RS17155	COG2813	Specifically methylates the guanine in position
A388_RS17155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
A388_RS17255	COG0788	formyltetrahydrofolate deformylase activity
A388_RS17280	COG4651	solute:proton antiporter activity
A388_RS17280	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A388_RS17300	COG0724	RNA recognition motif
A388_RS17305	COG0210	DNA helicase
A388_RS17330	COG1733	regulation of RNA biosynthetic process
A388_RS17340	COG2900	Belongs to the SlyX family
A388_RS17345	COG0488	(ABC) transporter
A388_RS17350	COG1280	lysine exporter protein (LysE YggA)
A388_RS17355	COG1560	Kdo2-lipid A biosynthetic process
A388_RS17365	COG1301	dicarboxylic acid transport
A388_RS17420	COG0473	3-isopropylmalate dehydrogenase activity
A388_RS17475	COG0583	DNA-binding transcription factor activity
A388_RS17485	COG0625	glutathione transferase activity
A388_RS17490	COG2378	regulation of single-species biofilm formation
A388_RS17495	COG0546	phosphoglycolate phosphatase activity
A388_RS17510	COG1530	ribonuclease E activity
A388_RS17515	COG0318	PFAM AMP-dependent synthetase and ligase
A388_RS17530	COG0583	DNA-binding transcription factor activity
A388_RS17535	COG4221	oxidoreductase activity
A388_RS17540	COG0635	Involved in the biosynthesis of porphyrin-containing compound
A388_RS17550	COG0534	Mate efflux family protein
A388_RS17565	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
A388_RS17590	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
A388_RS17590	COG0493	'glutamate synthase
A388_RS17600	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
A388_RS17605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A388_RS17620	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A388_RS17630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
A388_RS17630	COG0644	oxidoreductase
A388_RS17640	COG0425	Belongs to the sulfur carrier protein TusA family
A388_RS17645	COG4535	Mg2 and Co2 transporter CorC
A388_RS17655	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A388_RS17675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
A388_RS17680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
A388_RS17680	COG0475	glutathione-regulated potassium exporter activity
A388_RS17695	COG0484	heat shock protein binding
A388_RS17700	COG0789	Transcriptional regulator
A388_RS17705	COG0598	Magnesium transport protein CorA
A388_RS17720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
A388_RS17725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
A388_RS17730	COG1074	ATP-dependent DNA helicase activity
A388_RS17735	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
A388_RS17755	COG2226	methyltransferase
A388_RS17770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A388_RS17775	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A388_RS17790	COG2111	Na H antiporter
A388_RS17790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A388_RS17795	COG1006	Multisubunit Na H antiporter MnhC subunit
A388_RS17800	COG0651	ATP synthesis coupled electron transport
A388_RS17805	COG1863	multisubunit Na H antiporter MnhE subunit
A388_RS17810	COG2212	antiporter activity
A388_RS17815	COG1320	monovalent cation:proton antiporter activity
A388_RS17830	COG0195	Participates in both transcription termination and antitermination
A388_RS17880	COG0237	dephospho-CoA kinase activity
A388_RS17890	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
A388_RS17905	COG0497	DNA recombination
A388_RS17915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
A388_RS17950	COG2169	Transcriptional regulator
A388_RS17950	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
A388_RS17955	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
A388_RS18015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
A388_RS18030	COG0326	Molecular chaperone. Has ATPase activity
A388_RS18045	COG2056	Na+-H+ antiporter family
A388_RS18145	COG0546	phosphoglycolate phosphatase activity
A388_RS18150	COG1716	ATPase activity
A388_RS18195	COG0181	hydroxymethylbilane synthase activity
A388_RS18205	COG3275	phosphorelay sensor kinase activity
A388_RS18225	COG1538	Outer membrane efflux protein
A388_RS18230	COG0697	spore germination
A388_RS18255	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
A388_RS18260	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A388_RS18265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A388_RS18270	COG0772	Belongs to the SEDS family
A388_RS18295	COG4974	Belongs to the 'phage' integrase family
A388_RS18300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
A388_RS18310	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A388_RS18320	COG2197	response regulator
A388_RS18335	COG0793	Belongs to the peptidase S41A family
A388_RS18340	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
A388_RS18345	COG0795	lipopolysaccharide-transporting ATPase activity
A388_RS18385	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A388_RS18385	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
A388_RS18395	COG0004	ammonium transporteR
A388_RS18400	COG0347	Belongs to the P(II) protein family
A388_RS18410	COG0606	chelatase, subunit chli
A388_RS18420	COG0659	secondary active sulfate transmembrane transporter activity
A388_RS18450	COG0789	Transcriptional regulator
A388_RS18565	COG1335	isochorismatase
A388_RS18575	COG1012	belongs to the aldehyde dehydrogenase family
A388_RS18580	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A388_RS18590	COG1113	amino acid transport
A388_RS18600	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
A388_RS18615	COG2814	Major facilitator Superfamily
A388_RS18625	COG0351	phosphomethylpyrimidine kinase
A388_RS18625	COG0352	thiamine-phosphate diphosphorylase activity
A388_RS18625	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
A388_RS18645	COG1309	transcriptional regulator
A388_RS18650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
A388_RS18665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
A388_RS18675	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A388_RS18680	COG3162	membrane
A388_RS18685	COG2198	Histidine kinase
A388_RS18685	COG0784	Response regulator, receiver
A388_RS18685	COG2205	protein histidine kinase activity
A388_RS18710	COG1522	sequence-specific DNA binding
A388_RS18715	COG1335	isochorismatase
A388_RS18720	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A388_RS18730	COG0668	transmembrane transport
A388_RS18735	COG1385	rRNA (uridine-N3-)-methyltransferase activity
A388_RS18740	COG1519	Transferase
A388_RS18745	COG1902	pentaerythritol trinitrate reductase activity
A388_RS18765	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
A388_RS18790	COG0426	domain, Protein
A388_RS18790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A388_RS18795	COG4774	siderophore transport
A388_RS18800	COG2119	membrane
A388_RS18810	COG0508	dehydrogenase complex catalyzes the overall conversion of
A388_RS18820	COG4942	peptidase
A388_RS18835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A388_RS18845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
A388_RS18865	COG0189	ligase activity
A388_RS18885	COG0708	Exodeoxyribonuclease III
A388_RS18890	COG1393	Belongs to the ArsC family
A388_RS18905	COG3706	GGDEF domain
A388_RS18940	COG2351	hydroxyisourate hydrolase activity
A388_RS18945	COG2233	PERMEase
A388_RS18955	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A388_RS18965	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
A388_RS18975	COG3150	esterase
A388_RS19005	COG3409	Peptidoglycan-binding domain 1 protein
A388_RS19005	COG1388	LysM domain
A388_RS19005	COG5632	N-Acetylmuramoyl-L-alanine amidase
A388_RS19020	COG2918	glutathione biosynthetic process
A388_RS19035	COG2733	membrane
A388_RS19040	COG0436	Aminotransferase
A388_RS19045	COG0534	Mate efflux family protein
A388_RS19135	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A388_RS19140	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
A388_RS19150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A388_RS19180	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
A388_RS19195	COG0010	Belongs to the arginase family
A388_RS19225	COG2188	Transcriptional regulator
A388_RS19235	COG0523	cobalamin synthesis protein
A388_RS19245	COG1113	amino acid transport
A388_RS19255	COG0625	glutathione transferase activity
A388_RS19275	COG1683	Conserved Protein
A388_RS19280	COG0534	Mate efflux family protein
A388_RS19285	COG0385	Bile acid
A388_RS19290	COG1335	isochorismatase
A388_RS19295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A388_RS19315	COG2116	formate transmembrane transporter activity
A388_RS19320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A388_RS19325	COG2133	pyrroloquinoline quinone binding
A388_RS19330	COG2983	Belongs to the UPF0260 family
A388_RS19350	COG1194	a g-specific adenine glycosylase
A388_RS19365	COG2818	Glycosylase
A388_RS19370	COG1064	alcohol dehydrogenase
A388_RS19375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A388_RS19390	COG0583	DNA-binding transcription factor activity
A388_RS19395	COG0656	L-ascorbic acid biosynthetic process
A388_RS19400	COG2814	Major facilitator Superfamily
A388_RS19435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
A388_RS19450	COG2233	PERMEase
A388_RS19455	COG0583	DNA-binding transcription factor activity
A388_RS19480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A388_RS19490	COG0733	neurotransmitter:sodium symporter activity
A388_RS19500	COG0625	glutathione transferase activity
A388_RS19610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
A388_RS19620	COG2026	Addiction module toxin, RelE StbE family
A388_RS19645	COG1192	Involved in chromosome partitioning