locus-tag	class	description
NIY05_RS00010	COG0592	DNA-directed DNA polymerase activity
NIY05_RS00020	COG0187	DNA topoisomerase II activity
NIY05_RS00030	COG0586	Pfam SNARE associated Golgi protein
NIY05_RS00035	COG0488	(ABC) transporter
NIY05_RS00060	COG0596	Alpha beta hydrolase
NIY05_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NIY05_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIY05_RS00110	COG0733	neurotransmitter:sodium symporter activity
NIY05_RS00150	COG2233	PERMEase
NIY05_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS00200	COG2814	Major facilitator Superfamily
NIY05_RS00205	COG0656	L-ascorbic acid biosynthetic process
NIY05_RS00210	COG0583	DNA-binding transcription factor activity
NIY05_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY05_RS00230	COG1064	alcohol dehydrogenase
NIY05_RS00235	COG2818	Glycosylase
NIY05_RS00250	COG1194	a g-specific adenine glycosylase
NIY05_RS00270	COG2983	Belongs to the UPF0260 family
NIY05_RS00275	COG2133	pyrroloquinoline quinone binding
NIY05_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NIY05_RS00285	COG2116	formate transmembrane transporter activity
NIY05_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY05_RS00310	COG1335	isochorismatase
NIY05_RS00315	COG0385	Bile acid
NIY05_RS00320	COG0534	Mate efflux family protein
NIY05_RS00325	COG1683	Conserved Protein
NIY05_RS00345	COG0625	glutathione transferase activity
NIY05_RS00355	COG1113	amino acid transport
NIY05_RS00365	COG0523	cobalamin synthesis protein
NIY05_RS00375	COG2188	Transcriptional regulator
NIY05_RS00405	COG0010	Belongs to the arginase family
NIY05_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY05_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NIY05_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NIY05_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NIY05_RS00540	COG0534	Mate efflux family protein
NIY05_RS00545	COG0436	Aminotransferase
NIY05_RS00550	COG2733	membrane
NIY05_RS00565	COG2918	glutathione biosynthetic process
NIY05_RS00580	COG1388	LysM domain
NIY05_RS00580	COG0791	NLP P60 protein
NIY05_RS00595	COG3150	esterase
NIY05_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
NIY05_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY05_RS00630	COG2233	PERMEase
NIY05_RS00635	COG2351	hydroxyisourate hydrolase activity
NIY05_RS00670	COG3706	GGDEF domain
NIY05_RS00685	COG1393	Belongs to the ArsC family
NIY05_RS00690	COG0708	Exodeoxyribonuclease III
NIY05_RS00710	COG0189	ligase activity
NIY05_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NIY05_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIY05_RS00755	COG4942	peptidase
NIY05_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY05_RS00775	COG2119	membrane
NIY05_RS00780	COG4774	siderophore transport
NIY05_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY05_RS00785	COG0426	domain, Protein
NIY05_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NIY05_RS00830	COG1902	pentaerythritol trinitrate reductase activity
NIY05_RS00835	COG1519	Transferase
NIY05_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY05_RS00845	COG0668	transmembrane transport
NIY05_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY05_RS00860	COG1335	isochorismatase
NIY05_RS00865	COG1522	sequence-specific DNA binding
NIY05_RS00870	COG3328	transposase activity
NIY05_RS00900	COG0784	Response regulator, receiver
NIY05_RS00900	COG2198	Histidine kinase
NIY05_RS00900	COG2205	protein histidine kinase activity
NIY05_RS00905	COG3162	membrane
NIY05_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY05_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY05_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NIY05_RS00945	COG1309	transcriptional regulator
NIY05_RS00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY05_RS00965	COG0352	thiamine-phosphate diphosphorylase activity
NIY05_RS00965	COG0351	phosphomethylpyrimidine kinase
NIY05_RS00975	COG2814	Major facilitator Superfamily
NIY05_RS00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY05_RS01000	COG1113	amino acid transport
NIY05_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY05_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS01025	COG1335	isochorismatase
NIY05_RS01055	COG2814	Major facilitator Superfamily
NIY05_RS01060	COG0583	DNA-binding transcription factor activity
NIY05_RS01080	COG0667	Aldo Keto reductase
NIY05_RS01115	COG1733	regulation of RNA biosynthetic process
NIY05_RS01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY05_RS01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NIY05_RS01200	COG2329	Antibiotic biosynthesis monooxygenase
NIY05_RS01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIY05_RS01260	COG0427	acetyl-CoA hydrolase
NIY05_RS01285	COG0659	secondary active sulfate transmembrane transporter activity
NIY05_RS01290	COG4221	oxidoreductase activity
NIY05_RS01295	COG2873	o-acetylhomoserine
NIY05_RS01300	COG0488	(ABC) transporter
NIY05_RS01385	COG0833	amino acid
NIY05_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIY05_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NIY05_RS01450	COG2226	methyltransferase
NIY05_RS01500	COG0067	glutamate synthase
NIY05_RS01500	COG0069	glutamate synthase activity
NIY05_RS01500	COG0070	glutamate synthase
NIY05_RS01505	COG0493	'glutamate synthase
NIY05_RS01515	COG1704	LemA family
NIY05_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NIY05_RS01540	COG3307	-O-antigen
NIY05_RS01565	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY05_RS01580	COG0194	GDP metabolic process
NIY05_RS01630	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIY05_RS01650	COG5380	lipid catabolic process
NIY05_RS01655	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIY05_RS01680	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NIY05_RS01685	COG0277	FAD linked oxidase domain protein
NIY05_RS01695	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
NIY05_RS01700	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY05_RS01715	COG1289	transmembrane transporter activity
NIY05_RS01725	COG0628	permease
NIY05_RS01730	COG1192	Involved in chromosome partitioning
NIY05_RS01760	COG0833	amino acid
NIY05_RS01765	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY05_RS01770	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY05_RS01780	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS01820	COG0583	DNA-binding transcription factor activity
NIY05_RS01865	COG0517	IMP dehydrogenase activity
NIY05_RS01870	COG1983	PspC domain protein
NIY05_RS01880	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS01895	COG0408	coproporphyrinogen oxidase activity
NIY05_RS01915	COG0513	Belongs to the DEAD box helicase family
NIY05_RS01925	COG1127	ABC transporter
NIY05_RS01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NIY05_RS01940	COG2854	intermembrane phospholipid transfer
NIY05_RS01950	COG0598	Magnesium transport protein CorA
NIY05_RS01960	COG0494	nUDIX hydrolase
NIY05_RS01965	COG1040	competence protein
NIY05_RS01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIY05_RS01990	COG1946	Acyl-CoA thioesterase
NIY05_RS01995	COG1301	dicarboxylic acid transport
NIY05_RS02010	COG1959	2 iron, 2 sulfur cluster binding
NIY05_RS02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY05_RS02015	COG1017	nitric oxide dioxygenase activity
NIY05_RS02020	COG0433	COG0433 Predicted ATPase
NIY05_RS02025	COG0626	cystathionine gamma-synthase activity
NIY05_RS02180	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
NIY05_RS02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NIY05_RS02220	COG0339	signal peptide processing
NIY05_RS02225	COG0557	exoribonuclease II activity
NIY05_RS02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
NIY05_RS02275	COG2169	Transcriptional regulator
NIY05_RS02280	COG0697	spore germination
NIY05_RS02285	COG1295	ribonuclease BN
NIY05_RS02320	COG1702	phosphate starvation-inducible protein PhoH
NIY05_RS02330	COG1196	nuclear chromosome segregation
NIY05_RS02330	COG0741	lytic transglycosylase activity
NIY05_RS02330	COG0739	heme binding
NIY05_RS02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NIY05_RS02365	COG1183	phosphatidylcholine synthase activity
NIY05_RS02410	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS02415	COG1309	transcriptional regulator
NIY05_RS02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY05_RS02435	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS02455	COG2969	positive regulation of protein catabolic process
NIY05_RS02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NIY05_RS02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NIY05_RS02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NIY05_RS02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIY05_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY05_RS02520	COG1408	metallophosphoesterase
NIY05_RS02530	COG2199	diguanylate cyclase activity
NIY05_RS02590	COG1607	acyl-coa hydrolase
NIY05_RS02620	COG2350	Protein conserved in bacteria
NIY05_RS02630	COG0613	PHP domain protein
NIY05_RS02635	COG3781	membrane
NIY05_RS02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIY05_RS02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NIY05_RS02660	COG1862	Preprotein translocase
NIY05_RS02690	COG2205	protein histidine kinase activity
NIY05_RS02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NIY05_RS02715	COG0726	polysaccharide deacetylase
NIY05_RS02720	COG0463	Glycosyl transferase, family 2
NIY05_RS02725	COG0438	transferase activity, transferring glycosyl groups
NIY05_RS02790	COG0625	glutathione transferase activity
NIY05_RS02795	COG0583	DNA-binding transcription factor activity
NIY05_RS02800	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS02805	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS02815	COG2205	protein histidine kinase activity
NIY05_RS02820	COG0745	RESPONSE REGULATOR receiver
NIY05_RS02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NIY05_RS02845	COG2096	Adenosyltransferase
NIY05_RS02895	COG0285	dihydrofolate synthase activity
NIY05_RS02915	COG0450	alkyl hydroperoxide reductase
NIY05_RS02930	COG0477	Major facilitator Superfamily
NIY05_RS02935	COG1272	protein, Hemolysin III
NIY05_RS02965	COG0183	Belongs to the thiolase family
NIY05_RS02970	COG2207	Transcriptional regulator
NIY05_RS02990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY05_RS03010	COG0183	Belongs to the thiolase family
NIY05_RS03020	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
NIY05_RS03020	COG2885	chlorophyll binding
NIY05_RS03030	COG1690	Belongs to the RtcB family
NIY05_RS03035	COG0833	amino acid
NIY05_RS03045	COG2233	PERMEase
NIY05_RS03050	COG1217	gtp-binding protein TYPA
NIY05_RS03075	COG2094	Belongs to the DNA glycosylase MPG family
NIY05_RS03095	COG1902	pentaerythritol trinitrate reductase activity
NIY05_RS03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY05_RS03115	COG0354	folic acid binding
NIY05_RS03125	COG3189	MarR family transcriptional regulator
NIY05_RS03130	COG2824	Alkylphosphonate utilization operon protein PhnA
NIY05_RS03135	COG3422	double-strand break repair
NIY05_RS03175	COG0840	transmembrane signaling receptor activity
NIY05_RS03195	COG5510	response to toxic substance
NIY05_RS03205	COG2832	Protein of unknown function (DUF454)
NIY05_RS03210	COG1376	ErfK ybiS ycfS ynhG family protein
NIY05_RS03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NIY05_RS03260	COG1289	transmembrane transporter activity
NIY05_RS03265	COG2814	Major facilitator Superfamily
NIY05_RS03285	COG1115	amino acid carrier protein
NIY05_RS03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY05_RS03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY05_RS03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
NIY05_RS03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY05_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIY05_RS03345	COG1077	Cell shape determining protein MreB Mrl
NIY05_RS03350	COG1792	Involved in formation and maintenance of cell shape
NIY05_RS03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NIY05_RS03360	COG0424	maF-like protein
NIY05_RS03365	COG1530	ribonuclease E activity
NIY05_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY05_RS03385	COG0560	Phosphoserine phosphatase
NIY05_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY05_RS03420	COG2207	Transcriptional regulator
NIY05_RS03440	COG1113	amino acid transport
NIY05_RS03445	COG2828	Protein conserved in bacteria
NIY05_RS03450	COG0142	geranyltranstransferase activity
NIY05_RS03455	COG2315	Protein conserved in bacteria
NIY05_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
NIY05_RS03490	COG2194	sulfuric ester hydrolase activity
NIY05_RS03495	COG0745	RESPONSE REGULATOR receiver
NIY05_RS03500	COG0642	Histidine kinase
NIY05_RS03510	COG0004	ammonium transporteR
NIY05_RS03515	COG0583	DNA-binding transcription factor activity
NIY05_RS03535	COG0525	valine-tRNA ligase activity
NIY05_RS03545	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS03555	COG0393	Putative heavy-metal-binding
NIY05_RS03560	COG0393	Putative heavy-metal-binding
NIY05_RS03565	COG1538	Outer membrane efflux protein
NIY05_RS03575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS03580	COG0671	phosphoesterase, PA-phosphatase related
NIY05_RS03610	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NIY05_RS03625	COG1648	precorrin-2 dehydrogenase activity
NIY05_RS03625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NIY05_RS03630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NIY05_RS03635	COG1733	regulation of RNA biosynthetic process
NIY05_RS03645	COG0531	amino acid
NIY05_RS03660	COG0321	lipoyl(octanoyl) transferase activity
NIY05_RS03665	COG2921	Belongs to the UPF0250 family
NIY05_RS03705	COG2009	succinate dehydrogenase
NIY05_RS03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NIY05_RS03715	COG1053	succinate dehydrogenase
NIY05_RS03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NIY05_RS03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY05_RS03765	COG2354	Protein conserved in bacteria
NIY05_RS03770	COG2321	neutral zinc metallopeptidase
NIY05_RS03790	COG2843	Capsule synthesis protein
NIY05_RS03805	COG0589	response to stress
NIY05_RS03825	COG0505	Belongs to the CarA family
NIY05_RS03850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY05_RS03855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NIY05_RS03905	COG0477	Major facilitator Superfamily
NIY05_RS03910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIY05_RS03925	COG1597	lipid kinase activity
NIY05_RS03930	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY05_RS03960	COG0584	glycerophosphoryl diester phosphodiesterase
NIY05_RS03980	COG0741	lytic transglycosylase activity
NIY05_RS04000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NIY05_RS04015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY05_RS04045	COG0778	Nitroreductase
NIY05_RS04060	COG1929	Belongs to the glycerate kinase type-1 family
NIY05_RS04065	COG0243	molybdopterin cofactor binding
NIY05_RS04070	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NIY05_RS04075	COG3339	Conserved Protein
NIY05_RS04085	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
NIY05_RS04100	COG1113	amino acid transport
NIY05_RS04110	COG0019	diaminopimelate decarboxylase activity
NIY05_RS04120	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS04125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NIY05_RS04155	COG0463	Glycosyl transferase, family 2
NIY05_RS04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS04210	COG4591	ABC-type transport system involved in lipoprotein release permease component
NIY05_RS04215	COG1136	(ABC) transporter
NIY05_RS04220	COG0658	competence protein
NIY05_RS04220	COG2333	competence protein COMEC
NIY05_RS04230	COG0616	signal peptide processing
NIY05_RS04230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NIY05_RS04235	COG0596	Alpha beta hydrolase
NIY05_RS04240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIY05_RS04250	COG0628	permease
NIY05_RS04285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY05_RS04305	COG0823	Involved in the tonB-independent uptake of proteins
NIY05_RS04325	COG0824	Thioesterase
NIY05_RS04330	COG1473	amidohydrolase
NIY05_RS04350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIY05_RS04350	COG0047	phosphoribosylformylglycinamidine synthase activity
NIY05_RS04355	COG2814	Major facilitator Superfamily
NIY05_RS04370	COG1024	Enoyl-CoA hydratase
NIY05_RS04375	COG1051	belongs to the nudix hydrolase family
NIY05_RS04375	COG1056	cytidyltransferase-related domain
NIY05_RS04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NIY05_RS04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NIY05_RS04415	COG4625	pathogenesis
NIY05_RS04420	COG0583	DNA-binding transcription factor activity
NIY05_RS04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NIY05_RS04430	COG4208	sulfate ABC transporter
NIY05_RS04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NIY05_RS04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NIY05_RS04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NIY05_RS04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIY05_RS04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY05_RS04490	COG0681	Belongs to the peptidase S26 family
NIY05_RS04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIY05_RS04515	COG1381	Involved in DNA repair and RecF pathway recombination
NIY05_RS04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NIY05_RS04530	COG4221	oxidoreductase activity
NIY05_RS04560	COG0436	Aminotransferase
NIY05_RS04580	COG0556	nucleotide-excision repair
NIY05_RS04635	COG2070	2-Nitropropane dioxygenase
NIY05_RS04665	COG1215	transferase activity, transferring glycosyl groups
NIY05_RS04680	COG0415	Belongs to the DNA photolyase family
NIY05_RS04690	COG1252	NADH dehydrogenase
NIY05_RS04695	COG1686	Belongs to the peptidase S11 family
NIY05_RS04710	COG1187	pseudouridine synthase activity
NIY05_RS04735	COG0477	Major facilitator Superfamily
NIY05_RS04740	COG0583	DNA-binding transcription factor activity
NIY05_RS04745	COG1823	symporter activity
NIY05_RS04755	COG0612	Peptidase, M16
NIY05_RS04780	COG0352	thiamine-phosphate diphosphorylase activity
NIY05_RS04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY05_RS04830	COG1309	transcriptional regulator
NIY05_RS04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIY05_RS04845	COG0076	glutamate decarboxylase activity
NIY05_RS04855	COG1522	sequence-specific DNA binding
NIY05_RS04860	COG3961	Belongs to the TPP enzyme family
NIY05_RS04865	COG1113	amino acid transport
NIY05_RS04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY05_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
NIY05_RS04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NIY05_RS04890	COG0616	signal peptide processing
NIY05_RS04925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NIY05_RS04930	COG1686	Belongs to the peptidase S11 family
NIY05_RS04955	COG0583	DNA-binding transcription factor activity
NIY05_RS04960	COG1067	ATP-dependent peptidase activity
NIY05_RS05005	COG1966	Carbon starvation protein
NIY05_RS05010	COG2879	small protein
NIY05_RS05045	COG2508	Transcriptional regulator
NIY05_RS05045	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NIY05_RS05065	COG1113	amino acid transport
NIY05_RS05070	COG0583	DNA-binding transcription factor activity
NIY05_RS05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY05_RS05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY05_RS05090	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS05100	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY05_RS05105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY05_RS05105	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NIY05_RS05140	COG2814	Major facilitator Superfamily
NIY05_RS05145	COG4948	Mandelate Racemase Muconate Lactonizing
NIY05_RS05155	COG1309	transcriptional regulator
NIY05_RS05175	COG1741	Belongs to the pirin family
NIY05_RS05185	COG2964	Protein conserved in bacteria
NIY05_RS05200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY05_RS05205	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY05_RS05210	COG4605	iron ion homeostasis
NIY05_RS05215	COG4604	ABC transporter, ATP-binding protein
NIY05_RS05220	COG4607	ABC-type enterochelin transport system periplasmic component
NIY05_RS05225	COG4774	siderophore transport
NIY05_RS05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NIY05_RS05240	COG1021	2,3-dihydroxybenzoate-AMP ligase
NIY05_RS05245	COG3433	isochorismatase activity
NIY05_RS05245	COG1535	isochorismatase
NIY05_RS05260	COG1132	(ABC) transporter
NIY05_RS05265	COG1132	(ABC) transporter
NIY05_RS05270	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
NIY05_RS05280	COG1169	isochorismate synthase
NIY05_RS05295	COG3739	integral membrane protein
NIY05_RS05320	COG0302	gtp cyclohydrolase
NIY05_RS05330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NIY05_RS05360	COG0308	aminopeptidase N
NIY05_RS05365	COG0512	Glutamine amidotransferase of anthranilate synthase
NIY05_RS05380	COG0174	glutamine synthetase
NIY05_RS05390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NIY05_RS05425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NIY05_RS05430	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIY05_RS05435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NIY05_RS05455	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NIY05_RS05460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NIY05_RS05465	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
NIY05_RS05480	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS05485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY05_RS05490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY05_RS05500	COG2223	nitrite transmembrane transporter activity
NIY05_RS05510	COG0024	Methionine aminopeptidase
NIY05_RS05515	COG0052	Belongs to the universal ribosomal protein uS2 family
NIY05_RS05530	COG2207	Transcriptional regulator
NIY05_RS05555	COG2951	lytic endotransglycosylase activity
NIY05_RS05560	COG0772	Belongs to the SEDS family
NIY05_RS05575	COG0842	Transport permease protein
NIY05_RS05580	COG1131	(ABC) transporter
NIY05_RS05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS05640	COG4215	(ABC) transporter
NIY05_RS05645	COG4160	amino acid transport
NIY05_RS05650	COG4598	ABC transporter
NIY05_RS05660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY05_RS05665	COG0826	peptidase U32
NIY05_RS05670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY05_RS05685	COG1720	tRNA m6t6A37 methyltransferase activity
NIY05_RS05695	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NIY05_RS05710	COG0642	Histidine kinase
NIY05_RS05720	COG0494	nUDIX hydrolase
NIY05_RS05730	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NIY05_RS05735	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIY05_RS05740	COG3139	Protein of unknown function (DUF1315)
NIY05_RS05745	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIY05_RS05750	COG1301	dicarboxylic acid transport
NIY05_RS05755	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS05760	COG2819	hydrolase of the alpha beta superfamily
NIY05_RS05770	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NIY05_RS05780	COG2195	Cleaves the N-terminal amino acid of tripeptides
NIY05_RS05785	COG1234	tRNA 3'-trailer cleavage
NIY05_RS05815	COG2363	Small membrane protein
NIY05_RS05840	COG0513	Belongs to the DEAD box helicase family
NIY05_RS05850	COG0778	Nitroreductase
NIY05_RS06200	COG1286	toxin biosynthetic process
NIY05_RS06225	COG4783	chaperone-mediated protein folding
NIY05_RS06230	COG1610	YqeY-like protein
NIY05_RS06330	COG3111	PFAM Bacterial OB fold (BOF) protein
NIY05_RS06355	COG3243	poly(R)-hydroxyalkanoic acid synthase
NIY05_RS06360	COG0786	glutamate:sodium symporter activity
NIY05_RS06370	COG2186	Transcriptional regulator
NIY05_RS06420	COG0477	Major facilitator Superfamily
NIY05_RS06450	COG2985	domain, Protein
NIY05_RS06460	COG2995	paraquat-inducible protein a
NIY05_RS06465	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NIY05_RS06465	COG3008	intermembrane lipid transfer
NIY05_RS06475	COG1794	racemase activity, acting on amino acids and derivatives
NIY05_RS06570	COG0488	(ABC) transporter
NIY05_RS06575	COG3173	Aminoglycoside phosphotransferase
NIY05_RS06585	COG2433	Pfam Transposase IS66
NIY05_RS06605	COG1309	transcriptional regulator
NIY05_RS06610	COG1741	Belongs to the pirin family
NIY05_RS06625	COG2072	flavoprotein involved in K transport
NIY05_RS06635	COG2252	PERMEase
NIY05_RS06640	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NIY05_RS06645	COG3038	cytochrome b561
NIY05_RS06655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIY05_RS06665	COG0527	aspartate kinase activity
NIY05_RS06675	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NIY05_RS06685	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIY05_RS06700	COG0667	Aldo Keto reductase
NIY05_RS06720	COG1765	OsmC-like protein
NIY05_RS06735	COG0542	response to heat
NIY05_RS06770	COG2885	chlorophyll binding
NIY05_RS06780	COG0625	glutathione transferase activity
NIY05_RS06785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NIY05_RS06805	COG3634	alkyl hydroperoxide reductase activity
NIY05_RS06815	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NIY05_RS06825	COG0450	alkyl hydroperoxide reductase
NIY05_RS06830	COG1643	Atp-dependent helicase
NIY05_RS06845	COG2814	Major facilitator Superfamily
NIY05_RS06850	COG3135	benzoate transporter
NIY05_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS06860	COG0543	2 iron, 2 sulfur cluster binding
NIY05_RS06860	COG0633	Ferredoxin
NIY05_RS06865	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY05_RS06870	COG4638	Rieske (2fe-2S)
NIY05_RS06880	COG0583	DNA-binding transcription factor activity
NIY05_RS06930	COG1570	exodeoxyribonuclease VII activity
NIY05_RS06960	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS06965	COG1278	Cold shock
NIY05_RS07000	COG2814	Major facilitator Superfamily
NIY05_RS07035	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NIY05_RS07035	COG0517	IMP dehydrogenase activity
NIY05_RS07040	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NIY05_RS07050	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NIY05_RS07055	COG1137	ATPase activity
NIY05_RS07060	COG1538	Outer membrane efflux protein
NIY05_RS07090	COG4122	O-methyltransferase activity
NIY05_RS07100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NIY05_RS07115	COG1522	sequence-specific DNA binding
NIY05_RS07120	COG5006	permease, DMT superfamily
NIY05_RS07130	COG1560	Kdo2-lipid A biosynthetic process
NIY05_RS07145	COG2814	Major facilitator Superfamily
NIY05_RS07165	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY05_RS07215	COG0583	DNA-binding transcription factor activity
NIY05_RS07220	COG1914	H( )-stimulated, divalent metal cation uptake system
NIY05_RS07240	COG4770	biotin carboxylase activity
NIY05_RS07245	COG0038	chloride channel
NIY05_RS07265	COG1309	transcriptional regulator
NIY05_RS07275	COG1063	alcohol dehydrogenase
NIY05_RS07290	COG0439	Biotin carboxylase
NIY05_RS07295	COG2249	NAD(P)H dehydrogenase (quinone) activity
NIY05_RS07315	COG0864	Transcriptional regulator
NIY05_RS07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY05_RS07330	COG1116	anion transmembrane transporter activity
NIY05_RS07450	COG0590	tRNA wobble adenosine to inosine editing
NIY05_RS07455	COG2807	transmembrane transport
NIY05_RS07470	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NIY05_RS07485	COG0789	Transcriptional regulator
NIY05_RS07495	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY05_RS07515	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY05_RS07525	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY05_RS07540	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS07545	COG0531	amino acid
NIY05_RS07550	COG1760	l-serine dehydratase
NIY05_RS07555	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS07555	COG2030	dehydratase
NIY05_RS07560	COG3396	Phenylacetate-CoA oxygenase
NIY05_RS07565	COG3460	Phenylacetate-CoA oxygenase
NIY05_RS07570	COG3396	Phenylacetate-CoA oxygenase
NIY05_RS07575	COG2151	metal-sulfur cluster biosynthetic enzyme
NIY05_RS07580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY05_RS07585	COG1024	Enoyl-CoA hydratase
NIY05_RS07590	COG1024	Enoyl-CoA hydratase
NIY05_RS07595	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY05_RS07600	COG0183	Belongs to the thiolase family
NIY05_RS07605	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NIY05_RS07610	COG3327	negative regulation of DNA-templated transcription, initiation
NIY05_RS07620	COG2050	protein possibly involved in aromatic compounds catabolism
NIY05_RS07655	COG0753	catalase activity
NIY05_RS07660	COG3038	cytochrome b561
NIY05_RS07680	COG2267	carboxylic ester hydrolase activity
NIY05_RS07685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY05_RS07690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY05_RS07695	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS07705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY05_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS07720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY05_RS07725	COG0583	DNA-binding transcription factor activity
NIY05_RS07735	COG1414	Transcriptional regulator
NIY05_RS07740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY05_RS07750	COG1840	ABC-type Fe3 transport system, periplasmic component
NIY05_RS07755	COG3842	ATPase activity
NIY05_RS07770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
NIY05_RS07775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY05_RS07780	COG2814	Major facilitator Superfamily
NIY05_RS07785	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS07800	COG1024	Enoyl-CoA hydratase
NIY05_RS07810	COG2814	Major facilitator Superfamily
NIY05_RS07820	COG0183	Belongs to the thiolase family
NIY05_RS07825	COG1250	3-hydroxyacyl-CoA dehydrogenase
NIY05_RS07830	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS07835	COG1024	Enoyl-CoA hydratase
NIY05_RS07840	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS07845	COG2814	Major facilitator Superfamily
NIY05_RS07850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY05_RS07855	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY05_RS07865	COG2814	Major facilitator Superfamily
NIY05_RS07875	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS07890	COG0583	DNA-binding transcription factor activity
NIY05_RS07900	COG4770	biotin carboxylase activity
NIY05_RS07905	COG1024	Enoyl-CoA hydratase
NIY05_RS07910	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NIY05_RS07915	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS07920	COG1309	transcriptional regulator
NIY05_RS07925	COG0318	PFAM AMP-dependent synthetase and ligase
NIY05_RS07950	COG0583	DNA-binding transcription factor activity
NIY05_RS08000	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS08020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY05_RS08040	COG0784	Response regulator, receiver
NIY05_RS08040	COG2205	protein histidine kinase activity
NIY05_RS08060	COG0765	amino acid transport
NIY05_RS08065	COG0765	amino acid transport
NIY05_RS08070	COG1126	abc transporter atp-binding protein
NIY05_RS08075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY05_RS08080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NIY05_RS08095	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS08105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIY05_RS08110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY05_RS08115	COG1045	serine acetyltransferase
NIY05_RS08130	COG0583	DNA-binding transcription factor activity
NIY05_RS08135	COG0625	glutathione transferase activity
NIY05_RS08140	COG0625	glutathione transferase activity
NIY05_RS08145	COG0583	DNA-binding transcription factor activity
NIY05_RS08155	COG1346	cytolysis
NIY05_RS08175	COG2814	Major facilitator Superfamily
NIY05_RS08185	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
NIY05_RS08190	COG3052	prosthetic group binding
NIY05_RS08210	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NIY05_RS08230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY05_RS08240	COG1294	oxidase, subunit
NIY05_RS08245	COG1271	oxidase subunit
NIY05_RS08265	COG0477	Major facilitator Superfamily
NIY05_RS08275	COG4521	taurine ABC transporter
NIY05_RS08280	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
NIY05_RS08285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY05_RS08290	COG2175	clavaminate synthase activity
NIY05_RS08300	COG1953	Uracil, thiamine, allantoin
NIY05_RS08310	COG0583	DNA-binding transcription factor activity
NIY05_RS08320	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIY05_RS08335	COG0640	Transcriptional regulator
NIY05_RS08340	COG0798	PFAM Bile acid sodium symporter
NIY05_RS08345	COG0583	DNA-binding transcription factor activity
NIY05_RS08360	COG3634	alkyl hydroperoxide reductase activity
NIY05_RS08400	COG0436	Aminotransferase
NIY05_RS08410	COG0386	Belongs to the glutathione peroxidase family
NIY05_RS08450	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NIY05_RS08475	COG0012	GTP binding
NIY05_RS08480	COG2011	ABC-type metal ion transport system permease component
NIY05_RS08485	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY05_RS08495	COG1464	Belongs to the NlpA lipoprotein family
NIY05_RS08525	COG0765	amino acid transport
NIY05_RS08530	COG0765	amino acid transport
NIY05_RS08535	COG1126	abc transporter atp-binding protein
NIY05_RS08550	COG1522	sequence-specific DNA binding
NIY05_RS08565	COG1309	transcriptional regulator
NIY05_RS08585	COG0583	DNA-binding transcription factor activity
NIY05_RS08595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NIY05_RS08605	COG0697	spore germination
NIY05_RS08630	COG3121	Chaperone
NIY05_RS08635	COG3539	Fimbrial protein
NIY05_RS08660	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIY05_RS08660	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NIY05_RS08705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIY05_RS08715	COG2353	YceI-like domain
NIY05_RS08725	COG3698	Phosphodiester glycosidase
NIY05_RS08740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIY05_RS08745	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY05_RS08745	COG0506	proline dehydrogenase activity
NIY05_RS08745	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NIY05_RS08755	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NIY05_RS08760	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NIY05_RS08780	COG1132	(ABC) transporter
NIY05_RS08785	COG3122	Protein conserved in bacteria
NIY05_RS08790	COG3619	membrane
NIY05_RS08800	COG0640	Transcriptional regulator
NIY05_RS08820	COG2850	peptidyl-arginine hydroxylation
NIY05_RS08825	COG0424	maF-like protein
NIY05_RS08845	COG0191	fructose-bisphosphate aldolase activity
NIY05_RS08850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY05_RS08865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NIY05_RS08875	COG1192	Involved in chromosome partitioning
NIY05_RS08880	COG1475	DNA binding
NIY05_RS08885	COG0811	peptide transport
NIY05_RS08895	COG1132	(ABC) transporter
NIY05_RS08900	COG1663	tetraacyldisaccharide 4'-kinase activity
NIY05_RS08920	COG0084	hydrolase, TatD family'
NIY05_RS08985	COG0776	regulation of translation
NIY05_RS09015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NIY05_RS09020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NIY05_RS09070	COG0339	signal peptide processing
NIY05_RS09080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIY05_RS09115	COG0702	epimerase
NIY05_RS09120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY05_RS09150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIY05_RS09180	COG0316	Belongs to the HesB IscA family
NIY05_RS09185	COG0822	iron-sulfur transferase activity
NIY05_RS09210	COG0776	regulation of translation
NIY05_RS09215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NIY05_RS09220	COG2207	Transcriptional regulator
NIY05_RS09225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY05_RS09230	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS09235	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS09250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIY05_RS09270	COG4264	IucA IucC family
NIY05_RS09275	COG4264	IucA IucC family
NIY05_RS09315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NIY05_RS09330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NIY05_RS09350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NIY05_RS09355	COG0730	response to heat
NIY05_RS09375	COG4773	Receptor
NIY05_RS09380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY05_RS09395	COG1131	(ABC) transporter
NIY05_RS09400	COG0842	Transport permease protein
NIY05_RS09405	COG0842	Transport permease protein
NIY05_RS09460	COG2226	methyltransferase
NIY05_RS09485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIY05_RS09520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIY05_RS09530	COG0133	tryptophan synthase activity
NIY05_RS09545	COG3706	GGDEF domain
NIY05_RS09560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NIY05_RS09565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
NIY05_RS09570	COG0022	dehydrogenase e1 component
NIY05_RS09575	COG0508	dehydrogenase complex catalyzes the overall conversion of
NIY05_RS09580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NIY05_RS09590	COG1063	alcohol dehydrogenase
NIY05_RS09595	COG3781	membrane
NIY05_RS09605	COG3453	Protein conserved in bacteria
NIY05_RS09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY05_RS09620	COG0730	response to heat
NIY05_RS09635	COG2207	Transcriptional regulator
NIY05_RS09635	COG3708	Transcriptional regulator
NIY05_RS09640	COG1733	regulation of RNA biosynthetic process
NIY05_RS09645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIY05_RS09655	COG2188	Transcriptional regulator
NIY05_RS09670	COG4521	taurine ABC transporter
NIY05_RS09675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY05_RS09695	COG0477	Major facilitator Superfamily
NIY05_RS09705	COG1027	Aspartate ammonia-lyase
NIY05_RS09720	COG0583	DNA-binding transcription factor activity
NIY05_RS09725	COG0583	DNA-binding transcription factor activity
NIY05_RS09730	COG0183	Belongs to the thiolase family
NIY05_RS09735	COG2031	fatty acid transporter
NIY05_RS09740	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY05_RS09750	COG0583	DNA-binding transcription factor activity
NIY05_RS09760	COG2610	gluconate transmembrane transporter activity
NIY05_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS09775	COG2207	Transcriptional regulator
NIY05_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS09815	COG0543	2 iron, 2 sulfur cluster binding
NIY05_RS09815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NIY05_RS09820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
NIY05_RS09825	COG4638	Rieske (2fe-2S)
NIY05_RS09835	COG0725	ABC transporter, periplasmic molybdate-binding protein
NIY05_RS09840	COG4149	molybdate abc transporter
NIY05_RS09845	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NIY05_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS09855	COG3433	isochorismatase activity
NIY05_RS09855	COG1535	isochorismatase
NIY05_RS09920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIY05_RS09935	COG0753	catalase activity
NIY05_RS09945	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
NIY05_RS09975	COG3539	Fimbrial protein
NIY05_RS09995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NIY05_RS10015	COG2072	flavoprotein involved in K transport
NIY05_RS10025	COG1538	Outer membrane efflux protein
NIY05_RS10030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NIY05_RS10035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS10040	COG0745	RESPONSE REGULATOR receiver
NIY05_RS10070	COG2207	Transcriptional regulator
NIY05_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS10135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NIY05_RS10255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY05_RS10275	COG1120	ATPase activity
NIY05_RS10280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIY05_RS10290	COG1064	alcohol dehydrogenase
NIY05_RS10305	COG2207	Transcriptional regulator
NIY05_RS10310	COG2084	Dehydrogenase
NIY05_RS10320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NIY05_RS10325	COG0583	DNA-binding transcription factor activity
NIY05_RS10335	COG0129	dihydroxy-acid dehydratase activity
NIY05_RS10340	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS10355	COG1566	PFAM secretion protein HlyD family protein
NIY05_RS10390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NIY05_RS10420	COG0583	DNA-binding transcription factor activity
NIY05_RS10435	COG2188	Transcriptional regulator
NIY05_RS10465	COG3210	domain, Protein
NIY05_RS10470	COG2831	hemolysin activation secretion protein
NIY05_RS10480	COG1473	amidohydrolase
NIY05_RS10490	COG0475	glutathione-regulated potassium exporter activity
NIY05_RS10490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY05_RS10500	COG0583	DNA-binding transcription factor activity
NIY05_RS10505	COG1335	isochorismatase
NIY05_RS10515	COG1309	transcriptional regulator
NIY05_RS10545	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIY05_RS10555	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY05_RS10555	COG1902	pentaerythritol trinitrate reductase activity
NIY05_RS10560	COG1846	Transcriptional regulator
NIY05_RS10580	COG0753	catalase activity
NIY05_RS10595	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS10610	COG3162	membrane
NIY05_RS10620	COG3829	transcription factor binding
NIY05_RS10625	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS10630	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS10650	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS10670	COG2186	Transcriptional regulator
NIY05_RS10680	COG0583	DNA-binding transcription factor activity
NIY05_RS10685	COG4948	Mandelate Racemase Muconate Lactonizing
NIY05_RS10690	COG4829	muconolactone delta-isomerase
NIY05_RS10700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY05_RS10705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY05_RS10710	COG0183	Belongs to the thiolase family
NIY05_RS10715	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY05_RS10725	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS10735	COG3733	amine oxidase
NIY05_RS10745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY05_RS10755	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS10765	COG4638	Rieske (2fe-2S)
NIY05_RS10785	COG0154	amidase activity
NIY05_RS10795	COG2814	Major facilitator Superfamily
NIY05_RS10820	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS10825	COG0583	DNA-binding transcription factor activity
NIY05_RS10830	COG1414	Transcriptional regulator
NIY05_RS10845	COG2391	methyltransferase activity
NIY05_RS10855	COG4993	Dehydrogenase
NIY05_RS10860	COG3659	wide pore channel activity
NIY05_RS10865	COG3420	alginic acid biosynthetic process
NIY05_RS10870	COG0710	3-dehydroquinate dehydratase activity
NIY05_RS10875	COG3485	protocatechuate 3,4-dioxygenase
NIY05_RS10880	COG3485	protocatechuate 3,4-dioxygenase
NIY05_RS10885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NIY05_RS10890	COG2271	Major facilitator Superfamily
NIY05_RS10895	COG0596	Alpha beta hydrolase
NIY05_RS10900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIY05_RS10905	COG0183	Belongs to the thiolase family
NIY05_RS10910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
NIY05_RS10915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NIY05_RS10925	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NIY05_RS10930	COG2323	membrane
NIY05_RS10975	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY05_RS10975	COG1902	pentaerythritol trinitrate reductase activity
NIY05_RS11000	COG0542	response to heat
NIY05_RS11005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NIY05_RS11035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NIY05_RS11040	COG0569	domain protein
NIY05_RS11045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NIY05_RS11060	COG4774	siderophore transport
NIY05_RS11065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIY05_RS11075	COG1585	Membrane protein implicated in regulation of membrane protease activity
NIY05_RS11090	COG1294	oxidase, subunit
NIY05_RS11095	COG4890	Cyd operon protein YbgT
NIY05_RS11110	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
NIY05_RS11120	COG0552	protein localization to endoplasmic reticulum
NIY05_RS11145	COG0516	GMP reductase activity
NIY05_RS11145	COG0517	IMP dehydrogenase activity
NIY05_RS11150	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NIY05_RS11155	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NIY05_RS11165	COG0583	DNA-binding transcription factor activity
NIY05_RS11170	COG0024	Methionine aminopeptidase
NIY05_RS11200	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIY05_RS11200	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY05_RS11205	COG1105	Belongs to the carbohydrate kinase PfkB family
NIY05_RS11210	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY05_RS11210	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NIY05_RS11210	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NIY05_RS11230	COG3300	MHYT domain
NIY05_RS11230	COG5001	Diguanylate cyclase
NIY05_RS11245	COG2135	peptidase activity
NIY05_RS11250	COG0659	secondary active sulfate transmembrane transporter activity
NIY05_RS11270	COG1113	amino acid transport
NIY05_RS11280	COG1522	sequence-specific DNA binding
NIY05_RS11305	COG1011	Hydrolase
NIY05_RS11310	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NIY05_RS11320	COG2137	regulation of response to DNA damage stimulus
NIY05_RS11335	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY05_RS11370	COG0575	Belongs to the CDS family
NIY05_RS11375	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIY05_RS11395	COG3852	Histidine kinase
NIY05_RS11400	COG2204	response regulator
NIY05_RS11465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY05_RS11470	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NIY05_RS11490	COG0697	spore germination
NIY05_RS11495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY05_RS11505	COG0303	'Molybdopterin
NIY05_RS11510	COG0521	Mo-molybdopterin cofactor biosynthetic process
NIY05_RS11510	COG0315	cyclic pyranopterin monophosphate synthase activity
NIY05_RS11525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NIY05_RS11530	COG0243	molybdopterin cofactor binding
NIY05_RS11540	COG0243	molybdopterin cofactor binding
NIY05_RS11545	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY05_RS11550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY05_RS11550	COG2146	nitrite reductase [NAD(P)H] activity
NIY05_RS11560	COG0745	RESPONSE REGULATOR receiver
NIY05_RS11565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY05_RS11565	COG1116	anion transmembrane transporter activity
NIY05_RS11585	COG0511	ligase activity, forming carbon-carbon bonds
NIY05_RS11600	COG2814	Major facilitator Superfamily
NIY05_RS11670	COG1196	nuclear chromosome segregation
NIY05_RS11670	COG0739	heme binding
NIY05_RS11670	COG0741	lytic transglycosylase activity
NIY05_RS11810	COG5410	chromosome segregation
NIY05_RS11985	COG0069	glutamate synthase activity
NIY05_RS12005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIY05_RS12015	COG1454	alcohol dehydrogenase
NIY05_RS12020	COG0824	Thioesterase
NIY05_RS12030	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIY05_RS12045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY05_RS12050	COG2030	dehydratase
NIY05_RS12060	COG0183	Belongs to the thiolase family
NIY05_RS12070	COG0583	DNA-binding transcription factor activity
NIY05_RS12075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIY05_RS12085	COG1522	sequence-specific DNA binding
NIY05_RS12090	COG3135	benzoate transporter
NIY05_RS12100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NIY05_RS12125	COG0589	response to stress
NIY05_RS12130	COG0488	(ABC) transporter
NIY05_RS12150	COG4773	Receptor
NIY05_RS12185	COG0668	transmembrane transport
NIY05_RS12195	COG1309	transcriptional regulator
NIY05_RS12215	COG1605	Chorismate mutase
NIY05_RS12225	COG4221	oxidoreductase activity
NIY05_RS12235	COG0308	aminopeptidase N
NIY05_RS12255	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
NIY05_RS12265	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY05_RS12270	COG1454	alcohol dehydrogenase
NIY05_RS12290	COG0531	amino acid
NIY05_RS12295	COG4303	Ethanolamine ammonia lyase large subunit
NIY05_RS12300	COG4302	ethanolamine ammonia-lyase activity
NIY05_RS12305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY05_RS12305	COG0519	Catalyzes the synthesis of GMP from XMP
NIY05_RS12310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY05_RS12320	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NIY05_RS12335	COG0697	spore germination
NIY05_RS12340	COG1923	regulation of RNA biosynthetic process
NIY05_RS12350	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIY05_RS12355	COG0802	atpase or kinase
NIY05_RS12375	COG1187	pseudouridine synthase activity
NIY05_RS12390	COG0583	DNA-binding transcription factor activity
NIY05_RS12405	COG2814	Major facilitator Superfamily
NIY05_RS12410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NIY05_RS12435	COG0729	surface antigen
NIY05_RS12455	COG0174	glutamine synthetase
NIY05_RS12460	COG0745	RESPONSE REGULATOR receiver
NIY05_RS12465	COG2205	protein histidine kinase activity
NIY05_RS12475	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NIY05_RS12480	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NIY05_RS12505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY05_RS12510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY05_RS12515	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS12530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY05_RS12535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY05_RS12555	COG0583	DNA-binding transcription factor activity
NIY05_RS12570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY05_RS12580	COG3658	cytochrome
NIY05_RS12585	COG1215	transferase activity, transferring glycosyl groups
NIY05_RS12590	COG0726	polysaccharide deacetylase
NIY05_RS12590	COG1649	PFAM Uncharacterised BCR, COG1649
NIY05_RS12615	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NIY05_RS12620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NIY05_RS12630	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NIY05_RS12655	COG0305	Participates in initiation and elongation during chromosome replication
NIY05_RS12660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIY05_RS12670	COG1305	Transglutaminase-like
NIY05_RS12680	COG2308	Evidence 4 Homologs of previously reported genes of
NIY05_RS12710	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NIY05_RS12715	COG0138	bifunctional purine biosynthesis protein purh
NIY05_RS12720	COG0151	Belongs to the GarS family
NIY05_RS12725	COG1464	Belongs to the NlpA lipoprotein family
NIY05_RS12730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIY05_RS12735	COG2011	ABC-type metal ion transport system permease component
NIY05_RS12740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY05_RS12750	COG1301	dicarboxylic acid transport
NIY05_RS12875	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NIY05_RS12925	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS12945	COG0531	amino acid
NIY05_RS12955	COG1113	amino acid transport
NIY05_RS12995	COG3209	COG3209 Rhs family protein
NIY05_RS13025	COG4269	membrane
NIY05_RS13040	COG1902	pentaerythritol trinitrate reductase activity
NIY05_RS13040	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY05_RS13050	COG5001	Diguanylate cyclase
NIY05_RS13050	COG2203	Gaf domain
NIY05_RS13050	COG3706	GGDEF domain
NIY05_RS13050	COG4251	negative regulation of phosphorylation
NIY05_RS13060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY05_RS13080	COG4172	Belongs to the ABC transporter superfamily
NIY05_RS13085	COG4239	(ABC) transporter, permease
NIY05_RS13090	COG4174	ABC transporter (Permease)
NIY05_RS13100	COG1388	LysM domain
NIY05_RS13100	COG0741	lytic transglycosylase activity
NIY05_RS13100	COG1388	LysM domain
NIY05_RS13100	COG0741	lytic transglycosylase activity
NIY05_RS13105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY05_RS13145	COG0583	DNA-binding transcription factor activity
NIY05_RS13150	COG1279	arginine transmembrane transporter activity
NIY05_RS13170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY05_RS13175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY05_RS13180	COG0006	proline dipeptidase activity
NIY05_RS13265	COG0741	lytic transglycosylase activity
NIY05_RS13265	COG1196	nuclear chromosome segregation
NIY05_RS13265	COG0739	heme binding
NIY05_RS13325	COG4695	Portal protein
NIY05_RS13425	COG0305	Participates in initiation and elongation during chromosome replication
NIY05_RS13445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIY05_RS13500	COG2194	sulfuric ester hydrolase activity
NIY05_RS13545	COG0739	heme binding
NIY05_RS13870	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIY05_RS13895	COG3384	dioxygenase
NIY05_RS13905	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NIY05_RS13910	COG2878	Part of a membrane complex involved in electron transport
NIY05_RS13915	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIY05_RS13940	COG0768	penicillin binding
NIY05_RS13945	COG0742	ribosomal rna small subunit methyltransferase
NIY05_RS13960	COG0830	nickel cation binding
NIY05_RS13970	COG0804	urea catabolic process
NIY05_RS14010	COG1253	flavin adenine dinucleotide binding
NIY05_RS14015	COG2851	Citrate transporter
NIY05_RS14065	COG1773	rubredoxin
NIY05_RS14070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NIY05_RS14080	COG0583	DNA-binding transcription factor activity
NIY05_RS14105	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NIY05_RS14110	COG4181	ATPase activity
NIY05_RS14155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NIY05_RS14175	COG0306	phosphate transporter
NIY05_RS14185	COG3958	Transketolase
NIY05_RS14190	COG3959	Transketolase, thiamine diphosphate binding domain
NIY05_RS14195	COG2271	Major facilitator Superfamily
NIY05_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS14205	COG0583	DNA-binding transcription factor activity
NIY05_RS14220	COG2223	nitrite transmembrane transporter activity
NIY05_RS14225	COG2207	Transcriptional regulator
NIY05_RS14230	COG2066	Belongs to the glutaminase family
NIY05_RS14235	COG0242	peptide deformylase activity
NIY05_RS14240	COG0477	Major facilitator Superfamily
NIY05_RS14250	COG0028	Belongs to the TPP enzyme family
NIY05_RS14265	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS14270	COG2267	carboxylic ester hydrolase activity
NIY05_RS14280	COG2271	Major facilitator Superfamily
NIY05_RS14285	COG0446	pyridine nucleotide-disulphide oxidoreductase
NIY05_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS14315	COG1414	Transcriptional regulator
NIY05_RS14330	COG1024	Enoyl-CoA hydratase
NIY05_RS14340	COG1215	transferase activity, transferring glycosyl groups
NIY05_RS14345	COG1649	PFAM Uncharacterised BCR, COG1649
NIY05_RS14345	COG0726	polysaccharide deacetylase
NIY05_RS14355	COG4681	YaeQ
NIY05_RS14365	COG0523	cobalamin synthesis protein
NIY05_RS14375	COG1607	acyl-coa hydrolase
NIY05_RS14385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY05_RS14390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NIY05_RS14395	COG1309	transcriptional regulator
NIY05_RS14420	COG2040	homocysteine
NIY05_RS14425	COG0531	amino acid
NIY05_RS14480	COG1595	DNA-templated transcription, initiation
NIY05_RS14490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY05_RS14495	COG0477	Major facilitator Superfamily
NIY05_RS14515	COG0084	hydrolase, TatD family'
NIY05_RS14550	COG0629	single-stranded DNA binding
NIY05_RS14605	COG0582	viral genome integration into host DNA
NIY05_RS14635	COG1061	Type III restriction enzyme res subunit
NIY05_RS14645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
NIY05_RS14650	COG1192	Involved in chromosome partitioning
NIY05_RS14660	COG1061	Type III restriction enzyme res subunit
NIY05_RS14750	COG0592	DNA-directed DNA polymerase activity
NIY05_RS14790	COG2026	Addiction module toxin, RelE StbE family
NIY05_RS14940	COG3755	Protein conserved in bacteria
NIY05_RS14985	COG1484	DNA-dependent DNA replication
NIY05_RS15075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIY05_RS15145	COG0405	Gamma-glutamyltransferase
NIY05_RS15150	COG2814	Major facilitator Superfamily
NIY05_RS15160	COG2050	protein possibly involved in aromatic compounds catabolism
NIY05_RS15175	COG1090	epimerase
NIY05_RS15195	COG0420	3'-5' exonuclease activity
NIY05_RS15220	COG0735	belongs to the Fur family
NIY05_RS15225	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NIY05_RS15245	COG0121	glutamine amidotransferase
NIY05_RS15260	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY05_RS15270	COG0210	DNA helicase
NIY05_RS15275	COG2885	chlorophyll binding
NIY05_RS15280	COG0204	Acyl-transferase
NIY05_RS15295	COG2894	cell division
NIY05_RS15320	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS15325	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NIY05_RS15325	COG1674	ftsk spoiiie
NIY05_RS15330	COG0492	ferredoxin-NADP+ reductase activity
NIY05_RS15335	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NIY05_RS15345	COG0456	acetyltransferase
NIY05_RS15390	COG1981	membrane
NIY05_RS15405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY05_RS15405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NIY05_RS15425	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS15435	COG0657	acetylesterase activity
NIY05_RS15445	COG0473	3-isopropylmalate dehydrogenase activity
NIY05_RS15450	COG0583	DNA-binding transcription factor activity
NIY05_RS15470	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NIY05_RS15495	COG0564	pseudouridine synthase activity
NIY05_RS15505	COG0358	DNA primase activity
NIY05_RS15520	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NIY05_RS15550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIY05_RS15580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NIY05_RS15590	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NIY05_RS15590	COG0352	thiamine-phosphate diphosphorylase activity
NIY05_RS15590	COG0351	phosphomethylpyrimidine kinase
NIY05_RS15595	COG1652	LysM domain
NIY05_RS15620	COG1399	metal-binding, possibly nucleic acid-binding protein
NIY05_RS15625	COG3101	peptidyl-lysine hydroxylation
NIY05_RS15630	COG0009	L-threonylcarbamoyladenylate synthase
NIY05_RS15635	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIY05_RS15640	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIY05_RS15655	COG4106	trans-aconitate 2-methyltransferase activity
NIY05_RS15670	COG2226	methyltransferase
NIY05_RS15670	COG0596	Alpha beta hydrolase
NIY05_RS15670	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY05_RS15675	COG1877	trehalose-phosphatase activity
NIY05_RS15680	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
NIY05_RS15685	COG2223	nitrite transmembrane transporter activity
NIY05_RS15705	COG1196	nuclear chromosome segregation
NIY05_RS15715	COG0730	response to heat
NIY05_RS15730	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIY05_RS15740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY05_RS15800	COG0489	protein tyrosine kinase activity
NIY05_RS15810	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY05_RS15810	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY05_RS15840	COG2515	1-aminocyclopropane-1-carboxylate deaminase
NIY05_RS15845	COG2081	HI0933 family
NIY05_RS15855	COG0668	transmembrane transport
NIY05_RS15875	COG0583	DNA-binding transcription factor activity
NIY05_RS15895	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NIY05_RS15900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY05_RS15930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NIY05_RS15970	COG0745	RESPONSE REGULATOR receiver
NIY05_RS15990	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIY05_RS16000	COG2205	protein histidine kinase activity
NIY05_RS16070	COG4993	Dehydrogenase
NIY05_RS16095	COG0384	phenazine biosynthesis protein PhzF
NIY05_RS16120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NIY05_RS16135	COG0583	DNA-binding transcription factor activity
NIY05_RS16165	COG0583	DNA-binding transcription factor activity
NIY05_RS16180	COG0583	DNA-binding transcription factor activity
NIY05_RS16185	COG1053	succinate dehydrogenase
NIY05_RS16195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
NIY05_RS16200	COG2814	Major facilitator Superfamily
NIY05_RS16205	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS16210	COG0583	DNA-binding transcription factor activity
NIY05_RS16215	COG1063	alcohol dehydrogenase
NIY05_RS16245	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NIY05_RS16250	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIY05_RS16255	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY05_RS16270	COG3667	copper resistance
NIY05_RS16275	COG2132	Multicopper oxidase
NIY05_RS16285	COG0561	phosphatase activity
NIY05_RS16290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NIY05_RS16315	COG1214	PFAM Peptidase M22, glycoprotease
NIY05_RS16365	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NIY05_RS16375	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIY05_RS16380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NIY05_RS16385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIY05_RS16445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NIY05_RS16455	COG1846	Transcriptional regulator
NIY05_RS16460	COG1764	response to oxidative stress
NIY05_RS16500	COG0037	tRNA processing
NIY05_RS16510	COG0248	Ppx GppA phosphatase
NIY05_RS16540	COG0072	phenylalanine-tRNA ligase activity
NIY05_RS16585	COG1238	metal cluster binding
NIY05_RS16590	COG0625	glutathione transferase activity
NIY05_RS16605	COG0318	PFAM AMP-dependent synthetase and ligase
NIY05_RS16610	COG3028	Belongs to the UPF0307 family
NIY05_RS16615	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NIY05_RS16635	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NIY05_RS16640	COG0617	tRNA 3'-terminal CCA addition
NIY05_RS16645	COG1555	photosystem II stabilization
NIY05_RS16650	COG3956	TIGRFAM MazG family protein
NIY05_RS16660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIY05_RS16680	COG2205	protein histidine kinase activity
NIY05_RS16680	COG5002	protein histidine kinase activity
NIY05_RS16680	COG0784	Response regulator, receiver
NIY05_RS16685	COG1024	Enoyl-CoA hydratase
NIY05_RS16690	COG2084	Dehydrogenase
NIY05_RS16695	COG3622	Belongs to the hyi family
NIY05_RS16725	COG0697	spore germination
NIY05_RS16735	COG2814	Major facilitator Superfamily
NIY05_RS16740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIY05_RS16750	COG0583	DNA-binding transcription factor activity
NIY05_RS16760	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NIY05_RS16775	COG0084	hydrolase, TatD family'
NIY05_RS16790	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIY05_RS16820	COG0440	acetolactate synthase activity
NIY05_RS16825	COG0028	Belongs to the TPP enzyme family
NIY05_RS16850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NIY05_RS16855	COG0577	efflux transmembrane transporter activity
NIY05_RS16855	COG1136	(ABC) transporter
NIY05_RS16860	COG1538	Outer membrane efflux protein
NIY05_RS16875	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NIY05_RS16880	COG1162	GTPase activity
NIY05_RS16890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NIY05_RS16910	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NIY05_RS16915	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS16955	COG2986	histidine ammonia-lyase
NIY05_RS16970	COG0318	PFAM AMP-dependent synthetase and ligase
NIY05_RS16980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY05_RS17025	COG1426	Protein conserved in bacteria
NIY05_RS17060	COG0793	Belongs to the peptidase S41A family
NIY05_RS17075	COG2267	carboxylic ester hydrolase activity
NIY05_RS17085	COG1012	belongs to the aldehyde dehydrogenase family
NIY05_RS17090	COG3265	gluconokinase activity
NIY05_RS17100	COG0800	Aldolase
NIY05_RS17110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIY05_RS17115	COG0280	phosphate acetyltransferase
NIY05_RS17115	COG0857	belongs to the CobB CobQ family
NIY05_RS17120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY05_RS17120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
NIY05_RS17140	COG0740	serine-type endopeptidase activity
NIY05_RS17150	COG4774	siderophore transport
NIY05_RS17160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NIY05_RS17170	COG2813	Specifically methylates the guanine in position
NIY05_RS17170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NIY05_RS17270	COG0788	formyltetrahydrofolate deformylase activity
NIY05_RS17295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY05_RS17295	COG4651	solute:proton antiporter activity
NIY05_RS17315	COG0724	RNA recognition motif
NIY05_RS17320	COG0210	DNA helicase
NIY05_RS17345	COG1733	regulation of RNA biosynthetic process
NIY05_RS17355	COG2900	Belongs to the SlyX family
NIY05_RS17360	COG0488	(ABC) transporter
NIY05_RS17365	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS17370	COG1560	Kdo2-lipid A biosynthetic process
NIY05_RS17380	COG1301	dicarboxylic acid transport
NIY05_RS17435	COG0473	3-isopropylmalate dehydrogenase activity
NIY05_RS17500	COG0583	DNA-binding transcription factor activity
NIY05_RS17510	COG0625	glutathione transferase activity
NIY05_RS17515	COG2378	regulation of single-species biofilm formation
NIY05_RS17520	COG0546	phosphoglycolate phosphatase activity
NIY05_RS17530	COG1530	ribonuclease E activity
NIY05_RS17535	COG0318	PFAM AMP-dependent synthetase and ligase
NIY05_RS17550	COG0583	DNA-binding transcription factor activity
NIY05_RS17555	COG4221	oxidoreductase activity
NIY05_RS17560	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NIY05_RS17570	COG0534	Mate efflux family protein
NIY05_RS17585	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NIY05_RS17625	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NIY05_RS17630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NIY05_RS17645	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NIY05_RS17655	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
NIY05_RS17655	COG0644	oxidoreductase
NIY05_RS17660	COG0425	Belongs to the sulfur carrier protein TusA family
NIY05_RS17665	COG4535	Mg2 and Co2 transporter CorC
NIY05_RS17675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIY05_RS17695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIY05_RS17700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NIY05_RS17700	COG0475	glutathione-regulated potassium exporter activity
NIY05_RS17705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIY05_RS17715	COG0484	heat shock protein binding
NIY05_RS17720	COG0789	Transcriptional regulator
NIY05_RS17725	COG0598	Magnesium transport protein CorA
NIY05_RS17740	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
NIY05_RS17745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NIY05_RS17750	COG1074	ATP-dependent DNA helicase activity
NIY05_RS17755	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NIY05_RS17775	COG2226	methyltransferase
NIY05_RS17790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NIY05_RS17795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIY05_RS17810	COG2111	Na H antiporter
NIY05_RS17810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NIY05_RS17815	COG1006	Multisubunit Na H antiporter MnhC subunit
NIY05_RS17820	COG0651	ATP synthesis coupled electron transport
NIY05_RS17825	COG1863	multisubunit Na H antiporter MnhE subunit
NIY05_RS17830	COG2212	antiporter activity
NIY05_RS17835	COG1320	monovalent cation:proton antiporter activity
NIY05_RS17850	COG0195	Participates in both transcription termination and antitermination
NIY05_RS17900	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NIY05_RS17905	COG0237	dephospho-CoA kinase activity
NIY05_RS17915	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIY05_RS17930	COG0497	DNA recombination
NIY05_RS17940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIY05_RS17970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NIY05_RS17970	COG2169	Transcriptional regulator
NIY05_RS17975	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIY05_RS18040	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
NIY05_RS18055	COG0326	Molecular chaperone. Has ATPase activity
NIY05_RS18070	COG2056	Na+-H+ antiporter family
NIY05_RS18075	COG0596	Alpha beta hydrolase
NIY05_RS18170	COG0546	phosphoglycolate phosphatase activity
NIY05_RS18175	COG1716	ATPase activity
NIY05_RS18220	COG0181	hydroxymethylbilane synthase activity
NIY05_RS18230	COG3275	phosphorelay sensor kinase activity
NIY05_RS18250	COG1538	Outer membrane efflux protein
NIY05_RS18255	COG0697	spore germination
NIY05_RS18280	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
NIY05_RS18285	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NIY05_RS18290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIY05_RS18295	COG0772	Belongs to the SEDS family
NIY05_RS18320	COG4974	Belongs to the 'phage' integrase family
NIY05_RS18325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY05_RS18335	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NIY05_RS18345	COG2197	response regulator
NIY05_RS18360	COG0793	Belongs to the peptidase S41A family
NIY05_RS18365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIY05_RS18370	COG0795	lipopolysaccharide-transporting ATPase activity
NIY05_RS18410	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY05_RS18410	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIY05_RS18420	COG0004	ammonium transporteR
NIY05_RS18425	COG0347	Belongs to the P(II) protein family
NIY05_RS18485	COG0659	secondary active sulfate transmembrane transporter activity
NIY05_RS18490	COG0589	response to stress
NIY05_RS18525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NIY05_RS18535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIY05_RS18555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NIY05_RS18570	COG0318	PFAM AMP-dependent synthetase and ligase
NIY05_RS18580	COG0477	Major facilitator Superfamily
NIY05_RS18585	COG2860	membrane
NIY05_RS18595	COG1253	flavin adenine dinucleotide binding
NIY05_RS18615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIY05_RS18655	COG0655	NAD(P)H dehydrogenase (quinone) activity
NIY05_RS18665	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NIY05_RS18735	COG0758	DNA mediated transformation
NIY05_RS18745	COG0697	spore germination
NIY05_RS18750	COG1309	transcriptional regulator
NIY05_RS18765	COG0386	Belongs to the glutathione peroxidase family
NIY05_RS18830	COG1121	(ABC) transporter
NIY05_RS18835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NIY05_RS18840	COG1280	lysine exporter protein (LysE YggA)
NIY05_RS18845	COG2837	iron assimilation
NIY05_RS18855	COG0281	malic enzyme
NIY05_RS18900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NIY05_RS18900	COG0519	Catalyzes the synthesis of GMP from XMP
NIY05_RS18905	COG4399	Belongs to the UPF0754 family
NIY05_RS18910	COG2259	Doxx family
NIY05_RS18915	COG0586	Pfam SNARE associated Golgi protein
NIY05_RS18930	COG1192	Involved in chromosome partitioning
NIY05_RS18940	COG0271	Belongs to the BolA IbaG family
NIY05_RS18960	COG2267	carboxylic ester hydrolase activity
NIY05_RS18980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIY05_RS18980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NIY05_RS18980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
NIY05_RS18980	COG3321	synthase
NIY05_RS18985	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS18995	COG2197	response regulator
NIY05_RS19005	COG3916	Acyl-homoserine-lactone synthase
NIY05_RS19010	COG0477	Major facilitator Superfamily
NIY05_RS19015	COG1024	Enoyl-CoA hydratase
NIY05_RS19020	COG1024	Enoyl-CoA hydratase
NIY05_RS19025	COG1960	acyl-CoA dehydrogenase activity
NIY05_RS19030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NIY05_RS19050	COG1113	amino acid transport
NIY05_RS19055	COG1113	amino acid transport
NIY05_RS19060	COG0251	oxidation-reduction process
NIY05_RS19100	COG0564	pseudouridine synthase activity
NIY05_RS19160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NIY05_RS19175	COG1802	Transcriptional regulator
NIY05_RS19185	COG1448	Aminotransferase
NIY05_RS19190	COG0277	FAD linked oxidase domain protein
NIY05_RS19200	COG2186	Transcriptional regulator
NIY05_RS19210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIY05_RS19215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NIY05_RS19230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NIY05_RS19235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NIY05_RS19240	COG1216	Glycosyl transferase, family 2
NIY05_RS19270	COG2089	acid synthase
NIY05_RS19285	COG1083	cytidylyl-transferase
NIY05_RS19290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NIY05_RS19295	COG1086	Polysaccharide biosynthesis protein
NIY05_RS19300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
NIY05_RS19305	COG1596	polysaccharide export
NIY05_RS19330	COG0728	peptidoglycan biosynthetic process
NIY05_RS19335	COG3023	N-Acetylmuramoyl-L-alanine amidase
NIY05_RS19390	COG0546	phosphoglycolate phosphatase activity
NIY05_RS19395	COG1028	Short-chain dehydrogenase reductase Sdr
NIY05_RS19415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY05_RS19420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NIY05_RS19425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NIY05_RS19430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NIY05_RS19435	COG1116	anion transmembrane transporter activity
NIY05_RS19440	COG1309	transcriptional regulator
NIY05_RS19445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIY05_RS19455	COG0196	riboflavin kinase activity
NIY05_RS19460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIY05_RS19470	COG1047	Peptidyl-prolyl cis-trans
NIY05_RS19510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIY05_RS19515	COG0657	acetylesterase activity
NIY05_RS19535	COG0583	DNA-binding transcription factor activity
NIY05_RS19565	COG2951	lytic endotransglycosylase activity
NIY05_RS19570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIY05_RS19585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NIY05_RS19595	COG0671	phosphoesterase, PA-phosphatase related
NIY05_RS19600	COG0861	Integral membrane protein TerC family
NIY05_RS19610	COG0754	glutathionylspermidine amidase activity
NIY05_RS19620	COG0402	S-adenosylhomocysteine deaminase activity
NIY05_RS19635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NIY05_RS19640	COG1230	cation diffusion facilitator family transporter
NIY05_RS19655	COG0706	membrane insertase activity