locus-tag	class	description
L2Z27_RS00055	COG1966	Carbon starvation protein
L2Z27_RS00100	COG1067	ATP-dependent peptidase activity
L2Z27_RS00135	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
L2Z27_RS00165	COG3328	transposase activity
L2Z27_RS00175	COG0616	signal peptide processing
L2Z27_RS00180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
L2Z27_RS00190	COG0573	inorganic phosphate transmembrane transporter activity
L2Z27_RS00205	COG3961	Belongs to the TPP enzyme family
L2Z27_RS00210	COG1522	sequence-specific DNA binding
L2Z27_RS00220	COG0076	glutamate decarboxylase activity
L2Z27_RS00225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z27_RS00235	COG1309	transcriptional regulator
L2Z27_RS00250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z27_RS00285	COG0352	thiamine-phosphate diphosphorylase activity
L2Z27_RS00310	COG0612	Peptidase, M16
L2Z27_RS00320	COG1823	symporter activity
L2Z27_RS00325	COG0583	DNA-binding transcription factor activity
L2Z27_RS00330	COG0477	Major facilitator Superfamily
L2Z27_RS00355	COG1187	pseudouridine synthase activity
L2Z27_RS00370	COG1686	Belongs to the peptidase S11 family
L2Z27_RS00375	COG1252	NADH dehydrogenase
L2Z27_RS00385	COG0415	Belongs to the DNA photolyase family
L2Z27_RS00400	COG1215	transferase activity, transferring glycosyl groups
L2Z27_RS00430	COG2070	2-Nitropropane dioxygenase
L2Z27_RS00485	COG0556	nucleotide-excision repair
L2Z27_RS00505	COG0436	Aminotransferase
L2Z27_RS00535	COG4221	oxidoreductase activity
L2Z27_RS00545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
L2Z27_RS00550	COG1381	Involved in DNA repair and RecF pathway recombination
L2Z27_RS00560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
L2Z27_RS00575	COG0681	Belongs to the peptidase S26 family
L2Z27_RS00590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z27_RS00610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
L2Z27_RS00615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
L2Z27_RS00620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
L2Z27_RS00630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
L2Z27_RS00635	COG4208	sulfate ABC transporter
L2Z27_RS00640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
L2Z27_RS00645	COG0583	DNA-binding transcription factor activity
L2Z27_RS00650	COG4625	pathogenesis
L2Z27_RS00665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
L2Z27_RS00680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
L2Z27_RS00690	COG1051	belongs to the nudix hydrolase family
L2Z27_RS00690	COG1056	cytidyltransferase-related domain
L2Z27_RS00695	COG1024	Enoyl-CoA hydratase
L2Z27_RS00705	COG2814	Major facilitator Superfamily
L2Z27_RS00710	COG0047	phosphoribosylformylglycinamidine synthase activity
L2Z27_RS00710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
L2Z27_RS00730	COG1473	amidohydrolase
L2Z27_RS00735	COG0824	Thioesterase
L2Z27_RS00755	COG0823	Involved in the tonB-independent uptake of proteins
L2Z27_RS00775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z27_RS00810	COG0628	permease
L2Z27_RS00820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
L2Z27_RS00825	COG0596	Alpha beta hydrolase
L2Z27_RS00830	COG0616	signal peptide processing
L2Z27_RS00830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
L2Z27_RS00840	COG0658	competence protein
L2Z27_RS00840	COG2333	competence protein COMEC
L2Z27_RS00845	COG1136	(ABC) transporter
L2Z27_RS00850	COG4591	ABC-type transport system involved in lipoprotein release permease component
L2Z27_RS00885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS00905	COG0463	Glycosyl transferase, family 2
L2Z27_RS00935	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
L2Z27_RS00940	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS00950	COG0019	diaminopimelate decarboxylase activity
L2Z27_RS00960	COG1113	amino acid transport
L2Z27_RS00975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
L2Z27_RS00985	COG3339	Conserved Protein
L2Z27_RS00990	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
L2Z27_RS00995	COG0243	molybdopterin cofactor binding
L2Z27_RS01000	COG1929	Belongs to the glycerate kinase type-1 family
L2Z27_RS01015	COG0778	Nitroreductase
L2Z27_RS01050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z27_RS01065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
L2Z27_RS01085	COG0741	lytic transglycosylase activity
L2Z27_RS01105	COG0584	glycerophosphoryl diester phosphodiesterase
L2Z27_RS01135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z27_RS01140	COG1597	lipid kinase activity
L2Z27_RS01155	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
L2Z27_RS01160	COG0477	Major facilitator Superfamily
L2Z27_RS01210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
L2Z27_RS01215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z27_RS01240	COG0505	Belongs to the CarA family
L2Z27_RS01260	COG0589	response to stress
L2Z27_RS01275	COG2843	Capsule synthesis protein
L2Z27_RS01295	COG2321	neutral zinc metallopeptidase
L2Z27_RS01300	COG2354	Protein conserved in bacteria
L2Z27_RS01320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z27_RS01345	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
L2Z27_RS01350	COG1053	succinate dehydrogenase
L2Z27_RS01355	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
L2Z27_RS01360	COG2009	succinate dehydrogenase
L2Z27_RS01400	COG2921	Belongs to the UPF0250 family
L2Z27_RS01405	COG0321	lipoyl(octanoyl) transferase activity
L2Z27_RS01420	COG0531	amino acid
L2Z27_RS01430	COG1733	regulation of RNA biosynthetic process
L2Z27_RS01435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
L2Z27_RS01440	COG1648	precorrin-2 dehydrogenase activity
L2Z27_RS01440	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
L2Z27_RS01455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
L2Z27_RS01485	COG0671	phosphoesterase, PA-phosphatase related
L2Z27_RS01490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS01500	COG1538	Outer membrane efflux protein
L2Z27_RS01505	COG0393	Putative heavy-metal-binding
L2Z27_RS01510	COG0393	Putative heavy-metal-binding
L2Z27_RS01520	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS01530	COG0525	valine-tRNA ligase activity
L2Z27_RS01550	COG0583	DNA-binding transcription factor activity
L2Z27_RS01555	COG0004	ammonium transporteR
L2Z27_RS01565	COG0642	Histidine kinase
L2Z27_RS01570	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS01575	COG2194	sulfuric ester hydrolase activity
L2Z27_RS01595	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z27_RS01610	COG2315	Protein conserved in bacteria
L2Z27_RS01615	COG0142	geranyltranstransferase activity
L2Z27_RS01620	COG2828	Protein conserved in bacteria
L2Z27_RS01625	COG1113	amino acid transport
L2Z27_RS01645	COG2207	Transcriptional regulator
L2Z27_RS01670	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z27_RS01680	COG0560	Phosphoserine phosphatase
L2Z27_RS01690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z27_RS01700	COG1530	ribonuclease E activity
L2Z27_RS01705	COG0424	maF-like protein
L2Z27_RS01710	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
L2Z27_RS01715	COG1792	Involved in formation and maintenance of cell shape
L2Z27_RS01720	COG1077	Cell shape determining protein MreB Mrl
L2Z27_RS01725	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z27_RS01735	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
L2Z27_RS01775	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
L2Z27_RS01780	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z27_RS01785	COG1752	Esterase of the alpha-beta hydrolase superfamily
L2Z27_RS01790	COG1115	amino acid carrier protein
L2Z27_RS01810	COG2814	Major facilitator Superfamily
L2Z27_RS01815	COG1289	transmembrane transporter activity
L2Z27_RS01825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
L2Z27_RS01865	COG1376	ErfK ybiS ycfS ynhG family protein
L2Z27_RS01870	COG2832	Protein of unknown function (DUF454)
L2Z27_RS01880	COG5510	response to toxic substance
L2Z27_RS01900	COG0840	transmembrane signaling receptor activity
L2Z27_RS01940	COG3422	double-strand break repair
L2Z27_RS01945	COG2824	Alkylphosphonate utilization operon protein PhnA
L2Z27_RS01950	COG3189	MarR family transcriptional regulator
L2Z27_RS01960	COG0354	folic acid binding
L2Z27_RS01965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z27_RS01975	COG0679	Auxin Efflux Carrier
L2Z27_RS01980	COG1902	pentaerythritol trinitrate reductase activity
L2Z27_RS02000	COG2094	Belongs to the DNA glycosylase MPG family
L2Z27_RS02025	COG1217	gtp-binding protein TYPA
L2Z27_RS02030	COG2233	PERMEase
L2Z27_RS02040	COG0833	amino acid
L2Z27_RS02045	COG1690	Belongs to the RtcB family
L2Z27_RS02055	COG2885	chlorophyll binding
L2Z27_RS02055	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
L2Z27_RS02065	COG0183	Belongs to the thiolase family
L2Z27_RS02085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z27_RS02105	COG2207	Transcriptional regulator
L2Z27_RS02110	COG0183	Belongs to the thiolase family
L2Z27_RS02140	COG1272	protein, Hemolysin III
L2Z27_RS02145	COG0477	Major facilitator Superfamily
L2Z27_RS02160	COG0450	alkyl hydroperoxide reductase
L2Z27_RS02180	COG0285	dihydrofolate synthase activity
L2Z27_RS02230	COG2096	Adenosyltransferase
L2Z27_RS02250	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
L2Z27_RS02255	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS02260	COG2205	protein histidine kinase activity
L2Z27_RS02270	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS02275	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS02280	COG0583	DNA-binding transcription factor activity
L2Z27_RS02285	COG0625	glutathione transferase activity
L2Z27_RS02330	COG2826	transposase and inactivated derivatives, IS30 family
L2Z27_RS02360	COG0438	transferase activity, transferring glycosyl groups
L2Z27_RS02365	COG0463	Glycosyl transferase, family 2
L2Z27_RS02370	COG0726	polysaccharide deacetylase
L2Z27_RS02390	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
L2Z27_RS02395	COG2205	protein histidine kinase activity
L2Z27_RS02425	COG1862	Preprotein translocase
L2Z27_RS02435	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
L2Z27_RS02440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
L2Z27_RS02450	COG3781	membrane
L2Z27_RS02455	COG0613	PHP domain protein
L2Z27_RS02465	COG2350	Protein conserved in bacteria
L2Z27_RS02495	COG1607	acyl-coa hydrolase
L2Z27_RS02565	COG2199	diguanylate cyclase activity
L2Z27_RS02575	COG1408	metallophosphoesterase
L2Z27_RS02580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z27_RS02590	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
L2Z27_RS02610	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
L2Z27_RS02615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
L2Z27_RS02630	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L2Z27_RS02640	COG2969	positive regulation of protein catabolic process
L2Z27_RS02660	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS02665	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z27_RS02680	COG1309	transcriptional regulator
L2Z27_RS02685	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS02730	COG1183	phosphatidylcholine synthase activity
L2Z27_RS02735	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
L2Z27_RS02765	COG1196	nuclear chromosome segregation
L2Z27_RS02765	COG0739	heme binding
L2Z27_RS02765	COG0741	lytic transglycosylase activity
L2Z27_RS02775	COG1702	phosphate starvation-inducible protein PhoH
L2Z27_RS02810	COG1295	ribonuclease BN
L2Z27_RS02815	COG0697	spore germination
L2Z27_RS02820	COG2169	Transcriptional regulator
L2Z27_RS02825	COG0179	Fumarylacetoacetate (FAA) hydrolase
L2Z27_RS02870	COG0557	exoribonuclease II activity
L2Z27_RS02875	COG0339	signal peptide processing
L2Z27_RS02880	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
L2Z27_RS02910	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
L2Z27_RS02915	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS03070	COG0626	cystathionine gamma-synthase activity
L2Z27_RS03075	COG0433	COG0433 Predicted ATPase
L2Z27_RS03080	COG1017	nitric oxide dioxygenase activity
L2Z27_RS03080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z27_RS03085	COG1959	2 iron, 2 sulfur cluster binding
L2Z27_RS03100	COG1301	dicarboxylic acid transport
L2Z27_RS03105	COG1946	Acyl-CoA thioesterase
L2Z27_RS03125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
L2Z27_RS03130	COG1040	competence protein
L2Z27_RS03135	COG0494	nUDIX hydrolase
L2Z27_RS03145	COG0598	Magnesium transport protein CorA
L2Z27_RS03155	COG2854	intermembrane phospholipid transfer
L2Z27_RS03165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
L2Z27_RS03170	COG1127	ABC transporter
L2Z27_RS03180	COG0513	Belongs to the DEAD box helicase family
L2Z27_RS03200	COG0408	coproporphyrinogen oxidase activity
L2Z27_RS03215	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS03225	COG1983	PspC domain protein
L2Z27_RS03230	COG0517	IMP dehydrogenase activity
L2Z27_RS03275	COG0583	DNA-binding transcription factor activity
L2Z27_RS03315	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS03330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z27_RS03335	COG0833	amino acid
L2Z27_RS03365	COG1192	Involved in chromosome partitioning
L2Z27_RS03370	COG0628	permease
L2Z27_RS03380	COG1289	transmembrane transporter activity
L2Z27_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z27_RS03400	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
L2Z27_RS03410	COG0277	FAD linked oxidase domain protein
L2Z27_RS03415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
L2Z27_RS03440	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
L2Z27_RS03445	COG5380	lipid catabolic process
L2Z27_RS03465	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
L2Z27_RS03515	COG0194	GDP metabolic process
L2Z27_RS03530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z27_RS03550	COG3307	-O-antigen
L2Z27_RS03570	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
L2Z27_RS03575	COG1704	LemA family
L2Z27_RS03585	COG0493	'glutamate synthase
L2Z27_RS03590	COG0067	glutamate synthase
L2Z27_RS03590	COG0069	glutamate synthase activity
L2Z27_RS03590	COG0070	glutamate synthase
L2Z27_RS03640	COG2226	methyltransferase
L2Z27_RS03655	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
L2Z27_RS03660	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
L2Z27_RS03705	COG0833	amino acid
L2Z27_RS03790	COG0488	(ABC) transporter
L2Z27_RS03795	COG2873	o-acetylhomoserine
L2Z27_RS03800	COG4221	oxidoreductase activity
L2Z27_RS03805	COG0659	secondary active sulfate transmembrane transporter activity
L2Z27_RS03830	COG0427	acetyl-CoA hydrolase
L2Z27_RS03860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
L2Z27_RS03890	COG2329	Antibiotic biosynthesis monooxygenase
L2Z27_RS03905	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
L2Z27_RS03970	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z27_RS03975	COG1733	regulation of RNA biosynthetic process
L2Z27_RS04010	COG0667	Aldo Keto reductase
L2Z27_RS04030	COG0583	DNA-binding transcription factor activity
L2Z27_RS04035	COG2814	Major facilitator Superfamily
L2Z27_RS04065	COG1335	isochorismatase
L2Z27_RS04075	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS04080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
L2Z27_RS04090	COG1113	amino acid transport
L2Z27_RS04100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z27_RS04115	COG2814	Major facilitator Superfamily
L2Z27_RS04125	COG0352	thiamine-phosphate diphosphorylase activity
L2Z27_RS04125	COG0351	phosphomethylpyrimidine kinase
L2Z27_RS04125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z27_RS04145	COG1309	transcriptional regulator
L2Z27_RS04150	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
L2Z27_RS04170	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z27_RS04180	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z27_RS04185	COG3162	membrane
L2Z27_RS04190	COG2198	Histidine kinase
L2Z27_RS04190	COG2205	protein histidine kinase activity
L2Z27_RS04190	COG0784	Response regulator, receiver
L2Z27_RS04215	COG3328	transposase activity
L2Z27_RS04220	COG1522	sequence-specific DNA binding
L2Z27_RS04225	COG1335	isochorismatase
L2Z27_RS04230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z27_RS04240	COG0668	transmembrane transport
L2Z27_RS04245	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z27_RS04250	COG1519	Transferase
L2Z27_RS04255	COG1902	pentaerythritol trinitrate reductase activity
L2Z27_RS04275	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
L2Z27_RS04300	COG0426	domain, Protein
L2Z27_RS04300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z27_RS04305	COG4774	siderophore transport
L2Z27_RS04310	COG2119	membrane
L2Z27_RS04320	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z27_RS04330	COG4942	peptidase
L2Z27_RS04345	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
L2Z27_RS04355	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
L2Z27_RS04375	COG0189	ligase activity
L2Z27_RS04395	COG0708	Exodeoxyribonuclease III
L2Z27_RS04400	COG1393	Belongs to the ArsC family
L2Z27_RS04415	COG3706	GGDEF domain
L2Z27_RS04450	COG2351	hydroxyisourate hydrolase activity
L2Z27_RS04455	COG2233	PERMEase
L2Z27_RS04465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z27_RS04475	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
L2Z27_RS04480	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS04490	COG3150	esterase
L2Z27_RS04505	COG1388	LysM domain
L2Z27_RS04505	COG0791	NLP P60 protein
L2Z27_RS04520	COG2918	glutathione biosynthetic process
L2Z27_RS04535	COG2733	membrane
L2Z27_RS04540	COG0436	Aminotransferase
L2Z27_RS04545	COG0534	Mate efflux family protein
L2Z27_RS04645	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
L2Z27_RS04650	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
L2Z27_RS04660	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
L2Z27_RS04665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z27_RS04680	COG0010	Belongs to the arginase family
L2Z27_RS04710	COG2188	Transcriptional regulator
L2Z27_RS04720	COG0523	cobalamin synthesis protein
L2Z27_RS04730	COG1113	amino acid transport
L2Z27_RS04740	COG0625	glutathione transferase activity
L2Z27_RS04760	COG1683	Conserved Protein
L2Z27_RS04765	COG0534	Mate efflux family protein
L2Z27_RS04770	COG0385	Bile acid
L2Z27_RS04775	COG1335	isochorismatase
L2Z27_RS04780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z27_RS04800	COG2116	formate transmembrane transporter activity
L2Z27_RS04805	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
L2Z27_RS04810	COG2133	pyrroloquinoline quinone binding
L2Z27_RS04815	COG2983	Belongs to the UPF0260 family
L2Z27_RS04835	COG1194	a g-specific adenine glycosylase
L2Z27_RS04850	COG2818	Glycosylase
L2Z27_RS04855	COG1064	alcohol dehydrogenase
L2Z27_RS04860	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z27_RS04875	COG0583	DNA-binding transcription factor activity
L2Z27_RS04880	COG0656	L-ascorbic acid biosynthetic process
L2Z27_RS04885	COG2814	Major facilitator Superfamily
L2Z27_RS04920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS04935	COG2233	PERMEase
L2Z27_RS04975	COG0733	neurotransmitter:sodium symporter activity
L2Z27_RS05015	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
L2Z27_RS05020	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
L2Z27_RS05025	COG0596	Alpha beta hydrolase
L2Z27_RS05050	COG0488	(ABC) transporter
L2Z27_RS05055	COG0586	Pfam SNARE associated Golgi protein
L2Z27_RS05065	COG0187	DNA topoisomerase II activity
L2Z27_RS05075	COG0592	DNA-directed DNA polymerase activity
L2Z27_RS05100	COG0706	membrane insertase activity
L2Z27_RS05115	COG1230	cation diffusion facilitator family transporter
L2Z27_RS05120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z27_RS05135	COG0402	S-adenosylhomocysteine deaminase activity
L2Z27_RS05145	COG0754	glutathionylspermidine amidase activity
L2Z27_RS05155	COG0861	Integral membrane protein TerC family
L2Z27_RS05160	COG0671	phosphoesterase, PA-phosphatase related
L2Z27_RS05170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
L2Z27_RS05185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
L2Z27_RS05190	COG2951	lytic endotransglycosylase activity
L2Z27_RS05220	COG0583	DNA-binding transcription factor activity
L2Z27_RS05240	COG0657	acetylesterase activity
L2Z27_RS05245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
L2Z27_RS05285	COG1047	Peptidyl-prolyl cis-trans
L2Z27_RS05295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
L2Z27_RS05300	COG0196	riboflavin kinase activity
L2Z27_RS05310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
L2Z27_RS05315	COG1309	transcriptional regulator
L2Z27_RS05320	COG1116	anion transmembrane transporter activity
L2Z27_RS05325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z27_RS05330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z27_RS05335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z27_RS05340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z27_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS05365	COG0546	phosphoglycolate phosphatase activity
L2Z27_RS05420	COG3023	N-Acetylmuramoyl-L-alanine amidase
L2Z27_RS05425	COG0728	peptidoglycan biosynthetic process
L2Z27_RS05465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z27_RS05470	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
L2Z27_RS05475	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
L2Z27_RS05505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
L2Z27_RS05510	COG0110	maltose O-acetyltransferase activity
L2Z27_RS05520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
L2Z27_RS05535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z27_RS05540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z27_RS05550	COG2186	Transcriptional regulator
L2Z27_RS05560	COG0277	FAD linked oxidase domain protein
L2Z27_RS05565	COG1448	Aminotransferase
L2Z27_RS05570	COG1802	Transcriptional regulator
L2Z27_RS05585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
L2Z27_RS05645	COG0564	pseudouridine synthase activity
L2Z27_RS05685	COG0251	oxidation-reduction process
L2Z27_RS05690	COG1113	amino acid transport
L2Z27_RS05695	COG1113	amino acid transport
L2Z27_RS05715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z27_RS05720	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS05725	COG1024	Enoyl-CoA hydratase
L2Z27_RS05730	COG1024	Enoyl-CoA hydratase
L2Z27_RS05735	COG0477	Major facilitator Superfamily
L2Z27_RS05740	COG3916	Acyl-homoserine-lactone synthase
L2Z27_RS05750	COG2197	response regulator
L2Z27_RS05760	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS05765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z27_RS05765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
L2Z27_RS05765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
L2Z27_RS05765	COG3321	synthase
L2Z27_RS05785	COG2267	carboxylic ester hydrolase activity
L2Z27_RS05805	COG0271	Belongs to the BolA IbaG family
L2Z27_RS05815	COG1192	Involved in chromosome partitioning
L2Z27_RS05830	COG0586	Pfam SNARE associated Golgi protein
L2Z27_RS05835	COG2259	Doxx family
L2Z27_RS05840	COG4399	Belongs to the UPF0754 family
L2Z27_RS05845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z27_RS05845	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z27_RS05890	COG0281	malic enzyme
L2Z27_RS05900	COG2837	iron assimilation
L2Z27_RS05905	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS05910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
L2Z27_RS05915	COG1121	(ABC) transporter
L2Z27_RS05980	COG0386	Belongs to the glutathione peroxidase family
L2Z27_RS05995	COG1309	transcriptional regulator
L2Z27_RS06000	COG0697	spore germination
L2Z27_RS06010	COG0758	DNA mediated transformation
L2Z27_RS06080	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
L2Z27_RS06090	COG0655	NAD(P)H dehydrogenase (quinone) activity
L2Z27_RS06130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
L2Z27_RS06150	COG1253	flavin adenine dinucleotide binding
L2Z27_RS06160	COG2860	membrane
L2Z27_RS06165	COG0477	Major facilitator Superfamily
L2Z27_RS06175	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z27_RS06190	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
L2Z27_RS06210	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z27_RS06255	COG0589	response to stress
L2Z27_RS06260	COG0659	secondary active sulfate transmembrane transporter activity
L2Z27_RS06270	COG1002	Type II restriction enzyme, methylase subunits
L2Z27_RS06275	COG1061	Type III restriction enzyme res subunit
L2Z27_RS06350	COG0347	Belongs to the P(II) protein family
L2Z27_RS06355	COG0004	ammonium transporteR
L2Z27_RS06365	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z27_RS06365	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
L2Z27_RS06405	COG0795	lipopolysaccharide-transporting ATPase activity
L2Z27_RS06410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
L2Z27_RS06415	COG0793	Belongs to the peptidase S41A family
L2Z27_RS06430	COG2197	response regulator
L2Z27_RS06440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
L2Z27_RS06450	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
L2Z27_RS06455	COG4974	Belongs to the 'phage' integrase family
L2Z27_RS06480	COG0772	Belongs to the SEDS family
L2Z27_RS06485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z27_RS06490	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
L2Z27_RS06495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
L2Z27_RS06520	COG0697	spore germination
L2Z27_RS06525	COG1538	Outer membrane efflux protein
L2Z27_RS06545	COG3275	phosphorelay sensor kinase activity
L2Z27_RS06555	COG0181	hydroxymethylbilane synthase activity
L2Z27_RS06600	COG1716	ATPase activity
L2Z27_RS06605	COG0546	phosphoglycolate phosphatase activity
L2Z27_RS06700	COG0596	Alpha beta hydrolase
L2Z27_RS06705	COG2056	Na+-H+ antiporter family
L2Z27_RS06720	COG0326	Molecular chaperone. Has ATPase activity
L2Z27_RS06735	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
L2Z27_RS06800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
L2Z27_RS06805	COG2169	Transcriptional regulator
L2Z27_RS06805	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z27_RS06835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
L2Z27_RS06845	COG0497	DNA recombination
L2Z27_RS06860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
L2Z27_RS06870	COG0237	dephospho-CoA kinase activity
L2Z27_RS06875	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
L2Z27_RS06925	COG0195	Participates in both transcription termination and antitermination
L2Z27_RS06940	COG1320	monovalent cation:proton antiporter activity
L2Z27_RS06945	COG2212	antiporter activity
L2Z27_RS06950	COG1863	multisubunit Na H antiporter MnhE subunit
L2Z27_RS06955	COG0651	ATP synthesis coupled electron transport
L2Z27_RS06960	COG1006	Multisubunit Na H antiporter MnhC subunit
L2Z27_RS06965	COG2111	Na H antiporter
L2Z27_RS06965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z27_RS06980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
L2Z27_RS06985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z27_RS07000	COG2226	methyltransferase
L2Z27_RS07020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
L2Z27_RS07025	COG1074	ATP-dependent DNA helicase activity
L2Z27_RS07030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z27_RS07035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z27_RS07050	COG0598	Magnesium transport protein CorA
L2Z27_RS07055	COG0789	Transcriptional regulator
L2Z27_RS07060	COG0484	heat shock protein binding
L2Z27_RS07070	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
L2Z27_RS07075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z27_RS07075	COG0475	glutathione-regulated potassium exporter activity
L2Z27_RS07080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
L2Z27_RS07100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z27_RS07110	COG4535	Mg2 and Co2 transporter CorC
L2Z27_RS07115	COG0425	Belongs to the sulfur carrier protein TusA family
L2Z27_RS07120	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
L2Z27_RS07120	COG0644	oxidoreductase
L2Z27_RS07130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
L2Z27_RS07145	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z27_RS07150	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
L2Z27_RS07190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
L2Z27_RS07205	COG0534	Mate efflux family protein
L2Z27_RS07215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
L2Z27_RS07220	COG4221	oxidoreductase activity
L2Z27_RS07225	COG0583	DNA-binding transcription factor activity
L2Z27_RS07240	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z27_RS07245	COG1530	ribonuclease E activity
L2Z27_RS07255	COG0546	phosphoglycolate phosphatase activity
L2Z27_RS07260	COG2378	regulation of single-species biofilm formation
L2Z27_RS07265	COG0625	glutathione transferase activity
L2Z27_RS07275	COG0583	DNA-binding transcription factor activity
L2Z27_RS07340	COG0473	3-isopropylmalate dehydrogenase activity
L2Z27_RS07395	COG1301	dicarboxylic acid transport
L2Z27_RS07405	COG1560	Kdo2-lipid A biosynthetic process
L2Z27_RS07410	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS07415	COG0488	(ABC) transporter
L2Z27_RS07420	COG2900	Belongs to the SlyX family
L2Z27_RS07430	COG1733	regulation of RNA biosynthetic process
L2Z27_RS07455	COG0210	DNA helicase
L2Z27_RS07460	COG0724	RNA recognition motif
L2Z27_RS07480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z27_RS07480	COG4651	solute:proton antiporter activity
L2Z27_RS07505	COG0788	formyltetrahydrofolate deformylase activity
L2Z27_RS07605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z27_RS07605	COG2813	Specifically methylates the guanine in position
L2Z27_RS07615	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
L2Z27_RS07625	COG4774	siderophore transport
L2Z27_RS07635	COG0740	serine-type endopeptidase activity
L2Z27_RS07655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z27_RS07655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
L2Z27_RS07660	COG0280	phosphate acetyltransferase
L2Z27_RS07660	COG0857	belongs to the CobB CobQ family
L2Z27_RS07665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
L2Z27_RS07680	COG0800	Aldolase
L2Z27_RS07690	COG3265	gluconokinase activity
L2Z27_RS07695	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS07705	COG2267	carboxylic ester hydrolase activity
L2Z27_RS07720	COG0793	Belongs to the peptidase S41A family
L2Z27_RS07755	COG1426	Protein conserved in bacteria
L2Z27_RS07800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
L2Z27_RS07810	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z27_RS07825	COG2986	histidine ammonia-lyase
L2Z27_RS07865	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS07870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
L2Z27_RS07890	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
L2Z27_RS07900	COG1162	GTPase activity
L2Z27_RS07905	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
L2Z27_RS07920	COG1538	Outer membrane efflux protein
L2Z27_RS07925	COG0577	efflux transmembrane transporter activity
L2Z27_RS07925	COG1136	(ABC) transporter
L2Z27_RS07930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS07955	COG0028	Belongs to the TPP enzyme family
L2Z27_RS07960	COG0440	acetolactate synthase activity
L2Z27_RS07990	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
L2Z27_RS08005	COG0084	hydrolase, TatD family'
L2Z27_RS08020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
L2Z27_RS08030	COG0583	DNA-binding transcription factor activity
L2Z27_RS08040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z27_RS08045	COG2814	Major facilitator Superfamily
L2Z27_RS08055	COG0697	spore germination
L2Z27_RS08085	COG3622	Belongs to the hyi family
L2Z27_RS08090	COG2084	Dehydrogenase
L2Z27_RS08095	COG1024	Enoyl-CoA hydratase
L2Z27_RS08100	COG0784	Response regulator, receiver
L2Z27_RS08100	COG2205	protein histidine kinase activity
L2Z27_RS08100	COG5002	protein histidine kinase activity
L2Z27_RS08120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
L2Z27_RS08130	COG3956	TIGRFAM MazG family protein
L2Z27_RS08135	COG1555	photosystem II stabilization
L2Z27_RS08140	COG0617	tRNA 3'-terminal CCA addition
L2Z27_RS08145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
L2Z27_RS08165	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z27_RS08170	COG3028	Belongs to the UPF0307 family
L2Z27_RS08175	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z27_RS08190	COG0625	glutathione transferase activity
L2Z27_RS08195	COG1238	metal cluster binding
L2Z27_RS08240	COG0072	phenylalanine-tRNA ligase activity
L2Z27_RS08270	COG0248	Ppx GppA phosphatase
L2Z27_RS08280	COG0037	tRNA processing
L2Z27_RS08330	COG1764	response to oxidative stress
L2Z27_RS08335	COG1846	Transcriptional regulator
L2Z27_RS08345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z27_RS08405	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
L2Z27_RS08410	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
L2Z27_RS08415	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
L2Z27_RS08475	COG1214	PFAM Peptidase M22, glycoprotease
L2Z27_RS08500	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
L2Z27_RS08505	COG0561	phosphatase activity
L2Z27_RS08515	COG2132	Multicopper oxidase
L2Z27_RS08520	COG3667	copper resistance
L2Z27_RS08535	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
L2Z27_RS08540	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
L2Z27_RS08545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
L2Z27_RS08575	COG1063	alcohol dehydrogenase
L2Z27_RS08580	COG0583	DNA-binding transcription factor activity
L2Z27_RS08585	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS08590	COG2814	Major facilitator Superfamily
L2Z27_RS08595	COG1804	L-carnitine dehydratase bile acid-inducible protein F
L2Z27_RS08605	COG1053	succinate dehydrogenase
L2Z27_RS08610	COG0583	DNA-binding transcription factor activity
L2Z27_RS08625	COG0583	DNA-binding transcription factor activity
L2Z27_RS08655	COG0583	DNA-binding transcription factor activity
L2Z27_RS08670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z27_RS08695	COG0384	phenazine biosynthesis protein PhzF
L2Z27_RS08720	COG4993	Dehydrogenase
L2Z27_RS08785	COG2205	protein histidine kinase activity
L2Z27_RS08795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
L2Z27_RS08815	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS08855	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
L2Z27_RS08885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
L2Z27_RS08890	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
L2Z27_RS08910	COG0583	DNA-binding transcription factor activity
L2Z27_RS08930	COG0668	transmembrane transport
L2Z27_RS08940	COG2081	HI0933 family
L2Z27_RS08945	COG2515	1-aminocyclopropane-1-carboxylate deaminase
L2Z27_RS08975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z27_RS08975	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
L2Z27_RS08985	COG0489	protein tyrosine kinase activity
L2Z27_RS09035	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
L2Z27_RS09045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
L2Z27_RS09060	COG0730	response to heat
L2Z27_RS09070	COG1196	nuclear chromosome segregation
L2Z27_RS09090	COG2223	nitrite transmembrane transporter activity
L2Z27_RS09095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
L2Z27_RS09100	COG1877	trehalose-phosphatase activity
L2Z27_RS09105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z27_RS09105	COG2226	methyltransferase
L2Z27_RS09105	COG0596	Alpha beta hydrolase
L2Z27_RS09120	COG4106	trans-aconitate 2-methyltransferase activity
L2Z27_RS09135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
L2Z27_RS09140	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
L2Z27_RS09145	COG0009	L-threonylcarbamoyladenylate synthase
L2Z27_RS09150	COG3101	peptidyl-lysine hydroxylation
L2Z27_RS09155	COG1399	metal-binding, possibly nucleic acid-binding protein
L2Z27_RS09185	COG1652	LysM domain
L2Z27_RS09190	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
L2Z27_RS09190	COG0352	thiamine-phosphate diphosphorylase activity
L2Z27_RS09190	COG0351	phosphomethylpyrimidine kinase
L2Z27_RS09200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
L2Z27_RS09230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z27_RS09260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
L2Z27_RS09275	COG0358	DNA primase activity
L2Z27_RS09285	COG0564	pseudouridine synthase activity
L2Z27_RS09310	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z27_RS09330	COG0583	DNA-binding transcription factor activity
L2Z27_RS09335	COG0473	3-isopropylmalate dehydrogenase activity
L2Z27_RS09345	COG0657	acetylesterase activity
L2Z27_RS09355	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
L2Z27_RS09375	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
L2Z27_RS09390	COG1981	membrane
L2Z27_RS09435	COG0456	acetyltransferase
L2Z27_RS09445	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
L2Z27_RS09450	COG0492	ferredoxin-NADP+ reductase activity
L2Z27_RS09455	COG1674	ftsk spoiiie
L2Z27_RS09455	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
L2Z27_RS09460	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS09485	COG2894	cell division
L2Z27_RS09500	COG0204	Acyl-transferase
L2Z27_RS09505	COG2885	chlorophyll binding
L2Z27_RS09510	COG0210	DNA helicase
L2Z27_RS09520	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
L2Z27_RS09535	COG0121	glutamine amidotransferase
L2Z27_RS09555	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
L2Z27_RS09560	COG0735	belongs to the Fur family
L2Z27_RS09585	COG0420	3'-5' exonuclease activity
L2Z27_RS09605	COG1090	epimerase
L2Z27_RS09620	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z27_RS09630	COG2814	Major facilitator Superfamily
L2Z27_RS09635	COG0405	Gamma-glutamyltransferase
L2Z27_RS09705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z27_RS09795	COG1484	DNA-dependent DNA replication
L2Z27_RS09990	COG2026	Addiction module toxin, RelE StbE family
L2Z27_RS10030	COG0592	DNA-directed DNA polymerase activity
L2Z27_RS10135	COG0582	viral genome integration into host DNA
L2Z27_RS10190	COG0629	single-stranded DNA binding
L2Z27_RS10210	COG2826	transposase and inactivated derivatives, IS30 family
L2Z27_RS10235	COG0084	hydrolase, TatD family'
L2Z27_RS10255	COG0477	Major facilitator Superfamily
L2Z27_RS10260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z27_RS10270	COG1595	DNA-templated transcription, initiation
L2Z27_RS10335	COG0531	amino acid
L2Z27_RS10340	COG2040	homocysteine
L2Z27_RS10365	COG1309	transcriptional regulator
L2Z27_RS10370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z27_RS10375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z27_RS10385	COG1607	acyl-coa hydrolase
L2Z27_RS10395	COG0523	cobalamin synthesis protein
L2Z27_RS10405	COG4681	YaeQ
L2Z27_RS10415	COG0726	polysaccharide deacetylase
L2Z27_RS10415	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z27_RS10420	COG1215	transferase activity, transferring glycosyl groups
L2Z27_RS10430	COG1024	Enoyl-CoA hydratase
L2Z27_RS10445	COG1414	Transcriptional regulator
L2Z27_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS10475	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z27_RS10480	COG2271	Major facilitator Superfamily
L2Z27_RS10490	COG2267	carboxylic ester hydrolase activity
L2Z27_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS10510	COG0028	Belongs to the TPP enzyme family
L2Z27_RS10520	COG0477	Major facilitator Superfamily
L2Z27_RS10525	COG0242	peptide deformylase activity
L2Z27_RS10530	COG2066	Belongs to the glutaminase family
L2Z27_RS10535	COG2207	Transcriptional regulator
L2Z27_RS10540	COG2223	nitrite transmembrane transporter activity
L2Z27_RS10555	COG0583	DNA-binding transcription factor activity
L2Z27_RS10560	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS10565	COG2271	Major facilitator Superfamily
L2Z27_RS10570	COG3959	Transketolase, thiamine diphosphate binding domain
L2Z27_RS10575	COG3958	Transketolase
L2Z27_RS10585	COG0306	phosphate transporter
L2Z27_RS10605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
L2Z27_RS10650	COG4181	ATPase activity
L2Z27_RS10655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
L2Z27_RS10680	COG0583	DNA-binding transcription factor activity
L2Z27_RS10690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z27_RS10695	COG1773	rubredoxin
L2Z27_RS10750	COG2851	Citrate transporter
L2Z27_RS10755	COG1253	flavin adenine dinucleotide binding
L2Z27_RS10795	COG0804	urea catabolic process
L2Z27_RS10805	COG0830	nickel cation binding
L2Z27_RS10820	COG0742	ribosomal rna small subunit methyltransferase
L2Z27_RS10825	COG0768	penicillin binding
L2Z27_RS10850	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
L2Z27_RS10855	COG2878	Part of a membrane complex involved in electron transport
L2Z27_RS10860	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
L2Z27_RS10870	COG3384	dioxygenase
L2Z27_RS10895	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
L2Z27_RS11220	COG0739	heme binding
L2Z27_RS11265	COG2194	sulfuric ester hydrolase activity
L2Z27_RS11305	COG0006	proline dipeptidase activity
L2Z27_RS11310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z27_RS11315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z27_RS11335	COG1279	arginine transmembrane transporter activity
L2Z27_RS11340	COG0583	DNA-binding transcription factor activity
L2Z27_RS11380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z27_RS11385	COG1388	LysM domain
L2Z27_RS11385	COG0741	lytic transglycosylase activity
L2Z27_RS11385	COG1388	LysM domain
L2Z27_RS11385	COG0741	lytic transglycosylase activity
L2Z27_RS11395	COG4174	ABC transporter (Permease)
L2Z27_RS11400	COG4239	(ABC) transporter, permease
L2Z27_RS11405	COG4172	Belongs to the ABC transporter superfamily
L2Z27_RS11425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
L2Z27_RS11435	COG4251	negative regulation of phosphorylation
L2Z27_RS11435	COG2203	Gaf domain
L2Z27_RS11435	COG5001	Diguanylate cyclase
L2Z27_RS11435	COG3706	GGDEF domain
L2Z27_RS11445	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z27_RS11445	COG1902	pentaerythritol trinitrate reductase activity
L2Z27_RS11485	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
L2Z27_RS11515	COG2072	flavoprotein involved in K transport
L2Z27_RS11530	COG1741	Belongs to the pirin family
L2Z27_RS11535	COG1309	transcriptional regulator
L2Z27_RS11550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
L2Z27_RS11555	COG3038	cytochrome b561
L2Z27_RS11565	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
L2Z27_RS11575	COG0527	aspartate kinase activity
L2Z27_RS11585	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
L2Z27_RS11595	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
L2Z27_RS11610	COG0667	Aldo Keto reductase
L2Z27_RS11630	COG1765	OsmC-like protein
L2Z27_RS11645	COG0542	response to heat
L2Z27_RS11680	COG2885	chlorophyll binding
L2Z27_RS11690	COG0625	glutathione transferase activity
L2Z27_RS11695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
L2Z27_RS11715	COG3634	alkyl hydroperoxide reductase activity
L2Z27_RS11725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
L2Z27_RS11735	COG0450	alkyl hydroperoxide reductase
L2Z27_RS11740	COG1643	Atp-dependent helicase
L2Z27_RS11755	COG2814	Major facilitator Superfamily
L2Z27_RS11760	COG3135	benzoate transporter
L2Z27_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS11770	COG0633	Ferredoxin
L2Z27_RS11770	COG0543	2 iron, 2 sulfur cluster binding
L2Z27_RS11775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z27_RS11780	COG4638	Rieske (2fe-2S)
L2Z27_RS11790	COG0583	DNA-binding transcription factor activity
L2Z27_RS11840	COG1570	exodeoxyribonuclease VII activity
L2Z27_RS11870	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS11875	COG1278	Cold shock
L2Z27_RS11910	COG2814	Major facilitator Superfamily
L2Z27_RS11945	COG0517	IMP dehydrogenase activity
L2Z27_RS11945	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
L2Z27_RS11950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
L2Z27_RS11960	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
L2Z27_RS11965	COG1137	ATPase activity
L2Z27_RS11970	COG1538	Outer membrane efflux protein
L2Z27_RS12000	COG4122	O-methyltransferase activity
L2Z27_RS12010	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
L2Z27_RS12025	COG1522	sequence-specific DNA binding
L2Z27_RS12030	COG5006	permease, DMT superfamily
L2Z27_RS12040	COG1560	Kdo2-lipid A biosynthetic process
L2Z27_RS12055	COG2814	Major facilitator Superfamily
L2Z27_RS12075	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z27_RS12125	COG0583	DNA-binding transcription factor activity
L2Z27_RS12130	COG1914	H( )-stimulated, divalent metal cation uptake system
L2Z27_RS12150	COG4770	biotin carboxylase activity
L2Z27_RS12155	COG0038	chloride channel
L2Z27_RS12175	COG1309	transcriptional regulator
L2Z27_RS12200	COG0439	Biotin carboxylase
L2Z27_RS12205	COG2249	NAD(P)H dehydrogenase (quinone) activity
L2Z27_RS12225	COG0864	Transcriptional regulator
L2Z27_RS12235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z27_RS12240	COG1116	anion transmembrane transporter activity
L2Z27_RS12360	COG0590	tRNA wobble adenosine to inosine editing
L2Z27_RS12365	COG2807	transmembrane transport
L2Z27_RS12380	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
L2Z27_RS12395	COG0789	Transcriptional regulator
L2Z27_RS12405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
L2Z27_RS12425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z27_RS12435	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z27_RS12450	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS12455	COG0531	amino acid
L2Z27_RS12460	COG1760	l-serine dehydratase
L2Z27_RS12465	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS12465	COG2030	dehydratase
L2Z27_RS12470	COG3396	Phenylacetate-CoA oxygenase
L2Z27_RS12475	COG3460	Phenylacetate-CoA oxygenase
L2Z27_RS12480	COG3396	Phenylacetate-CoA oxygenase
L2Z27_RS12485	COG2151	metal-sulfur cluster biosynthetic enzyme
L2Z27_RS12490	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z27_RS12495	COG1024	Enoyl-CoA hydratase
L2Z27_RS12500	COG1024	Enoyl-CoA hydratase
L2Z27_RS12505	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z27_RS12510	COG0183	Belongs to the thiolase family
L2Z27_RS12515	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
L2Z27_RS12520	COG3327	negative regulation of DNA-templated transcription, initiation
L2Z27_RS12530	COG2050	protein possibly involved in aromatic compounds catabolism
L2Z27_RS12560	COG0753	catalase activity
L2Z27_RS12565	COG3038	cytochrome b561
L2Z27_RS12585	COG2267	carboxylic ester hydrolase activity
L2Z27_RS12590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z27_RS12595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z27_RS12600	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS12610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z27_RS12620	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS12625	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z27_RS12630	COG0583	DNA-binding transcription factor activity
L2Z27_RS12640	COG1414	Transcriptional regulator
L2Z27_RS12645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
L2Z27_RS12655	COG1840	ABC-type Fe3 transport system, periplasmic component
L2Z27_RS12660	COG3842	ATPase activity
L2Z27_RS12675	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
L2Z27_RS12680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z27_RS12685	COG2814	Major facilitator Superfamily
L2Z27_RS12690	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS12705	COG1024	Enoyl-CoA hydratase
L2Z27_RS12715	COG2814	Major facilitator Superfamily
L2Z27_RS12725	COG0183	Belongs to the thiolase family
L2Z27_RS12730	COG1250	3-hydroxyacyl-CoA dehydrogenase
L2Z27_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS12740	COG1024	Enoyl-CoA hydratase
L2Z27_RS12745	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS12750	COG2814	Major facilitator Superfamily
L2Z27_RS12755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z27_RS12760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z27_RS12770	COG2814	Major facilitator Superfamily
L2Z27_RS12780	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS12795	COG0583	DNA-binding transcription factor activity
L2Z27_RS12805	COG4770	biotin carboxylase activity
L2Z27_RS12810	COG1024	Enoyl-CoA hydratase
L2Z27_RS12815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
L2Z27_RS12820	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS12825	COG1309	transcriptional regulator
L2Z27_RS12830	COG0318	PFAM AMP-dependent synthetase and ligase
L2Z27_RS12850	COG0583	DNA-binding transcription factor activity
L2Z27_RS12900	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS12920	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
L2Z27_RS12940	COG2205	protein histidine kinase activity
L2Z27_RS12940	COG0784	Response regulator, receiver
L2Z27_RS12960	COG0765	amino acid transport
L2Z27_RS12965	COG0765	amino acid transport
L2Z27_RS12970	COG1126	abc transporter atp-binding protein
L2Z27_RS12975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z27_RS12980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
L2Z27_RS12995	COG1280	lysine exporter protein (LysE YggA)
L2Z27_RS13005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
L2Z27_RS13010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z27_RS13015	COG1045	serine acetyltransferase
L2Z27_RS13030	COG0583	DNA-binding transcription factor activity
L2Z27_RS13035	COG0625	glutathione transferase activity
L2Z27_RS13040	COG0625	glutathione transferase activity
L2Z27_RS13045	COG0583	DNA-binding transcription factor activity
L2Z27_RS13055	COG1346	cytolysis
L2Z27_RS13075	COG2814	Major facilitator Superfamily
L2Z27_RS13085	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
L2Z27_RS13090	COG3052	prosthetic group binding
L2Z27_RS13110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
L2Z27_RS13130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z27_RS13140	COG1294	oxidase, subunit
L2Z27_RS13145	COG1271	oxidase subunit
L2Z27_RS13165	COG0477	Major facilitator Superfamily
L2Z27_RS13175	COG4521	taurine ABC transporter
L2Z27_RS13180	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
L2Z27_RS13185	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z27_RS13190	COG2175	clavaminate synthase activity
L2Z27_RS13200	COG1953	Uracil, thiamine, allantoin
L2Z27_RS13210	COG0583	DNA-binding transcription factor activity
L2Z27_RS13220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
L2Z27_RS13235	COG0640	Transcriptional regulator
L2Z27_RS13240	COG0798	PFAM Bile acid sodium symporter
L2Z27_RS13245	COG0583	DNA-binding transcription factor activity
L2Z27_RS13260	COG3634	alkyl hydroperoxide reductase activity
L2Z27_RS13300	COG0436	Aminotransferase
L2Z27_RS13310	COG0386	Belongs to the glutathione peroxidase family
L2Z27_RS13350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
L2Z27_RS13375	COG0012	GTP binding
L2Z27_RS13380	COG2011	ABC-type metal ion transport system permease component
L2Z27_RS13385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z27_RS13395	COG1464	Belongs to the NlpA lipoprotein family
L2Z27_RS13425	COG0765	amino acid transport
L2Z27_RS13430	COG0765	amino acid transport
L2Z27_RS13435	COG1126	abc transporter atp-binding protein
L2Z27_RS13445	COG1522	sequence-specific DNA binding
L2Z27_RS13460	COG1309	transcriptional regulator
L2Z27_RS13480	COG0583	DNA-binding transcription factor activity
L2Z27_RS13490	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
L2Z27_RS13500	COG0697	spore germination
L2Z27_RS13525	COG3121	Chaperone
L2Z27_RS13530	COG3539	Fimbrial protein
L2Z27_RS13555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
L2Z27_RS13555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
L2Z27_RS13600	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
L2Z27_RS13610	COG2353	YceI-like domain
L2Z27_RS13620	COG3698	Phosphodiester glycosidase
L2Z27_RS13635	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
L2Z27_RS13640	COG0506	proline dehydrogenase activity
L2Z27_RS13640	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z27_RS13640	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
L2Z27_RS13650	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
L2Z27_RS13655	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
L2Z27_RS13675	COG1132	(ABC) transporter
L2Z27_RS13680	COG3122	Protein conserved in bacteria
L2Z27_RS13685	COG3619	membrane
L2Z27_RS13695	COG0640	Transcriptional regulator
L2Z27_RS13705	COG2850	peptidyl-arginine hydroxylation
L2Z27_RS13710	COG0424	maF-like protein
L2Z27_RS13730	COG0191	fructose-bisphosphate aldolase activity
L2Z27_RS13735	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z27_RS13750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
L2Z27_RS13760	COG1192	Involved in chromosome partitioning
L2Z27_RS13765	COG1475	DNA binding
L2Z27_RS13770	COG0811	peptide transport
L2Z27_RS13780	COG1132	(ABC) transporter
L2Z27_RS13785	COG1663	tetraacyldisaccharide 4'-kinase activity
L2Z27_RS13805	COG0084	hydrolase, TatD family'
L2Z27_RS13870	COG0776	regulation of translation
L2Z27_RS13900	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
L2Z27_RS13905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
L2Z27_RS13975	COG0339	signal peptide processing
L2Z27_RS13985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
L2Z27_RS14020	COG0702	epimerase
L2Z27_RS14025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z27_RS14045	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
L2Z27_RS14075	COG0316	Belongs to the HesB IscA family
L2Z27_RS14080	COG0822	iron-sulfur transferase activity
L2Z27_RS14105	COG0776	regulation of translation
L2Z27_RS14110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
L2Z27_RS14115	COG2207	Transcriptional regulator
L2Z27_RS14120	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z27_RS14125	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS14130	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS14145	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
L2Z27_RS14165	COG4264	IucA IucC family
L2Z27_RS14170	COG4264	IucA IucC family
L2Z27_RS14210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
L2Z27_RS14225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
L2Z27_RS14245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
L2Z27_RS14250	COG0730	response to heat
L2Z27_RS14270	COG4773	Receptor
L2Z27_RS14275	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z27_RS14290	COG1131	(ABC) transporter
L2Z27_RS14295	COG0842	Transport permease protein
L2Z27_RS14300	COG0842	Transport permease protein
L2Z27_RS14355	COG2226	methyltransferase
L2Z27_RS14380	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
L2Z27_RS14415	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
L2Z27_RS14425	COG0133	tryptophan synthase activity
L2Z27_RS14440	COG3706	GGDEF domain
L2Z27_RS14455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z27_RS14460	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
L2Z27_RS14465	COG0022	dehydrogenase e1 component
L2Z27_RS14470	COG0508	dehydrogenase complex catalyzes the overall conversion of
L2Z27_RS14475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z27_RS14485	COG1063	alcohol dehydrogenase
L2Z27_RS14490	COG3781	membrane
L2Z27_RS14500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z27_RS14500	COG3453	Protein conserved in bacteria
L2Z27_RS14515	COG0730	response to heat
L2Z27_RS14530	COG2207	Transcriptional regulator
L2Z27_RS14530	COG3708	Transcriptional regulator
L2Z27_RS14535	COG1733	regulation of RNA biosynthetic process
L2Z27_RS14540	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
L2Z27_RS14550	COG2188	Transcriptional regulator
L2Z27_RS14565	COG4521	taurine ABC transporter
L2Z27_RS14570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z27_RS14590	COG0477	Major facilitator Superfamily
L2Z27_RS14600	COG1027	Aspartate ammonia-lyase
L2Z27_RS14615	COG0583	DNA-binding transcription factor activity
L2Z27_RS14620	COG0583	DNA-binding transcription factor activity
L2Z27_RS14625	COG0183	Belongs to the thiolase family
L2Z27_RS14630	COG2031	fatty acid transporter
L2Z27_RS14635	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z27_RS14645	COG0583	DNA-binding transcription factor activity
L2Z27_RS14655	COG2610	gluconate transmembrane transporter activity
L2Z27_RS14660	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS14670	COG2207	Transcriptional regulator
L2Z27_RS14685	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS14710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
L2Z27_RS14710	COG0543	2 iron, 2 sulfur cluster binding
L2Z27_RS14715	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
L2Z27_RS14720	COG4638	Rieske (2fe-2S)
L2Z27_RS14730	COG0725	ABC transporter, periplasmic molybdate-binding protein
L2Z27_RS14735	COG4149	molybdate abc transporter
L2Z27_RS14740	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
L2Z27_RS14745	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS14750	COG1535	isochorismatase
L2Z27_RS14750	COG3433	isochorismatase activity
L2Z27_RS14810	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
L2Z27_RS14825	COG0753	catalase activity
L2Z27_RS14835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
L2Z27_RS14865	COG3539	Fimbrial protein
L2Z27_RS14885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
L2Z27_RS14905	COG2072	flavoprotein involved in K transport
L2Z27_RS14915	COG1538	Outer membrane efflux protein
L2Z27_RS14920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
L2Z27_RS14925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS14930	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS14935	COG2205	protein histidine kinase activity
L2Z27_RS14945	COG2207	Transcriptional regulator
L2Z27_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS15010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
L2Z27_RS15130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
L2Z27_RS15150	COG1120	ATPase activity
L2Z27_RS15155	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z27_RS15165	COG1064	alcohol dehydrogenase
L2Z27_RS15180	COG2207	Transcriptional regulator
L2Z27_RS15185	COG2084	Dehydrogenase
L2Z27_RS15195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
L2Z27_RS15200	COG0583	DNA-binding transcription factor activity
L2Z27_RS15210	COG0129	dihydroxy-acid dehydratase activity
L2Z27_RS15215	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS15230	COG1566	PFAM secretion protein HlyD family protein
L2Z27_RS15260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
L2Z27_RS15290	COG0583	DNA-binding transcription factor activity
L2Z27_RS15305	COG2188	Transcriptional regulator
L2Z27_RS15335	COG3210	domain, Protein
L2Z27_RS15340	COG2831	hemolysin activation secretion protein
L2Z27_RS15350	COG1473	amidohydrolase
L2Z27_RS15360	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
L2Z27_RS15360	COG0475	glutathione-regulated potassium exporter activity
L2Z27_RS15370	COG0583	DNA-binding transcription factor activity
L2Z27_RS15375	COG1335	isochorismatase
L2Z27_RS15385	COG1309	transcriptional regulator
L2Z27_RS15415	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
L2Z27_RS15425	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z27_RS15425	COG1902	pentaerythritol trinitrate reductase activity
L2Z27_RS15430	COG1846	Transcriptional regulator
L2Z27_RS15450	COG0753	catalase activity
L2Z27_RS15465	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS15480	COG3162	membrane
L2Z27_RS15490	COG3829	transcription factor binding
L2Z27_RS15495	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS15500	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS15520	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS15540	COG2186	Transcriptional regulator
L2Z27_RS15550	COG0583	DNA-binding transcription factor activity
L2Z27_RS15555	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z27_RS15560	COG4829	muconolactone delta-isomerase
L2Z27_RS15570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z27_RS15575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z27_RS15580	COG0183	Belongs to the thiolase family
L2Z27_RS15585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
L2Z27_RS15595	COG1012	belongs to the aldehyde dehydrogenase family
L2Z27_RS15605	COG3733	amine oxidase
L2Z27_RS15615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z27_RS15625	COG1028	Short-chain dehydrogenase reductase Sdr
L2Z27_RS15635	COG4638	Rieske (2fe-2S)
L2Z27_RS15655	COG0154	amidase activity
L2Z27_RS15665	COG2814	Major facilitator Superfamily
L2Z27_RS15690	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS15695	COG0583	DNA-binding transcription factor activity
L2Z27_RS15700	COG1414	Transcriptional regulator
L2Z27_RS15715	COG2391	methyltransferase activity
L2Z27_RS15725	COG4993	Dehydrogenase
L2Z27_RS15730	COG3659	wide pore channel activity
L2Z27_RS15735	COG3420	alginic acid biosynthetic process
L2Z27_RS15740	COG0710	3-dehydroquinate dehydratase activity
L2Z27_RS15745	COG3485	protocatechuate 3,4-dioxygenase
L2Z27_RS15750	COG3485	protocatechuate 3,4-dioxygenase
L2Z27_RS15755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
L2Z27_RS15760	COG2271	Major facilitator Superfamily
L2Z27_RS15765	COG0596	Alpha beta hydrolase
L2Z27_RS15770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
L2Z27_RS15775	COG0183	Belongs to the thiolase family
L2Z27_RS15780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
L2Z27_RS15785	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
L2Z27_RS15795	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
L2Z27_RS15800	COG2323	membrane
L2Z27_RS15845	COG0446	pyridine nucleotide-disulphide oxidoreductase
L2Z27_RS15845	COG1902	pentaerythritol trinitrate reductase activity
L2Z27_RS15870	COG0542	response to heat
L2Z27_RS15875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
L2Z27_RS15905	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
L2Z27_RS15910	COG0569	domain protein
L2Z27_RS15915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
L2Z27_RS15930	COG4774	siderophore transport
L2Z27_RS15935	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
L2Z27_RS15945	COG1585	Membrane protein implicated in regulation of membrane protease activity
L2Z27_RS15965	COG1294	oxidase, subunit
L2Z27_RS15970	COG4890	Cyd operon protein YbgT
L2Z27_RS15985	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
L2Z27_RS15995	COG0552	protein localization to endoplasmic reticulum
L2Z27_RS16020	COG0517	IMP dehydrogenase activity
L2Z27_RS16020	COG0516	GMP reductase activity
L2Z27_RS16025	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
L2Z27_RS16030	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
L2Z27_RS16040	COG0583	DNA-binding transcription factor activity
L2Z27_RS16045	COG0024	Methionine aminopeptidase
L2Z27_RS16075	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
L2Z27_RS16075	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
L2Z27_RS16080	COG1105	Belongs to the carbohydrate kinase PfkB family
L2Z27_RS16085	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z27_RS16085	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
L2Z27_RS16085	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
L2Z27_RS16105	COG3300	MHYT domain
L2Z27_RS16105	COG5001	Diguanylate cyclase
L2Z27_RS16120	COG2135	peptidase activity
L2Z27_RS16125	COG0659	secondary active sulfate transmembrane transporter activity
L2Z27_RS16145	COG1113	amino acid transport
L2Z27_RS16155	COG1522	sequence-specific DNA binding
L2Z27_RS16180	COG1011	Hydrolase
L2Z27_RS16185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
L2Z27_RS16195	COG2137	regulation of response to DNA damage stimulus
L2Z27_RS16210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z27_RS16245	COG0575	Belongs to the CDS family
L2Z27_RS16250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
L2Z27_RS16270	COG3852	Histidine kinase
L2Z27_RS16275	COG2204	response regulator
L2Z27_RS16330	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
L2Z27_RS16335	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
L2Z27_RS16355	COG0697	spore germination
L2Z27_RS16360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z27_RS16370	COG0303	'Molybdopterin
L2Z27_RS16375	COG0521	Mo-molybdopterin cofactor biosynthetic process
L2Z27_RS16375	COG0315	cyclic pyranopterin monophosphate synthase activity
L2Z27_RS16390	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
L2Z27_RS16395	COG0243	molybdopterin cofactor binding
L2Z27_RS16405	COG0243	molybdopterin cofactor binding
L2Z27_RS16410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z27_RS16415	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z27_RS16415	COG2146	nitrite reductase [NAD(P)H] activity
L2Z27_RS16425	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS16430	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z27_RS16430	COG1116	anion transmembrane transporter activity
L2Z27_RS16450	COG0511	ligase activity, forming carbon-carbon bonds
L2Z27_RS16465	COG2814	Major facilitator Superfamily
L2Z27_RS16530	COG0739	heme binding
L2Z27_RS16650	COG5410	chromosome segregation
L2Z27_RS16815	COG0069	glutamate synthase activity
L2Z27_RS16835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
L2Z27_RS16845	COG1454	alcohol dehydrogenase
L2Z27_RS16850	COG0824	Thioesterase
L2Z27_RS16860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
L2Z27_RS16875	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
L2Z27_RS16880	COG2030	dehydratase
L2Z27_RS16890	COG0183	Belongs to the thiolase family
L2Z27_RS16900	COG0583	DNA-binding transcription factor activity
L2Z27_RS16905	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
L2Z27_RS16915	COG1522	sequence-specific DNA binding
L2Z27_RS16920	COG3135	benzoate transporter
L2Z27_RS16930	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
L2Z27_RS16955	COG0589	response to stress
L2Z27_RS16960	COG0488	(ABC) transporter
L2Z27_RS16980	COG4773	Receptor
L2Z27_RS17015	COG0668	transmembrane transport
L2Z27_RS17025	COG1309	transcriptional regulator
L2Z27_RS17045	COG1605	Chorismate mutase
L2Z27_RS17075	COG0308	aminopeptidase N
L2Z27_RS17095	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
L2Z27_RS17105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
L2Z27_RS17110	COG1454	alcohol dehydrogenase
L2Z27_RS17130	COG0531	amino acid
L2Z27_RS17135	COG4303	Ethanolamine ammonia lyase large subunit
L2Z27_RS17140	COG4302	ethanolamine ammonia-lyase activity
L2Z27_RS17145	COG0519	Catalyzes the synthesis of GMP from XMP
L2Z27_RS17145	COG0518	GMP synthase (glutamine-hydrolyzing) activity
L2Z27_RS17150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
L2Z27_RS17160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
L2Z27_RS17175	COG0697	spore germination
L2Z27_RS17180	COG1923	regulation of RNA biosynthetic process
L2Z27_RS17190	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
L2Z27_RS17195	COG0802	atpase or kinase
L2Z27_RS17215	COG1187	pseudouridine synthase activity
L2Z27_RS17230	COG0583	DNA-binding transcription factor activity
L2Z27_RS17245	COG2814	Major facilitator Superfamily
L2Z27_RS17250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
L2Z27_RS17275	COG0729	surface antigen
L2Z27_RS17295	COG0174	glutamine synthetase
L2Z27_RS17300	COG0745	RESPONSE REGULATOR receiver
L2Z27_RS17305	COG2205	protein histidine kinase activity
L2Z27_RS17315	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
L2Z27_RS17320	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
L2Z27_RS17345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
L2Z27_RS17350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
L2Z27_RS17355	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS17370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
L2Z27_RS17375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
L2Z27_RS17395	COG0583	DNA-binding transcription factor activity
L2Z27_RS17410	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
L2Z27_RS17420	COG3658	cytochrome
L2Z27_RS17425	COG1215	transferase activity, transferring glycosyl groups
L2Z27_RS17430	COG0726	polysaccharide deacetylase
L2Z27_RS17430	COG1649	PFAM Uncharacterised BCR, COG1649
L2Z27_RS17455	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
L2Z27_RS17460	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
L2Z27_RS17470	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
L2Z27_RS17495	COG0305	Participates in initiation and elongation during chromosome replication
L2Z27_RS17500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
L2Z27_RS17510	COG1305	Transglutaminase-like
L2Z27_RS17520	COG2308	Evidence 4 Homologs of previously reported genes of
L2Z27_RS17550	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
L2Z27_RS17555	COG0138	bifunctional purine biosynthesis protein purh
L2Z27_RS17560	COG0151	Belongs to the GarS family
L2Z27_RS17565	COG1464	Belongs to the NlpA lipoprotein family
L2Z27_RS17570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
L2Z27_RS17575	COG2011	ABC-type metal ion transport system permease component
L2Z27_RS17580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
L2Z27_RS17590	COG1301	dicarboxylic acid transport
L2Z27_RS17610	COG0488	(ABC) transporter
L2Z27_RS17615	COG3173	Aminoglycoside phosphotransferase
L2Z27_RS17625	COG2433	Pfam Transposase IS66
L2Z27_RS17660	COG3243	poly(R)-hydroxyalkanoic acid synthase
L2Z27_RS17685	COG3111	PFAM Bacterial OB fold (BOF) protein
L2Z27_RS17785	COG1610	YqeY-like protein
L2Z27_RS17790	COG4783	chaperone-mediated protein folding
L2Z27_RS17815	COG1286	toxin biosynthetic process
L2Z27_RS17845	COG0778	Nitroreductase
L2Z27_RS17855	COG0513	Belongs to the DEAD box helicase family
L2Z27_RS17880	COG2363	Small membrane protein
L2Z27_RS17910	COG1234	tRNA 3'-trailer cleavage
L2Z27_RS17915	COG2195	Cleaves the N-terminal amino acid of tripeptides
L2Z27_RS17925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
L2Z27_RS17935	COG2819	hydrolase of the alpha beta superfamily
L2Z27_RS17940	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS17945	COG1301	dicarboxylic acid transport
L2Z27_RS17950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
L2Z27_RS17955	COG3139	Protein of unknown function (DUF1315)
L2Z27_RS17960	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
L2Z27_RS17965	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
L2Z27_RS17975	COG0494	nUDIX hydrolase
L2Z27_RS17985	COG0642	Histidine kinase
L2Z27_RS18000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
L2Z27_RS18010	COG1720	tRNA m6t6A37 methyltransferase activity
L2Z27_RS18025	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
L2Z27_RS18030	COG0826	peptidase U32
L2Z27_RS18035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
L2Z27_RS18045	COG4598	ABC transporter
L2Z27_RS18050	COG4160	amino acid transport
L2Z27_RS18055	COG4215	(ABC) transporter
L2Z27_RS18070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
L2Z27_RS18115	COG1131	(ABC) transporter
L2Z27_RS18120	COG0842	Transport permease protein
L2Z27_RS18135	COG0772	Belongs to the SEDS family
L2Z27_RS18140	COG2951	lytic endotransglycosylase activity
L2Z27_RS18165	COG2207	Transcriptional regulator
L2Z27_RS18180	COG0052	Belongs to the universal ribosomal protein uS2 family
L2Z27_RS18185	COG0024	Methionine aminopeptidase
L2Z27_RS18195	COG2223	nitrite transmembrane transporter activity
L2Z27_RS18205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
L2Z27_RS18210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
L2Z27_RS18215	COG1960	acyl-CoA dehydrogenase activity
L2Z27_RS18230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
L2Z27_RS18235	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
L2Z27_RS18240	COG1385	rRNA (uridine-N3-)-methyltransferase activity
L2Z27_RS18260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
L2Z27_RS18265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
L2Z27_RS18270	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
L2Z27_RS18305	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
L2Z27_RS18315	COG0174	glutamine synthetase
L2Z27_RS18330	COG0512	Glutamine amidotransferase of anthranilate synthase
L2Z27_RS18335	COG0308	aminopeptidase N
L2Z27_RS18365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
L2Z27_RS18375	COG0302	gtp cyclohydrolase
L2Z27_RS18400	COG3739	integral membrane protein
L2Z27_RS18415	COG1169	isochorismate synthase
L2Z27_RS18425	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
L2Z27_RS18430	COG1132	(ABC) transporter
L2Z27_RS18435	COG1132	(ABC) transporter
L2Z27_RS18450	COG1535	isochorismatase
L2Z27_RS18450	COG3433	isochorismatase activity
L2Z27_RS18455	COG1021	2,3-dihydroxybenzoate-AMP ligase
L2Z27_RS18460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z27_RS18470	COG4774	siderophore transport
L2Z27_RS18475	COG4607	ABC-type enterochelin transport system periplasmic component
L2Z27_RS18480	COG4604	ABC transporter, ATP-binding protein
L2Z27_RS18485	COG4605	iron ion homeostasis
L2Z27_RS18490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
L2Z27_RS18495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
L2Z27_RS18510	COG2964	Protein conserved in bacteria
L2Z27_RS18520	COG1741	Belongs to the pirin family
L2Z27_RS18540	COG1309	transcriptional regulator
L2Z27_RS18550	COG4948	Mandelate Racemase Muconate Lactonizing
L2Z27_RS18555	COG2814	Major facilitator Superfamily
L2Z27_RS18595	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
L2Z27_RS18615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
L2Z27_RS18625	COG0583	DNA-binding transcription factor activity
L2Z27_RS18630	COG1113	amino acid transport
L2Z27_RS18650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
L2Z27_RS18650	COG2508	Transcriptional regulator
L2Z27_RS18685	COG2879	small protein