locus-tag	class	description
CTY05_RS00010	COG0592	DNA-directed DNA polymerase activity
CTY05_RS00020	COG0187	DNA topoisomerase II activity
CTY05_RS00030	COG0586	Pfam SNARE associated Golgi protein
CTY05_RS00035	COG0488	(ABC) transporter
CTY05_RS00060	COG0596	Alpha beta hydrolase
CTY05_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTY05_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTY05_RS00110	COG0733	neurotransmitter:sodium symporter activity
CTY05_RS00145	COG0583	DNA-binding transcription factor activity
CTY05_RS00150	COG2233	PERMEase
CTY05_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS00200	COG2814	Major facilitator Superfamily
CTY05_RS00205	COG0656	L-ascorbic acid biosynthetic process
CTY05_RS00210	COG0583	DNA-binding transcription factor activity
CTY05_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTY05_RS00230	COG1064	alcohol dehydrogenase
CTY05_RS00235	COG2818	Glycosylase
CTY05_RS00250	COG1194	a g-specific adenine glycosylase
CTY05_RS00270	COG2983	Belongs to the UPF0260 family
CTY05_RS00275	COG2133	pyrroloquinoline quinone binding
CTY05_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTY05_RS00285	COG2116	formate transmembrane transporter activity
CTY05_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTY05_RS00310	COG1335	isochorismatase
CTY05_RS00315	COG0385	Bile acid
CTY05_RS00320	COG0534	Mate efflux family protein
CTY05_RS00325	COG1683	Conserved Protein
CTY05_RS00345	COG0625	glutathione transferase activity
CTY05_RS00355	COG1113	amino acid transport
CTY05_RS00365	COG0523	cobalamin synthesis protein
CTY05_RS00375	COG2188	Transcriptional regulator
CTY05_RS00405	COG0010	Belongs to the arginase family
CTY05_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTY05_RS00450	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTY05_RS00460	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTY05_RS00465	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTY05_RS00555	COG0534	Mate efflux family protein
CTY05_RS00560	COG0436	Aminotransferase
CTY05_RS00565	COG2733	membrane
CTY05_RS00580	COG2918	glutathione biosynthetic process
CTY05_RS00595	COG5632	N-Acetylmuramoyl-L-alanine amidase
CTY05_RS00595	COG3409	Peptidoglycan-binding domain 1 protein
CTY05_RS00595	COG1388	LysM domain
CTY05_RS00625	COG3150	esterase
CTY05_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTY05_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTY05_RS00655	COG2233	PERMEase
CTY05_RS00660	COG2351	hydroxyisourate hydrolase activity
CTY05_RS00695	COG3706	GGDEF domain
CTY05_RS00710	COG1393	Belongs to the ArsC family
CTY05_RS00715	COG0708	Exodeoxyribonuclease III
CTY05_RS00735	COG0189	ligase activity
CTY05_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTY05_RS00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTY05_RS00780	COG4942	peptidase
CTY05_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTY05_RS00800	COG2119	membrane
CTY05_RS00805	COG4774	siderophore transport
CTY05_RS00810	COG0426	domain, Protein
CTY05_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTY05_RS00855	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS00860	COG1519	Transferase
CTY05_RS00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTY05_RS00870	COG0668	transmembrane transport
CTY05_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTY05_RS00885	COG1335	isochorismatase
CTY05_RS00890	COG1522	sequence-specific DNA binding
CTY05_RS00915	COG2205	protein histidine kinase activity
CTY05_RS00915	COG2198	Histidine kinase
CTY05_RS00915	COG0784	Response regulator, receiver
CTY05_RS00920	COG3162	membrane
CTY05_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTY05_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTY05_RS00950	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTY05_RS00955	COG1309	transcriptional regulator
CTY05_RS00975	COG0351	phosphomethylpyrimidine kinase
CTY05_RS00975	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTY05_RS00975	COG0352	thiamine-phosphate diphosphorylase activity
CTY05_RS00985	COG2814	Major facilitator Superfamily
CTY05_RS01000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTY05_RS01010	COG1113	amino acid transport
CTY05_RS01020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTY05_RS01025	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS01035	COG1335	isochorismatase
CTY05_RS01100	COG1401	restriction endodeoxyribonuclease activity
CTY05_RS01140	COG1073	alpha beta
CTY05_RS01145	COG0583	DNA-binding transcription factor activity
CTY05_RS01160	COG1309	transcriptional regulator
CTY05_RS01250	COG2814	Major facilitator Superfamily
CTY05_RS01255	COG0583	DNA-binding transcription factor activity
CTY05_RS01275	COG0667	Aldo Keto reductase
CTY05_RS01300	COG1733	regulation of RNA biosynthetic process
CTY05_RS01315	COG1733	regulation of RNA biosynthetic process
CTY05_RS01325	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTY05_RS01335	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CTY05_RS01395	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTY05_RS01435	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTY05_RS01465	COG0427	acetyl-CoA hydrolase
CTY05_RS01490	COG0659	secondary active sulfate transmembrane transporter activity
CTY05_RS01495	COG4221	oxidoreductase activity
CTY05_RS01500	COG2873	o-acetylhomoserine
CTY05_RS01505	COG0488	(ABC) transporter
CTY05_RS01570	COG0833	amino acid
CTY05_RS01615	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTY05_RS01620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTY05_RS01635	COG2226	methyltransferase
CTY05_RS01685	COG0067	glutamate synthase
CTY05_RS01685	COG0070	glutamate synthase
CTY05_RS01685	COG0069	glutamate synthase activity
CTY05_RS01690	COG0493	'glutamate synthase
CTY05_RS01700	COG1704	LemA family
CTY05_RS01705	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTY05_RS01720	COG3307	-O-antigen
CTY05_RS01740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTY05_RS01755	COG0194	GDP metabolic process
CTY05_RS01805	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTY05_RS01825	COG5380	lipid catabolic process
CTY05_RS01830	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTY05_RS01855	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTY05_RS01860	COG0277	FAD linked oxidase domain protein
CTY05_RS01870	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTY05_RS01875	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTY05_RS01890	COG1289	transmembrane transporter activity
CTY05_RS01900	COG0628	permease
CTY05_RS01905	COG1192	Involved in chromosome partitioning
CTY05_RS01935	COG0833	amino acid
CTY05_RS01940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTY05_RS01945	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTY05_RS01955	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS01995	COG0583	DNA-binding transcription factor activity
CTY05_RS02045	COG0517	IMP dehydrogenase activity
CTY05_RS02050	COG1983	PspC domain protein
CTY05_RS02060	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02075	COG0408	coproporphyrinogen oxidase activity
CTY05_RS02095	COG0513	Belongs to the DEAD box helicase family
CTY05_RS02100	COG1127	ABC transporter
CTY05_RS02105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTY05_RS02115	COG2854	intermembrane phospholipid transfer
CTY05_RS02125	COG0598	Magnesium transport protein CorA
CTY05_RS02135	COG0494	nUDIX hydrolase
CTY05_RS02140	COG1040	competence protein
CTY05_RS02145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTY05_RS02165	COG1946	Acyl-CoA thioesterase
CTY05_RS02170	COG1301	dicarboxylic acid transport
CTY05_RS02185	COG1959	2 iron, 2 sulfur cluster binding
CTY05_RS02190	COG1017	nitric oxide dioxygenase activity
CTY05_RS02190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTY05_RS02195	COG0433	COG0433 Predicted ATPase
CTY05_RS02200	COG0626	cystathionine gamma-synthase activity
CTY05_RS02355	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02360	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTY05_RS02390	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTY05_RS02395	COG0339	signal peptide processing
CTY05_RS02400	COG0557	exoribonuclease II activity
CTY05_RS02445	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTY05_RS02450	COG2169	Transcriptional regulator
CTY05_RS02455	COG0697	spore germination
CTY05_RS02460	COG1295	ribonuclease BN
CTY05_RS02495	COG1702	phosphate starvation-inducible protein PhoH
CTY05_RS02505	COG1196	nuclear chromosome segregation
CTY05_RS02505	COG0741	lytic transglycosylase activity
CTY05_RS02505	COG0739	heme binding
CTY05_RS02535	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTY05_RS02540	COG1183	phosphatidylcholine synthase activity
CTY05_RS02585	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02590	COG1309	transcriptional regulator
CTY05_RS02605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTY05_RS02610	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02630	COG2969	positive regulation of protein catabolic process
CTY05_RS02640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTY05_RS02655	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTY05_RS02660	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTY05_RS02680	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTY05_RS02690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTY05_RS02695	COG1408	metallophosphoesterase
CTY05_RS02705	COG2199	diguanylate cyclase activity
CTY05_RS02765	COG1607	acyl-coa hydrolase
CTY05_RS02795	COG2350	Protein conserved in bacteria
CTY05_RS02805	COG0613	PHP domain protein
CTY05_RS02810	COG3781	membrane
CTY05_RS02820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTY05_RS02835	COG1862	Preprotein translocase
CTY05_RS02865	COG2205	protein histidine kinase activity
CTY05_RS02870	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTY05_RS02890	COG0726	polysaccharide deacetylase
CTY05_RS02895	COG0463	Glycosyl transferase, family 2
CTY05_RS02900	COG0438	transferase activity, transferring glycosyl groups
CTY05_RS02965	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02970	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS02980	COG2205	protein histidine kinase activity
CTY05_RS02985	COG0745	RESPONSE REGULATOR receiver
CTY05_RS02990	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTY05_RS03010	COG2096	Adenosyltransferase
CTY05_RS03060	COG0285	dihydrofolate synthase activity
CTY05_RS03080	COG0450	alkyl hydroperoxide reductase
CTY05_RS03095	COG0477	Major facilitator Superfamily
CTY05_RS03100	COG1272	protein, Hemolysin III
CTY05_RS03110	COG2153	protein acetylation
CTY05_RS03130	COG0183	Belongs to the thiolase family
CTY05_RS03135	COG2207	Transcriptional regulator
CTY05_RS03155	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTY05_RS03175	COG0183	Belongs to the thiolase family
CTY05_RS03185	COG2885	chlorophyll binding
CTY05_RS03185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTY05_RS03190	COG1690	Belongs to the RtcB family
CTY05_RS03195	COG0833	amino acid
CTY05_RS03205	COG2233	PERMEase
CTY05_RS03210	COG1217	gtp-binding protein TYPA
CTY05_RS03235	COG2094	Belongs to the DNA glycosylase MPG family
CTY05_RS03240	COG4772	TonB-dependent receptor
CTY05_RS03245	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS03260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTY05_RS03265	COG0354	folic acid binding
CTY05_RS03275	COG3189	MarR family transcriptional regulator
CTY05_RS03280	COG2824	Alkylphosphonate utilization operon protein PhnA
CTY05_RS03285	COG3422	double-strand break repair
CTY05_RS03325	COG0840	transmembrane signaling receptor activity
CTY05_RS03340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTY05_RS03355	COG5510	response to toxic substance
CTY05_RS03365	COG2832	Protein of unknown function (DUF454)
CTY05_RS03370	COG1376	ErfK ybiS ycfS ynhG family protein
CTY05_RS03410	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTY05_RS03420	COG1289	transmembrane transporter activity
CTY05_RS03425	COG2814	Major facilitator Superfamily
CTY05_RS03445	COG1115	amino acid carrier protein
CTY05_RS03450	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTY05_RS03455	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTY05_RS03460	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTY05_RS03485	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTY05_RS03495	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTY05_RS03500	COG1077	Cell shape determining protein MreB Mrl
CTY05_RS03505	COG1792	Involved in formation and maintenance of cell shape
CTY05_RS03510	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTY05_RS03515	COG0424	maF-like protein
CTY05_RS03520	COG1530	ribonuclease E activity
CTY05_RS03530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTY05_RS03540	COG0560	Phosphoserine phosphatase
CTY05_RS03550	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTY05_RS03575	COG2207	Transcriptional regulator
CTY05_RS03595	COG1113	amino acid transport
CTY05_RS03600	COG2828	Protein conserved in bacteria
CTY05_RS03605	COG0142	geranyltranstransferase activity
CTY05_RS03610	COG2315	Protein conserved in bacteria
CTY05_RS03625	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTY05_RS03645	COG2194	sulfuric ester hydrolase activity
CTY05_RS03650	COG0745	RESPONSE REGULATOR receiver
CTY05_RS03655	COG0642	Histidine kinase
CTY05_RS03665	COG0004	ammonium transporteR
CTY05_RS03675	COG0583	DNA-binding transcription factor activity
CTY05_RS03695	COG0525	valine-tRNA ligase activity
CTY05_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS03715	COG0393	Putative heavy-metal-binding
CTY05_RS03720	COG0393	Putative heavy-metal-binding
CTY05_RS03725	COG1538	Outer membrane efflux protein
CTY05_RS03735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS03740	COG0671	phosphoesterase, PA-phosphatase related
CTY05_RS03770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTY05_RS03785	COG1648	precorrin-2 dehydrogenase activity
CTY05_RS03785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTY05_RS03790	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTY05_RS03795	COG1733	regulation of RNA biosynthetic process
CTY05_RS03805	COG0531	amino acid
CTY05_RS03820	COG0321	lipoyl(octanoyl) transferase activity
CTY05_RS03825	COG2921	Belongs to the UPF0250 family
CTY05_RS03860	COG2009	succinate dehydrogenase
CTY05_RS03865	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTY05_RS03870	COG1053	succinate dehydrogenase
CTY05_RS03875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTY05_RS03900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTY05_RS03930	COG2354	Protein conserved in bacteria
CTY05_RS03935	COG2321	neutral zinc metallopeptidase
CTY05_RS03955	COG2843	Capsule synthesis protein
CTY05_RS03970	COG0589	response to stress
CTY05_RS03990	COG0505	Belongs to the CarA family
CTY05_RS04015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTY05_RS04020	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTY05_RS04070	COG0477	Major facilitator Superfamily
CTY05_RS04075	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTY05_RS04090	COG1597	lipid kinase activity
CTY05_RS04095	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTY05_RS04120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTY05_RS04125	COG0584	glycerophosphoryl diester phosphodiesterase
CTY05_RS04145	COG0741	lytic transglycosylase activity
CTY05_RS04170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTY05_RS04185	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTY05_RS04225	COG0778	Nitroreductase
CTY05_RS04240	COG1929	Belongs to the glycerate kinase type-1 family
CTY05_RS04245	COG0243	molybdopterin cofactor binding
CTY05_RS04250	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTY05_RS04255	COG3339	Conserved Protein
CTY05_RS04265	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTY05_RS04280	COG1113	amino acid transport
CTY05_RS04290	COG0019	diaminopimelate decarboxylase activity
CTY05_RS04300	COG2267	carboxylic ester hydrolase activity
CTY05_RS04305	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS04310	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTY05_RS04340	COG0463	Glycosyl transferase, family 2
CTY05_RS04360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS04390	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTY05_RS04395	COG1136	(ABC) transporter
CTY05_RS04400	COG0658	competence protein
CTY05_RS04400	COG2333	competence protein COMEC
CTY05_RS04410	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTY05_RS04410	COG0616	signal peptide processing
CTY05_RS04415	COG0596	Alpha beta hydrolase
CTY05_RS04420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTY05_RS04430	COG0628	permease
CTY05_RS04465	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTY05_RS04485	COG0823	Involved in the tonB-independent uptake of proteins
CTY05_RS04505	COG0824	Thioesterase
CTY05_RS04510	COG1473	amidohydrolase
CTY05_RS04530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTY05_RS04530	COG0047	phosphoribosylformylglycinamidine synthase activity
CTY05_RS04535	COG2814	Major facilitator Superfamily
CTY05_RS04545	COG1024	Enoyl-CoA hydratase
CTY05_RS04550	COG1051	belongs to the nudix hydrolase family
CTY05_RS04550	COG1056	cytidyltransferase-related domain
CTY05_RS04560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTY05_RS04575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTY05_RS04590	COG4625	pathogenesis
CTY05_RS04595	COG0583	DNA-binding transcription factor activity
CTY05_RS04600	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTY05_RS04605	COG4208	sulfate ABC transporter
CTY05_RS04610	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTY05_RS04620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTY05_RS04625	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTY05_RS04630	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTY05_RS04650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTY05_RS04665	COG0681	Belongs to the peptidase S26 family
CTY05_RS04680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTY05_RS04690	COG1381	Involved in DNA repair and RecF pathway recombination
CTY05_RS04695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTY05_RS04705	COG4221	oxidoreductase activity
CTY05_RS04735	COG0436	Aminotransferase
CTY05_RS04755	COG0556	nucleotide-excision repair
CTY05_RS04810	COG2070	2-Nitropropane dioxygenase
CTY05_RS04840	COG1215	transferase activity, transferring glycosyl groups
CTY05_RS04855	COG0415	Belongs to the DNA photolyase family
CTY05_RS04865	COG1252	NADH dehydrogenase
CTY05_RS04870	COG1686	Belongs to the peptidase S11 family
CTY05_RS04885	COG1187	pseudouridine synthase activity
CTY05_RS04910	COG0477	Major facilitator Superfamily
CTY05_RS04915	COG0583	DNA-binding transcription factor activity
CTY05_RS04920	COG1823	symporter activity
CTY05_RS04930	COG0612	Peptidase, M16
CTY05_RS04960	COG1203	CRISPR-associated helicase, Cas3
CTY05_RS04985	COG0352	thiamine-phosphate diphosphorylase activity
CTY05_RS05020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTY05_RS05035	COG1309	transcriptional regulator
CTY05_RS05045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTY05_RS05050	COG0076	glutamate decarboxylase activity
CTY05_RS05060	COG1522	sequence-specific DNA binding
CTY05_RS05065	COG3961	Belongs to the TPP enzyme family
CTY05_RS05070	COG1113	amino acid transport
CTY05_RS05075	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTY05_RS05080	COG0573	inorganic phosphate transmembrane transporter activity
CTY05_RS05090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTY05_RS05095	COG0616	signal peptide processing
CTY05_RS05130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTY05_RS05135	COG1686	Belongs to the peptidase S11 family
CTY05_RS05160	COG0583	DNA-binding transcription factor activity
CTY05_RS05165	COG1067	ATP-dependent peptidase activity
CTY05_RS05190	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CTY05_RS05210	COG1966	Carbon starvation protein
CTY05_RS05215	COG2879	small protein
CTY05_RS05265	COG1741	Belongs to the pirin family
CTY05_RS05275	COG2964	Protein conserved in bacteria
CTY05_RS05290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTY05_RS05295	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTY05_RS05300	COG4605	iron ion homeostasis
CTY05_RS05305	COG4604	ABC transporter, ATP-binding protein
CTY05_RS05310	COG4607	ABC-type enterochelin transport system periplasmic component
CTY05_RS05315	COG4774	siderophore transport
CTY05_RS05325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTY05_RS05330	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTY05_RS05335	COG3433	isochorismatase activity
CTY05_RS05335	COG1535	isochorismatase
CTY05_RS05350	COG1132	(ABC) transporter
CTY05_RS05355	COG1132	(ABC) transporter
CTY05_RS05360	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTY05_RS05370	COG1169	isochorismate synthase
CTY05_RS05385	COG3739	integral membrane protein
CTY05_RS05405	COG0302	gtp cyclohydrolase
CTY05_RS05415	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTY05_RS05445	COG0308	aminopeptidase N
CTY05_RS05450	COG0512	Glutamine amidotransferase of anthranilate synthase
CTY05_RS05465	COG0174	glutamine synthetase
CTY05_RS05475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTY05_RS05510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTY05_RS05515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTY05_RS05520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTY05_RS05540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTY05_RS05545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTY05_RS05550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTY05_RS05565	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS05570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTY05_RS05575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTY05_RS05585	COG2223	nitrite transmembrane transporter activity
CTY05_RS05595	COG0024	Methionine aminopeptidase
CTY05_RS05600	COG0052	Belongs to the universal ribosomal protein uS2 family
CTY05_RS05615	COG2207	Transcriptional regulator
CTY05_RS05640	COG2951	lytic endotransglycosylase activity
CTY05_RS05645	COG0772	Belongs to the SEDS family
CTY05_RS05660	COG0842	Transport permease protein
CTY05_RS05665	COG1131	(ABC) transporter
CTY05_RS05710	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS05725	COG4215	(ABC) transporter
CTY05_RS05730	COG4160	amino acid transport
CTY05_RS05735	COG4598	ABC transporter
CTY05_RS05745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTY05_RS05750	COG0826	peptidase U32
CTY05_RS05755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTY05_RS05770	COG1720	tRNA m6t6A37 methyltransferase activity
CTY05_RS05780	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTY05_RS05795	COG0642	Histidine kinase
CTY05_RS05805	COG0494	nUDIX hydrolase
CTY05_RS05815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTY05_RS05820	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTY05_RS05825	COG3139	Protein of unknown function (DUF1315)
CTY05_RS05830	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTY05_RS05840	COG1301	dicarboxylic acid transport
CTY05_RS05845	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS05850	COG2819	hydrolase of the alpha beta superfamily
CTY05_RS05860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTY05_RS05870	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTY05_RS05875	COG1234	tRNA 3'-trailer cleavage
CTY05_RS05900	COG2363	Small membrane protein
CTY05_RS05920	COG0513	Belongs to the DEAD box helicase family
CTY05_RS05930	COG0778	Nitroreductase
CTY05_RS05960	COG1286	toxin biosynthetic process
CTY05_RS05985	COG4783	chaperone-mediated protein folding
CTY05_RS05990	COG1610	YqeY-like protein
CTY05_RS06090	COG3111	PFAM Bacterial OB fold (BOF) protein
CTY05_RS06115	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTY05_RS06120	COG0786	glutamate:sodium symporter activity
CTY05_RS06130	COG0583	DNA-binding transcription factor activity
CTY05_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS06155	COG2186	Transcriptional regulator
CTY05_RS06215	COG0477	Major facilitator Superfamily
CTY05_RS06240	COG2995	paraquat-inducible protein a
CTY05_RS06245	COG3008	intermembrane lipid transfer
CTY05_RS06245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CTY05_RS06255	COG2351	hydroxyisourate hydrolase activity
CTY05_RS06295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTY05_RS06305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CTY05_RS06310	COG0642	Histidine kinase
CTY05_RS06315	COG0745	RESPONSE REGULATOR receiver
CTY05_RS06335	COG1794	racemase activity, acting on amino acids and derivatives
CTY05_RS06365	COG1301	dicarboxylic acid transport
CTY05_RS06375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTY05_RS06380	COG2011	ABC-type metal ion transport system permease component
CTY05_RS06385	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTY05_RS06390	COG1464	Belongs to the NlpA lipoprotein family
CTY05_RS06395	COG0151	Belongs to the GarS family
CTY05_RS06400	COG0138	bifunctional purine biosynthesis protein purh
CTY05_RS06405	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTY05_RS06435	COG2308	Evidence 4 Homologs of previously reported genes of
CTY05_RS06445	COG1305	Transglutaminase-like
CTY05_RS06455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTY05_RS06460	COG0305	Participates in initiation and elongation during chromosome replication
CTY05_RS06485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTY05_RS06495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTY05_RS06500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTY05_RS06525	COG1649	PFAM Uncharacterised BCR, COG1649
CTY05_RS06525	COG0726	polysaccharide deacetylase
CTY05_RS06530	COG1215	transferase activity, transferring glycosyl groups
CTY05_RS06535	COG3658	cytochrome
CTY05_RS06545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTY05_RS06565	COG0583	DNA-binding transcription factor activity
CTY05_RS06585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTY05_RS06590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTY05_RS06605	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS06610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTY05_RS06615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS06640	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTY05_RS06645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTY05_RS06655	COG2205	protein histidine kinase activity
CTY05_RS06660	COG0745	RESPONSE REGULATOR receiver
CTY05_RS06665	COG0174	glutamine synthetase
CTY05_RS06685	COG0729	surface antigen
CTY05_RS06715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTY05_RS06720	COG2814	Major facilitator Superfamily
CTY05_RS06735	COG0583	DNA-binding transcription factor activity
CTY05_RS06750	COG1187	pseudouridine synthase activity
CTY05_RS06770	COG0802	atpase or kinase
CTY05_RS06775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTY05_RS06785	COG1923	regulation of RNA biosynthetic process
CTY05_RS06790	COG0697	spore germination
CTY05_RS06815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTY05_RS06820	COG0519	Catalyzes the synthesis of GMP from XMP
CTY05_RS06820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTY05_RS06825	COG4302	ethanolamine ammonia-lyase activity
CTY05_RS06830	COG4303	Ethanolamine ammonia lyase large subunit
CTY05_RS06835	COG0531	amino acid
CTY05_RS06855	COG1454	alcohol dehydrogenase
CTY05_RS06860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTY05_RS06885	COG0308	aminopeptidase N
CTY05_RS06925	COG1605	Chorismate mutase
CTY05_RS06945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
CTY05_RS06965	COG1309	transcriptional regulator
CTY05_RS06975	COG0668	transmembrane transport
CTY05_RS07005	COG4773	Receptor
CTY05_RS07025	COG0488	(ABC) transporter
CTY05_RS07030	COG0589	response to stress
CTY05_RS07045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTY05_RS07055	COG3135	benzoate transporter
CTY05_RS07060	COG1522	sequence-specific DNA binding
CTY05_RS07070	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTY05_RS07075	COG0583	DNA-binding transcription factor activity
CTY05_RS07085	COG0183	Belongs to the thiolase family
CTY05_RS07095	COG2030	dehydratase
CTY05_RS07100	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTY05_RS07115	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTY05_RS07125	COG0824	Thioesterase
CTY05_RS07130	COG1454	alcohol dehydrogenase
CTY05_RS07140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTY05_RS07160	COG0069	glutamate synthase activity
CTY05_RS07180	COG2814	Major facilitator Superfamily
CTY05_RS07195	COG0511	ligase activity, forming carbon-carbon bonds
CTY05_RS07215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTY05_RS07215	COG1116	anion transmembrane transporter activity
CTY05_RS07220	COG0745	RESPONSE REGULATOR receiver
CTY05_RS07230	COG2146	nitrite reductase [NAD(P)H] activity
CTY05_RS07230	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTY05_RS07235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTY05_RS07240	COG0243	molybdopterin cofactor binding
CTY05_RS07250	COG0243	molybdopterin cofactor binding
CTY05_RS07255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTY05_RS07270	COG0315	cyclic pyranopterin monophosphate synthase activity
CTY05_RS07270	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTY05_RS07275	COG0303	'Molybdopterin
CTY05_RS07290	COG0697	spore germination
CTY05_RS07310	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTY05_RS07315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTY05_RS07375	COG2204	response regulator
CTY05_RS07380	COG3852	Histidine kinase
CTY05_RS07405	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTY05_RS07410	COG0575	Belongs to the CDS family
CTY05_RS07445	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTY05_RS07460	COG2137	regulation of response to DNA damage stimulus
CTY05_RS07470	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTY05_RS07475	COG1011	Hydrolase
CTY05_RS07500	COG1522	sequence-specific DNA binding
CTY05_RS07510	COG1113	amino acid transport
CTY05_RS07525	COG0659	secondary active sulfate transmembrane transporter activity
CTY05_RS07530	COG2135	peptidase activity
CTY05_RS07545	COG5001	Diguanylate cyclase
CTY05_RS07545	COG3300	MHYT domain
CTY05_RS07565	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTY05_RS07565	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTY05_RS07565	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTY05_RS07570	COG1105	Belongs to the carbohydrate kinase PfkB family
CTY05_RS07575	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTY05_RS07575	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTY05_RS07605	COG0024	Methionine aminopeptidase
CTY05_RS07610	COG0583	DNA-binding transcription factor activity
CTY05_RS07620	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTY05_RS07625	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTY05_RS07630	COG0517	IMP dehydrogenase activity
CTY05_RS07630	COG0516	GMP reductase activity
CTY05_RS07655	COG0552	protein localization to endoplasmic reticulum
CTY05_RS07665	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTY05_RS07675	COG4890	Cyd operon protein YbgT
CTY05_RS07680	COG1294	oxidase, subunit
CTY05_RS07695	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTY05_RS07705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTY05_RS07710	COG4774	siderophore transport
CTY05_RS07725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTY05_RS07730	COG0569	domain protein
CTY05_RS07735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTY05_RS07765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTY05_RS07770	COG0542	response to heat
CTY05_RS07795	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTY05_RS07795	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS07840	COG2323	membrane
CTY05_RS07845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTY05_RS07855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTY05_RS07860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTY05_RS07865	COG0183	Belongs to the thiolase family
CTY05_RS07870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTY05_RS07875	COG0596	Alpha beta hydrolase
CTY05_RS07880	COG2271	Major facilitator Superfamily
CTY05_RS07885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTY05_RS07890	COG3485	protocatechuate 3,4-dioxygenase
CTY05_RS07895	COG3485	protocatechuate 3,4-dioxygenase
CTY05_RS07900	COG0710	3-dehydroquinate dehydratase activity
CTY05_RS07905	COG3420	alginic acid biosynthetic process
CTY05_RS07910	COG3659	wide pore channel activity
CTY05_RS07915	COG4993	Dehydrogenase
CTY05_RS07925	COG2391	methyltransferase activity
CTY05_RS07940	COG1414	Transcriptional regulator
CTY05_RS07945	COG0583	DNA-binding transcription factor activity
CTY05_RS07950	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS07975	COG2814	Major facilitator Superfamily
CTY05_RS07985	COG0154	amidase activity
CTY05_RS08005	COG4638	Rieske (2fe-2S)
CTY05_RS08015	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS08025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS08035	COG3733	amine oxidase
CTY05_RS08045	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS08055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTY05_RS08060	COG0183	Belongs to the thiolase family
CTY05_RS08070	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTY05_RS08075	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTY05_RS08085	COG4829	muconolactone delta-isomerase
CTY05_RS08090	COG4948	Mandelate Racemase Muconate Lactonizing
CTY05_RS08095	COG0583	DNA-binding transcription factor activity
CTY05_RS08105	COG2186	Transcriptional regulator
CTY05_RS08125	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS08140	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS08140	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTY05_RS08180	COG1309	transcriptional regulator
CTY05_RS08195	COG4689	acetoacetate decarboxylase
CTY05_RS08205	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS08225	COG1335	isochorismatase
CTY05_RS08230	COG0583	DNA-binding transcription factor activity
CTY05_RS08240	COG0475	glutathione-regulated potassium exporter activity
CTY05_RS08240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTY05_RS08250	COG1473	amidohydrolase
CTY05_RS08320	COG2188	Transcriptional regulator
CTY05_RS08335	COG0583	DNA-binding transcription factor activity
CTY05_RS08350	COG1566	PFAM secretion protein HlyD family protein
CTY05_RS08365	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS08370	COG0129	dihydroxy-acid dehydratase activity
CTY05_RS08380	COG0583	DNA-binding transcription factor activity
CTY05_RS08385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTY05_RS08395	COG2084	Dehydrogenase
CTY05_RS08410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTY05_RS08470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTY05_RS08485	COG0556	nucleotide-excision repair
CTY05_RS08525	COG1073	alpha beta
CTY05_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS08550	COG2207	Transcriptional regulator
CTY05_RS08560	COG2205	protein histidine kinase activity
CTY05_RS08565	COG0745	RESPONSE REGULATOR receiver
CTY05_RS08570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS08575	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTY05_RS08580	COG1538	Outer membrane efflux protein
CTY05_RS08590	COG2072	flavoprotein involved in K transport
CTY05_RS08600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTY05_RS08620	COG3539	Fimbrial protein
CTY05_RS08645	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTY05_RS08655	COG0753	catalase activity
CTY05_RS08670	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTY05_RS08735	COG1535	isochorismatase
CTY05_RS08735	COG3433	isochorismatase activity
CTY05_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS08745	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTY05_RS08750	COG4149	molybdate abc transporter
CTY05_RS08755	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTY05_RS08765	COG4638	Rieske (2fe-2S)
CTY05_RS08770	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTY05_RS08775	COG0543	2 iron, 2 sulfur cluster binding
CTY05_RS08775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTY05_RS08790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS08815	COG2207	Transcriptional regulator
CTY05_RS08820	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS08825	COG2610	gluconate transmembrane transporter activity
CTY05_RS08835	COG0583	DNA-binding transcription factor activity
CTY05_RS08850	COG2031	fatty acid transporter
CTY05_RS08855	COG0183	Belongs to the thiolase family
CTY05_RS08860	COG0583	DNA-binding transcription factor activity
CTY05_RS08865	COG0583	DNA-binding transcription factor activity
CTY05_RS08880	COG1027	Aspartate ammonia-lyase
CTY05_RS08890	COG0477	Major facilitator Superfamily
CTY05_RS08910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTY05_RS08915	COG4521	taurine ABC transporter
CTY05_RS08930	COG2188	Transcriptional regulator
CTY05_RS08940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTY05_RS08945	COG1733	regulation of RNA biosynthetic process
CTY05_RS08950	COG3708	Transcriptional regulator
CTY05_RS08950	COG2207	Transcriptional regulator
CTY05_RS08965	COG0730	response to heat
CTY05_RS08975	COG3453	Protein conserved in bacteria
CTY05_RS08975	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTY05_RS08985	COG3781	membrane
CTY05_RS08990	COG1063	alcohol dehydrogenase
CTY05_RS09000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTY05_RS09005	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTY05_RS09010	COG0022	dehydrogenase e1 component
CTY05_RS09015	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTY05_RS09020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTY05_RS09035	COG3706	GGDEF domain
CTY05_RS09050	COG0133	tryptophan synthase activity
CTY05_RS09060	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTY05_RS09095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTY05_RS09120	COG2226	methyltransferase
CTY05_RS09175	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTY05_RS09180	COG4773	Receptor
CTY05_RS09200	COG0730	response to heat
CTY05_RS09205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTY05_RS09220	COG0406	alpha-ribazole phosphatase activity
CTY05_RS09225	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTY05_RS09240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTY05_RS09270	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTY05_RS09280	COG4264	IucA IucC family
CTY05_RS09285	COG4264	IucA IucC family
CTY05_RS09290	COG2814	Major facilitator Superfamily
CTY05_RS09305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTY05_RS09320	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS09325	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS09330	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTY05_RS09335	COG2207	Transcriptional regulator
CTY05_RS09340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTY05_RS09345	COG0776	regulation of translation
CTY05_RS09370	COG0822	iron-sulfur transferase activity
CTY05_RS09375	COG0316	Belongs to the HesB IscA family
CTY05_RS09405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTY05_RS09425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTY05_RS09430	COG0702	epimerase
CTY05_RS09465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTY05_RS09475	COG0339	signal peptide processing
CTY05_RS09495	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
CTY05_RS09520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTY05_RS09525	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTY05_RS09555	COG0776	regulation of translation
CTY05_RS09620	COG0084	hydrolase, TatD family'
CTY05_RS09640	COG1663	tetraacyldisaccharide 4'-kinase activity
CTY05_RS09645	COG1132	(ABC) transporter
CTY05_RS09655	COG0811	peptide transport
CTY05_RS09660	COG1475	DNA binding
CTY05_RS09665	COG1192	Involved in chromosome partitioning
CTY05_RS09675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTY05_RS09690	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTY05_RS09695	COG0191	fructose-bisphosphate aldolase activity
CTY05_RS09715	COG0424	maF-like protein
CTY05_RS09720	COG2850	peptidyl-arginine hydroxylation
CTY05_RS09730	COG0640	Transcriptional regulator
CTY05_RS09740	COG3619	membrane
CTY05_RS09745	COG3122	Protein conserved in bacteria
CTY05_RS09750	COG1132	(ABC) transporter
CTY05_RS09770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTY05_RS09775	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTY05_RS09785	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTY05_RS09785	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTY05_RS09785	COG0506	proline dehydrogenase activity
CTY05_RS09790	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTY05_RS09805	COG3698	Phosphodiester glycosidase
CTY05_RS09815	COG2353	YceI-like domain
CTY05_RS09825	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTY05_RS09870	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTY05_RS09870	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTY05_RS09895	COG3539	Fimbrial protein
CTY05_RS09900	COG3121	Chaperone
CTY05_RS09930	COG0697	spore germination
CTY05_RS09940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTY05_RS09950	COG0583	DNA-binding transcription factor activity
CTY05_RS09970	COG1309	transcriptional regulator
CTY05_RS09985	COG1522	sequence-specific DNA binding
CTY05_RS09995	COG1126	abc transporter atp-binding protein
CTY05_RS10000	COG0765	amino acid transport
CTY05_RS10005	COG0765	amino acid transport
CTY05_RS10035	COG1464	Belongs to the NlpA lipoprotein family
CTY05_RS10045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTY05_RS10050	COG2011	ABC-type metal ion transport system permease component
CTY05_RS10055	COG0012	GTP binding
CTY05_RS10080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTY05_RS10120	COG0386	Belongs to the glutathione peroxidase family
CTY05_RS10130	COG0436	Aminotransferase
CTY05_RS10135	COG1301	dicarboxylic acid transport
CTY05_RS10170	COG3634	alkyl hydroperoxide reductase activity
CTY05_RS10185	COG0583	DNA-binding transcription factor activity
CTY05_RS10190	COG0798	PFAM Bile acid sodium symporter
CTY05_RS10195	COG0640	Transcriptional regulator
CTY05_RS10210	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTY05_RS10220	COG0583	DNA-binding transcription factor activity
CTY05_RS10230	COG1953	Uracil, thiamine, allantoin
CTY05_RS10240	COG2175	clavaminate synthase activity
CTY05_RS10245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTY05_RS10250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTY05_RS10255	COG4521	taurine ABC transporter
CTY05_RS10265	COG0477	Major facilitator Superfamily
CTY05_RS10290	COG1271	oxidase subunit
CTY05_RS10295	COG1294	oxidase, subunit
CTY05_RS10305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTY05_RS10325	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTY05_RS10345	COG3052	prosthetic group binding
CTY05_RS10350	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTY05_RS10360	COG2814	Major facilitator Superfamily
CTY05_RS10375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTY05_RS10380	COG1346	cytolysis
CTY05_RS10390	COG0583	DNA-binding transcription factor activity
CTY05_RS10395	COG0625	glutathione transferase activity
CTY05_RS10400	COG0625	glutathione transferase activity
CTY05_RS10405	COG0583	DNA-binding transcription factor activity
CTY05_RS10420	COG1045	serine acetyltransferase
CTY05_RS10425	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTY05_RS10430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTY05_RS10435	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS10445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTY05_RS10450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTY05_RS10455	COG1126	abc transporter atp-binding protein
CTY05_RS10460	COG0765	amino acid transport
CTY05_RS10465	COG0765	amino acid transport
CTY05_RS10485	COG2205	protein histidine kinase activity
CTY05_RS10485	COG0784	Response regulator, receiver
CTY05_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS10570	COG0583	DNA-binding transcription factor activity
CTY05_RS10590	COG0318	PFAM AMP-dependent synthetase and ligase
CTY05_RS10595	COG1309	transcriptional regulator
CTY05_RS10600	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS10605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTY05_RS10610	COG1024	Enoyl-CoA hydratase
CTY05_RS10615	COG4770	biotin carboxylase activity
CTY05_RS10625	COG0583	DNA-binding transcription factor activity
CTY05_RS10640	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS10650	COG2814	Major facilitator Superfamily
CTY05_RS10660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTY05_RS10665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTY05_RS10670	COG2814	Major facilitator Superfamily
CTY05_RS10675	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS10680	COG1024	Enoyl-CoA hydratase
CTY05_RS10685	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS10690	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTY05_RS10695	COG0183	Belongs to the thiolase family
CTY05_RS10705	COG2814	Major facilitator Superfamily
CTY05_RS10715	COG1024	Enoyl-CoA hydratase
CTY05_RS10725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTY05_RS10730	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS10735	COG2814	Major facilitator Superfamily
CTY05_RS10740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTY05_RS10745	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTY05_RS10760	COG3842	ATPase activity
CTY05_RS10765	COG1840	ABC-type Fe3 transport system, periplasmic component
CTY05_RS10775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTY05_RS10780	COG1414	Transcriptional regulator
CTY05_RS10790	COG0583	DNA-binding transcription factor activity
CTY05_RS10795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTY05_RS10800	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS10810	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTY05_RS10820	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS10825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTY05_RS10830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS10835	COG2267	carboxylic ester hydrolase activity
CTY05_RS10855	COG3038	cytochrome b561
CTY05_RS10860	COG0753	catalase activity
CTY05_RS10865	COG2271	Major facilitator Superfamily
CTY05_RS10870	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTY05_RS10875	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTY05_RS10905	COG1278	Cold shock
CTY05_RS10940	COG0210	DNA helicase
CTY05_RS10945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CTY05_RS10950	COG2050	protein possibly involved in aromatic compounds catabolism
CTY05_RS10960	COG3327	negative regulation of DNA-templated transcription, initiation
CTY05_RS10965	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTY05_RS10970	COG0183	Belongs to the thiolase family
CTY05_RS10975	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTY05_RS10980	COG1024	Enoyl-CoA hydratase
CTY05_RS10985	COG1024	Enoyl-CoA hydratase
CTY05_RS10990	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTY05_RS10995	COG2151	metal-sulfur cluster biosynthetic enzyme
CTY05_RS11000	COG3396	Phenylacetate-CoA oxygenase
CTY05_RS11005	COG3460	Phenylacetate-CoA oxygenase
CTY05_RS11010	COG3396	Phenylacetate-CoA oxygenase
CTY05_RS11015	COG2030	dehydratase
CTY05_RS11015	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS11020	COG1760	l-serine dehydratase
CTY05_RS11025	COG0531	amino acid
CTY05_RS11030	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS11055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTY05_RS11075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTY05_RS11090	COG0789	Transcriptional regulator
CTY05_RS11100	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CTY05_RS11115	COG2807	transmembrane transport
CTY05_RS11120	COG0590	tRNA wobble adenosine to inosine editing
CTY05_RS11240	COG1116	anion transmembrane transporter activity
CTY05_RS11245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTY05_RS11255	COG0864	Transcriptional regulator
CTY05_RS11265	COG1733	regulation of RNA biosynthetic process
CTY05_RS11270	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTY05_RS11275	COG0439	Biotin carboxylase
CTY05_RS11290	COG1063	alcohol dehydrogenase
CTY05_RS11300	COG1309	transcriptional regulator
CTY05_RS11330	COG0038	chloride channel
CTY05_RS11335	COG4770	biotin carboxylase activity
CTY05_RS11355	COG1914	H( )-stimulated, divalent metal cation uptake system
CTY05_RS11360	COG0583	DNA-binding transcription factor activity
CTY05_RS11380	COG3209	COG3209 Rhs family protein
CTY05_RS11430	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTY05_RS11450	COG2814	Major facilitator Superfamily
CTY05_RS11465	COG1560	Kdo2-lipid A biosynthetic process
CTY05_RS11475	COG5006	permease, DMT superfamily
CTY05_RS11480	COG1522	sequence-specific DNA binding
CTY05_RS11495	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTY05_RS11505	COG4122	O-methyltransferase activity
CTY05_RS11535	COG1538	Outer membrane efflux protein
CTY05_RS11540	COG1137	ATPase activity
CTY05_RS11545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTY05_RS11555	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTY05_RS11610	COG5434	Belongs to the glycosyl hydrolase 28 family
CTY05_RS11630	COG3566	protein conserved in bacteria
CTY05_RS11650	COG3567	Phage-associated protein, HI1409 family
CTY05_RS11655	COG5410	chromosome segregation
CTY05_RS11730	COG2814	Major facilitator Superfamily
CTY05_RS11770	COG1278	Cold shock
CTY05_RS11775	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS11810	COG1570	exodeoxyribonuclease VII activity
CTY05_RS11865	COG0583	DNA-binding transcription factor activity
CTY05_RS11870	COG4638	Rieske (2fe-2S)
CTY05_RS11875	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTY05_RS11880	COG0633	Ferredoxin
CTY05_RS11880	COG0543	2 iron, 2 sulfur cluster binding
CTY05_RS11885	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS11890	COG3135	benzoate transporter
CTY05_RS11895	COG2814	Major facilitator Superfamily
CTY05_RS11910	COG1643	Atp-dependent helicase
CTY05_RS11915	COG0450	alkyl hydroperoxide reductase
CTY05_RS11925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTY05_RS11935	COG3634	alkyl hydroperoxide reductase activity
CTY05_RS11955	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTY05_RS11960	COG0625	glutathione transferase activity
CTY05_RS11970	COG2885	chlorophyll binding
CTY05_RS12005	COG0542	response to heat
CTY05_RS12020	COG1765	OsmC-like protein
CTY05_RS12030	COG0667	Aldo Keto reductase
CTY05_RS12045	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTY05_RS12055	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTY05_RS12065	COG0527	aspartate kinase activity
CTY05_RS12075	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTY05_RS12085	COG3038	cytochrome b561
CTY05_RS12090	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTY05_RS12095	COG2252	PERMEase
CTY05_RS12105	COG2072	flavoprotein involved in K transport
CTY05_RS12120	COG1741	Belongs to the pirin family
CTY05_RS12125	COG1309	transcriptional regulator
CTY05_RS12135	COG0300	oxidoreductase activity
CTY05_RS12140	COG2072	flavoprotein involved in K transport
CTY05_RS12145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CTY05_RS12190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTY05_RS12205	COG2814	Major facilitator Superfamily
CTY05_RS12210	COG1024	Enoyl-CoA hydratase
CTY05_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS12225	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS12250	COG2186	Transcriptional regulator
CTY05_RS12255	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS12265	COG4948	Mandelate Racemase Muconate Lactonizing
CTY05_RS12270	COG2271	Major facilitator Superfamily
CTY05_RS12275	COG2721	sulfolactate sulfo-lyase activity
CTY05_RS12280	COG0697	spore germination
CTY05_RS12310	COG1113	amino acid transport
CTY05_RS12330	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS12350	COG0531	amino acid
CTY05_RS12360	COG1113	amino acid transport
CTY05_RS12400	COG3209	COG3209 Rhs family protein
CTY05_RS12435	COG1902	pentaerythritol trinitrate reductase activity
CTY05_RS12435	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTY05_RS12445	COG5001	Diguanylate cyclase
CTY05_RS12445	COG2203	Gaf domain
CTY05_RS12445	COG3706	GGDEF domain
CTY05_RS12445	COG4251	negative regulation of phosphorylation
CTY05_RS12455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTY05_RS12510	COG4172	Belongs to the ABC transporter superfamily
CTY05_RS12515	COG4239	(ABC) transporter, permease
CTY05_RS12520	COG4174	ABC transporter (Permease)
CTY05_RS12530	COG0741	lytic transglycosylase activity
CTY05_RS12530	COG1388	LysM domain
CTY05_RS12530	COG0741	lytic transglycosylase activity
CTY05_RS12530	COG1388	LysM domain
CTY05_RS12535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTY05_RS12575	COG0583	DNA-binding transcription factor activity
CTY05_RS12580	COG1279	arginine transmembrane transporter activity
CTY05_RS12600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTY05_RS12605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTY05_RS12610	COG0006	proline dipeptidase activity
CTY05_RS12645	COG1278	Cold shock
CTY05_RS12720	COG0739	heme binding
CTY05_RS12920	COG0464	growth
CTY05_RS12995	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTY05_RS13025	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTY05_RS13030	COG2878	Part of a membrane complex involved in electron transport
CTY05_RS13035	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTY05_RS13055	COG0768	penicillin binding
CTY05_RS13060	COG0742	ribosomal rna small subunit methyltransferase
CTY05_RS13075	COG0830	nickel cation binding
CTY05_RS13085	COG0804	urea catabolic process
CTY05_RS13125	COG1253	flavin adenine dinucleotide binding
CTY05_RS13135	COG2851	Citrate transporter
CTY05_RS13185	COG1773	rubredoxin
CTY05_RS13190	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTY05_RS13200	COG0583	DNA-binding transcription factor activity
CTY05_RS13230	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTY05_RS13235	COG4181	ATPase activity
CTY05_RS13280	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTY05_RS13300	COG0306	phosphate transporter
CTY05_RS13310	COG3958	Transketolase
CTY05_RS13315	COG3959	Transketolase, thiamine diphosphate binding domain
CTY05_RS13320	COG2271	Major facilitator Superfamily
CTY05_RS13325	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS13330	COG0583	DNA-binding transcription factor activity
CTY05_RS13350	COG2223	nitrite transmembrane transporter activity
CTY05_RS13355	COG2207	Transcriptional regulator
CTY05_RS13360	COG2066	Belongs to the glutaminase family
CTY05_RS13365	COG0242	peptide deformylase activity
CTY05_RS13370	COG0477	Major facilitator Superfamily
CTY05_RS13380	COG0028	Belongs to the TPP enzyme family
CTY05_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS13400	COG2267	carboxylic ester hydrolase activity
CTY05_RS13410	COG2271	Major facilitator Superfamily
CTY05_RS13415	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTY05_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS13445	COG1414	Transcriptional regulator
CTY05_RS13460	COG1024	Enoyl-CoA hydratase
CTY05_RS13470	COG1215	transferase activity, transferring glycosyl groups
CTY05_RS13475	COG1649	PFAM Uncharacterised BCR, COG1649
CTY05_RS13475	COG0726	polysaccharide deacetylase
CTY05_RS13485	COG4681	YaeQ
CTY05_RS13495	COG0523	cobalamin synthesis protein
CTY05_RS13505	COG1607	acyl-coa hydrolase
CTY05_RS13515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTY05_RS13520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTY05_RS13525	COG1309	transcriptional regulator
CTY05_RS13550	COG2040	homocysteine
CTY05_RS13555	COG0531	amino acid
CTY05_RS13580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTY05_RS13585	COG0477	Major facilitator Superfamily
CTY05_RS13605	COG0084	hydrolase, TatD family'
CTY05_RS13635	COG0405	Gamma-glutamyltransferase
CTY05_RS13640	COG2814	Major facilitator Superfamily
CTY05_RS13650	COG2050	protein possibly involved in aromatic compounds catabolism
CTY05_RS13665	COG1090	epimerase
CTY05_RS13685	COG0420	3'-5' exonuclease activity
CTY05_RS13710	COG0735	belongs to the Fur family
CTY05_RS13715	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTY05_RS13740	COG0121	glutamine amidotransferase
CTY05_RS13755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTY05_RS13765	COG0210	DNA helicase
CTY05_RS13770	COG2885	chlorophyll binding
CTY05_RS13775	COG0204	Acyl-transferase
CTY05_RS13790	COG2894	cell division
CTY05_RS13805	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS13810	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTY05_RS13810	COG1674	ftsk spoiiie
CTY05_RS13815	COG0492	ferredoxin-NADP+ reductase activity
CTY05_RS13820	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTY05_RS13830	COG0456	acetyltransferase
CTY05_RS13875	COG1981	membrane
CTY05_RS13890	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTY05_RS13890	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTY05_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS13920	COG0657	acetylesterase activity
CTY05_RS13930	COG0473	3-isopropylmalate dehydrogenase activity
CTY05_RS13935	COG0583	DNA-binding transcription factor activity
CTY05_RS13955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTY05_RS13980	COG0564	pseudouridine synthase activity
CTY05_RS13990	COG0358	DNA primase activity
CTY05_RS14005	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTY05_RS14035	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTY05_RS14065	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTY05_RS14075	COG0351	phosphomethylpyrimidine kinase
CTY05_RS14075	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTY05_RS14075	COG0352	thiamine-phosphate diphosphorylase activity
CTY05_RS14080	COG1652	LysM domain
CTY05_RS14105	COG1399	metal-binding, possibly nucleic acid-binding protein
CTY05_RS14110	COG3101	peptidyl-lysine hydroxylation
CTY05_RS14115	COG0009	L-threonylcarbamoyladenylate synthase
CTY05_RS14120	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTY05_RS14125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTY05_RS14140	COG4106	trans-aconitate 2-methyltransferase activity
CTY05_RS14155	COG2226	methyltransferase
CTY05_RS14155	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTY05_RS14155	COG0596	Alpha beta hydrolase
CTY05_RS14160	COG1877	trehalose-phosphatase activity
CTY05_RS14165	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTY05_RS14170	COG2223	nitrite transmembrane transporter activity
CTY05_RS14190	COG1196	nuclear chromosome segregation
CTY05_RS14200	COG0730	response to heat
CTY05_RS14215	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTY05_RS14225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTY05_RS14285	COG0489	protein tyrosine kinase activity
CTY05_RS14295	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTY05_RS14295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTY05_RS14325	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTY05_RS14330	COG2081	HI0933 family
CTY05_RS14340	COG0668	transmembrane transport
CTY05_RS14360	COG0583	DNA-binding transcription factor activity
CTY05_RS14385	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTY05_RS14390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTY05_RS14420	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTY05_RS14460	COG0745	RESPONSE REGULATOR receiver
CTY05_RS14480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTY05_RS14490	COG0384	phenazine biosynthesis protein PhzF
CTY05_RS14520	COG1309	transcriptional regulator
CTY05_RS14530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTY05_RS14545	COG0583	DNA-binding transcription factor activity
CTY05_RS14575	COG0583	DNA-binding transcription factor activity
CTY05_RS14595	COG0583	DNA-binding transcription factor activity
CTY05_RS14600	COG1053	succinate dehydrogenase
CTY05_RS14610	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTY05_RS14615	COG2814	Major facilitator Superfamily
CTY05_RS14620	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS14625	COG0583	DNA-binding transcription factor activity
CTY05_RS14630	COG1063	alcohol dehydrogenase
CTY05_RS14665	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTY05_RS14670	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTY05_RS14675	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTY05_RS14690	COG3667	copper resistance
CTY05_RS14695	COG2132	Multicopper oxidase
CTY05_RS14705	COG0561	phosphatase activity
CTY05_RS14710	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTY05_RS14720	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CTY05_RS14735	COG1214	PFAM Peptidase M22, glycoprotease
CTY05_RS14785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTY05_RS14795	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTY05_RS14800	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTY05_RS14805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTY05_RS14865	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTY05_RS14875	COG1846	Transcriptional regulator
CTY05_RS14880	COG1764	response to oxidative stress
CTY05_RS14920	COG0037	tRNA processing
CTY05_RS14930	COG0248	Ppx GppA phosphatase
CTY05_RS14960	COG0072	phenylalanine-tRNA ligase activity
CTY05_RS14995	COG1238	metal cluster binding
CTY05_RS15000	COG0625	glutathione transferase activity
CTY05_RS15015	COG0318	PFAM AMP-dependent synthetase and ligase
CTY05_RS15020	COG3028	Belongs to the UPF0307 family
CTY05_RS15025	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTY05_RS15045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTY05_RS15050	COG0617	tRNA 3'-terminal CCA addition
CTY05_RS15055	COG1555	photosystem II stabilization
CTY05_RS15060	COG3956	TIGRFAM MazG family protein
CTY05_RS15070	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTY05_RS15090	COG5002	protein histidine kinase activity
CTY05_RS15090	COG2205	protein histidine kinase activity
CTY05_RS15090	COG0784	Response regulator, receiver
CTY05_RS15095	COG1024	Enoyl-CoA hydratase
CTY05_RS15100	COG2084	Dehydrogenase
CTY05_RS15105	COG3622	Belongs to the hyi family
CTY05_RS15135	COG0697	spore germination
CTY05_RS15145	COG2814	Major facilitator Superfamily
CTY05_RS15150	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTY05_RS15160	COG0583	DNA-binding transcription factor activity
CTY05_RS15170	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTY05_RS15180	COG0084	hydrolase, TatD family'
CTY05_RS15195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTY05_RS15230	COG0440	acetolactate synthase activity
CTY05_RS15235	COG0028	Belongs to the TPP enzyme family
CTY05_RS15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTY05_RS15265	COG1136	(ABC) transporter
CTY05_RS15265	COG0577	efflux transmembrane transporter activity
CTY05_RS15270	COG1538	Outer membrane efflux protein
CTY05_RS15285	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTY05_RS15290	COG1162	GTPase activity
CTY05_RS15300	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTY05_RS15340	COG1426	Protein conserved in bacteria
CTY05_RS15375	COG0793	Belongs to the peptidase S41A family
CTY05_RS15390	COG2267	carboxylic ester hydrolase activity
CTY05_RS15400	COG1012	belongs to the aldehyde dehydrogenase family
CTY05_RS15405	COG3265	gluconokinase activity
CTY05_RS15415	COG0800	Aldolase
CTY05_RS15425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTY05_RS15430	COG0280	phosphate acetyltransferase
CTY05_RS15430	COG0857	belongs to the CobB CobQ family
CTY05_RS15435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTY05_RS15435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTY05_RS15455	COG0740	serine-type endopeptidase activity
CTY05_RS15465	COG4774	siderophore transport
CTY05_RS15475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTY05_RS15485	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTY05_RS15485	COG2813	Specifically methylates the guanine in position
CTY05_RS15585	COG0788	formyltetrahydrofolate deformylase activity
CTY05_RS15610	COG4651	solute:proton antiporter activity
CTY05_RS15610	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTY05_RS15630	COG0724	RNA recognition motif
CTY05_RS15635	COG0210	DNA helicase
CTY05_RS15660	COG1733	regulation of RNA biosynthetic process
CTY05_RS15670	COG2900	Belongs to the SlyX family
CTY05_RS15675	COG0488	(ABC) transporter
CTY05_RS15680	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS15685	COG1560	Kdo2-lipid A biosynthetic process
CTY05_RS15695	COG1301	dicarboxylic acid transport
CTY05_RS15750	COG0473	3-isopropylmalate dehydrogenase activity
CTY05_RS15805	COG0583	DNA-binding transcription factor activity
CTY05_RS15815	COG0625	glutathione transferase activity
CTY05_RS15820	COG2378	regulation of single-species biofilm formation
CTY05_RS15825	COG0546	phosphoglycolate phosphatase activity
CTY05_RS15840	COG1530	ribonuclease E activity
CTY05_RS15845	COG0318	PFAM AMP-dependent synthetase and ligase
CTY05_RS15860	COG0583	DNA-binding transcription factor activity
CTY05_RS15865	COG4221	oxidoreductase activity
CTY05_RS15870	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTY05_RS15880	COG0534	Mate efflux family protein
CTY05_RS15895	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTY05_RS15920	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTY05_RS15920	COG0493	'glutamate synthase
CTY05_RS15930	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTY05_RS15935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTY05_RS15950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTY05_RS15960	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTY05_RS15960	COG0644	oxidoreductase
CTY05_RS15970	COG0425	Belongs to the sulfur carrier protein TusA family
CTY05_RS15975	COG4535	Mg2 and Co2 transporter CorC
CTY05_RS15985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTY05_RS16005	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTY05_RS16010	COG0475	glutathione-regulated potassium exporter activity
CTY05_RS16010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTY05_RS16025	COG0484	heat shock protein binding
CTY05_RS16030	COG0789	Transcriptional regulator
CTY05_RS16035	COG0598	Magnesium transport protein CorA
CTY05_RS16050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTY05_RS16055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTY05_RS16060	COG1074	ATP-dependent DNA helicase activity
CTY05_RS16065	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTY05_RS16085	COG2226	methyltransferase
CTY05_RS16105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTY05_RS16120	COG2111	Na H antiporter
CTY05_RS16120	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTY05_RS16125	COG1006	Multisubunit Na H antiporter MnhC subunit
CTY05_RS16130	COG0651	ATP synthesis coupled electron transport
CTY05_RS16135	COG1863	multisubunit Na H antiporter MnhE subunit
CTY05_RS16140	COG2212	antiporter activity
CTY05_RS16145	COG1320	monovalent cation:proton antiporter activity
CTY05_RS16160	COG0195	Participates in both transcription termination and antitermination
CTY05_RS16210	COG0237	dephospho-CoA kinase activity
CTY05_RS16220	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTY05_RS16235	COG0497	DNA recombination
CTY05_RS16245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTY05_RS16275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTY05_RS16275	COG2169	Transcriptional regulator
CTY05_RS16280	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTY05_RS16340	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTY05_RS16355	COG0326	Molecular chaperone. Has ATPase activity
CTY05_RS16370	COG2056	Na+-H+ antiporter family
CTY05_RS16470	COG0546	phosphoglycolate phosphatase activity
CTY05_RS16475	COG1716	ATPase activity
CTY05_RS16520	COG0181	hydroxymethylbilane synthase activity
CTY05_RS16530	COG3275	phosphorelay sensor kinase activity
CTY05_RS16550	COG1538	Outer membrane efflux protein
CTY05_RS16555	COG0697	spore germination
CTY05_RS16580	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTY05_RS16585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTY05_RS16590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTY05_RS16595	COG0772	Belongs to the SEDS family
CTY05_RS16620	COG4974	Belongs to the 'phage' integrase family
CTY05_RS16625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTY05_RS16635	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTY05_RS16645	COG2197	response regulator
CTY05_RS16660	COG0793	Belongs to the peptidase S41A family
CTY05_RS16665	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTY05_RS16670	COG0795	lipopolysaccharide-transporting ATPase activity
CTY05_RS16710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTY05_RS16710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTY05_RS16720	COG0004	ammonium transporteR
CTY05_RS16725	COG0347	Belongs to the P(II) protein family
CTY05_RS16735	COG0606	chelatase, subunit chli
CTY05_RS16740	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTY05_RS16750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTY05_RS16765	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTY05_RS16780	COG0318	PFAM AMP-dependent synthetase and ligase
CTY05_RS16790	COG0477	Major facilitator Superfamily
CTY05_RS16795	COG2860	membrane
CTY05_RS16800	COG3012	SEC-C Motif Domain Protein
CTY05_RS16805	COG1253	flavin adenine dinucleotide binding
CTY05_RS16815	COG0477	Major facilitator Superfamily
CTY05_RS16825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTY05_RS16860	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTY05_RS16870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTY05_RS16905	COG1309	transcriptional regulator
CTY05_RS16940	COG0758	DNA mediated transformation
CTY05_RS16950	COG0697	spore germination
CTY05_RS16955	COG1309	transcriptional regulator
CTY05_RS16970	COG0386	Belongs to the glutathione peroxidase family
CTY05_RS17035	COG1121	(ABC) transporter
CTY05_RS17040	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTY05_RS17045	COG1280	lysine exporter protein (LysE YggA)
CTY05_RS17050	COG2837	iron assimilation
CTY05_RS17055	COG0281	malic enzyme
CTY05_RS17100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTY05_RS17100	COG0519	Catalyzes the synthesis of GMP from XMP
CTY05_RS17105	COG4399	Belongs to the UPF0754 family
CTY05_RS17110	COG2259	Doxx family
CTY05_RS17115	COG0586	Pfam SNARE associated Golgi protein
CTY05_RS17130	COG1192	Involved in chromosome partitioning
CTY05_RS17140	COG0271	Belongs to the BolA IbaG family
CTY05_RS17160	COG2267	carboxylic ester hydrolase activity
CTY05_RS17180	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTY05_RS17180	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTY05_RS17180	COG3321	synthase
CTY05_RS17180	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTY05_RS17185	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS17195	COG2197	response regulator
CTY05_RS17205	COG3916	Acyl-homoserine-lactone synthase
CTY05_RS17210	COG0477	Major facilitator Superfamily
CTY05_RS17215	COG1024	Enoyl-CoA hydratase
CTY05_RS17220	COG1024	Enoyl-CoA hydratase
CTY05_RS17225	COG1960	acyl-CoA dehydrogenase activity
CTY05_RS17230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTY05_RS17250	COG1113	amino acid transport
CTY05_RS17255	COG1113	amino acid transport
CTY05_RS17260	COG0251	oxidation-reduction process
CTY05_RS17300	COG0564	pseudouridine synthase activity
CTY05_RS17350	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTY05_RS17365	COG1802	Transcriptional regulator
CTY05_RS17370	COG1448	Aminotransferase
CTY05_RS17375	COG0277	FAD linked oxidase domain protein
CTY05_RS17385	COG2186	Transcriptional regulator
CTY05_RS17395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTY05_RS17410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTY05_RS17420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CTY05_RS17430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTY05_RS17435	COG0438	transferase activity, transferring glycosyl groups
CTY05_RS17450	COG0438	transferase activity, transferring glycosyl groups
CTY05_RS17465	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTY05_RS17495	COG0728	peptidoglycan biosynthetic process
CTY05_RS17500	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTY05_RS17560	COG0546	phosphoglycolate phosphatase activity
CTY05_RS17565	COG1028	Short-chain dehydrogenase reductase Sdr
CTY05_RS17585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTY05_RS17590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTY05_RS17595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTY05_RS17600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTY05_RS17605	COG1116	anion transmembrane transporter activity
CTY05_RS17610	COG1309	transcriptional regulator
CTY05_RS17615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTY05_RS17625	COG0196	riboflavin kinase activity
CTY05_RS17630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTY05_RS17640	COG1047	Peptidyl-prolyl cis-trans
CTY05_RS17680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTY05_RS17685	COG0657	acetylesterase activity
CTY05_RS17735	COG2951	lytic endotransglycosylase activity
CTY05_RS17740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTY05_RS17760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTY05_RS17770	COG0671	phosphoesterase, PA-phosphatase related
CTY05_RS17775	COG0861	Integral membrane protein TerC family
CTY05_RS17785	COG0754	glutathionylspermidine amidase activity
CTY05_RS17795	COG0402	S-adenosylhomocysteine deaminase activity
CTY05_RS17810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTY05_RS17815	COG1230	cation diffusion facilitator family transporter
CTY05_RS17830	COG0706	membrane insertase activity