locus-tag	class	description
IX88_RS00175	COG0626	cystathionine gamma-synthase activity
IX88_RS00180	COG0433	COG0433 Predicted ATPase
IX88_RS00185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_RS00185	COG1017	nitric oxide dioxygenase activity
IX88_RS00190	COG1959	2 iron, 2 sulfur cluster binding
IX88_RS00205	COG1301	dicarboxylic acid transport
IX88_RS00210	COG1946	Acyl-CoA thioesterase
IX88_RS00230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IX88_RS00235	COG1040	competence protein
IX88_RS00240	COG0494	nUDIX hydrolase
IX88_RS00250	COG0598	Magnesium transport protein CorA
IX88_RS00260	COG2854	intermembrane phospholipid transfer
IX88_RS00270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX88_RS00275	COG1127	ABC transporter
IX88_RS00285	COG0513	Belongs to the DEAD box helicase family
IX88_RS00305	COG0408	coproporphyrinogen oxidase activity
IX88_RS00320	COG1960	acyl-CoA dehydrogenase activity
IX88_RS00330	COG1983	PspC domain protein
IX88_RS00335	COG0517	IMP dehydrogenase activity
IX88_RS00375	COG0583	DNA-binding transcription factor activity
IX88_RS00415	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS00425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX88_RS00430	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX88_RS00435	COG0833	amino acid
IX88_RS00465	COG1192	Involved in chromosome partitioning
IX88_RS00470	COG0628	permease
IX88_RS00480	COG1289	transmembrane transporter activity
IX88_RS00495	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_RS00500	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IX88_RS00510	COG0277	FAD linked oxidase domain protein
IX88_RS00515	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IX88_RS00540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IX88_RS00545	COG5380	lipid catabolic process
IX88_RS00565	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IX88_RS00615	COG0194	GDP metabolic process
IX88_RS00625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX88_RS00645	COG3307	-O-antigen
IX88_RS00655	COG4969	Belongs to the N-Me-Phe pilin family
IX88_RS00665	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IX88_RS00670	COG1704	LemA family
IX88_RS00680	COG0493	'glutamate synthase
IX88_RS00685	COG0067	glutamate synthase
IX88_RS00685	COG0069	glutamate synthase activity
IX88_RS00685	COG0070	glutamate synthase
IX88_RS00735	COG2226	methyltransferase
IX88_RS00750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IX88_RS00755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IX88_RS00800	COG0833	amino acid
IX88_RS00865	COG0488	(ABC) transporter
IX88_RS00870	COG2873	o-acetylhomoserine
IX88_RS00875	COG4221	oxidoreductase activity
IX88_RS00880	COG0659	secondary active sulfate transmembrane transporter activity
IX88_RS00900	COG0427	acetyl-CoA hydrolase
IX88_RS00930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IX88_RS00950	COG1132	(ABC) transporter
IX88_RS00975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IX88_RS01040	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_RS01045	COG1733	regulation of RNA biosynthetic process
IX88_RS01085	COG0667	Aldo Keto reductase
IX88_RS01105	COG0583	DNA-binding transcription factor activity
IX88_RS01110	COG2814	Major facilitator Superfamily
IX88_RS01150	COG1335	isochorismatase
IX88_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS01165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IX88_RS01175	COG1113	amino acid transport
IX88_RS01185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX88_RS01200	COG2814	Major facilitator Superfamily
IX88_RS01210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IX88_RS01210	COG0352	thiamine-phosphate diphosphorylase activity
IX88_RS01210	COG0351	phosphomethylpyrimidine kinase
IX88_RS01230	COG1309	transcriptional regulator
IX88_RS01235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IX88_RS01250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_RS01260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX88_RS01265	COG3162	membrane
IX88_RS01270	COG2205	protein histidine kinase activity
IX88_RS01270	COG2198	Histidine kinase
IX88_RS01270	COG0784	Response regulator, receiver
IX88_RS01295	COG1522	sequence-specific DNA binding
IX88_RS01300	COG1335	isochorismatase
IX88_RS01305	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_RS01315	COG0668	transmembrane transport
IX88_RS01320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX88_RS01325	COG1519	Transferase
IX88_RS01330	COG1902	pentaerythritol trinitrate reductase activity
IX88_RS01350	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IX88_RS01375	COG0426	domain, Protein
IX88_RS01375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_RS01380	COG4774	siderophore transport
IX88_RS01385	COG2119	membrane
IX88_RS01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX88_RS01405	COG4942	peptidase
IX88_RS01420	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IX88_RS01430	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IX88_RS01450	COG0189	ligase activity
IX88_RS01470	COG0708	Exodeoxyribonuclease III
IX88_RS01475	COG1393	Belongs to the ArsC family
IX88_RS01490	COG3706	GGDEF domain
IX88_RS01525	COG2351	hydroxyisourate hydrolase activity
IX88_RS01530	COG2233	PERMEase
IX88_RS01540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_RS01550	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IX88_RS01560	COG3150	esterase
IX88_RS01635	COG2918	glutathione biosynthetic process
IX88_RS01650	COG2733	membrane
IX88_RS01655	COG0436	Aminotransferase
IX88_RS01660	COG0534	Mate efflux family protein
IX88_RS01745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IX88_RS01750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IX88_RS01760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IX88_RS01765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX88_RS01770	COG0546	phosphoglycolate phosphatase activity
IX88_RS01780	COG0010	Belongs to the arginase family
IX88_RS01810	COG2188	Transcriptional regulator
IX88_RS01820	COG0523	cobalamin synthesis protein
IX88_RS01830	COG1113	amino acid transport
IX88_RS01840	COG0625	glutathione transferase activity
IX88_RS01860	COG1683	Conserved Protein
IX88_RS01865	COG0534	Mate efflux family protein
IX88_RS01870	COG0385	Bile acid
IX88_RS01875	COG1335	isochorismatase
IX88_RS01880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_RS01900	COG2116	formate transmembrane transporter activity
IX88_RS01905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IX88_RS01910	COG2133	pyrroloquinoline quinone binding
IX88_RS01915	COG2983	Belongs to the UPF0260 family
IX88_RS01935	COG1194	a g-specific adenine glycosylase
IX88_RS01950	COG2818	Glycosylase
IX88_RS01955	COG1064	alcohol dehydrogenase
IX88_RS01960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_RS01970	COG0583	DNA-binding transcription factor activity
IX88_RS01975	COG0656	L-ascorbic acid biosynthetic process
IX88_RS01980	COG2814	Major facilitator Superfamily
IX88_RS02015	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS02030	COG2233	PERMEase
IX88_RS02035	COG0583	DNA-binding transcription factor activity
IX88_RS02070	COG0733	neurotransmitter:sodium symporter activity
IX88_RS02110	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IX88_RS02115	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IX88_RS02120	COG0596	Alpha beta hydrolase
IX88_RS02145	COG0488	(ABC) transporter
IX88_RS02150	COG0586	Pfam SNARE associated Golgi protein
IX88_RS02160	COG0187	DNA topoisomerase II activity
IX88_RS02170	COG0592	DNA-directed DNA polymerase activity
IX88_RS02195	COG0706	membrane insertase activity
IX88_RS02210	COG1230	cation diffusion facilitator family transporter
IX88_RS02215	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_RS02235	COG0402	S-adenosylhomocysteine deaminase activity
IX88_RS02245	COG0754	glutathionylspermidine amidase activity
IX88_RS02255	COG0861	Integral membrane protein TerC family
IX88_RS02260	COG0671	phosphoesterase, PA-phosphatase related
IX88_RS02270	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX88_RS02285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IX88_RS02290	COG2951	lytic endotransglycosylase activity
IX88_RS02320	COG0583	DNA-binding transcription factor activity
IX88_RS02340	COG0657	acetylesterase activity
IX88_RS02345	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX88_RS02385	COG1047	Peptidyl-prolyl cis-trans
IX88_RS02395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IX88_RS02400	COG0196	riboflavin kinase activity
IX88_RS02410	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IX88_RS02415	COG1309	transcriptional regulator
IX88_RS02420	COG1116	anion transmembrane transporter activity
IX88_RS02425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_RS02430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IX88_RS02435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_RS02440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS02465	COG0546	phosphoglycolate phosphatase activity
IX88_RS02520	COG3023	N-Acetylmuramoyl-L-alanine amidase
IX88_RS02525	COG0728	peptidoglycan biosynthetic process
IX88_RS02555	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX88_RS02565	COG1215	transferase activity, transferring glycosyl groups
IX88_RS02570	COG0438	transferase activity, transferring glycosyl groups
IX88_RS02580	COG0438	transferase activity, transferring glycosyl groups
IX88_RS02590	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IX88_RS02595	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IX88_RS02610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX88_RS02620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_RS02630	COG2186	Transcriptional regulator
IX88_RS02640	COG0277	FAD linked oxidase domain protein
IX88_RS02645	COG1448	Aminotransferase
IX88_RS02650	COG1802	Transcriptional regulator
IX88_RS02665	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IX88_RS02715	COG0564	pseudouridine synthase activity
IX88_RS02755	COG0251	oxidation-reduction process
IX88_RS02760	COG1113	amino acid transport
IX88_RS02765	COG1113	amino acid transport
IX88_RS02785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_RS02790	COG1960	acyl-CoA dehydrogenase activity
IX88_RS02795	COG1024	Enoyl-CoA hydratase
IX88_RS02800	COG1024	Enoyl-CoA hydratase
IX88_RS02805	COG0477	Major facilitator Superfamily
IX88_RS02810	COG3916	Acyl-homoserine-lactone synthase
IX88_RS02820	COG2197	response regulator
IX88_RS02830	COG1960	acyl-CoA dehydrogenase activity
IX88_RS02835	COG3321	synthase
IX88_RS02835	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IX88_RS02835	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX88_RS02835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IX88_RS02875	COG0271	Belongs to the BolA IbaG family
IX88_RS02885	COG1192	Involved in chromosome partitioning
IX88_RS02900	COG0586	Pfam SNARE associated Golgi protein
IX88_RS02905	COG2259	Doxx family
IX88_RS02910	COG4399	Belongs to the UPF0754 family
IX88_RS02915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IX88_RS02915	COG0519	Catalyzes the synthesis of GMP from XMP
IX88_RS02960	COG0281	malic enzyme
IX88_RS02965	COG2837	iron assimilation
IX88_RS02970	COG1280	lysine exporter protein (LysE YggA)
IX88_RS02975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IX88_RS02980	COG1121	(ABC) transporter
IX88_RS03045	COG0386	Belongs to the glutathione peroxidase family
IX88_RS03060	COG1309	transcriptional regulator
IX88_RS03065	COG0697	spore germination
IX88_RS03075	COG0758	DNA mediated transformation
IX88_RS03110	COG1309	transcriptional regulator
IX88_RS03145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IX88_RS03155	COG0655	NAD(P)H dehydrogenase (quinone) activity
IX88_RS03190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX88_RS03200	COG0477	Major facilitator Superfamily
IX88_RS03210	COG1253	flavin adenine dinucleotide binding
IX88_RS03220	COG2860	membrane
IX88_RS03225	COG0477	Major facilitator Superfamily
IX88_RS03235	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_RS03250	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IX88_RS03265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_RS03275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_RS03280	COG0606	chelatase, subunit chli
IX88_RS03290	COG0347	Belongs to the P(II) protein family
IX88_RS03295	COG0004	ammonium transporteR
IX88_RS03305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX88_RS03305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX88_RS03345	COG0795	lipopolysaccharide-transporting ATPase activity
IX88_RS03350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IX88_RS03355	COG0793	Belongs to the peptidase S41A family
IX88_RS03370	COG2197	response regulator
IX88_RS03380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IX88_RS03390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_RS03395	COG4974	Belongs to the 'phage' integrase family
IX88_RS03420	COG0772	Belongs to the SEDS family
IX88_RS03425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IX88_RS03430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IX88_RS03435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IX88_RS03460	COG0697	spore germination
IX88_RS03465	COG1538	Outer membrane efflux protein
IX88_RS03485	COG3275	phosphorelay sensor kinase activity
IX88_RS03495	COG0181	hydroxymethylbilane synthase activity
IX88_RS03540	COG1716	ATPase activity
IX88_RS03545	COG0546	phosphoglycolate phosphatase activity
IX88_RS03695	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_RS03715	COG0596	Alpha beta hydrolase
IX88_RS03720	COG2056	Na+-H+ antiporter family
IX88_RS03735	COG0326	Molecular chaperone. Has ATPase activity
IX88_RS03750	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IX88_RS03805	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IX88_RS03810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IX88_RS03810	COG2169	Transcriptional regulator
IX88_RS03840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IX88_RS03850	COG0497	DNA recombination
IX88_RS03865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX88_RS03875	COG0237	dephospho-CoA kinase activity
IX88_RS03925	COG0195	Participates in both transcription termination and antitermination
IX88_RS03940	COG1320	monovalent cation:proton antiporter activity
IX88_RS03945	COG2212	antiporter activity
IX88_RS03950	COG1863	multisubunit Na H antiporter MnhE subunit
IX88_RS03955	COG0651	ATP synthesis coupled electron transport
IX88_RS03960	COG1006	Multisubunit Na H antiporter MnhC subunit
IX88_RS03965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IX88_RS03965	COG2111	Na H antiporter
IX88_RS03980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IX88_RS03985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_RS04000	COG2226	methyltransferase
IX88_RS04020	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IX88_RS04025	COG1074	ATP-dependent DNA helicase activity
IX88_RS04030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX88_RS04035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IX88_RS04050	COG0598	Magnesium transport protein CorA
IX88_RS04055	COG0789	Transcriptional regulator
IX88_RS04060	COG0484	heat shock protein binding
IX88_RS04075	COG0475	glutathione-regulated potassium exporter activity
IX88_RS04075	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_RS04080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IX88_RS04100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_RS04110	COG4535	Mg2 and Co2 transporter CorC
IX88_RS04115	COG0425	Belongs to the sulfur carrier protein TusA family
IX88_RS04125	COG0644	oxidoreductase
IX88_RS04125	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IX88_RS04135	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IX88_RS04150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_RS04155	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IX88_RS04165	COG0493	'glutamate synthase
IX88_RS04165	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX88_RS04190	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IX88_RS04205	COG0534	Mate efflux family protein
IX88_RS04215	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX88_RS04220	COG4221	oxidoreductase activity
IX88_RS04225	COG0583	DNA-binding transcription factor activity
IX88_RS04240	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_RS04245	COG1530	ribonuclease E activity
IX88_RS04255	COG0546	phosphoglycolate phosphatase activity
IX88_RS04260	COG2378	regulation of single-species biofilm formation
IX88_RS04265	COG0625	glutathione transferase activity
IX88_RS04275	COG0583	DNA-binding transcription factor activity
IX88_RS04330	COG0473	3-isopropylmalate dehydrogenase activity
IX88_RS04385	COG1301	dicarboxylic acid transport
IX88_RS04395	COG1560	Kdo2-lipid A biosynthetic process
IX88_RS04400	COG1280	lysine exporter protein (LysE YggA)
IX88_RS04410	COG0488	(ABC) transporter
IX88_RS04415	COG2900	Belongs to the SlyX family
IX88_RS04425	COG1733	regulation of RNA biosynthetic process
IX88_RS04450	COG0210	DNA helicase
IX88_RS04455	COG0724	RNA recognition motif
IX88_RS04475	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_RS04475	COG4651	solute:proton antiporter activity
IX88_RS04500	COG0788	formyltetrahydrofolate deformylase activity
IX88_RS04600	COG2813	Specifically methylates the guanine in position
IX88_RS04600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_RS04610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX88_RS04620	COG4774	siderophore transport
IX88_RS04630	COG0740	serine-type endopeptidase activity
IX88_RS04650	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IX88_RS04650	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IX88_RS04655	COG0280	phosphate acetyltransferase
IX88_RS04655	COG0857	belongs to the CobB CobQ family
IX88_RS04660	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX88_RS04670	COG0800	Aldolase
IX88_RS04680	COG3265	gluconokinase activity
IX88_RS04685	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS04695	COG2267	carboxylic ester hydrolase activity
IX88_RS04710	COG0793	Belongs to the peptidase S41A family
IX88_RS04745	COG1426	Protein conserved in bacteria
IX88_RS04785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX88_RS04795	COG1162	GTPase activity
IX88_RS04800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IX88_RS04815	COG1538	Outer membrane efflux protein
IX88_RS04820	COG0577	efflux transmembrane transporter activity
IX88_RS04820	COG1136	(ABC) transporter
IX88_RS04825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS04850	COG0028	Belongs to the TPP enzyme family
IX88_RS04855	COG0440	acetolactate synthase activity
IX88_RS04895	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IX88_RS04910	COG0084	hydrolase, TatD family'
IX88_RS04925	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IX88_RS04930	COG0583	DNA-binding transcription factor activity
IX88_RS04940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX88_RS04955	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IX88_RS04965	COG2814	Major facilitator Superfamily
IX88_RS04975	COG0697	spore germination
IX88_RS05005	COG3622	Belongs to the hyi family
IX88_RS05010	COG2084	Dehydrogenase
IX88_RS05015	COG1024	Enoyl-CoA hydratase
IX88_RS05020	COG2205	protein histidine kinase activity
IX88_RS05020	COG5002	protein histidine kinase activity
IX88_RS05020	COG0784	Response regulator, receiver
IX88_RS05040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX88_RS05050	COG3956	TIGRFAM MazG family protein
IX88_RS05055	COG1555	photosystem II stabilization
IX88_RS05060	COG0617	tRNA 3'-terminal CCA addition
IX88_RS05065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX88_RS05085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX88_RS05090	COG3028	Belongs to the UPF0307 family
IX88_RS05095	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_RS05110	COG0625	glutathione transferase activity
IX88_RS05115	COG1238	metal cluster binding
IX88_RS05155	COG0072	phenylalanine-tRNA ligase activity
IX88_RS05180	COG0248	Ppx GppA phosphatase
IX88_RS05190	COG0037	tRNA processing
IX88_RS05230	COG1764	response to oxidative stress
IX88_RS05235	COG1846	Transcriptional regulator
IX88_RS05245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX88_RS05305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IX88_RS05310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IX88_RS05315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX88_RS05390	COG1214	PFAM Peptidase M22, glycoprotease
IX88_RS05415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IX88_RS05420	COG0561	phosphatase activity
IX88_RS05430	COG2132	Multicopper oxidase
IX88_RS05450	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IX88_RS05455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IX88_RS05460	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IX88_RS05490	COG1063	alcohol dehydrogenase
IX88_RS05495	COG0583	DNA-binding transcription factor activity
IX88_RS05500	COG1960	acyl-CoA dehydrogenase activity
IX88_RS05505	COG2814	Major facilitator Superfamily
IX88_RS05510	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IX88_RS05515	COG1309	transcriptional regulator
IX88_RS05530	COG1053	succinate dehydrogenase
IX88_RS05535	COG0583	DNA-binding transcription factor activity
IX88_RS05550	COG0583	DNA-binding transcription factor activity
IX88_RS05560	COG0583	DNA-binding transcription factor activity
IX88_RS05575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_RS05625	COG0384	phenazine biosynthesis protein PhzF
IX88_RS05635	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX88_RS05655	COG0745	RESPONSE REGULATOR receiver
IX88_RS05695	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IX88_RS05725	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IX88_RS05730	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX88_RS05755	COG0583	DNA-binding transcription factor activity
IX88_RS05775	COG0668	transmembrane transport
IX88_RS05785	COG2081	HI0933 family
IX88_RS05790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IX88_RS05820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_RS05820	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX88_RS05830	COG0489	protein tyrosine kinase activity
IX88_RS05880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX88_RS05890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IX88_RS05905	COG0730	response to heat
IX88_RS05915	COG1196	nuclear chromosome segregation
IX88_RS05935	COG2223	nitrite transmembrane transporter activity
IX88_RS05940	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IX88_RS05945	COG1877	trehalose-phosphatase activity
IX88_RS05950	COG0596	Alpha beta hydrolase
IX88_RS05950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_RS05950	COG2226	methyltransferase
IX88_RS05965	COG4106	trans-aconitate 2-methyltransferase activity
IX88_RS05980	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IX88_RS05985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IX88_RS05990	COG0009	L-threonylcarbamoyladenylate synthase
IX88_RS05995	COG3101	peptidyl-lysine hydroxylation
IX88_RS06000	COG1399	metal-binding, possibly nucleic acid-binding protein
IX88_RS06025	COG1652	LysM domain
IX88_RS06030	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IX88_RS06030	COG0352	thiamine-phosphate diphosphorylase activity
IX88_RS06030	COG0351	phosphomethylpyrimidine kinase
IX88_RS06040	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IX88_RS06070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX88_RS06100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IX88_RS06115	COG0358	DNA primase activity
IX88_RS06125	COG0564	pseudouridine synthase activity
IX88_RS06150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX88_RS06165	COG0583	DNA-binding transcription factor activity
IX88_RS06170	COG0473	3-isopropylmalate dehydrogenase activity
IX88_RS06180	COG0657	acetylesterase activity
IX88_RS06190	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS06210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IX88_RS06210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX88_RS06225	COG1981	membrane
IX88_RS06270	COG0456	acetyltransferase
IX88_RS06280	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IX88_RS06285	COG0492	ferredoxin-NADP+ reductase activity
IX88_RS06290	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IX88_RS06290	COG1674	ftsk spoiiie
IX88_RS06295	COG1280	lysine exporter protein (LysE YggA)
IX88_RS06310	COG2894	cell division
IX88_RS06325	COG0204	Acyl-transferase
IX88_RS06330	COG2885	chlorophyll binding
IX88_RS06335	COG0210	DNA helicase
IX88_RS06345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX88_RS06360	COG0121	glutamine amidotransferase
IX88_RS06380	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX88_RS06385	COG0735	belongs to the Fur family
IX88_RS06410	COG0420	3'-5' exonuclease activity
IX88_RS06430	COG1090	epimerase
IX88_RS06445	COG2050	protein possibly involved in aromatic compounds catabolism
IX88_RS06455	COG2814	Major facilitator Superfamily
IX88_RS06460	COG0405	Gamma-glutamyltransferase
IX88_RS06465	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IX88_RS06485	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
IX88_RS06515	COG0477	Major facilitator Superfamily
IX88_RS06520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX88_RS06550	COG0531	amino acid
IX88_RS06555	COG2040	homocysteine
IX88_RS06580	COG1309	transcriptional regulator
IX88_RS06585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_RS06590	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX88_RS06600	COG1607	acyl-coa hydrolase
IX88_RS06610	COG0523	cobalamin synthesis protein
IX88_RS06620	COG4681	YaeQ
IX88_RS06630	COG0726	polysaccharide deacetylase
IX88_RS06630	COG1649	PFAM Uncharacterised BCR, COG1649
IX88_RS06635	COG1215	transferase activity, transferring glycosyl groups
IX88_RS06645	COG1024	Enoyl-CoA hydratase
IX88_RS06660	COG1414	Transcriptional regulator
IX88_RS06680	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS06695	COG2271	Major facilitator Superfamily
IX88_RS06705	COG2267	carboxylic ester hydrolase activity
IX88_RS06710	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS06725	COG0028	Belongs to the TPP enzyme family
IX88_RS06735	COG0477	Major facilitator Superfamily
IX88_RS06740	COG0242	peptide deformylase activity
IX88_RS06745	COG2066	Belongs to the glutaminase family
IX88_RS06750	COG2207	Transcriptional regulator
IX88_RS06755	COG2223	nitrite transmembrane transporter activity
IX88_RS06770	COG0583	DNA-binding transcription factor activity
IX88_RS06775	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS06780	COG2271	Major facilitator Superfamily
IX88_RS06785	COG3959	Transketolase, thiamine diphosphate binding domain
IX88_RS06790	COG3958	Transketolase
IX88_RS06805	COG0306	phosphate transporter
IX88_RS06825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IX88_RS06870	COG4181	ATPase activity
IX88_RS06875	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IX88_RS06900	COG0583	DNA-binding transcription factor activity
IX88_RS06910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_RS06915	COG1773	rubredoxin
IX88_RS06960	COG2851	Citrate transporter
IX88_RS06965	COG1253	flavin adenine dinucleotide binding
IX88_RS07005	COG0804	urea catabolic process
IX88_RS07015	COG0830	nickel cation binding
IX88_RS07030	COG0742	ribosomal rna small subunit methyltransferase
IX88_RS07035	COG0768	penicillin binding
IX88_RS07055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IX88_RS07060	COG2878	Part of a membrane complex involved in electron transport
IX88_RS07065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX88_RS07075	COG3384	dioxygenase
IX88_RS07110	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IX88_RS07140	COG0006	proline dipeptidase activity
IX88_RS07145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_RS07150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_RS07170	COG1279	arginine transmembrane transporter activity
IX88_RS07175	COG0583	DNA-binding transcription factor activity
IX88_RS07215	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX88_RS07220	COG0741	lytic transglycosylase activity
IX88_RS07220	COG1388	LysM domain
IX88_RS07220	COG0741	lytic transglycosylase activity
IX88_RS07220	COG1388	LysM domain
IX88_RS07225	COG4166	transmembrane transport
IX88_RS07230	COG4174	ABC transporter (Permease)
IX88_RS07235	COG4239	(ABC) transporter, permease
IX88_RS07240	COG4172	Belongs to the ABC transporter superfamily
IX88_RS07270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX88_RS07280	COG2203	Gaf domain
IX88_RS07280	COG3706	GGDEF domain
IX88_RS07280	COG4251	negative regulation of phosphorylation
IX88_RS07280	COG5001	Diguanylate cyclase
IX88_RS07290	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_RS07290	COG1902	pentaerythritol trinitrate reductase activity
IX88_RS07300	COG0582	viral genome integration into host DNA
IX88_RS07330	COG3328	transposase activity
IX88_RS07380	COG0789	Transcriptional regulator
IX88_RS07435	COG2184	nucleotidyltransferase activity
IX88_RS07440	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IX88_RS07445	COG0732	type I restriction modification DNA specificity domain
IX88_RS07465	COG1309	transcriptional regulator
IX88_RS07500	COG3209	COG3209 Rhs family protein
IX88_RS07550	COG1113	amino acid transport
IX88_RS07560	COG0531	amino acid
IX88_RS07580	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS07600	COG1113	amino acid transport
IX88_RS07615	COG0697	spore germination
IX88_RS07620	COG2721	sulfolactate sulfo-lyase activity
IX88_RS07625	COG2271	Major facilitator Superfamily
IX88_RS07630	COG4948	Mandelate Racemase Muconate Lactonizing
IX88_RS07640	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS07645	COG2186	Transcriptional regulator
IX88_RS07670	COG1960	acyl-CoA dehydrogenase activity
IX88_RS07680	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS07685	COG1024	Enoyl-CoA hydratase
IX88_RS07690	COG2814	Major facilitator Superfamily
IX88_RS07705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_RS07750	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IX88_RS07755	COG2072	flavoprotein involved in K transport
IX88_RS07760	COG0300	oxidoreductase activity
IX88_RS07770	COG1309	transcriptional regulator
IX88_RS07775	COG1741	Belongs to the pirin family
IX88_RS07790	COG2072	flavoprotein involved in K transport
IX88_RS07800	COG2252	PERMEase
IX88_RS07805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX88_RS07810	COG3038	cytochrome b561
IX88_RS07820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IX88_RS07830	COG0527	aspartate kinase activity
IX88_RS07840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX88_RS07850	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IX88_RS07865	COG0667	Aldo Keto reductase
IX88_RS07875	COG1765	OsmC-like protein
IX88_RS07890	COG0542	response to heat
IX88_RS07925	COG2885	chlorophyll binding
IX88_RS07935	COG0625	glutathione transferase activity
IX88_RS07940	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IX88_RS07960	COG3634	alkyl hydroperoxide reductase activity
IX88_RS07970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IX88_RS07980	COG0450	alkyl hydroperoxide reductase
IX88_RS07985	COG1643	Atp-dependent helicase
IX88_RS08000	COG2814	Major facilitator Superfamily
IX88_RS08005	COG3135	benzoate transporter
IX88_RS08010	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS08015	COG0543	2 iron, 2 sulfur cluster binding
IX88_RS08015	COG0633	Ferredoxin
IX88_RS08020	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IX88_RS08025	COG4638	Rieske (2fe-2S)
IX88_RS08030	COG0583	DNA-binding transcription factor activity
IX88_RS08080	COG1570	exodeoxyribonuclease VII activity
IX88_RS08115	COG1280	lysine exporter protein (LysE YggA)
IX88_RS08120	COG1278	Cold shock
IX88_RS08150	COG2814	Major facilitator Superfamily
IX88_RS08200	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IX88_RS08210	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IX88_RS08215	COG1137	ATPase activity
IX88_RS08220	COG1538	Outer membrane efflux protein
IX88_RS08250	COG4122	O-methyltransferase activity
IX88_RS08260	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IX88_RS08275	COG1522	sequence-specific DNA binding
IX88_RS08280	COG5006	permease, DMT superfamily
IX88_RS08290	COG1560	Kdo2-lipid A biosynthetic process
IX88_RS08300	COG2814	Major facilitator Superfamily
IX88_RS08320	COG1250	3-hydroxyacyl-CoA dehydrogenase
IX88_RS08370	COG0583	DNA-binding transcription factor activity
IX88_RS08375	COG1914	H( )-stimulated, divalent metal cation uptake system
IX88_RS08395	COG4770	biotin carboxylase activity
IX88_RS08400	COG0038	chloride channel
IX88_RS08405	COG2831	hemolysin activation secretion protein
IX88_RS08410	COG3210	domain, Protein
IX88_RS08455	COG2207	Transcriptional regulator
IX88_RS08470	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IX88_RS08475	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX88_RS08480	COG2271	Major facilitator Superfamily
IX88_RS08485	COG0753	catalase activity
IX88_RS08490	COG3038	cytochrome b561
IX88_RS08495	COG0583	DNA-binding transcription factor activity
IX88_RS08505	COG1414	Transcriptional regulator
IX88_RS08510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX88_RS08520	COG1840	ABC-type Fe3 transport system, periplasmic component
IX88_RS08525	COG3842	ATPase activity
IX88_RS08540	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IX88_RS08545	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX88_RS08550	COG2814	Major facilitator Superfamily
IX88_RS08555	COG1960	acyl-CoA dehydrogenase activity
IX88_RS08570	COG1024	Enoyl-CoA hydratase
IX88_RS08580	COG2814	Major facilitator Superfamily
IX88_RS08590	COG0183	Belongs to the thiolase family
IX88_RS08595	COG1250	3-hydroxyacyl-CoA dehydrogenase
IX88_RS08600	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS08605	COG1024	Enoyl-CoA hydratase
IX88_RS08610	COG1960	acyl-CoA dehydrogenase activity
IX88_RS08615	COG2814	Major facilitator Superfamily
IX88_RS08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_RS08625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_RS08635	COG2814	Major facilitator Superfamily
IX88_RS08645	COG1960	acyl-CoA dehydrogenase activity
IX88_RS08660	COG0583	DNA-binding transcription factor activity
IX88_RS08670	COG4770	biotin carboxylase activity
IX88_RS08675	COG1024	Enoyl-CoA hydratase
IX88_RS08680	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IX88_RS08685	COG1960	acyl-CoA dehydrogenase activity
IX88_RS08690	COG1309	transcriptional regulator
IX88_RS08695	COG0318	PFAM AMP-dependent synthetase and ligase
IX88_RS08715	COG0583	DNA-binding transcription factor activity
IX88_RS08765	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS08785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX88_RS08805	COG2205	protein histidine kinase activity
IX88_RS08805	COG0784	Response regulator, receiver
IX88_RS08820	COG0765	amino acid transport
IX88_RS08825	COG0765	amino acid transport
IX88_RS08830	COG1126	abc transporter atp-binding protein
IX88_RS08835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX88_RS08840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX88_RS08850	COG1280	lysine exporter protein (LysE YggA)
IX88_RS08855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IX88_RS08860	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX88_RS08865	COG1045	serine acetyltransferase
IX88_RS08880	COG0583	DNA-binding transcription factor activity
IX88_RS08885	COG0625	glutathione transferase activity
IX88_RS08890	COG0625	glutathione transferase activity
IX88_RS08895	COG0583	DNA-binding transcription factor activity
IX88_RS08905	COG1346	cytolysis
IX88_RS08925	COG2814	Major facilitator Superfamily
IX88_RS08935	COG0583	DNA-binding transcription factor activity
IX88_RS08945	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
IX88_RS08950	COG3052	prosthetic group binding
IX88_RS08970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IX88_RS08990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_RS09000	COG1294	oxidase, subunit
IX88_RS09005	COG1271	oxidase subunit
IX88_RS09025	COG0477	Major facilitator Superfamily
IX88_RS09035	COG4521	taurine ABC transporter
IX88_RS09040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IX88_RS09045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_RS09050	COG2175	clavaminate synthase activity
IX88_RS09060	COG1953	Uracil, thiamine, allantoin
IX88_RS09070	COG0583	DNA-binding transcription factor activity
IX88_RS09080	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IX88_RS09095	COG0640	Transcriptional regulator
IX88_RS09100	COG0798	PFAM Bile acid sodium symporter
IX88_RS09105	COG0583	DNA-binding transcription factor activity
IX88_RS09120	COG3634	alkyl hydroperoxide reductase activity
IX88_RS09160	COG0436	Aminotransferase
IX88_RS09170	COG0386	Belongs to the glutathione peroxidase family
IX88_RS09210	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IX88_RS09235	COG0012	GTP binding
IX88_RS09240	COG2011	ABC-type metal ion transport system permease component
IX88_RS09245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX88_RS09255	COG1464	Belongs to the NlpA lipoprotein family
IX88_RS09285	COG0765	amino acid transport
IX88_RS09290	COG0765	amino acid transport
IX88_RS09295	COG1126	abc transporter atp-binding protein
IX88_RS09305	COG1522	sequence-specific DNA binding
IX88_RS09320	COG1309	transcriptional regulator
IX88_RS09355	COG0583	DNA-binding transcription factor activity
IX88_RS09365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IX88_RS09375	COG0697	spore germination
IX88_RS09400	COG3121	Chaperone
IX88_RS09405	COG3539	Fimbrial protein
IX88_RS09430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IX88_RS09430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IX88_RS09475	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX88_RS09485	COG2353	YceI-like domain
IX88_RS09495	COG3698	Phosphodiester glycosidase
IX88_RS09510	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IX88_RS09515	COG0506	proline dehydrogenase activity
IX88_RS09515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IX88_RS09515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IX88_RS09525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX88_RS09530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IX88_RS09550	COG1132	(ABC) transporter
IX88_RS09555	COG3122	Protein conserved in bacteria
IX88_RS09560	COG3619	membrane
IX88_RS09570	COG0640	Transcriptional regulator
IX88_RS09580	COG2850	peptidyl-arginine hydroxylation
IX88_RS09585	COG0424	maF-like protein
IX88_RS09605	COG0191	fructose-bisphosphate aldolase activity
IX88_RS09610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX88_RS09625	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IX88_RS09635	COG1192	Involved in chromosome partitioning
IX88_RS09640	COG1475	DNA binding
IX88_RS09645	COG0811	peptide transport
IX88_RS09655	COG1132	(ABC) transporter
IX88_RS09660	COG1663	tetraacyldisaccharide 4'-kinase activity
IX88_RS09680	COG0084	hydrolase, TatD family'
IX88_RS09745	COG0776	regulation of translation
IX88_RS09775	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IX88_RS09780	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IX88_RS09820	COG0339	signal peptide processing
IX88_RS09825	COG0601	transmembrane transport
IX88_RS09830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX88_RS09865	COG0702	epimerase
IX88_RS09870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX88_RS09890	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IX88_RS09920	COG0316	Belongs to the HesB IscA family
IX88_RS09925	COG0822	iron-sulfur transferase activity
IX88_RS09950	COG0776	regulation of translation
IX88_RS09955	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX88_RS09960	COG2207	Transcriptional regulator
IX88_RS09965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX88_RS09970	COG1960	acyl-CoA dehydrogenase activity
IX88_RS09975	COG1960	acyl-CoA dehydrogenase activity
IX88_RS09990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IX88_RS10005	COG2814	Major facilitator Superfamily
IX88_RS10010	COG4264	IucA IucC family
IX88_RS10015	COG4264	IucA IucC family
IX88_RS10025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IX88_RS10055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IX88_RS10070	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
IX88_RS10075	COG0406	alpha-ribazole phosphatase activity
IX88_RS10090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX88_RS10095	COG0730	response to heat
IX88_RS10115	COG4773	Receptor
IX88_RS10120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX88_RS10135	COG1131	(ABC) transporter
IX88_RS10140	COG0842	Transport permease protein
IX88_RS10145	COG0842	Transport permease protein
IX88_RS10200	COG2226	methyltransferase
IX88_RS10225	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IX88_RS10260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX88_RS10270	COG0133	tryptophan synthase activity
IX88_RS10285	COG3706	GGDEF domain
IX88_RS10300	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX88_RS10305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IX88_RS10310	COG0022	dehydrogenase e1 component
IX88_RS10315	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX88_RS10320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_RS10330	COG1063	alcohol dehydrogenase
IX88_RS10335	COG3781	membrane
IX88_RS10345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_RS10345	COG3453	Protein conserved in bacteria
IX88_RS10355	COG0730	response to heat
IX88_RS10370	COG2207	Transcriptional regulator
IX88_RS10370	COG3708	Transcriptional regulator
IX88_RS10375	COG1733	regulation of RNA biosynthetic process
IX88_RS10380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IX88_RS10390	COG2188	Transcriptional regulator
IX88_RS10405	COG4521	taurine ABC transporter
IX88_RS10410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_RS10415	COG0477	Major facilitator Superfamily
IX88_RS10425	COG1027	Aspartate ammonia-lyase
IX88_RS10440	COG0583	DNA-binding transcription factor activity
IX88_RS10445	COG0583	DNA-binding transcription factor activity
IX88_RS10450	COG0183	Belongs to the thiolase family
IX88_RS10455	COG2031	fatty acid transporter
IX88_RS10470	COG0583	DNA-binding transcription factor activity
IX88_RS10490	COG1309	transcriptional regulator
IX88_RS10500	COG2610	gluconate transmembrane transporter activity
IX88_RS10505	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS10510	COG2207	Transcriptional regulator
IX88_RS10525	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS10535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_RS10550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_RS10550	COG0543	2 iron, 2 sulfur cluster binding
IX88_RS10555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IX88_RS10560	COG4638	Rieske (2fe-2S)
IX88_RS10570	COG0725	ABC transporter, periplasmic molybdate-binding protein
IX88_RS10575	COG4149	molybdate abc transporter
IX88_RS10580	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IX88_RS10585	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS10590	COG3433	isochorismatase activity
IX88_RS10590	COG1535	isochorismatase
IX88_RS10650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX88_RS10665	COG0753	catalase activity
IX88_RS10675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IX88_RS10700	COG3539	Fimbrial protein
IX88_RS10770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX88_RS10775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS10780	COG0745	RESPONSE REGULATOR receiver
IX88_RS10795	COG2205	protein histidine kinase activity
IX88_RS10805	COG2207	Transcriptional regulator
IX88_RS10820	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS10870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IX88_RS10920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX88_RS10940	COG1120	ATPase activity
IX88_RS10945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX88_RS10955	COG1064	alcohol dehydrogenase
IX88_RS10970	COG2207	Transcriptional regulator
IX88_RS10975	COG2084	Dehydrogenase
IX88_RS10985	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IX88_RS10990	COG0583	DNA-binding transcription factor activity
IX88_RS11000	COG0129	dihydroxy-acid dehydratase activity
IX88_RS11005	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS11045	COG0583	DNA-binding transcription factor activity
IX88_RS11060	COG2188	Transcriptional regulator
IX88_RS11090	COG3210	domain, Protein
IX88_RS11095	COG2831	hemolysin activation secretion protein
IX88_RS11105	COG1473	amidohydrolase
IX88_RS11115	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX88_RS11115	COG0475	glutathione-regulated potassium exporter activity
IX88_RS11125	COG0583	DNA-binding transcription factor activity
IX88_RS11130	COG1335	isochorismatase
IX88_RS11140	COG1309	transcriptional regulator
IX88_RS11180	COG1902	pentaerythritol trinitrate reductase activity
IX88_RS11180	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_RS11195	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS11215	COG2186	Transcriptional regulator
IX88_RS11225	COG0583	DNA-binding transcription factor activity
IX88_RS11230	COG4948	Mandelate Racemase Muconate Lactonizing
IX88_RS11235	COG4829	muconolactone delta-isomerase
IX88_RS11245	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_RS11250	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_RS11255	COG0183	Belongs to the thiolase family
IX88_RS11260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IX88_RS11270	COG1012	belongs to the aldehyde dehydrogenase family
IX88_RS11280	COG3733	amine oxidase
IX88_RS11290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_RS11300	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS11310	COG4638	Rieske (2fe-2S)
IX88_RS11330	COG0154	amidase activity
IX88_RS11340	COG2814	Major facilitator Superfamily
IX88_RS11365	COG1960	acyl-CoA dehydrogenase activity
IX88_RS11370	COG0583	DNA-binding transcription factor activity
IX88_RS11375	COG1414	Transcriptional regulator
IX88_RS11390	COG2391	methyltransferase activity
IX88_RS11400	COG4993	Dehydrogenase
IX88_RS11405	COG3659	wide pore channel activity
IX88_RS11410	COG3420	alginic acid biosynthetic process
IX88_RS11415	COG0710	3-dehydroquinate dehydratase activity
IX88_RS11420	COG3485	protocatechuate 3,4-dioxygenase
IX88_RS11425	COG3485	protocatechuate 3,4-dioxygenase
IX88_RS11430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IX88_RS11435	COG2271	Major facilitator Superfamily
IX88_RS11440	COG0596	Alpha beta hydrolase
IX88_RS11445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IX88_RS11450	COG0183	Belongs to the thiolase family
IX88_RS11455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IX88_RS11460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IX88_RS11470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IX88_RS11475	COG2323	membrane
IX88_RS11520	COG1902	pentaerythritol trinitrate reductase activity
IX88_RS11520	COG0446	pyridine nucleotide-disulphide oxidoreductase
IX88_RS11545	COG0542	response to heat
IX88_RS11550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IX88_RS11580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IX88_RS11585	COG0569	domain protein
IX88_RS11590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IX88_RS11610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IX88_RS11620	COG1585	Membrane protein implicated in regulation of membrane protease activity
IX88_RS11635	COG1294	oxidase, subunit
IX88_RS11640	COG4890	Cyd operon protein YbgT
IX88_RS11655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IX88_RS11665	COG0552	protein localization to endoplasmic reticulum
IX88_RS11690	COG0516	GMP reductase activity
IX88_RS11690	COG0517	IMP dehydrogenase activity
IX88_RS11695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX88_RS11700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IX88_RS11710	COG0583	DNA-binding transcription factor activity
IX88_RS11715	COG0024	Methionine aminopeptidase
IX88_RS11745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX88_RS11745	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX88_RS11750	COG1105	Belongs to the carbohydrate kinase PfkB family
IX88_RS11755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX88_RS11755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IX88_RS11755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IX88_RS11770	COG5001	Diguanylate cyclase
IX88_RS11770	COG3300	MHYT domain
IX88_RS11785	COG2135	peptidase activity
IX88_RS11790	COG0659	secondary active sulfate transmembrane transporter activity
IX88_RS11805	COG1113	amino acid transport
IX88_RS11815	COG1522	sequence-specific DNA binding
IX88_RS11840	COG1011	Hydrolase
IX88_RS11845	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IX88_RS11855	COG2137	regulation of response to DNA damage stimulus
IX88_RS11870	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX88_RS11890	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX88_RS11905	COG0575	Belongs to the CDS family
IX88_RS11910	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IX88_RS11930	COG3852	Histidine kinase
IX88_RS11935	COG2204	response regulator
IX88_RS11990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IX88_RS11995	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IX88_RS12015	COG0697	spore germination
IX88_RS12020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_RS12030	COG0303	'Molybdopterin
IX88_RS12035	COG0315	cyclic pyranopterin monophosphate synthase activity
IX88_RS12035	COG0521	Mo-molybdopterin cofactor biosynthetic process
IX88_RS12050	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IX88_RS12055	COG0243	molybdopterin cofactor binding
IX88_RS12065	COG0243	molybdopterin cofactor binding
IX88_RS12070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_RS12075	COG2146	nitrite reductase [NAD(P)H] activity
IX88_RS12075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_RS12085	COG0745	RESPONSE REGULATOR receiver
IX88_RS12090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_RS12090	COG1116	anion transmembrane transporter activity
IX88_RS12105	COG0511	ligase activity, forming carbon-carbon bonds
IX88_RS12120	COG2814	Major facilitator Superfamily
IX88_RS12150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IX88_RS12250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IX88_RS12535	COG0069	glutamate synthase activity
IX88_RS12555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IX88_RS12565	COG1454	alcohol dehydrogenase
IX88_RS12570	COG0824	Thioesterase
IX88_RS12580	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IX88_RS12605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IX88_RS12620	COG0183	Belongs to the thiolase family
IX88_RS12630	COG0583	DNA-binding transcription factor activity
IX88_RS12635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IX88_RS12645	COG1522	sequence-specific DNA binding
IX88_RS12650	COG3135	benzoate transporter
IX88_RS12660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IX88_RS12680	COG0589	response to stress
IX88_RS12685	COG0488	(ABC) transporter
IX88_RS12705	COG4773	Receptor
IX88_RS12735	COG0668	transmembrane transport
IX88_RS12745	COG1309	transcriptional regulator
IX88_RS12755	COG2801	Transposase and inactivated derivatives
IX88_RS12770	COG1605	Chorismate mutase
IX88_RS12810	COG0308	aminopeptidase N
IX88_RS12830	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
IX88_RS12840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IX88_RS12845	COG1454	alcohol dehydrogenase
IX88_RS12865	COG0531	amino acid
IX88_RS12870	COG4303	Ethanolamine ammonia lyase large subunit
IX88_RS12875	COG4302	ethanolamine ammonia-lyase activity
IX88_RS12880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IX88_RS12880	COG0519	Catalyzes the synthesis of GMP from XMP
IX88_RS12885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IX88_RS12910	COG0697	spore germination
IX88_RS12915	COG1923	regulation of RNA biosynthetic process
IX88_RS12925	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IX88_RS12930	COG0802	atpase or kinase
IX88_RS12950	COG1187	pseudouridine synthase activity
IX88_RS12965	COG0583	DNA-binding transcription factor activity
IX88_RS12980	COG2814	Major facilitator Superfamily
IX88_RS12985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX88_RS13010	COG0729	surface antigen
IX88_RS13030	COG0174	glutamine synthetase
IX88_RS13035	COG0745	RESPONSE REGULATOR receiver
IX88_RS13040	COG2205	protein histidine kinase activity
IX88_RS13045	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
IX88_RS13050	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IX88_RS13055	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IX88_RS13080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX88_RS13085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IX88_RS13090	COG1960	acyl-CoA dehydrogenase activity
IX88_RS13105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IX88_RS13110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IX88_RS13130	COG0583	DNA-binding transcription factor activity
IX88_RS13145	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IX88_RS13155	COG3658	cytochrome
IX88_RS13160	COG1215	transferase activity, transferring glycosyl groups
IX88_RS13165	COG1649	PFAM Uncharacterised BCR, COG1649
IX88_RS13165	COG0726	polysaccharide deacetylase
IX88_RS13190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IX88_RS13195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IX88_RS13205	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IX88_RS13230	COG0305	Participates in initiation and elongation during chromosome replication
IX88_RS13235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX88_RS13245	COG1305	Transglutaminase-like
IX88_RS13255	COG2308	Evidence 4 Homologs of previously reported genes of
IX88_RS13285	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IX88_RS13290	COG0138	bifunctional purine biosynthesis protein purh
IX88_RS13295	COG0151	Belongs to the GarS family
IX88_RS13300	COG1464	Belongs to the NlpA lipoprotein family
IX88_RS13305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX88_RS13310	COG2011	ABC-type metal ion transport system permease component
IX88_RS13315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_RS13325	COG1301	dicarboxylic acid transport
IX88_RS13355	COG1794	racemase activity, acting on amino acids and derivatives
IX88_RS13375	COG0745	RESPONSE REGULATOR receiver
IX88_RS13380	COG0642	Histidine kinase
IX88_RS13385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX88_RS13395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IX88_RS13435	COG2351	hydroxyisourate hydrolase activity
IX88_RS13445	COG3008	intermembrane lipid transfer
IX88_RS13445	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IX88_RS13450	COG2995	paraquat-inducible protein a
IX88_RS13480	COG0477	Major facilitator Superfamily
IX88_RS13530	COG2186	Transcriptional regulator
IX88_RS13540	COG0786	glutamate:sodium symporter activity
IX88_RS13545	COG3243	poly(R)-hydroxyalkanoic acid synthase
IX88_RS13570	COG3111	PFAM Bacterial OB fold (BOF) protein
IX88_RS13645	COG3210	domain, Protein
IX88_RS13650	COG2831	hemolysin activation secretion protein
IX88_RS13705	COG1610	YqeY-like protein
IX88_RS13710	COG4783	chaperone-mediated protein folding
IX88_RS13735	COG1286	toxin biosynthetic process
IX88_RS13950	COG0305	Participates in initiation and elongation during chromosome replication
IX88_RS14050	COG0778	Nitroreductase
IX88_RS14060	COG0513	Belongs to the DEAD box helicase family
IX88_RS14080	COG2363	Small membrane protein
IX88_RS14110	COG1234	tRNA 3'-trailer cleavage
IX88_RS14115	COG2195	Cleaves the N-terminal amino acid of tripeptides
IX88_RS14125	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IX88_RS14135	COG2819	hydrolase of the alpha beta superfamily
IX88_RS14140	COG1960	acyl-CoA dehydrogenase activity
IX88_RS14145	COG1301	dicarboxylic acid transport
IX88_RS14150	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IX88_RS14155	COG3139	Protein of unknown function (DUF1315)
IX88_RS14160	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IX88_RS14165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IX88_RS14175	COG0494	nUDIX hydrolase
IX88_RS14185	COG0642	Histidine kinase
IX88_RS14195	COG3111	PFAM Bacterial OB fold (BOF) protein
IX88_RS14200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IX88_RS14210	COG1720	tRNA m6t6A37 methyltransferase activity
IX88_RS14225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX88_RS14230	COG0826	peptidase U32
IX88_RS14235	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IX88_RS14250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS14290	COG1131	(ABC) transporter
IX88_RS14295	COG0842	Transport permease protein
IX88_RS14310	COG0772	Belongs to the SEDS family
IX88_RS14315	COG2951	lytic endotransglycosylase activity
IX88_RS14340	COG2207	Transcriptional regulator
IX88_RS14355	COG0052	Belongs to the universal ribosomal protein uS2 family
IX88_RS14360	COG0024	Methionine aminopeptidase
IX88_RS14370	COG2223	nitrite transmembrane transporter activity
IX88_RS14385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_RS14390	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX88_RS14395	COG1960	acyl-CoA dehydrogenase activity
IX88_RS14410	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IX88_RS14415	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IX88_RS14420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX88_RS14440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX88_RS14445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IX88_RS14450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IX88_RS14485	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IX88_RS14495	COG0174	glutamine synthetase
IX88_RS14510	COG0582	viral genome integration into host DNA
IX88_RS14550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX88_RS14575	COG2314	TM2 domain
IX88_RS14630	COG3566	protein conserved in bacteria
IX88_RS14645	COG3567	Phage-associated protein, HI1409 family
IX88_RS14650	COG5410	chromosome segregation
IX88_RS14825	COG0512	Glutamine amidotransferase of anthranilate synthase
IX88_RS14830	COG0308	aminopeptidase N
IX88_RS14860	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IX88_RS14870	COG0302	gtp cyclohydrolase
IX88_RS14890	COG3739	integral membrane protein
IX88_RS14905	COG1169	isochorismate synthase
IX88_RS14915	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IX88_RS14920	COG1132	(ABC) transporter
IX88_RS14925	COG1132	(ABC) transporter
IX88_RS14940	COG3433	isochorismatase activity
IX88_RS14940	COG1535	isochorismatase
IX88_RS14945	COG1021	2,3-dihydroxybenzoate-AMP ligase
IX88_RS14950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_RS14960	COG4774	siderophore transport
IX88_RS14965	COG4607	ABC-type enterochelin transport system periplasmic component
IX88_RS14970	COG4604	ABC transporter, ATP-binding protein
IX88_RS14975	COG4605	iron ion homeostasis
IX88_RS14980	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX88_RS14985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_RS15000	COG2964	Protein conserved in bacteria
IX88_RS15010	COG1741	Belongs to the pirin family
IX88_RS15035	COG2879	small protein
IX88_RS15040	COG1966	Carbon starvation protein
IX88_RS15060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IX88_RS15085	COG1067	ATP-dependent peptidase activity
IX88_RS15090	COG0583	DNA-binding transcription factor activity
IX88_RS15115	COG1686	Belongs to the peptidase S11 family
IX88_RS15120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IX88_RS15155	COG0616	signal peptide processing
IX88_RS15160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX88_RS15170	COG0573	inorganic phosphate transmembrane transporter activity
IX88_RS15175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IX88_RS15180	COG1113	amino acid transport
IX88_RS15185	COG3961	Belongs to the TPP enzyme family
IX88_RS15190	COG1522	sequence-specific DNA binding
IX88_RS15200	COG0076	glutamate decarboxylase activity
IX88_RS15205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IX88_RS15230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX88_RS15265	COG0352	thiamine-phosphate diphosphorylase activity
IX88_RS15290	COG0612	Peptidase, M16
IX88_RS15300	COG1823	symporter activity
IX88_RS15305	COG0583	DNA-binding transcription factor activity
IX88_RS15310	COG0477	Major facilitator Superfamily
IX88_RS15330	COG1187	pseudouridine synthase activity
IX88_RS15345	COG1686	Belongs to the peptidase S11 family
IX88_RS15350	COG1252	NADH dehydrogenase
IX88_RS15360	COG0415	Belongs to the DNA photolyase family
IX88_RS15375	COG1215	transferase activity, transferring glycosyl groups
IX88_RS15405	COG2070	2-Nitropropane dioxygenase
IX88_RS15460	COG0556	nucleotide-excision repair
IX88_RS15480	COG0436	Aminotransferase
IX88_RS15505	COG4221	oxidoreductase activity
IX88_RS15515	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IX88_RS15520	COG1381	Involved in DNA repair and RecF pathway recombination
IX88_RS15530	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IX88_RS15545	COG0681	Belongs to the peptidase S26 family
IX88_RS15560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX88_RS15580	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IX88_RS15585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IX88_RS15590	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IX88_RS15600	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IX88_RS15605	COG4208	sulfate ABC transporter
IX88_RS15610	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IX88_RS15615	COG0583	DNA-binding transcription factor activity
IX88_RS15620	COG4625	pathogenesis
IX88_RS15635	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IX88_RS15650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IX88_RS15660	COG1051	belongs to the nudix hydrolase family
IX88_RS15660	COG1056	cytidyltransferase-related domain
IX88_RS15665	COG1024	Enoyl-CoA hydratase
IX88_RS15680	COG2814	Major facilitator Superfamily
IX88_RS15685	COG0047	phosphoribosylformylglycinamidine synthase activity
IX88_RS15685	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX88_RS15705	COG1473	amidohydrolase
IX88_RS15710	COG0824	Thioesterase
IX88_RS15730	COG0823	Involved in the tonB-independent uptake of proteins
IX88_RS15750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX88_RS15785	COG0628	permease
IX88_RS15795	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IX88_RS15800	COG0596	Alpha beta hydrolase
IX88_RS15805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IX88_RS15805	COG0616	signal peptide processing
IX88_RS15815	COG2333	competence protein COMEC
IX88_RS15815	COG0658	competence protein
IX88_RS15820	COG1136	(ABC) transporter
IX88_RS15825	COG4591	ABC-type transport system involved in lipoprotein release permease component
IX88_RS15855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS15875	COG0463	Glycosyl transferase, family 2
IX88_RS15905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX88_RS15910	COG1280	lysine exporter protein (LysE YggA)
IX88_RS15920	COG0019	diaminopimelate decarboxylase activity
IX88_RS15930	COG1113	amino acid transport
IX88_RS15945	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IX88_RS15955	COG3339	Conserved Protein
IX88_RS15960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IX88_RS15965	COG0243	molybdopterin cofactor binding
IX88_RS15970	COG1929	Belongs to the glycerate kinase type-1 family
IX88_RS15980	COG0300	oxidoreductase activity
IX88_RS15985	COG0778	Nitroreductase
IX88_RS16010	COG2801	Transposase and inactivated derivatives
IX88_RS16025	COG0789	Transcriptional regulator
IX88_RS16040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_RS16055	COG1309	transcriptional regulator
IX88_RS16135	COG0582	viral genome integration into host DNA
IX88_RS16145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX88_RS16165	COG0741	lytic transglycosylase activity
IX88_RS16185	COG0584	glycerophosphoryl diester phosphodiesterase
IX88_RS16190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IX88_RS16210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IX88_RS16215	COG1597	lipid kinase activity
IX88_RS16230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IX88_RS16235	COG0477	Major facilitator Superfamily
IX88_RS16285	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IX88_RS16290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX88_RS16315	COG0505	Belongs to the CarA family
IX88_RS16335	COG0589	response to stress
IX88_RS16350	COG2843	Capsule synthesis protein
IX88_RS16370	COG2321	neutral zinc metallopeptidase
IX88_RS16375	COG2354	Protein conserved in bacteria
IX88_RS16395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX88_RS16410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX88_RS16415	COG1053	succinate dehydrogenase
IX88_RS16420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IX88_RS16425	COG2009	succinate dehydrogenase
IX88_RS16460	COG2921	Belongs to the UPF0250 family
IX88_RS16465	COG0321	lipoyl(octanoyl) transferase activity
IX88_RS16480	COG0531	amino acid
IX88_RS16490	COG1733	regulation of RNA biosynthetic process
IX88_RS16495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IX88_RS16500	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IX88_RS16500	COG1648	precorrin-2 dehydrogenase activity
IX88_RS16515	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IX88_RS16545	COG0671	phosphoesterase, PA-phosphatase related
IX88_RS16550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX88_RS16560	COG1538	Outer membrane efflux protein
IX88_RS16565	COG0393	Putative heavy-metal-binding
IX88_RS16570	COG0393	Putative heavy-metal-binding
IX88_RS16580	COG1028	Short-chain dehydrogenase reductase Sdr
IX88_RS16590	COG0525	valine-tRNA ligase activity
IX88_RS16610	COG0583	DNA-binding transcription factor activity
IX88_RS16615	COG0004	ammonium transporteR
IX88_RS16625	COG0642	Histidine kinase
IX88_RS16630	COG0745	RESPONSE REGULATOR receiver
IX88_RS16635	COG2194	sulfuric ester hydrolase activity
IX88_RS16655	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX88_RS16670	COG2315	Protein conserved in bacteria
IX88_RS16675	COG0142	geranyltranstransferase activity
IX88_RS16680	COG2828	Protein conserved in bacteria
IX88_RS16685	COG1113	amino acid transport
IX88_RS16705	COG2207	Transcriptional regulator
IX88_RS16730	COG2249	NAD(P)H dehydrogenase (quinone) activity
IX88_RS16740	COG0560	Phosphoserine phosphatase
IX88_RS16750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IX88_RS16760	COG1530	ribonuclease E activity
IX88_RS16765	COG0424	maF-like protein
IX88_RS16770	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IX88_RS16775	COG1792	Involved in formation and maintenance of cell shape
IX88_RS16780	COG1077	Cell shape determining protein MreB Mrl
IX88_RS16785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX88_RS16795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX88_RS16820	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IX88_RS16825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IX88_RS16830	COG1752	Esterase of the alpha-beta hydrolase superfamily
IX88_RS16835	COG1115	amino acid carrier protein
IX88_RS16850	COG2814	Major facilitator Superfamily
IX88_RS16855	COG1289	transmembrane transporter activity
IX88_RS16865	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IX88_RS16905	COG1376	ErfK ybiS ycfS ynhG family protein
IX88_RS16910	COG2832	Protein of unknown function (DUF454)
IX88_RS16920	COG5510	response to toxic substance
IX88_RS16940	COG0840	transmembrane signaling receptor activity
IX88_RS16980	COG3422	double-strand break repair
IX88_RS16985	COG2824	Alkylphosphonate utilization operon protein PhnA
IX88_RS16990	COG3189	MarR family transcriptional regulator
IX88_RS17000	COG0354	folic acid binding
IX88_RS17005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX88_RS17020	COG1902	pentaerythritol trinitrate reductase activity
IX88_RS17025	COG4772	TonB-dependent receptor
IX88_RS17030	COG2094	Belongs to the DNA glycosylase MPG family
IX88_RS17055	COG1217	gtp-binding protein TYPA
IX88_RS17060	COG2233	PERMEase
IX88_RS17070	COG0833	amino acid
IX88_RS17075	COG1690	Belongs to the RtcB family
IX88_RS17085	COG2885	chlorophyll binding
IX88_RS17085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IX88_RS17095	COG0183	Belongs to the thiolase family
IX88_RS17115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IX88_RS17135	COG2207	Transcriptional regulator
IX88_RS17140	COG0183	Belongs to the thiolase family
IX88_RS17170	COG1272	protein, Hemolysin III
IX88_RS17175	COG0477	Major facilitator Superfamily
IX88_RS17190	COG0450	alkyl hydroperoxide reductase
IX88_RS17210	COG0285	dihydrofolate synthase activity
IX88_RS17255	COG4206	TonB-dependent receptor
IX88_RS17260	COG2096	Adenosyltransferase
IX88_RS17265	COG0584	glycerophosphoryl diester phosphodiesterase
IX88_RS17280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IX88_RS17285	COG0745	RESPONSE REGULATOR receiver
IX88_RS17290	COG2205	protein histidine kinase activity
IX88_RS17300	COG1960	acyl-CoA dehydrogenase activity
IX88_RS17305	COG1960	acyl-CoA dehydrogenase activity
IX88_RS17350	COG0438	transferase activity, transferring glycosyl groups
IX88_RS17355	COG1216	Glycosyl transferase, family 2
IX88_RS17360	COG0438	transferase activity, transferring glycosyl groups
IX88_RS17380	COG0438	transferase activity, transferring glycosyl groups
IX88_RS17385	COG0726	polysaccharide deacetylase
IX88_RS17400	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IX88_RS17445	COG1862	Preprotein translocase
IX88_RS17455	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX88_RS17460	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IX88_RS17470	COG3781	membrane
IX88_RS17475	COG0613	PHP domain protein
IX88_RS17485	COG2350	Protein conserved in bacteria
IX88_RS17515	COG1607	acyl-coa hydrolase
IX88_RS17575	COG2199	diguanylate cyclase activity
IX88_RS17585	COG1408	metallophosphoesterase
IX88_RS17590	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IX88_RS17600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IX88_RS17620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX88_RS17625	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IX88_RS17630	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IX88_RS17640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IX88_RS17650	COG2969	positive regulation of protein catabolic process
IX88_RS17665	COG1024	Enoyl-CoA hydratase
IX88_RS17670	COG1960	acyl-CoA dehydrogenase activity
IX88_RS17675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IX88_RS17690	COG1309	transcriptional regulator
IX88_RS17695	COG1960	acyl-CoA dehydrogenase activity
IX88_RS17740	COG1183	phosphatidylcholine synthase activity
IX88_RS17745	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IX88_RS17775	COG1196	nuclear chromosome segregation
IX88_RS17775	COG0741	lytic transglycosylase activity
IX88_RS17775	COG0739	heme binding
IX88_RS17785	COG1702	phosphate starvation-inducible protein PhoH
IX88_RS17820	COG1295	ribonuclease BN
IX88_RS17825	COG0697	spore germination
IX88_RS17830	COG2169	Transcriptional regulator
IX88_RS17835	COG0179	Fumarylacetoacetate (FAA) hydrolase
IX88_RS17880	COG0557	exoribonuclease II activity
IX88_RS17885	COG0339	signal peptide processing
IX88_RS17890	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IX88_RS17920	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IX88_RS17925	COG1960	acyl-CoA dehydrogenase activity