locus-tag	class	description
LGY76_RS00010	COG0592	DNA-directed DNA polymerase activity
LGY76_RS00020	COG0187	DNA topoisomerase II activity
LGY76_RS00030	COG0586	Pfam SNARE associated Golgi protein
LGY76_RS00035	COG0488	(ABC) transporter
LGY76_RS00060	COG0596	Alpha beta hydrolase
LGY76_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGY76_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LGY76_RS00110	COG1047	Peptidyl-prolyl cis-trans
LGY76_RS00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LGY76_RS00125	COG0196	riboflavin kinase activity
LGY76_RS00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGY76_RS00140	COG1309	transcriptional regulator
LGY76_RS00145	COG1116	anion transmembrane transporter activity
LGY76_RS00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGY76_RS00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGY76_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGY76_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGY76_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS00190	COG0546	phosphoglycolate phosphatase activity
LGY76_RS00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGY76_RS00250	COG0728	peptidoglycan biosynthetic process
LGY76_RS00275	COG1596	polysaccharide export
LGY76_RS00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGY76_RS00285	COG1086	Polysaccharide biosynthesis protein
LGY76_RS00290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGY76_RS00295	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGY76_RS00300	COG2089	acid synthase
LGY76_RS00305	COG1045	serine acetyltransferase
LGY76_RS00310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGY76_RS00315	COG0673	inositol 2-dehydrogenase activity
LGY76_RS00320	COG1083	cytidylyl-transferase
LGY76_RS00325	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS00385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LGY76_RS00390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGY76_RS00405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGY76_RS00410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGY76_RS00420	COG2186	Transcriptional regulator
LGY76_RS00430	COG0277	FAD linked oxidase domain protein
LGY76_RS00435	COG1448	Aminotransferase
LGY76_RS00445	COG1802	Transcriptional regulator
LGY76_RS00460	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGY76_RS00520	COG4372	Transposase
LGY76_RS00545	COG0564	pseudouridine synthase activity
LGY76_RS00585	COG0251	oxidation-reduction process
LGY76_RS00590	COG1113	amino acid transport
LGY76_RS00595	COG1113	amino acid transport
LGY76_RS00625	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGY76_RS00630	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS00635	COG1024	Enoyl-CoA hydratase
LGY76_RS00640	COG1024	Enoyl-CoA hydratase
LGY76_RS00660	COG0271	Belongs to the BolA IbaG family
LGY76_RS00670	COG1192	Involved in chromosome partitioning
LGY76_RS00685	COG0586	Pfam SNARE associated Golgi protein
LGY76_RS00690	COG2259	Doxx family
LGY76_RS00695	COG4399	Belongs to the UPF0754 family
LGY76_RS00700	COG0519	Catalyzes the synthesis of GMP from XMP
LGY76_RS00700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGY76_RS00745	COG0281	malic enzyme
LGY76_RS00760	COG2837	iron assimilation
LGY76_RS00765	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS00770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGY76_RS00775	COG1121	(ABC) transporter
LGY76_RS00845	COG0386	Belongs to the glutathione peroxidase family
LGY76_RS00860	COG1309	transcriptional regulator
LGY76_RS00865	COG0697	spore germination
LGY76_RS00875	COG0758	DNA mediated transformation
LGY76_RS00945	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGY76_RS00955	COG0655	NAD(P)H dehydrogenase (quinone) activity
LGY76_RS00995	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGY76_RS01015	COG1253	flavin adenine dinucleotide binding
LGY76_RS01025	COG2860	membrane
LGY76_RS01030	COG0477	Major facilitator Superfamily
LGY76_RS01040	COG0318	PFAM AMP-dependent synthetase and ligase
LGY76_RS01055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGY76_RS01075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGY76_RS01120	COG0589	response to stress
LGY76_RS01125	COG0659	secondary active sulfate transmembrane transporter activity
LGY76_RS01185	COG0347	Belongs to the P(II) protein family
LGY76_RS01190	COG0004	ammonium transporteR
LGY76_RS01200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGY76_RS01200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGY76_RS01240	COG0795	lipopolysaccharide-transporting ATPase activity
LGY76_RS01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGY76_RS01250	COG0793	Belongs to the peptidase S41A family
LGY76_RS01265	COG2197	response regulator
LGY76_RS01275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LGY76_RS01285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGY76_RS01290	COG4974	Belongs to the 'phage' integrase family
LGY76_RS01315	COG0772	Belongs to the SEDS family
LGY76_RS01320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LGY76_RS01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LGY76_RS01330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGY76_RS01355	COG0697	spore germination
LGY76_RS01360	COG1538	Outer membrane efflux protein
LGY76_RS01380	COG3275	phosphorelay sensor kinase activity
LGY76_RS01390	COG0181	hydroxymethylbilane synthase activity
LGY76_RS01435	COG1716	ATPase activity
LGY76_RS01440	COG0546	phosphoglycolate phosphatase activity
LGY76_RS01535	COG0596	Alpha beta hydrolase
LGY76_RS01540	COG2056	Na+-H+ antiporter family
LGY76_RS01555	COG0326	Molecular chaperone. Has ATPase activity
LGY76_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LGY76_RS01635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGY76_RS01640	COG2169	Transcriptional regulator
LGY76_RS01640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGY76_RS01670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGY76_RS01680	COG0497	DNA recombination
LGY76_RS01695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGY76_RS01705	COG0237	dephospho-CoA kinase activity
LGY76_RS01710	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGY76_RS01760	COG0195	Participates in both transcription termination and antitermination
LGY76_RS01775	COG1320	monovalent cation:proton antiporter activity
LGY76_RS01780	COG2212	antiporter activity
LGY76_RS01785	COG1863	multisubunit Na H antiporter MnhE subunit
LGY76_RS01790	COG0651	ATP synthesis coupled electron transport
LGY76_RS01795	COG1006	Multisubunit Na H antiporter MnhC subunit
LGY76_RS01800	COG2111	Na H antiporter
LGY76_RS01800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGY76_RS01815	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGY76_RS01820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGY76_RS01835	COG2226	methyltransferase
LGY76_RS01855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGY76_RS01860	COG1074	ATP-dependent DNA helicase activity
LGY76_RS01865	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGY76_RS01870	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGY76_RS01885	COG0598	Magnesium transport protein CorA
LGY76_RS01890	COG0789	Transcriptional regulator
LGY76_RS01895	COG0484	heat shock protein binding
LGY76_RS01905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LGY76_RS01910	COG0475	glutathione-regulated potassium exporter activity
LGY76_RS01910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGY76_RS01915	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGY76_RS01935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGY76_RS01945	COG4535	Mg2 and Co2 transporter CorC
LGY76_RS01950	COG0425	Belongs to the sulfur carrier protein TusA family
LGY76_RS01955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LGY76_RS01955	COG0644	oxidoreductase
LGY76_RS01965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LGY76_RS01980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGY76_RS01985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LGY76_RS02025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGY76_RS02040	COG0534	Mate efflux family protein
LGY76_RS02050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGY76_RS02055	COG4221	oxidoreductase activity
LGY76_RS02060	COG0583	DNA-binding transcription factor activity
LGY76_RS02075	COG0318	PFAM AMP-dependent synthetase and ligase
LGY76_RS02080	COG1530	ribonuclease E activity
LGY76_RS02090	COG0546	phosphoglycolate phosphatase activity
LGY76_RS02095	COG2378	regulation of single-species biofilm formation
LGY76_RS02100	COG0625	glutathione transferase activity
LGY76_RS02110	COG0583	DNA-binding transcription factor activity
LGY76_RS02175	COG0473	3-isopropylmalate dehydrogenase activity
LGY76_RS02230	COG1301	dicarboxylic acid transport
LGY76_RS02240	COG1560	Kdo2-lipid A biosynthetic process
LGY76_RS02245	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS02250	COG0488	(ABC) transporter
LGY76_RS02255	COG2900	Belongs to the SlyX family
LGY76_RS02265	COG1733	regulation of RNA biosynthetic process
LGY76_RS02290	COG0210	DNA helicase
LGY76_RS02295	COG0724	RNA recognition motif
LGY76_RS02315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGY76_RS02315	COG4651	solute:proton antiporter activity
LGY76_RS02340	COG0788	formyltetrahydrofolate deformylase activity
LGY76_RS02440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGY76_RS02440	COG2813	Specifically methylates the guanine in position
LGY76_RS02450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LGY76_RS02460	COG4774	siderophore transport
LGY76_RS02470	COG0740	serine-type endopeptidase activity
LGY76_RS02490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGY76_RS02490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGY76_RS02495	COG0280	phosphate acetyltransferase
LGY76_RS02495	COG0857	belongs to the CobB CobQ family
LGY76_RS02500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGY76_RS02515	COG0800	Aldolase
LGY76_RS02525	COG3265	gluconokinase activity
LGY76_RS02530	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS02540	COG2267	carboxylic ester hydrolase activity
LGY76_RS02555	COG0793	Belongs to the peptidase S41A family
LGY76_RS02590	COG1426	Protein conserved in bacteria
LGY76_RS02635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGY76_RS02645	COG0318	PFAM AMP-dependent synthetase and ligase
LGY76_RS02660	COG2986	histidine ammonia-lyase
LGY76_RS02700	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS02705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGY76_RS02725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGY76_RS02735	COG1162	GTPase activity
LGY76_RS02740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGY76_RS02755	COG1538	Outer membrane efflux protein
LGY76_RS02760	COG0577	efflux transmembrane transporter activity
LGY76_RS02760	COG1136	(ABC) transporter
LGY76_RS02765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS02790	COG0028	Belongs to the TPP enzyme family
LGY76_RS02795	COG0440	acetolactate synthase activity
LGY76_RS02825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LGY76_RS02840	COG0084	hydrolase, TatD family'
LGY76_RS02855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGY76_RS02865	COG0583	DNA-binding transcription factor activity
LGY76_RS02875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGY76_RS02880	COG2814	Major facilitator Superfamily
LGY76_RS02890	COG0697	spore germination
LGY76_RS02920	COG3622	Belongs to the hyi family
LGY76_RS02925	COG2084	Dehydrogenase
LGY76_RS02930	COG1024	Enoyl-CoA hydratase
LGY76_RS02935	COG0784	Response regulator, receiver
LGY76_RS02935	COG2205	protein histidine kinase activity
LGY76_RS02935	COG5002	protein histidine kinase activity
LGY76_RS02955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGY76_RS02965	COG3956	TIGRFAM MazG family protein
LGY76_RS02970	COG1555	photosystem II stabilization
LGY76_RS02975	COG0617	tRNA 3'-terminal CCA addition
LGY76_RS02980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGY76_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGY76_RS03005	COG3028	Belongs to the UPF0307 family
LGY76_RS03010	COG0318	PFAM AMP-dependent synthetase and ligase
LGY76_RS03025	COG0625	glutathione transferase activity
LGY76_RS03030	COG1238	metal cluster binding
LGY76_RS03075	COG0072	phenylalanine-tRNA ligase activity
LGY76_RS03105	COG0248	Ppx GppA phosphatase
LGY76_RS03115	COG0037	tRNA processing
LGY76_RS03165	COG1764	response to oxidative stress
LGY76_RS03170	COG1846	Transcriptional regulator
LGY76_RS03180	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGY76_RS03240	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGY76_RS03245	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LGY76_RS03250	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGY76_RS03260	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LGY76_RS03310	COG1214	PFAM Peptidase M22, glycoprotease
LGY76_RS03335	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGY76_RS03340	COG0561	phosphatase activity
LGY76_RS03350	COG2132	Multicopper oxidase
LGY76_RS03355	COG3667	copper resistance
LGY76_RS03370	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGY76_RS03375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LGY76_RS03380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGY76_RS03410	COG1063	alcohol dehydrogenase
LGY76_RS03415	COG0583	DNA-binding transcription factor activity
LGY76_RS03420	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS03425	COG2814	Major facilitator Superfamily
LGY76_RS03430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LGY76_RS03440	COG1053	succinate dehydrogenase
LGY76_RS03445	COG0583	DNA-binding transcription factor activity
LGY76_RS03460	COG0583	DNA-binding transcription factor activity
LGY76_RS03490	COG0583	DNA-binding transcription factor activity
LGY76_RS03505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGY76_RS03530	COG0384	phenazine biosynthesis protein PhzF
LGY76_RS03555	COG4993	Dehydrogenase
LGY76_RS03635	COG4372	Transposase
LGY76_RS03645	COG2205	protein histidine kinase activity
LGY76_RS03655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGY76_RS03675	COG0745	RESPONSE REGULATOR receiver
LGY76_RS03715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LGY76_RS03745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGY76_RS03750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGY76_RS03770	COG0583	DNA-binding transcription factor activity
LGY76_RS03790	COG0668	transmembrane transport
LGY76_RS03800	COG2081	HI0933 family
LGY76_RS03805	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGY76_RS03835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGY76_RS03835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGY76_RS03845	COG0489	protein tyrosine kinase activity
LGY76_RS03895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGY76_RS03905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGY76_RS03920	COG0730	response to heat
LGY76_RS03930	COG1196	nuclear chromosome segregation
LGY76_RS03950	COG2223	nitrite transmembrane transporter activity
LGY76_RS03955	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LGY76_RS03960	COG1877	trehalose-phosphatase activity
LGY76_RS03965	COG0596	Alpha beta hydrolase
LGY76_RS03965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGY76_RS03965	COG2226	methyltransferase
LGY76_RS03980	COG4106	trans-aconitate 2-methyltransferase activity
LGY76_RS03995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LGY76_RS04000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LGY76_RS04005	COG0009	L-threonylcarbamoyladenylate synthase
LGY76_RS04010	COG3101	peptidyl-lysine hydroxylation
LGY76_RS04015	COG1399	metal-binding, possibly nucleic acid-binding protein
LGY76_RS04040	COG1652	LysM domain
LGY76_RS04045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LGY76_RS04045	COG0352	thiamine-phosphate diphosphorylase activity
LGY76_RS04045	COG0351	phosphomethylpyrimidine kinase
LGY76_RS04055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGY76_RS04085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGY76_RS04115	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGY76_RS04130	COG0358	DNA primase activity
LGY76_RS04140	COG0564	pseudouridine synthase activity
LGY76_RS04165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGY76_RS04185	COG0583	DNA-binding transcription factor activity
LGY76_RS04190	COG0473	3-isopropylmalate dehydrogenase activity
LGY76_RS04200	COG0657	acetylesterase activity
LGY76_RS04210	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS04230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGY76_RS04230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGY76_RS04245	COG1981	membrane
LGY76_RS04290	COG0456	acetyltransferase
LGY76_RS04300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LGY76_RS04305	COG0492	ferredoxin-NADP+ reductase activity
LGY76_RS04310	COG1674	ftsk spoiiie
LGY76_RS04310	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGY76_RS04315	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS04340	COG2894	cell division
LGY76_RS04355	COG0204	Acyl-transferase
LGY76_RS04360	COG2885	chlorophyll binding
LGY76_RS04365	COG0210	DNA helicase
LGY76_RS04375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGY76_RS04390	COG0121	glutamine amidotransferase
LGY76_RS04410	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGY76_RS04415	COG0735	belongs to the Fur family
LGY76_RS04440	COG0420	3'-5' exonuclease activity
LGY76_RS04460	COG1090	epimerase
LGY76_RS04475	COG2050	protein possibly involved in aromatic compounds catabolism
LGY76_RS04485	COG2814	Major facilitator Superfamily
LGY76_RS04490	COG0405	Gamma-glutamyltransferase
LGY76_RS04560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGY76_RS04655	COG1484	DNA-dependent DNA replication
LGY76_RS04850	COG2026	Addiction module toxin, RelE StbE family
LGY76_RS04895	COG4372	Transposase
LGY76_RS04920	COG0592	DNA-directed DNA polymerase activity
LGY76_RS05030	COG0582	viral genome integration into host DNA
LGY76_RS05085	COG0629	single-stranded DNA binding
LGY76_RS05120	COG0084	hydrolase, TatD family'
LGY76_RS05140	COG0477	Major facilitator Superfamily
LGY76_RS05145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGY76_RS05155	COG1595	DNA-templated transcription, initiation
LGY76_RS05210	COG0531	amino acid
LGY76_RS05215	COG2040	homocysteine
LGY76_RS05240	COG1309	transcriptional regulator
LGY76_RS05245	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGY76_RS05250	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGY76_RS05260	COG1607	acyl-coa hydrolase
LGY76_RS05270	COG0523	cobalamin synthesis protein
LGY76_RS05280	COG4681	YaeQ
LGY76_RS05290	COG1649	PFAM Uncharacterised BCR, COG1649
LGY76_RS05290	COG0726	polysaccharide deacetylase
LGY76_RS05295	COG1215	transferase activity, transferring glycosyl groups
LGY76_RS05305	COG1024	Enoyl-CoA hydratase
LGY76_RS05320	COG1414	Transcriptional regulator
LGY76_RS05340	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS05350	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGY76_RS05355	COG2271	Major facilitator Superfamily
LGY76_RS05365	COG2267	carboxylic ester hydrolase activity
LGY76_RS05370	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS05385	COG0028	Belongs to the TPP enzyme family
LGY76_RS05395	COG0477	Major facilitator Superfamily
LGY76_RS05400	COG0242	peptide deformylase activity
LGY76_RS05405	COG2066	Belongs to the glutaminase family
LGY76_RS05410	COG2207	Transcriptional regulator
LGY76_RS05415	COG2223	nitrite transmembrane transporter activity
LGY76_RS05430	COG0583	DNA-binding transcription factor activity
LGY76_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS05440	COG2271	Major facilitator Superfamily
LGY76_RS05445	COG3959	Transketolase, thiamine diphosphate binding domain
LGY76_RS05450	COG3958	Transketolase
LGY76_RS05460	COG0306	phosphate transporter
LGY76_RS05480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LGY76_RS05525	COG4181	ATPase activity
LGY76_RS05530	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGY76_RS05555	COG0583	DNA-binding transcription factor activity
LGY76_RS05565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGY76_RS05570	COG1773	rubredoxin
LGY76_RS05625	COG2851	Citrate transporter
LGY76_RS05630	COG1253	flavin adenine dinucleotide binding
LGY76_RS05670	COG0804	urea catabolic process
LGY76_RS05680	COG0830	nickel cation binding
LGY76_RS05695	COG0742	ribosomal rna small subunit methyltransferase
LGY76_RS05700	COG0768	penicillin binding
LGY76_RS05725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGY76_RS05730	COG2878	Part of a membrane complex involved in electron transport
LGY76_RS05735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LGY76_RS05745	COG3384	dioxygenase
LGY76_RS05770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGY76_RS06095	COG0739	heme binding
LGY76_RS06140	COG2194	sulfuric ester hydrolase activity
LGY76_RS06200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGY76_RS06215	COG0305	Participates in initiation and elongation during chromosome replication
LGY76_RS06315	COG4695	Portal protein
LGY76_RS06415	COG0006	proline dipeptidase activity
LGY76_RS06420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGY76_RS06425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGY76_RS06445	COG1279	arginine transmembrane transporter activity
LGY76_RS06450	COG0583	DNA-binding transcription factor activity
LGY76_RS06490	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGY76_RS06495	COG0741	lytic transglycosylase activity
LGY76_RS06495	COG1388	LysM domain
LGY76_RS06495	COG0741	lytic transglycosylase activity
LGY76_RS06495	COG1388	LysM domain
LGY76_RS06505	COG4174	ABC transporter (Permease)
LGY76_RS06510	COG4239	(ABC) transporter, permease
LGY76_RS06515	COG4172	Belongs to the ABC transporter superfamily
LGY76_RS06535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGY76_RS06545	COG4251	negative regulation of phosphorylation
LGY76_RS06545	COG3706	GGDEF domain
LGY76_RS06545	COG5001	Diguanylate cyclase
LGY76_RS06545	COG2203	Gaf domain
LGY76_RS06555	COG1902	pentaerythritol trinitrate reductase activity
LGY76_RS06555	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGY76_RS06625	COG1309	transcriptional regulator
LGY76_RS06630	COG1741	Belongs to the pirin family
LGY76_RS06645	COG2072	flavoprotein involved in K transport
LGY76_RS06655	COG2252	PERMEase
LGY76_RS06660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGY76_RS06665	COG3038	cytochrome b561
LGY76_RS06675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGY76_RS06685	COG0527	aspartate kinase activity
LGY76_RS06695	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGY76_RS06705	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGY76_RS06720	COG0667	Aldo Keto reductase
LGY76_RS06740	COG1765	OsmC-like protein
LGY76_RS06755	COG0542	response to heat
LGY76_RS06790	COG2885	chlorophyll binding
LGY76_RS06800	COG0625	glutathione transferase activity
LGY76_RS06805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LGY76_RS06825	COG3634	alkyl hydroperoxide reductase activity
LGY76_RS06835	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LGY76_RS06845	COG0450	alkyl hydroperoxide reductase
LGY76_RS06850	COG1643	Atp-dependent helicase
LGY76_RS06865	COG2814	Major facilitator Superfamily
LGY76_RS06870	COG3135	benzoate transporter
LGY76_RS06875	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS06880	COG0543	2 iron, 2 sulfur cluster binding
LGY76_RS06880	COG0633	Ferredoxin
LGY76_RS06885	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LGY76_RS06890	COG4638	Rieske (2fe-2S)
LGY76_RS06900	COG0583	DNA-binding transcription factor activity
LGY76_RS06950	COG1570	exodeoxyribonuclease VII activity
LGY76_RS06980	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS06985	COG1278	Cold shock
LGY76_RS07020	COG2814	Major facilitator Superfamily
LGY76_RS07055	COG0517	IMP dehydrogenase activity
LGY76_RS07055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGY76_RS07060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGY76_RS07070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGY76_RS07075	COG1137	ATPase activity
LGY76_RS07080	COG1538	Outer membrane efflux protein
LGY76_RS07110	COG4122	O-methyltransferase activity
LGY76_RS07120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LGY76_RS07135	COG1522	sequence-specific DNA binding
LGY76_RS07140	COG5006	permease, DMT superfamily
LGY76_RS07150	COG1560	Kdo2-lipid A biosynthetic process
LGY76_RS07165	COG2814	Major facilitator Superfamily
LGY76_RS07185	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGY76_RS07235	COG0583	DNA-binding transcription factor activity
LGY76_RS07240	COG1914	H( )-stimulated, divalent metal cation uptake system
LGY76_RS07260	COG4770	biotin carboxylase activity
LGY76_RS07265	COG0038	chloride channel
LGY76_RS07285	COG1309	transcriptional regulator
LGY76_RS07295	COG1063	alcohol dehydrogenase
LGY76_RS07310	COG0439	Biotin carboxylase
LGY76_RS07315	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGY76_RS07335	COG0864	Transcriptional regulator
LGY76_RS07345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGY76_RS07350	COG1116	anion transmembrane transporter activity
LGY76_RS07470	COG0590	tRNA wobble adenosine to inosine editing
LGY76_RS07475	COG2807	transmembrane transport
LGY76_RS07490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGY76_RS07505	COG0789	Transcriptional regulator
LGY76_RS07515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGY76_RS07535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGY76_RS07545	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGY76_RS07560	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS07565	COG0531	amino acid
LGY76_RS07570	COG1760	l-serine dehydratase
LGY76_RS07575	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS07575	COG2030	dehydratase
LGY76_RS07580	COG3396	Phenylacetate-CoA oxygenase
LGY76_RS07585	COG3460	Phenylacetate-CoA oxygenase
LGY76_RS07590	COG3396	Phenylacetate-CoA oxygenase
LGY76_RS07595	COG2151	metal-sulfur cluster biosynthetic enzyme
LGY76_RS07600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGY76_RS07605	COG1024	Enoyl-CoA hydratase
LGY76_RS07610	COG1024	Enoyl-CoA hydratase
LGY76_RS07615	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGY76_RS07620	COG0183	Belongs to the thiolase family
LGY76_RS07625	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LGY76_RS07630	COG3327	negative regulation of DNA-templated transcription, initiation
LGY76_RS07640	COG2050	protein possibly involved in aromatic compounds catabolism
LGY76_RS07670	COG0753	catalase activity
LGY76_RS07675	COG3038	cytochrome b561
LGY76_RS07695	COG2267	carboxylic ester hydrolase activity
LGY76_RS07700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGY76_RS07705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGY76_RS07710	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS07720	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LGY76_RS07730	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS07735	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LGY76_RS07740	COG0583	DNA-binding transcription factor activity
LGY76_RS07750	COG1414	Transcriptional regulator
LGY76_RS07755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGY76_RS07765	COG1840	ABC-type Fe3 transport system, periplasmic component
LGY76_RS07770	COG3842	ATPase activity
LGY76_RS07785	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LGY76_RS07790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGY76_RS07795	COG2814	Major facilitator Superfamily
LGY76_RS07800	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS07815	COG1024	Enoyl-CoA hydratase
LGY76_RS07825	COG2814	Major facilitator Superfamily
LGY76_RS07835	COG0183	Belongs to the thiolase family
LGY76_RS07840	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGY76_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS07850	COG1024	Enoyl-CoA hydratase
LGY76_RS07855	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS07860	COG2814	Major facilitator Superfamily
LGY76_RS07865	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGY76_RS07870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGY76_RS07880	COG2814	Major facilitator Superfamily
LGY76_RS07890	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS07905	COG0583	DNA-binding transcription factor activity
LGY76_RS07915	COG4770	biotin carboxylase activity
LGY76_RS07920	COG1024	Enoyl-CoA hydratase
LGY76_RS07925	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LGY76_RS07930	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS07935	COG1309	transcriptional regulator
LGY76_RS07940	COG0318	PFAM AMP-dependent synthetase and ligase
LGY76_RS07960	COG0583	DNA-binding transcription factor activity
LGY76_RS08010	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS08030	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGY76_RS08050	COG2205	protein histidine kinase activity
LGY76_RS08050	COG0784	Response regulator, receiver
LGY76_RS08070	COG0765	amino acid transport
LGY76_RS08075	COG0765	amino acid transport
LGY76_RS08080	COG1126	abc transporter atp-binding protein
LGY76_RS08085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGY76_RS08090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGY76_RS08105	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS08115	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGY76_RS08120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGY76_RS08125	COG1045	serine acetyltransferase
LGY76_RS08140	COG0583	DNA-binding transcription factor activity
LGY76_RS08145	COG0625	glutathione transferase activity
LGY76_RS08150	COG0625	glutathione transferase activity
LGY76_RS08155	COG0583	DNA-binding transcription factor activity
LGY76_RS08165	COG1346	cytolysis
LGY76_RS08185	COG2814	Major facilitator Superfamily
LGY76_RS08195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LGY76_RS08200	COG3052	prosthetic group binding
LGY76_RS08220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGY76_RS08240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGY76_RS08250	COG1294	oxidase, subunit
LGY76_RS08255	COG1271	oxidase subunit
LGY76_RS08275	COG0477	Major facilitator Superfamily
LGY76_RS08285	COG4521	taurine ABC transporter
LGY76_RS08290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LGY76_RS08295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGY76_RS08300	COG2175	clavaminate synthase activity
LGY76_RS08310	COG1953	Uracil, thiamine, allantoin
LGY76_RS08320	COG0583	DNA-binding transcription factor activity
LGY76_RS08330	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LGY76_RS08345	COG0640	Transcriptional regulator
LGY76_RS08350	COG0798	PFAM Bile acid sodium symporter
LGY76_RS08355	COG0583	DNA-binding transcription factor activity
LGY76_RS08370	COG3634	alkyl hydroperoxide reductase activity
LGY76_RS08405	COG1301	dicarboxylic acid transport
LGY76_RS08410	COG0436	Aminotransferase
LGY76_RS08420	COG0386	Belongs to the glutathione peroxidase family
LGY76_RS08460	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LGY76_RS08485	COG0012	GTP binding
LGY76_RS08490	COG2011	ABC-type metal ion transport system permease component
LGY76_RS08495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGY76_RS08505	COG1464	Belongs to the NlpA lipoprotein family
LGY76_RS08535	COG0765	amino acid transport
LGY76_RS08540	COG0765	amino acid transport
LGY76_RS08545	COG1126	abc transporter atp-binding protein
LGY76_RS08555	COG1522	sequence-specific DNA binding
LGY76_RS08570	COG1309	transcriptional regulator
LGY76_RS08590	COG0583	DNA-binding transcription factor activity
LGY76_RS08600	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LGY76_RS08615	COG0697	spore germination
LGY76_RS08640	COG3121	Chaperone
LGY76_RS08645	COG3539	Fimbrial protein
LGY76_RS08670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGY76_RS08670	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGY76_RS08715	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGY76_RS08725	COG2353	YceI-like domain
LGY76_RS08735	COG3698	Phosphodiester glycosidase
LGY76_RS08750	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LGY76_RS08755	COG0506	proline dehydrogenase activity
LGY76_RS08755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGY76_RS08755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGY76_RS08765	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGY76_RS08770	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LGY76_RS08790	COG1132	(ABC) transporter
LGY76_RS08795	COG3122	Protein conserved in bacteria
LGY76_RS08800	COG3619	membrane
LGY76_RS08815	COG0640	Transcriptional regulator
LGY76_RS08825	COG2850	peptidyl-arginine hydroxylation
LGY76_RS08830	COG0424	maF-like protein
LGY76_RS08850	COG0191	fructose-bisphosphate aldolase activity
LGY76_RS08855	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGY76_RS08870	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGY76_RS08880	COG1192	Involved in chromosome partitioning
LGY76_RS08885	COG1475	DNA binding
LGY76_RS08890	COG0811	peptide transport
LGY76_RS08900	COG1132	(ABC) transporter
LGY76_RS08905	COG1663	tetraacyldisaccharide 4'-kinase activity
LGY76_RS08925	COG0084	hydrolase, TatD family'
LGY76_RS08990	COG0776	regulation of translation
LGY76_RS09020	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGY76_RS09025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGY76_RS09075	COG0339	signal peptide processing
LGY76_RS09085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGY76_RS09120	COG0702	epimerase
LGY76_RS09125	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGY76_RS09145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGY76_RS09175	COG0316	Belongs to the HesB IscA family
LGY76_RS09180	COG0822	iron-sulfur transferase activity
LGY76_RS09205	COG0776	regulation of translation
LGY76_RS09210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGY76_RS09215	COG2207	Transcriptional regulator
LGY76_RS09220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGY76_RS09225	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS09230	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS09245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGY76_RS09265	COG4264	IucA IucC family
LGY76_RS09270	COG4264	IucA IucC family
LGY76_RS09310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGY76_RS09325	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LGY76_RS09345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGY76_RS09350	COG0730	response to heat
LGY76_RS09370	COG4773	Receptor
LGY76_RS09375	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGY76_RS09390	COG1131	(ABC) transporter
LGY76_RS09395	COG0842	Transport permease protein
LGY76_RS09400	COG0842	Transport permease protein
LGY76_RS09455	COG2226	methyltransferase
LGY76_RS09485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGY76_RS09520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGY76_RS09530	COG0133	tryptophan synthase activity
LGY76_RS09545	COG3706	GGDEF domain
LGY76_RS09560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGY76_RS09565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LGY76_RS09570	COG0022	dehydrogenase e1 component
LGY76_RS09575	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGY76_RS09580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGY76_RS09590	COG1063	alcohol dehydrogenase
LGY76_RS09595	COG3781	membrane
LGY76_RS09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGY76_RS09605	COG3453	Protein conserved in bacteria
LGY76_RS09620	COG0730	response to heat
LGY76_RS09635	COG2207	Transcriptional regulator
LGY76_RS09635	COG3708	Transcriptional regulator
LGY76_RS09640	COG1733	regulation of RNA biosynthetic process
LGY76_RS09645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGY76_RS09655	COG2188	Transcriptional regulator
LGY76_RS09670	COG4521	taurine ABC transporter
LGY76_RS09675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGY76_RS09690	COG3328	transposase activity
LGY76_RS09705	COG0477	Major facilitator Superfamily
LGY76_RS09715	COG1027	Aspartate ammonia-lyase
LGY76_RS09730	COG0583	DNA-binding transcription factor activity
LGY76_RS09735	COG0583	DNA-binding transcription factor activity
LGY76_RS09740	COG0183	Belongs to the thiolase family
LGY76_RS09745	COG2031	fatty acid transporter
LGY76_RS09750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGY76_RS09760	COG0583	DNA-binding transcription factor activity
LGY76_RS09770	COG2610	gluconate transmembrane transporter activity
LGY76_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS09785	COG2207	Transcriptional regulator
LGY76_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS09825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGY76_RS09825	COG0543	2 iron, 2 sulfur cluster binding
LGY76_RS09830	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LGY76_RS09835	COG4638	Rieske (2fe-2S)
LGY76_RS09845	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGY76_RS09850	COG4149	molybdate abc transporter
LGY76_RS09855	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LGY76_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS09865	COG1535	isochorismatase
LGY76_RS09865	COG3433	isochorismatase activity
LGY76_RS09925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGY76_RS09940	COG0753	catalase activity
LGY76_RS09950	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LGY76_RS09980	COG3539	Fimbrial protein
LGY76_RS10000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGY76_RS10020	COG2072	flavoprotein involved in K transport
LGY76_RS10030	COG1538	Outer membrane efflux protein
LGY76_RS10035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGY76_RS10040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS10045	COG0745	RESPONSE REGULATOR receiver
LGY76_RS10050	COG2205	protein histidine kinase activity
LGY76_RS10060	COG2207	Transcriptional regulator
LGY76_RS10075	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS10125	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGY76_RS10245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGY76_RS10265	COG1120	ATPase activity
LGY76_RS10270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGY76_RS10280	COG1064	alcohol dehydrogenase
LGY76_RS10295	COG2207	Transcriptional regulator
LGY76_RS10300	COG2084	Dehydrogenase
LGY76_RS10310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGY76_RS10315	COG0583	DNA-binding transcription factor activity
LGY76_RS10325	COG0129	dihydroxy-acid dehydratase activity
LGY76_RS10330	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS10345	COG1566	PFAM secretion protein HlyD family protein
LGY76_RS10360	COG4372	Transposase
LGY76_RS10390	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGY76_RS10420	COG0583	DNA-binding transcription factor activity
LGY76_RS10435	COG2188	Transcriptional regulator
LGY76_RS10465	COG3210	domain, Protein
LGY76_RS10470	COG2831	hemolysin activation secretion protein
LGY76_RS10480	COG1473	amidohydrolase
LGY76_RS10510	COG0583	DNA-binding transcription factor activity
LGY76_RS10515	COG1335	isochorismatase
LGY76_RS10525	COG1309	transcriptional regulator
LGY76_RS10555	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LGY76_RS10565	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGY76_RS10565	COG1902	pentaerythritol trinitrate reductase activity
LGY76_RS10570	COG1846	Transcriptional regulator
LGY76_RS10590	COG0753	catalase activity
LGY76_RS10605	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS10620	COG3162	membrane
LGY76_RS10630	COG3829	transcription factor binding
LGY76_RS10635	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS10640	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS10660	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS10680	COG2186	Transcriptional regulator
LGY76_RS10690	COG0583	DNA-binding transcription factor activity
LGY76_RS10695	COG4948	Mandelate Racemase Muconate Lactonizing
LGY76_RS10700	COG4829	muconolactone delta-isomerase
LGY76_RS10710	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGY76_RS10715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGY76_RS10720	COG0183	Belongs to the thiolase family
LGY76_RS10725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LGY76_RS10735	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS10745	COG3733	amine oxidase
LGY76_RS10755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGY76_RS10765	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS10775	COG4638	Rieske (2fe-2S)
LGY76_RS10795	COG0154	amidase activity
LGY76_RS10805	COG2814	Major facilitator Superfamily
LGY76_RS10830	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS10835	COG0583	DNA-binding transcription factor activity
LGY76_RS10840	COG1414	Transcriptional regulator
LGY76_RS10855	COG2391	methyltransferase activity
LGY76_RS10865	COG4993	Dehydrogenase
LGY76_RS10870	COG3659	wide pore channel activity
LGY76_RS10875	COG3420	alginic acid biosynthetic process
LGY76_RS10880	COG0710	3-dehydroquinate dehydratase activity
LGY76_RS10885	COG3485	protocatechuate 3,4-dioxygenase
LGY76_RS10890	COG3485	protocatechuate 3,4-dioxygenase
LGY76_RS10895	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LGY76_RS10900	COG2271	Major facilitator Superfamily
LGY76_RS10905	COG0596	Alpha beta hydrolase
LGY76_RS10910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGY76_RS10915	COG0183	Belongs to the thiolase family
LGY76_RS10920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LGY76_RS10925	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LGY76_RS10935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGY76_RS10940	COG2323	membrane
LGY76_RS10985	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGY76_RS10985	COG1902	pentaerythritol trinitrate reductase activity
LGY76_RS11010	COG0542	response to heat
LGY76_RS11015	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGY76_RS11045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LGY76_RS11050	COG0569	domain protein
LGY76_RS11055	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGY76_RS11070	COG4774	siderophore transport
LGY76_RS11075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGY76_RS11085	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGY76_RS11105	COG1294	oxidase, subunit
LGY76_RS11110	COG4890	Cyd operon protein YbgT
LGY76_RS11125	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LGY76_RS11135	COG0552	protein localization to endoplasmic reticulum
LGY76_RS11160	COG0516	GMP reductase activity
LGY76_RS11160	COG0517	IMP dehydrogenase activity
LGY76_RS11165	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGY76_RS11170	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGY76_RS11180	COG0583	DNA-binding transcription factor activity
LGY76_RS11185	COG0024	Methionine aminopeptidase
LGY76_RS11215	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGY76_RS11215	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGY76_RS11220	COG1105	Belongs to the carbohydrate kinase PfkB family
LGY76_RS11225	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGY76_RS11225	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGY76_RS11225	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGY76_RS11245	COG3300	MHYT domain
LGY76_RS11245	COG5001	Diguanylate cyclase
LGY76_RS11260	COG2135	peptidase activity
LGY76_RS11265	COG0659	secondary active sulfate transmembrane transporter activity
LGY76_RS11285	COG1113	amino acid transport
LGY76_RS11295	COG1522	sequence-specific DNA binding
LGY76_RS11320	COG1011	Hydrolase
LGY76_RS11325	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGY76_RS11335	COG2137	regulation of response to DNA damage stimulus
LGY76_RS11350	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGY76_RS11385	COG0575	Belongs to the CDS family
LGY76_RS11390	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LGY76_RS11410	COG3852	Histidine kinase
LGY76_RS11415	COG2204	response regulator
LGY76_RS11470	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGY76_RS11475	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGY76_RS11495	COG0697	spore germination
LGY76_RS11500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGY76_RS11510	COG0303	'Molybdopterin
LGY76_RS11515	COG0315	cyclic pyranopterin monophosphate synthase activity
LGY76_RS11515	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGY76_RS11530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGY76_RS11535	COG0243	molybdopterin cofactor binding
LGY76_RS11545	COG0243	molybdopterin cofactor binding
LGY76_RS11550	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGY76_RS11555	COG2146	nitrite reductase [NAD(P)H] activity
LGY76_RS11555	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGY76_RS11565	COG0745	RESPONSE REGULATOR receiver
LGY76_RS11570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGY76_RS11570	COG1116	anion transmembrane transporter activity
LGY76_RS11590	COG0511	ligase activity, forming carbon-carbon bonds
LGY76_RS11605	COG2814	Major facilitator Superfamily
LGY76_RS11670	COG0739	heme binding
LGY76_RS11790	COG5410	chromosome segregation
LGY76_RS11955	COG0069	glutamate synthase activity
LGY76_RS11975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LGY76_RS11985	COG1454	alcohol dehydrogenase
LGY76_RS11990	COG0824	Thioesterase
LGY76_RS12000	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LGY76_RS12015	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGY76_RS12020	COG2030	dehydratase
LGY76_RS12030	COG0183	Belongs to the thiolase family
LGY76_RS12040	COG0583	DNA-binding transcription factor activity
LGY76_RS12045	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGY76_RS12055	COG1522	sequence-specific DNA binding
LGY76_RS12060	COG3135	benzoate transporter
LGY76_RS12070	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGY76_RS12095	COG0589	response to stress
LGY76_RS12100	COG0488	(ABC) transporter
LGY76_RS12120	COG4773	Receptor
LGY76_RS12155	COG0668	transmembrane transport
LGY76_RS12165	COG1309	transcriptional regulator
LGY76_RS12170	COG4372	Transposase
LGY76_RS12200	COG1605	Chorismate mutase
LGY76_RS12230	COG0308	aminopeptidase N
LGY76_RS12250	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGY76_RS12260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGY76_RS12265	COG1454	alcohol dehydrogenase
LGY76_RS12285	COG0531	amino acid
LGY76_RS12290	COG4303	Ethanolamine ammonia lyase large subunit
LGY76_RS12295	COG4302	ethanolamine ammonia-lyase activity
LGY76_RS12300	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGY76_RS12300	COG0519	Catalyzes the synthesis of GMP from XMP
LGY76_RS12305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LGY76_RS12315	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGY76_RS12330	COG0697	spore germination
LGY76_RS12335	COG1923	regulation of RNA biosynthetic process
LGY76_RS12345	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGY76_RS12350	COG0802	atpase or kinase
LGY76_RS12370	COG1187	pseudouridine synthase activity
LGY76_RS12385	COG0583	DNA-binding transcription factor activity
LGY76_RS12400	COG2814	Major facilitator Superfamily
LGY76_RS12405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGY76_RS12430	COG0729	surface antigen
LGY76_RS12450	COG0174	glutamine synthetase
LGY76_RS12455	COG0745	RESPONSE REGULATOR receiver
LGY76_RS12460	COG2205	protein histidine kinase activity
LGY76_RS12470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGY76_RS12475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LGY76_RS12500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGY76_RS12505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGY76_RS12510	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS12525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LGY76_RS12530	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LGY76_RS12550	COG0583	DNA-binding transcription factor activity
LGY76_RS12565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGY76_RS12575	COG3658	cytochrome
LGY76_RS12580	COG1215	transferase activity, transferring glycosyl groups
LGY76_RS12585	COG0726	polysaccharide deacetylase
LGY76_RS12585	COG1649	PFAM Uncharacterised BCR, COG1649
LGY76_RS12610	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGY76_RS12615	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGY76_RS12625	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGY76_RS12650	COG0305	Participates in initiation and elongation during chromosome replication
LGY76_RS12655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGY76_RS12665	COG1305	Transglutaminase-like
LGY76_RS12675	COG2308	Evidence 4 Homologs of previously reported genes of
LGY76_RS12705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGY76_RS12710	COG0138	bifunctional purine biosynthesis protein purh
LGY76_RS12715	COG0151	Belongs to the GarS family
LGY76_RS12720	COG1464	Belongs to the NlpA lipoprotein family
LGY76_RS12725	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LGY76_RS12730	COG2011	ABC-type metal ion transport system permease component
LGY76_RS12735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGY76_RS12745	COG1301	dicarboxylic acid transport
LGY76_RS12785	COG2433	Pfam Transposase IS66
LGY76_RS12795	COG3173	Aminoglycoside phosphotransferase
LGY76_RS12800	COG0488	(ABC) transporter
LGY76_RS12830	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGY76_RS12830	COG3008	intermembrane lipid transfer
LGY76_RS12835	COG2995	paraquat-inducible protein a
LGY76_RS12845	COG2985	domain, Protein
LGY76_RS12875	COG0477	Major facilitator Superfamily
LGY76_RS12925	COG2186	Transcriptional regulator
LGY76_RS12935	COG0786	glutamate:sodium symporter activity
LGY76_RS12940	COG3243	poly(R)-hydroxyalkanoic acid synthase
LGY76_RS12975	COG3111	PFAM Bacterial OB fold (BOF) protein
LGY76_RS13065	COG1610	YqeY-like protein
LGY76_RS13070	COG4783	chaperone-mediated protein folding
LGY76_RS13095	COG1286	toxin biosynthetic process
LGY76_RS13125	COG0778	Nitroreductase
LGY76_RS13135	COG0513	Belongs to the DEAD box helicase family
LGY76_RS13160	COG2363	Small membrane protein
LGY76_RS13190	COG1234	tRNA 3'-trailer cleavage
LGY76_RS13195	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGY76_RS13205	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGY76_RS13215	COG2819	hydrolase of the alpha beta superfamily
LGY76_RS13220	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS13225	COG1301	dicarboxylic acid transport
LGY76_RS13230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGY76_RS13235	COG3139	Protein of unknown function (DUF1315)
LGY76_RS13240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGY76_RS13245	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGY76_RS13255	COG0494	nUDIX hydrolase
LGY76_RS13265	COG0642	Histidine kinase
LGY76_RS13280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGY76_RS13290	COG1720	tRNA m6t6A37 methyltransferase activity
LGY76_RS13305	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGY76_RS13310	COG0826	peptidase U32
LGY76_RS13315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGY76_RS13325	COG4598	ABC transporter
LGY76_RS13330	COG4160	amino acid transport
LGY76_RS13335	COG4215	(ABC) transporter
LGY76_RS13350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS13395	COG1131	(ABC) transporter
LGY76_RS13400	COG0842	Transport permease protein
LGY76_RS13415	COG0772	Belongs to the SEDS family
LGY76_RS13420	COG2951	lytic endotransglycosylase activity
LGY76_RS13445	COG2207	Transcriptional regulator
LGY76_RS13460	COG0052	Belongs to the universal ribosomal protein uS2 family
LGY76_RS13465	COG0024	Methionine aminopeptidase
LGY76_RS13475	COG2223	nitrite transmembrane transporter activity
LGY76_RS13485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGY76_RS13490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGY76_RS13495	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS13510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LGY76_RS13515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LGY76_RS13520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGY76_RS13540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGY76_RS13545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGY76_RS13550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGY76_RS13580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LGY76_RS13590	COG0174	glutamine synthetase
LGY76_RS13605	COG0512	Glutamine amidotransferase of anthranilate synthase
LGY76_RS13610	COG0308	aminopeptidase N
LGY76_RS13640	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LGY76_RS13650	COG0302	gtp cyclohydrolase
LGY76_RS13675	COG3739	integral membrane protein
LGY76_RS13690	COG1169	isochorismate synthase
LGY76_RS13700	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LGY76_RS13705	COG1132	(ABC) transporter
LGY76_RS13710	COG1132	(ABC) transporter
LGY76_RS13725	COG3433	isochorismatase activity
LGY76_RS13725	COG1535	isochorismatase
LGY76_RS13730	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGY76_RS13735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGY76_RS13745	COG4774	siderophore transport
LGY76_RS13750	COG4607	ABC-type enterochelin transport system periplasmic component
LGY76_RS13755	COG4604	ABC transporter, ATP-binding protein
LGY76_RS13760	COG4605	iron ion homeostasis
LGY76_RS13765	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGY76_RS13770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGY76_RS13785	COG2964	Protein conserved in bacteria
LGY76_RS13795	COG1741	Belongs to the pirin family
LGY76_RS13815	COG1309	transcriptional regulator
LGY76_RS13825	COG4948	Mandelate Racemase Muconate Lactonizing
LGY76_RS13830	COG2814	Major facilitator Superfamily
LGY76_RS13865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGY76_RS13865	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LGY76_RS13870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGY76_RS13880	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS13890	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGY76_RS13895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGY76_RS13900	COG0583	DNA-binding transcription factor activity
LGY76_RS13905	COG1113	amino acid transport
LGY76_RS13925	COG2508	Transcriptional regulator
LGY76_RS13925	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LGY76_RS13960	COG2879	small protein
LGY76_RS13965	COG1966	Carbon starvation protein
LGY76_RS14010	COG1067	ATP-dependent peptidase activity
LGY76_RS14015	COG0583	DNA-binding transcription factor activity
LGY76_RS14040	COG1686	Belongs to the peptidase S11 family
LGY76_RS14045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGY76_RS14075	COG3328	transposase activity
LGY76_RS14085	COG0616	signal peptide processing
LGY76_RS14090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LGY76_RS14100	COG0573	inorganic phosphate transmembrane transporter activity
LGY76_RS14105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGY76_RS14110	COG1113	amino acid transport
LGY76_RS14115	COG3961	Belongs to the TPP enzyme family
LGY76_RS14120	COG1522	sequence-specific DNA binding
LGY76_RS14130	COG0076	glutamate decarboxylase activity
LGY76_RS14135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGY76_RS14145	COG1309	transcriptional regulator
LGY76_RS14160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGY76_RS14195	COG0352	thiamine-phosphate diphosphorylase activity
LGY76_RS14220	COG0612	Peptidase, M16
LGY76_RS14240	COG1823	symporter activity
LGY76_RS14245	COG0583	DNA-binding transcription factor activity
LGY76_RS14250	COG0477	Major facilitator Superfamily
LGY76_RS14275	COG1187	pseudouridine synthase activity
LGY76_RS14295	COG1686	Belongs to the peptidase S11 family
LGY76_RS14300	COG1252	NADH dehydrogenase
LGY76_RS14310	COG0415	Belongs to the DNA photolyase family
LGY76_RS14325	COG1215	transferase activity, transferring glycosyl groups
LGY76_RS14355	COG2070	2-Nitropropane dioxygenase
LGY76_RS14410	COG0556	nucleotide-excision repair
LGY76_RS14430	COG0436	Aminotransferase
LGY76_RS14460	COG4221	oxidoreductase activity
LGY76_RS14470	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGY76_RS14475	COG1381	Involved in DNA repair and RecF pathway recombination
LGY76_RS14485	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGY76_RS14500	COG0681	Belongs to the peptidase S26 family
LGY76_RS14515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGY76_RS14535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGY76_RS14540	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGY76_RS14545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGY76_RS14555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGY76_RS14560	COG4208	sulfate ABC transporter
LGY76_RS14565	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LGY76_RS14570	COG0583	DNA-binding transcription factor activity
LGY76_RS14575	COG4625	pathogenesis
LGY76_RS14590	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGY76_RS14605	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGY76_RS14615	COG1051	belongs to the nudix hydrolase family
LGY76_RS14615	COG1056	cytidyltransferase-related domain
LGY76_RS14620	COG1024	Enoyl-CoA hydratase
LGY76_RS14630	COG2814	Major facilitator Superfamily
LGY76_RS14635	COG0047	phosphoribosylformylglycinamidine synthase activity
LGY76_RS14635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LGY76_RS14655	COG1473	amidohydrolase
LGY76_RS14660	COG0824	Thioesterase
LGY76_RS14680	COG0823	Involved in the tonB-independent uptake of proteins
LGY76_RS14700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGY76_RS14735	COG0628	permease
LGY76_RS14745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGY76_RS14750	COG0596	Alpha beta hydrolase
LGY76_RS14755	COG0616	signal peptide processing
LGY76_RS14755	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGY76_RS14770	COG1136	(ABC) transporter
LGY76_RS14775	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGY76_RS14810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS14830	COG0463	Glycosyl transferase, family 2
LGY76_RS14860	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGY76_RS14865	COG1280	lysine exporter protein (LysE YggA)
LGY76_RS14870	COG2267	carboxylic ester hydrolase activity
LGY76_RS14880	COG0019	diaminopimelate decarboxylase activity
LGY76_RS14890	COG1113	amino acid transport
LGY76_RS14895	COG1115	amino acid carrier protein
LGY76_RS14910	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGY76_RS14920	COG3339	Conserved Protein
LGY76_RS14925	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LGY76_RS14930	COG0243	molybdopterin cofactor binding
LGY76_RS14940	COG1929	Belongs to the glycerate kinase type-1 family
LGY76_RS14955	COG0778	Nitroreductase
LGY76_RS14970	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGY76_RS14985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGY76_RS15005	COG0741	lytic transglycosylase activity
LGY76_RS15025	COG0584	glycerophosphoryl diester phosphodiesterase
LGY76_RS15050	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGY76_RS15055	COG1597	lipid kinase activity
LGY76_RS15070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGY76_RS15075	COG0477	Major facilitator Superfamily
LGY76_RS15110	COG3328	transposase activity
LGY76_RS15135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGY76_RS15140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGY76_RS15165	COG0505	Belongs to the CarA family
LGY76_RS15185	COG0251	oxidation-reduction process
LGY76_RS15195	COG0589	response to stress
LGY76_RS15210	COG2843	Capsule synthesis protein
LGY76_RS15230	COG2321	neutral zinc metallopeptidase
LGY76_RS15235	COG2354	Protein conserved in bacteria
LGY76_RS15255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGY76_RS15280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGY76_RS15285	COG1053	succinate dehydrogenase
LGY76_RS15290	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGY76_RS15295	COG2009	succinate dehydrogenase
LGY76_RS15330	COG2921	Belongs to the UPF0250 family
LGY76_RS15335	COG0321	lipoyl(octanoyl) transferase activity
LGY76_RS15350	COG0531	amino acid
LGY76_RS15370	COG4372	Transposase
LGY76_RS15380	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGY76_RS15385	COG1648	precorrin-2 dehydrogenase activity
LGY76_RS15385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGY76_RS15400	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGY76_RS15430	COG0671	phosphoesterase, PA-phosphatase related
LGY76_RS15435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS15445	COG1538	Outer membrane efflux protein
LGY76_RS15450	COG0393	Putative heavy-metal-binding
LGY76_RS15455	COG0393	Putative heavy-metal-binding
LGY76_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS15475	COG0525	valine-tRNA ligase activity
LGY76_RS15480	COG2226	methyltransferase
LGY76_RS15485	COG3328	transposase activity
LGY76_RS15500	COG0583	DNA-binding transcription factor activity
LGY76_RS15505	COG0004	ammonium transporteR
LGY76_RS15515	COG0642	Histidine kinase
LGY76_RS15520	COG0745	RESPONSE REGULATOR receiver
LGY76_RS15525	COG2194	sulfuric ester hydrolase activity
LGY76_RS15545	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGY76_RS15560	COG2315	Protein conserved in bacteria
LGY76_RS15565	COG0142	geranyltranstransferase activity
LGY76_RS15570	COG2828	Protein conserved in bacteria
LGY76_RS15575	COG1113	amino acid transport
LGY76_RS15615	COG2207	Transcriptional regulator
LGY76_RS15640	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGY76_RS15650	COG0560	Phosphoserine phosphatase
LGY76_RS15660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGY76_RS15670	COG1530	ribonuclease E activity
LGY76_RS15675	COG0424	maF-like protein
LGY76_RS15680	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGY76_RS15685	COG1792	Involved in formation and maintenance of cell shape
LGY76_RS15690	COG1077	Cell shape determining protein MreB Mrl
LGY76_RS15695	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGY76_RS15705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LGY76_RS15745	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LGY76_RS15750	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LGY76_RS15755	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGY76_RS15760	COG1115	amino acid carrier protein
LGY76_RS15780	COG2814	Major facilitator Superfamily
LGY76_RS15785	COG1289	transmembrane transporter activity
LGY76_RS15795	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGY76_RS15835	COG1376	ErfK ybiS ycfS ynhG family protein
LGY76_RS15840	COG2832	Protein of unknown function (DUF454)
LGY76_RS15850	COG5510	response to toxic substance
LGY76_RS15870	COG0840	transmembrane signaling receptor activity
LGY76_RS15910	COG3422	double-strand break repair
LGY76_RS15915	COG2824	Alkylphosphonate utilization operon protein PhnA
LGY76_RS15920	COG3189	MarR family transcriptional regulator
LGY76_RS15930	COG0354	folic acid binding
LGY76_RS15935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGY76_RS15945	COG0679	Auxin Efflux Carrier
LGY76_RS15950	COG1902	pentaerythritol trinitrate reductase activity
LGY76_RS15970	COG2094	Belongs to the DNA glycosylase MPG family
LGY76_RS15995	COG1217	gtp-binding protein TYPA
LGY76_RS16000	COG2233	PERMEase
LGY76_RS16010	COG0833	amino acid
LGY76_RS16015	COG1690	Belongs to the RtcB family
LGY76_RS16025	COG2885	chlorophyll binding
LGY76_RS16025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGY76_RS16035	COG0183	Belongs to the thiolase family
LGY76_RS16055	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGY76_RS16075	COG2207	Transcriptional regulator
LGY76_RS16080	COG0183	Belongs to the thiolase family
LGY76_RS16110	COG1272	protein, Hemolysin III
LGY76_RS16115	COG0477	Major facilitator Superfamily
LGY76_RS16130	COG0450	alkyl hydroperoxide reductase
LGY76_RS16150	COG0285	dihydrofolate synthase activity
LGY76_RS16200	COG2096	Adenosyltransferase
LGY76_RS16220	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LGY76_RS16225	COG0745	RESPONSE REGULATOR receiver
LGY76_RS16230	COG2205	protein histidine kinase activity
LGY76_RS16240	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS16245	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS16250	COG0583	DNA-binding transcription factor activity
LGY76_RS16255	COG0625	glutathione transferase activity
LGY76_RS16320	COG0438	transferase activity, transferring glycosyl groups
LGY76_RS16325	COG0463	Glycosyl transferase, family 2
LGY76_RS16330	COG0726	polysaccharide deacetylase
LGY76_RS16350	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LGY76_RS16355	COG2205	protein histidine kinase activity
LGY76_RS16385	COG1862	Preprotein translocase
LGY76_RS16395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGY76_RS16400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGY76_RS16410	COG3781	membrane
LGY76_RS16415	COG0613	PHP domain protein
LGY76_RS16425	COG2350	Protein conserved in bacteria
LGY76_RS16455	COG1607	acyl-coa hydrolase
LGY76_RS16515	COG2199	diguanylate cyclase activity
LGY76_RS16525	COG1408	metallophosphoesterase
LGY76_RS16530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGY76_RS16540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGY76_RS16560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LGY76_RS16565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGY76_RS16580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGY76_RS16590	COG2969	positive regulation of protein catabolic process
LGY76_RS16610	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS16615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LGY76_RS16630	COG1309	transcriptional regulator
LGY76_RS16635	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS16680	COG1183	phosphatidylcholine synthase activity
LGY76_RS16685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGY76_RS16715	COG0741	lytic transglycosylase activity
LGY76_RS16715	COG1196	nuclear chromosome segregation
LGY76_RS16715	COG0739	heme binding
LGY76_RS16725	COG1702	phosphate starvation-inducible protein PhoH
LGY76_RS16760	COG1295	ribonuclease BN
LGY76_RS16765	COG0697	spore germination
LGY76_RS16770	COG2169	Transcriptional regulator
LGY76_RS16775	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGY76_RS16820	COG0557	exoribonuclease II activity
LGY76_RS16825	COG0339	signal peptide processing
LGY76_RS16830	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGY76_RS16860	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGY76_RS16865	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS17020	COG0626	cystathionine gamma-synthase activity
LGY76_RS17025	COG0433	COG0433 Predicted ATPase
LGY76_RS17030	COG1017	nitric oxide dioxygenase activity
LGY76_RS17030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGY76_RS17035	COG1959	2 iron, 2 sulfur cluster binding
LGY76_RS17050	COG1301	dicarboxylic acid transport
LGY76_RS17055	COG1946	Acyl-CoA thioesterase
LGY76_RS17075	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGY76_RS17080	COG1040	competence protein
LGY76_RS17085	COG0494	nUDIX hydrolase
LGY76_RS17095	COG0598	Magnesium transport protein CorA
LGY76_RS17105	COG2854	intermembrane phospholipid transfer
LGY76_RS17115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGY76_RS17120	COG1127	ABC transporter
LGY76_RS17130	COG0513	Belongs to the DEAD box helicase family
LGY76_RS17150	COG0408	coproporphyrinogen oxidase activity
LGY76_RS17165	COG1960	acyl-CoA dehydrogenase activity
LGY76_RS17175	COG1983	PspC domain protein
LGY76_RS17180	COG0517	IMP dehydrogenase activity
LGY76_RS17225	COG0583	DNA-binding transcription factor activity
LGY76_RS17265	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS17275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGY76_RS17280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LGY76_RS17285	COG0833	amino acid
LGY76_RS17315	COG1192	Involved in chromosome partitioning
LGY76_RS17320	COG0628	permease
LGY76_RS17330	COG1289	transmembrane transporter activity
LGY76_RS17345	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGY76_RS17350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGY76_RS17360	COG0277	FAD linked oxidase domain protein
LGY76_RS17365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGY76_RS17390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LGY76_RS17395	COG5380	lipid catabolic process
LGY76_RS17415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGY76_RS17485	COG0194	GDP metabolic process
LGY76_RS17500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGY76_RS17520	COG3307	-O-antigen
LGY76_RS17540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LGY76_RS17545	COG1704	LemA family
LGY76_RS17555	COG0493	'glutamate synthase
LGY76_RS17560	COG0070	glutamate synthase
LGY76_RS17560	COG0069	glutamate synthase activity
LGY76_RS17560	COG0067	glutamate synthase
LGY76_RS17610	COG2226	methyltransferase
LGY76_RS17625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGY76_RS17630	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGY76_RS17675	COG0833	amino acid
LGY76_RS17760	COG0488	(ABC) transporter
LGY76_RS17765	COG2873	o-acetylhomoserine
LGY76_RS17770	COG4221	oxidoreductase activity
LGY76_RS17775	COG0659	secondary active sulfate transmembrane transporter activity
LGY76_RS17800	COG0427	acetyl-CoA hydrolase
LGY76_RS17830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGY76_RS17860	COG2329	Antibiotic biosynthesis monooxygenase
LGY76_RS17875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGY76_RS17940	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGY76_RS17945	COG1733	regulation of RNA biosynthetic process
LGY76_RS17980	COG0667	Aldo Keto reductase
LGY76_RS18000	COG0583	DNA-binding transcription factor activity
LGY76_RS18005	COG2814	Major facilitator Superfamily
LGY76_RS18035	COG1335	isochorismatase
LGY76_RS18045	COG1012	belongs to the aldehyde dehydrogenase family
LGY76_RS18050	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LGY76_RS18060	COG1113	amino acid transport
LGY76_RS18070	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LGY76_RS18085	COG2814	Major facilitator Superfamily
LGY76_RS18095	COG0352	thiamine-phosphate diphosphorylase activity
LGY76_RS18095	COG0351	phosphomethylpyrimidine kinase
LGY76_RS18095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LGY76_RS18115	COG1309	transcriptional regulator
LGY76_RS18120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGY76_RS18140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LGY76_RS18150	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGY76_RS18155	COG3162	membrane
LGY76_RS18160	COG0784	Response regulator, receiver
LGY76_RS18160	COG2198	Histidine kinase
LGY76_RS18160	COG2205	protein histidine kinase activity
LGY76_RS18185	COG3328	transposase activity
LGY76_RS18190	COG1522	sequence-specific DNA binding
LGY76_RS18195	COG1335	isochorismatase
LGY76_RS18200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGY76_RS18210	COG0668	transmembrane transport
LGY76_RS18215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGY76_RS18220	COG1519	Transferase
LGY76_RS18225	COG1902	pentaerythritol trinitrate reductase activity
LGY76_RS18245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGY76_RS18270	COG0426	domain, Protein
LGY76_RS18270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LGY76_RS18275	COG4774	siderophore transport
LGY76_RS18280	COG2119	membrane
LGY76_RS18290	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGY76_RS18300	COG4942	peptidase
LGY76_RS18315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGY76_RS18325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGY76_RS18345	COG0189	ligase activity
LGY76_RS18365	COG0708	Exodeoxyribonuclease III
LGY76_RS18370	COG1393	Belongs to the ArsC family
LGY76_RS18385	COG3706	GGDEF domain
LGY76_RS18420	COG2351	hydroxyisourate hydrolase activity
LGY76_RS18425	COG2233	PERMEase
LGY76_RS18435	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGY76_RS18445	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LGY76_RS18450	COG1028	Short-chain dehydrogenase reductase Sdr
LGY76_RS18460	COG3150	esterase
LGY76_RS18475	COG1388	LysM domain
LGY76_RS18475	COG0791	NLP P60 protein
LGY76_RS18490	COG2918	glutathione biosynthetic process
LGY76_RS18505	COG2733	membrane
LGY76_RS18510	COG0436	Aminotransferase
LGY76_RS18515	COG0534	Mate efflux family protein
LGY76_RS18615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGY76_RS18620	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGY76_RS18630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LGY76_RS18635	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LGY76_RS18650	COG0010	Belongs to the arginase family
LGY76_RS18680	COG2188	Transcriptional regulator
LGY76_RS18690	COG0523	cobalamin synthesis protein
LGY76_RS18700	COG1113	amino acid transport
LGY76_RS18710	COG0625	glutathione transferase activity
LGY76_RS18730	COG1683	Conserved Protein
LGY76_RS18735	COG0534	Mate efflux family protein
LGY76_RS18740	COG0385	Bile acid
LGY76_RS18745	COG1335	isochorismatase
LGY76_RS18750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGY76_RS18770	COG2116	formate transmembrane transporter activity
LGY76_RS18775	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGY76_RS18780	COG2133	pyrroloquinoline quinone binding
LGY76_RS18785	COG2983	Belongs to the UPF0260 family
LGY76_RS18805	COG1194	a g-specific adenine glycosylase
LGY76_RS18820	COG2818	Glycosylase
LGY76_RS18825	COG1064	alcohol dehydrogenase
LGY76_RS18830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGY76_RS18845	COG0583	DNA-binding transcription factor activity
LGY76_RS18850	COG0656	L-ascorbic acid biosynthetic process
LGY76_RS18855	COG2814	Major facilitator Superfamily
LGY76_RS18890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGY76_RS18905	COG2233	PERMEase
LGY76_RS18945	COG0733	neurotransmitter:sodium symporter activity
LGY76_RS18985	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGY76_RS18990	COG0657	acetylesterase activity
LGY76_RS19010	COG0583	DNA-binding transcription factor activity
LGY76_RS19040	COG2951	lytic endotransglycosylase activity
LGY76_RS19045	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGY76_RS19060	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGY76_RS19070	COG0671	phosphoesterase, PA-phosphatase related
LGY76_RS19075	COG0861	Integral membrane protein TerC family
LGY76_RS19085	COG0754	glutathionylspermidine amidase activity
LGY76_RS19095	COG0402	S-adenosylhomocysteine deaminase activity
LGY76_RS19115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGY76_RS19120	COG1230	cation diffusion facilitator family transporter
LGY76_RS19135	COG0706	membrane insertase activity
LGY76_RS19240	COG0741	lytic transglycosylase activity
LGY76_RS19275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGY76_RS19355	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGY76_RS19425	COG1525	nuclease
LGY76_RS19485	COG1475	DNA binding
LGY76_RS19500	COG3853	Toxic anion resistance protein (TelA)
LGY76_RS19585	COG0484	heat shock protein binding
LGY76_RS19645	COG2826	transposase and inactivated derivatives, IS30 family
LGY76_RS19655	COG2826	transposase and inactivated derivatives, IS30 family
LGY76_RS19685	COG0741	lytic transglycosylase activity
LGY76_RS19720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process