locus-tag	class	description
AXK18_RS00030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXK18_RS00045	COG0506	proline dehydrogenase activity
AXK18_RS00045	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXK18_RS00045	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXK18_RS00050	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AXK18_RS00065	COG3698	Phosphodiester glycosidase
AXK18_RS00075	COG2353	YceI-like domain
AXK18_RS00085	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AXK18_RS00130	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AXK18_RS00130	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AXK18_RS00155	COG3539	Fimbrial protein
AXK18_RS00160	COG3121	Chaperone
AXK18_RS00185	COG0697	spore germination
AXK18_RS00195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXK18_RS00205	COG0583	DNA-binding transcription factor activity
AXK18_RS00230	COG1309	transcriptional regulator
AXK18_RS00245	COG1522	sequence-specific DNA binding
AXK18_RS00255	COG1126	abc transporter atp-binding protein
AXK18_RS00260	COG0765	amino acid transport
AXK18_RS00265	COG0765	amino acid transport
AXK18_RS00295	COG1464	Belongs to the NlpA lipoprotein family
AXK18_RS00305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXK18_RS00310	COG2011	ABC-type metal ion transport system permease component
AXK18_RS00315	COG0012	GTP binding
AXK18_RS00340	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXK18_RS00380	COG0386	Belongs to the glutathione peroxidase family
AXK18_RS00390	COG0436	Aminotransferase
AXK18_RS00430	COG3634	alkyl hydroperoxide reductase activity
AXK18_RS00445	COG0583	DNA-binding transcription factor activity
AXK18_RS00450	COG0798	PFAM Bile acid sodium symporter
AXK18_RS00455	COG0640	Transcriptional regulator
AXK18_RS00470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AXK18_RS00490	COG1953	Uracil, thiamine, allantoin
AXK18_RS00500	COG2175	clavaminate synthase activity
AXK18_RS00505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK18_RS00510	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AXK18_RS00515	COG4521	taurine ABC transporter
AXK18_RS00525	COG0477	Major facilitator Superfamily
AXK18_RS00550	COG1271	oxidase subunit
AXK18_RS00555	COG1294	oxidase, subunit
AXK18_RS00565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK18_RS00585	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AXK18_RS00610	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AXK18_RS00620	COG2814	Major facilitator Superfamily
AXK18_RS00640	COG1346	cytolysis
AXK18_RS00650	COG0583	DNA-binding transcription factor activity
AXK18_RS00655	COG0625	glutathione transferase activity
AXK18_RS00660	COG0625	glutathione transferase activity
AXK18_RS00665	COG0583	DNA-binding transcription factor activity
AXK18_RS00680	COG1045	serine acetyltransferase
AXK18_RS00685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AXK18_RS00690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AXK18_RS00700	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS00715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK18_RS00720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK18_RS00725	COG1126	abc transporter atp-binding protein
AXK18_RS00730	COG0765	amino acid transport
AXK18_RS00735	COG0765	amino acid transport
AXK18_RS00755	COG2205	protein histidine kinase activity
AXK18_RS00755	COG0784	Response regulator, receiver
AXK18_RS00775	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AXK18_RS00795	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS00840	COG0583	DNA-binding transcription factor activity
AXK18_RS00860	COG0318	PFAM AMP-dependent synthetase and ligase
AXK18_RS00865	COG1309	transcriptional regulator
AXK18_RS00870	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS00875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXK18_RS00880	COG1024	Enoyl-CoA hydratase
AXK18_RS00885	COG4770	biotin carboxylase activity
AXK18_RS00910	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS00920	COG2814	Major facilitator Superfamily
AXK18_RS00930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK18_RS00935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXK18_RS00940	COG2814	Major facilitator Superfamily
AXK18_RS00945	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS00950	COG1024	Enoyl-CoA hydratase
AXK18_RS00955	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS00960	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXK18_RS00965	COG0183	Belongs to the thiolase family
AXK18_RS00975	COG2814	Major facilitator Superfamily
AXK18_RS00985	COG1024	Enoyl-CoA hydratase
AXK18_RS01005	COG2814	Major facilitator Superfamily
AXK18_RS01010	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AXK18_RS01015	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AXK18_RS01030	COG3842	ATPase activity
AXK18_RS01035	COG1840	ABC-type Fe3 transport system, periplasmic component
AXK18_RS01045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK18_RS01050	COG1414	Transcriptional regulator
AXK18_RS01060	COG0583	DNA-binding transcription factor activity
AXK18_RS01065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK18_RS01070	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS01080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AXK18_RS01090	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS01095	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK18_RS01100	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK18_RS01105	COG2267	carboxylic ester hydrolase activity
AXK18_RS01125	COG3038	cytochrome b561
AXK18_RS01130	COG0753	catalase activity
AXK18_RS01170	COG2050	protein possibly involved in aromatic compounds catabolism
AXK18_RS01180	COG3327	negative regulation of DNA-templated transcription, initiation
AXK18_RS01185	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AXK18_RS01190	COG0183	Belongs to the thiolase family
AXK18_RS01195	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXK18_RS01200	COG1024	Enoyl-CoA hydratase
AXK18_RS01205	COG1024	Enoyl-CoA hydratase
AXK18_RS01210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK18_RS01215	COG2151	metal-sulfur cluster biosynthetic enzyme
AXK18_RS01220	COG3396	Phenylacetate-CoA oxygenase
AXK18_RS01225	COG3460	Phenylacetate-CoA oxygenase
AXK18_RS01230	COG3396	Phenylacetate-CoA oxygenase
AXK18_RS01235	COG2030	dehydratase
AXK18_RS01235	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS01240	COG1760	l-serine dehydratase
AXK18_RS01245	COG0531	amino acid
AXK18_RS01250	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS01265	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK18_RS01295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK18_RS01310	COG0789	Transcriptional regulator
AXK18_RS01325	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AXK18_RS01340	COG2807	transmembrane transport
AXK18_RS01345	COG0590	tRNA wobble adenosine to inosine editing
AXK18_RS01465	COG1116	anion transmembrane transporter activity
AXK18_RS01470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AXK18_RS01480	COG0864	Transcriptional regulator
AXK18_RS01500	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXK18_RS01505	COG0439	Biotin carboxylase
AXK18_RS01520	COG1063	alcohol dehydrogenase
AXK18_RS01530	COG1309	transcriptional regulator
AXK18_RS01555	COG0038	chloride channel
AXK18_RS01560	COG4770	biotin carboxylase activity
AXK18_RS01580	COG1914	H( )-stimulated, divalent metal cation uptake system
AXK18_RS01585	COG0583	DNA-binding transcription factor activity
AXK18_RS01640	COG1250	3-hydroxyacyl-CoA dehydrogenase
AXK18_RS01675	COG1560	Kdo2-lipid A biosynthetic process
AXK18_RS01685	COG5006	permease, DMT superfamily
AXK18_RS01690	COG1522	sequence-specific DNA binding
AXK18_RS01705	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AXK18_RS01715	COG4122	O-methyltransferase activity
AXK18_RS01745	COG1538	Outer membrane efflux protein
AXK18_RS01750	COG1137	ATPase activity
AXK18_RS01755	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AXK18_RS01765	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AXK18_RS01770	COG0517	IMP dehydrogenase activity
AXK18_RS01770	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AXK18_RS01810	COG2814	Major facilitator Superfamily
AXK18_RS01850	COG1278	Cold shock
AXK18_RS01855	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS01890	COG1570	exodeoxyribonuclease VII activity
AXK18_RS01945	COG0583	DNA-binding transcription factor activity
AXK18_RS01950	COG4638	Rieske (2fe-2S)
AXK18_RS01955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXK18_RS01960	COG0633	Ferredoxin
AXK18_RS01960	COG0543	2 iron, 2 sulfur cluster binding
AXK18_RS01965	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS01970	COG3135	benzoate transporter
AXK18_RS01975	COG2814	Major facilitator Superfamily
AXK18_RS01990	COG1643	Atp-dependent helicase
AXK18_RS01995	COG0450	alkyl hydroperoxide reductase
AXK18_RS02005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AXK18_RS02015	COG3634	alkyl hydroperoxide reductase activity
AXK18_RS02035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AXK18_RS02040	COG0625	glutathione transferase activity
AXK18_RS02050	COG2885	chlorophyll binding
AXK18_RS02085	COG0542	response to heat
AXK18_RS02100	COG1765	OsmC-like protein
AXK18_RS02115	COG0667	Aldo Keto reductase
AXK18_RS02130	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AXK18_RS02140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AXK18_RS02150	COG0527	aspartate kinase activity
AXK18_RS02160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AXK18_RS02170	COG3038	cytochrome b561
AXK18_RS02175	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AXK18_RS02180	COG2252	PERMEase
AXK18_RS02190	COG2072	flavoprotein involved in K transport
AXK18_RS02205	COG1741	Belongs to the pirin family
AXK18_RS02210	COG1309	transcriptional regulator
AXK18_RS02240	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AXK18_RS02290	COG1902	pentaerythritol trinitrate reductase activity
AXK18_RS02290	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK18_RS02300	COG5001	Diguanylate cyclase
AXK18_RS02300	COG4251	negative regulation of phosphorylation
AXK18_RS02300	COG3706	GGDEF domain
AXK18_RS02300	COG2203	Gaf domain
AXK18_RS02310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK18_RS02330	COG4172	Belongs to the ABC transporter superfamily
AXK18_RS02335	COG4239	(ABC) transporter, permease
AXK18_RS02340	COG4174	ABC transporter (Permease)
AXK18_RS02350	COG1388	LysM domain
AXK18_RS02350	COG0741	lytic transglycosylase activity
AXK18_RS02350	COG1388	LysM domain
AXK18_RS02350	COG0741	lytic transglycosylase activity
AXK18_RS02355	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK18_RS02395	COG0583	DNA-binding transcription factor activity
AXK18_RS02400	COG1279	arginine transmembrane transporter activity
AXK18_RS02420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK18_RS02425	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK18_RS02430	COG0006	proline dipeptidase activity
AXK18_RS02465	COG2194	sulfuric ester hydrolase activity
AXK18_RS02510	COG0739	heme binding
AXK18_RS02835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AXK18_RS02860	COG3384	dioxygenase
AXK18_RS02870	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXK18_RS02875	COG2878	Part of a membrane complex involved in electron transport
AXK18_RS02880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AXK18_RS02905	COG0768	penicillin binding
AXK18_RS02910	COG0742	ribosomal rna small subunit methyltransferase
AXK18_RS02925	COG0830	nickel cation binding
AXK18_RS02975	COG1253	flavin adenine dinucleotide binding
AXK18_RS02985	COG2851	Citrate transporter
AXK18_RS03040	COG1773	rubredoxin
AXK18_RS03045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK18_RS03055	COG0583	DNA-binding transcription factor activity
AXK18_RS03080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AXK18_RS03085	COG4181	ATPase activity
AXK18_RS03130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AXK18_RS03150	COG0306	phosphate transporter
AXK18_RS03160	COG3958	Transketolase
AXK18_RS03165	COG3959	Transketolase, thiamine diphosphate binding domain
AXK18_RS03170	COG2271	Major facilitator Superfamily
AXK18_RS03175	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS03180	COG0583	DNA-binding transcription factor activity
AXK18_RS03200	COG2223	nitrite transmembrane transporter activity
AXK18_RS03205	COG2207	Transcriptional regulator
AXK18_RS03210	COG2066	Belongs to the glutaminase family
AXK18_RS03215	COG0242	peptide deformylase activity
AXK18_RS03220	COG0477	Major facilitator Superfamily
AXK18_RS03230	COG0028	Belongs to the TPP enzyme family
AXK18_RS03245	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS03250	COG2267	carboxylic ester hydrolase activity
AXK18_RS03275	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS03295	COG1414	Transcriptional regulator
AXK18_RS03310	COG1024	Enoyl-CoA hydratase
AXK18_RS03320	COG1215	transferase activity, transferring glycosyl groups
AXK18_RS03335	COG4681	YaeQ
AXK18_RS03345	COG0523	cobalamin synthesis protein
AXK18_RS03355	COG1607	acyl-coa hydrolase
AXK18_RS03365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK18_RS03370	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK18_RS03375	COG1309	transcriptional regulator
AXK18_RS03400	COG2040	homocysteine
AXK18_RS03405	COG0531	amino acid
AXK18_RS03460	COG1595	DNA-templated transcription, initiation
AXK18_RS03470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK18_RS03475	COG0477	Major facilitator Superfamily
AXK18_RS03495	COG0084	hydrolase, TatD family'
AXK18_RS03585	COG0582	viral genome integration into host DNA
AXK18_RS03680	COG0592	DNA-directed DNA polymerase activity
AXK18_RS03720	COG2026	Addiction module toxin, RelE StbE family
AXK18_RS03915	COG1484	DNA-dependent DNA replication
AXK18_RS04005	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AXK18_RS04070	COG0405	Gamma-glutamyltransferase
AXK18_RS04075	COG2814	Major facilitator Superfamily
AXK18_RS04085	COG2050	protein possibly involved in aromatic compounds catabolism
AXK18_RS04100	COG1090	epimerase
AXK18_RS04120	COG0420	3'-5' exonuclease activity
AXK18_RS04145	COG0735	belongs to the Fur family
AXK18_RS04150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AXK18_RS04175	COG0121	glutamine amidotransferase
AXK18_RS04190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXK18_RS04200	COG0210	DNA helicase
AXK18_RS04210	COG0204	Acyl-transferase
AXK18_RS04225	COG2894	cell division
AXK18_RS04245	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS04255	COG0492	ferredoxin-NADP+ reductase activity
AXK18_RS04260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AXK18_RS04270	COG0456	acetyltransferase
AXK18_RS04315	COG1981	membrane
AXK18_RS04330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXK18_RS04330	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AXK18_RS04350	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS04360	COG0657	acetylesterase activity
AXK18_RS04370	COG0473	3-isopropylmalate dehydrogenase activity
AXK18_RS04375	COG0583	DNA-binding transcription factor activity
AXK18_RS04395	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK18_RS04420	COG0564	pseudouridine synthase activity
AXK18_RS04430	COG0358	DNA primase activity
AXK18_RS04445	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AXK18_RS04475	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXK18_RS04505	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AXK18_RS04515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXK18_RS04515	COG0352	thiamine-phosphate diphosphorylase activity
AXK18_RS04515	COG0351	phosphomethylpyrimidine kinase
AXK18_RS04520	COG1652	LysM domain
AXK18_RS04545	COG1399	metal-binding, possibly nucleic acid-binding protein
AXK18_RS04550	COG3101	peptidyl-lysine hydroxylation
AXK18_RS04555	COG0009	L-threonylcarbamoyladenylate synthase
AXK18_RS04560	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AXK18_RS04565	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AXK18_RS04580	COG4106	trans-aconitate 2-methyltransferase activity
AXK18_RS04595	COG2226	methyltransferase
AXK18_RS04595	COG0596	Alpha beta hydrolase
AXK18_RS04595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXK18_RS04600	COG1877	trehalose-phosphatase activity
AXK18_RS04605	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AXK18_RS04610	COG2223	nitrite transmembrane transporter activity
AXK18_RS04630	COG1196	nuclear chromosome segregation
AXK18_RS04640	COG0730	response to heat
AXK18_RS04655	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AXK18_RS04665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXK18_RS04730	COG0489	protein tyrosine kinase activity
AXK18_RS04740	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK18_RS04740	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK18_RS04770	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AXK18_RS04775	COG2081	HI0933 family
AXK18_RS04785	COG0668	transmembrane transport
AXK18_RS04805	COG0583	DNA-binding transcription factor activity
AXK18_RS04825	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AXK18_RS04830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXK18_RS04860	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AXK18_RS04900	COG0745	RESPONSE REGULATOR receiver
AXK18_RS04920	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AXK18_RS05000	COG4993	Dehydrogenase
AXK18_RS05020	COG0384	phenazine biosynthesis protein PhzF
AXK18_RS05050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK18_RS05065	COG0583	DNA-binding transcription factor activity
AXK18_RS05095	COG0583	DNA-binding transcription factor activity
AXK18_RS05130	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AXK18_RS05140	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS05145	COG0583	DNA-binding transcription factor activity
AXK18_RS05150	COG1063	alcohol dehydrogenase
AXK18_RS05180	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AXK18_RS05185	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AXK18_RS05190	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXK18_RS05205	COG3667	copper resistance
AXK18_RS05210	COG2132	Multicopper oxidase
AXK18_RS05220	COG0561	phosphatase activity
AXK18_RS05225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AXK18_RS05250	COG1214	PFAM Peptidase M22, glycoprotease
AXK18_RS05300	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AXK18_RS05310	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AXK18_RS05315	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AXK18_RS05320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AXK18_RS05380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AXK18_RS05390	COG1846	Transcriptional regulator
AXK18_RS05395	COG1764	response to oxidative stress
AXK18_RS05445	COG0037	tRNA processing
AXK18_RS05455	COG0248	Ppx GppA phosphatase
AXK18_RS05485	COG0072	phenylalanine-tRNA ligase activity
AXK18_RS05525	COG1238	metal cluster binding
AXK18_RS05530	COG0625	glutathione transferase activity
AXK18_RS05550	COG0318	PFAM AMP-dependent synthetase and ligase
AXK18_RS05555	COG3028	Belongs to the UPF0307 family
AXK18_RS05560	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK18_RS05580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AXK18_RS05585	COG0617	tRNA 3'-terminal CCA addition
AXK18_RS05590	COG1555	photosystem II stabilization
AXK18_RS05595	COG3956	TIGRFAM MazG family protein
AXK18_RS05605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXK18_RS05630	COG1024	Enoyl-CoA hydratase
AXK18_RS05635	COG2084	Dehydrogenase
AXK18_RS05640	COG3622	Belongs to the hyi family
AXK18_RS05670	COG0697	spore germination
AXK18_RS05680	COG2814	Major facilitator Superfamily
AXK18_RS05685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AXK18_RS05695	COG0583	DNA-binding transcription factor activity
AXK18_RS05705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AXK18_RS05720	COG0084	hydrolase, TatD family'
AXK18_RS05735	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AXK18_RS05770	COG0440	acetolactate synthase activity
AXK18_RS05775	COG0028	Belongs to the TPP enzyme family
AXK18_RS05800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS05805	COG1136	(ABC) transporter
AXK18_RS05805	COG0577	efflux transmembrane transporter activity
AXK18_RS05810	COG1538	Outer membrane efflux protein
AXK18_RS05825	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AXK18_RS05830	COG1162	GTPase activity
AXK18_RS05840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AXK18_RS05860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AXK18_RS05865	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS05905	COG2986	histidine ammonia-lyase
AXK18_RS05920	COG0318	PFAM AMP-dependent synthetase and ligase
AXK18_RS05930	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXK18_RS05975	COG1426	Protein conserved in bacteria
AXK18_RS06020	COG0793	Belongs to the peptidase S41A family
AXK18_RS06035	COG2267	carboxylic ester hydrolase activity
AXK18_RS06045	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS06050	COG3265	gluconokinase activity
AXK18_RS06060	COG0800	Aldolase
AXK18_RS06075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AXK18_RS06080	COG0280	phosphate acetyltransferase
AXK18_RS06080	COG0857	belongs to the CobB CobQ family
AXK18_RS06085	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK18_RS06085	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AXK18_RS06105	COG0740	serine-type endopeptidase activity
AXK18_RS06115	COG4774	siderophore transport
AXK18_RS06125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AXK18_RS06135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXK18_RS06135	COG2813	Specifically methylates the guanine in position
AXK18_RS06235	COG0788	formyltetrahydrofolate deformylase activity
AXK18_RS06260	COG4651	solute:proton antiporter activity
AXK18_RS06260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXK18_RS06280	COG0724	RNA recognition motif
AXK18_RS06285	COG0210	DNA helicase
AXK18_RS06310	COG1733	regulation of RNA biosynthetic process
AXK18_RS06320	COG2900	Belongs to the SlyX family
AXK18_RS06325	COG0488	(ABC) transporter
AXK18_RS06330	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS06335	COG1560	Kdo2-lipid A biosynthetic process
AXK18_RS06345	COG1301	dicarboxylic acid transport
AXK18_RS06400	COG0473	3-isopropylmalate dehydrogenase activity
AXK18_RS06465	COG0583	DNA-binding transcription factor activity
AXK18_RS06475	COG0625	glutathione transferase activity
AXK18_RS06480	COG2378	regulation of single-species biofilm formation
AXK18_RS06485	COG0546	phosphoglycolate phosphatase activity
AXK18_RS06500	COG1530	ribonuclease E activity
AXK18_RS06505	COG0318	PFAM AMP-dependent synthetase and ligase
AXK18_RS06520	COG0583	DNA-binding transcription factor activity
AXK18_RS06525	COG4221	oxidoreductase activity
AXK18_RS06530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AXK18_RS06540	COG0534	Mate efflux family protein
AXK18_RS06555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AXK18_RS06595	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AXK18_RS06600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXK18_RS06625	COG0644	oxidoreductase
AXK18_RS06625	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AXK18_RS06630	COG0425	Belongs to the sulfur carrier protein TusA family
AXK18_RS06635	COG4535	Mg2 and Co2 transporter CorC
AXK18_RS06645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AXK18_RS06665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AXK18_RS06670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXK18_RS06670	COG0475	glutathione-regulated potassium exporter activity
AXK18_RS06675	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AXK18_RS06685	COG0484	heat shock protein binding
AXK18_RS06690	COG0789	Transcriptional regulator
AXK18_RS06695	COG0598	Magnesium transport protein CorA
AXK18_RS06710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXK18_RS06715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXK18_RS06720	COG1074	ATP-dependent DNA helicase activity
AXK18_RS06745	COG2226	methyltransferase
AXK18_RS06760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK18_RS06765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AXK18_RS06780	COG2111	Na H antiporter
AXK18_RS06780	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AXK18_RS06785	COG1006	Multisubunit Na H antiporter MnhC subunit
AXK18_RS06790	COG0651	ATP synthesis coupled electron transport
AXK18_RS06795	COG1863	multisubunit Na H antiporter MnhE subunit
AXK18_RS06800	COG2212	antiporter activity
AXK18_RS06805	COG1320	monovalent cation:proton antiporter activity
AXK18_RS06820	COG0195	Participates in both transcription termination and antitermination
AXK18_RS06870	COG0237	dephospho-CoA kinase activity
AXK18_RS06880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK18_RS06895	COG0497	DNA recombination
AXK18_RS06905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AXK18_RS06935	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AXK18_RS06935	COG2169	Transcriptional regulator
AXK18_RS06940	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AXK18_RS07025	COG0326	Molecular chaperone. Has ATPase activity
AXK18_RS07040	COG2056	Na+-H+ antiporter family
AXK18_RS07045	COG0596	Alpha beta hydrolase
AXK18_RS07140	COG0546	phosphoglycolate phosphatase activity
AXK18_RS07145	COG1716	ATPase activity
AXK18_RS07190	COG0181	hydroxymethylbilane synthase activity
AXK18_RS07200	COG3275	phosphorelay sensor kinase activity
AXK18_RS07220	COG1538	Outer membrane efflux protein
AXK18_RS07225	COG0697	spore germination
AXK18_RS07250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXK18_RS07255	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AXK18_RS07260	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXK18_RS07265	COG0772	Belongs to the SEDS family
AXK18_RS07290	COG4974	Belongs to the 'phage' integrase family
AXK18_RS07295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK18_RS07305	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AXK18_RS07315	COG2197	response regulator
AXK18_RS07330	COG0793	Belongs to the peptidase S41A family
AXK18_RS07335	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AXK18_RS07340	COG0795	lipopolysaccharide-transporting ATPase activity
AXK18_RS07380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXK18_RS07380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AXK18_RS07390	COG0004	ammonium transporteR
AXK18_RS07395	COG0347	Belongs to the P(II) protein family
AXK18_RS07405	COG0606	chelatase, subunit chli
AXK18_RS07475	COG1061	Type III restriction enzyme res subunit
AXK18_RS07490	COG0659	secondary active sulfate transmembrane transporter activity
AXK18_RS07495	COG0589	response to stress
AXK18_RS07540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXK18_RS07590	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXK18_RS07635	COG1061	Type III restriction enzyme res subunit
AXK18_RS07650	COG0659	secondary active sulfate transmembrane transporter activity
AXK18_RS07655	COG0589	response to stress
AXK18_RS07685	COG0606	chelatase, subunit chli
AXK18_RS07700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK18_RS07715	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AXK18_RS07730	COG0318	PFAM AMP-dependent synthetase and ligase
AXK18_RS07740	COG0477	Major facilitator Superfamily
AXK18_RS07745	COG2860	membrane
AXK18_RS07755	COG1253	flavin adenine dinucleotide binding
AXK18_RS07775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXK18_RS07810	COG0655	NAD(P)H dehydrogenase (quinone) activity
AXK18_RS07820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AXK18_RS07855	COG1309	transcriptional regulator
AXK18_RS07890	COG0758	DNA mediated transformation
AXK18_RS07900	COG0697	spore germination
AXK18_RS07905	COG1309	transcriptional regulator
AXK18_RS07920	COG0386	Belongs to the glutathione peroxidase family
AXK18_RS07985	COG1121	(ABC) transporter
AXK18_RS07990	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AXK18_RS07995	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS08000	COG2837	iron assimilation
AXK18_RS08010	COG0281	malic enzyme
AXK18_RS08055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXK18_RS08055	COG0519	Catalyzes the synthesis of GMP from XMP
AXK18_RS08060	COG4399	Belongs to the UPF0754 family
AXK18_RS08065	COG2259	Doxx family
AXK18_RS08070	COG0586	Pfam SNARE associated Golgi protein
AXK18_RS08085	COG1192	Involved in chromosome partitioning
AXK18_RS08095	COG0271	Belongs to the BolA IbaG family
AXK18_RS08115	COG2267	carboxylic ester hydrolase activity
AXK18_RS08130	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK18_RS08140	COG3321	synthase
AXK18_RS08140	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AXK18_RS08140	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AXK18_RS08140	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AXK18_RS08145	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS08155	COG2197	response regulator
AXK18_RS08165	COG3916	Acyl-homoserine-lactone synthase
AXK18_RS08170	COG0477	Major facilitator Superfamily
AXK18_RS08175	COG1024	Enoyl-CoA hydratase
AXK18_RS08180	COG1024	Enoyl-CoA hydratase
AXK18_RS08185	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS08190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXK18_RS08210	COG1113	amino acid transport
AXK18_RS08215	COG1113	amino acid transport
AXK18_RS08325	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AXK18_RS08340	COG1802	Transcriptional regulator
AXK18_RS08350	COG1448	Aminotransferase
AXK18_RS08355	COG0277	FAD linked oxidase domain protein
AXK18_RS08365	COG2186	Transcriptional regulator
AXK18_RS08375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AXK18_RS08400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AXK18_RS08415	COG0438	transferase activity, transferring glycosyl groups
AXK18_RS08425	COG0438	transferase activity, transferring glycosyl groups
AXK18_RS08430	COG1215	transferase activity, transferring glycosyl groups
AXK18_RS08470	COG0728	peptidoglycan biosynthetic process
AXK18_RS08475	COG3023	N-Acetylmuramoyl-L-alanine amidase
AXK18_RS08530	COG0546	phosphoglycolate phosphatase activity
AXK18_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS08560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK18_RS08565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK18_RS08570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK18_RS08575	COG1116	anion transmembrane transporter activity
AXK18_RS08580	COG1309	transcriptional regulator
AXK18_RS08585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AXK18_RS08595	COG0196	riboflavin kinase activity
AXK18_RS08600	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AXK18_RS08610	COG1047	Peptidyl-prolyl cis-trans
AXK18_RS08650	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AXK18_RS08655	COG0657	acetylesterase activity
AXK18_RS08705	COG2951	lytic endotransglycosylase activity
AXK18_RS08710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AXK18_RS08730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AXK18_RS08740	COG0671	phosphoesterase, PA-phosphatase related
AXK18_RS08745	COG0861	Integral membrane protein TerC family
AXK18_RS08755	COG0754	glutathionylspermidine amidase activity
AXK18_RS08765	COG0402	S-adenosylhomocysteine deaminase activity
AXK18_RS08785	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK18_RS08790	COG1230	cation diffusion facilitator family transporter
AXK18_RS08805	COG0706	membrane insertase activity
AXK18_RS08830	COG0592	DNA-directed DNA polymerase activity
AXK18_RS08840	COG0187	DNA topoisomerase II activity
AXK18_RS08850	COG0586	Pfam SNARE associated Golgi protein
AXK18_RS08855	COG0488	(ABC) transporter
AXK18_RS08885	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AXK18_RS08890	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AXK18_RS08935	COG0733	neurotransmitter:sodium symporter activity
AXK18_RS08975	COG2233	PERMEase
AXK18_RS08990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS09025	COG2814	Major facilitator Superfamily
AXK18_RS09030	COG0656	L-ascorbic acid biosynthetic process
AXK18_RS09035	COG0583	DNA-binding transcription factor activity
AXK18_RS09050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK18_RS09055	COG1064	alcohol dehydrogenase
AXK18_RS09060	COG2818	Glycosylase
AXK18_RS09075	COG1194	a g-specific adenine glycosylase
AXK18_RS09095	COG2983	Belongs to the UPF0260 family
AXK18_RS09100	COG2133	pyrroloquinoline quinone binding
AXK18_RS09105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AXK18_RS09110	COG2116	formate transmembrane transporter activity
AXK18_RS09130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AXK18_RS09135	COG1335	isochorismatase
AXK18_RS09140	COG0385	Bile acid
AXK18_RS09145	COG0534	Mate efflux family protein
AXK18_RS09150	COG1683	Conserved Protein
AXK18_RS09170	COG0625	glutathione transferase activity
AXK18_RS09180	COG1113	amino acid transport
AXK18_RS09190	COG0523	cobalamin synthesis protein
AXK18_RS09200	COG2188	Transcriptional regulator
AXK18_RS09230	COG0010	Belongs to the arginase family
AXK18_RS09245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AXK18_RS09250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AXK18_RS09260	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AXK18_RS09370	COG0534	Mate efflux family protein
AXK18_RS09375	COG0436	Aminotransferase
AXK18_RS09380	COG2733	membrane
AXK18_RS09395	COG2918	glutathione biosynthetic process
AXK18_RS09425	COG3150	esterase
AXK18_RS09435	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS09440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AXK18_RS09450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AXK18_RS09460	COG2233	PERMEase
AXK18_RS09465	COG2351	hydroxyisourate hydrolase activity
AXK18_RS09500	COG3706	GGDEF domain
AXK18_RS09515	COG1393	Belongs to the ArsC family
AXK18_RS09520	COG0708	Exodeoxyribonuclease III
AXK18_RS09540	COG0189	ligase activity
AXK18_RS09560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AXK18_RS09570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AXK18_RS09585	COG4942	peptidase
AXK18_RS09595	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK18_RS09605	COG2119	membrane
AXK18_RS09640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AXK18_RS09660	COG1902	pentaerythritol trinitrate reductase activity
AXK18_RS09665	COG1519	Transferase
AXK18_RS09670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXK18_RS09675	COG0668	transmembrane transport
AXK18_RS09685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXK18_RS09690	COG1335	isochorismatase
AXK18_RS09695	COG1522	sequence-specific DNA binding
AXK18_RS09700	COG3328	transposase activity
AXK18_RS09725	COG2205	protein histidine kinase activity
AXK18_RS09725	COG2198	Histidine kinase
AXK18_RS09725	COG0784	Response regulator, receiver
AXK18_RS09730	COG3162	membrane
AXK18_RS09735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXK18_RS09745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK18_RS09765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AXK18_RS09770	COG1309	transcriptional regulator
AXK18_RS09790	COG0352	thiamine-phosphate diphosphorylase activity
AXK18_RS09790	COG0351	phosphomethylpyrimidine kinase
AXK18_RS09790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AXK18_RS09800	COG2814	Major facilitator Superfamily
AXK18_RS09815	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AXK18_RS09825	COG1113	amino acid transport
AXK18_RS09835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXK18_RS09840	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS09850	COG1335	isochorismatase
AXK18_RS09880	COG2814	Major facilitator Superfamily
AXK18_RS09885	COG0583	DNA-binding transcription factor activity
AXK18_RS09905	COG0667	Aldo Keto reductase
AXK18_RS09940	COG1733	regulation of RNA biosynthetic process
AXK18_RS09950	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXK18_RS10015	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AXK18_RS10030	COG2329	Antibiotic biosynthesis monooxygenase
AXK18_RS10060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AXK18_RS10090	COG0427	acetyl-CoA hydrolase
AXK18_RS10115	COG0659	secondary active sulfate transmembrane transporter activity
AXK18_RS10120	COG4221	oxidoreductase activity
AXK18_RS10125	COG2873	o-acetylhomoserine
AXK18_RS10130	COG0488	(ABC) transporter
AXK18_RS10215	COG0833	amino acid
AXK18_RS10260	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AXK18_RS10265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AXK18_RS10280	COG2226	methyltransferase
AXK18_RS10330	COG0067	glutamate synthase
AXK18_RS10330	COG0070	glutamate synthase
AXK18_RS10330	COG0069	glutamate synthase activity
AXK18_RS10335	COG0493	'glutamate synthase
AXK18_RS10345	COG1704	LemA family
AXK18_RS10350	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AXK18_RS10370	COG3307	-O-antigen
AXK18_RS10390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AXK18_RS10405	COG0194	GDP metabolic process
AXK18_RS10455	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AXK18_RS10475	COG5380	lipid catabolic process
AXK18_RS10480	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AXK18_RS10505	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AXK18_RS10510	COG0277	FAD linked oxidase domain protein
AXK18_RS10520	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AXK18_RS10540	COG1289	transmembrane transporter activity
AXK18_RS10550	COG0628	permease
AXK18_RS10555	COG1192	Involved in chromosome partitioning
AXK18_RS10585	COG0833	amino acid
AXK18_RS10590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AXK18_RS10605	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS10690	COG0517	IMP dehydrogenase activity
AXK18_RS10695	COG1983	PspC domain protein
AXK18_RS10705	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS10720	COG0408	coproporphyrinogen oxidase activity
AXK18_RS10740	COG0513	Belongs to the DEAD box helicase family
AXK18_RS10750	COG1127	ABC transporter
AXK18_RS10755	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AXK18_RS10765	COG2854	intermembrane phospholipid transfer
AXK18_RS10775	COG0598	Magnesium transport protein CorA
AXK18_RS10785	COG0494	nUDIX hydrolase
AXK18_RS10790	COG1040	competence protein
AXK18_RS10795	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AXK18_RS10815	COG1946	Acyl-CoA thioesterase
AXK18_RS10820	COG1301	dicarboxylic acid transport
AXK18_RS10835	COG1959	2 iron, 2 sulfur cluster binding
AXK18_RS10840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK18_RS10840	COG1017	nitric oxide dioxygenase activity
AXK18_RS10845	COG0433	COG0433 Predicted ATPase
AXK18_RS10850	COG0626	cystathionine gamma-synthase activity
AXK18_RS11005	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS11010	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AXK18_RS11040	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AXK18_RS11045	COG0339	signal peptide processing
AXK18_RS11050	COG0557	exoribonuclease II activity
AXK18_RS11095	COG0179	Fumarylacetoacetate (FAA) hydrolase
AXK18_RS11100	COG2169	Transcriptional regulator
AXK18_RS11105	COG0697	spore germination
AXK18_RS11110	COG1295	ribonuclease BN
AXK18_RS11145	COG1702	phosphate starvation-inducible protein PhoH
AXK18_RS11155	COG1196	nuclear chromosome segregation
AXK18_RS11155	COG0741	lytic transglycosylase activity
AXK18_RS11155	COG0739	heme binding
AXK18_RS11185	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AXK18_RS11190	COG1183	phosphatidylcholine synthase activity
AXK18_RS11235	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS11240	COG1309	transcriptional regulator
AXK18_RS11260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AXK18_RS11265	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS11285	COG2969	positive regulation of protein catabolic process
AXK18_RS11295	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AXK18_RS11310	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AXK18_RS11315	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AXK18_RS11335	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AXK18_RS11350	COG1408	metallophosphoesterase
AXK18_RS11360	COG2199	diguanylate cyclase activity
AXK18_RS11430	COG1607	acyl-coa hydrolase
AXK18_RS11460	COG2350	Protein conserved in bacteria
AXK18_RS11470	COG0613	PHP domain protein
AXK18_RS11485	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AXK18_RS11490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AXK18_RS11500	COG1862	Preprotein translocase
AXK18_RS11530	COG2205	protein histidine kinase activity
AXK18_RS11535	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AXK18_RS11555	COG0726	polysaccharide deacetylase
AXK18_RS11565	COG0438	transferase activity, transferring glycosyl groups
AXK18_RS11630	COG0625	glutathione transferase activity
AXK18_RS11635	COG0583	DNA-binding transcription factor activity
AXK18_RS11640	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS11645	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS11655	COG2205	protein histidine kinase activity
AXK18_RS11660	COG0745	RESPONSE REGULATOR receiver
AXK18_RS11665	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AXK18_RS11685	COG2096	Adenosyltransferase
AXK18_RS11735	COG0285	dihydrofolate synthase activity
AXK18_RS11755	COG0450	alkyl hydroperoxide reductase
AXK18_RS11770	COG0477	Major facilitator Superfamily
AXK18_RS11775	COG1272	protein, Hemolysin III
AXK18_RS11805	COG0183	Belongs to the thiolase family
AXK18_RS11810	COG2207	Transcriptional regulator
AXK18_RS11830	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK18_RS11850	COG0183	Belongs to the thiolase family
AXK18_RS11860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AXK18_RS11860	COG2885	chlorophyll binding
AXK18_RS11870	COG1690	Belongs to the RtcB family
AXK18_RS11875	COG0833	amino acid
AXK18_RS11890	COG1217	gtp-binding protein TYPA
AXK18_RS11915	COG2094	Belongs to the DNA glycosylase MPG family
AXK18_RS11920	COG4772	TonB-dependent receptor
AXK18_RS11935	COG1902	pentaerythritol trinitrate reductase activity
AXK18_RS11940	COG0679	Auxin Efflux Carrier
AXK18_RS11950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK18_RS11955	COG0354	folic acid binding
AXK18_RS11965	COG3189	MarR family transcriptional regulator
AXK18_RS11970	COG2824	Alkylphosphonate utilization operon protein PhnA
AXK18_RS11975	COG3422	double-strand break repair
AXK18_RS12015	COG0840	transmembrane signaling receptor activity
AXK18_RS12035	COG5510	response to toxic substance
AXK18_RS12045	COG2832	Protein of unknown function (DUF454)
AXK18_RS12050	COG1376	ErfK ybiS ycfS ynhG family protein
AXK18_RS12110	COG1289	transmembrane transporter activity
AXK18_RS12115	COG2814	Major facilitator Superfamily
AXK18_RS12135	COG1115	amino acid carrier protein
AXK18_RS12140	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXK18_RS12145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXK18_RS12150	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AXK18_RS12190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXK18_RS12200	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AXK18_RS12205	COG1077	Cell shape determining protein MreB Mrl
AXK18_RS12210	COG1792	Involved in formation and maintenance of cell shape
AXK18_RS12215	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AXK18_RS12220	COG0424	maF-like protein
AXK18_RS12225	COG1530	ribonuclease E activity
AXK18_RS12235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK18_RS12245	COG0560	Phosphoserine phosphatase
AXK18_RS12255	COG2249	NAD(P)H dehydrogenase (quinone) activity
AXK18_RS12280	COG2207	Transcriptional regulator
AXK18_RS12305	COG2828	Protein conserved in bacteria
AXK18_RS12310	COG0142	geranyltranstransferase activity
AXK18_RS12315	COG2315	Protein conserved in bacteria
AXK18_RS12330	COG1752	Esterase of the alpha-beta hydrolase superfamily
AXK18_RS12355	COG0745	RESPONSE REGULATOR receiver
AXK18_RS12360	COG0642	Histidine kinase
AXK18_RS12370	COG0004	ammonium transporteR
AXK18_RS12380	COG0583	DNA-binding transcription factor activity
AXK18_RS12400	COG0525	valine-tRNA ligase activity
AXK18_RS12410	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS12420	COG0393	Putative heavy-metal-binding
AXK18_RS12425	COG0393	Putative heavy-metal-binding
AXK18_RS12430	COG1538	Outer membrane efflux protein
AXK18_RS12440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS12445	COG0671	phosphoesterase, PA-phosphatase related
AXK18_RS12475	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AXK18_RS12490	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AXK18_RS12490	COG1648	precorrin-2 dehydrogenase activity
AXK18_RS12495	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AXK18_RS12500	COG1733	regulation of RNA biosynthetic process
AXK18_RS12510	COG0531	amino acid
AXK18_RS12525	COG0321	lipoyl(octanoyl) transferase activity
AXK18_RS12530	COG2921	Belongs to the UPF0250 family
AXK18_RS12570	COG2009	succinate dehydrogenase
AXK18_RS12575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AXK18_RS12580	COG1053	succinate dehydrogenase
AXK18_RS12585	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AXK18_RS12610	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK18_RS12630	COG2354	Protein conserved in bacteria
AXK18_RS12635	COG2321	neutral zinc metallopeptidase
AXK18_RS12675	COG2843	Capsule synthesis protein
AXK18_RS12690	COG0589	response to stress
AXK18_RS12710	COG0505	Belongs to the CarA family
AXK18_RS12735	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXK18_RS12740	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AXK18_RS12790	COG0477	Major facilitator Superfamily
AXK18_RS12795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AXK18_RS12810	COG1597	lipid kinase activity
AXK18_RS12815	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AXK18_RS12845	COG0584	glycerophosphoryl diester phosphodiesterase
AXK18_RS12865	COG0741	lytic transglycosylase activity
AXK18_RS12890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AXK18_RS12905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK18_RS12935	COG0778	Nitroreductase
AXK18_RS12950	COG1929	Belongs to the glycerate kinase type-1 family
AXK18_RS12955	COG0243	molybdopterin cofactor binding
AXK18_RS12960	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AXK18_RS12965	COG3339	Conserved Protein
AXK18_RS12975	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AXK18_RS12990	COG1113	amino acid transport
AXK18_RS13000	COG0019	diaminopimelate decarboxylase activity
AXK18_RS13010	COG1280	lysine exporter protein (LysE YggA)
AXK18_RS13015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AXK18_RS13045	COG0463	Glycosyl transferase, family 2
AXK18_RS13065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS13095	COG4591	ABC-type transport system involved in lipoprotein release permease component
AXK18_RS13100	COG1136	(ABC) transporter
AXK18_RS13105	COG0658	competence protein
AXK18_RS13105	COG2333	competence protein COMEC
AXK18_RS13115	COG0616	signal peptide processing
AXK18_RS13115	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AXK18_RS13120	COG0596	Alpha beta hydrolase
AXK18_RS13125	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AXK18_RS13135	COG0628	permease
AXK18_RS13170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AXK18_RS13190	COG0823	Involved in the tonB-independent uptake of proteins
AXK18_RS13210	COG0824	Thioesterase
AXK18_RS13215	COG1473	amidohydrolase
AXK18_RS13240	COG2814	Major facilitator Superfamily
AXK18_RS13250	COG1024	Enoyl-CoA hydratase
AXK18_RS13255	COG1056	cytidyltransferase-related domain
AXK18_RS13255	COG1051	belongs to the nudix hydrolase family
AXK18_RS13265	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AXK18_RS13280	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AXK18_RS13295	COG4625	pathogenesis
AXK18_RS13300	COG0583	DNA-binding transcription factor activity
AXK18_RS13305	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AXK18_RS13310	COG4208	sulfate ABC transporter
AXK18_RS13315	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AXK18_RS13325	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AXK18_RS13330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AXK18_RS13335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AXK18_RS13355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK18_RS13385	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AXK18_RS13395	COG1381	Involved in DNA repair and RecF pathway recombination
AXK18_RS13400	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AXK18_RS13410	COG4221	oxidoreductase activity
AXK18_RS13440	COG0436	Aminotransferase
AXK18_RS13460	COG0556	nucleotide-excision repair
AXK18_RS13515	COG2070	2-Nitropropane dioxygenase
AXK18_RS13545	COG1215	transferase activity, transferring glycosyl groups
AXK18_RS13560	COG0415	Belongs to the DNA photolyase family
AXK18_RS13570	COG1252	NADH dehydrogenase
AXK18_RS13575	COG1686	Belongs to the peptidase S11 family
AXK18_RS13590	COG1187	pseudouridine synthase activity
AXK18_RS13615	COG0477	Major facilitator Superfamily
AXK18_RS13620	COG0583	DNA-binding transcription factor activity
AXK18_RS13625	COG1823	symporter activity
AXK18_RS13635	COG0612	Peptidase, M16
AXK18_RS13660	COG0352	thiamine-phosphate diphosphorylase activity
AXK18_RS13695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK18_RS13720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AXK18_RS13725	COG0076	glutamate decarboxylase activity
AXK18_RS13735	COG1522	sequence-specific DNA binding
AXK18_RS13740	COG3961	Belongs to the TPP enzyme family
AXK18_RS13745	COG1113	amino acid transport
AXK18_RS13750	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AXK18_RS13755	COG0573	inorganic phosphate transmembrane transporter activity
AXK18_RS13765	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AXK18_RS13770	COG0616	signal peptide processing
AXK18_RS13780	COG3328	transposase activity
AXK18_RS13810	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AXK18_RS13815	COG1686	Belongs to the peptidase S11 family
AXK18_RS13840	COG0583	DNA-binding transcription factor activity
AXK18_RS13845	COG1067	ATP-dependent peptidase activity
AXK18_RS13895	COG2879	small protein
AXK18_RS13930	COG2508	Transcriptional regulator
AXK18_RS13930	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AXK18_RS13950	COG1113	amino acid transport
AXK18_RS13955	COG0583	DNA-binding transcription factor activity
AXK18_RS13960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK18_RS13965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AXK18_RS13975	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS13980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK18_RS13985	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AXK18_RS13985	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXK18_RS14020	COG2814	Major facilitator Superfamily
AXK18_RS14025	COG4948	Mandelate Racemase Muconate Lactonizing
AXK18_RS14035	COG1309	transcriptional regulator
AXK18_RS14055	COG1741	Belongs to the pirin family
AXK18_RS14065	COG2964	Protein conserved in bacteria
AXK18_RS14080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AXK18_RS14085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK18_RS14090	COG4605	iron ion homeostasis
AXK18_RS14095	COG4604	ABC transporter, ATP-binding protein
AXK18_RS14100	COG4607	ABC-type enterochelin transport system periplasmic component
AXK18_RS14105	COG4774	siderophore transport
AXK18_RS14120	COG1021	2,3-dihydroxybenzoate-AMP ligase
AXK18_RS14125	COG1535	isochorismatase
AXK18_RS14125	COG3433	isochorismatase activity
AXK18_RS14140	COG1132	(ABC) transporter
AXK18_RS14145	COG1132	(ABC) transporter
AXK18_RS14150	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AXK18_RS14160	COG1169	isochorismate synthase
AXK18_RS14175	COG3739	integral membrane protein
AXK18_RS14200	COG0302	gtp cyclohydrolase
AXK18_RS14210	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AXK18_RS14245	COG0512	Glutamine amidotransferase of anthranilate synthase
AXK18_RS14260	COG0174	glutamine synthetase
AXK18_RS14270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AXK18_RS14305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AXK18_RS14310	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AXK18_RS14315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AXK18_RS14335	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AXK18_RS14340	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AXK18_RS14345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AXK18_RS14360	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS14365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXK18_RS14370	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK18_RS14380	COG2223	nitrite transmembrane transporter activity
AXK18_RS14390	COG0024	Methionine aminopeptidase
AXK18_RS14395	COG0052	Belongs to the universal ribosomal protein uS2 family
AXK18_RS14410	COG2207	Transcriptional regulator
AXK18_RS14435	COG2951	lytic endotransglycosylase activity
AXK18_RS14440	COG0772	Belongs to the SEDS family
AXK18_RS14455	COG0842	Transport permease protein
AXK18_RS14460	COG1131	(ABC) transporter
AXK18_RS14505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS14520	COG4215	(ABC) transporter
AXK18_RS14525	COG4160	amino acid transport
AXK18_RS14530	COG4598	ABC transporter
AXK18_RS14540	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AXK18_RS14545	COG0826	peptidase U32
AXK18_RS14550	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK18_RS14565	COG1720	tRNA m6t6A37 methyltransferase activity
AXK18_RS14575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AXK18_RS14590	COG0642	Histidine kinase
AXK18_RS14610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AXK18_RS14615	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AXK18_RS14620	COG3139	Protein of unknown function (DUF1315)
AXK18_RS14625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AXK18_RS14635	COG1301	dicarboxylic acid transport
AXK18_RS14640	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS14645	COG2819	hydrolase of the alpha beta superfamily
AXK18_RS14655	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AXK18_RS14665	COG2195	Cleaves the N-terminal amino acid of tripeptides
AXK18_RS14670	COG1234	tRNA 3'-trailer cleavage
AXK18_RS14720	COG0513	Belongs to the DEAD box helicase family
AXK18_RS14730	COG0778	Nitroreductase
AXK18_RS14760	COG1286	toxin biosynthetic process
AXK18_RS14785	COG4783	chaperone-mediated protein folding
AXK18_RS14790	COG1610	YqeY-like protein
AXK18_RS14890	COG3111	PFAM Bacterial OB fold (BOF) protein
AXK18_RS14915	COG3243	poly(R)-hydroxyalkanoic acid synthase
AXK18_RS14920	COG0786	glutamate:sodium symporter activity
AXK18_RS14930	COG2186	Transcriptional regulator
AXK18_RS15005	COG1301	dicarboxylic acid transport
AXK18_RS15015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXK18_RS15020	COG2011	ABC-type metal ion transport system permease component
AXK18_RS15025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AXK18_RS15030	COG1464	Belongs to the NlpA lipoprotein family
AXK18_RS15035	COG0151	Belongs to the GarS family
AXK18_RS15040	COG0138	bifunctional purine biosynthesis protein purh
AXK18_RS15045	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AXK18_RS15075	COG2308	Evidence 4 Homologs of previously reported genes of
AXK18_RS15085	COG1305	Transglutaminase-like
AXK18_RS15095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AXK18_RS15100	COG0305	Participates in initiation and elongation during chromosome replication
AXK18_RS15125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AXK18_RS15135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AXK18_RS15140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AXK18_RS15175	COG3658	cytochrome
AXK18_RS15185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AXK18_RS15225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK18_RS15230	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK18_RS15245	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS15250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AXK18_RS15255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK18_RS15280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AXK18_RS15285	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AXK18_RS15295	COG2205	protein histidine kinase activity
AXK18_RS15300	COG0745	RESPONSE REGULATOR receiver
AXK18_RS15305	COG0174	glutamine synthetase
AXK18_RS15325	COG0729	surface antigen
AXK18_RS15360	COG2814	Major facilitator Superfamily
AXK18_RS15390	COG1187	pseudouridine synthase activity
AXK18_RS15410	COG0802	atpase or kinase
AXK18_RS15415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AXK18_RS15425	COG1923	regulation of RNA biosynthetic process
AXK18_RS15430	COG0697	spore germination
AXK18_RS15445	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXK18_RS15455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AXK18_RS15460	COG0519	Catalyzes the synthesis of GMP from XMP
AXK18_RS15460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AXK18_RS15465	COG4302	ethanolamine ammonia-lyase activity
AXK18_RS15470	COG4303	Ethanolamine ammonia lyase large subunit
AXK18_RS15475	COG0531	amino acid
AXK18_RS15495	COG1454	alcohol dehydrogenase
AXK18_RS15500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AXK18_RS15510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AXK18_RS15530	COG0308	aminopeptidase N
AXK18_RS15560	COG1605	Chorismate mutase
AXK18_RS15580	COG1309	transcriptional regulator
AXK18_RS15590	COG0668	transmembrane transport
AXK18_RS15645	COG0488	(ABC) transporter
AXK18_RS15650	COG0589	response to stress
AXK18_RS15665	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AXK18_RS15675	COG3135	benzoate transporter
AXK18_RS15680	COG1522	sequence-specific DNA binding
AXK18_RS15690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AXK18_RS15715	COG2030	dehydratase
AXK18_RS15720	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AXK18_RS15735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AXK18_RS15745	COG0824	Thioesterase
AXK18_RS15750	COG1454	alcohol dehydrogenase
AXK18_RS15760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AXK18_RS15780	COG0069	glutamate synthase activity
AXK18_RS15800	COG2814	Major facilitator Superfamily
AXK18_RS15815	COG0511	ligase activity, forming carbon-carbon bonds
AXK18_RS15835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AXK18_RS15835	COG1116	anion transmembrane transporter activity
AXK18_RS15840	COG0745	RESPONSE REGULATOR receiver
AXK18_RS15850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK18_RS15850	COG2146	nitrite reductase [NAD(P)H] activity
AXK18_RS15855	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AXK18_RS15860	COG0243	molybdopterin cofactor binding
AXK18_RS15870	COG0243	molybdopterin cofactor binding
AXK18_RS15875	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AXK18_RS15890	COG0521	Mo-molybdopterin cofactor biosynthetic process
AXK18_RS15890	COG0315	cyclic pyranopterin monophosphate synthase activity
AXK18_RS15895	COG0303	'Molybdopterin
AXK18_RS15905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AXK18_RS15930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AXK18_RS15935	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AXK18_RS15995	COG2204	response regulator
AXK18_RS16000	COG3852	Histidine kinase
AXK18_RS16025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AXK18_RS16030	COG0575	Belongs to the CDS family
AXK18_RS16065	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXK18_RS16080	COG2137	regulation of response to DNA damage stimulus
AXK18_RS16090	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AXK18_RS16095	COG1011	Hydrolase
AXK18_RS16145	COG0659	secondary active sulfate transmembrane transporter activity
AXK18_RS16150	COG2135	peptidase activity
AXK18_RS16165	COG5001	Diguanylate cyclase
AXK18_RS16165	COG3300	MHYT domain
AXK18_RS16185	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK18_RS16185	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AXK18_RS16185	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AXK18_RS16190	COG1105	Belongs to the carbohydrate kinase PfkB family
AXK18_RS16195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AXK18_RS16195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AXK18_RS16225	COG0024	Methionine aminopeptidase
AXK18_RS16230	COG0583	DNA-binding transcription factor activity
AXK18_RS16240	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AXK18_RS16245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AXK18_RS16250	COG0516	GMP reductase activity
AXK18_RS16250	COG0517	IMP dehydrogenase activity
AXK18_RS16275	COG0552	protein localization to endoplasmic reticulum
AXK18_RS16285	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AXK18_RS16300	COG4890	Cyd operon protein YbgT
AXK18_RS16305	COG1294	oxidase, subunit
AXK18_RS16340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AXK18_RS16345	COG4774	siderophore transport
AXK18_RS16360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AXK18_RS16365	COG0569	domain protein
AXK18_RS16370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AXK18_RS16400	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AXK18_RS16405	COG0542	response to heat
AXK18_RS16430	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK18_RS16430	COG1902	pentaerythritol trinitrate reductase activity
AXK18_RS16480	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AXK18_RS16490	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXK18_RS16495	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK18_RS16505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AXK18_RS16510	COG0596	Alpha beta hydrolase
AXK18_RS16515	COG2271	Major facilitator Superfamily
AXK18_RS16520	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AXK18_RS16525	COG3485	protocatechuate 3,4-dioxygenase
AXK18_RS16530	COG3485	protocatechuate 3,4-dioxygenase
AXK18_RS16535	COG0710	3-dehydroquinate dehydratase activity
AXK18_RS16540	COG3420	alginic acid biosynthetic process
AXK18_RS16545	COG3659	wide pore channel activity
AXK18_RS16550	COG4993	Dehydrogenase
AXK18_RS16560	COG2391	methyltransferase activity
AXK18_RS16575	COG1414	Transcriptional regulator
AXK18_RS16580	COG0583	DNA-binding transcription factor activity
AXK18_RS16585	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS16610	COG2814	Major facilitator Superfamily
AXK18_RS16620	COG0154	amidase activity
AXK18_RS16640	COG4638	Rieske (2fe-2S)
AXK18_RS16650	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS16660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AXK18_RS16670	COG3733	amine oxidase
AXK18_RS16680	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS16690	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AXK18_RS16695	COG0183	Belongs to the thiolase family
AXK18_RS16700	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK18_RS16705	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AXK18_RS16715	COG4829	muconolactone delta-isomerase
AXK18_RS16720	COG4948	Mandelate Racemase Muconate Lactonizing
AXK18_RS16725	COG0583	DNA-binding transcription factor activity
AXK18_RS16735	COG2186	Transcriptional regulator
AXK18_RS16755	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS16775	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS16780	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS16785	COG3829	transcription factor binding
AXK18_RS16795	COG3162	membrane
AXK18_RS16810	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS16825	COG0753	catalase activity
AXK18_RS16850	COG1846	Transcriptional regulator
AXK18_RS16855	COG0446	pyridine nucleotide-disulphide oxidoreductase
AXK18_RS16855	COG1902	pentaerythritol trinitrate reductase activity
AXK18_RS16865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AXK18_RS16895	COG1309	transcriptional regulator
AXK18_RS16905	COG1335	isochorismatase
AXK18_RS16910	COG0583	DNA-binding transcription factor activity
AXK18_RS16920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AXK18_RS16920	COG0475	glutathione-regulated potassium exporter activity
AXK18_RS16930	COG1473	amidohydrolase
AXK18_RS16945	COG2831	hemolysin activation secretion protein
AXK18_RS16980	COG2188	Transcriptional regulator
AXK18_RS16995	COG0583	DNA-binding transcription factor activity
AXK18_RS17025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXK18_RS17045	COG1566	PFAM secretion protein HlyD family protein
AXK18_RS17060	COG1012	belongs to the aldehyde dehydrogenase family
AXK18_RS17065	COG0129	dihydroxy-acid dehydratase activity
AXK18_RS17075	COG0583	DNA-binding transcription factor activity
AXK18_RS17080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AXK18_RS17090	COG2084	Dehydrogenase
AXK18_RS17095	COG2207	Transcriptional regulator
AXK18_RS17110	COG1064	alcohol dehydrogenase
AXK18_RS17120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AXK18_RS17125	COG1120	ATPase activity
AXK18_RS17145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AXK18_RS17265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AXK18_RS17320	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS17335	COG2207	Transcriptional regulator
AXK18_RS17345	COG2205	protein histidine kinase activity
AXK18_RS17350	COG0745	RESPONSE REGULATOR receiver
AXK18_RS17355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AXK18_RS17360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK18_RS17365	COG1538	Outer membrane efflux protein
AXK18_RS17375	COG2072	flavoprotein involved in K transport
AXK18_RS17395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AXK18_RS17415	COG3539	Fimbrial protein
AXK18_RS17445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AXK18_RS17455	COG0753	catalase activity
AXK18_RS17470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AXK18_RS17535	COG3433	isochorismatase activity
AXK18_RS17535	COG1535	isochorismatase
AXK18_RS17540	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS17545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AXK18_RS17550	COG4149	molybdate abc transporter
AXK18_RS17555	COG0725	ABC transporter, periplasmic molybdate-binding protein
AXK18_RS17565	COG4638	Rieske (2fe-2S)
AXK18_RS17570	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AXK18_RS17575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AXK18_RS17575	COG0543	2 iron, 2 sulfur cluster binding
AXK18_RS17600	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS17615	COG2207	Transcriptional regulator
AXK18_RS17625	COG1028	Short-chain dehydrogenase reductase Sdr
AXK18_RS17630	COG2610	gluconate transmembrane transporter activity
AXK18_RS17640	COG0583	DNA-binding transcription factor activity
AXK18_RS17650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AXK18_RS17655	COG2031	fatty acid transporter
AXK18_RS17660	COG0183	Belongs to the thiolase family
AXK18_RS17665	COG0583	DNA-binding transcription factor activity
AXK18_RS17670	COG0583	DNA-binding transcription factor activity
AXK18_RS17715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AXK18_RS17720	COG4521	taurine ABC transporter
AXK18_RS17735	COG2188	Transcriptional regulator
AXK18_RS17745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AXK18_RS17750	COG1733	regulation of RNA biosynthetic process
AXK18_RS17755	COG2207	Transcriptional regulator
AXK18_RS17755	COG3708	Transcriptional regulator
AXK18_RS17770	COG0730	response to heat
AXK18_RS17780	COG3453	Protein conserved in bacteria
AXK18_RS17780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AXK18_RS17795	COG1063	alcohol dehydrogenase
AXK18_RS17805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AXK18_RS17810	COG0508	dehydrogenase complex catalyzes the overall conversion of
AXK18_RS17815	COG0022	dehydrogenase e1 component
AXK18_RS17820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AXK18_RS17825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AXK18_RS17840	COG3706	GGDEF domain
AXK18_RS17855	COG0133	tryptophan synthase activity
AXK18_RS17865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AXK18_RS17900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AXK18_RS17925	COG2226	methyltransferase
AXK18_RS17980	COG0842	Transport permease protein
AXK18_RS17985	COG0842	Transport permease protein
AXK18_RS17990	COG1131	(ABC) transporter
AXK18_RS18005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AXK18_RS18010	COG4773	Receptor
AXK18_RS18030	COG0730	response to heat
AXK18_RS18035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AXK18_RS18055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AXK18_RS18115	COG4264	IucA IucC family
AXK18_RS18120	COG4264	IucA IucC family
AXK18_RS18140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AXK18_RS18155	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS18160	COG1960	acyl-CoA dehydrogenase activity
AXK18_RS18165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AXK18_RS18170	COG2207	Transcriptional regulator
AXK18_RS18175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXK18_RS18180	COG0776	regulation of translation
AXK18_RS18205	COG0822	iron-sulfur transferase activity
AXK18_RS18210	COG0316	Belongs to the HesB IscA family
AXK18_RS18240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AXK18_RS18260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AXK18_RS18265	COG0702	epimerase
AXK18_RS18300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AXK18_RS18310	COG0339	signal peptide processing
AXK18_RS18370	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AXK18_RS18375	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AXK18_RS18405	COG0776	regulation of translation
AXK18_RS18470	COG0084	hydrolase, TatD family'
AXK18_RS18490	COG1663	tetraacyldisaccharide 4'-kinase activity
AXK18_RS18495	COG1132	(ABC) transporter
AXK18_RS18505	COG0811	peptide transport
AXK18_RS18510	COG1475	DNA binding
AXK18_RS18515	COG1192	Involved in chromosome partitioning
AXK18_RS18525	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AXK18_RS18540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AXK18_RS18545	COG0191	fructose-bisphosphate aldolase activity
AXK18_RS18565	COG0424	maF-like protein
AXK18_RS18570	COG2850	peptidyl-arginine hydroxylation
AXK18_RS18580	COG0640	Transcriptional regulator
AXK18_RS18590	COG3619	membrane
AXK18_RS18595	COG3122	Protein conserved in bacteria
AXK18_RS18600	COG1132	(ABC) transporter
AXK18_RS18620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AXK18_RS18625	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AXK18_RS18635	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXK18_RS18635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AXK18_RS18635	COG0506	proline dehydrogenase activity
AXK18_RS18740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AXK18_RS18825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AXK18_RS18860	COG0741	lytic transglycosylase activity
AXK18_RS18890	COG2826	transposase and inactivated derivatives, IS30 family
AXK18_RS18900	COG2826	transposase and inactivated derivatives, IS30 family
AXK18_RS18970	COG0484	heat shock protein binding
AXK18_RS19065	COG3853	Toxic anion resistance protein (TelA)
AXK18_RS19085	COG1475	DNA binding
AXK18_RS19150	COG1525	nuclease