locus-tag	class	description
JWB57_RS00040	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS00045	COG1309	transcriptional regulator
JWB57_RS00060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JWB57_RS00065	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS00085	COG2969	positive regulation of protein catabolic process
JWB57_RS00095	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JWB57_RS00110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JWB57_RS00115	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
JWB57_RS00135	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JWB57_RS00145	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWB57_RS00150	COG1408	metallophosphoesterase
JWB57_RS00160	COG2199	diguanylate cyclase activity
JWB57_RS00220	COG1607	acyl-coa hydrolase
JWB57_RS00250	COG2350	Protein conserved in bacteria
JWB57_RS00260	COG0613	PHP domain protein
JWB57_RS00265	COG3781	membrane
JWB57_RS00275	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JWB57_RS00290	COG1862	Preprotein translocase
JWB57_RS00335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWB57_RS00340	COG0629	single-stranded DNA binding
JWB57_RS00385	COG3646	Phage regulatory protein
JWB57_RS00395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JWB57_RS00540	COG4695	Portal protein
JWB57_RS00545	COG2205	protein histidine kinase activity
JWB57_RS00550	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
JWB57_RS00570	COG0726	polysaccharide deacetylase
JWB57_RS00575	COG0463	Glycosyl transferase, family 2
JWB57_RS00580	COG0438	transferase activity, transferring glycosyl groups
JWB57_RS00645	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS00650	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS00660	COG2205	protein histidine kinase activity
JWB57_RS00665	COG0745	RESPONSE REGULATOR receiver
JWB57_RS00670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
JWB57_RS00690	COG2096	Adenosyltransferase
JWB57_RS00740	COG0285	dihydrofolate synthase activity
JWB57_RS00760	COG0450	alkyl hydroperoxide reductase
JWB57_RS00775	COG0477	Major facilitator Superfamily
JWB57_RS00780	COG1272	protein, Hemolysin III
JWB57_RS00790	COG2153	protein acetylation
JWB57_RS00810	COG0183	Belongs to the thiolase family
JWB57_RS00815	COG2207	Transcriptional regulator
JWB57_RS00835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWB57_RS00855	COG0183	Belongs to the thiolase family
JWB57_RS00865	COG2885	chlorophyll binding
JWB57_RS00865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
JWB57_RS00875	COG1690	Belongs to the RtcB family
JWB57_RS00880	COG0833	amino acid
JWB57_RS00890	COG2233	PERMEase
JWB57_RS00895	COG1217	gtp-binding protein TYPA
JWB57_RS00920	COG2094	Belongs to the DNA glycosylase MPG family
JWB57_RS00925	COG4772	TonB-dependent receptor
JWB57_RS00930	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS00945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JWB57_RS00950	COG0354	folic acid binding
JWB57_RS00960	COG3189	MarR family transcriptional regulator
JWB57_RS00965	COG2824	Alkylphosphonate utilization operon protein PhnA
JWB57_RS00975	COG3422	double-strand break repair
JWB57_RS01015	COG0840	transmembrane signaling receptor activity
JWB57_RS01030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JWB57_RS01045	COG5510	response to toxic substance
JWB57_RS01055	COG2832	Protein of unknown function (DUF454)
JWB57_RS01060	COG1376	ErfK ybiS ycfS ynhG family protein
JWB57_RS01100	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
JWB57_RS01110	COG1289	transmembrane transporter activity
JWB57_RS01115	COG2814	Major facilitator Superfamily
JWB57_RS01140	COG1752	Esterase of the alpha-beta hydrolase superfamily
JWB57_RS01145	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JWB57_RS01150	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
JWB57_RS01175	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JWB57_RS01185	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JWB57_RS01190	COG1077	Cell shape determining protein MreB Mrl
JWB57_RS01195	COG1792	Involved in formation and maintenance of cell shape
JWB57_RS01200	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
JWB57_RS01205	COG0424	maF-like protein
JWB57_RS01210	COG1530	ribonuclease E activity
JWB57_RS01220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWB57_RS01230	COG0560	Phosphoserine phosphatase
JWB57_RS01240	COG2249	NAD(P)H dehydrogenase (quinone) activity
JWB57_RS01265	COG2207	Transcriptional regulator
JWB57_RS01675	COG0582	viral genome integration into host DNA
JWB57_RS01685	COG1113	amino acid transport
JWB57_RS01690	COG2828	Protein conserved in bacteria
JWB57_RS01695	COG0142	geranyltranstransferase activity
JWB57_RS01700	COG2315	Protein conserved in bacteria
JWB57_RS01715	COG1752	Esterase of the alpha-beta hydrolase superfamily
JWB57_RS01735	COG2194	sulfuric ester hydrolase activity
JWB57_RS01740	COG0745	RESPONSE REGULATOR receiver
JWB57_RS01745	COG0642	Histidine kinase
JWB57_RS01755	COG0004	ammonium transporteR
JWB57_RS01760	COG0583	DNA-binding transcription factor activity
JWB57_RS01780	COG0525	valine-tRNA ligase activity
JWB57_RS01790	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS01800	COG0393	Putative heavy-metal-binding
JWB57_RS01805	COG0393	Putative heavy-metal-binding
JWB57_RS01810	COG1538	Outer membrane efflux protein
JWB57_RS01820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS01825	COG0671	phosphoesterase, PA-phosphatase related
JWB57_RS01855	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
JWB57_RS01870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JWB57_RS01870	COG1648	precorrin-2 dehydrogenase activity
JWB57_RS01875	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JWB57_RS01880	COG1733	regulation of RNA biosynthetic process
JWB57_RS01890	COG0531	amino acid
JWB57_RS01905	COG0321	lipoyl(octanoyl) transferase activity
JWB57_RS01910	COG2921	Belongs to the UPF0250 family
JWB57_RS01945	COG2009	succinate dehydrogenase
JWB57_RS01950	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
JWB57_RS01955	COG1053	succinate dehydrogenase
JWB57_RS01960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JWB57_RS01985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWB57_RS02015	COG2354	Protein conserved in bacteria
JWB57_RS02020	COG2321	neutral zinc metallopeptidase
JWB57_RS02040	COG2843	Capsule synthesis protein
JWB57_RS02055	COG0589	response to stress
JWB57_RS02075	COG0505	Belongs to the CarA family
JWB57_RS02100	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JWB57_RS02105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
JWB57_RS02155	COG0477	Major facilitator Superfamily
JWB57_RS02160	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
JWB57_RS02175	COG1597	lipid kinase activity
JWB57_RS02180	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JWB57_RS02205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWB57_RS02210	COG0584	glycerophosphoryl diester phosphodiesterase
JWB57_RS02230	COG0741	lytic transglycosylase activity
JWB57_RS02250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JWB57_RS02265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWB57_RS02295	COG0778	Nitroreductase
JWB57_RS02310	COG1929	Belongs to the glycerate kinase type-1 family
JWB57_RS02315	COG0243	molybdopterin cofactor binding
JWB57_RS02320	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JWB57_RS02325	COG3339	Conserved Protein
JWB57_RS02335	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
JWB57_RS02350	COG1113	amino acid transport
JWB57_RS02360	COG0019	diaminopimelate decarboxylase activity
JWB57_RS02370	COG2267	carboxylic ester hydrolase activity
JWB57_RS02375	COG1280	lysine exporter protein (LysE YggA)
JWB57_RS02380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JWB57_RS02410	COG0463	Glycosyl transferase, family 2
JWB57_RS02430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS02465	COG4591	ABC-type transport system involved in lipoprotein release permease component
JWB57_RS02470	COG1136	(ABC) transporter
JWB57_RS02475	COG0658	competence protein
JWB57_RS02475	COG2333	competence protein COMEC
JWB57_RS02485	COG0616	signal peptide processing
JWB57_RS02485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
JWB57_RS02490	COG0596	Alpha beta hydrolase
JWB57_RS02495	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JWB57_RS02505	COG0628	permease
JWB57_RS02540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JWB57_RS02560	COG0823	Involved in the tonB-independent uptake of proteins
JWB57_RS02580	COG0824	Thioesterase
JWB57_RS02585	COG1473	amidohydrolase
JWB57_RS02605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JWB57_RS02605	COG0047	phosphoribosylformylglycinamidine synthase activity
JWB57_RS02610	COG2814	Major facilitator Superfamily
JWB57_RS02620	COG1024	Enoyl-CoA hydratase
JWB57_RS02625	COG1051	belongs to the nudix hydrolase family
JWB57_RS02625	COG1056	cytidyltransferase-related domain
JWB57_RS02635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JWB57_RS02650	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
JWB57_RS02665	COG4625	pathogenesis
JWB57_RS02670	COG0583	DNA-binding transcription factor activity
JWB57_RS02675	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
JWB57_RS02680	COG4208	sulfate ABC transporter
JWB57_RS02685	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
JWB57_RS02695	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
JWB57_RS02700	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
JWB57_RS02705	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
JWB57_RS02725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWB57_RS02740	COG0681	Belongs to the peptidase S26 family
JWB57_RS02755	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JWB57_RS02765	COG1381	Involved in DNA repair and RecF pathway recombination
JWB57_RS02770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
JWB57_RS02780	COG4221	oxidoreductase activity
JWB57_RS02810	COG0436	Aminotransferase
JWB57_RS02830	COG0556	nucleotide-excision repair
JWB57_RS02885	COG2070	2-Nitropropane dioxygenase
JWB57_RS02915	COG1215	transferase activity, transferring glycosyl groups
JWB57_RS02930	COG0415	Belongs to the DNA photolyase family
JWB57_RS02940	COG1252	NADH dehydrogenase
JWB57_RS02945	COG1686	Belongs to the peptidase S11 family
JWB57_RS02960	COG1187	pseudouridine synthase activity
JWB57_RS02980	COG0477	Major facilitator Superfamily
JWB57_RS02985	COG0583	DNA-binding transcription factor activity
JWB57_RS02990	COG1823	symporter activity
JWB57_RS03000	COG0612	Peptidase, M16
JWB57_RS03030	COG1203	CRISPR-associated helicase, Cas3
JWB57_RS03055	COG0352	thiamine-phosphate diphosphorylase activity
JWB57_RS03090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWB57_RS03105	COG1309	transcriptional regulator
JWB57_RS03115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JWB57_RS03120	COG0076	glutamate decarboxylase activity
JWB57_RS03130	COG1522	sequence-specific DNA binding
JWB57_RS03135	COG3961	Belongs to the TPP enzyme family
JWB57_RS03140	COG1113	amino acid transport
JWB57_RS03145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JWB57_RS03150	COG0573	inorganic phosphate transmembrane transporter activity
JWB57_RS03160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JWB57_RS03165	COG0616	signal peptide processing
JWB57_RS03200	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
JWB57_RS03205	COG1686	Belongs to the peptidase S11 family
JWB57_RS03230	COG0583	DNA-binding transcription factor activity
JWB57_RS03235	COG1067	ATP-dependent peptidase activity
JWB57_RS03260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
JWB57_RS03280	COG1966	Carbon starvation protein
JWB57_RS03285	COG2879	small protein
JWB57_RS03295	COG0583	DNA-binding transcription factor activity
JWB57_RS03300	COG0006	proline dipeptidase activity
JWB57_RS03305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWB57_RS03310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWB57_RS03320	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS03330	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWB57_RS03335	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWB57_RS03335	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JWB57_RS03395	COG1741	Belongs to the pirin family
JWB57_RS03405	COG2964	Protein conserved in bacteria
JWB57_RS03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWB57_RS03425	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JWB57_RS03430	COG4605	iron ion homeostasis
JWB57_RS03435	COG4604	ABC transporter, ATP-binding protein
JWB57_RS03440	COG4607	ABC-type enterochelin transport system periplasmic component
JWB57_RS03445	COG4774	siderophore transport
JWB57_RS03455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
JWB57_RS03460	COG1021	2,3-dihydroxybenzoate-AMP ligase
JWB57_RS03465	COG1535	isochorismatase
JWB57_RS03465	COG3433	isochorismatase activity
JWB57_RS03480	COG1132	(ABC) transporter
JWB57_RS03485	COG1132	(ABC) transporter
JWB57_RS03490	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
JWB57_RS03500	COG1169	isochorismate synthase
JWB57_RS03515	COG3739	integral membrane protein
JWB57_RS03535	COG0302	gtp cyclohydrolase
JWB57_RS03545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
JWB57_RS03580	COG0512	Glutamine amidotransferase of anthranilate synthase
JWB57_RS03595	COG0174	glutamine synthetase
JWB57_RS03605	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
JWB57_RS03640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JWB57_RS03645	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JWB57_RS03650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JWB57_RS03670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JWB57_RS03675	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JWB57_RS03680	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
JWB57_RS03695	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS03700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JWB57_RS03705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWB57_RS03715	COG2223	nitrite transmembrane transporter activity
JWB57_RS03725	COG0024	Methionine aminopeptidase
JWB57_RS03730	COG0052	Belongs to the universal ribosomal protein uS2 family
JWB57_RS03745	COG2207	Transcriptional regulator
JWB57_RS03770	COG2951	lytic endotransglycosylase activity
JWB57_RS03775	COG0772	Belongs to the SEDS family
JWB57_RS03790	COG0842	Transport permease protein
JWB57_RS03795	COG1131	(ABC) transporter
JWB57_RS03800	COG0582	viral genome integration into host DNA
JWB57_RS03840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWB57_RS03905	COG0305	Participates in initiation and elongation during chromosome replication
JWB57_RS04000	COG5410	chromosome segregation
JWB57_RS04120	COG0739	heme binding
JWB57_RS04235	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS04250	COG4215	(ABC) transporter
JWB57_RS04255	COG4160	amino acid transport
JWB57_RS04270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JWB57_RS04275	COG0826	peptidase U32
JWB57_RS04280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWB57_RS04295	COG1720	tRNA m6t6A37 methyltransferase activity
JWB57_RS04305	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JWB57_RS04320	COG0642	Histidine kinase
JWB57_RS04330	COG0494	nUDIX hydrolase
JWB57_RS04340	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
JWB57_RS04345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
JWB57_RS04350	COG3139	Protein of unknown function (DUF1315)
JWB57_RS04355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
JWB57_RS04360	COG1301	dicarboxylic acid transport
JWB57_RS04365	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS04370	COG2819	hydrolase of the alpha beta superfamily
JWB57_RS04380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JWB57_RS04390	COG2195	Cleaves the N-terminal amino acid of tripeptides
JWB57_RS04395	COG1234	tRNA 3'-trailer cleavage
JWB57_RS04420	COG2363	Small membrane protein
JWB57_RS04445	COG0513	Belongs to the DEAD box helicase family
JWB57_RS04455	COG0778	Nitroreductase
JWB57_RS04475	COG3328	transposase activity
JWB57_RS04550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
JWB57_RS04765	COG1286	toxin biosynthetic process
JWB57_RS04790	COG4783	chaperone-mediated protein folding
JWB57_RS04795	COG1610	YqeY-like protein
JWB57_RS04895	COG3111	PFAM Bacterial OB fold (BOF) protein
JWB57_RS04920	COG3243	poly(R)-hydroxyalkanoic acid synthase
JWB57_RS04925	COG0786	glutamate:sodium symporter activity
JWB57_RS04935	COG0583	DNA-binding transcription factor activity
JWB57_RS04945	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS04960	COG2186	Transcriptional regulator
JWB57_RS05020	COG0477	Major facilitator Superfamily
JWB57_RS05045	COG2995	paraquat-inducible protein a
JWB57_RS05050	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
JWB57_RS05050	COG3008	intermembrane lipid transfer
JWB57_RS05060	COG2351	hydroxyisourate hydrolase activity
JWB57_RS05100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JWB57_RS05110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
JWB57_RS05115	COG0642	Histidine kinase
JWB57_RS05120	COG0745	RESPONSE REGULATOR receiver
JWB57_RS05140	COG1794	racemase activity, acting on amino acids and derivatives
JWB57_RS05170	COG1301	dicarboxylic acid transport
JWB57_RS05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWB57_RS05185	COG2011	ABC-type metal ion transport system permease component
JWB57_RS05190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JWB57_RS05195	COG1464	Belongs to the NlpA lipoprotein family
JWB57_RS05200	COG0151	Belongs to the GarS family
JWB57_RS05205	COG0138	bifunctional purine biosynthesis protein purh
JWB57_RS05210	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
JWB57_RS05240	COG2308	Evidence 4 Homologs of previously reported genes of
JWB57_RS05250	COG1305	Transglutaminase-like
JWB57_RS05260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JWB57_RS05265	COG0305	Participates in initiation and elongation during chromosome replication
JWB57_RS05290	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
JWB57_RS05300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JWB57_RS05305	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JWB57_RS05330	COG1649	PFAM Uncharacterised BCR, COG1649
JWB57_RS05330	COG0726	polysaccharide deacetylase
JWB57_RS05335	COG1215	transferase activity, transferring glycosyl groups
JWB57_RS05340	COG3658	cytochrome
JWB57_RS05350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWB57_RS05365	COG0583	DNA-binding transcription factor activity
JWB57_RS05385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWB57_RS05390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWB57_RS05405	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS05410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JWB57_RS05415	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS05440	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
JWB57_RS05445	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
JWB57_RS05455	COG2205	protein histidine kinase activity
JWB57_RS05460	COG0745	RESPONSE REGULATOR receiver
JWB57_RS05465	COG0174	glutamine synthetase
JWB57_RS05485	COG0729	surface antigen
JWB57_RS05510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWB57_RS05515	COG2814	Major facilitator Superfamily
JWB57_RS05530	COG0583	DNA-binding transcription factor activity
JWB57_RS05545	COG1187	pseudouridine synthase activity
JWB57_RS05565	COG0802	atpase or kinase
JWB57_RS05570	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JWB57_RS05580	COG1923	regulation of RNA biosynthetic process
JWB57_RS05585	COG0697	spore germination
JWB57_RS05610	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JWB57_RS05615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JWB57_RS05615	COG0519	Catalyzes the synthesis of GMP from XMP
JWB57_RS05620	COG4302	ethanolamine ammonia-lyase activity
JWB57_RS05625	COG4303	Ethanolamine ammonia lyase large subunit
JWB57_RS05630	COG0531	amino acid
JWB57_RS05650	COG1454	alcohol dehydrogenase
JWB57_RS05655	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JWB57_RS05680	COG0308	aminopeptidase N
JWB57_RS05720	COG1605	Chorismate mutase
JWB57_RS05735	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JWB57_RS05750	COG1309	transcriptional regulator
JWB57_RS05760	COG0668	transmembrane transport
JWB57_RS05790	COG4773	Receptor
JWB57_RS05810	COG0488	(ABC) transporter
JWB57_RS05815	COG0589	response to stress
JWB57_RS05835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
JWB57_RS05845	COG3135	benzoate transporter
JWB57_RS05850	COG1522	sequence-specific DNA binding
JWB57_RS05860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JWB57_RS05865	COG0583	DNA-binding transcription factor activity
JWB57_RS05875	COG0183	Belongs to the thiolase family
JWB57_RS05885	COG2030	dehydratase
JWB57_RS05890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JWB57_RS05905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JWB57_RS05915	COG0824	Thioesterase
JWB57_RS05920	COG1454	alcohol dehydrogenase
JWB57_RS05930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JWB57_RS05950	COG0069	glutamate synthase activity
JWB57_RS05970	COG2814	Major facilitator Superfamily
JWB57_RS05985	COG0511	ligase activity, forming carbon-carbon bonds
JWB57_RS06005	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWB57_RS06005	COG1116	anion transmembrane transporter activity
JWB57_RS06010	COG0745	RESPONSE REGULATOR receiver
JWB57_RS06020	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWB57_RS06020	COG2146	nitrite reductase [NAD(P)H] activity
JWB57_RS06025	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWB57_RS06030	COG0243	molybdopterin cofactor binding
JWB57_RS06040	COG0243	molybdopterin cofactor binding
JWB57_RS06045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JWB57_RS06060	COG0521	Mo-molybdopterin cofactor biosynthetic process
JWB57_RS06060	COG0315	cyclic pyranopterin monophosphate synthase activity
JWB57_RS06065	COG0303	'Molybdopterin
JWB57_RS06080	COG0697	spore germination
JWB57_RS06100	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
JWB57_RS06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JWB57_RS06160	COG2204	response regulator
JWB57_RS06165	COG3852	Histidine kinase
JWB57_RS06190	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JWB57_RS06195	COG0575	Belongs to the CDS family
JWB57_RS06230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JWB57_RS06245	COG2137	regulation of response to DNA damage stimulus
JWB57_RS06255	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
JWB57_RS06260	COG1011	Hydrolase
JWB57_RS06285	COG1522	sequence-specific DNA binding
JWB57_RS06295	COG1113	amino acid transport
JWB57_RS06315	COG0659	secondary active sulfate transmembrane transporter activity
JWB57_RS06320	COG2135	peptidase activity
JWB57_RS06335	COG3300	MHYT domain
JWB57_RS06335	COG5001	Diguanylate cyclase
JWB57_RS06360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWB57_RS06360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
JWB57_RS06360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
JWB57_RS06365	COG1105	Belongs to the carbohydrate kinase PfkB family
JWB57_RS06370	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWB57_RS06370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JWB57_RS06405	COG0024	Methionine aminopeptidase
JWB57_RS06410	COG0583	DNA-binding transcription factor activity
JWB57_RS06420	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
JWB57_RS06425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JWB57_RS06430	COG0516	GMP reductase activity
JWB57_RS06430	COG0517	IMP dehydrogenase activity
JWB57_RS06455	COG0552	protein localization to endoplasmic reticulum
JWB57_RS06465	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
JWB57_RS06475	COG4890	Cyd operon protein YbgT
JWB57_RS06480	COG1294	oxidase, subunit
JWB57_RS06495	COG1585	Membrane protein implicated in regulation of membrane protease activity
JWB57_RS06505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JWB57_RS06510	COG4774	siderophore transport
JWB57_RS06525	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JWB57_RS06530	COG0569	domain protein
JWB57_RS06535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
JWB57_RS06565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
JWB57_RS06570	COG0542	response to heat
JWB57_RS06595	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWB57_RS06595	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS06640	COG2323	membrane
JWB57_RS06645	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
JWB57_RS06655	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JWB57_RS06660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JWB57_RS06665	COG0183	Belongs to the thiolase family
JWB57_RS06670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JWB57_RS06675	COG0596	Alpha beta hydrolase
JWB57_RS06680	COG2271	Major facilitator Superfamily
JWB57_RS06685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JWB57_RS06690	COG3485	protocatechuate 3,4-dioxygenase
JWB57_RS06695	COG3485	protocatechuate 3,4-dioxygenase
JWB57_RS06700	COG0710	3-dehydroquinate dehydratase activity
JWB57_RS06705	COG3420	alginic acid biosynthetic process
JWB57_RS06710	COG3659	wide pore channel activity
JWB57_RS06715	COG4993	Dehydrogenase
JWB57_RS06725	COG2391	methyltransferase activity
JWB57_RS06740	COG1414	Transcriptional regulator
JWB57_RS06745	COG0583	DNA-binding transcription factor activity
JWB57_RS06750	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS06775	COG2814	Major facilitator Superfamily
JWB57_RS06785	COG0154	amidase activity
JWB57_RS06805	COG4638	Rieske (2fe-2S)
JWB57_RS06815	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS06825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS06835	COG3733	amine oxidase
JWB57_RS06845	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS06855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JWB57_RS06860	COG0183	Belongs to the thiolase family
JWB57_RS06865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JWB57_RS06870	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JWB57_RS06880	COG4829	muconolactone delta-isomerase
JWB57_RS06885	COG4948	Mandelate Racemase Muconate Lactonizing
JWB57_RS06890	COG0583	DNA-binding transcription factor activity
JWB57_RS06900	COG2186	Transcriptional regulator
JWB57_RS06920	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS06935	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWB57_RS06935	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS06975	COG1309	transcriptional regulator
JWB57_RS06985	COG4221	oxidoreductase activity
JWB57_RS06990	COG4689	acetoacetate decarboxylase
JWB57_RS07000	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS07020	COG1335	isochorismatase
JWB57_RS07025	COG0583	DNA-binding transcription factor activity
JWB57_RS07035	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JWB57_RS07035	COG0475	glutathione-regulated potassium exporter activity
JWB57_RS07045	COG1473	amidohydrolase
JWB57_RS07105	COG2188	Transcriptional regulator
JWB57_RS07120	COG0583	DNA-binding transcription factor activity
JWB57_RS07135	COG1566	PFAM secretion protein HlyD family protein
JWB57_RS07150	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS07155	COG0129	dihydroxy-acid dehydratase activity
JWB57_RS07165	COG0583	DNA-binding transcription factor activity
JWB57_RS07170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
JWB57_RS07180	COG2084	Dehydrogenase
JWB57_RS07195	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JWB57_RS07255	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JWB57_RS07270	COG0556	nucleotide-excision repair
JWB57_RS07305	COG1073	alpha beta
JWB57_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS07330	COG2207	Transcriptional regulator
JWB57_RS07340	COG2205	protein histidine kinase activity
JWB57_RS07345	COG0745	RESPONSE REGULATOR receiver
JWB57_RS07350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS07355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JWB57_RS07360	COG1538	Outer membrane efflux protein
JWB57_RS07370	COG2072	flavoprotein involved in K transport
JWB57_RS07380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWB57_RS08085	COG3539	Fimbrial protein
JWB57_RS08110	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
JWB57_RS08120	COG0753	catalase activity
JWB57_RS08135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JWB57_RS08195	COG1535	isochorismatase
JWB57_RS08195	COG3433	isochorismatase activity
JWB57_RS08200	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS08205	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
JWB57_RS08210	COG4149	molybdate abc transporter
JWB57_RS08215	COG0725	ABC transporter, periplasmic molybdate-binding protein
JWB57_RS08225	COG4638	Rieske (2fe-2S)
JWB57_RS08230	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
JWB57_RS08235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWB57_RS08235	COG0543	2 iron, 2 sulfur cluster binding
JWB57_RS08250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS08260	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS08275	COG2207	Transcriptional regulator
JWB57_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS08285	COG2610	gluconate transmembrane transporter activity
JWB57_RS08295	COG0583	DNA-binding transcription factor activity
JWB57_RS08310	COG2031	fatty acid transporter
JWB57_RS08315	COG0183	Belongs to the thiolase family
JWB57_RS08320	COG0583	DNA-binding transcription factor activity
JWB57_RS08325	COG0583	DNA-binding transcription factor activity
JWB57_RS08340	COG1027	Aspartate ammonia-lyase
JWB57_RS08350	COG0477	Major facilitator Superfamily
JWB57_RS08370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWB57_RS08375	COG4521	taurine ABC transporter
JWB57_RS08390	COG2188	Transcriptional regulator
JWB57_RS08400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
JWB57_RS08405	COG1733	regulation of RNA biosynthetic process
JWB57_RS08410	COG2207	Transcriptional regulator
JWB57_RS08410	COG3708	Transcriptional regulator
JWB57_RS08425	COG0730	response to heat
JWB57_RS08440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWB57_RS08440	COG3453	Protein conserved in bacteria
JWB57_RS08450	COG3781	membrane
JWB57_RS08455	COG1063	alcohol dehydrogenase
JWB57_RS08465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JWB57_RS08470	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWB57_RS08475	COG0022	dehydrogenase e1 component
JWB57_RS08480	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JWB57_RS08485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JWB57_RS08500	COG3706	GGDEF domain
JWB57_RS08515	COG0133	tryptophan synthase activity
JWB57_RS08525	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JWB57_RS08560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JWB57_RS08585	COG2226	methyltransferase
JWB57_RS08640	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
JWB57_RS08645	COG4773	Receptor
JWB57_RS08665	COG0730	response to heat
JWB57_RS08670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
JWB57_RS08685	COG0406	alpha-ribazole phosphatase activity
JWB57_RS08690	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
JWB57_RS08705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWB57_RS08735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JWB57_RS08745	COG4264	IucA IucC family
JWB57_RS08750	COG4264	IucA IucC family
JWB57_RS08755	COG2814	Major facilitator Superfamily
JWB57_RS08770	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
JWB57_RS08785	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS08790	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS08795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
JWB57_RS08800	COG2207	Transcriptional regulator
JWB57_RS08805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JWB57_RS08810	COG0776	regulation of translation
JWB57_RS08835	COG0822	iron-sulfur transferase activity
JWB57_RS08840	COG0316	Belongs to the HesB IscA family
JWB57_RS08870	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
JWB57_RS08890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JWB57_RS08895	COG0702	epimerase
JWB57_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JWB57_RS08940	COG0339	signal peptide processing
JWB57_RS08960	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
JWB57_RS08985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JWB57_RS08990	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
JWB57_RS09020	COG0776	regulation of translation
JWB57_RS09085	COG0084	hydrolase, TatD family'
JWB57_RS09105	COG1663	tetraacyldisaccharide 4'-kinase activity
JWB57_RS09110	COG1132	(ABC) transporter
JWB57_RS09120	COG0811	peptide transport
JWB57_RS09125	COG1475	DNA binding
JWB57_RS09130	COG1192	Involved in chromosome partitioning
JWB57_RS09140	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
JWB57_RS09155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JWB57_RS09160	COG0191	fructose-bisphosphate aldolase activity
JWB57_RS09180	COG0424	maF-like protein
JWB57_RS09185	COG2850	peptidyl-arginine hydroxylation
JWB57_RS09195	COG0640	Transcriptional regulator
JWB57_RS09205	COG3619	membrane
JWB57_RS09210	COG3122	Protein conserved in bacteria
JWB57_RS09215	COG1132	(ABC) transporter
JWB57_RS09235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JWB57_RS09240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWB57_RS09250	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JWB57_RS09250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
JWB57_RS09250	COG0506	proline dehydrogenase activity
JWB57_RS09255	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
JWB57_RS09270	COG3698	Phosphodiester glycosidase
JWB57_RS09280	COG2353	YceI-like domain
JWB57_RS09290	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
JWB57_RS09335	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JWB57_RS09335	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JWB57_RS09360	COG3539	Fimbrial protein
JWB57_RS09365	COG3121	Chaperone
JWB57_RS09390	COG0697	spore germination
JWB57_RS09400	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JWB57_RS09410	COG0583	DNA-binding transcription factor activity
JWB57_RS09445	COG1522	sequence-specific DNA binding
JWB57_RS09455	COG1126	abc transporter atp-binding protein
JWB57_RS09460	COG0765	amino acid transport
JWB57_RS09465	COG0765	amino acid transport
JWB57_RS09495	COG1464	Belongs to the NlpA lipoprotein family
JWB57_RS09505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JWB57_RS09510	COG2011	ABC-type metal ion transport system permease component
JWB57_RS09515	COG0012	GTP binding
JWB57_RS09540	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JWB57_RS09580	COG0386	Belongs to the glutathione peroxidase family
JWB57_RS09590	COG0436	Aminotransferase
JWB57_RS09595	COG1301	dicarboxylic acid transport
JWB57_RS09630	COG3634	alkyl hydroperoxide reductase activity
JWB57_RS09645	COG0583	DNA-binding transcription factor activity
JWB57_RS09650	COG0798	PFAM Bile acid sodium symporter
JWB57_RS09655	COG0640	Transcriptional regulator
JWB57_RS09670	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
JWB57_RS09680	COG0583	DNA-binding transcription factor activity
JWB57_RS09690	COG1953	Uracil, thiamine, allantoin
JWB57_RS09700	COG2175	clavaminate synthase activity
JWB57_RS09705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWB57_RS09710	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
JWB57_RS09715	COG4521	taurine ABC transporter
JWB57_RS09725	COG0477	Major facilitator Superfamily
JWB57_RS09745	COG1271	oxidase subunit
JWB57_RS09750	COG1294	oxidase, subunit
JWB57_RS09760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWB57_RS09780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JWB57_RS09800	COG3052	prosthetic group binding
JWB57_RS09805	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
JWB57_RS09815	COG2814	Major facilitator Superfamily
JWB57_RS09830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWB57_RS09835	COG1346	cytolysis
JWB57_RS09845	COG0583	DNA-binding transcription factor activity
JWB57_RS09850	COG0625	glutathione transferase activity
JWB57_RS09855	COG0625	glutathione transferase activity
JWB57_RS09860	COG0583	DNA-binding transcription factor activity
JWB57_RS09875	COG1045	serine acetyltransferase
JWB57_RS09880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JWB57_RS09885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JWB57_RS09895	COG1280	lysine exporter protein (LysE YggA)
JWB57_RS09910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWB57_RS09915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWB57_RS09920	COG1126	abc transporter atp-binding protein
JWB57_RS09925	COG0765	amino acid transport
JWB57_RS09930	COG0765	amino acid transport
JWB57_RS09950	COG0784	Response regulator, receiver
JWB57_RS09950	COG2205	protein histidine kinase activity
JWB57_RS09995	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS10045	COG0583	DNA-binding transcription factor activity
JWB57_RS10065	COG0318	PFAM AMP-dependent synthetase and ligase
JWB57_RS10070	COG1309	transcriptional regulator
JWB57_RS10075	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS10080	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JWB57_RS10085	COG1024	Enoyl-CoA hydratase
JWB57_RS10090	COG4770	biotin carboxylase activity
JWB57_RS10100	COG0583	DNA-binding transcription factor activity
JWB57_RS10115	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS10125	COG2814	Major facilitator Superfamily
JWB57_RS10135	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
JWB57_RS10140	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
JWB57_RS10145	COG2814	Major facilitator Superfamily
JWB57_RS10150	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS10155	COG1024	Enoyl-CoA hydratase
JWB57_RS10160	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS10165	COG1250	3-hydroxyacyl-CoA dehydrogenase
JWB57_RS10170	COG0183	Belongs to the thiolase family
JWB57_RS10180	COG2814	Major facilitator Superfamily
JWB57_RS10190	COG1024	Enoyl-CoA hydratase
JWB57_RS10200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JWB57_RS10205	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS10210	COG2814	Major facilitator Superfamily
JWB57_RS10215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
JWB57_RS10220	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JWB57_RS10235	COG3842	ATPase activity
JWB57_RS10240	COG1840	ABC-type Fe3 transport system, periplasmic component
JWB57_RS10250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWB57_RS10255	COG1414	Transcriptional regulator
JWB57_RS10265	COG0583	DNA-binding transcription factor activity
JWB57_RS10270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
JWB57_RS10275	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS10285	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
JWB57_RS10295	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS10300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWB57_RS10305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS10310	COG2267	carboxylic ester hydrolase activity
JWB57_RS10330	COG3038	cytochrome b561
JWB57_RS10335	COG0753	catalase activity
JWB57_RS10340	COG2271	Major facilitator Superfamily
JWB57_RS10345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JWB57_RS10350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JWB57_RS10380	COG1278	Cold shock
JWB57_RS10415	COG0210	DNA helicase
JWB57_RS10425	COG2050	protein possibly involved in aromatic compounds catabolism
JWB57_RS10435	COG3327	negative regulation of DNA-templated transcription, initiation
JWB57_RS10440	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JWB57_RS10445	COG0183	Belongs to the thiolase family
JWB57_RS10450	COG1250	3-hydroxyacyl-CoA dehydrogenase
JWB57_RS10455	COG1024	Enoyl-CoA hydratase
JWB57_RS10460	COG1024	Enoyl-CoA hydratase
JWB57_RS10465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWB57_RS10470	COG2151	metal-sulfur cluster biosynthetic enzyme
JWB57_RS10475	COG3396	Phenylacetate-CoA oxygenase
JWB57_RS10480	COG3460	Phenylacetate-CoA oxygenase
JWB57_RS10485	COG3396	Phenylacetate-CoA oxygenase
JWB57_RS10490	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS10490	COG2030	dehydratase
JWB57_RS10495	COG1760	l-serine dehydratase
JWB57_RS10505	COG0531	amino acid
JWB57_RS10510	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS10535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JWB57_RS10555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWB57_RS10565	COG0789	Transcriptional regulator
JWB57_RS10575	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JWB57_RS10590	COG2807	transmembrane transport
JWB57_RS10595	COG0590	tRNA wobble adenosine to inosine editing
JWB57_RS10715	COG1116	anion transmembrane transporter activity
JWB57_RS10720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JWB57_RS10730	COG0864	Transcriptional regulator
JWB57_RS10740	COG1733	regulation of RNA biosynthetic process
JWB57_RS10745	COG2249	NAD(P)H dehydrogenase (quinone) activity
JWB57_RS10750	COG0439	Biotin carboxylase
JWB57_RS10765	COG1063	alcohol dehydrogenase
JWB57_RS10775	COG1309	transcriptional regulator
JWB57_RS10800	COG0038	chloride channel
JWB57_RS10805	COG4770	biotin carboxylase activity
JWB57_RS10825	COG1914	H( )-stimulated, divalent metal cation uptake system
JWB57_RS10830	COG0583	DNA-binding transcription factor activity
JWB57_RS10850	COG3209	COG3209 Rhs family protein
JWB57_RS10895	COG1250	3-hydroxyacyl-CoA dehydrogenase
JWB57_RS10915	COG2814	Major facilitator Superfamily
JWB57_RS10930	COG1560	Kdo2-lipid A biosynthetic process
JWB57_RS10940	COG5006	permease, DMT superfamily
JWB57_RS10945	COG1522	sequence-specific DNA binding
JWB57_RS10960	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JWB57_RS10970	COG4122	O-methyltransferase activity
JWB57_RS11000	COG1538	Outer membrane efflux protein
JWB57_RS11005	COG1137	ATPase activity
JWB57_RS11010	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
JWB57_RS11020	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
JWB57_RS11085	COG5434	Belongs to the glycosyl hydrolase 28 family
JWB57_RS11100	COG3566	protein conserved in bacteria
JWB57_RS11120	COG3567	Phage-associated protein, HI1409 family
JWB57_RS11125	COG5410	chromosome segregation
JWB57_RS11195	COG2814	Major facilitator Superfamily
JWB57_RS11230	COG1278	Cold shock
JWB57_RS11265	COG1570	exodeoxyribonuclease VII activity
JWB57_RS11315	COG0583	DNA-binding transcription factor activity
JWB57_RS11325	COG4638	Rieske (2fe-2S)
JWB57_RS11335	COG0543	2 iron, 2 sulfur cluster binding
JWB57_RS11335	COG0633	Ferredoxin
JWB57_RS11340	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS11345	COG3135	benzoate transporter
JWB57_RS11350	COG2814	Major facilitator Superfamily
JWB57_RS11365	COG1643	Atp-dependent helicase
JWB57_RS11370	COG0450	alkyl hydroperoxide reductase
JWB57_RS11380	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
JWB57_RS11390	COG3634	alkyl hydroperoxide reductase activity
JWB57_RS11410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JWB57_RS11415	COG0625	glutathione transferase activity
JWB57_RS11425	COG2885	chlorophyll binding
JWB57_RS11460	COG0542	response to heat
JWB57_RS11475	COG1765	OsmC-like protein
JWB57_RS11490	COG0667	Aldo Keto reductase
JWB57_RS11505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JWB57_RS11515	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
JWB57_RS11525	COG0527	aspartate kinase activity
JWB57_RS11535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JWB57_RS11545	COG3038	cytochrome b561
JWB57_RS11550	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
JWB57_RS11555	COG2252	PERMEase
JWB57_RS11565	COG2072	flavoprotein involved in K transport
JWB57_RS11580	COG1741	Belongs to the pirin family
JWB57_RS11585	COG1309	transcriptional regulator
JWB57_RS11595	COG0300	oxidoreductase activity
JWB57_RS11600	COG2072	flavoprotein involved in K transport
JWB57_RS11605	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
JWB57_RS11650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWB57_RS11665	COG2814	Major facilitator Superfamily
JWB57_RS11670	COG1024	Enoyl-CoA hydratase
JWB57_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS11685	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS11710	COG2186	Transcriptional regulator
JWB57_RS11715	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS11725	COG4948	Mandelate Racemase Muconate Lactonizing
JWB57_RS11730	COG2271	Major facilitator Superfamily
JWB57_RS11735	COG2721	sulfolactate sulfo-lyase activity
JWB57_RS11740	COG0697	spore germination
JWB57_RS11790	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS11810	COG0531	amino acid
JWB57_RS11820	COG1113	amino acid transport
JWB57_RS11855	COG3209	COG3209 Rhs family protein
JWB57_RS11890	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWB57_RS11890	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS11900	COG5001	Diguanylate cyclase
JWB57_RS11900	COG4251	negative regulation of phosphorylation
JWB57_RS11900	COG3706	GGDEF domain
JWB57_RS11900	COG2203	Gaf domain
JWB57_RS11910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWB57_RS11960	COG4172	Belongs to the ABC transporter superfamily
JWB57_RS11965	COG4239	(ABC) transporter, permease
JWB57_RS11970	COG4174	ABC transporter (Permease)
JWB57_RS11980	COG1388	LysM domain
JWB57_RS11980	COG0741	lytic transglycosylase activity
JWB57_RS11980	COG0741	lytic transglycosylase activity
JWB57_RS11980	COG1388	LysM domain
JWB57_RS11985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JWB57_RS12025	COG0583	DNA-binding transcription factor activity
JWB57_RS12030	COG1279	arginine transmembrane transporter activity
JWB57_RS12050	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWB57_RS12055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWB57_RS12060	COG0006	proline dipeptidase activity
JWB57_RS12100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JWB57_RS12120	COG3384	dioxygenase
JWB57_RS12130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JWB57_RS12135	COG2878	Part of a membrane complex involved in electron transport
JWB57_RS12140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
JWB57_RS12165	COG0768	penicillin binding
JWB57_RS12170	COG0742	ribosomal rna small subunit methyltransferase
JWB57_RS12185	COG0830	nickel cation binding
JWB57_RS12195	COG0804	urea catabolic process
JWB57_RS12235	COG1253	flavin adenine dinucleotide binding
JWB57_RS12240	COG2851	Citrate transporter
JWB57_RS12290	COG1773	rubredoxin
JWB57_RS12295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JWB57_RS12305	COG0583	DNA-binding transcription factor activity
JWB57_RS12335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
JWB57_RS12340	COG4181	ATPase activity
JWB57_RS12385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
JWB57_RS12405	COG0306	phosphate transporter
JWB57_RS12415	COG3958	Transketolase
JWB57_RS12420	COG3959	Transketolase, thiamine diphosphate binding domain
JWB57_RS12425	COG2271	Major facilitator Superfamily
JWB57_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS12435	COG0583	DNA-binding transcription factor activity
JWB57_RS12450	COG2223	nitrite transmembrane transporter activity
JWB57_RS12455	COG2207	Transcriptional regulator
JWB57_RS12460	COG2066	Belongs to the glutaminase family
JWB57_RS12465	COG0242	peptide deformylase activity
JWB57_RS12470	COG0477	Major facilitator Superfamily
JWB57_RS12480	COG0028	Belongs to the TPP enzyme family
JWB57_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS12500	COG2267	carboxylic ester hydrolase activity
JWB57_RS12510	COG2271	Major facilitator Superfamily
JWB57_RS12515	COG0446	pyridine nucleotide-disulphide oxidoreductase
JWB57_RS12525	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS12545	COG1414	Transcriptional regulator
JWB57_RS12560	COG1024	Enoyl-CoA hydratase
JWB57_RS12570	COG1215	transferase activity, transferring glycosyl groups
JWB57_RS12575	COG0726	polysaccharide deacetylase
JWB57_RS12575	COG1649	PFAM Uncharacterised BCR, COG1649
JWB57_RS12585	COG4681	YaeQ
JWB57_RS12595	COG0523	cobalamin synthesis protein
JWB57_RS12605	COG1607	acyl-coa hydrolase
JWB57_RS12615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWB57_RS12620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWB57_RS12625	COG1309	transcriptional regulator
JWB57_RS12650	COG2040	homocysteine
JWB57_RS12655	COG0531	amino acid
JWB57_RS12710	COG1595	DNA-templated transcription, initiation
JWB57_RS12720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWB57_RS12725	COG0477	Major facilitator Superfamily
JWB57_RS12785	COG3177	Filamentation induced by cAMP protein fic
JWB57_RS12790	COG0629	single-stranded DNA binding
JWB57_RS12845	COG0582	viral genome integration into host DNA
JWB57_RS12855	COG0405	Gamma-glutamyltransferase
JWB57_RS12860	COG2814	Major facilitator Superfamily
JWB57_RS12870	COG2050	protein possibly involved in aromatic compounds catabolism
JWB57_RS12885	COG1090	epimerase
JWB57_RS12905	COG0420	3'-5' exonuclease activity
JWB57_RS12930	COG0735	belongs to the Fur family
JWB57_RS12935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JWB57_RS12955	COG0121	glutamine amidotransferase
JWB57_RS12970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JWB57_RS12980	COG0210	DNA helicase
JWB57_RS12985	COG2885	chlorophyll binding
JWB57_RS12990	COG0204	Acyl-transferase
JWB57_RS13005	COG2894	cell division
JWB57_RS13020	COG1280	lysine exporter protein (LysE YggA)
JWB57_RS13025	COG1674	ftsk spoiiie
JWB57_RS13025	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
JWB57_RS13030	COG0492	ferredoxin-NADP+ reductase activity
JWB57_RS13035	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
JWB57_RS13045	COG0456	acetyltransferase
JWB57_RS13090	COG1981	membrane
JWB57_RS13105	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JWB57_RS13105	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JWB57_RS13125	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS13135	COG0657	acetylesterase activity
JWB57_RS13145	COG0473	3-isopropylmalate dehydrogenase activity
JWB57_RS13150	COG0583	DNA-binding transcription factor activity
JWB57_RS13170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
JWB57_RS13195	COG0564	pseudouridine synthase activity
JWB57_RS13205	COG0358	DNA primase activity
JWB57_RS13220	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
JWB57_RS13250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JWB57_RS13280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JWB57_RS13290	COG0351	phosphomethylpyrimidine kinase
JWB57_RS13290	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JWB57_RS13290	COG0352	thiamine-phosphate diphosphorylase activity
JWB57_RS13295	COG1652	LysM domain
JWB57_RS13320	COG1399	metal-binding, possibly nucleic acid-binding protein
JWB57_RS13325	COG3101	peptidyl-lysine hydroxylation
JWB57_RS13330	COG0009	L-threonylcarbamoyladenylate synthase
JWB57_RS13335	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
JWB57_RS13340	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JWB57_RS13355	COG4106	trans-aconitate 2-methyltransferase activity
JWB57_RS13370	COG0596	Alpha beta hydrolase
JWB57_RS13370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JWB57_RS13370	COG2226	methyltransferase
JWB57_RS13380	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JWB57_RS13385	COG2223	nitrite transmembrane transporter activity
JWB57_RS13405	COG1196	nuclear chromosome segregation
JWB57_RS13415	COG0730	response to heat
JWB57_RS13430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
JWB57_RS13440	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JWB57_RS13490	COG0489	protein tyrosine kinase activity
JWB57_RS13500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWB57_RS13500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWB57_RS13530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
JWB57_RS13535	COG2081	HI0933 family
JWB57_RS13545	COG0668	transmembrane transport
JWB57_RS13565	COG0583	DNA-binding transcription factor activity
JWB57_RS13590	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JWB57_RS13595	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JWB57_RS13625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JWB57_RS13665	COG0745	RESPONSE REGULATOR receiver
JWB57_RS13685	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JWB57_RS13695	COG0384	phenazine biosynthesis protein PhzF
JWB57_RS13720	COG1309	transcriptional regulator
JWB57_RS13725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS13740	COG0583	DNA-binding transcription factor activity
JWB57_RS13770	COG0583	DNA-binding transcription factor activity
JWB57_RS13785	COG0583	DNA-binding transcription factor activity
JWB57_RS13790	COG1053	succinate dehydrogenase
JWB57_RS13800	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JWB57_RS13805	COG2814	Major facilitator Superfamily
JWB57_RS13810	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS13815	COG0583	DNA-binding transcription factor activity
JWB57_RS13820	COG1063	alcohol dehydrogenase
JWB57_RS13850	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JWB57_RS13855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JWB57_RS13860	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JWB57_RS13875	COG3667	copper resistance
JWB57_RS13880	COG2132	Multicopper oxidase
JWB57_RS13890	COG0561	phosphatase activity
JWB57_RS13895	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JWB57_RS13905	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
JWB57_RS13920	COG1214	PFAM Peptidase M22, glycoprotease
JWB57_RS13980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JWB57_RS13985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JWB57_RS13990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JWB57_RS14050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JWB57_RS14060	COG1846	Transcriptional regulator
JWB57_RS14065	COG1764	response to oxidative stress
JWB57_RS14105	COG0037	tRNA processing
JWB57_RS14115	COG0248	Ppx GppA phosphatase
JWB57_RS14145	COG0072	phenylalanine-tRNA ligase activity
JWB57_RS14185	COG1238	metal cluster binding
JWB57_RS14190	COG0625	glutathione transferase activity
JWB57_RS14205	COG0318	PFAM AMP-dependent synthetase and ligase
JWB57_RS14210	COG3028	Belongs to the UPF0307 family
JWB57_RS14215	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
JWB57_RS14235	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JWB57_RS14240	COG0617	tRNA 3'-terminal CCA addition
JWB57_RS14245	COG1555	photosystem II stabilization
JWB57_RS14250	COG3956	TIGRFAM MazG family protein
JWB57_RS14260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JWB57_RS14280	COG0784	Response regulator, receiver
JWB57_RS14280	COG2205	protein histidine kinase activity
JWB57_RS14280	COG5002	protein histidine kinase activity
JWB57_RS14285	COG1024	Enoyl-CoA hydratase
JWB57_RS14290	COG2084	Dehydrogenase
JWB57_RS14295	COG3622	Belongs to the hyi family
JWB57_RS14325	COG0697	spore germination
JWB57_RS14335	COG2814	Major facilitator Superfamily
JWB57_RS14355	COG2132	Multicopper oxidase
JWB57_RS14370	COG2205	protein histidine kinase activity
JWB57_RS14455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JWB57_RS14465	COG0583	DNA-binding transcription factor activity
JWB57_RS14475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
JWB57_RS14485	COG0084	hydrolase, TatD family'
JWB57_RS14500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
JWB57_RS14530	COG0440	acetolactate synthase activity
JWB57_RS14535	COG0028	Belongs to the TPP enzyme family
JWB57_RS14560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS14565	COG1136	(ABC) transporter
JWB57_RS14565	COG0577	efflux transmembrane transporter activity
JWB57_RS14570	COG1538	Outer membrane efflux protein
JWB57_RS14585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
JWB57_RS14590	COG1162	GTPase activity
JWB57_RS14600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
JWB57_RS14640	COG1426	Protein conserved in bacteria
JWB57_RS14675	COG0793	Belongs to the peptidase S41A family
JWB57_RS14690	COG2267	carboxylic ester hydrolase activity
JWB57_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS14705	COG3265	gluconokinase activity
JWB57_RS14715	COG0800	Aldolase
JWB57_RS14725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
JWB57_RS14730	COG0857	belongs to the CobB CobQ family
JWB57_RS14730	COG0280	phosphate acetyltransferase
JWB57_RS14735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
JWB57_RS14735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
JWB57_RS14755	COG0740	serine-type endopeptidase activity
JWB57_RS14765	COG4774	siderophore transport
JWB57_RS14775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JWB57_RS14785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JWB57_RS14785	COG2813	Specifically methylates the guanine in position
JWB57_RS14885	COG0788	formyltetrahydrofolate deformylase activity
JWB57_RS14910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JWB57_RS14910	COG4651	solute:proton antiporter activity
JWB57_RS14930	COG0724	RNA recognition motif
JWB57_RS14935	COG0210	DNA helicase
JWB57_RS14960	COG1733	regulation of RNA biosynthetic process
JWB57_RS14970	COG2900	Belongs to the SlyX family
JWB57_RS14975	COG0488	(ABC) transporter
JWB57_RS14980	COG1280	lysine exporter protein (LysE YggA)
JWB57_RS14985	COG1560	Kdo2-lipid A biosynthetic process
JWB57_RS14995	COG1301	dicarboxylic acid transport
JWB57_RS15050	COG0473	3-isopropylmalate dehydrogenase activity
JWB57_RS15105	COG0583	DNA-binding transcription factor activity
JWB57_RS15115	COG0625	glutathione transferase activity
JWB57_RS15120	COG2378	regulation of single-species biofilm formation
JWB57_RS15125	COG0546	phosphoglycolate phosphatase activity
JWB57_RS15140	COG1530	ribonuclease E activity
JWB57_RS15145	COG0318	PFAM AMP-dependent synthetase and ligase
JWB57_RS15160	COG0583	DNA-binding transcription factor activity
JWB57_RS15165	COG4221	oxidoreductase activity
JWB57_RS15170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JWB57_RS15180	COG0534	Mate efflux family protein
JWB57_RS15195	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
JWB57_RS15220	COG0493	'glutamate synthase
JWB57_RS15220	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
JWB57_RS15230	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
JWB57_RS15235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JWB57_RS15250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JWB57_RS15260	COG0644	oxidoreductase
JWB57_RS15260	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
JWB57_RS15270	COG0425	Belongs to the sulfur carrier protein TusA family
JWB57_RS15275	COG4535	Mg2 and Co2 transporter CorC
JWB57_RS15285	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JWB57_RS15305	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JWB57_RS15310	COG0475	glutathione-regulated potassium exporter activity
JWB57_RS15310	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JWB57_RS15325	COG0484	heat shock protein binding
JWB57_RS15330	COG0789	Transcriptional regulator
JWB57_RS15335	COG0598	Magnesium transport protein CorA
JWB57_RS15350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
JWB57_RS15355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
JWB57_RS15360	COG1074	ATP-dependent DNA helicase activity
JWB57_RS15365	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
JWB57_RS15385	COG2226	methyltransferase
JWB57_RS15400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWB57_RS15405	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JWB57_RS15420	COG2111	Na H antiporter
JWB57_RS15420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JWB57_RS15425	COG1006	Multisubunit Na H antiporter MnhC subunit
JWB57_RS15430	COG0651	ATP synthesis coupled electron transport
JWB57_RS15435	COG1863	multisubunit Na H antiporter MnhE subunit
JWB57_RS15440	COG2212	antiporter activity
JWB57_RS15445	COG1320	monovalent cation:proton antiporter activity
JWB57_RS15460	COG0195	Participates in both transcription termination and antitermination
JWB57_RS15510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JWB57_RS15515	COG0237	dephospho-CoA kinase activity
JWB57_RS15525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JWB57_RS15540	COG0497	DNA recombination
JWB57_RS15550	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JWB57_RS15580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JWB57_RS15580	COG2169	Transcriptional regulator
JWB57_RS15585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
JWB57_RS15645	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
JWB57_RS15660	COG0326	Molecular chaperone. Has ATPase activity
JWB57_RS15675	COG2056	Na+-H+ antiporter family
JWB57_RS15775	COG0546	phosphoglycolate phosphatase activity
JWB57_RS15780	COG1716	ATPase activity
JWB57_RS15830	COG0181	hydroxymethylbilane synthase activity
JWB57_RS15840	COG3275	phosphorelay sensor kinase activity
JWB57_RS15860	COG1538	Outer membrane efflux protein
JWB57_RS15865	COG0697	spore germination
JWB57_RS15890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
JWB57_RS15895	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
JWB57_RS15900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JWB57_RS15905	COG0772	Belongs to the SEDS family
JWB57_RS15930	COG4974	Belongs to the 'phage' integrase family
JWB57_RS15935	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JWB57_RS15945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JWB57_RS15955	COG2197	response regulator
JWB57_RS15970	COG0793	Belongs to the peptidase S41A family
JWB57_RS15975	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
JWB57_RS15980	COG0795	lipopolysaccharide-transporting ATPase activity
JWB57_RS16020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JWB57_RS16020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JWB57_RS16030	COG0004	ammonium transporteR
JWB57_RS16035	COG0347	Belongs to the P(II) protein family
JWB57_RS16055	COG0659	secondary active sulfate transmembrane transporter activity
JWB57_RS16080	COG0789	Transcriptional regulator
JWB57_RS16095	COG0640	Transcriptional regulator
JWB57_RS16105	COG0798	PFAM Bile acid sodium symporter
JWB57_RS16110	COG0431	NADPH-dependent FMN reductase
JWB57_RS16115	COG0492	ferredoxin-NADP+ reductase activity
JWB57_RS16120	COG2072	flavoprotein involved in K transport
JWB57_RS16155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWB57_RS16165	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWB57_RS16185	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JWB57_RS16200	COG0318	PFAM AMP-dependent synthetase and ligase
JWB57_RS16210	COG0477	Major facilitator Superfamily
JWB57_RS16215	COG2860	membrane
JWB57_RS16220	COG3012	SEC-C Motif Domain Protein
JWB57_RS16225	COG1253	flavin adenine dinucleotide binding
JWB57_RS16235	COG0477	Major facilitator Superfamily
JWB57_RS16245	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWB57_RS16285	COG0655	NAD(P)H dehydrogenase (quinone) activity
JWB57_RS16295	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JWB57_RS16365	COG0758	DNA mediated transformation
JWB57_RS16375	COG0697	spore germination
JWB57_RS16380	COG1309	transcriptional regulator
JWB57_RS16395	COG0386	Belongs to the glutathione peroxidase family
JWB57_RS16460	COG1121	(ABC) transporter
JWB57_RS16465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JWB57_RS16470	COG1280	lysine exporter protein (LysE YggA)
JWB57_RS16475	COG2837	iron assimilation
JWB57_RS16480	COG0281	malic enzyme
JWB57_RS16525	COG0519	Catalyzes the synthesis of GMP from XMP
JWB57_RS16525	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JWB57_RS16530	COG4399	Belongs to the UPF0754 family
JWB57_RS16535	COG2259	Doxx family
JWB57_RS16540	COG0586	Pfam SNARE associated Golgi protein
JWB57_RS16555	COG1192	Involved in chromosome partitioning
JWB57_RS16565	COG0271	Belongs to the BolA IbaG family
JWB57_RS16585	COG2267	carboxylic ester hydrolase activity
JWB57_RS16605	COG3321	synthase
JWB57_RS16605	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
JWB57_RS16605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JWB57_RS16605	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
JWB57_RS16610	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS16620	COG2197	response regulator
JWB57_RS16630	COG3916	Acyl-homoserine-lactone synthase
JWB57_RS16635	COG0477	Major facilitator Superfamily
JWB57_RS16640	COG1024	Enoyl-CoA hydratase
JWB57_RS16645	COG1024	Enoyl-CoA hydratase
JWB57_RS16650	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS16655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JWB57_RS16675	COG1113	amino acid transport
JWB57_RS16680	COG1113	amino acid transport
JWB57_RS16685	COG0251	oxidation-reduction process
JWB57_RS16725	COG0564	pseudouridine synthase activity
JWB57_RS16740	COG3328	transposase activity
JWB57_RS16770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JWB57_RS16785	COG1802	Transcriptional regulator
JWB57_RS16795	COG1448	Aminotransferase
JWB57_RS16800	COG0277	FAD linked oxidase domain protein
JWB57_RS16810	COG2186	Transcriptional regulator
JWB57_RS16820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JWB57_RS16825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
JWB57_RS16840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
JWB57_RS16850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
JWB57_RS16905	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JWB57_RS16910	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JWB57_RS16915	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
JWB57_RS16945	COG0728	peptidoglycan biosynthetic process
JWB57_RS16950	COG3023	N-Acetylmuramoyl-L-alanine amidase
JWB57_RS17005	COG0546	phosphoglycolate phosphatase activity
JWB57_RS17010	COG1028	Short-chain dehydrogenase reductase Sdr
JWB57_RS17030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWB57_RS17035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
JWB57_RS17040	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JWB57_RS17045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
JWB57_RS17050	COG1116	anion transmembrane transporter activity
JWB57_RS17055	COG1309	transcriptional regulator
JWB57_RS17060	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JWB57_RS17070	COG0196	riboflavin kinase activity
JWB57_RS17075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JWB57_RS17085	COG1047	Peptidyl-prolyl cis-trans
JWB57_RS17125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
JWB57_RS17130	COG0657	acetylesterase activity
JWB57_RS17150	COG0583	DNA-binding transcription factor activity
JWB57_RS17180	COG2951	lytic endotransglycosylase activity
JWB57_RS17185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
JWB57_RS17200	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JWB57_RS17210	COG0671	phosphoesterase, PA-phosphatase related
JWB57_RS17215	COG0861	Integral membrane protein TerC family
JWB57_RS17225	COG0754	glutathionylspermidine amidase activity
JWB57_RS17235	COG0402	S-adenosylhomocysteine deaminase activity
JWB57_RS17250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JWB57_RS17255	COG1230	cation diffusion facilitator family transporter
JWB57_RS17270	COG0706	membrane insertase activity
JWB57_RS17295	COG0592	DNA-directed DNA polymerase activity
JWB57_RS17305	COG0187	DNA topoisomerase II activity
JWB57_RS17315	COG0586	Pfam SNARE associated Golgi protein
JWB57_RS17320	COG0488	(ABC) transporter
JWB57_RS17345	COG0596	Alpha beta hydrolase
JWB57_RS17350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
JWB57_RS17355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JWB57_RS17395	COG0733	neurotransmitter:sodium symporter activity
JWB57_RS17430	COG0583	DNA-binding transcription factor activity
JWB57_RS17435	COG2233	PERMEase
JWB57_RS17450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JWB57_RS17485	COG2814	Major facilitator Superfamily
JWB57_RS17490	COG0656	L-ascorbic acid biosynthetic process
JWB57_RS17495	COG0583	DNA-binding transcription factor activity
JWB57_RS17510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JWB57_RS17515	COG1064	alcohol dehydrogenase
JWB57_RS17520	COG2818	Glycosylase
JWB57_RS17535	COG1194	a g-specific adenine glycosylase
JWB57_RS17555	COG2983	Belongs to the UPF0260 family
JWB57_RS17560	COG2133	pyrroloquinoline quinone binding
JWB57_RS17565	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JWB57_RS17570	COG2116	formate transmembrane transporter activity
JWB57_RS17590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JWB57_RS17595	COG1335	isochorismatase
JWB57_RS17600	COG0385	Bile acid
JWB57_RS17605	COG0534	Mate efflux family protein
JWB57_RS17610	COG1683	Conserved Protein
JWB57_RS17630	COG0625	glutathione transferase activity
JWB57_RS17640	COG1113	amino acid transport
JWB57_RS17650	COG0523	cobalamin synthesis protein
JWB57_RS17660	COG2188	Transcriptional regulator
JWB57_RS17690	COG0010	Belongs to the arginase family
JWB57_RS17705	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JWB57_RS17735	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JWB57_RS17745	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
JWB57_RS17750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
JWB57_RS17835	COG0534	Mate efflux family protein
JWB57_RS17840	COG0436	Aminotransferase
JWB57_RS17845	COG2733	membrane
JWB57_RS17860	COG2918	glutathione biosynthetic process
JWB57_RS17875	COG5632	N-Acetylmuramoyl-L-alanine amidase
JWB57_RS17875	COG3409	Peptidoglycan-binding domain 1 protein
JWB57_RS17875	COG1388	LysM domain
JWB57_RS17910	COG3150	esterase
JWB57_RS17920	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
JWB57_RS17930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
JWB57_RS17940	COG2233	PERMEase
JWB57_RS17945	COG2351	hydroxyisourate hydrolase activity
JWB57_RS17980	COG3706	GGDEF domain
JWB57_RS17995	COG1393	Belongs to the ArsC family
JWB57_RS18000	COG0708	Exodeoxyribonuclease III
JWB57_RS18020	COG0189	ligase activity
JWB57_RS18040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
JWB57_RS18050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
JWB57_RS18065	COG4942	peptidase
JWB57_RS18075	COG0508	dehydrogenase complex catalyzes the overall conversion of
JWB57_RS18085	COG2119	membrane
JWB57_RS18090	COG4774	siderophore transport
JWB57_RS18095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JWB57_RS18095	COG0426	domain, Protein
JWB57_RS18120	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JWB57_RS18140	COG1902	pentaerythritol trinitrate reductase activity
JWB57_RS18145	COG1519	Transferase
JWB57_RS18150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JWB57_RS18155	COG0668	transmembrane transport
JWB57_RS18165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JWB57_RS18170	COG1335	isochorismatase
JWB57_RS18175	COG1522	sequence-specific DNA binding
JWB57_RS18200	COG0784	Response regulator, receiver
JWB57_RS18200	COG2198	Histidine kinase
JWB57_RS18200	COG2205	protein histidine kinase activity
JWB57_RS18205	COG3162	membrane
JWB57_RS18210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JWB57_RS18220	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
JWB57_RS18235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JWB57_RS18240	COG1309	transcriptional regulator
JWB57_RS18260	COG0352	thiamine-phosphate diphosphorylase activity
JWB57_RS18260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
JWB57_RS18260	COG0351	phosphomethylpyrimidine kinase
JWB57_RS18270	COG2814	Major facilitator Superfamily
JWB57_RS18285	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
JWB57_RS18295	COG1113	amino acid transport
JWB57_RS18305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JWB57_RS18310	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS18320	COG1335	isochorismatase
JWB57_RS18350	COG2814	Major facilitator Superfamily
JWB57_RS18355	COG0583	DNA-binding transcription factor activity
JWB57_RS18375	COG0667	Aldo Keto reductase
JWB57_RS18395	COG1733	regulation of RNA biosynthetic process
JWB57_RS18410	COG1733	regulation of RNA biosynthetic process
JWB57_RS18415	COG2249	NAD(P)H dehydrogenase (quinone) activity
JWB57_RS18425	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
JWB57_RS18485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
JWB57_RS18525	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JWB57_RS18555	COG0427	acetyl-CoA hydrolase
JWB57_RS18580	COG0659	secondary active sulfate transmembrane transporter activity
JWB57_RS18585	COG4221	oxidoreductase activity
JWB57_RS18590	COG2873	o-acetylhomoserine
JWB57_RS18595	COG0488	(ABC) transporter
JWB57_RS18660	COG0833	amino acid
JWB57_RS18705	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JWB57_RS18710	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JWB57_RS18725	COG2226	methyltransferase
JWB57_RS18775	COG0070	glutamate synthase
JWB57_RS18775	COG0069	glutamate synthase activity
JWB57_RS18775	COG0067	glutamate synthase
JWB57_RS18780	COG0493	'glutamate synthase
JWB57_RS18790	COG1704	LemA family
JWB57_RS18795	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
JWB57_RS18810	COG3307	-O-antigen
JWB57_RS18830	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JWB57_RS18845	COG0194	GDP metabolic process
JWB57_RS18895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JWB57_RS18915	COG5380	lipid catabolic process
JWB57_RS18920	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JWB57_RS18945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JWB57_RS18950	COG0277	FAD linked oxidase domain protein
JWB57_RS18960	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
JWB57_RS18965	COG2249	NAD(P)H dehydrogenase (quinone) activity
JWB57_RS18980	COG1289	transmembrane transporter activity
JWB57_RS18990	COG0628	permease
JWB57_RS18995	COG1192	Involved in chromosome partitioning
JWB57_RS19025	COG0833	amino acid
JWB57_RS19030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JWB57_RS19035	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JWB57_RS19045	COG1012	belongs to the aldehyde dehydrogenase family
JWB57_RS19085	COG0583	DNA-binding transcription factor activity
JWB57_RS19135	COG0517	IMP dehydrogenase activity
JWB57_RS19140	COG1983	PspC domain protein
JWB57_RS19150	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS19165	COG0408	coproporphyrinogen oxidase activity
JWB57_RS19185	COG0513	Belongs to the DEAD box helicase family
JWB57_RS19195	COG1127	ABC transporter
JWB57_RS19200	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
JWB57_RS19210	COG2854	intermembrane phospholipid transfer
JWB57_RS19220	COG0598	Magnesium transport protein CorA
JWB57_RS19230	COG0494	nUDIX hydrolase
JWB57_RS19235	COG1040	competence protein
JWB57_RS19240	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JWB57_RS19260	COG1946	Acyl-CoA thioesterase
JWB57_RS19265	COG1301	dicarboxylic acid transport
JWB57_RS19280	COG1959	2 iron, 2 sulfur cluster binding
JWB57_RS19285	COG1017	nitric oxide dioxygenase activity
JWB57_RS19285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
JWB57_RS19290	COG0433	COG0433 Predicted ATPase
JWB57_RS19295	COG0626	cystathionine gamma-synthase activity
JWB57_RS19450	COG1960	acyl-CoA dehydrogenase activity
JWB57_RS19455	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
JWB57_RS19485	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
JWB57_RS19490	COG0339	signal peptide processing
JWB57_RS19495	COG0557	exoribonuclease II activity
JWB57_RS19540	COG0179	Fumarylacetoacetate (FAA) hydrolase
JWB57_RS19545	COG2169	Transcriptional regulator
JWB57_RS19550	COG0697	spore germination
JWB57_RS19555	COG1295	ribonuclease BN
JWB57_RS19590	COG1702	phosphate starvation-inducible protein PhoH
JWB57_RS19600	COG0739	heme binding
JWB57_RS19600	COG0741	lytic transglycosylase activity
JWB57_RS19600	COG1196	nuclear chromosome segregation
JWB57_RS19630	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
JWB57_RS19635	COG1183	phosphatidylcholine synthase activity
JWB57_RS19755	COG1525	nuclease
JWB57_RS19820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
JWB57_RS19900	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JWB57_RS19935	COG0741	lytic transglycosylase activity
JWB57_RS19950	COG2826	transposase and inactivated derivatives, IS30 family
JWB57_RS19960	COG2826	transposase and inactivated derivatives, IS30 family
JWB57_RS20010	COG0484	heat shock protein binding
JWB57_RS20200	COG3853	Toxic anion resistance protein (TelA)