locus-tag	class	description
H0529_RS00035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0529_RS00055	COG0823	Involved in the tonB-independent uptake of proteins
H0529_RS00075	COG0824	Thioesterase
H0529_RS00080	COG1473	amidohydrolase
H0529_RS00100	COG0047	phosphoribosylformylglycinamidine synthase activity
H0529_RS00100	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0529_RS00105	COG2814	Major facilitator Superfamily
H0529_RS00115	COG1024	Enoyl-CoA hydratase
H0529_RS00120	COG1056	cytidyltransferase-related domain
H0529_RS00120	COG1051	belongs to the nudix hydrolase family
H0529_RS00130	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0529_RS00145	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0529_RS00160	COG4625	pathogenesis
H0529_RS00165	COG0583	DNA-binding transcription factor activity
H0529_RS00170	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0529_RS00175	COG4208	sulfate ABC transporter
H0529_RS00180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0529_RS00190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0529_RS00195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0529_RS00200	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0529_RS00220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0529_RS00230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H0529_RS00240	COG0681	Belongs to the peptidase S26 family
H0529_RS00255	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0529_RS00265	COG1381	Involved in DNA repair and RecF pathway recombination
H0529_RS00270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0529_RS00280	COG4221	oxidoreductase activity
H0529_RS00310	COG0436	Aminotransferase
H0529_RS00330	COG0556	nucleotide-excision repair
H0529_RS00385	COG2070	2-Nitropropane dioxygenase
H0529_RS00415	COG1215	transferase activity, transferring glycosyl groups
H0529_RS00430	COG0415	Belongs to the DNA photolyase family
H0529_RS00440	COG1252	NADH dehydrogenase
H0529_RS00445	COG1686	Belongs to the peptidase S11 family
H0529_RS00460	COG1187	pseudouridine synthase activity
H0529_RS00480	COG0477	Major facilitator Superfamily
H0529_RS00485	COG0583	DNA-binding transcription factor activity
H0529_RS00490	COG1823	symporter activity
H0529_RS00500	COG0612	Peptidase, M16
H0529_RS00530	COG1203	CRISPR-associated helicase, Cas3
H0529_RS00555	COG0352	thiamine-phosphate diphosphorylase activity
H0529_RS00590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS00605	COG1309	transcriptional regulator
H0529_RS00615	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0529_RS00620	COG0076	glutamate decarboxylase activity
H0529_RS00630	COG1522	sequence-specific DNA binding
H0529_RS00635	COG3961	Belongs to the TPP enzyme family
H0529_RS00640	COG1113	amino acid transport
H0529_RS00645	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0529_RS00650	COG0573	inorganic phosphate transmembrane transporter activity
H0529_RS00660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0529_RS00665	COG0616	signal peptide processing
H0529_RS00700	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0529_RS00705	COG1686	Belongs to the peptidase S11 family
H0529_RS00730	COG0583	DNA-binding transcription factor activity
H0529_RS00735	COG1067	ATP-dependent peptidase activity
H0529_RS00740	COG2211	Major facilitator Superfamily
H0529_RS00760	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0529_RS00780	COG1966	Carbon starvation protein
H0529_RS00785	COG2879	small protein
H0529_RS00795	COG0583	DNA-binding transcription factor activity
H0529_RS00800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0529_RS00815	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS00820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0529_RS00825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0529_RS00825	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H0529_RS00860	COG4948	Mandelate Racemase Muconate Lactonizing
H0529_RS00870	COG1309	transcriptional regulator
H0529_RS00875	COG1309	transcriptional regulator
H0529_RS00890	COG1741	Belongs to the pirin family
H0529_RS00900	COG2964	Protein conserved in bacteria
H0529_RS00915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0529_RS00920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0529_RS00925	COG4605	iron ion homeostasis
H0529_RS00930	COG4604	ABC transporter, ATP-binding protein
H0529_RS00935	COG4607	ABC-type enterochelin transport system periplasmic component
H0529_RS00940	COG4774	siderophore transport
H0529_RS00950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0529_RS00955	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0529_RS00960	COG1535	isochorismatase
H0529_RS00960	COG3433	isochorismatase activity
H0529_RS00975	COG1132	(ABC) transporter
H0529_RS00980	COG1132	(ABC) transporter
H0529_RS00985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0529_RS00990	COG2977	Belongs to the P-Pant transferase superfamily
H0529_RS00995	COG1169	isochorismate synthase
H0529_RS01010	COG3739	integral membrane protein
H0529_RS01030	COG0302	gtp cyclohydrolase
H0529_RS01040	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H0529_RS01050	COG2840	Smr protein MutS2
H0529_RS01070	COG0308	aminopeptidase N
H0529_RS01075	COG0512	Glutamine amidotransferase of anthranilate synthase
H0529_RS01090	COG0174	glutamine synthetase
H0529_RS01100	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0529_RS01135	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0529_RS01140	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0529_RS01145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0529_RS01165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0529_RS01170	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0529_RS01175	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0529_RS01190	COG1960	acyl-CoA dehydrogenase activity
H0529_RS01195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0529_RS01200	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0529_RS01210	COG2223	nitrite transmembrane transporter activity
H0529_RS01220	COG0024	Methionine aminopeptidase
H0529_RS01225	COG0052	Belongs to the universal ribosomal protein uS2 family
H0529_RS01240	COG2207	Transcriptional regulator
H0529_RS01265	COG2951	lytic endotransglycosylase activity
H0529_RS01270	COG0772	Belongs to the SEDS family
H0529_RS01285	COG0842	Transport permease protein
H0529_RS01290	COG1131	(ABC) transporter
H0529_RS01335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS01350	COG4215	(ABC) transporter
H0529_RS01355	COG4160	amino acid transport
H0529_RS01360	COG4598	ABC transporter
H0529_RS01370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0529_RS01375	COG0826	peptidase U32
H0529_RS01380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS01395	COG1720	tRNA m6t6A37 methyltransferase activity
H0529_RS01405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0529_RS01420	COG0642	Histidine kinase
H0529_RS01430	COG0494	nUDIX hydrolase
H0529_RS01440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0529_RS01445	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0529_RS01450	COG3139	Protein of unknown function (DUF1315)
H0529_RS01455	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0529_RS01460	COG1301	dicarboxylic acid transport
H0529_RS01465	COG1960	acyl-CoA dehydrogenase activity
H0529_RS01470	COG2819	hydrolase of the alpha beta superfamily
H0529_RS01480	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0529_RS01490	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0529_RS01510	COG1690	Belongs to the RtcB family
H0529_RS01515	COG1234	tRNA 3'-trailer cleavage
H0529_RS01520	COG4650	regulator
H0529_RS01550	COG2363	Small membrane protein
H0529_RS01570	COG0513	Belongs to the DEAD box helicase family
H0529_RS01580	COG0778	Nitroreductase
H0529_RS01610	COG1286	toxin biosynthetic process
H0529_RS01635	COG4783	chaperone-mediated protein folding
H0529_RS01640	COG1610	YqeY-like protein
H0529_RS01670	COG0515	serine threonine protein kinase
H0529_RS01670	COG2815	serine threonine protein kinase
H0529_RS01695	COG2831	hemolysin activation secretion protein
H0529_RS01700	COG3210	domain, Protein
H0529_RS01700	COG3210	domain, Protein
H0529_RS01785	COG3111	PFAM Bacterial OB fold (BOF) protein
H0529_RS01810	COG3243	poly(R)-hydroxyalkanoic acid synthase
H0529_RS01815	COG0786	glutamate:sodium symporter activity
H0529_RS01825	COG2186	Transcriptional regulator
H0529_RS01875	COG0477	Major facilitator Superfamily
H0529_RS01900	COG2995	paraquat-inducible protein a
H0529_RS01905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0529_RS01905	COG3008	intermembrane lipid transfer
H0529_RS01915	COG2351	hydroxyisourate hydrolase activity
H0529_RS01955	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0529_RS01965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H0529_RS01970	COG0642	Histidine kinase
H0529_RS01975	COG0745	RESPONSE REGULATOR receiver
H0529_RS01995	COG1794	racemase activity, acting on amino acids and derivatives
H0529_RS02025	COG1301	dicarboxylic acid transport
H0529_RS02035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0529_RS02040	COG2011	ABC-type metal ion transport system permease component
H0529_RS02045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0529_RS02050	COG1464	Belongs to the NlpA lipoprotein family
H0529_RS02055	COG0151	Belongs to the GarS family
H0529_RS02060	COG0138	bifunctional purine biosynthesis protein purh
H0529_RS02065	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0529_RS02095	COG2308	Evidence 4 Homologs of previously reported genes of
H0529_RS02105	COG1305	Transglutaminase-like
H0529_RS02115	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0529_RS02120	COG0305	Participates in initiation and elongation during chromosome replication
H0529_RS02145	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0529_RS02155	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0529_RS02160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0529_RS02185	COG1649	PFAM Uncharacterised BCR, COG1649
H0529_RS02185	COG0726	polysaccharide deacetylase
H0529_RS02190	COG1215	transferase activity, transferring glycosyl groups
H0529_RS02195	COG3658	cytochrome
H0529_RS02205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS02220	COG0583	DNA-binding transcription factor activity
H0529_RS02250	COG1960	acyl-CoA dehydrogenase activity
H0529_RS02255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0529_RS02260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS02265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H0529_RS02285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0529_RS02290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0529_RS02300	COG2205	protein histidine kinase activity
H0529_RS02305	COG0745	RESPONSE REGULATOR receiver
H0529_RS02310	COG0174	glutamine synthetase
H0529_RS02330	COG0729	surface antigen
H0529_RS02355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0529_RS02360	COG2814	Major facilitator Superfamily
H0529_RS02515	COG4373	Mu-like prophage FluMu protein gp28
H0529_RS02530	COG4383	Mu-like prophage protein gp29
H0529_RS02535	COG2369	cell adhesion
H0529_RS02655	COG0583	DNA-binding transcription factor activity
H0529_RS02670	COG1187	pseudouridine synthase activity
H0529_RS02690	COG0802	atpase or kinase
H0529_RS02695	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0529_RS02705	COG1923	regulation of RNA biosynthetic process
H0529_RS02710	COG0697	spore germination
H0529_RS02735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0529_RS02740	COG0519	Catalyzes the synthesis of GMP from XMP
H0529_RS02740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0529_RS02745	COG4302	ethanolamine ammonia-lyase activity
H0529_RS02750	COG4303	Ethanolamine ammonia lyase large subunit
H0529_RS02755	COG0531	amino acid
H0529_RS02775	COG1454	alcohol dehydrogenase
H0529_RS02795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0529_RS02815	COG0308	aminopeptidase N
H0529_RS02835	COG1605	Chorismate mutase
H0529_RS02860	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0529_RS02860	COG2885	chlorophyll binding
H0529_RS02880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0529_RS02880	COG2885	chlorophyll binding
H0529_RS02915	COG1538	Outer membrane efflux protein
H0529_RS02945	COG1234	tRNA 3'-trailer cleavage
H0529_RS02950	COG2271	Major facilitator Superfamily
H0529_RS02960	COG3971	2-oxopent-4-enoate hydratase activity
H0529_RS02965	COG4569	acetaldehyde dehydrogenase (acetylating) activity
H0529_RS02985	COG0583	DNA-binding transcription factor activity
H0529_RS02990	COG4638	Rieske (2fe-2S)
H0529_RS02995	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0529_RS03005	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS03010	COG3384	dioxygenase
H0529_RS03015	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0529_RS03020	COG2814	Major facilitator Superfamily
H0529_RS03025	COG2814	Major facilitator Superfamily
H0529_RS03030	COG0583	DNA-binding transcription factor activity
H0529_RS03070	COG0668	transmembrane transport
H0529_RS03100	COG4773	Receptor
H0529_RS03120	COG0488	(ABC) transporter
H0529_RS03125	COG0589	response to stress
H0529_RS03150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H0529_RS03160	COG3135	benzoate transporter
H0529_RS03165	COG1522	sequence-specific DNA binding
H0529_RS03175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0529_RS03180	COG0583	DNA-binding transcription factor activity
H0529_RS03190	COG0183	Belongs to the thiolase family
H0529_RS03200	COG2030	dehydratase
H0529_RS03205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0529_RS03230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0529_RS03245	COG0824	Thioesterase
H0529_RS03250	COG1454	alcohol dehydrogenase
H0529_RS03260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0529_RS03280	COG0069	glutamate synthase activity
H0529_RS03300	COG2814	Major facilitator Superfamily
H0529_RS03315	COG0511	ligase activity, forming carbon-carbon bonds
H0529_RS03335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0529_RS03335	COG1116	anion transmembrane transporter activity
H0529_RS03340	COG0745	RESPONSE REGULATOR receiver
H0529_RS03350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0529_RS03350	COG2146	nitrite reductase [NAD(P)H] activity
H0529_RS03355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0529_RS03360	COG0243	molybdopterin cofactor binding
H0529_RS03370	COG0243	molybdopterin cofactor binding
H0529_RS03375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0529_RS03390	COG0315	cyclic pyranopterin monophosphate synthase activity
H0529_RS03390	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0529_RS03405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS03410	COG0697	spore germination
H0529_RS03430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0529_RS03435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0529_RS03490	COG2204	response regulator
H0529_RS03495	COG3852	Histidine kinase
H0529_RS03520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0529_RS03525	COG0575	Belongs to the CDS family
H0529_RS03560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0529_RS03575	COG2137	regulation of response to DNA damage stimulus
H0529_RS03585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0529_RS03590	COG1011	Hydrolase
H0529_RS03615	COG1522	sequence-specific DNA binding
H0529_RS03625	COG1113	amino acid transport
H0529_RS03640	COG0659	secondary active sulfate transmembrane transporter activity
H0529_RS03660	COG5001	Diguanylate cyclase
H0529_RS03660	COG3300	MHYT domain
H0529_RS03675	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H0529_RS03675	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0529_RS03675	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H0529_RS03680	COG1105	Belongs to the carbohydrate kinase PfkB family
H0529_RS03685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0529_RS03685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0529_RS03715	COG0024	Methionine aminopeptidase
H0529_RS03720	COG0583	DNA-binding transcription factor activity
H0529_RS03730	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0529_RS03735	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0529_RS03740	COG0516	GMP reductase activity
H0529_RS03740	COG0517	IMP dehydrogenase activity
H0529_RS03765	COG0552	protein localization to endoplasmic reticulum
H0529_RS03775	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H0529_RS03785	COG4890	Cyd operon protein YbgT
H0529_RS03790	COG1294	oxidase, subunit
H0529_RS03805	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0529_RS03815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0529_RS03820	COG4774	siderophore transport
H0529_RS03835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0529_RS03840	COG0569	domain protein
H0529_RS03845	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0529_RS03875	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0529_RS03880	COG0542	response to heat
H0529_RS03905	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0529_RS03905	COG1902	pentaerythritol trinitrate reductase activity
H0529_RS03950	COG2323	membrane
H0529_RS03955	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0529_RS03965	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0529_RS03970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0529_RS03975	COG0183	Belongs to the thiolase family
H0529_RS03980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0529_RS03985	COG0596	Alpha beta hydrolase
H0529_RS03990	COG2271	Major facilitator Superfamily
H0529_RS03995	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0529_RS04000	COG3485	protocatechuate 3,4-dioxygenase
H0529_RS04005	COG3485	protocatechuate 3,4-dioxygenase
H0529_RS04010	COG0710	3-dehydroquinate dehydratase activity
H0529_RS04015	COG3420	alginic acid biosynthetic process
H0529_RS04020	COG3659	wide pore channel activity
H0529_RS04025	COG4993	Dehydrogenase
H0529_RS04035	COG2391	methyltransferase activity
H0529_RS04050	COG1414	Transcriptional regulator
H0529_RS04055	COG0583	DNA-binding transcription factor activity
H0529_RS04060	COG1960	acyl-CoA dehydrogenase activity
H0529_RS04085	COG2814	Major facilitator Superfamily
H0529_RS04095	COG0154	amidase activity
H0529_RS04115	COG4638	Rieske (2fe-2S)
H0529_RS04125	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS04135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS04145	COG3733	amine oxidase
H0529_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS04160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0529_RS04165	COG0183	Belongs to the thiolase family
H0529_RS04170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0529_RS04175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0529_RS04185	COG4829	muconolactone delta-isomerase
H0529_RS04190	COG4948	Mandelate Racemase Muconate Lactonizing
H0529_RS04195	COG0583	DNA-binding transcription factor activity
H0529_RS04205	COG2186	Transcriptional regulator
H0529_RS04225	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS04230	COG3231	kanamycin kinase activity
H0529_RS04245	COG1960	acyl-CoA dehydrogenase activity
H0529_RS04250	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS04255	COG3829	transcription factor binding
H0529_RS04265	COG3162	membrane
H0529_RS04280	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS04315	COG1846	Transcriptional regulator
H0529_RS04330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H0529_RS04360	COG1309	transcriptional regulator
H0529_RS04370	COG1335	isochorismatase
H0529_RS04375	COG0583	DNA-binding transcription factor activity
H0529_RS04385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0529_RS04385	COG0475	glutathione-regulated potassium exporter activity
H0529_RS04395	COG1473	amidohydrolase
H0529_RS04455	COG2188	Transcriptional regulator
H0529_RS04470	COG0583	DNA-binding transcription factor activity
H0529_RS04495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS04510	COG2271	Major facilitator Superfamily
H0529_RS04520	COG1566	PFAM secretion protein HlyD family protein
H0529_RS04535	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS04540	COG0129	dihydroxy-acid dehydratase activity
H0529_RS04550	COG0583	DNA-binding transcription factor activity
H0529_RS04555	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0529_RS04565	COG2084	Dehydrogenase
H0529_RS04570	COG2207	Transcriptional regulator
H0529_RS04585	COG1064	alcohol dehydrogenase
H0529_RS04595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0529_RS04600	COG1120	ATPase activity
H0529_RS04620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0529_RS04670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0529_RS04710	COG1073	alpha beta
H0529_RS04730	COG2205	protein histidine kinase activity
H0529_RS04735	COG0745	RESPONSE REGULATOR receiver
H0529_RS04740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS04745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0529_RS04760	COG0402	S-adenosylhomocysteine deaminase activity
H0529_RS04770	COG2814	Major facilitator Superfamily
H0529_RS04780	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0529_RS04795	COG1024	Enoyl-CoA hydratase
H0529_RS04935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS04940	COG4771	TonB-dependent receptor
H0529_RS04970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS04975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0529_RS04980	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0529_RS04985	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0529_RS05000	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
H0529_RS05015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS05035	COG1132	(ABC) transporter
H0529_RS05040	COG1132	(ABC) transporter
H0529_RS05060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0529_RS05065	COG0601	transmembrane transport
H0529_RS05070	COG0747	negative chemotaxis
H0529_RS05095	COG3539	Fimbrial protein
H0529_RS05125	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0529_RS05140	COG0753	catalase activity
H0529_RS05155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0529_RS05220	COG1535	isochorismatase
H0529_RS05220	COG3433	isochorismatase activity
H0529_RS05225	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS05230	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H0529_RS05235	COG4149	molybdate abc transporter
H0529_RS05240	COG0725	ABC transporter, periplasmic molybdate-binding protein
H0529_RS05250	COG4638	Rieske (2fe-2S)
H0529_RS05255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0529_RS05260	COG0543	2 iron, 2 sulfur cluster binding
H0529_RS05260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS05275	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS05285	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS05300	COG2207	Transcriptional regulator
H0529_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS05310	COG2610	gluconate transmembrane transporter activity
H0529_RS05320	COG2826	transposase and inactivated derivatives, IS30 family
H0529_RS05345	COG0583	DNA-binding transcription factor activity
H0529_RS05360	COG2031	fatty acid transporter
H0529_RS05365	COG0183	Belongs to the thiolase family
H0529_RS05370	COG0583	DNA-binding transcription factor activity
H0529_RS05375	COG0583	DNA-binding transcription factor activity
H0529_RS05390	COG1027	Aspartate ammonia-lyase
H0529_RS05400	COG0477	Major facilitator Superfamily
H0529_RS05420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0529_RS05425	COG4521	taurine ABC transporter
H0529_RS05440	COG2188	Transcriptional regulator
H0529_RS05450	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0529_RS05455	COG1733	regulation of RNA biosynthetic process
H0529_RS05460	COG2207	Transcriptional regulator
H0529_RS05460	COG3708	Transcriptional regulator
H0529_RS05475	COG0730	response to heat
H0529_RS05485	COG3453	Protein conserved in bacteria
H0529_RS05485	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0529_RS05495	COG3781	membrane
H0529_RS05500	COG1063	alcohol dehydrogenase
H0529_RS05510	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0529_RS05515	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0529_RS05520	COG0022	dehydrogenase e1 component
H0529_RS05525	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0529_RS05530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0529_RS05545	COG3706	GGDEF domain
H0529_RS05560	COG0133	tryptophan synthase activity
H0529_RS05570	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0529_RS05605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0529_RS05630	COG2226	methyltransferase
H0529_RS05685	COG0842	Transport permease protein
H0529_RS05690	COG0842	Transport permease protein
H0529_RS05695	COG1131	(ABC) transporter
H0529_RS05710	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0529_RS05715	COG4773	Receptor
H0529_RS05735	COG0730	response to heat
H0529_RS05740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0529_RS05755	COG0406	alpha-ribazole phosphatase activity
H0529_RS05760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H0529_RS05775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0529_RS05805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0529_RS05815	COG4264	IucA IucC family
H0529_RS05820	COG4264	IucA IucC family
H0529_RS05825	COG2814	Major facilitator Superfamily
H0529_RS05840	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0529_RS05855	COG1960	acyl-CoA dehydrogenase activity
H0529_RS05860	COG1960	acyl-CoA dehydrogenase activity
H0529_RS05865	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0529_RS05870	COG2207	Transcriptional regulator
H0529_RS05875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0529_RS05880	COG0776	regulation of translation
H0529_RS05905	COG0822	iron-sulfur transferase activity
H0529_RS05910	COG0316	Belongs to the HesB IscA family
H0529_RS05940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0529_RS05960	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0529_RS05965	COG0702	epimerase
H0529_RS06000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0529_RS06010	COG0339	signal peptide processing
H0529_RS06060	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0529_RS06130	COG0739	heme binding
H0529_RS06130	COG0741	lytic transglycosylase activity
H0529_RS06130	COG1196	nuclear chromosome segregation
H0529_RS06295	COG0305	Participates in initiation and elongation during chromosome replication
H0529_RS06310	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0529_RS06360	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0529_RS06390	COG0776	regulation of translation
H0529_RS06455	COG0084	hydrolase, TatD family'
H0529_RS06475	COG1663	tetraacyldisaccharide 4'-kinase activity
H0529_RS06480	COG1132	(ABC) transporter
H0529_RS06490	COG0811	peptide transport
H0529_RS06495	COG1475	DNA binding
H0529_RS06500	COG1192	Involved in chromosome partitioning
H0529_RS06510	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0529_RS06525	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0529_RS06530	COG0191	fructose-bisphosphate aldolase activity
H0529_RS06550	COG0424	maF-like protein
H0529_RS06555	COG2850	peptidyl-arginine hydroxylation
H0529_RS06565	COG0640	Transcriptional regulator
H0529_RS06575	COG3619	membrane
H0529_RS06580	COG3122	Protein conserved in bacteria
H0529_RS06585	COG1132	(ABC) transporter
H0529_RS06605	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0529_RS06610	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0529_RS06620	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0529_RS06620	COG0506	proline dehydrogenase activity
H0529_RS06620	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0529_RS06625	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H0529_RS06640	COG3698	Phosphodiester glycosidase
H0529_RS06650	COG2353	YceI-like domain
H0529_RS06660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0529_RS06715	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0529_RS06715	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0529_RS06740	COG3539	Fimbrial protein
H0529_RS06745	COG3121	Chaperone
H0529_RS06770	COG0697	spore germination
H0529_RS06780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0529_RS06790	COG0583	DNA-binding transcription factor activity
H0529_RS06810	COG1309	transcriptional regulator
H0529_RS06825	COG1522	sequence-specific DNA binding
H0529_RS06835	COG1126	abc transporter atp-binding protein
H0529_RS06840	COG0765	amino acid transport
H0529_RS06845	COG0765	amino acid transport
H0529_RS06875	COG1464	Belongs to the NlpA lipoprotein family
H0529_RS06885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0529_RS06890	COG2011	ABC-type metal ion transport system permease component
H0529_RS06895	COG0012	GTP binding
H0529_RS06920	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0529_RS06960	COG0386	Belongs to the glutathione peroxidase family
H0529_RS06970	COG0436	Aminotransferase
H0529_RS06975	COG1301	dicarboxylic acid transport
H0529_RS07010	COG3634	alkyl hydroperoxide reductase activity
H0529_RS07025	COG0583	DNA-binding transcription factor activity
H0529_RS07030	COG0798	PFAM Bile acid sodium symporter
H0529_RS07035	COG0640	Transcriptional regulator
H0529_RS07060	COG0583	DNA-binding transcription factor activity
H0529_RS07070	COG1953	Uracil, thiamine, allantoin
H0529_RS07080	COG2175	clavaminate synthase activity
H0529_RS07085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0529_RS07090	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H0529_RS07095	COG4521	taurine ABC transporter
H0529_RS07105	COG0477	Major facilitator Superfamily
H0529_RS07125	COG1271	oxidase subunit
H0529_RS07130	COG1294	oxidase, subunit
H0529_RS07140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS07160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0529_RS07180	COG3052	prosthetic group binding
H0529_RS07185	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H0529_RS07195	COG0300	oxidoreductase activity
H0529_RS07215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS07220	COG1346	cytolysis
H0529_RS07230	COG0583	DNA-binding transcription factor activity
H0529_RS07235	COG0625	glutathione transferase activity
H0529_RS07240	COG0625	glutathione transferase activity
H0529_RS07245	COG0583	DNA-binding transcription factor activity
H0529_RS07260	COG1045	serine acetyltransferase
H0529_RS07265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0529_RS07270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0529_RS07275	COG1280	lysine exporter protein (LysE YggA)
H0529_RS07290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0529_RS07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0529_RS07300	COG1126	abc transporter atp-binding protein
H0529_RS07305	COG0765	amino acid transport
H0529_RS07310	COG0765	amino acid transport
H0529_RS07330	COG0784	Response regulator, receiver
H0529_RS07330	COG2205	protein histidine kinase activity
H0529_RS07350	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0529_RS07370	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS07420	COG0583	DNA-binding transcription factor activity
H0529_RS07440	COG0318	PFAM AMP-dependent synthetase and ligase
H0529_RS07445	COG1309	transcriptional regulator
H0529_RS07450	COG1960	acyl-CoA dehydrogenase activity
H0529_RS07455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0529_RS07460	COG1024	Enoyl-CoA hydratase
H0529_RS07465	COG4770	biotin carboxylase activity
H0529_RS07475	COG0583	DNA-binding transcription factor activity
H0529_RS07490	COG1960	acyl-CoA dehydrogenase activity
H0529_RS07500	COG2814	Major facilitator Superfamily
H0529_RS07510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0529_RS07515	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0529_RS07520	COG2814	Major facilitator Superfamily
H0529_RS07525	COG1960	acyl-CoA dehydrogenase activity
H0529_RS07530	COG1024	Enoyl-CoA hydratase
H0529_RS07535	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS07540	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0529_RS07545	COG0183	Belongs to the thiolase family
H0529_RS07555	COG2814	Major facilitator Superfamily
H0529_RS07565	COG1024	Enoyl-CoA hydratase
H0529_RS07580	COG1960	acyl-CoA dehydrogenase activity
H0529_RS07585	COG2814	Major facilitator Superfamily
H0529_RS07590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0529_RS07595	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0529_RS07610	COG3842	ATPase activity
H0529_RS07615	COG1840	ABC-type Fe3 transport system, periplasmic component
H0529_RS07625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS07630	COG1414	Transcriptional regulator
H0529_RS07640	COG0583	DNA-binding transcription factor activity
H0529_RS07645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0529_RS07650	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS07660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0529_RS07670	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS07675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS07680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS07685	COG2267	carboxylic ester hydrolase activity
H0529_RS07705	COG3038	cytochrome b561
H0529_RS07710	COG0753	catalase activity
H0529_RS07730	COG2050	protein possibly involved in aromatic compounds catabolism
H0529_RS07740	COG3327	negative regulation of DNA-templated transcription, initiation
H0529_RS07745	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H0529_RS07750	COG0183	Belongs to the thiolase family
H0529_RS07755	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0529_RS07760	COG1024	Enoyl-CoA hydratase
H0529_RS07765	COG1024	Enoyl-CoA hydratase
H0529_RS07770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS07775	COG2151	metal-sulfur cluster biosynthetic enzyme
H0529_RS07780	COG3396	Phenylacetate-CoA oxygenase
H0529_RS07785	COG3460	Phenylacetate-CoA oxygenase
H0529_RS07790	COG3396	Phenylacetate-CoA oxygenase
H0529_RS07795	COG2030	dehydratase
H0529_RS07795	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS07800	COG1760	l-serine dehydratase
H0529_RS07805	COG0531	amino acid
H0529_RS07810	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS07835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0529_RS07855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0529_RS07865	COG0789	Transcriptional regulator
H0529_RS07875	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0529_RS07890	COG2807	transmembrane transport
H0529_RS07895	COG0590	tRNA wobble adenosine to inosine editing
H0529_RS08050	COG1116	anion transmembrane transporter activity
H0529_RS08055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0529_RS08065	COG0864	Transcriptional regulator
H0529_RS08075	COG1733	regulation of RNA biosynthetic process
H0529_RS08080	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0529_RS08085	COG0439	Biotin carboxylase
H0529_RS08100	COG1063	alcohol dehydrogenase
H0529_RS08110	COG1309	transcriptional regulator
H0529_RS08120	COG3210	domain, Protein
H0529_RS08125	COG2831	hemolysin activation secretion protein
H0529_RS08130	COG0038	chloride channel
H0529_RS08135	COG4770	biotin carboxylase activity
H0529_RS08155	COG1914	H( )-stimulated, divalent metal cation uptake system
H0529_RS08160	COG0583	DNA-binding transcription factor activity
H0529_RS08180	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0529_RS08200	COG2814	Major facilitator Superfamily
H0529_RS08215	COG1560	Kdo2-lipid A biosynthetic process
H0529_RS08225	COG5006	permease, DMT superfamily
H0529_RS08230	COG1522	sequence-specific DNA binding
H0529_RS08245	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0529_RS08255	COG4122	O-methyltransferase activity
H0529_RS08285	COG1538	Outer membrane efflux protein
H0529_RS08295	COG1137	ATPase activity
H0529_RS08300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0529_RS08310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0529_RS08315	COG0517	IMP dehydrogenase activity
H0529_RS08315	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H0529_RS08380	COG2814	Major facilitator Superfamily
H0529_RS08415	COG1278	Cold shock
H0529_RS08420	COG1280	lysine exporter protein (LysE YggA)
H0529_RS08450	COG1570	exodeoxyribonuclease VII activity
H0529_RS08535	COG2871	sodium ion transport
H0529_RS08545	COG0583	DNA-binding transcription factor activity
H0529_RS08555	COG4638	Rieske (2fe-2S)
H0529_RS08560	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0529_RS08565	COG0543	2 iron, 2 sulfur cluster binding
H0529_RS08565	COG0633	Ferredoxin
H0529_RS08570	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS08575	COG3135	benzoate transporter
H0529_RS08580	COG2814	Major facilitator Superfamily
H0529_RS08595	COG1643	Atp-dependent helicase
H0529_RS08600	COG0450	alkyl hydroperoxide reductase
H0529_RS08610	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0529_RS08620	COG3634	alkyl hydroperoxide reductase activity
H0529_RS08640	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0529_RS08645	COG0625	glutathione transferase activity
H0529_RS08655	COG2885	chlorophyll binding
H0529_RS08690	COG0542	response to heat
H0529_RS08705	COG1765	OsmC-like protein
H0529_RS08720	COG0667	Aldo Keto reductase
H0529_RS08735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0529_RS08745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0529_RS08755	COG0582	viral genome integration into host DNA
H0529_RS08760	COG2194	sulfuric ester hydrolase activity
H0529_RS08875	COG3566	protein conserved in bacteria
H0529_RS08890	COG3567	Phage-associated protein, HI1409 family
H0529_RS08895	COG5410	chromosome segregation
H0529_RS09085	COG0527	aspartate kinase activity
H0529_RS09095	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0529_RS09105	COG3038	cytochrome b561
H0529_RS09110	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0529_RS09115	COG2252	PERMEase
H0529_RS09125	COG2072	flavoprotein involved in K transport
H0529_RS09140	COG1741	Belongs to the pirin family
H0529_RS09145	COG1309	transcriptional regulator
H0529_RS09155	COG0300	oxidoreductase activity
H0529_RS09160	COG2072	flavoprotein involved in K transport
H0529_RS09165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H0529_RS09170	COG0583	DNA-binding transcription factor activity
H0529_RS09185	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0529_RS09190	COG2207	Transcriptional regulator
H0529_RS09230	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0529_RS09245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS09260	COG2814	Major facilitator Superfamily
H0529_RS09265	COG1024	Enoyl-CoA hydratase
H0529_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS09280	COG1960	acyl-CoA dehydrogenase activity
H0529_RS09305	COG2186	Transcriptional regulator
H0529_RS09310	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS09320	COG4948	Mandelate Racemase Muconate Lactonizing
H0529_RS09325	COG2271	Major facilitator Superfamily
H0529_RS09330	COG2721	sulfolactate sulfo-lyase activity
H0529_RS09335	COG0697	spore germination
H0529_RS09350	COG1113	amino acid transport
H0529_RS09370	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS09390	COG0531	amino acid
H0529_RS09400	COG1113	amino acid transport
H0529_RS09435	COG0183	Belongs to the thiolase family
H0529_RS09440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0529_RS09445	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0529_RS09460	COG3485	protocatechuate 3,4-dioxygenase
H0529_RS09465	COG1454	alcohol dehydrogenase
H0529_RS09470	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS09490	COG2814	Major facilitator Superfamily
H0529_RS09495	COG0583	DNA-binding transcription factor activity
H0529_RS09505	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0529_RS09540	COG2059	Chromate
H0529_RS09550	COG1230	cation diffusion facilitator family transporter
H0529_RS09565	COG2814	Major facilitator Superfamily
H0529_RS09675	COG0582	viral genome integration into host DNA
H0529_RS09680	COG0582	viral genome integration into host DNA
H0529_RS09690	COG2801	Transposase and inactivated derivatives
H0529_RS09695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H0529_RS09725	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H0529_RS09735	COG2184	nucleotidyltransferase activity
H0529_RS09795	COG0789	Transcriptional regulator
H0529_RS09875	COG1902	pentaerythritol trinitrate reductase activity
H0529_RS09875	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0529_RS09885	COG4251	negative regulation of phosphorylation
H0529_RS09885	COG2203	Gaf domain
H0529_RS09885	COG3706	GGDEF domain
H0529_RS09885	COG5001	Diguanylate cyclase
H0529_RS09895	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0529_RS09915	COG4172	Belongs to the ABC transporter superfamily
H0529_RS09920	COG4239	(ABC) transporter, permease
H0529_RS09925	COG4174	ABC transporter (Permease)
H0529_RS09935	COG1388	LysM domain
H0529_RS09935	COG1388	LysM domain
H0529_RS09935	COG0741	lytic transglycosylase activity
H0529_RS09935	COG0741	lytic transglycosylase activity
H0529_RS09940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0529_RS09980	COG0583	DNA-binding transcription factor activity
H0529_RS09985	COG1279	arginine transmembrane transporter activity
H0529_RS10005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS10010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS10015	COG0006	proline dipeptidase activity
H0529_RS10060	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0529_RS10080	COG3384	dioxygenase
H0529_RS10090	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0529_RS10095	COG2878	Part of a membrane complex involved in electron transport
H0529_RS10100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0529_RS10125	COG0768	penicillin binding
H0529_RS10130	COG0742	ribosomal rna small subunit methyltransferase
H0529_RS10145	COG0830	nickel cation binding
H0529_RS10155	COG0804	urea catabolic process
H0529_RS10195	COG1253	flavin adenine dinucleotide binding
H0529_RS10200	COG2851	Citrate transporter
H0529_RS10250	COG1773	rubredoxin
H0529_RS10255	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0529_RS10265	COG0583	DNA-binding transcription factor activity
H0529_RS10295	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0529_RS10300	COG4181	ATPase activity
H0529_RS10345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0529_RS10365	COG0306	phosphate transporter
H0529_RS10375	COG3958	Transketolase
H0529_RS10380	COG3959	Transketolase, thiamine diphosphate binding domain
H0529_RS10385	COG2271	Major facilitator Superfamily
H0529_RS10390	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS10395	COG0583	DNA-binding transcription factor activity
H0529_RS10410	COG2223	nitrite transmembrane transporter activity
H0529_RS10415	COG2207	Transcriptional regulator
H0529_RS10420	COG2066	Belongs to the glutaminase family
H0529_RS10425	COG0242	peptide deformylase activity
H0529_RS10430	COG0477	Major facilitator Superfamily
H0529_RS10435	COG2826	transposase and inactivated derivatives, IS30 family
H0529_RS10445	COG0028	Belongs to the TPP enzyme family
H0529_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS10465	COG2267	carboxylic ester hydrolase activity
H0529_RS10475	COG2271	Major facilitator Superfamily
H0529_RS10510	COG1414	Transcriptional regulator
H0529_RS10525	COG1024	Enoyl-CoA hydratase
H0529_RS10535	COG1215	transferase activity, transferring glycosyl groups
H0529_RS10540	COG1649	PFAM Uncharacterised BCR, COG1649
H0529_RS10540	COG0726	polysaccharide deacetylase
H0529_RS10550	COG4681	YaeQ
H0529_RS10560	COG0523	cobalamin synthesis protein
H0529_RS10570	COG1607	acyl-coa hydrolase
H0529_RS10580	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0529_RS10585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0529_RS10590	COG1309	transcriptional regulator
H0529_RS10615	COG2040	homocysteine
H0529_RS10620	COG0531	amino acid
H0529_RS10650	COG0582	viral genome integration into host DNA
H0529_RS10670	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0529_RS10740	COG0592	DNA-directed DNA polymerase activity
H0529_RS10775	COG2026	Addiction module toxin, RelE StbE family
H0529_RS10960	COG1484	DNA-dependent DNA replication
H0529_RS11050	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0529_RS11120	COG0405	Gamma-glutamyltransferase
H0529_RS11125	COG2814	Major facilitator Superfamily
H0529_RS11130	COG1566	PFAM secretion protein HlyD family protein
H0529_RS11135	COG2050	protein possibly involved in aromatic compounds catabolism
H0529_RS11150	COG1090	epimerase
H0529_RS11170	COG0420	3'-5' exonuclease activity
H0529_RS11195	COG0735	belongs to the Fur family
H0529_RS11200	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0529_RS11220	COG0121	glutamine amidotransferase
H0529_RS11235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0529_RS11245	COG0210	DNA helicase
H0529_RS11250	COG2885	chlorophyll binding
H0529_RS11255	COG0204	Acyl-transferase
H0529_RS11270	COG2894	cell division
H0529_RS11285	COG1280	lysine exporter protein (LysE YggA)
H0529_RS11290	COG1674	ftsk spoiiie
H0529_RS11290	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0529_RS11295	COG0492	ferredoxin-NADP+ reductase activity
H0529_RS11300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0529_RS11310	COG0456	acetyltransferase
H0529_RS11355	COG1981	membrane
H0529_RS11370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0529_RS11370	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0529_RS11390	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS11400	COG0657	acetylesterase activity
H0529_RS11410	COG0473	3-isopropylmalate dehydrogenase activity
H0529_RS11415	COG0583	DNA-binding transcription factor activity
H0529_RS11435	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0529_RS11445	COG0582	viral genome integration into host DNA
H0529_RS11550	COG3646	Phage regulatory protein
H0529_RS11800	COG0564	pseudouridine synthase activity
H0529_RS11810	COG0358	DNA primase activity
H0529_RS11825	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0529_RS11855	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0529_RS11885	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0529_RS11895	COG0351	phosphomethylpyrimidine kinase
H0529_RS11895	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0529_RS11895	COG0352	thiamine-phosphate diphosphorylase activity
H0529_RS11900	COG1652	LysM domain
H0529_RS11925	COG1399	metal-binding, possibly nucleic acid-binding protein
H0529_RS11930	COG3101	peptidyl-lysine hydroxylation
H0529_RS11935	COG0009	L-threonylcarbamoyladenylate synthase
H0529_RS11940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H0529_RS11945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0529_RS11960	COG4106	trans-aconitate 2-methyltransferase activity
H0529_RS11975	COG2226	methyltransferase
H0529_RS11975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0529_RS11975	COG0596	Alpha beta hydrolase
H0529_RS11980	COG1877	trehalose-phosphatase activity
H0529_RS11985	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0529_RS11990	COG2223	nitrite transmembrane transporter activity
H0529_RS12010	COG1196	nuclear chromosome segregation
H0529_RS12020	COG0730	response to heat
H0529_RS12035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0529_RS12045	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0529_RS12095	COG0489	protein tyrosine kinase activity
H0529_RS12105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0529_RS12105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0529_RS12135	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0529_RS12140	COG2081	HI0933 family
H0529_RS12150	COG0668	transmembrane transport
H0529_RS12170	COG0583	DNA-binding transcription factor activity
H0529_RS12190	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0529_RS12195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0529_RS12225	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0529_RS12265	COG0745	RESPONSE REGULATOR receiver
H0529_RS12285	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0529_RS12295	COG1301	dicarboxylic acid transport
H0529_RS12300	COG0583	DNA-binding transcription factor activity
H0529_RS12310	COG0697	spore germination
H0529_RS12345	COG2271	Major facilitator Superfamily
H0529_RS12360	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS12395	COG3621	Patatin-like phospholipase
H0529_RS12455	COG0384	phenazine biosynthesis protein PhzF
H0529_RS12480	COG5290	Psort location Cytoplasmic, score
H0529_RS12490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS12535	COG0583	DNA-binding transcription factor activity
H0529_RS12550	COG0583	DNA-binding transcription factor activity
H0529_RS12555	COG1053	succinate dehydrogenase
H0529_RS12565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0529_RS12570	COG2814	Major facilitator Superfamily
H0529_RS12575	COG1960	acyl-CoA dehydrogenase activity
H0529_RS12580	COG0583	DNA-binding transcription factor activity
H0529_RS12585	COG1063	alcohol dehydrogenase
H0529_RS12615	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0529_RS12620	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0529_RS12625	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0529_RS12645	COG2132	Multicopper oxidase
H0529_RS12655	COG0561	phosphatase activity
H0529_RS12660	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0529_RS12685	COG1214	PFAM Peptidase M22, glycoprotease
H0529_RS12730	COG1134	teichoic acid transport
H0529_RS12730	COG1388	LysM domain
H0529_RS12735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0529_RS12745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0529_RS12750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0529_RS12755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0529_RS12815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0529_RS12825	COG1846	Transcriptional regulator
H0529_RS12830	COG1764	response to oxidative stress
H0529_RS12870	COG0037	tRNA processing
H0529_RS12880	COG0248	Ppx GppA phosphatase
H0529_RS12910	COG0072	phenylalanine-tRNA ligase activity
H0529_RS12950	COG1238	metal cluster binding
H0529_RS12955	COG0625	glutathione transferase activity
H0529_RS12970	COG0318	PFAM AMP-dependent synthetase and ligase
H0529_RS12975	COG3028	Belongs to the UPF0307 family
H0529_RS12980	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0529_RS13000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0529_RS13005	COG0617	tRNA 3'-terminal CCA addition
H0529_RS13010	COG1555	photosystem II stabilization
H0529_RS13015	COG3956	TIGRFAM MazG family protein
H0529_RS13025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0529_RS13045	COG2205	protein histidine kinase activity
H0529_RS13045	COG5002	protein histidine kinase activity
H0529_RS13045	COG0784	Response regulator, receiver
H0529_RS13050	COG1024	Enoyl-CoA hydratase
H0529_RS13055	COG2084	Dehydrogenase
H0529_RS13060	COG3622	Belongs to the hyi family
H0529_RS13090	COG0697	spore germination
H0529_RS13100	COG2814	Major facilitator Superfamily
H0529_RS13125	COG2072	flavoprotein involved in K transport
H0529_RS13130	COG0492	ferredoxin-NADP+ reductase activity
H0529_RS13135	COG0431	NADPH-dependent FMN reductase
H0529_RS13140	COG0798	PFAM Bile acid sodium symporter
H0529_RS13150	COG0640	Transcriptional regulator
H0529_RS13185	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0529_RS13210	COG2132	Multicopper oxidase
H0529_RS13225	COG2205	protein histidine kinase activity
H0529_RS13310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0529_RS13320	COG0583	DNA-binding transcription factor activity
H0529_RS13330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0529_RS13340	COG0084	hydrolase, TatD family'
H0529_RS13355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H0529_RS13380	COG2130	NADP-dependent
H0529_RS13385	COG1309	transcriptional regulator
H0529_RS13405	COG1979	alcohol dehydrogenase
H0529_RS13415	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H0529_RS13435	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0529_RS13440	COG0583	DNA-binding transcription factor activity
H0529_RS13445	COG4221	oxidoreductase activity
H0529_RS13635	COG0440	acetolactate synthase activity
H0529_RS13640	COG0028	Belongs to the TPP enzyme family
H0529_RS13665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS13670	COG0577	efflux transmembrane transporter activity
H0529_RS13670	COG1136	(ABC) transporter
H0529_RS13675	COG1538	Outer membrane efflux protein
H0529_RS13690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0529_RS13695	COG1162	GTPase activity
H0529_RS13705	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0529_RS13745	COG1426	Protein conserved in bacteria
H0529_RS13780	COG0793	Belongs to the peptidase S41A family
H0529_RS13795	COG2267	carboxylic ester hydrolase activity
H0529_RS13805	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS13810	COG3265	gluconokinase activity
H0529_RS13820	COG0800	Aldolase
H0529_RS13830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0529_RS13835	COG0857	belongs to the CobB CobQ family
H0529_RS13835	COG0280	phosphate acetyltransferase
H0529_RS13840	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0529_RS13840	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0529_RS13860	COG0740	serine-type endopeptidase activity
H0529_RS13870	COG4774	siderophore transport
H0529_RS13880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0529_RS13890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0529_RS13890	COG2813	Specifically methylates the guanine in position
H0529_RS14040	COG0788	formyltetrahydrofolate deformylase activity
H0529_RS14065	COG4651	solute:proton antiporter activity
H0529_RS14065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0529_RS14085	COG0724	RNA recognition motif
H0529_RS14090	COG0210	DNA helicase
H0529_RS14115	COG1733	regulation of RNA biosynthetic process
H0529_RS14125	COG2900	Belongs to the SlyX family
H0529_RS14130	COG0488	(ABC) transporter
H0529_RS14140	COG1280	lysine exporter protein (LysE YggA)
H0529_RS14145	COG1560	Kdo2-lipid A biosynthetic process
H0529_RS14155	COG1301	dicarboxylic acid transport
H0529_RS14210	COG0473	3-isopropylmalate dehydrogenase activity
H0529_RS14265	COG0583	DNA-binding transcription factor activity
H0529_RS14275	COG0625	glutathione transferase activity
H0529_RS14280	COG2378	regulation of single-species biofilm formation
H0529_RS14285	COG0546	phosphoglycolate phosphatase activity
H0529_RS14295	COG1530	ribonuclease E activity
H0529_RS14300	COG0318	PFAM AMP-dependent synthetase and ligase
H0529_RS14315	COG0583	DNA-binding transcription factor activity
H0529_RS14320	COG4221	oxidoreductase activity
H0529_RS14325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0529_RS14335	COG0534	Mate efflux family protein
H0529_RS14350	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0529_RS14390	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0529_RS14395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0529_RS14410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0529_RS14420	COG0644	oxidoreductase
H0529_RS14420	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0529_RS14430	COG0425	Belongs to the sulfur carrier protein TusA family
H0529_RS14435	COG4535	Mg2 and Co2 transporter CorC
H0529_RS14445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0529_RS14465	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0529_RS14470	COG0475	glutathione-regulated potassium exporter activity
H0529_RS14470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0529_RS14485	COG0484	heat shock protein binding
H0529_RS14490	COG0789	Transcriptional regulator
H0529_RS14495	COG0598	Magnesium transport protein CorA
H0529_RS14510	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0529_RS14515	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0529_RS14520	COG1074	ATP-dependent DNA helicase activity
H0529_RS14525	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0529_RS14545	COG2226	methyltransferase
H0529_RS14555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0529_RS14560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS14570	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0529_RS14585	COG2111	Na H antiporter
H0529_RS14585	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0529_RS14590	COG1006	Multisubunit Na H antiporter MnhC subunit
H0529_RS14595	COG0651	ATP synthesis coupled electron transport
H0529_RS14600	COG1863	multisubunit Na H antiporter MnhE subunit
H0529_RS14605	COG2212	antiporter activity
H0529_RS14610	COG1320	monovalent cation:proton antiporter activity
H0529_RS14625	COG0195	Participates in both transcription termination and antitermination
H0529_RS14675	COG0237	dephospho-CoA kinase activity
H0529_RS14685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0529_RS14700	COG0497	DNA recombination
H0529_RS14710	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0529_RS14740	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0529_RS14740	COG2169	Transcriptional regulator
H0529_RS14745	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0529_RS14815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0529_RS14830	COG0326	Molecular chaperone. Has ATPase activity
H0529_RS14845	COG2056	Na+-H+ antiporter family
H0529_RS14945	COG0546	phosphoglycolate phosphatase activity
H0529_RS14950	COG1716	ATPase activity
H0529_RS14995	COG0181	hydroxymethylbilane synthase activity
H0529_RS15005	COG3275	phosphorelay sensor kinase activity
H0529_RS15025	COG1538	Outer membrane efflux protein
H0529_RS15030	COG0697	spore germination
H0529_RS15055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0529_RS15060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0529_RS15065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0529_RS15070	COG0772	Belongs to the SEDS family
H0529_RS15095	COG4974	Belongs to the 'phage' integrase family
H0529_RS15100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0529_RS15110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0529_RS15120	COG2197	response regulator
H0529_RS15135	COG0793	Belongs to the peptidase S41A family
H0529_RS15140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0529_RS15145	COG0795	lipopolysaccharide-transporting ATPase activity
H0529_RS15185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0529_RS15185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0529_RS15195	COG0004	ammonium transporteR
H0529_RS15200	COG0347	Belongs to the P(II) protein family
H0529_RS15210	COG0606	chelatase, subunit chli
H0529_RS15215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0529_RS15240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0529_RS15255	COG0318	PFAM AMP-dependent synthetase and ligase
H0529_RS15265	COG0477	Major facilitator Superfamily
H0529_RS15270	COG2860	membrane
H0529_RS15280	COG1253	flavin adenine dinucleotide binding
H0529_RS15290	COG0477	Major facilitator Superfamily
H0529_RS15300	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0529_RS15335	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0529_RS15345	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0529_RS15380	COG1309	transcriptional regulator
H0529_RS15415	COG0758	DNA mediated transformation
H0529_RS15425	COG0697	spore germination
H0529_RS15430	COG1309	transcriptional regulator
H0529_RS15445	COG0386	Belongs to the glutathione peroxidase family
H0529_RS15520	COG1121	(ABC) transporter
H0529_RS15525	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0529_RS15530	COG1280	lysine exporter protein (LysE YggA)
H0529_RS15535	COG2837	iron assimilation
H0529_RS15540	COG0281	malic enzyme
H0529_RS15585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0529_RS15585	COG0519	Catalyzes the synthesis of GMP from XMP
H0529_RS15590	COG4399	Belongs to the UPF0754 family
H0529_RS15595	COG2259	Doxx family
H0529_RS15600	COG0586	Pfam SNARE associated Golgi protein
H0529_RS15615	COG1192	Involved in chromosome partitioning
H0529_RS15625	COG0271	Belongs to the BolA IbaG family
H0529_RS15665	COG3321	synthase
H0529_RS15665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H0529_RS15665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H0529_RS15665	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H0529_RS15670	COG1960	acyl-CoA dehydrogenase activity
H0529_RS15680	COG2197	response regulator
H0529_RS15690	COG3916	Acyl-homoserine-lactone synthase
H0529_RS15695	COG0477	Major facilitator Superfamily
H0529_RS15700	COG1024	Enoyl-CoA hydratase
H0529_RS15705	COG1024	Enoyl-CoA hydratase
H0529_RS15710	COG1960	acyl-CoA dehydrogenase activity
H0529_RS15715	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0529_RS15735	COG1113	amino acid transport
H0529_RS15740	COG1113	amino acid transport
H0529_RS15745	COG0251	oxidation-reduction process
H0529_RS15785	COG0564	pseudouridine synthase activity
H0529_RS15890	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0529_RS15905	COG1802	Transcriptional regulator
H0529_RS15915	COG1448	Aminotransferase
H0529_RS15920	COG0277	FAD linked oxidase domain protein
H0529_RS15930	COG2186	Transcriptional regulator
H0529_RS15940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0529_RS15950	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0529_RS15965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0529_RS15970	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0529_RS15975	COG1216	Glycosyl transferase, family 2
H0529_RS15985	COG1216	Glycosyl transferase, family 2
H0529_RS15995	COG1442	glycosyl transferase family 8
H0529_RS15995	COG1216	Glycosyl transferase, family 2
H0529_RS16005	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0529_RS16010	COG1596	polysaccharide export
H0529_RS16035	COG0728	peptidoglycan biosynthetic process
H0529_RS16040	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0529_RS16095	COG0546	phosphoglycolate phosphatase activity
H0529_RS16100	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS16120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0529_RS16125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0529_RS16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS16135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0529_RS16140	COG1116	anion transmembrane transporter activity
H0529_RS16145	COG1309	transcriptional regulator
H0529_RS16150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0529_RS16160	COG0196	riboflavin kinase activity
H0529_RS16165	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0529_RS16175	COG1047	Peptidyl-prolyl cis-trans
H0529_RS16215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0529_RS16220	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0529_RS16225	COG0596	Alpha beta hydrolase
H0529_RS16250	COG0488	(ABC) transporter
H0529_RS16255	COG0586	Pfam SNARE associated Golgi protein
H0529_RS16265	COG0187	DNA topoisomerase II activity
H0529_RS16275	COG0592	DNA-directed DNA polymerase activity
H0529_RS16305	COG0706	membrane insertase activity
H0529_RS16320	COG1230	cation diffusion facilitator family transporter
H0529_RS16325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0529_RS16340	COG0402	S-adenosylhomocysteine deaminase activity
H0529_RS16350	COG0754	glutathionylspermidine amidase activity
H0529_RS16360	COG0861	Integral membrane protein TerC family
H0529_RS16365	COG0671	phosphoesterase, PA-phosphatase related
H0529_RS16375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0529_RS16390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0529_RS16395	COG2951	lytic endotransglycosylase activity
H0529_RS16445	COG0657	acetylesterase activity
H0529_RS16450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0529_RS16490	COG0733	neurotransmitter:sodium symporter activity
H0529_RS16525	COG0583	DNA-binding transcription factor activity
H0529_RS16530	COG2233	PERMEase
H0529_RS16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS16580	COG2814	Major facilitator Superfamily
H0529_RS16585	COG0656	L-ascorbic acid biosynthetic process
H0529_RS16590	COG0583	DNA-binding transcription factor activity
H0529_RS16605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0529_RS16610	COG1064	alcohol dehydrogenase
H0529_RS16615	COG2818	Glycosylase
H0529_RS16630	COG1194	a g-specific adenine glycosylase
H0529_RS16650	COG2983	Belongs to the UPF0260 family
H0529_RS16655	COG2133	pyrroloquinoline quinone binding
H0529_RS16660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0529_RS16665	COG2116	formate transmembrane transporter activity
H0529_RS16685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0529_RS16690	COG1335	isochorismatase
H0529_RS16695	COG0385	Bile acid
H0529_RS16700	COG0534	Mate efflux family protein
H0529_RS16705	COG1683	Conserved Protein
H0529_RS16725	COG0625	glutathione transferase activity
H0529_RS16735	COG1113	amino acid transport
H0529_RS16745	COG0523	cobalamin synthesis protein
H0529_RS16755	COG2188	Transcriptional regulator
H0529_RS16785	COG0010	Belongs to the arginase family
H0529_RS16800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0529_RS16815	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0529_RS16825	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0529_RS16830	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0529_RS16915	COG0534	Mate efflux family protein
H0529_RS16920	COG0436	Aminotransferase
H0529_RS16925	COG2733	membrane
H0529_RS16940	COG2918	glutathione biosynthetic process
H0529_RS16955	COG5632	N-Acetylmuramoyl-L-alanine amidase
H0529_RS16955	COG3409	Peptidoglycan-binding domain 1 protein
H0529_RS16955	COG1388	LysM domain
H0529_RS17005	COG3150	esterase
H0529_RS17015	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS17020	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H0529_RS17030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0529_RS17040	COG2233	PERMEase
H0529_RS17045	COG2351	hydroxyisourate hydrolase activity
H0529_RS17080	COG3706	GGDEF domain
H0529_RS17095	COG1393	Belongs to the ArsC family
H0529_RS17100	COG0708	Exodeoxyribonuclease III
H0529_RS17125	COG0189	ligase activity
H0529_RS17145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0529_RS17155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0529_RS17170	COG4942	peptidase
H0529_RS17180	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0529_RS17190	COG2119	membrane
H0529_RS17195	COG4774	siderophore transport
H0529_RS17200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS17200	COG0426	domain, Protein
H0529_RS17225	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0529_RS17245	COG1902	pentaerythritol trinitrate reductase activity
H0529_RS17250	COG1519	Transferase
H0529_RS17255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0529_RS17260	COG0668	transmembrane transport
H0529_RS17270	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0529_RS17275	COG1335	isochorismatase
H0529_RS17280	COG1522	sequence-specific DNA binding
H0529_RS17305	COG2205	protein histidine kinase activity
H0529_RS17305	COG2198	Histidine kinase
H0529_RS17305	COG0784	Response regulator, receiver
H0529_RS17310	COG3162	membrane
H0529_RS17315	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0529_RS17325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0529_RS17345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H0529_RS17350	COG1309	transcriptional regulator
H0529_RS17370	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0529_RS17370	COG0351	phosphomethylpyrimidine kinase
H0529_RS17370	COG0352	thiamine-phosphate diphosphorylase activity
H0529_RS17380	COG2814	Major facilitator Superfamily
H0529_RS17395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0529_RS17405	COG1113	amino acid transport
H0529_RS17415	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0529_RS17420	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS17430	COG1335	isochorismatase
H0529_RS17460	COG2814	Major facilitator Superfamily
H0529_RS17465	COG0583	DNA-binding transcription factor activity
H0529_RS17485	COG0667	Aldo Keto reductase
H0529_RS17520	COG1733	regulation of RNA biosynthetic process
H0529_RS17525	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0529_RS17590	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0529_RS17605	COG2329	Antibiotic biosynthesis monooxygenase
H0529_RS17635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0529_RS17665	COG0427	acetyl-CoA hydrolase
H0529_RS17690	COG0659	secondary active sulfate transmembrane transporter activity
H0529_RS17695	COG4221	oxidoreductase activity
H0529_RS17705	COG0488	(ABC) transporter
H0529_RS17790	COG0833	amino acid
H0529_RS17835	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0529_RS17840	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0529_RS17855	COG2226	methyltransferase
H0529_RS17905	COG0070	glutamate synthase
H0529_RS17905	COG0069	glutamate synthase activity
H0529_RS17905	COG0067	glutamate synthase
H0529_RS17910	COG0493	'glutamate synthase
H0529_RS17920	COG1704	LemA family
H0529_RS17925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0529_RS17940	COG3307	-O-antigen
H0529_RS17960	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0529_RS17975	COG0194	GDP metabolic process
H0529_RS18025	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0529_RS18045	COG5380	lipid catabolic process
H0529_RS18050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0529_RS18075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0529_RS18080	COG0277	FAD linked oxidase domain protein
H0529_RS18095	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0529_RS18100	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0529_RS18115	COG1289	transmembrane transporter activity
H0529_RS18125	COG0628	permease
H0529_RS18130	COG1192	Involved in chromosome partitioning
H0529_RS18160	COG0833	amino acid
H0529_RS18165	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0529_RS18170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0529_RS18180	COG1012	belongs to the aldehyde dehydrogenase family
H0529_RS18220	COG0583	DNA-binding transcription factor activity
H0529_RS18240	COG1106	Psort location Cytoplasmic, score
H0529_RS18275	COG0517	IMP dehydrogenase activity
H0529_RS18280	COG1983	PspC domain protein
H0529_RS18290	COG1960	acyl-CoA dehydrogenase activity
H0529_RS18305	COG0408	coproporphyrinogen oxidase activity
H0529_RS18325	COG0513	Belongs to the DEAD box helicase family
H0529_RS18335	COG1127	ABC transporter
H0529_RS18340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0529_RS18350	COG2854	intermembrane phospholipid transfer
H0529_RS18360	COG0598	Magnesium transport protein CorA
H0529_RS18370	COG0494	nUDIX hydrolase
H0529_RS18375	COG1040	competence protein
H0529_RS18380	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0529_RS18400	COG1946	Acyl-CoA thioesterase
H0529_RS18405	COG1301	dicarboxylic acid transport
H0529_RS18420	COG1959	2 iron, 2 sulfur cluster binding
H0529_RS18425	COG1017	nitric oxide dioxygenase activity
H0529_RS18425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS18435	COG0433	COG0433 Predicted ATPase
H0529_RS18595	COG1960	acyl-CoA dehydrogenase activity
H0529_RS18600	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0529_RS18630	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0529_RS18635	COG0339	signal peptide processing
H0529_RS18640	COG0557	exoribonuclease II activity
H0529_RS18685	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0529_RS18690	COG2169	Transcriptional regulator
H0529_RS18695	COG0697	spore germination
H0529_RS18700	COG1295	ribonuclease BN
H0529_RS18735	COG1702	phosphate starvation-inducible protein PhoH
H0529_RS18745	COG1196	nuclear chromosome segregation
H0529_RS18745	COG0741	lytic transglycosylase activity
H0529_RS18745	COG0739	heme binding
H0529_RS18775	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0529_RS18780	COG1183	phosphatidylcholine synthase activity
H0529_RS18825	COG1960	acyl-CoA dehydrogenase activity
H0529_RS18830	COG1309	transcriptional regulator
H0529_RS18845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0529_RS18850	COG1960	acyl-CoA dehydrogenase activity
H0529_RS18870	COG2969	positive regulation of protein catabolic process
H0529_RS18880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0529_RS18895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0529_RS18900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0529_RS18920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0529_RS18930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0529_RS18935	COG1408	metallophosphoesterase
H0529_RS18945	COG2199	diguanylate cyclase activity
H0529_RS19005	COG1607	acyl-coa hydrolase
H0529_RS19035	COG2350	Protein conserved in bacteria
H0529_RS19045	COG0613	PHP domain protein
H0529_RS19050	COG3781	membrane
H0529_RS19060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0529_RS19065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0529_RS19075	COG1862	Preprotein translocase
H0529_RS19110	COG2205	protein histidine kinase activity
H0529_RS19115	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H0529_RS19130	COG0726	polysaccharide deacetylase
H0529_RS19150	COG1091	dTDP-4-dehydrorhamnose reductase activity
H0529_RS19165	COG1215	transferase activity, transferring glycosyl groups
H0529_RS19215	COG1960	acyl-CoA dehydrogenase activity
H0529_RS19220	COG1960	acyl-CoA dehydrogenase activity
H0529_RS19230	COG2205	protein histidine kinase activity
H0529_RS19235	COG0745	RESPONSE REGULATOR receiver
H0529_RS19240	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0529_RS19260	COG2096	Adenosyltransferase
H0529_RS19310	COG0285	dihydrofolate synthase activity
H0529_RS19330	COG0450	alkyl hydroperoxide reductase
H0529_RS19345	COG0477	Major facilitator Superfamily
H0529_RS19350	COG1272	protein, Hemolysin III
H0529_RS19380	COG0183	Belongs to the thiolase family
H0529_RS19385	COG2207	Transcriptional regulator
H0529_RS19405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0529_RS19425	COG0183	Belongs to the thiolase family
H0529_RS19435	COG2885	chlorophyll binding
H0529_RS19435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0529_RS19445	COG1690	Belongs to the RtcB family
H0529_RS19450	COG0833	amino acid
H0529_RS19460	COG2233	PERMEase
H0529_RS19465	COG1217	gtp-binding protein TYPA
H0529_RS19490	COG2094	Belongs to the DNA glycosylase MPG family
H0529_RS19495	COG4772	TonB-dependent receptor
H0529_RS19500	COG1902	pentaerythritol trinitrate reductase activity
H0529_RS19505	COG0679	Auxin Efflux Carrier
H0529_RS19515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0529_RS19520	COG0354	folic acid binding
H0529_RS19530	COG3189	MarR family transcriptional regulator
H0529_RS19535	COG2824	Alkylphosphonate utilization operon protein PhnA
H0529_RS19540	COG3422	double-strand break repair
H0529_RS19580	COG0840	transmembrane signaling receptor activity
H0529_RS19600	COG5510	response to toxic substance
H0529_RS19610	COG2832	Protein of unknown function (DUF454)
H0529_RS19615	COG1376	ErfK ybiS ycfS ynhG family protein
H0529_RS19645	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0529_RS19655	COG1289	transmembrane transporter activity
H0529_RS19660	COG2814	Major facilitator Superfamily
H0529_RS19680	COG1115	amino acid carrier protein
H0529_RS19685	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0529_RS19690	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0529_RS19695	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H0529_RS19700	COG3590	peptidase
H0529_RS19730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0529_RS19740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0529_RS19745	COG1077	Cell shape determining protein MreB Mrl
H0529_RS19750	COG1792	Involved in formation and maintenance of cell shape
H0529_RS19755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0529_RS19760	COG0424	maF-like protein
H0529_RS19765	COG1530	ribonuclease E activity
H0529_RS19775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0529_RS19785	COG0560	Phosphoserine phosphatase
H0529_RS19795	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0529_RS19820	COG2207	Transcriptional regulator
H0529_RS19885	COG0305	Participates in initiation and elongation during chromosome replication
H0529_RS19925	COG0582	viral genome integration into host DNA
H0529_RS19935	COG1113	amino acid transport
H0529_RS19940	COG2828	Protein conserved in bacteria
H0529_RS19945	COG0142	geranyltranstransferase activity
H0529_RS19950	COG2315	Protein conserved in bacteria
H0529_RS19965	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0529_RS19985	COG2194	sulfuric ester hydrolase activity
H0529_RS19990	COG0745	RESPONSE REGULATOR receiver
H0529_RS19995	COG0642	Histidine kinase
H0529_RS20005	COG0004	ammonium transporteR
H0529_RS20010	COG0583	DNA-binding transcription factor activity
H0529_RS20030	COG0525	valine-tRNA ligase activity
H0529_RS20040	COG1028	Short-chain dehydrogenase reductase Sdr
H0529_RS20050	COG0393	Putative heavy-metal-binding
H0529_RS20055	COG0393	Putative heavy-metal-binding
H0529_RS20060	COG1538	Outer membrane efflux protein
H0529_RS20070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS20075	COG0671	phosphoesterase, PA-phosphatase related
H0529_RS20105	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0529_RS20120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0529_RS20120	COG1648	precorrin-2 dehydrogenase activity
H0529_RS20125	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0529_RS20130	COG1733	regulation of RNA biosynthetic process
H0529_RS20140	COG0531	amino acid
H0529_RS20155	COG0321	lipoyl(octanoyl) transferase activity
H0529_RS20160	COG2921	Belongs to the UPF0250 family
H0529_RS20195	COG2009	succinate dehydrogenase
H0529_RS20200	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0529_RS20205	COG1053	succinate dehydrogenase
H0529_RS20210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0529_RS20235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0529_RS20255	COG2354	Protein conserved in bacteria
H0529_RS20260	COG2321	neutral zinc metallopeptidase
H0529_RS20280	COG2843	Capsule synthesis protein
H0529_RS20295	COG0589	response to stress
H0529_RS20315	COG0505	Belongs to the CarA family
H0529_RS20340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0529_RS20345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0529_RS20395	COG0477	Major facilitator Superfamily
H0529_RS20400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0529_RS20415	COG1597	lipid kinase activity
H0529_RS20420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0529_RS20440	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0529_RS20445	COG0584	glycerophosphoryl diester phosphodiesterase
H0529_RS20465	COG0741	lytic transglycosylase activity
H0529_RS20485	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0529_RS20495	COG0583	DNA-binding transcription factor activity
H0529_RS20500	COG2851	Citrate transporter
H0529_RS20540	COG2076	Multidrug Resistance protein
H0529_RS20545	COG0004	ammonium transporteR
H0529_RS20550	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H0529_RS20555	COG3850	Histidine kinase
H0529_RS20560	COG2197	response regulator
H0529_RS20580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0529_RS20590	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H0529_RS20595	COG0347	Belongs to the P(II) protein family
H0529_RS20610	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H0529_RS20625	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0529_RS20625	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H0529_RS20635	COG0004	ammonium transporteR
H0529_RS20650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H0529_RS20655	COG2218	PFAM glutamate synthase alpha subunit domain protein
H0529_RS20660	COG0069	glutamate synthase activity
H0529_RS20740	COG2233	PERMEase
H0529_RS20745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0529_RS20750	COG0251	oxidation-reduction process
H0529_RS20755	COG1335	isochorismatase
H0529_RS20760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0529_RS20765	COG0778	Nitroreductase
H0529_RS20770	COG0596	Alpha beta hydrolase
H0529_RS20785	COG0582	viral genome integration into host DNA
H0529_RS20795	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0529_RS20805	COG3811	Belongs to the UPF0386 family
H0529_RS20825	COG0778	Nitroreductase
H0529_RS20840	COG1929	Belongs to the glycerate kinase type-1 family
H0529_RS20845	COG0243	molybdopterin cofactor binding
H0529_RS20850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0529_RS20855	COG3339	Conserved Protein
H0529_RS20865	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H0529_RS20880	COG1113	amino acid transport
H0529_RS20890	COG0019	diaminopimelate decarboxylase activity
H0529_RS20900	COG1280	lysine exporter protein (LysE YggA)
H0529_RS20905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0529_RS20935	COG0463	Glycosyl transferase, family 2
H0529_RS20955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0529_RS20990	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0529_RS20995	COG1136	(ABC) transporter
H0529_RS21000	COG0658	competence protein
H0529_RS21000	COG2333	competence protein COMEC
H0529_RS21010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0529_RS21010	COG0616	signal peptide processing
H0529_RS21015	COG0596	Alpha beta hydrolase
H0529_RS21020	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0529_RS21030	COG0628	permease
H0529_RS21045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0529_RS21050	COG1538	Outer membrane efflux protein
H0529_RS21085	COG1660	Displays ATPase and GTPase activities
H0529_RS21145	COG0739	heme binding
H0529_RS21220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0529_RS21330	COG2015	COG2015, Alkyl sulfatase and related hydrolases
H0529_RS21340	COG3293	Transposase
H0529_RS21395	COG2826	transposase and inactivated derivatives, IS30 family
H0529_RS21415	COG0673	inositol 2-dehydrogenase activity
H0529_RS21420	COG1324	tolerance protein
H0529_RS21445	COG2826	transposase and inactivated derivatives, IS30 family
H0529_RS21530	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H0529_RS21550	COG2184	nucleotidyltransferase activity
H0529_RS21560	COG4974	Belongs to the 'phage' integrase family
H0529_RS21640	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0529_RS21645	COG0501	Belongs to the peptidase M48B family
H0529_RS21785	COG3657	addiction module killer protein
H0529_RS21790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0529_RS21795	COG0659	secondary active sulfate transmembrane transporter activity
H0529_RS21860	COG0488	(ABC) transporter
H0529_RS21865	COG3173	Aminoglycoside phosphotransferase
H0529_RS21880	COG2205	protein histidine kinase activity
H0529_RS21885	COG0745	RESPONSE REGULATOR receiver
H0529_RS22050	COG3550	peptidyl-serine autophosphorylation