locus-tag	class	description
ACICU_RS00010	COG0187	DNA topoisomerase II activity
ACICU_RS00020	COG0592	DNA-directed DNA polymerase activity
ACICU_RS00045	COG0706	membrane insertase activity
ACICU_RS00060	COG1230	cation diffusion facilitator family transporter
ACICU_RS00065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_RS00085	COG0402	S-adenosylhomocysteine deaminase activity
ACICU_RS00095	COG0754	glutathionylspermidine amidase activity
ACICU_RS00110	COG0861	Integral membrane protein TerC family
ACICU_RS00115	COG0671	phosphoesterase, PA-phosphatase related
ACICU_RS00125	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACICU_RS00140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACICU_RS00145	COG2951	lytic endotransglycosylase activity
ACICU_RS00175	COG0583	DNA-binding transcription factor activity
ACICU_RS00195	COG0657	acetylesterase activity
ACICU_RS00200	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACICU_RS00240	COG1047	Peptidyl-prolyl cis-trans
ACICU_RS00250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACICU_RS00255	COG0196	riboflavin kinase activity
ACICU_RS00265	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACICU_RS00270	COG1309	transcriptional regulator
ACICU_RS00275	COG1116	anion transmembrane transporter activity
ACICU_RS00280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_RS00285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_RS00290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_RS00295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_RS00315	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS00320	COG0546	phosphoglycolate phosphatase activity
ACICU_RS00375	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACICU_RS00380	COG0728	peptidoglycan biosynthetic process
ACICU_RS00405	COG1596	polysaccharide export
ACICU_RS00410	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACICU_RS00415	COG1086	Polysaccharide biosynthesis protein
ACICU_RS00420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACICU_RS00425	COG1083	cytidylyl-transferase
ACICU_RS00440	COG2089	acid synthase
ACICU_RS00475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACICU_RS00480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACICU_RS00495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACICU_RS00500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACICU_RS00510	COG2186	Transcriptional regulator
ACICU_RS00520	COG0277	FAD linked oxidase domain protein
ACICU_RS00525	COG1448	Aminotransferase
ACICU_RS00530	COG1802	Transcriptional regulator
ACICU_RS00545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACICU_RS00620	COG0564	pseudouridine synthase activity
ACICU_RS00660	COG0251	oxidation-reduction process
ACICU_RS00665	COG1113	amino acid transport
ACICU_RS00670	COG1113	amino acid transport
ACICU_RS00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_RS00695	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS00700	COG1024	Enoyl-CoA hydratase
ACICU_RS00705	COG1024	Enoyl-CoA hydratase
ACICU_RS00710	COG0477	Major facilitator Superfamily
ACICU_RS00715	COG3916	Acyl-homoserine-lactone synthase
ACICU_RS00725	COG2197	response regulator
ACICU_RS00735	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS00740	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACICU_RS00740	COG3321	synthase
ACICU_RS00740	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ACICU_RS00740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACICU_RS00775	COG0271	Belongs to the BolA IbaG family
ACICU_RS00785	COG1192	Involved in chromosome partitioning
ACICU_RS00800	COG0586	Pfam SNARE associated Golgi protein
ACICU_RS00805	COG2259	Doxx family
ACICU_RS00810	COG4399	Belongs to the UPF0754 family
ACICU_RS00815	COG0519	Catalyzes the synthesis of GMP from XMP
ACICU_RS00815	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACICU_RS00860	COG0281	malic enzyme
ACICU_RS00865	COG2837	iron assimilation
ACICU_RS00870	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS00875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACICU_RS00880	COG1121	(ABC) transporter
ACICU_RS00950	COG0386	Belongs to the glutathione peroxidase family
ACICU_RS00965	COG1309	transcriptional regulator
ACICU_RS00970	COG0697	spore germination
ACICU_RS00980	COG0758	DNA mediated transformation
ACICU_RS01015	COG1309	transcriptional regulator
ACICU_RS01050	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACICU_RS01060	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACICU_RS01095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACICU_RS01105	COG2814	Major facilitator Superfamily
ACICU_RS01115	COG1253	flavin adenine dinucleotide binding
ACICU_RS01120	COG3012	SEC-C Motif Domain Protein
ACICU_RS01125	COG2860	membrane
ACICU_RS01130	COG0477	Major facilitator Superfamily
ACICU_RS01140	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_RS01155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACICU_RS01230	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACICU_RS01245	COG0789	Transcriptional regulator
ACICU_RS01270	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_RS01280	COG0606	chelatase, subunit chli
ACICU_RS01290	COG0347	Belongs to the P(II) protein family
ACICU_RS01295	COG0004	ammonium transporteR
ACICU_RS01305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACICU_RS01305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACICU_RS01345	COG0795	lipopolysaccharide-transporting ATPase activity
ACICU_RS01350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACICU_RS01355	COG0793	Belongs to the peptidase S41A family
ACICU_RS01370	COG2197	response regulator
ACICU_RS01380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACICU_RS01390	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_RS01395	COG4974	Belongs to the 'phage' integrase family
ACICU_RS01420	COG0772	Belongs to the SEDS family
ACICU_RS01425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACICU_RS01430	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACICU_RS01435	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACICU_RS01460	COG0697	spore germination
ACICU_RS01465	COG1538	Outer membrane efflux protein
ACICU_RS01485	COG3275	phosphorelay sensor kinase activity
ACICU_RS01495	COG0181	hydroxymethylbilane synthase activity
ACICU_RS01540	COG1716	ATPase activity
ACICU_RS01545	COG0546	phosphoglycolate phosphatase activity
ACICU_RS01640	COG0596	Alpha beta hydrolase
ACICU_RS01645	COG2056	Na+-H+ antiporter family
ACICU_RS01660	COG0326	Molecular chaperone. Has ATPase activity
ACICU_RS01675	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACICU_RS01740	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACICU_RS01745	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACICU_RS01745	COG2169	Transcriptional regulator
ACICU_RS01775	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACICU_RS01785	COG0497	DNA recombination
ACICU_RS01800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACICU_RS01810	COG0237	dephospho-CoA kinase activity
ACICU_RS01860	COG0195	Participates in both transcription termination and antitermination
ACICU_RS01875	COG1320	monovalent cation:proton antiporter activity
ACICU_RS01880	COG2212	antiporter activity
ACICU_RS01885	COG1863	multisubunit Na H antiporter MnhE subunit
ACICU_RS01890	COG0651	ATP synthesis coupled electron transport
ACICU_RS01895	COG1006	Multisubunit Na H antiporter MnhC subunit
ACICU_RS01900	COG2111	Na H antiporter
ACICU_RS01900	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACICU_RS01915	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACICU_RS01920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_RS01935	COG2226	methyltransferase
ACICU_RS01955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACICU_RS01960	COG1074	ATP-dependent DNA helicase activity
ACICU_RS01965	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACICU_RS01970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACICU_RS01990	COG0789	Transcriptional regulator
ACICU_RS01995	COG0484	heat shock protein binding
ACICU_RS02005	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACICU_RS02010	COG0475	glutathione-regulated potassium exporter activity
ACICU_RS02010	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_RS02015	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACICU_RS02035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_RS02045	COG4535	Mg2 and Co2 transporter CorC
ACICU_RS02050	COG0425	Belongs to the sulfur carrier protein TusA family
ACICU_RS02055	COG0644	oxidoreductase
ACICU_RS02055	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACICU_RS02065	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACICU_RS02080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_RS02085	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACICU_RS02120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACICU_RS02135	COG0534	Mate efflux family protein
ACICU_RS02145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACICU_RS02150	COG4221	oxidoreductase activity
ACICU_RS02155	COG0583	DNA-binding transcription factor activity
ACICU_RS02170	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_RS02175	COG1530	ribonuclease E activity
ACICU_RS02185	COG0546	phosphoglycolate phosphatase activity
ACICU_RS02190	COG2378	regulation of single-species biofilm formation
ACICU_RS02195	COG0625	glutathione transferase activity
ACICU_RS02205	COG0583	DNA-binding transcription factor activity
ACICU_RS02270	COG0473	3-isopropylmalate dehydrogenase activity
ACICU_RS02325	COG1301	dicarboxylic acid transport
ACICU_RS02335	COG1560	Kdo2-lipid A biosynthetic process
ACICU_RS02340	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS02345	COG0488	(ABC) transporter
ACICU_RS02350	COG2900	Belongs to the SlyX family
ACICU_RS02360	COG1733	regulation of RNA biosynthetic process
ACICU_RS02385	COG0210	DNA helicase
ACICU_RS02390	COG0724	RNA recognition motif
ACICU_RS02410	COG4651	solute:proton antiporter activity
ACICU_RS02410	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_RS02435	COG0788	formyltetrahydrofolate deformylase activity
ACICU_RS02535	COG2813	Specifically methylates the guanine in position
ACICU_RS02535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_RS02545	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACICU_RS02555	COG4774	siderophore transport
ACICU_RS02565	COG0740	serine-type endopeptidase activity
ACICU_RS02585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACICU_RS02585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACICU_RS02590	COG0280	phosphate acetyltransferase
ACICU_RS02590	COG0857	belongs to the CobB CobQ family
ACICU_RS02595	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACICU_RS02605	COG0800	Aldolase
ACICU_RS02615	COG3265	gluconokinase activity
ACICU_RS02620	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS02630	COG2267	carboxylic ester hydrolase activity
ACICU_RS02645	COG0793	Belongs to the peptidase S41A family
ACICU_RS02680	COG1426	Protein conserved in bacteria
ACICU_RS02725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACICU_RS02735	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_RS02750	COG2986	histidine ammonia-lyase
ACICU_RS02790	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS02795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACICU_RS02815	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACICU_RS02825	COG1162	GTPase activity
ACICU_RS02830	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACICU_RS02845	COG1538	Outer membrane efflux protein
ACICU_RS02850	COG0577	efflux transmembrane transporter activity
ACICU_RS02850	COG1136	(ABC) transporter
ACICU_RS02855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS02880	COG0028	Belongs to the TPP enzyme family
ACICU_RS02885	COG0440	acetolactate synthase activity
ACICU_RS02915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACICU_RS02930	COG0084	hydrolase, TatD family'
ACICU_RS02945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACICU_RS02950	COG0583	DNA-binding transcription factor activity
ACICU_RS02960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACICU_RS02965	COG2814	Major facilitator Superfamily
ACICU_RS02975	COG0697	spore germination
ACICU_RS03005	COG3622	Belongs to the hyi family
ACICU_RS03010	COG2084	Dehydrogenase
ACICU_RS03015	COG1024	Enoyl-CoA hydratase
ACICU_RS03020	COG5002	protein histidine kinase activity
ACICU_RS03020	COG2205	protein histidine kinase activity
ACICU_RS03020	COG0784	Response regulator, receiver
ACICU_RS03040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACICU_RS03050	COG3956	TIGRFAM MazG family protein
ACICU_RS03055	COG1555	photosystem II stabilization
ACICU_RS03060	COG0617	tRNA 3'-terminal CCA addition
ACICU_RS03065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACICU_RS03085	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACICU_RS03090	COG3028	Belongs to the UPF0307 family
ACICU_RS03095	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_RS03110	COG0625	glutathione transferase activity
ACICU_RS03115	COG1238	metal cluster binding
ACICU_RS03155	COG0072	phenylalanine-tRNA ligase activity
ACICU_RS03180	COG0248	Ppx GppA phosphatase
ACICU_RS03190	COG0037	tRNA processing
ACICU_RS03230	COG1764	response to oxidative stress
ACICU_RS03235	COG1846	Transcriptional regulator
ACICU_RS03245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACICU_RS03305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACICU_RS03310	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACICU_RS03315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACICU_RS03325	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACICU_RS03375	COG1214	PFAM Peptidase M22, glycoprotease
ACICU_RS03400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACICU_RS03405	COG0561	phosphatase activity
ACICU_RS03415	COG2132	Multicopper oxidase
ACICU_RS03420	COG3667	copper resistance
ACICU_RS03435	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACICU_RS03440	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACICU_RS03445	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACICU_RS03475	COG1063	alcohol dehydrogenase
ACICU_RS03480	COG0583	DNA-binding transcription factor activity
ACICU_RS03485	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS03490	COG2814	Major facilitator Superfamily
ACICU_RS03495	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACICU_RS03505	COG1053	succinate dehydrogenase
ACICU_RS03510	COG0583	DNA-binding transcription factor activity
ACICU_RS03525	COG0583	DNA-binding transcription factor activity
ACICU_RS03550	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS03555	COG0583	DNA-binding transcription factor activity
ACICU_RS03570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_RS03595	COG0384	phenazine biosynthesis protein PhzF
ACICU_RS03605	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS03620	COG4993	Dehydrogenase
ACICU_RS03690	COG2205	protein histidine kinase activity
ACICU_RS03700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACICU_RS03720	COG0745	RESPONSE REGULATOR receiver
ACICU_RS03760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACICU_RS03790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACICU_RS03795	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACICU_RS03815	COG0583	DNA-binding transcription factor activity
ACICU_RS03835	COG0668	transmembrane transport
ACICU_RS03845	COG2081	HI0933 family
ACICU_RS03850	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACICU_RS03880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_RS03880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACICU_RS03890	COG0489	protein tyrosine kinase activity
ACICU_RS03940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACICU_RS03950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACICU_RS03965	COG0730	response to heat
ACICU_RS03975	COG1196	nuclear chromosome segregation
ACICU_RS03995	COG2223	nitrite transmembrane transporter activity
ACICU_RS04000	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACICU_RS04005	COG1877	trehalose-phosphatase activity
ACICU_RS04010	COG0596	Alpha beta hydrolase
ACICU_RS04010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_RS04010	COG2226	methyltransferase
ACICU_RS04025	COG4106	trans-aconitate 2-methyltransferase activity
ACICU_RS04040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACICU_RS04045	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACICU_RS04050	COG0009	L-threonylcarbamoyladenylate synthase
ACICU_RS04055	COG3101	peptidyl-lysine hydroxylation
ACICU_RS04060	COG1399	metal-binding, possibly nucleic acid-binding protein
ACICU_RS04085	COG1652	LysM domain
ACICU_RS04090	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACICU_RS04090	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_RS04090	COG0351	phosphomethylpyrimidine kinase
ACICU_RS04100	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACICU_RS04130	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACICU_RS04145	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACICU_RS04160	COG0358	DNA primase activity
ACICU_RS04195	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACICU_RS04210	COG0583	DNA-binding transcription factor activity
ACICU_RS04215	COG0473	3-isopropylmalate dehydrogenase activity
ACICU_RS04225	COG0657	acetylesterase activity
ACICU_RS04235	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS04255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACICU_RS04255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACICU_RS04270	COG1981	membrane
ACICU_RS04315	COG0456	acetyltransferase
ACICU_RS04325	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACICU_RS04330	COG0492	ferredoxin-NADP+ reductase activity
ACICU_RS04335	COG1674	ftsk spoiiie
ACICU_RS04335	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACICU_RS04340	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS04360	COG2894	cell division
ACICU_RS04375	COG0204	Acyl-transferase
ACICU_RS04380	COG2885	chlorophyll binding
ACICU_RS04385	COG0210	DNA helicase
ACICU_RS04395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACICU_RS04410	COG0121	glutamine amidotransferase
ACICU_RS04430	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACICU_RS04435	COG0735	belongs to the Fur family
ACICU_RS04460	COG0420	3'-5' exonuclease activity
ACICU_RS04480	COG1090	epimerase
ACICU_RS04495	COG2050	protein possibly involved in aromatic compounds catabolism
ACICU_RS04505	COG2814	Major facilitator Superfamily
ACICU_RS04510	COG0405	Gamma-glutamyltransferase
ACICU_RS04545	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS04555	COG0477	Major facilitator Superfamily
ACICU_RS04560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_RS04570	COG1595	DNA-templated transcription, initiation
ACICU_RS04625	COG0531	amino acid
ACICU_RS04630	COG2040	homocysteine
ACICU_RS04655	COG1309	transcriptional regulator
ACICU_RS04660	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_RS04665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_RS04675	COG1607	acyl-coa hydrolase
ACICU_RS04685	COG0523	cobalamin synthesis protein
ACICU_RS04695	COG4681	YaeQ
ACICU_RS04705	COG0726	polysaccharide deacetylase
ACICU_RS04705	COG1649	PFAM Uncharacterised BCR, COG1649
ACICU_RS04710	COG1215	transferase activity, transferring glycosyl groups
ACICU_RS04720	COG1024	Enoyl-CoA hydratase
ACICU_RS04735	COG1414	Transcriptional regulator
ACICU_RS04755	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_RS04770	COG2271	Major facilitator Superfamily
ACICU_RS04780	COG2267	carboxylic ester hydrolase activity
ACICU_RS04785	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS04800	COG0028	Belongs to the TPP enzyme family
ACICU_RS04810	COG0477	Major facilitator Superfamily
ACICU_RS04815	COG0242	peptide deformylase activity
ACICU_RS04820	COG2066	Belongs to the glutaminase family
ACICU_RS04825	COG2207	Transcriptional regulator
ACICU_RS04830	COG2223	nitrite transmembrane transporter activity
ACICU_RS04845	COG0583	DNA-binding transcription factor activity
ACICU_RS04850	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS04855	COG2271	Major facilitator Superfamily
ACICU_RS04860	COG3959	Transketolase, thiamine diphosphate binding domain
ACICU_RS04865	COG3958	Transketolase
ACICU_RS04875	COG0306	phosphate transporter
ACICU_RS04895	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACICU_RS04940	COG4181	ATPase activity
ACICU_RS04945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACICU_RS04970	COG0583	DNA-binding transcription factor activity
ACICU_RS04980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_RS04985	COG1773	rubredoxin
ACICU_RS05030	COG2851	Citrate transporter
ACICU_RS05040	COG1253	flavin adenine dinucleotide binding
ACICU_RS05090	COG0830	nickel cation binding
ACICU_RS05105	COG0742	ribosomal rna small subunit methyltransferase
ACICU_RS05110	COG0768	penicillin binding
ACICU_RS05130	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACICU_RS05135	COG2878	Part of a membrane complex involved in electron transport
ACICU_RS05140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACICU_RS05150	COG3384	dioxygenase
ACICU_RS05175	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACICU_RS05540	COG2194	sulfuric ester hydrolase activity
ACICU_RS05570	COG0006	proline dipeptidase activity
ACICU_RS05575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_RS05580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_RS05600	COG1279	arginine transmembrane transporter activity
ACICU_RS05605	COG0583	DNA-binding transcription factor activity
ACICU_RS05645	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_RS05650	COG0741	lytic transglycosylase activity
ACICU_RS05650	COG1388	LysM domain
ACICU_RS05650	COG0741	lytic transglycosylase activity
ACICU_RS05650	COG1388	LysM domain
ACICU_RS05660	COG4174	ABC transporter (Permease)
ACICU_RS05665	COG4239	(ABC) transporter, permease
ACICU_RS05670	COG4172	Belongs to the ABC transporter superfamily
ACICU_RS05690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_RS05700	COG4251	negative regulation of phosphorylation
ACICU_RS05700	COG5001	Diguanylate cyclase
ACICU_RS05700	COG2203	Gaf domain
ACICU_RS05700	COG3706	GGDEF domain
ACICU_RS05710	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_RS05710	COG1902	pentaerythritol trinitrate reductase activity
ACICU_RS05725	COG4269	membrane
ACICU_RS05750	COG3209	COG3209 Rhs family protein
ACICU_RS05795	COG1113	amino acid transport
ACICU_RS05805	COG0531	amino acid
ACICU_RS05825	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS05845	COG1113	amino acid transport
ACICU_RS05865	COG1309	transcriptional regulator
ACICU_RS05870	COG1741	Belongs to the pirin family
ACICU_RS05885	COG2072	flavoprotein involved in K transport
ACICU_RS05895	COG2252	PERMEase
ACICU_RS05900	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACICU_RS05905	COG3038	cytochrome b561
ACICU_RS05915	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACICU_RS05925	COG0527	aspartate kinase activity
ACICU_RS05935	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACICU_RS05945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACICU_RS05960	COG0667	Aldo Keto reductase
ACICU_RS05970	COG1765	OsmC-like protein
ACICU_RS05985	COG0542	response to heat
ACICU_RS06020	COG2885	chlorophyll binding
ACICU_RS06030	COG0625	glutathione transferase activity
ACICU_RS06035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACICU_RS06055	COG3634	alkyl hydroperoxide reductase activity
ACICU_RS06065	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACICU_RS06075	COG0450	alkyl hydroperoxide reductase
ACICU_RS06080	COG1643	Atp-dependent helicase
ACICU_RS06095	COG2814	Major facilitator Superfamily
ACICU_RS06100	COG3135	benzoate transporter
ACICU_RS06105	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS06110	COG0543	2 iron, 2 sulfur cluster binding
ACICU_RS06110	COG0633	Ferredoxin
ACICU_RS06115	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACICU_RS06120	COG4638	Rieske (2fe-2S)
ACICU_RS06125	COG0583	DNA-binding transcription factor activity
ACICU_RS06175	COG1570	exodeoxyribonuclease VII activity
ACICU_RS06210	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS06215	COG1278	Cold shock
ACICU_RS06245	COG2814	Major facilitator Superfamily
ACICU_RS06285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACICU_RS06285	COG0517	IMP dehydrogenase activity
ACICU_RS06290	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACICU_RS06300	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACICU_RS06305	COG1137	ATPase activity
ACICU_RS06310	COG1538	Outer membrane efflux protein
ACICU_RS06340	COG4122	O-methyltransferase activity
ACICU_RS06350	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACICU_RS06385	COG5006	permease, DMT superfamily
ACICU_RS06395	COG1560	Kdo2-lipid A biosynthetic process
ACICU_RS06405	COG2814	Major facilitator Superfamily
ACICU_RS06425	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_RS06470	COG0583	DNA-binding transcription factor activity
ACICU_RS06475	COG1914	H( )-stimulated, divalent metal cation uptake system
ACICU_RS06495	COG4770	biotin carboxylase activity
ACICU_RS06500	COG0038	chloride channel
ACICU_RS06535	COG1063	alcohol dehydrogenase
ACICU_RS06550	COG0439	Biotin carboxylase
ACICU_RS06555	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_RS06560	COG1733	regulation of RNA biosynthetic process
ACICU_RS06575	COG0864	Transcriptional regulator
ACICU_RS06585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_RS06590	COG1116	anion transmembrane transporter activity
ACICU_RS06710	COG2807	transmembrane transport
ACICU_RS06725	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACICU_RS06735	COG0789	Transcriptional regulator
ACICU_RS06745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_RS06765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_RS06775	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_RS06790	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS06795	COG0531	amino acid
ACICU_RS06800	COG1760	l-serine dehydratase
ACICU_RS06805	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS06805	COG2030	dehydratase
ACICU_RS06810	COG3396	Phenylacetate-CoA oxygenase
ACICU_RS06815	COG3460	Phenylacetate-CoA oxygenase
ACICU_RS06820	COG3396	Phenylacetate-CoA oxygenase
ACICU_RS06825	COG2151	metal-sulfur cluster biosynthetic enzyme
ACICU_RS06830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_RS06835	COG1024	Enoyl-CoA hydratase
ACICU_RS06840	COG1024	Enoyl-CoA hydratase
ACICU_RS06845	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_RS06850	COG0183	Belongs to the thiolase family
ACICU_RS06855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACICU_RS06860	COG3327	negative regulation of DNA-templated transcription, initiation
ACICU_RS06870	COG2050	protein possibly involved in aromatic compounds catabolism
ACICU_RS06900	COG0753	catalase activity
ACICU_RS06905	COG3038	cytochrome b561
ACICU_RS06925	COG2267	carboxylic ester hydrolase activity
ACICU_RS06930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_RS06935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_RS06940	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS06945	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACICU_RS06960	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACICU_RS06965	COG0583	DNA-binding transcription factor activity
ACICU_RS06975	COG1414	Transcriptional regulator
ACICU_RS06980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_RS06990	COG1840	ABC-type Fe3 transport system, periplasmic component
ACICU_RS06995	COG3842	ATPase activity
ACICU_RS07010	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACICU_RS07015	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACICU_RS07020	COG2814	Major facilitator Superfamily
ACICU_RS07025	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS07040	COG1024	Enoyl-CoA hydratase
ACICU_RS07050	COG2814	Major facilitator Superfamily
ACICU_RS07060	COG0183	Belongs to the thiolase family
ACICU_RS07065	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACICU_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS07075	COG1024	Enoyl-CoA hydratase
ACICU_RS07080	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS07085	COG2814	Major facilitator Superfamily
ACICU_RS07090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_RS07095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_RS07115	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS07130	COG0583	DNA-binding transcription factor activity
ACICU_RS07140	COG4770	biotin carboxylase activity
ACICU_RS07145	COG1024	Enoyl-CoA hydratase
ACICU_RS07150	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACICU_RS07155	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS07160	COG1309	transcriptional regulator
ACICU_RS07165	COG0318	PFAM AMP-dependent synthetase and ligase
ACICU_RS07185	COG0583	DNA-binding transcription factor activity
ACICU_RS07235	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS07255	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACICU_RS07275	COG0784	Response regulator, receiver
ACICU_RS07275	COG2205	protein histidine kinase activity
ACICU_RS07290	COG0765	amino acid transport
ACICU_RS07295	COG0765	amino acid transport
ACICU_RS07300	COG1126	abc transporter atp-binding protein
ACICU_RS07305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_RS07310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACICU_RS07320	COG1280	lysine exporter protein (LysE YggA)
ACICU_RS07325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACICU_RS07330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACICU_RS07335	COG1045	serine acetyltransferase
ACICU_RS07350	COG0583	DNA-binding transcription factor activity
ACICU_RS07355	COG0625	glutathione transferase activity
ACICU_RS07360	COG0625	glutathione transferase activity
ACICU_RS07365	COG0583	DNA-binding transcription factor activity
ACICU_RS07375	COG1346	cytolysis
ACICU_RS07395	COG2814	Major facilitator Superfamily
ACICU_RS07405	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACICU_RS07410	COG3052	prosthetic group binding
ACICU_RS07430	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACICU_RS07450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_RS07460	COG1294	oxidase, subunit
ACICU_RS07465	COG1271	oxidase subunit
ACICU_RS07485	COG0477	Major facilitator Superfamily
ACICU_RS07495	COG4521	taurine ABC transporter
ACICU_RS07500	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACICU_RS07505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_RS07510	COG2175	clavaminate synthase activity
ACICU_RS07520	COG1953	Uracil, thiamine, allantoin
ACICU_RS07530	COG0583	DNA-binding transcription factor activity
ACICU_RS07540	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACICU_RS07555	COG0640	Transcriptional regulator
ACICU_RS07560	COG0798	PFAM Bile acid sodium symporter
ACICU_RS07565	COG0583	DNA-binding transcription factor activity
ACICU_RS07580	COG3634	alkyl hydroperoxide reductase activity
ACICU_RS07620	COG0436	Aminotransferase
ACICU_RS07630	COG0386	Belongs to the glutathione peroxidase family
ACICU_RS07670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACICU_RS07695	COG0012	GTP binding
ACICU_RS07700	COG2011	ABC-type metal ion transport system permease component
ACICU_RS07705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACICU_RS07715	COG1464	Belongs to the NlpA lipoprotein family
ACICU_RS07745	COG0765	amino acid transport
ACICU_RS07750	COG0765	amino acid transport
ACICU_RS07755	COG1126	abc transporter atp-binding protein
ACICU_RS07765	COG1522	sequence-specific DNA binding
ACICU_RS07780	COG1309	transcriptional regulator
ACICU_RS07800	COG0583	DNA-binding transcription factor activity
ACICU_RS07810	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACICU_RS07820	COG0697	spore germination
ACICU_RS07845	COG3121	Chaperone
ACICU_RS07850	COG3539	Fimbrial protein
ACICU_RS07875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACICU_RS07875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACICU_RS07920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACICU_RS07930	COG2353	YceI-like domain
ACICU_RS07955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACICU_RS07960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACICU_RS07960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACICU_RS07960	COG0506	proline dehydrogenase activity
ACICU_RS07970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACICU_RS07975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACICU_RS07995	COG1132	(ABC) transporter
ACICU_RS08000	COG3122	Protein conserved in bacteria
ACICU_RS08005	COG3619	membrane
ACICU_RS08015	COG0640	Transcriptional regulator
ACICU_RS08025	COG2850	peptidyl-arginine hydroxylation
ACICU_RS08030	COG0424	maF-like protein
ACICU_RS08050	COG0191	fructose-bisphosphate aldolase activity
ACICU_RS08055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACICU_RS08070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACICU_RS08080	COG1192	Involved in chromosome partitioning
ACICU_RS08085	COG1475	DNA binding
ACICU_RS08090	COG0811	peptide transport
ACICU_RS08100	COG1132	(ABC) transporter
ACICU_RS08105	COG1663	tetraacyldisaccharide 4'-kinase activity
ACICU_RS08125	COG0084	hydrolase, TatD family'
ACICU_RS08190	COG0776	regulation of translation
ACICU_RS08220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACICU_RS08225	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACICU_RS08270	COG0339	signal peptide processing
ACICU_RS08280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACICU_RS08315	COG0702	epimerase
ACICU_RS08320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACICU_RS08340	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACICU_RS08370	COG0316	Belongs to the HesB IscA family
ACICU_RS08375	COG0822	iron-sulfur transferase activity
ACICU_RS08400	COG0776	regulation of translation
ACICU_RS08405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACICU_RS08410	COG2207	Transcriptional regulator
ACICU_RS08415	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACICU_RS08420	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS08425	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS08440	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACICU_RS08460	COG4264	IucA IucC family
ACICU_RS08465	COG4264	IucA IucC family
ACICU_RS08505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACICU_RS08520	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACICU_RS08540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACICU_RS08545	COG0730	response to heat
ACICU_RS08565	COG4773	Receptor
ACICU_RS08570	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_RS08585	COG1131	(ABC) transporter
ACICU_RS08590	COG0842	Transport permease protein
ACICU_RS08595	COG0842	Transport permease protein
ACICU_RS08675	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACICU_RS08710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACICU_RS08720	COG0133	tryptophan synthase activity
ACICU_RS08735	COG3706	GGDEF domain
ACICU_RS08750	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACICU_RS08755	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACICU_RS08760	COG0022	dehydrogenase e1 component
ACICU_RS08765	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACICU_RS08770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_RS08780	COG1063	alcohol dehydrogenase
ACICU_RS08785	COG3781	membrane
ACICU_RS08795	COG3453	Protein conserved in bacteria
ACICU_RS08795	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_RS08805	COG0730	response to heat
ACICU_RS08820	COG2207	Transcriptional regulator
ACICU_RS08820	COG3708	Transcriptional regulator
ACICU_RS08825	COG1733	regulation of RNA biosynthetic process
ACICU_RS08830	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACICU_RS08840	COG2188	Transcriptional regulator
ACICU_RS08855	COG4521	taurine ABC transporter
ACICU_RS08860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_RS08880	COG0477	Major facilitator Superfamily
ACICU_RS08890	COG1027	Aspartate ammonia-lyase
ACICU_RS08905	COG0583	DNA-binding transcription factor activity
ACICU_RS08910	COG0583	DNA-binding transcription factor activity
ACICU_RS08915	COG0183	Belongs to the thiolase family
ACICU_RS08920	COG2031	fatty acid transporter
ACICU_RS08925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_RS08935	COG0583	DNA-binding transcription factor activity
ACICU_RS08945	COG2610	gluconate transmembrane transporter activity
ACICU_RS08950	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS08955	COG2207	Transcriptional regulator
ACICU_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS08995	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_RS08995	COG0543	2 iron, 2 sulfur cluster binding
ACICU_RS09000	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACICU_RS09005	COG4638	Rieske (2fe-2S)
ACICU_RS09015	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACICU_RS09020	COG4149	molybdate abc transporter
ACICU_RS09025	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACICU_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS09035	COG3433	isochorismatase activity
ACICU_RS09035	COG1535	isochorismatase
ACICU_RS09095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACICU_RS09110	COG0753	catalase activity
ACICU_RS09120	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACICU_RS09145	COG3539	Fimbrial protein
ACICU_RS09165	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_RS09185	COG2072	flavoprotein involved in K transport
ACICU_RS09195	COG1538	Outer membrane efflux protein
ACICU_RS09200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACICU_RS09205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS09210	COG0745	RESPONSE REGULATOR receiver
ACICU_RS09215	COG2205	protein histidine kinase activity
ACICU_RS09225	COG2207	Transcriptional regulator
ACICU_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS09290	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACICU_RS09405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACICU_RS09425	COG1120	ATPase activity
ACICU_RS09430	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACICU_RS09440	COG1064	alcohol dehydrogenase
ACICU_RS09455	COG2207	Transcriptional regulator
ACICU_RS09460	COG2084	Dehydrogenase
ACICU_RS09470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACICU_RS09475	COG0583	DNA-binding transcription factor activity
ACICU_RS09485	COG0129	dihydroxy-acid dehydratase activity
ACICU_RS09490	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS09505	COG1566	PFAM secretion protein HlyD family protein
ACICU_RS09525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACICU_RS09555	COG0583	DNA-binding transcription factor activity
ACICU_RS09570	COG2188	Transcriptional regulator
ACICU_RS09600	COG3210	domain, Protein
ACICU_RS09605	COG2831	hemolysin activation secretion protein
ACICU_RS09615	COG1473	amidohydrolase
ACICU_RS09625	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACICU_RS09625	COG0475	glutathione-regulated potassium exporter activity
ACICU_RS09635	COG0583	DNA-binding transcription factor activity
ACICU_RS09640	COG1335	isochorismatase
ACICU_RS09650	COG1309	transcriptional regulator
ACICU_RS09680	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACICU_RS09690	COG1902	pentaerythritol trinitrate reductase activity
ACICU_RS09690	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_RS09695	COG1846	Transcriptional regulator
ACICU_RS09720	COG0753	catalase activity
ACICU_RS09735	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS09750	COG3162	membrane
ACICU_RS09760	COG3829	transcription factor binding
ACICU_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS09810	COG2186	Transcriptional regulator
ACICU_RS09820	COG0583	DNA-binding transcription factor activity
ACICU_RS09825	COG4948	Mandelate Racemase Muconate Lactonizing
ACICU_RS09830	COG4829	muconolactone delta-isomerase
ACICU_RS09840	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACICU_RS09845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_RS09850	COG0183	Belongs to the thiolase family
ACICU_RS09855	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACICU_RS09865	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS09875	COG3733	amine oxidase
ACICU_RS09885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_RS09895	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS09905	COG4638	Rieske (2fe-2S)
ACICU_RS09925	COG0154	amidase activity
ACICU_RS09935	COG2814	Major facilitator Superfamily
ACICU_RS09960	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS09965	COG0583	DNA-binding transcription factor activity
ACICU_RS09970	COG1414	Transcriptional regulator
ACICU_RS09985	COG2391	methyltransferase activity
ACICU_RS09995	COG4993	Dehydrogenase
ACICU_RS10000	COG3659	wide pore channel activity
ACICU_RS10005	COG3420	alginic acid biosynthetic process
ACICU_RS10010	COG0710	3-dehydroquinate dehydratase activity
ACICU_RS10015	COG3485	protocatechuate 3,4-dioxygenase
ACICU_RS10020	COG3485	protocatechuate 3,4-dioxygenase
ACICU_RS10025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACICU_RS10030	COG2271	Major facilitator Superfamily
ACICU_RS10035	COG0596	Alpha beta hydrolase
ACICU_RS10040	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACICU_RS10045	COG0183	Belongs to the thiolase family
ACICU_RS10050	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACICU_RS10065	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACICU_RS10070	COG2323	membrane
ACICU_RS10115	COG1902	pentaerythritol trinitrate reductase activity
ACICU_RS10115	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACICU_RS10140	COG0542	response to heat
ACICU_RS10175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACICU_RS10180	COG0569	domain protein
ACICU_RS10185	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACICU_RS10200	COG4774	siderophore transport
ACICU_RS10205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACICU_RS10215	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACICU_RS10240	COG1294	oxidase, subunit
ACICU_RS10245	COG4890	Cyd operon protein YbgT
ACICU_RS10260	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACICU_RS10270	COG0552	protein localization to endoplasmic reticulum
ACICU_RS10295	COG0517	IMP dehydrogenase activity
ACICU_RS10295	COG0516	GMP reductase activity
ACICU_RS10300	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACICU_RS10305	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACICU_RS10315	COG0583	DNA-binding transcription factor activity
ACICU_RS10320	COG0024	Methionine aminopeptidase
ACICU_RS10350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACICU_RS10350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACICU_RS10355	COG1105	Belongs to the carbohydrate kinase PfkB family
ACICU_RS10360	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACICU_RS10360	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACICU_RS10360	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACICU_RS10385	COG3300	MHYT domain
ACICU_RS10385	COG5001	Diguanylate cyclase
ACICU_RS10400	COG2135	peptidase activity
ACICU_RS10405	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_RS10420	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS10425	COG1113	amino acid transport
ACICU_RS10435	COG1522	sequence-specific DNA binding
ACICU_RS10460	COG1011	Hydrolase
ACICU_RS10465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACICU_RS10475	COG2137	regulation of response to DNA damage stimulus
ACICU_RS10485	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_RS10520	COG0575	Belongs to the CDS family
ACICU_RS10525	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACICU_RS10545	COG3852	Histidine kinase
ACICU_RS10550	COG2204	response regulator
ACICU_RS10605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACICU_RS10610	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACICU_RS10635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_RS10645	COG0303	'Molybdopterin
ACICU_RS10650	COG0315	cyclic pyranopterin monophosphate synthase activity
ACICU_RS10650	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACICU_RS10665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACICU_RS10670	COG0243	molybdopterin cofactor binding
ACICU_RS10680	COG0243	molybdopterin cofactor binding
ACICU_RS10685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_RS10690	COG2146	nitrite reductase [NAD(P)H] activity
ACICU_RS10690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_RS10700	COG0745	RESPONSE REGULATOR receiver
ACICU_RS10705	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_RS10705	COG1116	anion transmembrane transporter activity
ACICU_RS10720	COG0511	ligase activity, forming carbon-carbon bonds
ACICU_RS10735	COG2814	Major facilitator Superfamily
ACICU_RS10835	COG0592	DNA-directed DNA polymerase activity
ACICU_RS10875	COG2026	Addiction module toxin, RelE StbE family
ACICU_RS11070	COG1484	DNA-dependent DNA replication
ACICU_RS11155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACICU_RS11215	COG0069	glutamate synthase activity
ACICU_RS11235	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACICU_RS11245	COG1454	alcohol dehydrogenase
ACICU_RS11250	COG0824	Thioesterase
ACICU_RS11260	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACICU_RS11275	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACICU_RS11280	COG2030	dehydratase
ACICU_RS11290	COG0183	Belongs to the thiolase family
ACICU_RS11305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACICU_RS11315	COG1522	sequence-specific DNA binding
ACICU_RS11320	COG3135	benzoate transporter
ACICU_RS11330	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACICU_RS11350	COG0589	response to stress
ACICU_RS11355	COG0488	(ABC) transporter
ACICU_RS11375	COG4773	Receptor
ACICU_RS11405	COG0668	transmembrane transport
ACICU_RS11415	COG1309	transcriptional regulator
ACICU_RS11430	COG1605	Chorismate mutase
ACICU_RS11440	COG4221	oxidoreductase activity
ACICU_RS11450	COG0308	aminopeptidase N
ACICU_RS11470	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ACICU_RS11480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACICU_RS11485	COG1454	alcohol dehydrogenase
ACICU_RS11505	COG0531	amino acid
ACICU_RS11510	COG4303	Ethanolamine ammonia lyase large subunit
ACICU_RS11515	COG4302	ethanolamine ammonia-lyase activity
ACICU_RS11520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACICU_RS11520	COG0519	Catalyzes the synthesis of GMP from XMP
ACICU_RS11525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACICU_RS11535	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACICU_RS11550	COG0697	spore germination
ACICU_RS11555	COG1923	regulation of RNA biosynthetic process
ACICU_RS11565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACICU_RS11570	COG0802	atpase or kinase
ACICU_RS11590	COG1187	pseudouridine synthase activity
ACICU_RS11620	COG2814	Major facilitator Superfamily
ACICU_RS11625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACICU_RS11650	COG0729	surface antigen
ACICU_RS11670	COG0174	glutamine synthetase
ACICU_RS11675	COG0745	RESPONSE REGULATOR receiver
ACICU_RS11680	COG2205	protein histidine kinase activity
ACICU_RS11690	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACICU_RS11695	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACICU_RS11720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_RS11725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_RS11730	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS11745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACICU_RS11750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACICU_RS11770	COG0583	DNA-binding transcription factor activity
ACICU_RS11785	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACICU_RS11795	COG3658	cytochrome
ACICU_RS11800	COG1215	transferase activity, transferring glycosyl groups
ACICU_RS11805	COG0726	polysaccharide deacetylase
ACICU_RS11805	COG1649	PFAM Uncharacterised BCR, COG1649
ACICU_RS11830	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACICU_RS11835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACICU_RS11845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACICU_RS11870	COG0305	Participates in initiation and elongation during chromosome replication
ACICU_RS11875	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACICU_RS11885	COG1305	Transglutaminase-like
ACICU_RS11895	COG2308	Evidence 4 Homologs of previously reported genes of
ACICU_RS11925	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACICU_RS11930	COG0138	bifunctional purine biosynthesis protein purh
ACICU_RS11935	COG0151	Belongs to the GarS family
ACICU_RS11940	COG1464	Belongs to the NlpA lipoprotein family
ACICU_RS11945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACICU_RS11950	COG2011	ABC-type metal ion transport system permease component
ACICU_RS11955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_RS11965	COG1301	dicarboxylic acid transport
ACICU_RS11995	COG1794	racemase activity, acting on amino acids and derivatives
ACICU_RS12005	COG3008	intermembrane lipid transfer
ACICU_RS12005	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACICU_RS12010	COG2995	paraquat-inducible protein a
ACICU_RS12020	COG2985	domain, Protein
ACICU_RS12045	COG0477	Major facilitator Superfamily
ACICU_RS12050	COG0477	Major facilitator Superfamily
ACICU_RS12085	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS12105	COG2186	Transcriptional regulator
ACICU_RS12115	COG0786	glutamate:sodium symporter activity
ACICU_RS12120	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACICU_RS12145	COG3111	PFAM Bacterial OB fold (BOF) protein
ACICU_RS12245	COG1610	YqeY-like protein
ACICU_RS12250	COG4783	chaperone-mediated protein folding
ACICU_RS12275	COG1286	toxin biosynthetic process
ACICU_RS12305	COG0778	Nitroreductase
ACICU_RS12315	COG0513	Belongs to the DEAD box helicase family
ACICU_RS12335	COG2363	Small membrane protein
ACICU_RS12365	COG1234	tRNA 3'-trailer cleavage
ACICU_RS12370	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACICU_RS12380	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACICU_RS12390	COG2819	hydrolase of the alpha beta superfamily
ACICU_RS12395	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS12400	COG1301	dicarboxylic acid transport
ACICU_RS12405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACICU_RS12410	COG3139	Protein of unknown function (DUF1315)
ACICU_RS12415	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACICU_RS12420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACICU_RS12430	COG0494	nUDIX hydrolase
ACICU_RS12440	COG0642	Histidine kinase
ACICU_RS12455	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACICU_RS12465	COG1720	tRNA m6t6A37 methyltransferase activity
ACICU_RS12480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_RS12485	COG0826	peptidase U32
ACICU_RS12490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACICU_RS12500	COG4598	ABC transporter
ACICU_RS12505	COG4160	amino acid transport
ACICU_RS12510	COG4215	(ABC) transporter
ACICU_RS12525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS12570	COG1131	(ABC) transporter
ACICU_RS12575	COG0842	Transport permease protein
ACICU_RS12590	COG0772	Belongs to the SEDS family
ACICU_RS12595	COG2951	lytic endotransglycosylase activity
ACICU_RS12620	COG2207	Transcriptional regulator
ACICU_RS12635	COG0052	Belongs to the universal ribosomal protein uS2 family
ACICU_RS12640	COG0024	Methionine aminopeptidase
ACICU_RS12650	COG2223	nitrite transmembrane transporter activity
ACICU_RS12665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_RS12670	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACICU_RS12675	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS12690	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACICU_RS12695	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACICU_RS12700	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACICU_RS12720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACICU_RS12725	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACICU_RS12730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACICU_RS12765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACICU_RS12775	COG0174	glutamine synthetase
ACICU_RS12790	COG0512	Glutamine amidotransferase of anthranilate synthase
ACICU_RS12795	COG0308	aminopeptidase N
ACICU_RS12825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACICU_RS12835	COG0302	gtp cyclohydrolase
ACICU_RS12840	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS12860	COG3739	integral membrane protein
ACICU_RS12875	COG1169	isochorismate synthase
ACICU_RS12885	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACICU_RS12890	COG1132	(ABC) transporter
ACICU_RS12895	COG1132	(ABC) transporter
ACICU_RS12910	COG3433	isochorismatase activity
ACICU_RS12910	COG1535	isochorismatase
ACICU_RS12915	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACICU_RS12920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_RS12930	COG4774	siderophore transport
ACICU_RS12935	COG4607	ABC-type enterochelin transport system periplasmic component
ACICU_RS12940	COG4604	ABC transporter, ATP-binding protein
ACICU_RS12945	COG4605	iron ion homeostasis
ACICU_RS12950	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACICU_RS12955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_RS12970	COG2964	Protein conserved in bacteria
ACICU_RS12980	COG1741	Belongs to the pirin family
ACICU_RS12995	COG1309	transcriptional regulator
ACICU_RS13005	COG4948	Mandelate Racemase Muconate Lactonizing
ACICU_RS13010	COG2814	Major facilitator Superfamily
ACICU_RS13045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACICU_RS13045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ACICU_RS13050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_RS13055	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS13065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_RS13070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_RS13075	COG0583	DNA-binding transcription factor activity
ACICU_RS13080	COG1113	amino acid transport
ACICU_RS13100	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACICU_RS13100	COG2508	Transcriptional regulator
ACICU_RS13130	COG2879	small protein
ACICU_RS13135	COG1966	Carbon starvation protein
ACICU_RS13185	COG0583	DNA-binding transcription factor activity
ACICU_RS13210	COG1686	Belongs to the peptidase S11 family
ACICU_RS13215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACICU_RS13250	COG0616	signal peptide processing
ACICU_RS13255	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACICU_RS13265	COG0573	inorganic phosphate transmembrane transporter activity
ACICU_RS13270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACICU_RS13275	COG1113	amino acid transport
ACICU_RS13280	COG3961	Belongs to the TPP enzyme family
ACICU_RS13285	COG1522	sequence-specific DNA binding
ACICU_RS13295	COG0076	glutamate decarboxylase activity
ACICU_RS13300	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACICU_RS13310	COG1309	transcriptional regulator
ACICU_RS13325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_RS13360	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_RS13385	COG0612	Peptidase, M16
ACICU_RS13395	COG1823	symporter activity
ACICU_RS13400	COG0583	DNA-binding transcription factor activity
ACICU_RS13405	COG0477	Major facilitator Superfamily
ACICU_RS13425	COG1187	pseudouridine synthase activity
ACICU_RS13440	COG1686	Belongs to the peptidase S11 family
ACICU_RS13445	COG1252	NADH dehydrogenase
ACICU_RS13455	COG0415	Belongs to the DNA photolyase family
ACICU_RS13470	COG1215	transferase activity, transferring glycosyl groups
ACICU_RS13500	COG2070	2-Nitropropane dioxygenase
ACICU_RS13690	COG5410	chromosome segregation
ACICU_RS13885	COG0556	nucleotide-excision repair
ACICU_RS13905	COG0436	Aminotransferase
ACICU_RS13930	COG4221	oxidoreductase activity
ACICU_RS13940	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACICU_RS13945	COG1381	Involved in DNA repair and RecF pathway recombination
ACICU_RS13955	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACICU_RS13970	COG0681	Belongs to the peptidase S26 family
ACICU_RS13985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACICU_RS14005	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACICU_RS14010	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACICU_RS14015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACICU_RS14025	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACICU_RS14030	COG4208	sulfate ABC transporter
ACICU_RS14035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACICU_RS14040	COG0583	DNA-binding transcription factor activity
ACICU_RS14045	COG4625	pathogenesis
ACICU_RS14060	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACICU_RS14075	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACICU_RS14085	COG1051	belongs to the nudix hydrolase family
ACICU_RS14085	COG1056	cytidyltransferase-related domain
ACICU_RS14090	COG1024	Enoyl-CoA hydratase
ACICU_RS14105	COG2814	Major facilitator Superfamily
ACICU_RS14110	COG0047	phosphoribosylformylglycinamidine synthase activity
ACICU_RS14110	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACICU_RS14130	COG1473	amidohydrolase
ACICU_RS14135	COG0824	Thioesterase
ACICU_RS14155	COG0823	Involved in the tonB-independent uptake of proteins
ACICU_RS14175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACICU_RS14210	COG0628	permease
ACICU_RS14220	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACICU_RS14225	COG0596	Alpha beta hydrolase
ACICU_RS14230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACICU_RS14230	COG0616	signal peptide processing
ACICU_RS14240	COG2333	competence protein COMEC
ACICU_RS14240	COG0658	competence protein
ACICU_RS14245	COG1136	(ABC) transporter
ACICU_RS14250	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACICU_RS14280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS14300	COG0463	Glycosyl transferase, family 2
ACICU_RS14330	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACICU_RS14345	COG0019	diaminopimelate decarboxylase activity
ACICU_RS14355	COG1113	amino acid transport
ACICU_RS14370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACICU_RS14380	COG3339	Conserved Protein
ACICU_RS14385	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACICU_RS14390	COG0243	molybdopterin cofactor binding
ACICU_RS14395	COG1929	Belongs to the glycerate kinase type-1 family
ACICU_RS14410	COG0778	Nitroreductase
ACICU_RS14435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_RS14450	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACICU_RS14470	COG0741	lytic transglycosylase activity
ACICU_RS14490	COG0584	glycerophosphoryl diester phosphodiesterase
ACICU_RS14495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACICU_RS14520	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACICU_RS14525	COG1597	lipid kinase activity
ACICU_RS14540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACICU_RS14545	COG0477	Major facilitator Superfamily
ACICU_RS14595	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACICU_RS14600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACICU_RS14625	COG0505	Belongs to the CarA family
ACICU_RS14645	COG0589	response to stress
ACICU_RS14660	COG2843	Capsule synthesis protein
ACICU_RS14705	COG2321	neutral zinc metallopeptidase
ACICU_RS14710	COG2354	Protein conserved in bacteria
ACICU_RS14730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACICU_RS14745	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACICU_RS14750	COG1053	succinate dehydrogenase
ACICU_RS14755	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACICU_RS14760	COG2009	succinate dehydrogenase
ACICU_RS14785	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS14810	COG2921	Belongs to the UPF0250 family
ACICU_RS14815	COG0321	lipoyl(octanoyl) transferase activity
ACICU_RS14830	COG0531	amino acid
ACICU_RS14840	COG1733	regulation of RNA biosynthetic process
ACICU_RS14845	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACICU_RS14850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACICU_RS14850	COG1648	precorrin-2 dehydrogenase activity
ACICU_RS14865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACICU_RS14895	COG0671	phosphoesterase, PA-phosphatase related
ACICU_RS14900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS14910	COG1538	Outer membrane efflux protein
ACICU_RS14915	COG0393	Putative heavy-metal-binding
ACICU_RS14920	COG0393	Putative heavy-metal-binding
ACICU_RS14930	COG1028	Short-chain dehydrogenase reductase Sdr
ACICU_RS14940	COG0525	valine-tRNA ligase activity
ACICU_RS14960	COG0583	DNA-binding transcription factor activity
ACICU_RS14965	COG0004	ammonium transporteR
ACICU_RS14975	COG0642	Histidine kinase
ACICU_RS14980	COG0745	RESPONSE REGULATOR receiver
ACICU_RS14985	COG2194	sulfuric ester hydrolase activity
ACICU_RS15005	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACICU_RS15020	COG2315	Protein conserved in bacteria
ACICU_RS15025	COG0142	geranyltranstransferase activity
ACICU_RS15030	COG2828	Protein conserved in bacteria
ACICU_RS15035	COG1113	amino acid transport
ACICU_RS15055	COG2207	Transcriptional regulator
ACICU_RS15080	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_RS15090	COG0560	Phosphoserine phosphatase
ACICU_RS15100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACICU_RS15110	COG1530	ribonuclease E activity
ACICU_RS15115	COG0424	maF-like protein
ACICU_RS15120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACICU_RS15125	COG1792	Involved in formation and maintenance of cell shape
ACICU_RS15130	COG1077	Cell shape determining protein MreB Mrl
ACICU_RS15135	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACICU_RS15145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACICU_RS15175	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACICU_RS15180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACICU_RS15185	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACICU_RS15190	COG1115	amino acid carrier protein
ACICU_RS15205	COG2814	Major facilitator Superfamily
ACICU_RS15210	COG1289	transmembrane transporter activity
ACICU_RS15220	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACICU_RS15235	COG1376	ErfK ybiS ycfS ynhG family protein
ACICU_RS15240	COG2832	Protein of unknown function (DUF454)
ACICU_RS15250	COG5510	response to toxic substance
ACICU_RS15270	COG0840	transmembrane signaling receptor activity
ACICU_RS15310	COG3422	double-strand break repair
ACICU_RS15315	COG2824	Alkylphosphonate utilization operon protein PhnA
ACICU_RS15320	COG3189	MarR family transcriptional regulator
ACICU_RS15330	COG0354	folic acid binding
ACICU_RS15335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACICU_RS15345	COG0679	Auxin Efflux Carrier
ACICU_RS15350	COG1902	pentaerythritol trinitrate reductase activity
ACICU_RS15355	COG4772	TonB-dependent receptor
ACICU_RS15360	COG2094	Belongs to the DNA glycosylase MPG family
ACICU_RS15385	COG1217	gtp-binding protein TYPA
ACICU_RS15390	COG2233	PERMEase
ACICU_RS15400	COG0833	amino acid
ACICU_RS15405	COG1690	Belongs to the RtcB family
ACICU_RS15415	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACICU_RS15415	COG2885	chlorophyll binding
ACICU_RS15425	COG0183	Belongs to the thiolase family
ACICU_RS15445	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACICU_RS15465	COG2207	Transcriptional regulator
ACICU_RS15470	COG0183	Belongs to the thiolase family
ACICU_RS15500	COG1272	protein, Hemolysin III
ACICU_RS15505	COG0477	Major facilitator Superfamily
ACICU_RS15520	COG0450	alkyl hydroperoxide reductase
ACICU_RS15540	COG0285	dihydrofolate synthase activity
ACICU_RS15590	COG2096	Adenosyltransferase
ACICU_RS15610	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACICU_RS15615	COG0745	RESPONSE REGULATOR receiver
ACICU_RS15620	COG2205	protein histidine kinase activity
ACICU_RS15630	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS15635	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS15645	COG0625	glutathione transferase activity
ACICU_RS15710	COG0438	transferase activity, transferring glycosyl groups
ACICU_RS15715	COG0463	Glycosyl transferase, family 2
ACICU_RS15720	COG0726	polysaccharide deacetylase
ACICU_RS15740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACICU_RS15745	COG2205	protein histidine kinase activity
ACICU_RS15790	COG1862	Preprotein translocase
ACICU_RS15800	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACICU_RS15805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACICU_RS15815	COG3781	membrane
ACICU_RS15820	COG0613	PHP domain protein
ACICU_RS15830	COG2350	Protein conserved in bacteria
ACICU_RS15860	COG1607	acyl-coa hydrolase
ACICU_RS15920	COG2199	diguanylate cyclase activity
ACICU_RS15930	COG1408	metallophosphoesterase
ACICU_RS15935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACICU_RS15945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACICU_RS15965	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACICU_RS15970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACICU_RS15985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACICU_RS15995	COG2969	positive regulation of protein catabolic process
ACICU_RS16015	COG2826	transposase and inactivated derivatives, IS30 family
ACICU_RS16020	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS16025	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACICU_RS16040	COG1309	transcriptional regulator
ACICU_RS16045	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS16090	COG1183	phosphatidylcholine synthase activity
ACICU_RS16095	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACICU_RS16125	COG0741	lytic transglycosylase activity
ACICU_RS16125	COG0739	heme binding
ACICU_RS16125	COG1196	nuclear chromosome segregation
ACICU_RS16135	COG1702	phosphate starvation-inducible protein PhoH
ACICU_RS16170	COG1295	ribonuclease BN
ACICU_RS16175	COG0697	spore germination
ACICU_RS16180	COG2169	Transcriptional regulator
ACICU_RS16185	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACICU_RS16230	COG0557	exoribonuclease II activity
ACICU_RS16235	COG0339	signal peptide processing
ACICU_RS16240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACICU_RS16270	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACICU_RS16275	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS16430	COG0626	cystathionine gamma-synthase activity
ACICU_RS16435	COG0433	COG0433 Predicted ATPase
ACICU_RS16440	COG1017	nitric oxide dioxygenase activity
ACICU_RS16440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACICU_RS16445	COG1959	2 iron, 2 sulfur cluster binding
ACICU_RS16460	COG1301	dicarboxylic acid transport
ACICU_RS16465	COG1946	Acyl-CoA thioesterase
ACICU_RS16485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACICU_RS16490	COG1040	competence protein
ACICU_RS16495	COG0494	nUDIX hydrolase
ACICU_RS16505	COG0598	Magnesium transport protein CorA
ACICU_RS16515	COG2854	intermembrane phospholipid transfer
ACICU_RS16525	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACICU_RS16530	COG1127	ABC transporter
ACICU_RS16540	COG0513	Belongs to the DEAD box helicase family
ACICU_RS16560	COG0408	coproporphyrinogen oxidase activity
ACICU_RS16575	COG1960	acyl-CoA dehydrogenase activity
ACICU_RS16585	COG1983	PspC domain protein
ACICU_RS16590	COG0517	IMP dehydrogenase activity
ACICU_RS16635	COG0583	DNA-binding transcription factor activity
ACICU_RS16675	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS16685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACICU_RS16690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACICU_RS16695	COG0833	amino acid
ACICU_RS16725	COG1192	Involved in chromosome partitioning
ACICU_RS16730	COG0628	permease
ACICU_RS16740	COG1289	transmembrane transporter activity
ACICU_RS16755	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_RS16760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACICU_RS16770	COG0277	FAD linked oxidase domain protein
ACICU_RS16775	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACICU_RS16800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACICU_RS16805	COG5380	lipid catabolic process
ACICU_RS16825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACICU_RS16875	COG0194	GDP metabolic process
ACICU_RS16885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACICU_RS16905	COG3307	-O-antigen
ACICU_RS16925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACICU_RS16930	COG1704	LemA family
ACICU_RS16940	COG0493	'glutamate synthase
ACICU_RS16945	COG0069	glutamate synthase activity
ACICU_RS16945	COG0070	glutamate synthase
ACICU_RS16945	COG0067	glutamate synthase
ACICU_RS16995	COG2226	methyltransferase
ACICU_RS17010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACICU_RS17015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACICU_RS17060	COG0833	amino acid
ACICU_RS17125	COG0488	(ABC) transporter
ACICU_RS17130	COG2873	o-acetylhomoserine
ACICU_RS17135	COG4221	oxidoreductase activity
ACICU_RS17140	COG0659	secondary active sulfate transmembrane transporter activity
ACICU_RS17160	COG0427	acetyl-CoA hydrolase
ACICU_RS17190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACICU_RS17230	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACICU_RS17285	COG2207	Transcriptional regulator
ACICU_RS17290	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACICU_RS17305	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACICU_RS17310	COG1733	regulation of RNA biosynthetic process
ACICU_RS17330	COG1733	regulation of RNA biosynthetic process
ACICU_RS17350	COG0667	Aldo Keto reductase
ACICU_RS17375	COG0583	DNA-binding transcription factor activity
ACICU_RS17380	COG2814	Major facilitator Superfamily
ACICU_RS17410	COG1335	isochorismatase
ACICU_RS17420	COG1012	belongs to the aldehyde dehydrogenase family
ACICU_RS17425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACICU_RS17435	COG1113	amino acid transport
ACICU_RS17445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACICU_RS17460	COG2814	Major facilitator Superfamily
ACICU_RS17470	COG0351	phosphomethylpyrimidine kinase
ACICU_RS17470	COG0352	thiamine-phosphate diphosphorylase activity
ACICU_RS17470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACICU_RS17490	COG1309	transcriptional regulator
ACICU_RS17495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACICU_RS17510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACICU_RS17520	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACICU_RS17530	COG0784	Response regulator, receiver
ACICU_RS17530	COG2198	Histidine kinase
ACICU_RS17530	COG2205	protein histidine kinase activity
ACICU_RS17555	COG1522	sequence-specific DNA binding
ACICU_RS17560	COG1335	isochorismatase
ACICU_RS17565	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACICU_RS17575	COG0668	transmembrane transport
ACICU_RS17580	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACICU_RS17585	COG1519	Transferase
ACICU_RS17590	COG1902	pentaerythritol trinitrate reductase activity
ACICU_RS17610	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACICU_RS17635	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACICU_RS17635	COG0426	domain, Protein
ACICU_RS17640	COG4774	siderophore transport
ACICU_RS17645	COG2119	membrane
ACICU_RS17655	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACICU_RS17665	COG4942	peptidase
ACICU_RS17680	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACICU_RS17690	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACICU_RS17710	COG0189	ligase activity
ACICU_RS17730	COG0708	Exodeoxyribonuclease III
ACICU_RS17735	COG1393	Belongs to the ArsC family
ACICU_RS17750	COG3706	GGDEF domain
ACICU_RS17790	COG2233	PERMEase
ACICU_RS17800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACICU_RS17810	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACICU_RS17820	COG3150	esterase
ACICU_RS17845	COG3179	chitinase
ACICU_RS17860	COG2918	glutathione biosynthetic process
ACICU_RS17875	COG2733	membrane
ACICU_RS17880	COG0436	Aminotransferase
ACICU_RS17885	COG0534	Mate efflux family protein
ACICU_RS17945	COG0753	catalase activity
ACICU_RS17990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACICU_RS17995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACICU_RS18005	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACICU_RS18010	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACICU_RS18015	COG0546	phosphoglycolate phosphatase activity
ACICU_RS18025	COG0010	Belongs to the arginase family
ACICU_RS18055	COG2188	Transcriptional regulator
ACICU_RS18065	COG0523	cobalamin synthesis protein
ACICU_RS18075	COG1113	amino acid transport
ACICU_RS18085	COG0625	glutathione transferase activity
ACICU_RS18105	COG1683	Conserved Protein
ACICU_RS18110	COG0534	Mate efflux family protein
ACICU_RS18115	COG0385	Bile acid
ACICU_RS18120	COG1335	isochorismatase
ACICU_RS18125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACICU_RS18145	COG2116	formate transmembrane transporter activity
ACICU_RS18150	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACICU_RS18155	COG2133	pyrroloquinoline quinone binding
ACICU_RS18160	COG2983	Belongs to the UPF0260 family
ACICU_RS18180	COG1194	a g-specific adenine glycosylase
ACICU_RS18195	COG2818	Glycosylase
ACICU_RS18200	COG1064	alcohol dehydrogenase
ACICU_RS18205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACICU_RS18215	COG0583	DNA-binding transcription factor activity
ACICU_RS18220	COG0656	L-ascorbic acid biosynthetic process
ACICU_RS18225	COG2814	Major facilitator Superfamily
ACICU_RS18260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACICU_RS18275	COG2233	PERMEase
ACICU_RS18315	COG0733	neurotransmitter:sodium symporter activity
ACICU_RS18355	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACICU_RS18360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACICU_RS18365	COG0596	Alpha beta hydrolase
ACICU_RS18390	COG0488	(ABC) transporter
ACICU_RS18395	COG0586	Pfam SNARE associated Golgi protein
ACICU_RS19005	COG0546	phosphoglycolate phosphatase activity