locus-tag	class	description
DMO12_RS00010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DMO12_RS00015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DMO12_RS00020	COG0596	Alpha beta hydrolase
DMO12_RS00045	COG0488	(ABC) transporter
DMO12_RS00050	COG0586	Pfam SNARE associated Golgi protein
DMO12_RS00060	COG0187	DNA topoisomerase II activity
DMO12_RS00070	COG0592	DNA-directed DNA polymerase activity
DMO12_RS00095	COG0706	membrane insertase activity
DMO12_RS00110	COG1230	cation diffusion facilitator family transporter
DMO12_RS00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMO12_RS00130	COG0402	S-adenosylhomocysteine deaminase activity
DMO12_RS00140	COG0754	glutathionylspermidine amidase activity
DMO12_RS00155	COG0861	Integral membrane protein TerC family
DMO12_RS00160	COG0671	phosphoesterase, PA-phosphatase related
DMO12_RS00170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DMO12_RS00190	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DMO12_RS00195	COG2951	lytic endotransglycosylase activity
DMO12_RS00245	COG0657	acetylesterase activity
DMO12_RS00250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DMO12_RS00290	COG1047	Peptidyl-prolyl cis-trans
DMO12_RS00300	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DMO12_RS00305	COG0196	riboflavin kinase activity
DMO12_RS00315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DMO12_RS00320	COG1309	transcriptional regulator
DMO12_RS00325	COG1116	anion transmembrane transporter activity
DMO12_RS00330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMO12_RS00335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMO12_RS00340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMO12_RS00345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMO12_RS00365	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS00370	COG0546	phosphoglycolate phosphatase activity
DMO12_RS00425	COG3023	N-Acetylmuramoyl-L-alanine amidase
DMO12_RS00430	COG0728	peptidoglycan biosynthetic process
DMO12_RS00455	COG1596	polysaccharide export
DMO12_RS00460	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DMO12_RS00465	COG1086	Polysaccharide biosynthesis protein
DMO12_RS00470	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DMO12_RS00475	COG1083	cytidylyl-transferase
DMO12_RS00490	COG2089	acid synthase
DMO12_RS00520	COG1216	Glycosyl transferase, family 2
DMO12_RS00525	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DMO12_RS00530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DMO12_RS00545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMO12_RS00550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMO12_RS00560	COG2186	Transcriptional regulator
DMO12_RS00570	COG0277	FAD linked oxidase domain protein
DMO12_RS00575	COG1448	Aminotransferase
DMO12_RS00580	COG1802	Transcriptional regulator
DMO12_RS00595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DMO12_RS00685	COG0564	pseudouridine synthase activity
DMO12_RS00725	COG0251	oxidation-reduction process
DMO12_RS00730	COG1113	amino acid transport
DMO12_RS00735	COG1113	amino acid transport
DMO12_RS00755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMO12_RS00760	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS00765	COG1024	Enoyl-CoA hydratase
DMO12_RS00770	COG1024	Enoyl-CoA hydratase
DMO12_RS00775	COG0477	Major facilitator Superfamily
DMO12_RS00780	COG3916	Acyl-homoserine-lactone synthase
DMO12_RS00790	COG2197	response regulator
DMO12_RS00800	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS00805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DMO12_RS00805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMO12_RS00805	COG3321	synthase
DMO12_RS00805	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DMO12_RS00840	COG0271	Belongs to the BolA IbaG family
DMO12_RS00850	COG1192	Involved in chromosome partitioning
DMO12_RS00865	COG0586	Pfam SNARE associated Golgi protein
DMO12_RS00870	COG2259	Doxx family
DMO12_RS00875	COG4399	Belongs to the UPF0754 family
DMO12_RS00880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMO12_RS00880	COG0519	Catalyzes the synthesis of GMP from XMP
DMO12_RS00925	COG0281	malic enzyme
DMO12_RS00930	COG2837	iron assimilation
DMO12_RS00935	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS00940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DMO12_RS00945	COG1121	(ABC) transporter
DMO12_RS01015	COG0386	Belongs to the glutathione peroxidase family
DMO12_RS01030	COG1309	transcriptional regulator
DMO12_RS01035	COG0697	spore germination
DMO12_RS01045	COG0758	DNA mediated transformation
DMO12_RS01080	COG1309	transcriptional regulator
DMO12_RS01115	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DMO12_RS01125	COG0655	NAD(P)H dehydrogenase (quinone) activity
DMO12_RS01160	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DMO12_RS01170	COG2814	Major facilitator Superfamily
DMO12_RS01180	COG1253	flavin adenine dinucleotide binding
DMO12_RS01185	COG3012	SEC-C Motif Domain Protein
DMO12_RS01190	COG2860	membrane
DMO12_RS01195	COG0477	Major facilitator Superfamily
DMO12_RS01205	COG0318	PFAM AMP-dependent synthetase and ligase
DMO12_RS01220	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DMO12_RS01310	COG0789	Transcriptional regulator
DMO12_RS01340	COG0659	secondary active sulfate transmembrane transporter activity
DMO12_RS01350	COG0606	chelatase, subunit chli
DMO12_RS01360	COG0347	Belongs to the P(II) protein family
DMO12_RS01365	COG0004	ammonium transporteR
DMO12_RS01375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMO12_RS01375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DMO12_RS01415	COG0795	lipopolysaccharide-transporting ATPase activity
DMO12_RS01420	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DMO12_RS01425	COG0793	Belongs to the peptidase S41A family
DMO12_RS01440	COG2197	response regulator
DMO12_RS01450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DMO12_RS01460	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMO12_RS01465	COG4974	Belongs to the 'phage' integrase family
DMO12_RS01490	COG0772	Belongs to the SEDS family
DMO12_RS01495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMO12_RS01500	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DMO12_RS01505	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMO12_RS01530	COG0697	spore germination
DMO12_RS01535	COG1538	Outer membrane efflux protein
DMO12_RS01555	COG3275	phosphorelay sensor kinase activity
DMO12_RS01565	COG0181	hydroxymethylbilane synthase activity
DMO12_RS01610	COG1716	ATPase activity
DMO12_RS01615	COG0546	phosphoglycolate phosphatase activity
DMO12_RS01710	COG0596	Alpha beta hydrolase
DMO12_RS01715	COG2056	Na+-H+ antiporter family
DMO12_RS01730	COG0326	Molecular chaperone. Has ATPase activity
DMO12_RS01745	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DMO12_RS01815	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DMO12_RS01820	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMO12_RS01820	COG2169	Transcriptional regulator
DMO12_RS01850	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DMO12_RS01860	COG0497	DNA recombination
DMO12_RS01875	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMO12_RS01885	COG0237	dephospho-CoA kinase activity
DMO12_RS01935	COG0195	Participates in both transcription termination and antitermination
DMO12_RS01950	COG1320	monovalent cation:proton antiporter activity
DMO12_RS01955	COG2212	antiporter activity
DMO12_RS01960	COG1863	multisubunit Na H antiporter MnhE subunit
DMO12_RS01965	COG0651	ATP synthesis coupled electron transport
DMO12_RS01970	COG1006	Multisubunit Na H antiporter MnhC subunit
DMO12_RS01975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMO12_RS01975	COG2111	Na H antiporter
DMO12_RS01990	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DMO12_RS01995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMO12_RS02010	COG2226	methyltransferase
DMO12_RS02030	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DMO12_RS02035	COG1074	ATP-dependent DNA helicase activity
DMO12_RS02040	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMO12_RS02045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMO12_RS02060	COG0598	Magnesium transport protein CorA
DMO12_RS02065	COG0789	Transcriptional regulator
DMO12_RS02070	COG0484	heat shock protein binding
DMO12_RS02080	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DMO12_RS02085	COG0475	glutathione-regulated potassium exporter activity
DMO12_RS02085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMO12_RS02090	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DMO12_RS02110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMO12_RS02120	COG4535	Mg2 and Co2 transporter CorC
DMO12_RS02125	COG0425	Belongs to the sulfur carrier protein TusA family
DMO12_RS02130	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DMO12_RS02130	COG0644	oxidoreductase
DMO12_RS02140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DMO12_RS02155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMO12_RS02160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DMO12_RS02200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DMO12_RS02215	COG0534	Mate efflux family protein
DMO12_RS02225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DMO12_RS02230	COG4221	oxidoreductase activity
DMO12_RS02235	COG0583	DNA-binding transcription factor activity
DMO12_RS02250	COG0318	PFAM AMP-dependent synthetase and ligase
DMO12_RS02255	COG1530	ribonuclease E activity
DMO12_RS02270	COG0546	phosphoglycolate phosphatase activity
DMO12_RS02275	COG2378	regulation of single-species biofilm formation
DMO12_RS02280	COG0625	glutathione transferase activity
DMO12_RS02290	COG0583	DNA-binding transcription factor activity
DMO12_RS02355	COG0473	3-isopropylmalate dehydrogenase activity
DMO12_RS02410	COG1301	dicarboxylic acid transport
DMO12_RS02420	COG1560	Kdo2-lipid A biosynthetic process
DMO12_RS02425	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS02430	COG0488	(ABC) transporter
DMO12_RS02435	COG2900	Belongs to the SlyX family
DMO12_RS02445	COG1733	regulation of RNA biosynthetic process
DMO12_RS02470	COG0210	DNA helicase
DMO12_RS02475	COG0724	RNA recognition motif
DMO12_RS02495	COG4651	solute:proton antiporter activity
DMO12_RS02495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMO12_RS02520	COG0788	formyltetrahydrofolate deformylase activity
DMO12_RS02620	COG2813	Specifically methylates the guanine in position
DMO12_RS02620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMO12_RS02630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DMO12_RS02640	COG4774	siderophore transport
DMO12_RS02650	COG0740	serine-type endopeptidase activity
DMO12_RS02670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DMO12_RS02670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DMO12_RS02675	COG0280	phosphate acetyltransferase
DMO12_RS02675	COG0857	belongs to the CobB CobQ family
DMO12_RS02680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DMO12_RS02690	COG0800	Aldolase
DMO12_RS02700	COG3265	gluconokinase activity
DMO12_RS02705	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS02715	COG2267	carboxylic ester hydrolase activity
DMO12_RS02730	COG0793	Belongs to the peptidase S41A family
DMO12_RS02765	COG1426	Protein conserved in bacteria
DMO12_RS02810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DMO12_RS02820	COG0318	PFAM AMP-dependent synthetase and ligase
DMO12_RS02835	COG2986	histidine ammonia-lyase
DMO12_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS02880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DMO12_RS02900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DMO12_RS02910	COG1162	GTPase activity
DMO12_RS02915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DMO12_RS02930	COG1538	Outer membrane efflux protein
DMO12_RS02935	COG0577	efflux transmembrane transporter activity
DMO12_RS02935	COG1136	(ABC) transporter
DMO12_RS02940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS02965	COG0028	Belongs to the TPP enzyme family
DMO12_RS02970	COG0440	acetolactate synthase activity
DMO12_RS03005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DMO12_RS03020	COG0084	hydrolase, TatD family'
DMO12_RS03035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DMO12_RS03045	COG0583	DNA-binding transcription factor activity
DMO12_RS03055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMO12_RS03060	COG2814	Major facilitator Superfamily
DMO12_RS03070	COG0697	spore germination
DMO12_RS03100	COG3622	Belongs to the hyi family
DMO12_RS03105	COG2084	Dehydrogenase
DMO12_RS03110	COG1024	Enoyl-CoA hydratase
DMO12_RS03115	COG0784	Response regulator, receiver
DMO12_RS03115	COG2205	protein histidine kinase activity
DMO12_RS03115	COG5002	protein histidine kinase activity
DMO12_RS03135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMO12_RS03145	COG3956	TIGRFAM MazG family protein
DMO12_RS03150	COG1555	photosystem II stabilization
DMO12_RS03155	COG0617	tRNA 3'-terminal CCA addition
DMO12_RS03160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DMO12_RS03180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMO12_RS03185	COG3028	Belongs to the UPF0307 family
DMO12_RS03190	COG0318	PFAM AMP-dependent synthetase and ligase
DMO12_RS03210	COG0625	glutathione transferase activity
DMO12_RS03215	COG1238	metal cluster binding
DMO12_RS03255	COG0072	phenylalanine-tRNA ligase activity
DMO12_RS03285	COG0248	Ppx GppA phosphatase
DMO12_RS03295	COG0037	tRNA processing
DMO12_RS03335	COG1764	response to oxidative stress
DMO12_RS03340	COG1846	Transcriptional regulator
DMO12_RS03350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMO12_RS03410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DMO12_RS03415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DMO12_RS03420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DMO12_RS03430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DMO12_RS03480	COG1214	PFAM Peptidase M22, glycoprotease
DMO12_RS03505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DMO12_RS03510	COG0561	phosphatase activity
DMO12_RS03520	COG2132	Multicopper oxidase
DMO12_RS03525	COG3667	copper resistance
DMO12_RS03540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DMO12_RS03545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DMO12_RS03550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DMO12_RS03580	COG1063	alcohol dehydrogenase
DMO12_RS03585	COG0583	DNA-binding transcription factor activity
DMO12_RS03590	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS03595	COG2814	Major facilitator Superfamily
DMO12_RS03600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DMO12_RS03610	COG1053	succinate dehydrogenase
DMO12_RS03615	COG0583	DNA-binding transcription factor activity
DMO12_RS03635	COG0583	DNA-binding transcription factor activity
DMO12_RS03660	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS03665	COG0583	DNA-binding transcription factor activity
DMO12_RS03680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMO12_RS03710	COG0384	phenazine biosynthesis protein PhzF
DMO12_RS03720	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS03735	COG4993	Dehydrogenase
DMO12_RS03805	COG2205	protein histidine kinase activity
DMO12_RS03815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DMO12_RS03835	COG0745	RESPONSE REGULATOR receiver
DMO12_RS03875	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DMO12_RS03905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DMO12_RS03910	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DMO12_RS03930	COG0583	DNA-binding transcription factor activity
DMO12_RS03950	COG0668	transmembrane transport
DMO12_RS03960	COG2081	HI0933 family
DMO12_RS03965	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DMO12_RS03995	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMO12_RS03995	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DMO12_RS04005	COG0489	protein tyrosine kinase activity
DMO12_RS04065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DMO12_RS04075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DMO12_RS04090	COG0730	response to heat
DMO12_RS04100	COG1196	nuclear chromosome segregation
DMO12_RS04120	COG2223	nitrite transmembrane transporter activity
DMO12_RS04125	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DMO12_RS04130	COG1877	trehalose-phosphatase activity
DMO12_RS04135	COG2226	methyltransferase
DMO12_RS04135	COG0596	Alpha beta hydrolase
DMO12_RS04135	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMO12_RS04150	COG4106	trans-aconitate 2-methyltransferase activity
DMO12_RS04165	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DMO12_RS04170	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DMO12_RS04175	COG0009	L-threonylcarbamoyladenylate synthase
DMO12_RS04180	COG3101	peptidyl-lysine hydroxylation
DMO12_RS04185	COG1399	metal-binding, possibly nucleic acid-binding protein
DMO12_RS04210	COG1652	LysM domain
DMO12_RS04215	COG0352	thiamine-phosphate diphosphorylase activity
DMO12_RS04215	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DMO12_RS04215	COG0351	phosphomethylpyrimidine kinase
DMO12_RS04225	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DMO12_RS04255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMO12_RS04285	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DMO12_RS04300	COG0358	DNA primase activity
DMO12_RS04335	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMO12_RS04355	COG0583	DNA-binding transcription factor activity
DMO12_RS04360	COG0473	3-isopropylmalate dehydrogenase activity
DMO12_RS04370	COG0657	acetylesterase activity
DMO12_RS04380	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS04400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DMO12_RS04400	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DMO12_RS04415	COG1981	membrane
DMO12_RS04460	COG0456	acetyltransferase
DMO12_RS04470	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DMO12_RS04475	COG0492	ferredoxin-NADP+ reductase activity
DMO12_RS04480	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DMO12_RS04480	COG1674	ftsk spoiiie
DMO12_RS04485	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS04505	COG2894	cell division
DMO12_RS04520	COG0204	Acyl-transferase
DMO12_RS04525	COG2885	chlorophyll binding
DMO12_RS04530	COG0210	DNA helicase
DMO12_RS04540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DMO12_RS04555	COG0121	glutamine amidotransferase
DMO12_RS04580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DMO12_RS04585	COG0735	belongs to the Fur family
DMO12_RS04610	COG0420	3'-5' exonuclease activity
DMO12_RS04630	COG1090	epimerase
DMO12_RS04645	COG2050	protein possibly involved in aromatic compounds catabolism
DMO12_RS04660	COG2814	Major facilitator Superfamily
DMO12_RS04665	COG0405	Gamma-glutamyltransferase
DMO12_RS04705	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS04720	COG0477	Major facilitator Superfamily
DMO12_RS04725	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMO12_RS04735	COG1595	DNA-templated transcription, initiation
DMO12_RS04790	COG0531	amino acid
DMO12_RS04795	COG2040	homocysteine
DMO12_RS04820	COG1309	transcriptional regulator
DMO12_RS04825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMO12_RS04830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMO12_RS04840	COG1607	acyl-coa hydrolase
DMO12_RS04850	COG0523	cobalamin synthesis protein
DMO12_RS04860	COG4681	YaeQ
DMO12_RS04870	COG1649	PFAM Uncharacterised BCR, COG1649
DMO12_RS04870	COG0726	polysaccharide deacetylase
DMO12_RS04875	COG1215	transferase activity, transferring glycosyl groups
DMO12_RS04885	COG1024	Enoyl-CoA hydratase
DMO12_RS04900	COG1414	Transcriptional regulator
DMO12_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS04930	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMO12_RS04935	COG2271	Major facilitator Superfamily
DMO12_RS04945	COG2267	carboxylic ester hydrolase activity
DMO12_RS04950	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS04965	COG0028	Belongs to the TPP enzyme family
DMO12_RS04975	COG0477	Major facilitator Superfamily
DMO12_RS04980	COG0242	peptide deformylase activity
DMO12_RS04985	COG2066	Belongs to the glutaminase family
DMO12_RS04990	COG2207	Transcriptional regulator
DMO12_RS04995	COG2223	nitrite transmembrane transporter activity
DMO12_RS05015	COG0583	DNA-binding transcription factor activity
DMO12_RS05020	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS05025	COG2271	Major facilitator Superfamily
DMO12_RS05030	COG3959	Transketolase, thiamine diphosphate binding domain
DMO12_RS05035	COG3958	Transketolase
DMO12_RS05045	COG0306	phosphate transporter
DMO12_RS05065	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DMO12_RS05110	COG4181	ATPase activity
DMO12_RS05115	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DMO12_RS05140	COG0583	DNA-binding transcription factor activity
DMO12_RS05150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMO12_RS05155	COG1773	rubredoxin
DMO12_RS05205	COG2851	Citrate transporter
DMO12_RS05215	COG1253	flavin adenine dinucleotide binding
DMO12_RS05255	COG0804	urea catabolic process
DMO12_RS05265	COG0830	nickel cation binding
DMO12_RS05280	COG0742	ribosomal rna small subunit methyltransferase
DMO12_RS05285	COG0768	penicillin binding
DMO12_RS05310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DMO12_RS05315	COG2878	Part of a membrane complex involved in electron transport
DMO12_RS05320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMO12_RS05330	COG3384	dioxygenase
DMO12_RS05355	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DMO12_RS05735	COG2194	sulfuric ester hydrolase activity
DMO12_RS05770	COG0006	proline dipeptidase activity
DMO12_RS05775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMO12_RS05780	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMO12_RS05800	COG1279	arginine transmembrane transporter activity
DMO12_RS05805	COG0583	DNA-binding transcription factor activity
DMO12_RS05845	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DMO12_RS05850	COG1388	LysM domain
DMO12_RS05850	COG1388	LysM domain
DMO12_RS05850	COG0741	lytic transglycosylase activity
DMO12_RS05850	COG0741	lytic transglycosylase activity
DMO12_RS05860	COG4174	ABC transporter (Permease)
DMO12_RS05865	COG4239	(ABC) transporter, permease
DMO12_RS05870	COG4172	Belongs to the ABC transporter superfamily
DMO12_RS05890	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DMO12_RS05900	COG5001	Diguanylate cyclase
DMO12_RS05900	COG3706	GGDEF domain
DMO12_RS05900	COG2203	Gaf domain
DMO12_RS05900	COG4251	negative regulation of phosphorylation
DMO12_RS05910	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMO12_RS05910	COG1902	pentaerythritol trinitrate reductase activity
DMO12_RS05925	COG4269	membrane
DMO12_RS05950	COG3209	COG3209 Rhs family protein
DMO12_RS05995	COG1113	amino acid transport
DMO12_RS06005	COG0531	amino acid
DMO12_RS06025	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS06045	COG1113	amino acid transport
DMO12_RS06065	COG1309	transcriptional regulator
DMO12_RS06070	COG1741	Belongs to the pirin family
DMO12_RS06085	COG2072	flavoprotein involved in K transport
DMO12_RS06095	COG2252	PERMEase
DMO12_RS06100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DMO12_RS06105	COG3038	cytochrome b561
DMO12_RS06115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DMO12_RS06125	COG0527	aspartate kinase activity
DMO12_RS06135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DMO12_RS06145	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DMO12_RS06160	COG0667	Aldo Keto reductase
DMO12_RS06170	COG1765	OsmC-like protein
DMO12_RS06185	COG0542	response to heat
DMO12_RS06220	COG2885	chlorophyll binding
DMO12_RS06230	COG0625	glutathione transferase activity
DMO12_RS06235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DMO12_RS06255	COG3634	alkyl hydroperoxide reductase activity
DMO12_RS06265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DMO12_RS06275	COG0450	alkyl hydroperoxide reductase
DMO12_RS06280	COG1643	Atp-dependent helicase
DMO12_RS06295	COG2814	Major facilitator Superfamily
DMO12_RS06300	COG3135	benzoate transporter
DMO12_RS06305	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS06310	COG0633	Ferredoxin
DMO12_RS06310	COG0543	2 iron, 2 sulfur cluster binding
DMO12_RS06315	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DMO12_RS06320	COG4638	Rieske (2fe-2S)
DMO12_RS06325	COG0583	DNA-binding transcription factor activity
DMO12_RS06380	COG1570	exodeoxyribonuclease VII activity
DMO12_RS06415	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS06420	COG1278	Cold shock
DMO12_RS06460	COG2814	Major facilitator Superfamily
DMO12_RS06500	COG0517	IMP dehydrogenase activity
DMO12_RS06500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DMO12_RS06505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DMO12_RS06515	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DMO12_RS06520	COG1137	ATPase activity
DMO12_RS06525	COG1538	Outer membrane efflux protein
DMO12_RS06555	COG4122	O-methyltransferase activity
DMO12_RS06565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DMO12_RS06600	COG5006	permease, DMT superfamily
DMO12_RS06610	COG1560	Kdo2-lipid A biosynthetic process
DMO12_RS06625	COG2814	Major facilitator Superfamily
DMO12_RS06645	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMO12_RS06700	COG0583	DNA-binding transcription factor activity
DMO12_RS06705	COG1914	H( )-stimulated, divalent metal cation uptake system
DMO12_RS06725	COG4770	biotin carboxylase activity
DMO12_RS06730	COG0038	chloride channel
DMO12_RS06755	COG1309	transcriptional regulator
DMO12_RS06765	COG1063	alcohol dehydrogenase
DMO12_RS06780	COG0439	Biotin carboxylase
DMO12_RS06785	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMO12_RS06805	COG0864	Transcriptional regulator
DMO12_RS06815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMO12_RS06820	COG1116	anion transmembrane transporter activity
DMO12_RS06940	COG0590	tRNA wobble adenosine to inosine editing
DMO12_RS06945	COG2807	transmembrane transport
DMO12_RS06960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DMO12_RS06970	COG0789	Transcriptional regulator
DMO12_RS06985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMO12_RS07005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMO12_RS07015	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMO12_RS07030	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS07035	COG0531	amino acid
DMO12_RS07040	COG1760	l-serine dehydratase
DMO12_RS07045	COG2030	dehydratase
DMO12_RS07045	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS07050	COG3396	Phenylacetate-CoA oxygenase
DMO12_RS07055	COG3460	Phenylacetate-CoA oxygenase
DMO12_RS07060	COG3396	Phenylacetate-CoA oxygenase
DMO12_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
DMO12_RS07070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMO12_RS07075	COG1024	Enoyl-CoA hydratase
DMO12_RS07080	COG1024	Enoyl-CoA hydratase
DMO12_RS07085	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMO12_RS07090	COG0183	Belongs to the thiolase family
DMO12_RS07095	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DMO12_RS07100	COG3327	negative regulation of DNA-templated transcription, initiation
DMO12_RS07110	COG2050	protein possibly involved in aromatic compounds catabolism
DMO12_RS07150	COG0753	catalase activity
DMO12_RS07155	COG3038	cytochrome b561
DMO12_RS07175	COG2267	carboxylic ester hydrolase activity
DMO12_RS07180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMO12_RS07185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMO12_RS07190	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS07200	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DMO12_RS07210	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS07215	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMO12_RS07220	COG0583	DNA-binding transcription factor activity
DMO12_RS07230	COG1414	Transcriptional regulator
DMO12_RS07235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMO12_RS07245	COG1840	ABC-type Fe3 transport system, periplasmic component
DMO12_RS07250	COG3842	ATPase activity
DMO12_RS07265	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DMO12_RS07270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DMO12_RS07275	COG2814	Major facilitator Superfamily
DMO12_RS07280	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS07295	COG1024	Enoyl-CoA hydratase
DMO12_RS07305	COG2814	Major facilitator Superfamily
DMO12_RS07315	COG0183	Belongs to the thiolase family
DMO12_RS07320	COG1250	3-hydroxyacyl-CoA dehydrogenase
DMO12_RS07325	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS07330	COG1024	Enoyl-CoA hydratase
DMO12_RS07335	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS07340	COG2814	Major facilitator Superfamily
DMO12_RS07345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DMO12_RS07350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DMO12_RS07360	COG2814	Major facilitator Superfamily
DMO12_RS07370	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS07385	COG0583	DNA-binding transcription factor activity
DMO12_RS07395	COG4770	biotin carboxylase activity
DMO12_RS07400	COG1024	Enoyl-CoA hydratase
DMO12_RS07405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMO12_RS07410	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS07415	COG1309	transcriptional regulator
DMO12_RS07420	COG0318	PFAM AMP-dependent synthetase and ligase
DMO12_RS07440	COG0583	DNA-binding transcription factor activity
DMO12_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS07505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DMO12_RS07525	COG2205	protein histidine kinase activity
DMO12_RS07525	COG0784	Response regulator, receiver
DMO12_RS07545	COG0765	amino acid transport
DMO12_RS07550	COG0765	amino acid transport
DMO12_RS07555	COG1126	abc transporter atp-binding protein
DMO12_RS07560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMO12_RS07565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DMO12_RS07580	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS07590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DMO12_RS07595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMO12_RS07600	COG1045	serine acetyltransferase
DMO12_RS07615	COG0583	DNA-binding transcription factor activity
DMO12_RS07620	COG0625	glutathione transferase activity
DMO12_RS07625	COG0625	glutathione transferase activity
DMO12_RS07630	COG0583	DNA-binding transcription factor activity
DMO12_RS07640	COG1346	cytolysis
DMO12_RS07660	COG2814	Major facilitator Superfamily
DMO12_RS07670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DMO12_RS07675	COG3052	prosthetic group binding
DMO12_RS07695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DMO12_RS07715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMO12_RS07725	COG1294	oxidase, subunit
DMO12_RS07730	COG1271	oxidase subunit
DMO12_RS07755	COG0477	Major facilitator Superfamily
DMO12_RS07765	COG4521	taurine ABC transporter
DMO12_RS07770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DMO12_RS07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMO12_RS07780	COG2175	clavaminate synthase activity
DMO12_RS07790	COG1953	Uracil, thiamine, allantoin
DMO12_RS07800	COG0583	DNA-binding transcription factor activity
DMO12_RS07810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DMO12_RS07825	COG0640	Transcriptional regulator
DMO12_RS07830	COG0798	PFAM Bile acid sodium symporter
DMO12_RS07835	COG0583	DNA-binding transcription factor activity
DMO12_RS07850	COG3634	alkyl hydroperoxide reductase activity
DMO12_RS07890	COG0436	Aminotransferase
DMO12_RS07900	COG0386	Belongs to the glutathione peroxidase family
DMO12_RS07940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DMO12_RS07965	COG0012	GTP binding
DMO12_RS07970	COG2011	ABC-type metal ion transport system permease component
DMO12_RS07975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMO12_RS07985	COG1464	Belongs to the NlpA lipoprotein family
DMO12_RS08015	COG0765	amino acid transport
DMO12_RS08020	COG0765	amino acid transport
DMO12_RS08025	COG1126	abc transporter atp-binding protein
DMO12_RS08035	COG1522	sequence-specific DNA binding
DMO12_RS08050	COG1309	transcriptional regulator
DMO12_RS08070	COG0583	DNA-binding transcription factor activity
DMO12_RS08080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DMO12_RS08090	COG0697	spore germination
DMO12_RS08120	COG3121	Chaperone
DMO12_RS08125	COG3539	Fimbrial protein
DMO12_RS08150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DMO12_RS08150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DMO12_RS08195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DMO12_RS08205	COG2353	YceI-like domain
DMO12_RS08215	COG3698	Phosphodiester glycosidase
DMO12_RS08230	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DMO12_RS08235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DMO12_RS08235	COG0506	proline dehydrogenase activity
DMO12_RS08235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DMO12_RS08245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMO12_RS08250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DMO12_RS08270	COG1132	(ABC) transporter
DMO12_RS08275	COG3122	Protein conserved in bacteria
DMO12_RS08280	COG3619	membrane
DMO12_RS08290	COG0640	Transcriptional regulator
DMO12_RS08300	COG2850	peptidyl-arginine hydroxylation
DMO12_RS08305	COG0424	maF-like protein
DMO12_RS08325	COG0191	fructose-bisphosphate aldolase activity
DMO12_RS08330	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMO12_RS08345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DMO12_RS08355	COG1192	Involved in chromosome partitioning
DMO12_RS08360	COG1475	DNA binding
DMO12_RS08365	COG0811	peptide transport
DMO12_RS08375	COG1132	(ABC) transporter
DMO12_RS08380	COG1663	tetraacyldisaccharide 4'-kinase activity
DMO12_RS08400	COG0084	hydrolase, TatD family'
DMO12_RS08465	COG0776	regulation of translation
DMO12_RS08495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DMO12_RS08500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DMO12_RS08550	COG0339	signal peptide processing
DMO12_RS08560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DMO12_RS08595	COG0702	epimerase
DMO12_RS08600	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DMO12_RS08620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DMO12_RS08650	COG0316	Belongs to the HesB IscA family
DMO12_RS08655	COG0822	iron-sulfur transferase activity
DMO12_RS08680	COG0776	regulation of translation
DMO12_RS08685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DMO12_RS08690	COG2207	Transcriptional regulator
DMO12_RS08695	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMO12_RS08700	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS08705	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS08720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DMO12_RS08740	COG4264	IucA IucC family
DMO12_RS08745	COG4264	IucA IucC family
DMO12_RS08805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DMO12_RS08825	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DMO12_RS08830	COG0730	response to heat
DMO12_RS08850	COG4773	Receptor
DMO12_RS08855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMO12_RS08870	COG1131	(ABC) transporter
DMO12_RS08875	COG0842	Transport permease protein
DMO12_RS08880	COG0842	Transport permease protein
DMO12_RS08935	COG2226	methyltransferase
DMO12_RS08960	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DMO12_RS08995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMO12_RS09005	COG0133	tryptophan synthase activity
DMO12_RS09020	COG3706	GGDEF domain
DMO12_RS09035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMO12_RS09040	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DMO12_RS09045	COG0022	dehydrogenase e1 component
DMO12_RS09050	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMO12_RS09055	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMO12_RS09065	COG1063	alcohol dehydrogenase
DMO12_RS09070	COG3781	membrane
DMO12_RS09080	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMO12_RS09080	COG3453	Protein conserved in bacteria
DMO12_RS09090	COG0730	response to heat
DMO12_RS09105	COG3708	Transcriptional regulator
DMO12_RS09105	COG2207	Transcriptional regulator
DMO12_RS09110	COG1733	regulation of RNA biosynthetic process
DMO12_RS09115	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DMO12_RS09125	COG2188	Transcriptional regulator
DMO12_RS09140	COG4521	taurine ABC transporter
DMO12_RS09145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMO12_RS09165	COG0477	Major facilitator Superfamily
DMO12_RS09175	COG1027	Aspartate ammonia-lyase
DMO12_RS09190	COG0583	DNA-binding transcription factor activity
DMO12_RS09195	COG0583	DNA-binding transcription factor activity
DMO12_RS09200	COG0183	Belongs to the thiolase family
DMO12_RS09205	COG2031	fatty acid transporter
DMO12_RS09210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DMO12_RS09220	COG0583	DNA-binding transcription factor activity
DMO12_RS09230	COG2610	gluconate transmembrane transporter activity
DMO12_RS09235	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS09240	COG2207	Transcriptional regulator
DMO12_RS09255	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS09280	COG0543	2 iron, 2 sulfur cluster binding
DMO12_RS09280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMO12_RS09285	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DMO12_RS09290	COG4638	Rieske (2fe-2S)
DMO12_RS09300	COG0725	ABC transporter, periplasmic molybdate-binding protein
DMO12_RS09305	COG4149	molybdate abc transporter
DMO12_RS09310	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DMO12_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS09320	COG3433	isochorismatase activity
DMO12_RS09320	COG1535	isochorismatase
DMO12_RS09385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMO12_RS09400	COG0753	catalase activity
DMO12_RS09410	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DMO12_RS09435	COG3539	Fimbrial protein
DMO12_RS09455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMO12_RS09475	COG2072	flavoprotein involved in K transport
DMO12_RS09485	COG1538	Outer membrane efflux protein
DMO12_RS09490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DMO12_RS09495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS09500	COG0745	RESPONSE REGULATOR receiver
DMO12_RS09505	COG2205	protein histidine kinase activity
DMO12_RS09515	COG2207	Transcriptional regulator
DMO12_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS09585	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DMO12_RS09705	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DMO12_RS09725	COG1120	ATPase activity
DMO12_RS09730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMO12_RS09740	COG1064	alcohol dehydrogenase
DMO12_RS09755	COG2207	Transcriptional regulator
DMO12_RS09760	COG2084	Dehydrogenase
DMO12_RS09770	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DMO12_RS09775	COG0583	DNA-binding transcription factor activity
DMO12_RS09785	COG0129	dihydroxy-acid dehydratase activity
DMO12_RS09790	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS09805	COG1566	PFAM secretion protein HlyD family protein
DMO12_RS09825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DMO12_RS09855	COG0583	DNA-binding transcription factor activity
DMO12_RS09870	COG2188	Transcriptional regulator
DMO12_RS09900	COG3210	domain, Protein
DMO12_RS09905	COG2831	hemolysin activation secretion protein
DMO12_RS09920	COG1473	amidohydrolase
DMO12_RS09930	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DMO12_RS09930	COG0475	glutathione-regulated potassium exporter activity
DMO12_RS09940	COG0583	DNA-binding transcription factor activity
DMO12_RS09945	COG1335	isochorismatase
DMO12_RS09955	COG1309	transcriptional regulator
DMO12_RS09985	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DMO12_RS09995	COG1902	pentaerythritol trinitrate reductase activity
DMO12_RS09995	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMO12_RS10000	COG1846	Transcriptional regulator
DMO12_RS10025	COG0753	catalase activity
DMO12_RS10040	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS10055	COG3162	membrane
DMO12_RS10065	COG3829	transcription factor binding
DMO12_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS10075	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS10115	COG2186	Transcriptional regulator
DMO12_RS10125	COG0583	DNA-binding transcription factor activity
DMO12_RS10130	COG4948	Mandelate Racemase Muconate Lactonizing
DMO12_RS10135	COG4829	muconolactone delta-isomerase
DMO12_RS10145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DMO12_RS10150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DMO12_RS10155	COG0183	Belongs to the thiolase family
DMO12_RS10160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DMO12_RS10170	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS10180	COG3733	amine oxidase
DMO12_RS10190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMO12_RS10200	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS10210	COG4638	Rieske (2fe-2S)
DMO12_RS10230	COG0154	amidase activity
DMO12_RS10240	COG2814	Major facilitator Superfamily
DMO12_RS10265	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS10270	COG0583	DNA-binding transcription factor activity
DMO12_RS10275	COG1414	Transcriptional regulator
DMO12_RS10290	COG2391	methyltransferase activity
DMO12_RS10300	COG4993	Dehydrogenase
DMO12_RS10305	COG3659	wide pore channel activity
DMO12_RS10310	COG3420	alginic acid biosynthetic process
DMO12_RS10315	COG0710	3-dehydroquinate dehydratase activity
DMO12_RS10320	COG3485	protocatechuate 3,4-dioxygenase
DMO12_RS10325	COG3485	protocatechuate 3,4-dioxygenase
DMO12_RS10330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DMO12_RS10335	COG2271	Major facilitator Superfamily
DMO12_RS10340	COG0596	Alpha beta hydrolase
DMO12_RS10345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DMO12_RS10350	COG0183	Belongs to the thiolase family
DMO12_RS10355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DMO12_RS10360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DMO12_RS10370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DMO12_RS10375	COG2323	membrane
DMO12_RS10420	COG0446	pyridine nucleotide-disulphide oxidoreductase
DMO12_RS10420	COG1902	pentaerythritol trinitrate reductase activity
DMO12_RS10445	COG0542	response to heat
DMO12_RS10450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DMO12_RS10480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMO12_RS10485	COG0569	domain protein
DMO12_RS10490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DMO12_RS10505	COG4774	siderophore transport
DMO12_RS10510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DMO12_RS10520	COG1585	Membrane protein implicated in regulation of membrane protease activity
DMO12_RS10545	COG1294	oxidase, subunit
DMO12_RS10550	COG4890	Cyd operon protein YbgT
DMO12_RS10565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DMO12_RS10575	COG0552	protein localization to endoplasmic reticulum
DMO12_RS10600	COG0516	GMP reductase activity
DMO12_RS10600	COG0517	IMP dehydrogenase activity
DMO12_RS10605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMO12_RS10610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DMO12_RS10620	COG0583	DNA-binding transcription factor activity
DMO12_RS10625	COG0024	Methionine aminopeptidase
DMO12_RS10655	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DMO12_RS10655	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DMO12_RS10660	COG1105	Belongs to the carbohydrate kinase PfkB family
DMO12_RS10665	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DMO12_RS10665	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DMO12_RS10665	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DMO12_RS10685	COG5001	Diguanylate cyclase
DMO12_RS10685	COG3300	MHYT domain
DMO12_RS10700	COG2135	peptidase activity
DMO12_RS10705	COG0659	secondary active sulfate transmembrane transporter activity
DMO12_RS10720	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS10730	COG1113	amino acid transport
DMO12_RS10740	COG1522	sequence-specific DNA binding
DMO12_RS10765	COG1011	Hydrolase
DMO12_RS10770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DMO12_RS10780	COG2137	regulation of response to DNA damage stimulus
DMO12_RS10795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMO12_RS10830	COG0575	Belongs to the CDS family
DMO12_RS10835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DMO12_RS10860	COG3852	Histidine kinase
DMO12_RS10865	COG2204	response regulator
DMO12_RS10925	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DMO12_RS10930	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DMO12_RS10950	COG0697	spore germination
DMO12_RS10955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMO12_RS10965	COG0303	'Molybdopterin
DMO12_RS10970	COG0521	Mo-molybdopterin cofactor biosynthetic process
DMO12_RS10970	COG0315	cyclic pyranopterin monophosphate synthase activity
DMO12_RS10985	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DMO12_RS10990	COG0243	molybdopterin cofactor binding
DMO12_RS11000	COG0243	molybdopterin cofactor binding
DMO12_RS11005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMO12_RS11010	COG2146	nitrite reductase [NAD(P)H] activity
DMO12_RS11010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMO12_RS11020	COG0745	RESPONSE REGULATOR receiver
DMO12_RS11025	COG1116	anion transmembrane transporter activity
DMO12_RS11025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMO12_RS11045	COG0511	ligase activity, forming carbon-carbon bonds
DMO12_RS11060	COG2814	Major facilitator Superfamily
DMO12_RS11160	COG0592	DNA-directed DNA polymerase activity
DMO12_RS11200	COG2026	Addiction module toxin, RelE StbE family
DMO12_RS11400	COG1484	DNA-dependent DNA replication
DMO12_RS11485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DMO12_RS11545	COG0069	glutamate synthase activity
DMO12_RS11565	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DMO12_RS11575	COG1454	alcohol dehydrogenase
DMO12_RS11580	COG0824	Thioesterase
DMO12_RS11590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DMO12_RS11605	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DMO12_RS11610	COG2030	dehydratase
DMO12_RS11620	COG0183	Belongs to the thiolase family
DMO12_RS11630	COG0583	DNA-binding transcription factor activity
DMO12_RS11635	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DMO12_RS11645	COG1522	sequence-specific DNA binding
DMO12_RS11650	COG3135	benzoate transporter
DMO12_RS11660	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DMO12_RS11675	COG0589	response to stress
DMO12_RS11680	COG0488	(ABC) transporter
DMO12_RS11700	COG4773	Receptor
DMO12_RS11730	COG0668	transmembrane transport
DMO12_RS11740	COG1309	transcriptional regulator
DMO12_RS11760	COG1605	Chorismate mutase
DMO12_RS11770	COG4221	oxidoreductase activity
DMO12_RS11780	COG0308	aminopeptidase N
DMO12_RS11800	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DMO12_RS11810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DMO12_RS11815	COG1454	alcohol dehydrogenase
DMO12_RS11835	COG0531	amino acid
DMO12_RS11840	COG4303	Ethanolamine ammonia lyase large subunit
DMO12_RS11845	COG4302	ethanolamine ammonia-lyase activity
DMO12_RS11850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DMO12_RS11850	COG0519	Catalyzes the synthesis of GMP from XMP
DMO12_RS11855	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DMO12_RS11865	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DMO12_RS11880	COG0697	spore germination
DMO12_RS11885	COG1923	regulation of RNA biosynthetic process
DMO12_RS11895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DMO12_RS11900	COG0802	atpase or kinase
DMO12_RS11920	COG1187	pseudouridine synthase activity
DMO12_RS11935	COG0583	DNA-binding transcription factor activity
DMO12_RS11950	COG2814	Major facilitator Superfamily
DMO12_RS11955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DMO12_RS11985	COG0729	surface antigen
DMO12_RS12005	COG0174	glutamine synthetase
DMO12_RS12010	COG0745	RESPONSE REGULATOR receiver
DMO12_RS12015	COG2205	protein histidine kinase activity
DMO12_RS12025	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DMO12_RS12030	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DMO12_RS12055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMO12_RS12060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMO12_RS12065	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS12080	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DMO12_RS12085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DMO12_RS12105	COG0583	DNA-binding transcription factor activity
DMO12_RS12125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DMO12_RS12135	COG3658	cytochrome
DMO12_RS12140	COG1215	transferase activity, transferring glycosyl groups
DMO12_RS12145	COG1649	PFAM Uncharacterised BCR, COG1649
DMO12_RS12145	COG0726	polysaccharide deacetylase
DMO12_RS12170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DMO12_RS12175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DMO12_RS12185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DMO12_RS12210	COG0305	Participates in initiation and elongation during chromosome replication
DMO12_RS12215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DMO12_RS12225	COG1305	Transglutaminase-like
DMO12_RS12235	COG2308	Evidence 4 Homologs of previously reported genes of
DMO12_RS12265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DMO12_RS12270	COG0138	bifunctional purine biosynthesis protein purh
DMO12_RS12275	COG0151	Belongs to the GarS family
DMO12_RS12280	COG1464	Belongs to the NlpA lipoprotein family
DMO12_RS12285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DMO12_RS12290	COG2011	ABC-type metal ion transport system permease component
DMO12_RS12295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMO12_RS12305	COG1301	dicarboxylic acid transport
DMO12_RS12335	COG1794	racemase activity, acting on amino acids and derivatives
DMO12_RS12345	COG3008	intermembrane lipid transfer
DMO12_RS12345	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DMO12_RS12350	COG2995	paraquat-inducible protein a
DMO12_RS12360	COG2985	domain, Protein
DMO12_RS12425	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS12445	COG2186	Transcriptional regulator
DMO12_RS12455	COG0786	glutamate:sodium symporter activity
DMO12_RS12460	COG3243	poly(R)-hydroxyalkanoic acid synthase
DMO12_RS12485	COG3111	PFAM Bacterial OB fold (BOF) protein
DMO12_RS12585	COG1610	YqeY-like protein
DMO12_RS12590	COG4783	chaperone-mediated protein folding
DMO12_RS12615	COG1286	toxin biosynthetic process
DMO12_RS12645	COG0778	Nitroreductase
DMO12_RS12655	COG0513	Belongs to the DEAD box helicase family
DMO12_RS12675	COG2363	Small membrane protein
DMO12_RS12705	COG1234	tRNA 3'-trailer cleavage
DMO12_RS12710	COG2195	Cleaves the N-terminal amino acid of tripeptides
DMO12_RS12720	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DMO12_RS12730	COG2819	hydrolase of the alpha beta superfamily
DMO12_RS12735	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS12740	COG1301	dicarboxylic acid transport
DMO12_RS12750	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DMO12_RS12755	COG3139	Protein of unknown function (DUF1315)
DMO12_RS12760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DMO12_RS12765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DMO12_RS12775	COG0494	nUDIX hydrolase
DMO12_RS12785	COG0642	Histidine kinase
DMO12_RS12800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DMO12_RS12810	COG1720	tRNA m6t6A37 methyltransferase activity
DMO12_RS12825	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMO12_RS12830	COG0826	peptidase U32
DMO12_RS12835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DMO12_RS12845	COG4598	ABC transporter
DMO12_RS12850	COG4160	amino acid transport
DMO12_RS12855	COG4215	(ABC) transporter
DMO12_RS12870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS12915	COG1131	(ABC) transporter
DMO12_RS12920	COG0842	Transport permease protein
DMO12_RS12935	COG0772	Belongs to the SEDS family
DMO12_RS12940	COG2951	lytic endotransglycosylase activity
DMO12_RS12965	COG2207	Transcriptional regulator
DMO12_RS12980	COG0052	Belongs to the universal ribosomal protein uS2 family
DMO12_RS12985	COG0024	Methionine aminopeptidase
DMO12_RS12995	COG2223	nitrite transmembrane transporter activity
DMO12_RS13005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMO12_RS13010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DMO12_RS13015	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS13030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DMO12_RS13035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DMO12_RS13040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMO12_RS13060	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMO12_RS13065	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DMO12_RS13070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DMO12_RS13105	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DMO12_RS13115	COG0174	glutamine synthetase
DMO12_RS13130	COG0512	Glutamine amidotransferase of anthranilate synthase
DMO12_RS13135	COG0308	aminopeptidase N
DMO12_RS13165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DMO12_RS13175	COG0302	gtp cyclohydrolase
DMO12_RS13180	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS13200	COG3739	integral membrane protein
DMO12_RS13215	COG1169	isochorismate synthase
DMO12_RS13225	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DMO12_RS13230	COG1132	(ABC) transporter
DMO12_RS13235	COG1132	(ABC) transporter
DMO12_RS13250	COG3433	isochorismatase activity
DMO12_RS13250	COG1535	isochorismatase
DMO12_RS13255	COG1021	2,3-dihydroxybenzoate-AMP ligase
DMO12_RS13260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMO12_RS13270	COG4774	siderophore transport
DMO12_RS13275	COG4607	ABC-type enterochelin transport system periplasmic component
DMO12_RS13280	COG4604	ABC transporter, ATP-binding protein
DMO12_RS13285	COG4605	iron ion homeostasis
DMO12_RS13290	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DMO12_RS13295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMO12_RS13310	COG2964	Protein conserved in bacteria
DMO12_RS13320	COG1741	Belongs to the pirin family
DMO12_RS13340	COG1309	transcriptional regulator
DMO12_RS13350	COG4948	Mandelate Racemase Muconate Lactonizing
DMO12_RS13355	COG2814	Major facilitator Superfamily
DMO12_RS13390	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DMO12_RS13390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DMO12_RS13395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMO12_RS13400	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS13410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMO12_RS13415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMO12_RS13420	COG0583	DNA-binding transcription factor activity
DMO12_RS13425	COG1113	amino acid transport
DMO12_RS13445	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DMO12_RS13445	COG2508	Transcriptional regulator
DMO12_RS13480	COG2879	small protein
DMO12_RS13485	COG1966	Carbon starvation protein
DMO12_RS13530	COG1067	ATP-dependent peptidase activity
DMO12_RS13535	COG0583	DNA-binding transcription factor activity
DMO12_RS13560	COG1686	Belongs to the peptidase S11 family
DMO12_RS13565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DMO12_RS13600	COG0616	signal peptide processing
DMO12_RS13605	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DMO12_RS13615	COG0573	inorganic phosphate transmembrane transporter activity
DMO12_RS13620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DMO12_RS13625	COG1113	amino acid transport
DMO12_RS13630	COG3961	Belongs to the TPP enzyme family
DMO12_RS13635	COG1522	sequence-specific DNA binding
DMO12_RS13645	COG0076	glutamate decarboxylase activity
DMO12_RS13650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMO12_RS13660	COG1309	transcriptional regulator
DMO12_RS13675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMO12_RS13710	COG0352	thiamine-phosphate diphosphorylase activity
DMO12_RS13735	COG0612	Peptidase, M16
DMO12_RS13745	COG1823	symporter activity
DMO12_RS13750	COG0583	DNA-binding transcription factor activity
DMO12_RS13755	COG0477	Major facilitator Superfamily
DMO12_RS13780	COG1187	pseudouridine synthase activity
DMO12_RS13795	COG1686	Belongs to the peptidase S11 family
DMO12_RS13800	COG1252	NADH dehydrogenase
DMO12_RS13810	COG0415	Belongs to the DNA photolyase family
DMO12_RS13825	COG1215	transferase activity, transferring glycosyl groups
DMO12_RS13855	COG2070	2-Nitropropane dioxygenase
DMO12_RS14045	COG5410	chromosome segregation
DMO12_RS14240	COG0556	nucleotide-excision repair
DMO12_RS14260	COG0436	Aminotransferase
DMO12_RS14290	COG4221	oxidoreductase activity
DMO12_RS14300	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DMO12_RS14305	COG1381	Involved in DNA repair and RecF pathway recombination
DMO12_RS14315	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DMO12_RS14330	COG0681	Belongs to the peptidase S26 family
DMO12_RS14345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DMO12_RS14365	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DMO12_RS14370	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DMO12_RS14375	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DMO12_RS14385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DMO12_RS14390	COG4208	sulfate ABC transporter
DMO12_RS14395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DMO12_RS14400	COG0583	DNA-binding transcription factor activity
DMO12_RS14405	COG4625	pathogenesis
DMO12_RS14420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DMO12_RS14435	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DMO12_RS14445	COG1051	belongs to the nudix hydrolase family
DMO12_RS14445	COG1056	cytidyltransferase-related domain
DMO12_RS14450	COG1024	Enoyl-CoA hydratase
DMO12_RS14460	COG2814	Major facilitator Superfamily
DMO12_RS14465	COG0047	phosphoribosylformylglycinamidine synthase activity
DMO12_RS14465	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DMO12_RS14485	COG1473	amidohydrolase
DMO12_RS14490	COG0824	Thioesterase
DMO12_RS14510	COG0823	Involved in the tonB-independent uptake of proteins
DMO12_RS14530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DMO12_RS14565	COG0628	permease
DMO12_RS14575	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DMO12_RS14580	COG0596	Alpha beta hydrolase
DMO12_RS14585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DMO12_RS14585	COG0616	signal peptide processing
DMO12_RS14595	COG0658	competence protein
DMO12_RS14595	COG2333	competence protein COMEC
DMO12_RS14600	COG1136	(ABC) transporter
DMO12_RS14605	COG4591	ABC-type transport system involved in lipoprotein release permease component
DMO12_RS14635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS14655	COG0463	Glycosyl transferase, family 2
DMO12_RS14685	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DMO12_RS14690	COG1280	lysine exporter protein (LysE YggA)
DMO12_RS14700	COG0019	diaminopimelate decarboxylase activity
DMO12_RS14710	COG1113	amino acid transport
DMO12_RS14725	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DMO12_RS14735	COG3339	Conserved Protein
DMO12_RS14740	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DMO12_RS14745	COG0243	molybdopterin cofactor binding
DMO12_RS14750	COG1929	Belongs to the glycerate kinase type-1 family
DMO12_RS14765	COG0778	Nitroreductase
DMO12_RS14790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMO12_RS14805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DMO12_RS14830	COG0741	lytic transglycosylase activity
DMO12_RS14850	COG0584	glycerophosphoryl diester phosphodiesterase
DMO12_RS14855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DMO12_RS14880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DMO12_RS14885	COG1597	lipid kinase activity
DMO12_RS14900	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DMO12_RS14905	COG0477	Major facilitator Superfamily
DMO12_RS14955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DMO12_RS14960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DMO12_RS14985	COG0505	Belongs to the CarA family
DMO12_RS15005	COG0589	response to stress
DMO12_RS15020	COG2843	Capsule synthesis protein
DMO12_RS15040	COG2321	neutral zinc metallopeptidase
DMO12_RS15045	COG2354	Protein conserved in bacteria
DMO12_RS15065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DMO12_RS15090	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DMO12_RS15095	COG1053	succinate dehydrogenase
DMO12_RS15100	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DMO12_RS15105	COG2009	succinate dehydrogenase
DMO12_RS15130	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS15155	COG2921	Belongs to the UPF0250 family
DMO12_RS15160	COG0321	lipoyl(octanoyl) transferase activity
DMO12_RS15175	COG0531	amino acid
DMO12_RS15185	COG1733	regulation of RNA biosynthetic process
DMO12_RS15190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DMO12_RS15195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DMO12_RS15195	COG1648	precorrin-2 dehydrogenase activity
DMO12_RS15210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DMO12_RS15240	COG0671	phosphoesterase, PA-phosphatase related
DMO12_RS15245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS15255	COG1538	Outer membrane efflux protein
DMO12_RS15260	COG0393	Putative heavy-metal-binding
DMO12_RS15265	COG0393	Putative heavy-metal-binding
DMO12_RS15275	COG1028	Short-chain dehydrogenase reductase Sdr
DMO12_RS15285	COG0525	valine-tRNA ligase activity
DMO12_RS15305	COG0583	DNA-binding transcription factor activity
DMO12_RS15315	COG0004	ammonium transporteR
DMO12_RS15325	COG0642	Histidine kinase
DMO12_RS15330	COG0745	RESPONSE REGULATOR receiver
DMO12_RS15335	COG2194	sulfuric ester hydrolase activity
DMO12_RS15355	COG1752	Esterase of the alpha-beta hydrolase superfamily
DMO12_RS15370	COG2315	Protein conserved in bacteria
DMO12_RS15375	COG0142	geranyltranstransferase activity
DMO12_RS15380	COG2828	Protein conserved in bacteria
DMO12_RS15385	COG1113	amino acid transport
DMO12_RS15405	COG2207	Transcriptional regulator
DMO12_RS15430	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMO12_RS15440	COG0560	Phosphoserine phosphatase
DMO12_RS15450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DMO12_RS15460	COG1530	ribonuclease E activity
DMO12_RS15465	COG0424	maF-like protein
DMO12_RS15470	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DMO12_RS15475	COG1792	Involved in formation and maintenance of cell shape
DMO12_RS15480	COG1077	Cell shape determining protein MreB Mrl
DMO12_RS15485	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMO12_RS15495	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DMO12_RS15525	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DMO12_RS15530	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DMO12_RS15535	COG1752	Esterase of the alpha-beta hydrolase superfamily
DMO12_RS15540	COG1115	amino acid carrier protein
DMO12_RS15560	COG2814	Major facilitator Superfamily
DMO12_RS15565	COG1289	transmembrane transporter activity
DMO12_RS15575	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DMO12_RS15615	COG1376	ErfK ybiS ycfS ynhG family protein
DMO12_RS15620	COG2832	Protein of unknown function (DUF454)
DMO12_RS15630	COG5510	response to toxic substance
DMO12_RS15650	COG0840	transmembrane signaling receptor activity
DMO12_RS15690	COG3422	double-strand break repair
DMO12_RS15695	COG2824	Alkylphosphonate utilization operon protein PhnA
DMO12_RS15700	COG3189	MarR family transcriptional regulator
DMO12_RS15710	COG0354	folic acid binding
DMO12_RS15715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMO12_RS15730	COG1902	pentaerythritol trinitrate reductase activity
DMO12_RS15735	COG4772	TonB-dependent receptor
DMO12_RS15740	COG2094	Belongs to the DNA glycosylase MPG family
DMO12_RS15765	COG1217	gtp-binding protein TYPA
DMO12_RS15770	COG2233	PERMEase
DMO12_RS15780	COG0833	amino acid
DMO12_RS15785	COG1690	Belongs to the RtcB family
DMO12_RS15790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DMO12_RS15790	COG2885	chlorophyll binding
DMO12_RS15800	COG0183	Belongs to the thiolase family
DMO12_RS15820	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DMO12_RS15840	COG2207	Transcriptional regulator
DMO12_RS15845	COG0183	Belongs to the thiolase family
DMO12_RS15875	COG1272	protein, Hemolysin III
DMO12_RS15880	COG0477	Major facilitator Superfamily
DMO12_RS15895	COG0450	alkyl hydroperoxide reductase
DMO12_RS15915	COG0285	dihydrofolate synthase activity
DMO12_RS15965	COG2096	Adenosyltransferase
DMO12_RS15985	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DMO12_RS15990	COG0745	RESPONSE REGULATOR receiver
DMO12_RS15995	COG2205	protein histidine kinase activity
DMO12_RS16005	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16010	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16015	COG0583	DNA-binding transcription factor activity
DMO12_RS16020	COG0625	glutathione transferase activity
DMO12_RS16085	COG0438	transferase activity, transferring glycosyl groups
DMO12_RS16090	COG0463	Glycosyl transferase, family 2
DMO12_RS16095	COG0726	polysaccharide deacetylase
DMO12_RS16115	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DMO12_RS16120	COG2205	protein histidine kinase activity
DMO12_RS16170	COG1862	Preprotein translocase
DMO12_RS16180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DMO12_RS16185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DMO12_RS16195	COG3781	membrane
DMO12_RS16200	COG0613	PHP domain protein
DMO12_RS16210	COG2350	Protein conserved in bacteria
DMO12_RS16240	COG1607	acyl-coa hydrolase
DMO12_RS16300	COG2199	diguanylate cyclase activity
DMO12_RS16310	COG1408	metallophosphoesterase
DMO12_RS16315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DMO12_RS16325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DMO12_RS16345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DMO12_RS16350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DMO12_RS16365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DMO12_RS16375	COG2969	positive regulation of protein catabolic process
DMO12_RS16395	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS16400	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DMO12_RS16420	COG1309	transcriptional regulator
DMO12_RS16425	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16470	COG1183	phosphatidylcholine synthase activity
DMO12_RS16475	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DMO12_RS16505	COG0741	lytic transglycosylase activity
DMO12_RS16505	COG0739	heme binding
DMO12_RS16505	COG1196	nuclear chromosome segregation
DMO12_RS16515	COG1702	phosphate starvation-inducible protein PhoH
DMO12_RS16550	COG1295	ribonuclease BN
DMO12_RS16555	COG0697	spore germination
DMO12_RS16560	COG2169	Transcriptional regulator
DMO12_RS16565	COG0179	Fumarylacetoacetate (FAA) hydrolase
DMO12_RS16610	COG0557	exoribonuclease II activity
DMO12_RS16615	COG0339	signal peptide processing
DMO12_RS16620	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DMO12_RS16650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DMO12_RS16655	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16810	COG0626	cystathionine gamma-synthase activity
DMO12_RS16815	COG0433	COG0433 Predicted ATPase
DMO12_RS16820	COG1017	nitric oxide dioxygenase activity
DMO12_RS16820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DMO12_RS16825	COG1959	2 iron, 2 sulfur cluster binding
DMO12_RS16840	COG1301	dicarboxylic acid transport
DMO12_RS16845	COG1946	Acyl-CoA thioesterase
DMO12_RS16865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DMO12_RS16870	COG1040	competence protein
DMO12_RS16875	COG0494	nUDIX hydrolase
DMO12_RS16885	COG0598	Magnesium transport protein CorA
DMO12_RS16895	COG2854	intermembrane phospholipid transfer
DMO12_RS16905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DMO12_RS16910	COG1127	ABC transporter
DMO12_RS16920	COG0513	Belongs to the DEAD box helicase family
DMO12_RS16940	COG0408	coproporphyrinogen oxidase activity
DMO12_RS16955	COG1960	acyl-CoA dehydrogenase activity
DMO12_RS16965	COG1983	PspC domain protein
DMO12_RS16970	COG0517	IMP dehydrogenase activity
DMO12_RS17015	COG0583	DNA-binding transcription factor activity
DMO12_RS17055	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS17065	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DMO12_RS17070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DMO12_RS17075	COG0833	amino acid
DMO12_RS17105	COG1192	Involved in chromosome partitioning
DMO12_RS17110	COG0628	permease
DMO12_RS17120	COG1289	transmembrane transporter activity
DMO12_RS17135	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMO12_RS17140	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DMO12_RS17150	COG0277	FAD linked oxidase domain protein
DMO12_RS17155	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DMO12_RS17180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DMO12_RS17185	COG5380	lipid catabolic process
DMO12_RS17205	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DMO12_RS17255	COG0194	GDP metabolic process
DMO12_RS17270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DMO12_RS17290	COG3307	-O-antigen
DMO12_RS17310	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DMO12_RS17315	COG1704	LemA family
DMO12_RS17325	COG0493	'glutamate synthase
DMO12_RS17330	COG0067	glutamate synthase
DMO12_RS17330	COG0070	glutamate synthase
DMO12_RS17330	COG0069	glutamate synthase activity
DMO12_RS17380	COG2226	methyltransferase
DMO12_RS17395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DMO12_RS17400	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DMO12_RS17445	COG0833	amino acid
DMO12_RS17510	COG0488	(ABC) transporter
DMO12_RS17515	COG2873	o-acetylhomoserine
DMO12_RS17520	COG4221	oxidoreductase activity
DMO12_RS17525	COG0659	secondary active sulfate transmembrane transporter activity
DMO12_RS17550	COG0427	acetyl-CoA hydrolase
DMO12_RS17580	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DMO12_RS17620	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DMO12_RS17675	COG2207	Transcriptional regulator
DMO12_RS17680	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DMO12_RS17695	COG2249	NAD(P)H dehydrogenase (quinone) activity
DMO12_RS17705	COG1733	regulation of RNA biosynthetic process
DMO12_RS17720	COG1733	regulation of RNA biosynthetic process
DMO12_RS17745	COG0667	Aldo Keto reductase
DMO12_RS17770	COG0583	DNA-binding transcription factor activity
DMO12_RS17775	COG2814	Major facilitator Superfamily
DMO12_RS17805	COG1335	isochorismatase
DMO12_RS17815	COG1012	belongs to the aldehyde dehydrogenase family
DMO12_RS17820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DMO12_RS17830	COG1113	amino acid transport
DMO12_RS17840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DMO12_RS17855	COG2814	Major facilitator Superfamily
DMO12_RS17865	COG0351	phosphomethylpyrimidine kinase
DMO12_RS17865	COG0352	thiamine-phosphate diphosphorylase activity
DMO12_RS17865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DMO12_RS17885	COG1309	transcriptional regulator
DMO12_RS17890	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DMO12_RS17905	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DMO12_RS17915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DMO12_RS17920	COG3162	membrane
DMO12_RS17925	COG2198	Histidine kinase
DMO12_RS17925	COG2205	protein histidine kinase activity
DMO12_RS17925	COG0784	Response regulator, receiver
DMO12_RS17950	COG1522	sequence-specific DNA binding
DMO12_RS17955	COG1335	isochorismatase
DMO12_RS17960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DMO12_RS17970	COG0668	transmembrane transport
DMO12_RS17975	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DMO12_RS17980	COG1519	Transferase
DMO12_RS17985	COG1902	pentaerythritol trinitrate reductase activity
DMO12_RS18005	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DMO12_RS18030	COG0426	domain, Protein
DMO12_RS18030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DMO12_RS18035	COG4774	siderophore transport
DMO12_RS18040	COG2119	membrane
DMO12_RS18050	COG0508	dehydrogenase complex catalyzes the overall conversion of
DMO12_RS18060	COG4942	peptidase
DMO12_RS18075	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DMO12_RS18085	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DMO12_RS18105	COG0189	ligase activity
DMO12_RS18125	COG0708	Exodeoxyribonuclease III
DMO12_RS18130	COG1393	Belongs to the ArsC family
DMO12_RS18185	COG2233	PERMEase
DMO12_RS18195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DMO12_RS18205	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DMO12_RS18215	COG3150	esterase
DMO12_RS18240	COG3179	chitinase
DMO12_RS18255	COG2918	glutathione biosynthetic process
DMO12_RS18270	COG2733	membrane
DMO12_RS18275	COG0436	Aminotransferase
DMO12_RS18280	COG0534	Mate efflux family protein
DMO12_RS18340	COG0753	catalase activity
DMO12_RS18390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DMO12_RS18395	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DMO12_RS18405	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DMO12_RS18410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DMO12_RS18415	COG0546	phosphoglycolate phosphatase activity
DMO12_RS18425	COG0010	Belongs to the arginase family
DMO12_RS18455	COG2188	Transcriptional regulator
DMO12_RS18465	COG0523	cobalamin synthesis protein
DMO12_RS18475	COG1113	amino acid transport
DMO12_RS18485	COG0625	glutathione transferase activity
DMO12_RS18505	COG1683	Conserved Protein
DMO12_RS18510	COG0534	Mate efflux family protein
DMO12_RS18515	COG0385	Bile acid
DMO12_RS18520	COG1335	isochorismatase
DMO12_RS18525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DMO12_RS18545	COG2116	formate transmembrane transporter activity
DMO12_RS18550	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DMO12_RS18555	COG2133	pyrroloquinoline quinone binding
DMO12_RS18560	COG2983	Belongs to the UPF0260 family
DMO12_RS18580	COG1194	a g-specific adenine glycosylase
DMO12_RS18595	COG2818	Glycosylase
DMO12_RS18600	COG1064	alcohol dehydrogenase
DMO12_RS18605	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DMO12_RS18620	COG0583	DNA-binding transcription factor activity
DMO12_RS18625	COG0656	L-ascorbic acid biosynthetic process
DMO12_RS18630	COG2814	Major facilitator Superfamily
DMO12_RS18665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DMO12_RS18680	COG2233	PERMEase
DMO12_RS18720	COG0733	neurotransmitter:sodium symporter activity
DMO12_RS18800	COG1192	Involved in chromosome partitioning
DMO12_RS18825	COG2026	Addiction module toxin, RelE StbE family
DMO12_RS18835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DMO12_RS18980	COG1525	nuclease
DMO12_RS19045	COG1475	DNA binding
DMO12_RS19065	COG3853	Toxic anion resistance protein (TelA)
DMO12_RS19160	COG0484	heat shock protein binding
DMO12_RS19230	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS19240	COG2826	transposase and inactivated derivatives, IS30 family
DMO12_RS19270	COG0741	lytic transglycosylase activity
DMO12_RS19305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DMO12_RS19385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII