locus-tag	class	description
AM435_RS00025	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AM435_RS00070	COG0419	ATPase involved in DNA repair
AM435_RS00115	COG3173	Aminoglycoside phosphotransferase
AM435_RS00120	COG0488	(ABC) transporter
AM435_RS00150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM435_RS00175	COG0756	dUTP diphosphatase activity
AM435_RS00420	COG1475	DNA binding
AM435_RS00425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM435_RS00535	COG0791	NLP P60 protein
AM435_RS00585	COG0358	DNA primase activity
AM435_RS00625	COG0194	GDP metabolic process
AM435_RS00650	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM435_RS00730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM435_RS00765	COG0741	lytic transglycosylase activity
AM435_RS00795	COG2826	transposase and inactivated derivatives, IS30 family
AM435_RS00865	COG0484	heat shock protein binding
AM435_RS00970	COG3853	Toxic anion resistance protein (TelA)
AM435_RS00990	COG1475	DNA binding
AM435_RS01070	COG1525	nuclease
AM435_RS01140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM435_RS01205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM435_RS01210	COG2814	Major facilitator Superfamily
AM435_RS01225	COG0583	DNA-binding transcription factor activity
AM435_RS01240	COG1187	pseudouridine synthase activity
AM435_RS01260	COG0802	atpase or kinase
AM435_RS01265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM435_RS01275	COG1923	regulation of RNA biosynthetic process
AM435_RS01280	COG0697	spore germination
AM435_RS01295	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM435_RS01305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM435_RS01310	COG0519	Catalyzes the synthesis of GMP from XMP
AM435_RS01310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM435_RS01315	COG4302	ethanolamine ammonia-lyase activity
AM435_RS01320	COG4303	Ethanolamine ammonia lyase large subunit
AM435_RS01325	COG0531	amino acid
AM435_RS01345	COG1454	alcohol dehydrogenase
AM435_RS01350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM435_RS01360	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AM435_RS01380	COG0308	aminopeptidase N
AM435_RS01390	COG4221	oxidoreductase activity
AM435_RS01400	COG1605	Chorismate mutase
AM435_RS01420	COG1309	transcriptional regulator
AM435_RS01430	COG0668	transmembrane transport
AM435_RS01455	COG0488	(ABC) transporter
AM435_RS01460	COG0589	response to stress
AM435_RS01475	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM435_RS01485	COG3135	benzoate transporter
AM435_RS01490	COG1522	sequence-specific DNA binding
AM435_RS01500	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM435_RS01505	COG0583	DNA-binding transcription factor activity
AM435_RS01515	COG0183	Belongs to the thiolase family
AM435_RS01525	COG2030	dehydratase
AM435_RS01530	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM435_RS01545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM435_RS01555	COG0824	Thioesterase
AM435_RS01560	COG1454	alcohol dehydrogenase
AM435_RS01570	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM435_RS01590	COG0069	glutamate synthase activity
AM435_RS01895	COG2026	Addiction module toxin, RelE StbE family
AM435_RS01935	COG0592	DNA-directed DNA polymerase activity
AM435_RS02010	COG2814	Major facilitator Superfamily
AM435_RS02025	COG0511	ligase activity, forming carbon-carbon bonds
AM435_RS02045	COG1116	anion transmembrane transporter activity
AM435_RS02045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM435_RS02050	COG0745	RESPONSE REGULATOR receiver
AM435_RS02060	COG2146	nitrite reductase [NAD(P)H] activity
AM435_RS02060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM435_RS02065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM435_RS02070	COG0243	molybdopterin cofactor binding
AM435_RS02080	COG0243	molybdopterin cofactor binding
AM435_RS02085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM435_RS02100	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM435_RS02100	COG0315	cyclic pyranopterin monophosphate synthase activity
AM435_RS02105	COG0303	'Molybdopterin
AM435_RS02115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM435_RS02120	COG0697	spore germination
AM435_RS02140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM435_RS02145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM435_RS02205	COG2204	response regulator
AM435_RS02210	COG3852	Histidine kinase
AM435_RS02230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM435_RS02235	COG0575	Belongs to the CDS family
AM435_RS02270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM435_RS02285	COG2137	regulation of response to DNA damage stimulus
AM435_RS02295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM435_RS02300	COG1011	Hydrolase
AM435_RS02325	COG1522	sequence-specific DNA binding
AM435_RS02335	COG1113	amino acid transport
AM435_RS02350	COG0659	secondary active sulfate transmembrane transporter activity
AM435_RS02355	COG2135	peptidase activity
AM435_RS02370	COG5001	Diguanylate cyclase
AM435_RS02370	COG3300	MHYT domain
AM435_RS02390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM435_RS02390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM435_RS02390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM435_RS02395	COG1105	Belongs to the carbohydrate kinase PfkB family
AM435_RS02400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM435_RS02400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM435_RS02430	COG0024	Methionine aminopeptidase
AM435_RS02435	COG0583	DNA-binding transcription factor activity
AM435_RS02445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM435_RS02450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM435_RS02455	COG0516	GMP reductase activity
AM435_RS02455	COG0517	IMP dehydrogenase activity
AM435_RS02480	COG0552	protein localization to endoplasmic reticulum
AM435_RS02490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AM435_RS02505	COG4890	Cyd operon protein YbgT
AM435_RS02510	COG1294	oxidase, subunit
AM435_RS02530	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM435_RS02540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM435_RS02545	COG4774	siderophore transport
AM435_RS02560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM435_RS02565	COG0569	domain protein
AM435_RS02570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM435_RS02600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM435_RS02605	COG0542	response to heat
AM435_RS02630	COG1902	pentaerythritol trinitrate reductase activity
AM435_RS02630	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM435_RS02675	COG2323	membrane
AM435_RS02680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM435_RS02690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM435_RS02695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM435_RS02700	COG0183	Belongs to the thiolase family
AM435_RS02705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM435_RS02710	COG0596	Alpha beta hydrolase
AM435_RS02715	COG2271	Major facilitator Superfamily
AM435_RS02720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM435_RS02725	COG3485	protocatechuate 3,4-dioxygenase
AM435_RS02730	COG3485	protocatechuate 3,4-dioxygenase
AM435_RS02735	COG0710	3-dehydroquinate dehydratase activity
AM435_RS02740	COG3420	alginic acid biosynthetic process
AM435_RS02745	COG3659	wide pore channel activity
AM435_RS02750	COG4993	Dehydrogenase
AM435_RS02760	COG2391	methyltransferase activity
AM435_RS02775	COG1414	Transcriptional regulator
AM435_RS02780	COG0583	DNA-binding transcription factor activity
AM435_RS02785	COG1960	acyl-CoA dehydrogenase activity
AM435_RS02810	COG2814	Major facilitator Superfamily
AM435_RS02820	COG0154	amidase activity
AM435_RS02840	COG4638	Rieske (2fe-2S)
AM435_RS02850	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS02860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM435_RS02870	COG3733	amine oxidase
AM435_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS02890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM435_RS02895	COG0183	Belongs to the thiolase family
AM435_RS02900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM435_RS02905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM435_RS02915	COG4829	muconolactone delta-isomerase
AM435_RS02920	COG4948	Mandelate Racemase Muconate Lactonizing
AM435_RS02925	COG0583	DNA-binding transcription factor activity
AM435_RS02955	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS02960	COG0129	dihydroxy-acid dehydratase activity
AM435_RS02970	COG0583	DNA-binding transcription factor activity
AM435_RS02975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM435_RS02985	COG2084	Dehydrogenase
AM435_RS02990	COG2207	Transcriptional regulator
AM435_RS03005	COG1064	alcohol dehydrogenase
AM435_RS03015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM435_RS03020	COG1120	ATPase activity
AM435_RS03040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM435_RS03160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM435_RS03215	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS03230	COG2207	Transcriptional regulator
AM435_RS03240	COG2205	protein histidine kinase activity
AM435_RS03245	COG0745	RESPONSE REGULATOR receiver
AM435_RS03250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM435_RS03255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM435_RS03260	COG1538	Outer membrane efflux protein
AM435_RS03270	COG2072	flavoprotein involved in K transport
AM435_RS03290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM435_RS03310	COG3539	Fimbrial protein
AM435_RS03335	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM435_RS03345	COG0753	catalase activity
AM435_RS03360	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM435_RS03425	COG1535	isochorismatase
AM435_RS03425	COG3433	isochorismatase activity
AM435_RS03430	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS03435	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM435_RS03440	COG4149	molybdate abc transporter
AM435_RS03445	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM435_RS03455	COG4638	Rieske (2fe-2S)
AM435_RS03460	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM435_RS03465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM435_RS03465	COG0543	2 iron, 2 sulfur cluster binding
AM435_RS03490	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS03505	COG2207	Transcriptional regulator
AM435_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS03515	COG2610	gluconate transmembrane transporter activity
AM435_RS03525	COG0583	DNA-binding transcription factor activity
AM435_RS03535	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM435_RS03540	COG2031	fatty acid transporter
AM435_RS03545	COG0183	Belongs to the thiolase family
AM435_RS03550	COG0583	DNA-binding transcription factor activity
AM435_RS03555	COG0583	DNA-binding transcription factor activity
AM435_RS03570	COG1027	Aspartate ammonia-lyase
AM435_RS03580	COG0477	Major facilitator Superfamily
AM435_RS03600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM435_RS03605	COG4521	taurine ABC transporter
AM435_RS03620	COG2188	Transcriptional regulator
AM435_RS03630	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM435_RS03635	COG1733	regulation of RNA biosynthetic process
AM435_RS03640	COG3708	Transcriptional regulator
AM435_RS03640	COG2207	Transcriptional regulator
AM435_RS03655	COG0730	response to heat
AM435_RS03665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM435_RS03665	COG3453	Protein conserved in bacteria
AM435_RS03675	COG3781	membrane
AM435_RS03680	COG1063	alcohol dehydrogenase
AM435_RS03705	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM435_RS03710	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM435_RS03715	COG0022	dehydrogenase e1 component
AM435_RS03720	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM435_RS03725	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM435_RS03745	COG3706	GGDEF domain
AM435_RS03760	COG0133	tryptophan synthase activity
AM435_RS03770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM435_RS03805	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM435_RS03830	COG2226	methyltransferase
AM435_RS03885	COG0842	Transport permease protein
AM435_RS03890	COG0842	Transport permease protein
AM435_RS03895	COG1131	(ABC) transporter
AM435_RS03910	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM435_RS03935	COG0730	response to heat
AM435_RS03940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM435_RS03960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM435_RS04020	COG4264	IucA IucC family
AM435_RS04025	COG4264	IucA IucC family
AM435_RS04045	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM435_RS04060	COG1960	acyl-CoA dehydrogenase activity
AM435_RS04065	COG1960	acyl-CoA dehydrogenase activity
AM435_RS04070	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM435_RS04075	COG2207	Transcriptional regulator
AM435_RS04080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM435_RS04085	COG0776	regulation of translation
AM435_RS04110	COG0822	iron-sulfur transferase activity
AM435_RS04115	COG0316	Belongs to the HesB IscA family
AM435_RS04145	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM435_RS04165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM435_RS04170	COG0702	epimerase
AM435_RS04215	COG0339	signal peptide processing
AM435_RS04275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM435_RS04280	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM435_RS04310	COG0776	regulation of translation
AM435_RS04375	COG0084	hydrolase, TatD family'
AM435_RS04395	COG1663	tetraacyldisaccharide 4'-kinase activity
AM435_RS04400	COG1132	(ABC) transporter
AM435_RS04410	COG0811	peptide transport
AM435_RS04415	COG1475	DNA binding
AM435_RS04420	COG1192	Involved in chromosome partitioning
AM435_RS04430	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM435_RS04445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM435_RS04450	COG0191	fructose-bisphosphate aldolase activity
AM435_RS04470	COG0424	maF-like protein
AM435_RS04475	COG2850	peptidyl-arginine hydroxylation
AM435_RS04485	COG0640	Transcriptional regulator
AM435_RS04495	COG3619	membrane
AM435_RS04500	COG3122	Protein conserved in bacteria
AM435_RS04505	COG1132	(ABC) transporter
AM435_RS04530	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM435_RS04535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM435_RS04545	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM435_RS04545	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM435_RS04545	COG0506	proline dehydrogenase activity
AM435_RS04550	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM435_RS04565	COG3698	Phosphodiester glycosidase
AM435_RS04575	COG2353	YceI-like domain
AM435_RS04585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM435_RS04630	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM435_RS04630	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM435_RS04655	COG3539	Fimbrial protein
AM435_RS04660	COG3121	Chaperone
AM435_RS04700	COG0697	spore germination
AM435_RS04710	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM435_RS04720	COG0583	DNA-binding transcription factor activity
AM435_RS04745	COG1309	transcriptional regulator
AM435_RS04760	COG1522	sequence-specific DNA binding
AM435_RS04770	COG1126	abc transporter atp-binding protein
AM435_RS04775	COG0765	amino acid transport
AM435_RS04780	COG0765	amino acid transport
AM435_RS04810	COG1464	Belongs to the NlpA lipoprotein family
AM435_RS04820	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM435_RS04825	COG2011	ABC-type metal ion transport system permease component
AM435_RS04830	COG0012	GTP binding
AM435_RS04860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM435_RS04900	COG0386	Belongs to the glutathione peroxidase family
AM435_RS04910	COG0436	Aminotransferase
AM435_RS04950	COG3634	alkyl hydroperoxide reductase activity
AM435_RS04965	COG0583	DNA-binding transcription factor activity
AM435_RS04970	COG0798	PFAM Bile acid sodium symporter
AM435_RS04975	COG0640	Transcriptional regulator
AM435_RS04990	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM435_RS05000	COG0583	DNA-binding transcription factor activity
AM435_RS05010	COG1953	Uracil, thiamine, allantoin
AM435_RS05020	COG2175	clavaminate synthase activity
AM435_RS05025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM435_RS05030	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM435_RS05035	COG4521	taurine ABC transporter
AM435_RS05055	COG0477	Major facilitator Superfamily
AM435_RS05080	COG1271	oxidase subunit
AM435_RS05085	COG1294	oxidase, subunit
AM435_RS05095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM435_RS05115	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM435_RS05135	COG3052	prosthetic group binding
AM435_RS05140	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM435_RS05150	COG2814	Major facilitator Superfamily
AM435_RS05170	COG1346	cytolysis
AM435_RS05180	COG0583	DNA-binding transcription factor activity
AM435_RS05185	COG0625	glutathione transferase activity
AM435_RS05190	COG0625	glutathione transferase activity
AM435_RS05195	COG0583	DNA-binding transcription factor activity
AM435_RS05210	COG1045	serine acetyltransferase
AM435_RS05215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM435_RS05220	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM435_RS05230	COG1280	lysine exporter protein (LysE YggA)
AM435_RS05245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM435_RS05250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM435_RS05255	COG1126	abc transporter atp-binding protein
AM435_RS05260	COG0765	amino acid transport
AM435_RS05265	COG0765	amino acid transport
AM435_RS05285	COG0784	Response regulator, receiver
AM435_RS05285	COG2205	protein histidine kinase activity
AM435_RS05305	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM435_RS05325	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS05370	COG0583	DNA-binding transcription factor activity
AM435_RS05390	COG0318	PFAM AMP-dependent synthetase and ligase
AM435_RS05395	COG1309	transcriptional regulator
AM435_RS05400	COG1960	acyl-CoA dehydrogenase activity
AM435_RS05405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM435_RS05410	COG1024	Enoyl-CoA hydratase
AM435_RS05415	COG4770	biotin carboxylase activity
AM435_RS05425	COG0583	DNA-binding transcription factor activity
AM435_RS05440	COG1960	acyl-CoA dehydrogenase activity
AM435_RS05450	COG2814	Major facilitator Superfamily
AM435_RS05460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM435_RS05465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM435_RS05470	COG2814	Major facilitator Superfamily
AM435_RS05475	COG1960	acyl-CoA dehydrogenase activity
AM435_RS05480	COG1024	Enoyl-CoA hydratase
AM435_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS05490	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM435_RS05495	COG0183	Belongs to the thiolase family
AM435_RS05505	COG2814	Major facilitator Superfamily
AM435_RS05515	COG1024	Enoyl-CoA hydratase
AM435_RS05530	COG1960	acyl-CoA dehydrogenase activity
AM435_RS05535	COG2814	Major facilitator Superfamily
AM435_RS05540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM435_RS05545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM435_RS05560	COG3842	ATPase activity
AM435_RS05565	COG1840	ABC-type Fe3 transport system, periplasmic component
AM435_RS05575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM435_RS05580	COG1414	Transcriptional regulator
AM435_RS05590	COG0583	DNA-binding transcription factor activity
AM435_RS05595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM435_RS05600	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS05610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM435_RS05620	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS05625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM435_RS05630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM435_RS05635	COG2267	carboxylic ester hydrolase activity
AM435_RS05655	COG3038	cytochrome b561
AM435_RS05660	COG0753	catalase activity
AM435_RS05700	COG2050	protein possibly involved in aromatic compounds catabolism
AM435_RS05710	COG3327	negative regulation of DNA-templated transcription, initiation
AM435_RS05715	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM435_RS05720	COG0183	Belongs to the thiolase family
AM435_RS05725	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM435_RS05730	COG1024	Enoyl-CoA hydratase
AM435_RS05735	COG1024	Enoyl-CoA hydratase
AM435_RS05740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM435_RS05745	COG2151	metal-sulfur cluster biosynthetic enzyme
AM435_RS05750	COG3396	Phenylacetate-CoA oxygenase
AM435_RS05755	COG3460	Phenylacetate-CoA oxygenase
AM435_RS05760	COG3396	Phenylacetate-CoA oxygenase
AM435_RS05765	COG2030	dehydratase
AM435_RS05765	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS05770	COG1760	l-serine dehydratase
AM435_RS05775	COG0531	amino acid
AM435_RS05780	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS05805	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM435_RS05815	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM435_RS05835	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM435_RS05855	COG0789	Transcriptional regulator
AM435_RS05865	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM435_RS05880	COG2807	transmembrane transport
AM435_RS05885	COG0590	tRNA wobble adenosine to inosine editing
AM435_RS06005	COG1116	anion transmembrane transporter activity
AM435_RS06010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM435_RS06020	COG0864	Transcriptional regulator
AM435_RS06040	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM435_RS06045	COG0439	Biotin carboxylase
AM435_RS06060	COG1063	alcohol dehydrogenase
AM435_RS06070	COG1309	transcriptional regulator
AM435_RS06095	COG0038	chloride channel
AM435_RS06100	COG4770	biotin carboxylase activity
AM435_RS06120	COG1914	H( )-stimulated, divalent metal cation uptake system
AM435_RS06125	COG0583	DNA-binding transcription factor activity
AM435_RS06180	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM435_RS06200	COG2814	Major facilitator Superfamily
AM435_RS06210	COG1560	Kdo2-lipid A biosynthetic process
AM435_RS06220	COG5006	permease, DMT superfamily
AM435_RS06225	COG1522	sequence-specific DNA binding
AM435_RS06240	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM435_RS06250	COG4122	O-methyltransferase activity
AM435_RS06285	COG1137	ATPase activity
AM435_RS06290	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM435_RS06300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM435_RS06305	COG0517	IMP dehydrogenase activity
AM435_RS06305	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AM435_RS06345	COG2814	Major facilitator Superfamily
AM435_RS06395	COG1278	Cold shock
AM435_RS06400	COG1280	lysine exporter protein (LysE YggA)
AM435_RS06435	COG1570	exodeoxyribonuclease VII activity
AM435_RS06490	COG0583	DNA-binding transcription factor activity
AM435_RS06495	COG4638	Rieske (2fe-2S)
AM435_RS06500	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM435_RS06505	COG0543	2 iron, 2 sulfur cluster binding
AM435_RS06505	COG0633	Ferredoxin
AM435_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS06515	COG3135	benzoate transporter
AM435_RS06520	COG2814	Major facilitator Superfamily
AM435_RS06535	COG1643	Atp-dependent helicase
AM435_RS06540	COG0450	alkyl hydroperoxide reductase
AM435_RS06550	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM435_RS06560	COG3634	alkyl hydroperoxide reductase activity
AM435_RS06580	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM435_RS06585	COG0625	glutathione transferase activity
AM435_RS06595	COG2885	chlorophyll binding
AM435_RS06630	COG0542	response to heat
AM435_RS06645	COG1765	OsmC-like protein
AM435_RS06655	COG0667	Aldo Keto reductase
AM435_RS06670	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM435_RS06680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM435_RS06690	COG0527	aspartate kinase activity
AM435_RS06700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM435_RS06710	COG3038	cytochrome b561
AM435_RS06715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM435_RS06720	COG2252	PERMEase
AM435_RS06740	COG1660	Displays ATPase and GTPase activities
AM435_RS06745	COG2746	aminoglycoside 3-N-acetyltransferase activity
AM435_RS06810	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM435_RS06815	COG0583	DNA-binding transcription factor activity
AM435_RS06830	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM435_RS06875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM435_RS06890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM435_RS06905	COG2814	Major facilitator Superfamily
AM435_RS06910	COG1024	Enoyl-CoA hydratase
AM435_RS06915	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS06925	COG1960	acyl-CoA dehydrogenase activity
AM435_RS06950	COG2186	Transcriptional regulator
AM435_RS06955	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS06965	COG4948	Mandelate Racemase Muconate Lactonizing
AM435_RS06970	COG2271	Major facilitator Superfamily
AM435_RS06975	COG2721	sulfolactate sulfo-lyase activity
AM435_RS06980	COG0697	spore germination
AM435_RS06995	COG1113	amino acid transport
AM435_RS07005	COG1113	amino acid transport
AM435_RS07025	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS07045	COG0531	amino acid
AM435_RS07080	COG3209	COG3209 Rhs family protein
AM435_RS07105	COG4269	membrane
AM435_RS07120	COG1902	pentaerythritol trinitrate reductase activity
AM435_RS07120	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM435_RS07130	COG5001	Diguanylate cyclase
AM435_RS07130	COG4251	negative regulation of phosphorylation
AM435_RS07130	COG3706	GGDEF domain
AM435_RS07130	COG2203	Gaf domain
AM435_RS07140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM435_RS07160	COG4172	Belongs to the ABC transporter superfamily
AM435_RS07165	COG4239	(ABC) transporter, permease
AM435_RS07170	COG4174	ABC transporter (Permease)
AM435_RS07180	COG1388	LysM domain
AM435_RS07180	COG1388	LysM domain
AM435_RS07180	COG0741	lytic transglycosylase activity
AM435_RS07180	COG0741	lytic transglycosylase activity
AM435_RS07185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM435_RS07225	COG0583	DNA-binding transcription factor activity
AM435_RS07230	COG1279	arginine transmembrane transporter activity
AM435_RS07250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM435_RS07255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM435_RS07260	COG0006	proline dipeptidase activity
AM435_RS07295	COG2194	sulfuric ester hydrolase activity
AM435_RS07345	COG0739	heme binding
AM435_RS07675	COG0512	Glutamine amidotransferase of anthranilate synthase
AM435_RS07680	COG0308	aminopeptidase N
AM435_RS07710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM435_RS07720	COG0302	gtp cyclohydrolase
AM435_RS07745	COG3739	integral membrane protein
AM435_RS07760	COG1169	isochorismate synthase
AM435_RS07770	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM435_RS07775	COG1132	(ABC) transporter
AM435_RS07780	COG1132	(ABC) transporter
AM435_RS07795	COG1535	isochorismatase
AM435_RS07795	COG3433	isochorismatase activity
AM435_RS07800	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM435_RS07805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM435_RS07815	COG4774	siderophore transport
AM435_RS07820	COG4607	ABC-type enterochelin transport system periplasmic component
AM435_RS07825	COG4604	ABC transporter, ATP-binding protein
AM435_RS07830	COG4605	iron ion homeostasis
AM435_RS07835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM435_RS07840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM435_RS07855	COG2964	Protein conserved in bacteria
AM435_RS07865	COG1741	Belongs to the pirin family
AM435_RS07885	COG1309	transcriptional regulator
AM435_RS07895	COG4948	Mandelate Racemase Muconate Lactonizing
AM435_RS07900	COG2814	Major facilitator Superfamily
AM435_RS07935	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM435_RS07935	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM435_RS07940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM435_RS07945	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS07955	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM435_RS07970	COG0583	DNA-binding transcription factor activity
AM435_RS07975	COG1113	amino acid transport
AM435_RS07995	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AM435_RS07995	COG2508	Transcriptional regulator
AM435_RS08035	COG2879	small protein
AM435_RS08040	COG1966	Carbon starvation protein
AM435_RS08085	COG1067	ATP-dependent peptidase activity
AM435_RS08090	COG0583	DNA-binding transcription factor activity
AM435_RS08115	COG1686	Belongs to the peptidase S11 family
AM435_RS08120	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM435_RS08155	COG0616	signal peptide processing
AM435_RS08160	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM435_RS08170	COG0573	inorganic phosphate transmembrane transporter activity
AM435_RS08175	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM435_RS08180	COG1113	amino acid transport
AM435_RS08185	COG3961	Belongs to the TPP enzyme family
AM435_RS08190	COG1522	sequence-specific DNA binding
AM435_RS08200	COG0076	glutamate decarboxylase activity
AM435_RS08205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM435_RS08215	COG1309	transcriptional regulator
AM435_RS08230	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM435_RS08265	COG0352	thiamine-phosphate diphosphorylase activity
AM435_RS08290	COG0612	Peptidase, M16
AM435_RS08300	COG1823	symporter activity
AM435_RS08305	COG0583	DNA-binding transcription factor activity
AM435_RS08310	COG0477	Major facilitator Superfamily
AM435_RS08335	COG1187	pseudouridine synthase activity
AM435_RS08350	COG1686	Belongs to the peptidase S11 family
AM435_RS08355	COG1252	NADH dehydrogenase
AM435_RS08365	COG0415	Belongs to the DNA photolyase family
AM435_RS08380	COG1215	transferase activity, transferring glycosyl groups
AM435_RS08410	COG2070	2-Nitropropane dioxygenase
AM435_RS08465	COG0556	nucleotide-excision repair
AM435_RS08485	COG0436	Aminotransferase
AM435_RS08535	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM435_RS08540	COG1381	Involved in DNA repair and RecF pathway recombination
AM435_RS08550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM435_RS08565	COG0681	Belongs to the peptidase S26 family
AM435_RS08580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM435_RS08600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM435_RS08605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM435_RS08610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM435_RS08620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM435_RS08625	COG4208	sulfate ABC transporter
AM435_RS08630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM435_RS08635	COG0583	DNA-binding transcription factor activity
AM435_RS08640	COG4625	pathogenesis
AM435_RS08655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM435_RS08670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM435_RS08680	COG1051	belongs to the nudix hydrolase family
AM435_RS08680	COG1056	cytidyltransferase-related domain
AM435_RS08685	COG1024	Enoyl-CoA hydratase
AM435_RS08695	COG2814	Major facilitator Superfamily
AM435_RS08700	COG0047	phosphoribosylformylglycinamidine synthase activity
AM435_RS08700	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM435_RS08720	COG1473	amidohydrolase
AM435_RS08725	COG0824	Thioesterase
AM435_RS08745	COG0823	Involved in the tonB-independent uptake of proteins
AM435_RS08765	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM435_RS08810	COG0628	permease
AM435_RS08820	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM435_RS08825	COG0596	Alpha beta hydrolase
AM435_RS08830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM435_RS08830	COG0616	signal peptide processing
AM435_RS08840	COG0658	competence protein
AM435_RS08840	COG2333	competence protein COMEC
AM435_RS08845	COG1136	(ABC) transporter
AM435_RS08850	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM435_RS08880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM435_RS08900	COG0463	Glycosyl transferase, family 2
AM435_RS08930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM435_RS08935	COG1280	lysine exporter protein (LysE YggA)
AM435_RS08945	COG0019	diaminopimelate decarboxylase activity
AM435_RS08955	COG1113	amino acid transport
AM435_RS08970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM435_RS08980	COG3339	Conserved Protein
AM435_RS08985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM435_RS08990	COG0243	molybdopterin cofactor binding
AM435_RS08995	COG1929	Belongs to the glycerate kinase type-1 family
AM435_RS09010	COG0778	Nitroreductase
AM435_RS09035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM435_RS09050	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM435_RS09075	COG0741	lytic transglycosylase activity
AM435_RS09095	COG0584	glycerophosphoryl diester phosphodiesterase
AM435_RS09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM435_RS09125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM435_RS09130	COG1597	lipid kinase activity
AM435_RS09145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM435_RS09150	COG0477	Major facilitator Superfamily
AM435_RS09200	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM435_RS09205	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM435_RS09230	COG0505	Belongs to the CarA family
AM435_RS09250	COG0589	response to stress
AM435_RS09265	COG2843	Capsule synthesis protein
AM435_RS09285	COG2321	neutral zinc metallopeptidase
AM435_RS09290	COG2354	Protein conserved in bacteria
AM435_RS09310	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM435_RS09335	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM435_RS09340	COG1053	succinate dehydrogenase
AM435_RS09345	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM435_RS09350	COG2009	succinate dehydrogenase
AM435_RS09390	COG2921	Belongs to the UPF0250 family
AM435_RS09395	COG0321	lipoyl(octanoyl) transferase activity
AM435_RS09410	COG0531	amino acid
AM435_RS09420	COG1733	regulation of RNA biosynthetic process
AM435_RS09425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM435_RS09430	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM435_RS09430	COG1648	precorrin-2 dehydrogenase activity
AM435_RS09445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM435_RS09475	COG0671	phosphoesterase, PA-phosphatase related
AM435_RS09480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM435_RS09490	COG1538	Outer membrane efflux protein
AM435_RS09495	COG0393	Putative heavy-metal-binding
AM435_RS09500	COG0393	Putative heavy-metal-binding
AM435_RS09510	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS09520	COG0525	valine-tRNA ligase activity
AM435_RS09540	COG0583	DNA-binding transcription factor activity
AM435_RS09550	COG0004	ammonium transporteR
AM435_RS09560	COG0642	Histidine kinase
AM435_RS09565	COG0745	RESPONSE REGULATOR receiver
AM435_RS09570	COG2194	sulfuric ester hydrolase activity
AM435_RS09590	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM435_RS09605	COG2315	Protein conserved in bacteria
AM435_RS09610	COG0142	geranyltranstransferase activity
AM435_RS09615	COG2828	Protein conserved in bacteria
AM435_RS09620	COG1113	amino acid transport
AM435_RS09630	COG0582	viral genome integration into host DNA
AM435_RS09840	COG5410	chromosome segregation
AM435_RS10035	COG2207	Transcriptional regulator
AM435_RS10060	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM435_RS10070	COG0560	Phosphoserine phosphatase
AM435_RS10080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM435_RS10090	COG1530	ribonuclease E activity
AM435_RS10095	COG0424	maF-like protein
AM435_RS10100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM435_RS10105	COG1792	Involved in formation and maintenance of cell shape
AM435_RS10110	COG1077	Cell shape determining protein MreB Mrl
AM435_RS10115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM435_RS10125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM435_RS10155	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM435_RS10160	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM435_RS10165	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM435_RS10170	COG1115	amino acid carrier protein
AM435_RS10190	COG2814	Major facilitator Superfamily
AM435_RS10195	COG1289	transmembrane transporter activity
AM435_RS10205	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM435_RS10245	COG1376	ErfK ybiS ycfS ynhG family protein
AM435_RS10250	COG2832	Protein of unknown function (DUF454)
AM435_RS10260	COG5510	response to toxic substance
AM435_RS10280	COG0840	transmembrane signaling receptor activity
AM435_RS10320	COG3422	double-strand break repair
AM435_RS10325	COG2824	Alkylphosphonate utilization operon protein PhnA
AM435_RS10330	COG3189	MarR family transcriptional regulator
AM435_RS10340	COG0354	folic acid binding
AM435_RS10345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM435_RS10360	COG1902	pentaerythritol trinitrate reductase activity
AM435_RS10365	COG4772	TonB-dependent receptor
AM435_RS10370	COG2094	Belongs to the DNA glycosylase MPG family
AM435_RS10395	COG1217	gtp-binding protein TYPA
AM435_RS10400	COG2233	PERMEase
AM435_RS10410	COG0833	amino acid
AM435_RS10415	COG1690	Belongs to the RtcB family
AM435_RS10425	COG2885	chlorophyll binding
AM435_RS10425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM435_RS10435	COG0183	Belongs to the thiolase family
AM435_RS10455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM435_RS10475	COG2207	Transcriptional regulator
AM435_RS10480	COG0183	Belongs to the thiolase family
AM435_RS10510	COG1272	protein, Hemolysin III
AM435_RS10515	COG0477	Major facilitator Superfamily
AM435_RS10530	COG0450	alkyl hydroperoxide reductase
AM435_RS10550	COG0285	dihydrofolate synthase activity
AM435_RS10600	COG2096	Adenosyltransferase
AM435_RS10620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM435_RS10625	COG0745	RESPONSE REGULATOR receiver
AM435_RS10630	COG2205	protein histidine kinase activity
AM435_RS10640	COG1960	acyl-CoA dehydrogenase activity
AM435_RS10645	COG1960	acyl-CoA dehydrogenase activity
AM435_RS10650	COG0583	DNA-binding transcription factor activity
AM435_RS10655	COG0625	glutathione transferase activity
AM435_RS10740	COG0438	transferase activity, transferring glycosyl groups
AM435_RS10745	COG0463	Glycosyl transferase, family 2
AM435_RS10750	COG0726	polysaccharide deacetylase
AM435_RS10770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM435_RS10775	COG2205	protein histidine kinase activity
AM435_RS10820	COG1862	Preprotein translocase
AM435_RS10830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM435_RS10835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM435_RS10845	COG3781	membrane
AM435_RS10850	COG0613	PHP domain protein
AM435_RS10860	COG2350	Protein conserved in bacteria
AM435_RS10890	COG1607	acyl-coa hydrolase
AM435_RS10970	COG1408	metallophosphoesterase
AM435_RS10975	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM435_RS11005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM435_RS11010	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM435_RS11025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM435_RS11035	COG2969	positive regulation of protein catabolic process
AM435_RS11055	COG1960	acyl-CoA dehydrogenase activity
AM435_RS11060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM435_RS11075	COG1309	transcriptional regulator
AM435_RS11080	COG1960	acyl-CoA dehydrogenase activity
AM435_RS11125	COG1183	phosphatidylcholine synthase activity
AM435_RS11130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM435_RS11160	COG0739	heme binding
AM435_RS11160	COG0741	lytic transglycosylase activity
AM435_RS11160	COG1196	nuclear chromosome segregation
AM435_RS11170	COG1702	phosphate starvation-inducible protein PhoH
AM435_RS11205	COG1295	ribonuclease BN
AM435_RS11210	COG0697	spore germination
AM435_RS11215	COG2169	Transcriptional regulator
AM435_RS11220	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM435_RS11265	COG0557	exoribonuclease II activity
AM435_RS11270	COG0339	signal peptide processing
AM435_RS11275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM435_RS11305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM435_RS11310	COG1960	acyl-CoA dehydrogenase activity
AM435_RS11465	COG0626	cystathionine gamma-synthase activity
AM435_RS11470	COG0433	COG0433 Predicted ATPase
AM435_RS11475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM435_RS11475	COG1017	nitric oxide dioxygenase activity
AM435_RS11480	COG1959	2 iron, 2 sulfur cluster binding
AM435_RS11495	COG1301	dicarboxylic acid transport
AM435_RS11500	COG1946	Acyl-CoA thioesterase
AM435_RS11520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM435_RS11525	COG1040	competence protein
AM435_RS11530	COG0494	nUDIX hydrolase
AM435_RS11540	COG0598	Magnesium transport protein CorA
AM435_RS11550	COG2854	intermembrane phospholipid transfer
AM435_RS11560	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM435_RS11565	COG1127	ABC transporter
AM435_RS11575	COG0513	Belongs to the DEAD box helicase family
AM435_RS11595	COG0408	coproporphyrinogen oxidase activity
AM435_RS11610	COG1960	acyl-CoA dehydrogenase activity
AM435_RS11620	COG1983	PspC domain protein
AM435_RS11625	COG0517	IMP dehydrogenase activity
AM435_RS11670	COG0583	DNA-binding transcription factor activity
AM435_RS11710	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS11720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM435_RS11725	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM435_RS11730	COG0833	amino acid
AM435_RS11760	COG1192	Involved in chromosome partitioning
AM435_RS11765	COG0628	permease
AM435_RS11775	COG1289	transmembrane transporter activity
AM435_RS11790	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM435_RS11795	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM435_RS11805	COG0277	FAD linked oxidase domain protein
AM435_RS11810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM435_RS11835	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM435_RS11840	COG5380	lipid catabolic process
AM435_RS11860	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM435_RS11910	COG0194	GDP metabolic process
AM435_RS11925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM435_RS11950	COG3307	-O-antigen
AM435_RS11970	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM435_RS11975	COG1704	LemA family
AM435_RS11985	COG0493	'glutamate synthase
AM435_RS11990	COG0067	glutamate synthase
AM435_RS11990	COG0069	glutamate synthase activity
AM435_RS11990	COG0070	glutamate synthase
AM435_RS12040	COG2226	methyltransferase
AM435_RS12055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM435_RS12060	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM435_RS12105	COG0833	amino acid
AM435_RS12165	COG0488	(ABC) transporter
AM435_RS12170	COG2873	o-acetylhomoserine
AM435_RS12175	COG4221	oxidoreductase activity
AM435_RS12180	COG0659	secondary active sulfate transmembrane transporter activity
AM435_RS12205	COG0427	acetyl-CoA hydrolase
AM435_RS12235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM435_RS12275	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM435_RS12330	COG2207	Transcriptional regulator
AM435_RS12335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AM435_RS12350	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM435_RS12360	COG1733	regulation of RNA biosynthetic process
AM435_RS12375	COG1733	regulation of RNA biosynthetic process
AM435_RS12405	COG0667	Aldo Keto reductase
AM435_RS12430	COG0583	DNA-binding transcription factor activity
AM435_RS12435	COG2814	Major facilitator Superfamily
AM435_RS12465	COG1335	isochorismatase
AM435_RS12475	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS12480	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM435_RS12490	COG1113	amino acid transport
AM435_RS12500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM435_RS12515	COG2814	Major facilitator Superfamily
AM435_RS12525	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM435_RS12525	COG0352	thiamine-phosphate diphosphorylase activity
AM435_RS12525	COG0351	phosphomethylpyrimidine kinase
AM435_RS12545	COG1309	transcriptional regulator
AM435_RS12550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM435_RS12565	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM435_RS12575	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM435_RS12580	COG3162	membrane
AM435_RS12585	COG0784	Response regulator, receiver
AM435_RS12585	COG2198	Histidine kinase
AM435_RS12585	COG2205	protein histidine kinase activity
AM435_RS12610	COG1522	sequence-specific DNA binding
AM435_RS12615	COG1335	isochorismatase
AM435_RS12620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM435_RS12630	COG0668	transmembrane transport
AM435_RS12635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM435_RS12640	COG1519	Transferase
AM435_RS12645	COG1902	pentaerythritol trinitrate reductase activity
AM435_RS12665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM435_RS12690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM435_RS12690	COG0426	domain, Protein
AM435_RS12695	COG4774	siderophore transport
AM435_RS12700	COG2119	membrane
AM435_RS12710	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM435_RS12720	COG4942	peptidase
AM435_RS12735	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM435_RS12745	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM435_RS12765	COG0189	ligase activity
AM435_RS12795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM435_RS12835	COG0708	Exodeoxyribonuclease III
AM435_RS12840	COG1393	Belongs to the ArsC family
AM435_RS12895	COG2233	PERMEase
AM435_RS12905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM435_RS12915	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM435_RS12925	COG3150	esterase
AM435_RS12950	COG3179	chitinase
AM435_RS12965	COG2918	glutathione biosynthetic process
AM435_RS12980	COG2733	membrane
AM435_RS12985	COG0436	Aminotransferase
AM435_RS12990	COG0534	Mate efflux family protein
AM435_RS13050	COG0753	catalase activity
AM435_RS13100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM435_RS13105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM435_RS13115	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM435_RS13120	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM435_RS13125	COG0546	phosphoglycolate phosphatase activity
AM435_RS13135	COG0010	Belongs to the arginase family
AM435_RS13165	COG2188	Transcriptional regulator
AM435_RS13175	COG0523	cobalamin synthesis protein
AM435_RS13185	COG1113	amino acid transport
AM435_RS13195	COG0625	glutathione transferase activity
AM435_RS13215	COG1683	Conserved Protein
AM435_RS13220	COG0534	Mate efflux family protein
AM435_RS13225	COG0385	Bile acid
AM435_RS13230	COG1335	isochorismatase
AM435_RS13235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM435_RS13260	COG2116	formate transmembrane transporter activity
AM435_RS13265	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM435_RS13270	COG2133	pyrroloquinoline quinone binding
AM435_RS13275	COG2983	Belongs to the UPF0260 family
AM435_RS13295	COG1194	a g-specific adenine glycosylase
AM435_RS13310	COG2818	Glycosylase
AM435_RS13315	COG1064	alcohol dehydrogenase
AM435_RS13320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM435_RS13335	COG0583	DNA-binding transcription factor activity
AM435_RS13340	COG0656	L-ascorbic acid biosynthetic process
AM435_RS13345	COG2814	Major facilitator Superfamily
AM435_RS13380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM435_RS13395	COG2233	PERMEase
AM435_RS13435	COG0733	neurotransmitter:sodium symporter activity
AM435_RS13480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM435_RS13485	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM435_RS13490	COG0596	Alpha beta hydrolase
AM435_RS13515	COG0488	(ABC) transporter
AM435_RS13520	COG0586	Pfam SNARE associated Golgi protein
AM435_RS13530	COG0187	DNA topoisomerase II activity
AM435_RS13540	COG0592	DNA-directed DNA polymerase activity
AM435_RS13565	COG0706	membrane insertase activity
AM435_RS13580	COG1230	cation diffusion facilitator family transporter
AM435_RS13585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM435_RS13600	COG0402	S-adenosylhomocysteine deaminase activity
AM435_RS13610	COG0754	glutathionylspermidine amidase activity
AM435_RS13625	COG0861	Integral membrane protein TerC family
AM435_RS13630	COG0671	phosphoesterase, PA-phosphatase related
AM435_RS13640	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM435_RS13660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM435_RS13665	COG2951	lytic endotransglycosylase activity
AM435_RS13715	COG0657	acetylesterase activity
AM435_RS13720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM435_RS13760	COG1047	Peptidyl-prolyl cis-trans
AM435_RS13770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM435_RS13775	COG0196	riboflavin kinase activity
AM435_RS13785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM435_RS13790	COG1309	transcriptional regulator
AM435_RS13795	COG1116	anion transmembrane transporter activity
AM435_RS13800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM435_RS13805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM435_RS13810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM435_RS13815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM435_RS13835	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS13840	COG0546	phosphoglycolate phosphatase activity
AM435_RS13900	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM435_RS13905	COG0728	peptidoglycan biosynthetic process
AM435_RS13930	COG1596	polysaccharide export
AM435_RS13935	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM435_RS13990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AM435_RS13995	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM435_RS14000	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM435_RS14015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM435_RS14020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM435_RS14030	COG2186	Transcriptional regulator
AM435_RS14040	COG0277	FAD linked oxidase domain protein
AM435_RS14045	COG1448	Aminotransferase
AM435_RS14055	COG1802	Transcriptional regulator
AM435_RS14070	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM435_RS14090	COG1051	belongs to the nudix hydrolase family
AM435_RS14120	COG0564	pseudouridine synthase activity
AM435_RS14160	COG0251	oxidation-reduction process
AM435_RS14165	COG1113	amino acid transport
AM435_RS14170	COG1113	amino acid transport
AM435_RS14190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM435_RS14195	COG1960	acyl-CoA dehydrogenase activity
AM435_RS14200	COG1024	Enoyl-CoA hydratase
AM435_RS14205	COG1024	Enoyl-CoA hydratase
AM435_RS14210	COG0477	Major facilitator Superfamily
AM435_RS14215	COG3916	Acyl-homoserine-lactone synthase
AM435_RS14225	COG2197	response regulator
AM435_RS14240	COG1960	acyl-CoA dehydrogenase activity
AM435_RS14245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM435_RS14245	COG3321	synthase
AM435_RS14245	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM435_RS14245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM435_RS14265	COG2267	carboxylic ester hydrolase activity
AM435_RS14285	COG0271	Belongs to the BolA IbaG family
AM435_RS14295	COG1192	Involved in chromosome partitioning
AM435_RS14310	COG0586	Pfam SNARE associated Golgi protein
AM435_RS14315	COG2259	Doxx family
AM435_RS14320	COG4399	Belongs to the UPF0754 family
AM435_RS14325	COG0519	Catalyzes the synthesis of GMP from XMP
AM435_RS14325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM435_RS14370	COG0281	malic enzyme
AM435_RS14380	COG2837	iron assimilation
AM435_RS14385	COG1280	lysine exporter protein (LysE YggA)
AM435_RS14390	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM435_RS14395	COG1121	(ABC) transporter
AM435_RS14460	COG0386	Belongs to the glutathione peroxidase family
AM435_RS14475	COG1309	transcriptional regulator
AM435_RS14480	COG0697	spore germination
AM435_RS14490	COG0758	DNA mediated transformation
AM435_RS14525	COG1309	transcriptional regulator
AM435_RS14560	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM435_RS14570	COG0655	NAD(P)H dehydrogenase (quinone) activity
AM435_RS14605	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM435_RS14615	COG2814	Major facilitator Superfamily
AM435_RS14625	COG1253	flavin adenine dinucleotide binding
AM435_RS14635	COG2860	membrane
AM435_RS14640	COG0477	Major facilitator Superfamily
AM435_RS14650	COG0318	PFAM AMP-dependent synthetase and ligase
AM435_RS14665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM435_RS14680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM435_RS14690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM435_RS14695	COG0606	chelatase, subunit chli
AM435_RS14725	COG0589	response to stress
AM435_RS14730	COG0659	secondary active sulfate transmembrane transporter activity
AM435_RS14800	COG0606	chelatase, subunit chli
AM435_RS14810	COG0347	Belongs to the P(II) protein family
AM435_RS14815	COG0004	ammonium transporteR
AM435_RS14825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM435_RS14825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM435_RS14865	COG0795	lipopolysaccharide-transporting ATPase activity
AM435_RS14870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM435_RS14875	COG0793	Belongs to the peptidase S41A family
AM435_RS14890	COG2197	response regulator
AM435_RS14900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM435_RS14910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM435_RS14915	COG4974	Belongs to the 'phage' integrase family
AM435_RS14940	COG0772	Belongs to the SEDS family
AM435_RS14945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM435_RS14950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM435_RS14955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM435_RS14980	COG0697	spore germination
AM435_RS14985	COG1538	Outer membrane efflux protein
AM435_RS15005	COG3275	phosphorelay sensor kinase activity
AM435_RS15015	COG0181	hydroxymethylbilane synthase activity
AM435_RS15060	COG1716	ATPase activity
AM435_RS15065	COG0546	phosphoglycolate phosphatase activity
AM435_RS15160	COG0596	Alpha beta hydrolase
AM435_RS15165	COG2056	Na+-H+ antiporter family
AM435_RS15180	COG0326	Molecular chaperone. Has ATPase activity
AM435_RS15195	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AM435_RS15255	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM435_RS15305	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM435_RS15310	COG2169	Transcriptional regulator
AM435_RS15310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM435_RS15340	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM435_RS15350	COG0497	DNA recombination
AM435_RS15365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM435_RS15375	COG0237	dephospho-CoA kinase activity
AM435_RS15425	COG0195	Participates in both transcription termination and antitermination
AM435_RS15440	COG1320	monovalent cation:proton antiporter activity
AM435_RS15445	COG2212	antiporter activity
AM435_RS15450	COG1863	multisubunit Na H antiporter MnhE subunit
AM435_RS15455	COG0651	ATP synthesis coupled electron transport
AM435_RS15460	COG1006	Multisubunit Na H antiporter MnhC subunit
AM435_RS15465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM435_RS15465	COG2111	Na H antiporter
AM435_RS15480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM435_RS15485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM435_RS15500	COG2226	methyltransferase
AM435_RS15520	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM435_RS15525	COG1074	ATP-dependent DNA helicase activity
AM435_RS15530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM435_RS15535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM435_RS15550	COG0598	Magnesium transport protein CorA
AM435_RS15555	COG0789	Transcriptional regulator
AM435_RS15560	COG0484	heat shock protein binding
AM435_RS15570	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AM435_RS15575	COG0475	glutathione-regulated potassium exporter activity
AM435_RS15575	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM435_RS15580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM435_RS15600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM435_RS15610	COG4535	Mg2 and Co2 transporter CorC
AM435_RS15615	COG0425	Belongs to the sulfur carrier protein TusA family
AM435_RS15620	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM435_RS15620	COG0644	oxidoreductase
AM435_RS15630	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM435_RS15645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM435_RS15650	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM435_RS15690	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM435_RS15705	COG0534	Mate efflux family protein
AM435_RS15715	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM435_RS15720	COG4221	oxidoreductase activity
AM435_RS15725	COG0583	DNA-binding transcription factor activity
AM435_RS15740	COG0318	PFAM AMP-dependent synthetase and ligase
AM435_RS15745	COG1530	ribonuclease E activity
AM435_RS15760	COG0546	phosphoglycolate phosphatase activity
AM435_RS15765	COG2378	regulation of single-species biofilm formation
AM435_RS15770	COG0625	glutathione transferase activity
AM435_RS15780	COG0583	DNA-binding transcription factor activity
AM435_RS15845	COG0473	3-isopropylmalate dehydrogenase activity
AM435_RS15905	COG1301	dicarboxylic acid transport
AM435_RS15915	COG1560	Kdo2-lipid A biosynthetic process
AM435_RS15920	COG1280	lysine exporter protein (LysE YggA)
AM435_RS15925	COG0488	(ABC) transporter
AM435_RS15930	COG2900	Belongs to the SlyX family
AM435_RS15940	COG1733	regulation of RNA biosynthetic process
AM435_RS15965	COG0210	DNA helicase
AM435_RS15970	COG0724	RNA recognition motif
AM435_RS15990	COG4651	solute:proton antiporter activity
AM435_RS15990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM435_RS16015	COG0788	formyltetrahydrofolate deformylase activity
AM435_RS16115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM435_RS16115	COG2813	Specifically methylates the guanine in position
AM435_RS16125	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM435_RS16135	COG4774	siderophore transport
AM435_RS16145	COG0740	serine-type endopeptidase activity
AM435_RS16165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM435_RS16165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM435_RS16170	COG0280	phosphate acetyltransferase
AM435_RS16170	COG0857	belongs to the CobB CobQ family
AM435_RS16175	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM435_RS16185	COG0800	Aldolase
AM435_RS16195	COG3265	gluconokinase activity
AM435_RS16200	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS16210	COG2267	carboxylic ester hydrolase activity
AM435_RS16225	COG0793	Belongs to the peptidase S41A family
AM435_RS16260	COG1426	Protein conserved in bacteria
AM435_RS16305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM435_RS16315	COG0318	PFAM AMP-dependent synthetase and ligase
AM435_RS16330	COG2986	histidine ammonia-lyase
AM435_RS16370	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS16375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AM435_RS16395	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM435_RS16405	COG1162	GTPase activity
AM435_RS16410	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM435_RS16425	COG1538	Outer membrane efflux protein
AM435_RS16430	COG1136	(ABC) transporter
AM435_RS16430	COG0577	efflux transmembrane transporter activity
AM435_RS16470	COG0028	Belongs to the TPP enzyme family
AM435_RS16475	COG0440	acetolactate synthase activity
AM435_RS16510	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM435_RS16525	COG0084	hydrolase, TatD family'
AM435_RS16540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM435_RS16550	COG0583	DNA-binding transcription factor activity
AM435_RS16560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM435_RS16565	COG2814	Major facilitator Superfamily
AM435_RS16575	COG0697	spore germination
AM435_RS16605	COG3622	Belongs to the hyi family
AM435_RS16610	COG2084	Dehydrogenase
AM435_RS16615	COG1024	Enoyl-CoA hydratase
AM435_RS16620	COG0784	Response regulator, receiver
AM435_RS16620	COG5002	protein histidine kinase activity
AM435_RS16620	COG2205	protein histidine kinase activity
AM435_RS16640	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM435_RS16650	COG3956	TIGRFAM MazG family protein
AM435_RS16655	COG1555	photosystem II stabilization
AM435_RS16660	COG0617	tRNA 3'-terminal CCA addition
AM435_RS16665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM435_RS16685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM435_RS16690	COG3028	Belongs to the UPF0307 family
AM435_RS16695	COG0318	PFAM AMP-dependent synthetase and ligase
AM435_RS16715	COG0625	glutathione transferase activity
AM435_RS16720	COG1238	metal cluster binding
AM435_RS16760	COG0072	phenylalanine-tRNA ligase activity
AM435_RS16790	COG0248	Ppx GppA phosphatase
AM435_RS16800	COG0037	tRNA processing
AM435_RS16840	COG1764	response to oxidative stress
AM435_RS16845	COG1846	Transcriptional regulator
AM435_RS16855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM435_RS16915	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM435_RS16920	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM435_RS16925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM435_RS16935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM435_RS16980	COG1214	PFAM Peptidase M22, glycoprotease
AM435_RS17005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM435_RS17010	COG0561	phosphatase activity
AM435_RS17020	COG2132	Multicopper oxidase
AM435_RS17025	COG3667	copper resistance
AM435_RS17040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM435_RS17045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM435_RS17050	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM435_RS17080	COG1063	alcohol dehydrogenase
AM435_RS17085	COG0583	DNA-binding transcription factor activity
AM435_RS17090	COG1960	acyl-CoA dehydrogenase activity
AM435_RS17095	COG2814	Major facilitator Superfamily
AM435_RS17100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM435_RS17110	COG1053	succinate dehydrogenase
AM435_RS17115	COG0583	DNA-binding transcription factor activity
AM435_RS17135	COG0583	DNA-binding transcription factor activity
AM435_RS17165	COG0583	DNA-binding transcription factor activity
AM435_RS17180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM435_RS17210	COG0384	phenazine biosynthesis protein PhzF
AM435_RS17230	COG4993	Dehydrogenase
AM435_RS17300	COG2826	transposase and inactivated derivatives, IS30 family
AM435_RS17310	COG2826	transposase and inactivated derivatives, IS30 family
AM435_RS17320	COG2205	protein histidine kinase activity
AM435_RS17330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM435_RS17350	COG0745	RESPONSE REGULATOR receiver
AM435_RS17390	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM435_RS17420	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM435_RS17425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM435_RS17445	COG0583	DNA-binding transcription factor activity
AM435_RS17465	COG0668	transmembrane transport
AM435_RS17475	COG2081	HI0933 family
AM435_RS17480	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM435_RS17510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM435_RS17510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM435_RS17520	COG0489	protein tyrosine kinase activity
AM435_RS17580	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM435_RS17590	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM435_RS17605	COG0730	response to heat
AM435_RS17615	COG1196	nuclear chromosome segregation
AM435_RS17635	COG2223	nitrite transmembrane transporter activity
AM435_RS17640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM435_RS17660	COG2226	methyltransferase
AM435_RS17660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM435_RS17660	COG0596	Alpha beta hydrolase
AM435_RS17675	COG4106	trans-aconitate 2-methyltransferase activity
AM435_RS17690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM435_RS17695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM435_RS17700	COG0009	L-threonylcarbamoyladenylate synthase
AM435_RS17705	COG3101	peptidyl-lysine hydroxylation
AM435_RS17710	COG1399	metal-binding, possibly nucleic acid-binding protein
AM435_RS17735	COG1652	LysM domain
AM435_RS17740	COG0352	thiamine-phosphate diphosphorylase activity
AM435_RS17740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM435_RS17740	COG0351	phosphomethylpyrimidine kinase
AM435_RS17750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM435_RS17780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM435_RS17810	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM435_RS17825	COG0358	DNA primase activity
AM435_RS17835	COG0564	pseudouridine synthase activity
AM435_RS17860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM435_RS17880	COG0583	DNA-binding transcription factor activity
AM435_RS17885	COG0473	3-isopropylmalate dehydrogenase activity
AM435_RS17895	COG0657	acetylesterase activity
AM435_RS17905	COG1012	belongs to the aldehyde dehydrogenase family
AM435_RS17925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM435_RS17925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM435_RS17940	COG1981	membrane
AM435_RS17985	COG0456	acetyltransferase
AM435_RS17995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM435_RS18005	COG0492	ferredoxin-NADP+ reductase activity
AM435_RS18010	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM435_RS18010	COG1674	ftsk spoiiie
AM435_RS18015	COG1280	lysine exporter protein (LysE YggA)
AM435_RS18035	COG2894	cell division
AM435_RS18050	COG0204	Acyl-transferase
AM435_RS18055	COG2885	chlorophyll binding
AM435_RS18060	COG0210	DNA helicase
AM435_RS18070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM435_RS18085	COG0121	glutamine amidotransferase
AM435_RS18110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM435_RS18115	COG0735	belongs to the Fur family
AM435_RS18140	COG0420	3'-5' exonuclease activity
AM435_RS18160	COG1090	epimerase
AM435_RS18175	COG2050	protein possibly involved in aromatic compounds catabolism
AM435_RS18185	COG2814	Major facilitator Superfamily
AM435_RS18190	COG0405	Gamma-glutamyltransferase
AM435_RS18340	COG5410	chromosome segregation
AM435_RS18460	COG1598	PFAM Uncharacterised protein family UPF0150
AM435_RS18475	COG0741	lytic transglycosylase activity
AM435_RS18475	COG0739	heme binding
AM435_RS18475	COG1196	nuclear chromosome segregation
AM435_RS18540	COG0477	Major facilitator Superfamily
AM435_RS18545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM435_RS18555	COG1595	DNA-templated transcription, initiation
AM435_RS18610	COG0531	amino acid
AM435_RS18615	COG2040	homocysteine
AM435_RS18640	COG1309	transcriptional regulator
AM435_RS18645	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM435_RS18650	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM435_RS18660	COG1607	acyl-coa hydrolase
AM435_RS18670	COG0523	cobalamin synthesis protein
AM435_RS18680	COG4681	YaeQ
AM435_RS18690	COG1649	PFAM Uncharacterised BCR, COG1649
AM435_RS18690	COG0726	polysaccharide deacetylase
AM435_RS18695	COG1215	transferase activity, transferring glycosyl groups
AM435_RS18705	COG1024	Enoyl-CoA hydratase
AM435_RS18720	COG1414	Transcriptional regulator
AM435_RS18740	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS18750	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM435_RS18755	COG2271	Major facilitator Superfamily
AM435_RS18765	COG2267	carboxylic ester hydrolase activity
AM435_RS18770	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS18785	COG0028	Belongs to the TPP enzyme family
AM435_RS18795	COG0477	Major facilitator Superfamily
AM435_RS18800	COG0242	peptide deformylase activity
AM435_RS18805	COG2066	Belongs to the glutaminase family
AM435_RS18810	COG2207	Transcriptional regulator
AM435_RS18815	COG2223	nitrite transmembrane transporter activity
AM435_RS18835	COG0583	DNA-binding transcription factor activity
AM435_RS18840	COG1028	Short-chain dehydrogenase reductase Sdr
AM435_RS18845	COG2271	Major facilitator Superfamily
AM435_RS18850	COG3959	Transketolase, thiamine diphosphate binding domain
AM435_RS18855	COG3958	Transketolase
AM435_RS18865	COG0306	phosphate transporter
AM435_RS18885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM435_RS18930	COG4181	ATPase activity
AM435_RS18935	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM435_RS18960	COG0583	DNA-binding transcription factor activity
AM435_RS18970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM435_RS18975	COG1773	rubredoxin
AM435_RS19070	COG0804	urea catabolic process
AM435_RS19080	COG0830	nickel cation binding
AM435_RS19095	COG0742	ribosomal rna small subunit methyltransferase
AM435_RS19100	COG0768	penicillin binding
AM435_RS19125	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM435_RS19130	COG2878	Part of a membrane complex involved in electron transport
AM435_RS19135	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM435_RS19145	COG3384	dioxygenase
AM435_RS19170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM435_RS19555	COG0174	glutamine synthetase
AM435_RS19565	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM435_RS19600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM435_RS19605	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM435_RS19610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM435_RS19630	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM435_RS19635	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM435_RS19640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM435_RS19655	COG1960	acyl-CoA dehydrogenase activity
AM435_RS19660	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM435_RS19665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM435_RS19675	COG2223	nitrite transmembrane transporter activity
AM435_RS19685	COG0024	Methionine aminopeptidase
AM435_RS19690	COG0052	Belongs to the universal ribosomal protein uS2 family
AM435_RS19705	COG2207	Transcriptional regulator
AM435_RS19730	COG2951	lytic endotransglycosylase activity
AM435_RS19735	COG0772	Belongs to the SEDS family
AM435_RS19750	COG0842	Transport permease protein
AM435_RS19755	COG1131	(ABC) transporter
AM435_RS19800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM435_RS19815	COG4215	(ABC) transporter
AM435_RS19820	COG4160	amino acid transport
AM435_RS19825	COG4598	ABC transporter
AM435_RS19835	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM435_RS19840	COG0826	peptidase U32
AM435_RS19845	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM435_RS19860	COG1720	tRNA m6t6A37 methyltransferase activity
AM435_RS19870	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM435_RS19885	COG0642	Histidine kinase
AM435_RS19895	COG0494	nUDIX hydrolase
AM435_RS19905	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM435_RS19910	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM435_RS19915	COG3139	Protein of unknown function (DUF1315)
AM435_RS19920	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM435_RS19930	COG1301	dicarboxylic acid transport
AM435_RS19935	COG1960	acyl-CoA dehydrogenase activity
AM435_RS19940	COG2819	hydrolase of the alpha beta superfamily
AM435_RS19950	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM435_RS19960	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM435_RS19965	COG1234	tRNA 3'-trailer cleavage
AM435_RS19995	COG2363	Small membrane protein
AM435_RS20015	COG0513	Belongs to the DEAD box helicase family
AM435_RS20025	COG0778	Nitroreductase
AM435_RS20055	COG1286	toxin biosynthetic process
AM435_RS20080	COG4783	chaperone-mediated protein folding
AM435_RS20085	COG1610	YqeY-like protein
AM435_RS20185	COG3111	PFAM Bacterial OB fold (BOF) protein
AM435_RS20210	COG3243	poly(R)-hydroxyalkanoic acid synthase
AM435_RS20215	COG0786	glutamate:sodium symporter activity
AM435_RS20225	COG2186	Transcriptional regulator
AM435_RS20280	COG0477	Major facilitator Superfamily
AM435_RS20310	COG2985	domain, Protein
AM435_RS20325	COG2995	paraquat-inducible protein a
AM435_RS20330	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM435_RS20330	COG3008	intermembrane lipid transfer
AM435_RS20350	COG1794	racemase activity, acting on amino acids and derivatives
AM435_RS20380	COG1301	dicarboxylic acid transport
AM435_RS20395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM435_RS20400	COG2011	ABC-type metal ion transport system permease component
AM435_RS20405	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM435_RS20410	COG1464	Belongs to the NlpA lipoprotein family
AM435_RS20415	COG0151	Belongs to the GarS family
AM435_RS20420	COG0138	bifunctional purine biosynthesis protein purh
AM435_RS20425	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM435_RS20455	COG2308	Evidence 4 Homologs of previously reported genes of
AM435_RS20465	COG1305	Transglutaminase-like
AM435_RS20475	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM435_RS20480	COG0305	Participates in initiation and elongation during chromosome replication
AM435_RS20505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM435_RS20515	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM435_RS20520	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM435_RS20555	COG1649	PFAM Uncharacterised BCR, COG1649
AM435_RS20555	COG0726	polysaccharide deacetylase
AM435_RS20560	COG1215	transferase activity, transferring glycosyl groups
AM435_RS20565	COG3658	cytochrome
AM435_RS20575	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM435_RS20595	COG0583	DNA-binding transcription factor activity
AM435_RS20615	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM435_RS20620	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM435_RS20635	COG1960	acyl-CoA dehydrogenase activity
AM435_RS20640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM435_RS20645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM435_RS20670	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM435_RS20675	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM435_RS20685	COG2205	protein histidine kinase activity
AM435_RS20690	COG0745	RESPONSE REGULATOR receiver
AM435_RS20695	COG0174	glutamine synthetase
AM435_RS20715	COG0729	surface antigen