locus-tag	class	description
C7R87_RS00015	COG3853	Toxic anion resistance protein (TelA)
C7R87_RS00035	COG1475	DNA binding
C7R87_RS00115	COG1525	nuclease
C7R87_RS00185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7R87_RS00265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7R87_RS00300	COG0741	lytic transglycosylase activity
C7R87_RS00330	COG2826	transposase and inactivated derivatives, IS30 family
C7R87_RS00400	COG0484	heat shock protein binding
C7R87_RS00510	COG0358	DNA primase activity
C7R87_RS00550	COG0194	GDP metabolic process
C7R87_RS00575	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C7R87_RS00630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7R87_RS00675	COG0419	ATPase involved in DNA repair
C7R87_RS00720	COG3173	Aminoglycoside phosphotransferase
C7R87_RS00725	COG0488	(ABC) transporter
C7R87_RS00755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7R87_RS00780	COG0756	dUTP diphosphatase activity
C7R87_RS01025	COG1475	DNA binding
C7R87_RS01030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7R87_RS01140	COG0791	NLP P60 protein
C7R87_RS01180	COG0840	transmembrane signaling receptor activity
C7R87_RS01200	COG5510	response to toxic substance
C7R87_RS01210	COG2832	Protein of unknown function (DUF454)
C7R87_RS01215	COG1376	ErfK ybiS ycfS ynhG family protein
C7R87_RS01255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C7R87_RS01265	COG1289	transmembrane transporter activity
C7R87_RS01270	COG2814	Major facilitator Superfamily
C7R87_RS01290	COG1115	amino acid carrier protein
C7R87_RS01295	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7R87_RS01300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7R87_RS01305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
C7R87_RS01335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7R87_RS01345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
C7R87_RS01350	COG1077	Cell shape determining protein MreB Mrl
C7R87_RS01355	COG1792	Involved in formation and maintenance of cell shape
C7R87_RS01360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7R87_RS01365	COG0424	maF-like protein
C7R87_RS01370	COG1530	ribonuclease E activity
C7R87_RS01380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7R87_RS01390	COG0560	Phosphoserine phosphatase
C7R87_RS01400	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7R87_RS01425	COG2207	Transcriptional regulator
C7R87_RS01620	COG5410	chromosome segregation
C7R87_RS01830	COG0582	viral genome integration into host DNA
C7R87_RS01840	COG1113	amino acid transport
C7R87_RS01845	COG2828	Protein conserved in bacteria
C7R87_RS01850	COG0142	geranyltranstransferase activity
C7R87_RS01855	COG2315	Protein conserved in bacteria
C7R87_RS01870	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7R87_RS01890	COG2194	sulfuric ester hydrolase activity
C7R87_RS01895	COG0745	RESPONSE REGULATOR receiver
C7R87_RS01900	COG0642	Histidine kinase
C7R87_RS01910	COG0004	ammonium transporteR
C7R87_RS01920	COG0583	DNA-binding transcription factor activity
C7R87_RS01940	COG0525	valine-tRNA ligase activity
C7R87_RS01950	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS01960	COG0393	Putative heavy-metal-binding
C7R87_RS01965	COG0393	Putative heavy-metal-binding
C7R87_RS01970	COG1538	Outer membrane efflux protein
C7R87_RS01980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7R87_RS01985	COG0671	phosphoesterase, PA-phosphatase related
C7R87_RS02015	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7R87_RS02030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7R87_RS02030	COG1648	precorrin-2 dehydrogenase activity
C7R87_RS02035	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7R87_RS02040	COG1733	regulation of RNA biosynthetic process
C7R87_RS02050	COG0531	amino acid
C7R87_RS02065	COG0321	lipoyl(octanoyl) transferase activity
C7R87_RS02070	COG2921	Belongs to the UPF0250 family
C7R87_RS02110	COG2009	succinate dehydrogenase
C7R87_RS02115	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C7R87_RS02120	COG1053	succinate dehydrogenase
C7R87_RS02125	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7R87_RS02150	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7R87_RS02170	COG2354	Protein conserved in bacteria
C7R87_RS02175	COG2321	neutral zinc metallopeptidase
C7R87_RS02195	COG2843	Capsule synthesis protein
C7R87_RS02210	COG0589	response to stress
C7R87_RS02230	COG0505	Belongs to the CarA family
C7R87_RS02255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7R87_RS02260	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7R87_RS02310	COG0477	Major facilitator Superfamily
C7R87_RS02315	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7R87_RS02330	COG1597	lipid kinase activity
C7R87_RS02335	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7R87_RS02360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7R87_RS02365	COG0584	glycerophosphoryl diester phosphodiesterase
C7R87_RS02385	COG0741	lytic transglycosylase activity
C7R87_RS02410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7R87_RS02425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7R87_RS02455	COG0778	Nitroreductase
C7R87_RS02470	COG1929	Belongs to the glycerate kinase type-1 family
C7R87_RS02475	COG0243	molybdopterin cofactor binding
C7R87_RS02480	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7R87_RS02485	COG3339	Conserved Protein
C7R87_RS02495	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
C7R87_RS02510	COG1113	amino acid transport
C7R87_RS02520	COG0019	diaminopimelate decarboxylase activity
C7R87_RS02530	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS02535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
C7R87_RS02565	COG0463	Glycosyl transferase, family 2
C7R87_RS02585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7R87_RS02615	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7R87_RS02620	COG1136	(ABC) transporter
C7R87_RS02625	COG2333	competence protein COMEC
C7R87_RS02625	COG0658	competence protein
C7R87_RS02635	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7R87_RS02635	COG0616	signal peptide processing
C7R87_RS02640	COG0596	Alpha beta hydrolase
C7R87_RS02645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7R87_RS02655	COG0628	permease
C7R87_RS02700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7R87_RS02720	COG0823	Involved in the tonB-independent uptake of proteins
C7R87_RS02740	COG0824	Thioesterase
C7R87_RS02745	COG1473	amidohydrolase
C7R87_RS02765	COG0047	phosphoribosylformylglycinamidine synthase activity
C7R87_RS02765	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7R87_RS02770	COG2814	Major facilitator Superfamily
C7R87_RS02780	COG1024	Enoyl-CoA hydratase
C7R87_RS02785	COG1056	cytidyltransferase-related domain
C7R87_RS02785	COG1051	belongs to the nudix hydrolase family
C7R87_RS02795	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7R87_RS02810	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7R87_RS02825	COG4625	pathogenesis
C7R87_RS02830	COG0583	DNA-binding transcription factor activity
C7R87_RS02835	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7R87_RS02840	COG4208	sulfate ABC transporter
C7R87_RS02845	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7R87_RS02855	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7R87_RS02860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7R87_RS02865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7R87_RS02885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7R87_RS02900	COG0681	Belongs to the peptidase S26 family
C7R87_RS02915	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
C7R87_RS02925	COG1381	Involved in DNA repair and RecF pathway recombination
C7R87_RS02930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7R87_RS02980	COG0436	Aminotransferase
C7R87_RS03000	COG0556	nucleotide-excision repair
C7R87_RS03055	COG2070	2-Nitropropane dioxygenase
C7R87_RS03085	COG1215	transferase activity, transferring glycosyl groups
C7R87_RS03100	COG0415	Belongs to the DNA photolyase family
C7R87_RS03110	COG1252	NADH dehydrogenase
C7R87_RS03115	COG1686	Belongs to the peptidase S11 family
C7R87_RS03130	COG1187	pseudouridine synthase activity
C7R87_RS03155	COG0477	Major facilitator Superfamily
C7R87_RS03160	COG0583	DNA-binding transcription factor activity
C7R87_RS03165	COG1823	symporter activity
C7R87_RS03175	COG0612	Peptidase, M16
C7R87_RS03200	COG0352	thiamine-phosphate diphosphorylase activity
C7R87_RS03235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7R87_RS03250	COG1309	transcriptional regulator
C7R87_RS03260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7R87_RS03265	COG0076	glutamate decarboxylase activity
C7R87_RS03275	COG1522	sequence-specific DNA binding
C7R87_RS03280	COG3961	Belongs to the TPP enzyme family
C7R87_RS03285	COG1113	amino acid transport
C7R87_RS03290	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
C7R87_RS03295	COG0573	inorganic phosphate transmembrane transporter activity
C7R87_RS03305	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7R87_RS03310	COG0616	signal peptide processing
C7R87_RS03345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7R87_RS03350	COG1686	Belongs to the peptidase S11 family
C7R87_RS03375	COG0583	DNA-binding transcription factor activity
C7R87_RS03380	COG1067	ATP-dependent peptidase activity
C7R87_RS03425	COG1966	Carbon starvation protein
C7R87_RS03430	COG2879	small protein
C7R87_RS03470	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
C7R87_RS03470	COG2508	Transcriptional regulator
C7R87_RS03490	COG1113	amino acid transport
C7R87_RS03495	COG0583	DNA-binding transcription factor activity
C7R87_RS03510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7R87_RS03520	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS03525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7R87_RS03530	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7R87_RS03530	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C7R87_RS03565	COG2814	Major facilitator Superfamily
C7R87_RS03570	COG4948	Mandelate Racemase Muconate Lactonizing
C7R87_RS03580	COG1309	transcriptional regulator
C7R87_RS03600	COG1741	Belongs to the pirin family
C7R87_RS03610	COG2964	Protein conserved in bacteria
C7R87_RS03625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7R87_RS03630	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7R87_RS03635	COG4605	iron ion homeostasis
C7R87_RS03640	COG4604	ABC transporter, ATP-binding protein
C7R87_RS03645	COG4607	ABC-type enterochelin transport system periplasmic component
C7R87_RS03650	COG4774	siderophore transport
C7R87_RS03660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7R87_RS03665	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7R87_RS03670	COG3433	isochorismatase activity
C7R87_RS03670	COG1535	isochorismatase
C7R87_RS03685	COG1132	(ABC) transporter
C7R87_RS03690	COG1132	(ABC) transporter
C7R87_RS03695	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
C7R87_RS03705	COG1169	isochorismate synthase
C7R87_RS03720	COG3739	integral membrane protein
C7R87_RS03745	COG0302	gtp cyclohydrolase
C7R87_RS03755	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7R87_RS03785	COG0308	aminopeptidase N
C7R87_RS03790	COG0512	Glutamine amidotransferase of anthranilate synthase
C7R87_RS04120	COG0739	heme binding
C7R87_RS04170	COG2194	sulfuric ester hydrolase activity
C7R87_RS04205	COG0006	proline dipeptidase activity
C7R87_RS04210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7R87_RS04215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7R87_RS04235	COG1279	arginine transmembrane transporter activity
C7R87_RS04240	COG0583	DNA-binding transcription factor activity
C7R87_RS04280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7R87_RS04285	COG0741	lytic transglycosylase activity
C7R87_RS04285	COG1388	LysM domain
C7R87_RS04285	COG0741	lytic transglycosylase activity
C7R87_RS04285	COG1388	LysM domain
C7R87_RS04295	COG4174	ABC transporter (Permease)
C7R87_RS04300	COG4239	(ABC) transporter, permease
C7R87_RS04305	COG4172	Belongs to the ABC transporter superfamily
C7R87_RS04325	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7R87_RS04335	COG4251	negative regulation of phosphorylation
C7R87_RS04335	COG3706	GGDEF domain
C7R87_RS04335	COG5001	Diguanylate cyclase
C7R87_RS04335	COG2203	Gaf domain
C7R87_RS04345	COG1902	pentaerythritol trinitrate reductase activity
C7R87_RS04345	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7R87_RS04360	COG4269	membrane
C7R87_RS04385	COG3209	COG3209 Rhs family protein
C7R87_RS04420	COG0531	amino acid
C7R87_RS04440	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS04460	COG1113	amino acid transport
C7R87_RS04470	COG1113	amino acid transport
C7R87_RS04485	COG0697	spore germination
C7R87_RS04490	COG2721	sulfolactate sulfo-lyase activity
C7R87_RS04495	COG2271	Major facilitator Superfamily
C7R87_RS04500	COG4948	Mandelate Racemase Muconate Lactonizing
C7R87_RS04510	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS04515	COG2186	Transcriptional regulator
C7R87_RS04540	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS04550	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS04555	COG1024	Enoyl-CoA hydratase
C7R87_RS04560	COG2814	Major facilitator Superfamily
C7R87_RS04575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7R87_RS04590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7R87_RS04635	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7R87_RS04650	COG0583	DNA-binding transcription factor activity
C7R87_RS04655	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
C7R87_RS04720	COG2746	aminoglycoside 3-N-acetyltransferase activity
C7R87_RS04725	COG1660	Displays ATPase and GTPase activities
C7R87_RS04745	COG2252	PERMEase
C7R87_RS04750	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C7R87_RS04755	COG3038	cytochrome b561
C7R87_RS04765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7R87_RS04775	COG0527	aspartate kinase activity
C7R87_RS04785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7R87_RS04795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7R87_RS04810	COG0667	Aldo Keto reductase
C7R87_RS04820	COG1765	OsmC-like protein
C7R87_RS04835	COG0542	response to heat
C7R87_RS04870	COG2885	chlorophyll binding
C7R87_RS04880	COG0625	glutathione transferase activity
C7R87_RS04885	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7R87_RS04905	COG3634	alkyl hydroperoxide reductase activity
C7R87_RS04915	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C7R87_RS04925	COG0450	alkyl hydroperoxide reductase
C7R87_RS04930	COG1643	Atp-dependent helicase
C7R87_RS04945	COG2814	Major facilitator Superfamily
C7R87_RS04950	COG3135	benzoate transporter
C7R87_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS04960	COG0543	2 iron, 2 sulfur cluster binding
C7R87_RS04960	COG0633	Ferredoxin
C7R87_RS04965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C7R87_RS04970	COG4638	Rieske (2fe-2S)
C7R87_RS04975	COG0583	DNA-binding transcription factor activity
C7R87_RS05030	COG1570	exodeoxyribonuclease VII activity
C7R87_RS05065	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS05070	COG1278	Cold shock
C7R87_RS05120	COG2814	Major facilitator Superfamily
C7R87_RS05160	COG0517	IMP dehydrogenase activity
C7R87_RS05160	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7R87_RS05165	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C7R87_RS05175	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C7R87_RS05180	COG1137	ATPase activity
C7R87_RS05215	COG4122	O-methyltransferase activity
C7R87_RS05225	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7R87_RS05240	COG1522	sequence-specific DNA binding
C7R87_RS05245	COG5006	permease, DMT superfamily
C7R87_RS05255	COG1560	Kdo2-lipid A biosynthetic process
C7R87_RS05265	COG2814	Major facilitator Superfamily
C7R87_RS05285	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7R87_RS05340	COG0583	DNA-binding transcription factor activity
C7R87_RS05345	COG1914	H( )-stimulated, divalent metal cation uptake system
C7R87_RS05365	COG4770	biotin carboxylase activity
C7R87_RS05370	COG0038	chloride channel
C7R87_RS05395	COG1309	transcriptional regulator
C7R87_RS05405	COG1063	alcohol dehydrogenase
C7R87_RS05420	COG0439	Biotin carboxylase
C7R87_RS05425	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7R87_RS05445	COG0864	Transcriptional regulator
C7R87_RS05455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7R87_RS05460	COG1116	anion transmembrane transporter activity
C7R87_RS05580	COG0590	tRNA wobble adenosine to inosine editing
C7R87_RS05585	COG2807	transmembrane transport
C7R87_RS05600	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C7R87_RS05610	COG0789	Transcriptional regulator
C7R87_RS05630	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7R87_RS05650	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7R87_RS05660	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7R87_RS05685	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS05690	COG0531	amino acid
C7R87_RS05695	COG1760	l-serine dehydratase
C7R87_RS05700	COG2030	dehydratase
C7R87_RS05700	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS05705	COG3396	Phenylacetate-CoA oxygenase
C7R87_RS05710	COG3460	Phenylacetate-CoA oxygenase
C7R87_RS05715	COG3396	Phenylacetate-CoA oxygenase
C7R87_RS05720	COG2151	metal-sulfur cluster biosynthetic enzyme
C7R87_RS05725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7R87_RS05730	COG1024	Enoyl-CoA hydratase
C7R87_RS05735	COG1024	Enoyl-CoA hydratase
C7R87_RS05740	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7R87_RS05745	COG0183	Belongs to the thiolase family
C7R87_RS05750	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
C7R87_RS05755	COG3327	negative regulation of DNA-templated transcription, initiation
C7R87_RS05765	COG2050	protein possibly involved in aromatic compounds catabolism
C7R87_RS05805	COG0753	catalase activity
C7R87_RS05810	COG3038	cytochrome b561
C7R87_RS05830	COG2267	carboxylic ester hydrolase activity
C7R87_RS05835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7R87_RS05840	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7R87_RS05845	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS05855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7R87_RS05865	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS05870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7R87_RS05875	COG0583	DNA-binding transcription factor activity
C7R87_RS05885	COG1414	Transcriptional regulator
C7R87_RS05890	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7R87_RS05900	COG1840	ABC-type Fe3 transport system, periplasmic component
C7R87_RS05905	COG3842	ATPase activity
C7R87_RS05920	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7R87_RS05925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7R87_RS05930	COG2814	Major facilitator Superfamily
C7R87_RS05935	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS05950	COG1024	Enoyl-CoA hydratase
C7R87_RS05960	COG2814	Major facilitator Superfamily
C7R87_RS05970	COG0183	Belongs to the thiolase family
C7R87_RS05975	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7R87_RS05980	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS05985	COG1024	Enoyl-CoA hydratase
C7R87_RS05990	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS05995	COG2814	Major facilitator Superfamily
C7R87_RS06000	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7R87_RS06005	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7R87_RS06015	COG2814	Major facilitator Superfamily
C7R87_RS06025	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS06040	COG0583	DNA-binding transcription factor activity
C7R87_RS06050	COG4770	biotin carboxylase activity
C7R87_RS06055	COG1024	Enoyl-CoA hydratase
C7R87_RS06060	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7R87_RS06065	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS06070	COG1309	transcriptional regulator
C7R87_RS06075	COG0318	PFAM AMP-dependent synthetase and ligase
C7R87_RS06095	COG0583	DNA-binding transcription factor activity
C7R87_RS06140	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS06160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7R87_RS06180	COG2205	protein histidine kinase activity
C7R87_RS06180	COG0784	Response regulator, receiver
C7R87_RS06200	COG0765	amino acid transport
C7R87_RS06205	COG0765	amino acid transport
C7R87_RS06210	COG1126	abc transporter atp-binding protein
C7R87_RS06215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7R87_RS06220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7R87_RS06235	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS06245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7R87_RS06250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7R87_RS06255	COG1045	serine acetyltransferase
C7R87_RS06270	COG0583	DNA-binding transcription factor activity
C7R87_RS06275	COG0625	glutathione transferase activity
C7R87_RS06280	COG0625	glutathione transferase activity
C7R87_RS06285	COG0583	DNA-binding transcription factor activity
C7R87_RS06295	COG1346	cytolysis
C7R87_RS06315	COG2814	Major facilitator Superfamily
C7R87_RS06325	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
C7R87_RS06330	COG3052	prosthetic group binding
C7R87_RS06350	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
C7R87_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7R87_RS06380	COG1294	oxidase, subunit
C7R87_RS06385	COG1271	oxidase subunit
C7R87_RS06410	COG0477	Major facilitator Superfamily
C7R87_RS06430	COG4521	taurine ABC transporter
C7R87_RS06435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
C7R87_RS06440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7R87_RS06445	COG2175	clavaminate synthase activity
C7R87_RS06455	COG1953	Uracil, thiamine, allantoin
C7R87_RS06465	COG0583	DNA-binding transcription factor activity
C7R87_RS06475	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
C7R87_RS06490	COG0640	Transcriptional regulator
C7R87_RS06495	COG0798	PFAM Bile acid sodium symporter
C7R87_RS06500	COG0583	DNA-binding transcription factor activity
C7R87_RS06515	COG3634	alkyl hydroperoxide reductase activity
C7R87_RS06555	COG0436	Aminotransferase
C7R87_RS06565	COG0386	Belongs to the glutathione peroxidase family
C7R87_RS06605	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7R87_RS06635	COG0012	GTP binding
C7R87_RS06640	COG2011	ABC-type metal ion transport system permease component
C7R87_RS06645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7R87_RS06655	COG1464	Belongs to the NlpA lipoprotein family
C7R87_RS06685	COG0765	amino acid transport
C7R87_RS06690	COG0765	amino acid transport
C7R87_RS06695	COG1126	abc transporter atp-binding protein
C7R87_RS06705	COG1522	sequence-specific DNA binding
C7R87_RS06720	COG1309	transcriptional regulator
C7R87_RS06745	COG0583	DNA-binding transcription factor activity
C7R87_RS06755	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
C7R87_RS06765	COG0697	spore germination
C7R87_RS06805	COG3121	Chaperone
C7R87_RS06810	COG3539	Fimbrial protein
C7R87_RS06835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7R87_RS06835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7R87_RS06880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7R87_RS06890	COG2353	YceI-like domain
C7R87_RS06900	COG3698	Phosphodiester glycosidase
C7R87_RS06915	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
C7R87_RS06920	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7R87_RS06920	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7R87_RS06920	COG0506	proline dehydrogenase activity
C7R87_RS06930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7R87_RS06935	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C7R87_RS06960	COG1132	(ABC) transporter
C7R87_RS06965	COG3122	Protein conserved in bacteria
C7R87_RS06970	COG3619	membrane
C7R87_RS06980	COG0640	Transcriptional regulator
C7R87_RS06990	COG2850	peptidyl-arginine hydroxylation
C7R87_RS06995	COG0424	maF-like protein
C7R87_RS07015	COG0191	fructose-bisphosphate aldolase activity
C7R87_RS07020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7R87_RS07035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7R87_RS07045	COG1192	Involved in chromosome partitioning
C7R87_RS07050	COG1475	DNA binding
C7R87_RS07055	COG0811	peptide transport
C7R87_RS07065	COG1132	(ABC) transporter
C7R87_RS07070	COG1663	tetraacyldisaccharide 4'-kinase activity
C7R87_RS07090	COG0084	hydrolase, TatD family'
C7R87_RS07155	COG0776	regulation of translation
C7R87_RS07185	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C7R87_RS07190	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7R87_RS07250	COG0339	signal peptide processing
C7R87_RS07295	COG0702	epimerase
C7R87_RS07300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7R87_RS07320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7R87_RS07350	COG0316	Belongs to the HesB IscA family
C7R87_RS07355	COG0822	iron-sulfur transferase activity
C7R87_RS07380	COG0776	regulation of translation
C7R87_RS07385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7R87_RS07390	COG2207	Transcriptional regulator
C7R87_RS07395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7R87_RS07400	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS07405	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS07420	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C7R87_RS07440	COG4264	IucA IucC family
C7R87_RS07445	COG4264	IucA IucC family
C7R87_RS07505	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
C7R87_RS07525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7R87_RS07530	COG0730	response to heat
C7R87_RS07555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7R87_RS07570	COG1131	(ABC) transporter
C7R87_RS07575	COG0842	Transport permease protein
C7R87_RS07580	COG0842	Transport permease protein
C7R87_RS07635	COG2226	methyltransferase
C7R87_RS07660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7R87_RS07695	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7R87_RS07705	COG0133	tryptophan synthase activity
C7R87_RS07720	COG3706	GGDEF domain
C7R87_RS07740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7R87_RS07745	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C7R87_RS07750	COG0022	dehydrogenase e1 component
C7R87_RS07755	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7R87_RS07760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7R87_RS07785	COG1063	alcohol dehydrogenase
C7R87_RS07790	COG3781	membrane
C7R87_RS07800	COG3453	Protein conserved in bacteria
C7R87_RS07800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7R87_RS07810	COG0730	response to heat
C7R87_RS07825	COG3708	Transcriptional regulator
C7R87_RS07825	COG2207	Transcriptional regulator
C7R87_RS07830	COG1733	regulation of RNA biosynthetic process
C7R87_RS07835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7R87_RS07845	COG2188	Transcriptional regulator
C7R87_RS07860	COG4521	taurine ABC transporter
C7R87_RS07865	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7R87_RS07885	COG0477	Major facilitator Superfamily
C7R87_RS07895	COG1027	Aspartate ammonia-lyase
C7R87_RS07910	COG0583	DNA-binding transcription factor activity
C7R87_RS07915	COG0583	DNA-binding transcription factor activity
C7R87_RS07920	COG0183	Belongs to the thiolase family
C7R87_RS07925	COG2031	fatty acid transporter
C7R87_RS07930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7R87_RS07940	COG0583	DNA-binding transcription factor activity
C7R87_RS07950	COG2610	gluconate transmembrane transporter activity
C7R87_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS07960	COG2207	Transcriptional regulator
C7R87_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS08000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7R87_RS08000	COG0543	2 iron, 2 sulfur cluster binding
C7R87_RS08005	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
C7R87_RS08010	COG4638	Rieske (2fe-2S)
C7R87_RS08020	COG0725	ABC transporter, periplasmic molybdate-binding protein
C7R87_RS08025	COG4149	molybdate abc transporter
C7R87_RS08030	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C7R87_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS08040	COG1535	isochorismatase
C7R87_RS08040	COG3433	isochorismatase activity
C7R87_RS08105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7R87_RS08120	COG0753	catalase activity
C7R87_RS08130	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
C7R87_RS08155	COG3539	Fimbrial protein
C7R87_RS08175	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7R87_RS08195	COG2072	flavoprotein involved in K transport
C7R87_RS08205	COG1538	Outer membrane efflux protein
C7R87_RS08210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7R87_RS08215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7R87_RS08220	COG0745	RESPONSE REGULATOR receiver
C7R87_RS08225	COG2205	protein histidine kinase activity
C7R87_RS08235	COG2207	Transcriptional regulator
C7R87_RS08250	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS08305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7R87_RS08425	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7R87_RS08445	COG1120	ATPase activity
C7R87_RS08450	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7R87_RS08460	COG1064	alcohol dehydrogenase
C7R87_RS08475	COG2207	Transcriptional regulator
C7R87_RS08480	COG2084	Dehydrogenase
C7R87_RS08490	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7R87_RS08495	COG0583	DNA-binding transcription factor activity
C7R87_RS08505	COG0129	dihydroxy-acid dehydratase activity
C7R87_RS08510	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS08540	COG0583	DNA-binding transcription factor activity
C7R87_RS08545	COG4948	Mandelate Racemase Muconate Lactonizing
C7R87_RS08550	COG4829	muconolactone delta-isomerase
C7R87_RS08560	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7R87_RS08565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7R87_RS08570	COG0183	Belongs to the thiolase family
C7R87_RS08575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7R87_RS08585	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS08595	COG3733	amine oxidase
C7R87_RS08605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7R87_RS08615	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS08625	COG4638	Rieske (2fe-2S)
C7R87_RS08645	COG0154	amidase activity
C7R87_RS08655	COG2814	Major facilitator Superfamily
C7R87_RS08680	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS08685	COG0583	DNA-binding transcription factor activity
C7R87_RS08690	COG1414	Transcriptional regulator
C7R87_RS08705	COG2391	methyltransferase activity
C7R87_RS08715	COG4993	Dehydrogenase
C7R87_RS08720	COG3659	wide pore channel activity
C7R87_RS08725	COG3420	alginic acid biosynthetic process
C7R87_RS08730	COG0710	3-dehydroquinate dehydratase activity
C7R87_RS08735	COG3485	protocatechuate 3,4-dioxygenase
C7R87_RS08740	COG3485	protocatechuate 3,4-dioxygenase
C7R87_RS08745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7R87_RS08750	COG2271	Major facilitator Superfamily
C7R87_RS08755	COG0596	Alpha beta hydrolase
C7R87_RS08760	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7R87_RS08765	COG0183	Belongs to the thiolase family
C7R87_RS08770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
C7R87_RS08775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
C7R87_RS08785	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7R87_RS08790	COG2323	membrane
C7R87_RS08835	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7R87_RS08835	COG1902	pentaerythritol trinitrate reductase activity
C7R87_RS08860	COG0542	response to heat
C7R87_RS08865	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7R87_RS08895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C7R87_RS08900	COG0569	domain protein
C7R87_RS08905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7R87_RS08920	COG4774	siderophore transport
C7R87_RS08925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7R87_RS08935	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7R87_RS08955	COG1294	oxidase, subunit
C7R87_RS08960	COG4890	Cyd operon protein YbgT
C7R87_RS08975	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C7R87_RS08985	COG0552	protein localization to endoplasmic reticulum
C7R87_RS09010	COG0517	IMP dehydrogenase activity
C7R87_RS09010	COG0516	GMP reductase activity
C7R87_RS09015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7R87_RS09020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7R87_RS09030	COG0583	DNA-binding transcription factor activity
C7R87_RS09035	COG0024	Methionine aminopeptidase
C7R87_RS09065	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7R87_RS09065	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7R87_RS09070	COG1105	Belongs to the carbohydrate kinase PfkB family
C7R87_RS09075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7R87_RS09075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7R87_RS09075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C7R87_RS09095	COG3300	MHYT domain
C7R87_RS09095	COG5001	Diguanylate cyclase
C7R87_RS09110	COG2135	peptidase activity
C7R87_RS09115	COG0659	secondary active sulfate transmembrane transporter activity
C7R87_RS09130	COG1113	amino acid transport
C7R87_RS09140	COG1522	sequence-specific DNA binding
C7R87_RS09165	COG1011	Hydrolase
C7R87_RS09170	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
C7R87_RS09180	COG2137	regulation of response to DNA damage stimulus
C7R87_RS09195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7R87_RS09230	COG0575	Belongs to the CDS family
C7R87_RS09235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7R87_RS09255	COG3852	Histidine kinase
C7R87_RS09260	COG2204	response regulator
C7R87_RS09320	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7R87_RS09325	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C7R87_RS09345	COG0697	spore germination
C7R87_RS09350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7R87_RS09360	COG0303	'Molybdopterin
C7R87_RS09365	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7R87_RS09365	COG0315	cyclic pyranopterin monophosphate synthase activity
C7R87_RS09380	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7R87_RS09385	COG0243	molybdopterin cofactor binding
C7R87_RS09395	COG0243	molybdopterin cofactor binding
C7R87_RS09400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7R87_RS09405	COG2146	nitrite reductase [NAD(P)H] activity
C7R87_RS09405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7R87_RS09415	COG0745	RESPONSE REGULATOR receiver
C7R87_RS09420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7R87_RS09420	COG1116	anion transmembrane transporter activity
C7R87_RS09440	COG0511	ligase activity, forming carbon-carbon bonds
C7R87_RS09455	COG2814	Major facilitator Superfamily
C7R87_RS09530	COG0592	DNA-directed DNA polymerase activity
C7R87_RS09570	COG2026	Addiction module toxin, RelE StbE family
C7R87_RS09875	COG0069	glutamate synthase activity
C7R87_RS09895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C7R87_RS09905	COG1454	alcohol dehydrogenase
C7R87_RS09910	COG0824	Thioesterase
C7R87_RS09920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7R87_RS09935	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7R87_RS09940	COG2030	dehydratase
C7R87_RS09950	COG0183	Belongs to the thiolase family
C7R87_RS09960	COG0583	DNA-binding transcription factor activity
C7R87_RS09965	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7R87_RS09975	COG1522	sequence-specific DNA binding
C7R87_RS09980	COG3135	benzoate transporter
C7R87_RS09990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
C7R87_RS10005	COG0589	response to stress
C7R87_RS10010	COG0488	(ABC) transporter
C7R87_RS10035	COG0668	transmembrane transport
C7R87_RS10045	COG1309	transcriptional regulator
C7R87_RS10065	COG1605	Chorismate mutase
C7R87_RS10075	COG4221	oxidoreductase activity
C7R87_RS10085	COG0308	aminopeptidase N
C7R87_RS10105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
C7R87_RS10115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7R87_RS10120	COG1454	alcohol dehydrogenase
C7R87_RS10140	COG0531	amino acid
C7R87_RS10145	COG4303	Ethanolamine ammonia lyase large subunit
C7R87_RS10150	COG4302	ethanolamine ammonia-lyase activity
C7R87_RS10155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7R87_RS10155	COG0519	Catalyzes the synthesis of GMP from XMP
C7R87_RS10160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7R87_RS10170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7R87_RS10185	COG0697	spore germination
C7R87_RS10190	COG1923	regulation of RNA biosynthetic process
C7R87_RS10200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7R87_RS10205	COG0802	atpase or kinase
C7R87_RS10225	COG1187	pseudouridine synthase activity
C7R87_RS10240	COG0583	DNA-binding transcription factor activity
C7R87_RS10255	COG2814	Major facilitator Superfamily
C7R87_RS10260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7R87_RS10295	COG0729	surface antigen
C7R87_RS10315	COG0174	glutamine synthetase
C7R87_RS10320	COG0745	RESPONSE REGULATOR receiver
C7R87_RS10325	COG2205	protein histidine kinase activity
C7R87_RS10335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
C7R87_RS10340	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
C7R87_RS10365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7R87_RS10370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7R87_RS10375	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS10390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7R87_RS10395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7R87_RS10415	COG0583	DNA-binding transcription factor activity
C7R87_RS10435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7R87_RS10445	COG3658	cytochrome
C7R87_RS10450	COG1215	transferase activity, transferring glycosyl groups
C7R87_RS10455	COG1649	PFAM Uncharacterised BCR, COG1649
C7R87_RS10455	COG0726	polysaccharide deacetylase
C7R87_RS10490	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7R87_RS10495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7R87_RS10505	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7R87_RS10530	COG0305	Participates in initiation and elongation during chromosome replication
C7R87_RS10535	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7R87_RS10545	COG1305	Transglutaminase-like
C7R87_RS10555	COG2308	Evidence 4 Homologs of previously reported genes of
C7R87_RS10585	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C7R87_RS10590	COG0138	bifunctional purine biosynthesis protein purh
C7R87_RS10595	COG0151	Belongs to the GarS family
C7R87_RS10600	COG1464	Belongs to the NlpA lipoprotein family
C7R87_RS10605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7R87_RS10610	COG2011	ABC-type metal ion transport system permease component
C7R87_RS10615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7R87_RS10630	COG1301	dicarboxylic acid transport
C7R87_RS10660	COG1794	racemase activity, acting on amino acids and derivatives
C7R87_RS10680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7R87_RS10680	COG3008	intermembrane lipid transfer
C7R87_RS10685	COG2995	paraquat-inducible protein a
C7R87_RS10700	COG2985	domain, Protein
C7R87_RS10730	COG0477	Major facilitator Superfamily
C7R87_RS10785	COG2186	Transcriptional regulator
C7R87_RS10795	COG0786	glutamate:sodium symporter activity
C7R87_RS10800	COG3243	poly(R)-hydroxyalkanoic acid synthase
C7R87_RS10825	COG3111	PFAM Bacterial OB fold (BOF) protein
C7R87_RS10925	COG1610	YqeY-like protein
C7R87_RS10930	COG4783	chaperone-mediated protein folding
C7R87_RS10955	COG1286	toxin biosynthetic process
C7R87_RS10985	COG0778	Nitroreductase
C7R87_RS10995	COG0513	Belongs to the DEAD box helicase family
C7R87_RS11015	COG2363	Small membrane protein
C7R87_RS11045	COG1234	tRNA 3'-trailer cleavage
C7R87_RS11050	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7R87_RS11060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7R87_RS11070	COG2819	hydrolase of the alpha beta superfamily
C7R87_RS11075	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS11080	COG1301	dicarboxylic acid transport
C7R87_RS11090	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7R87_RS11095	COG3139	Protein of unknown function (DUF1315)
C7R87_RS11100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7R87_RS11105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7R87_RS11115	COG0494	nUDIX hydrolase
C7R87_RS11125	COG0642	Histidine kinase
C7R87_RS11140	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7R87_RS11150	COG1720	tRNA m6t6A37 methyltransferase activity
C7R87_RS11165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7R87_RS11170	COG0826	peptidase U32
C7R87_RS11175	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7R87_RS11185	COG4598	ABC transporter
C7R87_RS11190	COG4160	amino acid transport
C7R87_RS11195	COG4215	(ABC) transporter
C7R87_RS11210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7R87_RS11255	COG1131	(ABC) transporter
C7R87_RS11260	COG0842	Transport permease protein
C7R87_RS11275	COG0772	Belongs to the SEDS family
C7R87_RS11280	COG2951	lytic endotransglycosylase activity
C7R87_RS11305	COG2207	Transcriptional regulator
C7R87_RS11320	COG0052	Belongs to the universal ribosomal protein uS2 family
C7R87_RS11325	COG0024	Methionine aminopeptidase
C7R87_RS11335	COG2223	nitrite transmembrane transporter activity
C7R87_RS11345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7R87_RS11350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7R87_RS11355	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS11370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C7R87_RS11375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
C7R87_RS11380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7R87_RS11400	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7R87_RS11405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C7R87_RS11410	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7R87_RS11445	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7R87_RS11455	COG0174	glutamine synthetase
C7R87_RS11840	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7R87_RS11865	COG3384	dioxygenase
C7R87_RS11875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7R87_RS11880	COG2878	Part of a membrane complex involved in electron transport
C7R87_RS11885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7R87_RS11910	COG0768	penicillin binding
C7R87_RS11915	COG0742	ribosomal rna small subunit methyltransferase
C7R87_RS11930	COG0830	nickel cation binding
C7R87_RS11940	COG0804	urea catabolic process
C7R87_RS12035	COG1773	rubredoxin
C7R87_RS12040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7R87_RS12050	COG0583	DNA-binding transcription factor activity
C7R87_RS12075	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C7R87_RS12080	COG4181	ATPase activity
C7R87_RS12125	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C7R87_RS12145	COG0306	phosphate transporter
C7R87_RS12155	COG3958	Transketolase
C7R87_RS12160	COG3959	Transketolase, thiamine diphosphate binding domain
C7R87_RS12165	COG2271	Major facilitator Superfamily
C7R87_RS12170	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS12175	COG0583	DNA-binding transcription factor activity
C7R87_RS12195	COG2223	nitrite transmembrane transporter activity
C7R87_RS12200	COG2207	Transcriptional regulator
C7R87_RS12205	COG2066	Belongs to the glutaminase family
C7R87_RS12210	COG0242	peptide deformylase activity
C7R87_RS12215	COG0477	Major facilitator Superfamily
C7R87_RS12225	COG0028	Belongs to the TPP enzyme family
C7R87_RS12240	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS12245	COG2267	carboxylic ester hydrolase activity
C7R87_RS12255	COG2271	Major facilitator Superfamily
C7R87_RS12260	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7R87_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS12290	COG1414	Transcriptional regulator
C7R87_RS12305	COG1024	Enoyl-CoA hydratase
C7R87_RS12315	COG1215	transferase activity, transferring glycosyl groups
C7R87_RS12320	COG1649	PFAM Uncharacterised BCR, COG1649
C7R87_RS12320	COG0726	polysaccharide deacetylase
C7R87_RS12330	COG4681	YaeQ
C7R87_RS12340	COG0523	cobalamin synthesis protein
C7R87_RS12350	COG1607	acyl-coa hydrolase
C7R87_RS12360	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7R87_RS12365	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7R87_RS12370	COG1309	transcriptional regulator
C7R87_RS12395	COG2040	homocysteine
C7R87_RS12400	COG0531	amino acid
C7R87_RS12455	COG1595	DNA-templated transcription, initiation
C7R87_RS12465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7R87_RS12470	COG0477	Major facilitator Superfamily
C7R87_RS12535	COG1196	nuclear chromosome segregation
C7R87_RS12535	COG0741	lytic transglycosylase activity
C7R87_RS12535	COG0739	heme binding
C7R87_RS12550	COG1598	PFAM Uncharacterised protein family UPF0150
C7R87_RS12670	COG5410	chromosome segregation
C7R87_RS12820	COG0405	Gamma-glutamyltransferase
C7R87_RS12825	COG2814	Major facilitator Superfamily
C7R87_RS12835	COG2050	protein possibly involved in aromatic compounds catabolism
C7R87_RS12850	COG1090	epimerase
C7R87_RS12870	COG0420	3'-5' exonuclease activity
C7R87_RS12895	COG0735	belongs to the Fur family
C7R87_RS12900	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7R87_RS12925	COG0121	glutamine amidotransferase
C7R87_RS12940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7R87_RS12950	COG0210	DNA helicase
C7R87_RS12955	COG2885	chlorophyll binding
C7R87_RS12960	COG0204	Acyl-transferase
C7R87_RS12975	COG2894	cell division
C7R87_RS12995	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS13000	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7R87_RS13000	COG1674	ftsk spoiiie
C7R87_RS13005	COG0492	ferredoxin-NADP+ reductase activity
C7R87_RS13015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7R87_RS13025	COG0456	acetyltransferase
C7R87_RS13070	COG1981	membrane
C7R87_RS13085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7R87_RS13085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7R87_RS13105	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS13115	COG0657	acetylesterase activity
C7R87_RS13125	COG0473	3-isopropylmalate dehydrogenase activity
C7R87_RS13130	COG0583	DNA-binding transcription factor activity
C7R87_RS13150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7R87_RS13175	COG0564	pseudouridine synthase activity
C7R87_RS13185	COG0358	DNA primase activity
C7R87_RS13200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C7R87_RS13230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7R87_RS13260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7R87_RS13270	COG0352	thiamine-phosphate diphosphorylase activity
C7R87_RS13270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7R87_RS13270	COG0351	phosphomethylpyrimidine kinase
C7R87_RS13275	COG1652	LysM domain
C7R87_RS13300	COG1399	metal-binding, possibly nucleic acid-binding protein
C7R87_RS13305	COG3101	peptidyl-lysine hydroxylation
C7R87_RS13310	COG0009	L-threonylcarbamoyladenylate synthase
C7R87_RS13315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
C7R87_RS13320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7R87_RS13335	COG4106	trans-aconitate 2-methyltransferase activity
C7R87_RS13350	COG0596	Alpha beta hydrolase
C7R87_RS13350	COG2226	methyltransferase
C7R87_RS13350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7R87_RS13360	COG2826	transposase and inactivated derivatives, IS30 family
C7R87_RS13370	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
C7R87_RS13375	COG2223	nitrite transmembrane transporter activity
C7R87_RS13395	COG1196	nuclear chromosome segregation
C7R87_RS13405	COG0730	response to heat
C7R87_RS13420	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7R87_RS13430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7R87_RS13490	COG0489	protein tyrosine kinase activity
C7R87_RS13500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7R87_RS13500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7R87_RS13530	COG2515	1-aminocyclopropane-1-carboxylate deaminase
C7R87_RS13535	COG2081	HI0933 family
C7R87_RS13545	COG0668	transmembrane transport
C7R87_RS13565	COG0583	DNA-binding transcription factor activity
C7R87_RS13585	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7R87_RS13590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7R87_RS13620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
C7R87_RS13660	COG0745	RESPONSE REGULATOR receiver
C7R87_RS13680	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7R87_RS13690	COG2205	protein histidine kinase activity
C7R87_RS13700	COG2826	transposase and inactivated derivatives, IS30 family
C7R87_RS13710	COG2826	transposase and inactivated derivatives, IS30 family
C7R87_RS13780	COG4993	Dehydrogenase
C7R87_RS13800	COG0384	phenazine biosynthesis protein PhzF
C7R87_RS13830	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7R87_RS13845	COG0583	DNA-binding transcription factor activity
C7R87_RS13875	COG0583	DNA-binding transcription factor activity
C7R87_RS13895	COG0583	DNA-binding transcription factor activity
C7R87_RS13900	COG1053	succinate dehydrogenase
C7R87_RS13910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C7R87_RS13915	COG2814	Major facilitator Superfamily
C7R87_RS13920	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS13925	COG0583	DNA-binding transcription factor activity
C7R87_RS13930	COG1063	alcohol dehydrogenase
C7R87_RS13960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7R87_RS13965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
C7R87_RS13970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7R87_RS13985	COG3667	copper resistance
C7R87_RS13990	COG2132	Multicopper oxidase
C7R87_RS14000	COG0561	phosphatase activity
C7R87_RS14005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7R87_RS14030	COG1214	PFAM Peptidase M22, glycoprotease
C7R87_RS14075	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7R87_RS14085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7R87_RS14090	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7R87_RS14095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7R87_RS14155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7R87_RS14165	COG1846	Transcriptional regulator
C7R87_RS14170	COG1764	response to oxidative stress
C7R87_RS14210	COG0037	tRNA processing
C7R87_RS14220	COG0248	Ppx GppA phosphatase
C7R87_RS14250	COG0072	phenylalanine-tRNA ligase activity
C7R87_RS14290	COG1238	metal cluster binding
C7R87_RS14295	COG0625	glutathione transferase activity
C7R87_RS14315	COG0318	PFAM AMP-dependent synthetase and ligase
C7R87_RS14320	COG3028	Belongs to the UPF0307 family
C7R87_RS14325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7R87_RS14345	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C7R87_RS14350	COG0617	tRNA 3'-terminal CCA addition
C7R87_RS14355	COG1555	photosystem II stabilization
C7R87_RS14360	COG3956	TIGRFAM MazG family protein
C7R87_RS14370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7R87_RS14390	COG5002	protein histidine kinase activity
C7R87_RS14390	COG2205	protein histidine kinase activity
C7R87_RS14390	COG0784	Response regulator, receiver
C7R87_RS14395	COG1024	Enoyl-CoA hydratase
C7R87_RS14400	COG2084	Dehydrogenase
C7R87_RS14405	COG3622	Belongs to the hyi family
C7R87_RS14435	COG0697	spore germination
C7R87_RS14445	COG2814	Major facilitator Superfamily
C7R87_RS14450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7R87_RS14460	COG0583	DNA-binding transcription factor activity
C7R87_RS14470	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7R87_RS14485	COG0084	hydrolase, TatD family'
C7R87_RS14500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7R87_RS14535	COG0440	acetolactate synthase activity
C7R87_RS14540	COG0028	Belongs to the TPP enzyme family
C7R87_RS14580	COG1136	(ABC) transporter
C7R87_RS14580	COG0577	efflux transmembrane transporter activity
C7R87_RS14585	COG1538	Outer membrane efflux protein
C7R87_RS14600	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C7R87_RS14605	COG1162	GTPase activity
C7R87_RS14615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7R87_RS14635	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7R87_RS14640	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS14680	COG2986	histidine ammonia-lyase
C7R87_RS14695	COG0318	PFAM AMP-dependent synthetase and ligase
C7R87_RS14705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7R87_RS14750	COG1426	Protein conserved in bacteria
C7R87_RS14785	COG0793	Belongs to the peptidase S41A family
C7R87_RS14800	COG2267	carboxylic ester hydrolase activity
C7R87_RS14810	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS14815	COG3265	gluconokinase activity
C7R87_RS14825	COG0800	Aldolase
C7R87_RS14835	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7R87_RS14840	COG0280	phosphate acetyltransferase
C7R87_RS14840	COG0857	belongs to the CobB CobQ family
C7R87_RS14845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
C7R87_RS14845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
C7R87_RS14865	COG0740	serine-type endopeptidase activity
C7R87_RS14875	COG4774	siderophore transport
C7R87_RS14885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7R87_RS14895	COG2813	Specifically methylates the guanine in position
C7R87_RS14895	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C7R87_RS14995	COG0788	formyltetrahydrofolate deformylase activity
C7R87_RS15020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7R87_RS15020	COG4651	solute:proton antiporter activity
C7R87_RS15040	COG0724	RNA recognition motif
C7R87_RS15045	COG0210	DNA helicase
C7R87_RS15070	COG1733	regulation of RNA biosynthetic process
C7R87_RS15080	COG2900	Belongs to the SlyX family
C7R87_RS15085	COG0488	(ABC) transporter
C7R87_RS15090	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS15095	COG1560	Kdo2-lipid A biosynthetic process
C7R87_RS15105	COG1301	dicarboxylic acid transport
C7R87_RS15165	COG0473	3-isopropylmalate dehydrogenase activity
C7R87_RS15230	COG0583	DNA-binding transcription factor activity
C7R87_RS15240	COG0625	glutathione transferase activity
C7R87_RS15245	COG2378	regulation of single-species biofilm formation
C7R87_RS15250	COG0546	phosphoglycolate phosphatase activity
C7R87_RS15265	COG1530	ribonuclease E activity
C7R87_RS15270	COG0318	PFAM AMP-dependent synthetase and ligase
C7R87_RS15285	COG0583	DNA-binding transcription factor activity
C7R87_RS15290	COG4221	oxidoreductase activity
C7R87_RS15295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7R87_RS15305	COG0534	Mate efflux family protein
C7R87_RS15320	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7R87_RS15360	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C7R87_RS15365	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7R87_RS15380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7R87_RS15390	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C7R87_RS15390	COG0644	oxidoreductase
C7R87_RS15395	COG0425	Belongs to the sulfur carrier protein TusA family
C7R87_RS15400	COG4535	Mg2 and Co2 transporter CorC
C7R87_RS15410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7R87_RS15430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7R87_RS15435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7R87_RS15435	COG0475	glutathione-regulated potassium exporter activity
C7R87_RS15440	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7R87_RS15450	COG0484	heat shock protein binding
C7R87_RS15455	COG0789	Transcriptional regulator
C7R87_RS15460	COG0598	Magnesium transport protein CorA
C7R87_RS15475	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C7R87_RS15480	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7R87_RS15485	COG1074	ATP-dependent DNA helicase activity
C7R87_RS15490	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C7R87_RS15510	COG2226	methyltransferase
C7R87_RS15525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7R87_RS15530	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7R87_RS15545	COG2111	Na H antiporter
C7R87_RS15545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
C7R87_RS15550	COG1006	Multisubunit Na H antiporter MnhC subunit
C7R87_RS15555	COG0651	ATP synthesis coupled electron transport
C7R87_RS15560	COG1863	multisubunit Na H antiporter MnhE subunit
C7R87_RS15565	COG2212	antiporter activity
C7R87_RS15570	COG1320	monovalent cation:proton antiporter activity
C7R87_RS15585	COG0195	Participates in both transcription termination and antitermination
C7R87_RS15635	COG0237	dephospho-CoA kinase activity
C7R87_RS15645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7R87_RS15660	COG0497	DNA recombination
C7R87_RS15670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7R87_RS15700	COG2169	Transcriptional regulator
C7R87_RS15700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C7R87_RS15705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7R87_RS15755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7R87_RS15815	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C7R87_RS15830	COG0326	Molecular chaperone. Has ATPase activity
C7R87_RS15845	COG2056	Na+-H+ antiporter family
C7R87_RS15850	COG0596	Alpha beta hydrolase
C7R87_RS15945	COG0546	phosphoglycolate phosphatase activity
C7R87_RS15950	COG1716	ATPase activity
C7R87_RS15995	COG0181	hydroxymethylbilane synthase activity
C7R87_RS16005	COG3275	phosphorelay sensor kinase activity
C7R87_RS16025	COG1538	Outer membrane efflux protein
C7R87_RS16030	COG0697	spore germination
C7R87_RS16055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
C7R87_RS16060	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7R87_RS16065	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7R87_RS16070	COG0772	Belongs to the SEDS family
C7R87_RS16095	COG4974	Belongs to the 'phage' integrase family
C7R87_RS16100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7R87_RS16110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7R87_RS16120	COG2197	response regulator
C7R87_RS16135	COG0793	Belongs to the peptidase S41A family
C7R87_RS16140	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7R87_RS16145	COG0795	lipopolysaccharide-transporting ATPase activity
C7R87_RS16185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7R87_RS16185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7R87_RS16195	COG0004	ammonium transporteR
C7R87_RS16200	COG0347	Belongs to the P(II) protein family
C7R87_RS16210	COG0606	chelatase, subunit chli
C7R87_RS16280	COG0659	secondary active sulfate transmembrane transporter activity
C7R87_RS16285	COG0589	response to stress
C7R87_RS16315	COG0606	chelatase, subunit chli
C7R87_RS16320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7R87_RS16330	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7R87_RS16345	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7R87_RS16360	COG0318	PFAM AMP-dependent synthetase and ligase
C7R87_RS16370	COG0477	Major facilitator Superfamily
C7R87_RS16375	COG2860	membrane
C7R87_RS16385	COG1253	flavin adenine dinucleotide binding
C7R87_RS16395	COG2814	Major facilitator Superfamily
C7R87_RS16405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7R87_RS16440	COG0655	NAD(P)H dehydrogenase (quinone) activity
C7R87_RS16450	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7R87_RS16485	COG1309	transcriptional regulator
C7R87_RS16520	COG0758	DNA mediated transformation
C7R87_RS16530	COG0697	spore germination
C7R87_RS16535	COG1309	transcriptional regulator
C7R87_RS16550	COG0386	Belongs to the glutathione peroxidase family
C7R87_RS16615	COG1121	(ABC) transporter
C7R87_RS16620	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7R87_RS16625	COG1280	lysine exporter protein (LysE YggA)
C7R87_RS16630	COG2837	iron assimilation
C7R87_RS16640	COG0281	malic enzyme
C7R87_RS16685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7R87_RS16685	COG0519	Catalyzes the synthesis of GMP from XMP
C7R87_RS16690	COG4399	Belongs to the UPF0754 family
C7R87_RS16695	COG2259	Doxx family
C7R87_RS16700	COG0586	Pfam SNARE associated Golgi protein
C7R87_RS16715	COG1192	Involved in chromosome partitioning
C7R87_RS16725	COG0271	Belongs to the BolA IbaG family
C7R87_RS16745	COG2267	carboxylic ester hydrolase activity
C7R87_RS16765	COG3321	synthase
C7R87_RS16765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7R87_RS16765	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7R87_RS16765	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
C7R87_RS16770	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS16785	COG2197	response regulator
C7R87_RS16795	COG3916	Acyl-homoserine-lactone synthase
C7R87_RS16800	COG0477	Major facilitator Superfamily
C7R87_RS16805	COG1024	Enoyl-CoA hydratase
C7R87_RS16810	COG1024	Enoyl-CoA hydratase
C7R87_RS16815	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS16820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7R87_RS16840	COG1113	amino acid transport
C7R87_RS16845	COG1113	amino acid transport
C7R87_RS16850	COG0251	oxidation-reduction process
C7R87_RS16890	COG0564	pseudouridine synthase activity
C7R87_RS16920	COG1051	belongs to the nudix hydrolase family
C7R87_RS16940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
C7R87_RS16955	COG1802	Transcriptional regulator
C7R87_RS16965	COG1448	Aminotransferase
C7R87_RS16970	COG0277	FAD linked oxidase domain protein
C7R87_RS16980	COG2186	Transcriptional regulator
C7R87_RS16990	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7R87_RS16995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7R87_RS17010	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7R87_RS17015	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C7R87_RS17020	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7R87_RS17075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
C7R87_RS17080	COG1596	polysaccharide export
C7R87_RS17105	COG0728	peptidoglycan biosynthetic process
C7R87_RS17110	COG3023	N-Acetylmuramoyl-L-alanine amidase
C7R87_RS17170	COG0546	phosphoglycolate phosphatase activity
C7R87_RS17175	COG1028	Short-chain dehydrogenase reductase Sdr
C7R87_RS17195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7R87_RS17200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7R87_RS17205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7R87_RS17210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7R87_RS17215	COG1116	anion transmembrane transporter activity
C7R87_RS17220	COG1309	transcriptional regulator
C7R87_RS17225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7R87_RS17235	COG0196	riboflavin kinase activity
C7R87_RS17240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C7R87_RS17250	COG1047	Peptidyl-prolyl cis-trans
C7R87_RS17290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7R87_RS17295	COG0657	acetylesterase activity
C7R87_RS17345	COG2951	lytic endotransglycosylase activity
C7R87_RS17350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7R87_RS17370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7R87_RS17380	COG0671	phosphoesterase, PA-phosphatase related
C7R87_RS17385	COG0861	Integral membrane protein TerC family
C7R87_RS17400	COG0754	glutathionylspermidine amidase activity
C7R87_RS17410	COG0402	S-adenosylhomocysteine deaminase activity
C7R87_RS17425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7R87_RS17430	COG1230	cation diffusion facilitator family transporter
C7R87_RS17445	COG0706	membrane insertase activity
C7R87_RS17470	COG0592	DNA-directed DNA polymerase activity
C7R87_RS17480	COG0187	DNA topoisomerase II activity
C7R87_RS17490	COG0586	Pfam SNARE associated Golgi protein
C7R87_RS17495	COG0488	(ABC) transporter
C7R87_RS17520	COG0596	Alpha beta hydrolase
C7R87_RS17525	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C7R87_RS17530	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7R87_RS17575	COG0733	neurotransmitter:sodium symporter activity
C7R87_RS17615	COG2233	PERMEase
C7R87_RS17630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7R87_RS17665	COG2814	Major facilitator Superfamily
C7R87_RS17670	COG0656	L-ascorbic acid biosynthetic process
C7R87_RS17675	COG0583	DNA-binding transcription factor activity
C7R87_RS17690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7R87_RS17695	COG1064	alcohol dehydrogenase
C7R87_RS17700	COG2818	Glycosylase
C7R87_RS17715	COG1194	a g-specific adenine glycosylase
C7R87_RS17735	COG2983	Belongs to the UPF0260 family
C7R87_RS17740	COG2133	pyrroloquinoline quinone binding
C7R87_RS17745	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7R87_RS17750	COG2116	formate transmembrane transporter activity
C7R87_RS17775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7R87_RS17780	COG1335	isochorismatase
C7R87_RS17785	COG0385	Bile acid
C7R87_RS17790	COG0534	Mate efflux family protein
C7R87_RS17795	COG1683	Conserved Protein
C7R87_RS17815	COG0625	glutathione transferase activity
C7R87_RS17825	COG1113	amino acid transport
C7R87_RS17835	COG0523	cobalamin synthesis protein
C7R87_RS17845	COG2188	Transcriptional regulator
C7R87_RS17875	COG0010	Belongs to the arginase family
C7R87_RS17885	COG0546	phosphoglycolate phosphatase activity
C7R87_RS17890	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7R87_RS17895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C7R87_RS17905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7R87_RS17910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7R87_RS17960	COG0753	catalase activity
C7R87_RS18020	COG0534	Mate efflux family protein
C7R87_RS18025	COG0436	Aminotransferase
C7R87_RS18030	COG2733	membrane
C7R87_RS18045	COG2918	glutathione biosynthetic process
C7R87_RS18060	COG3179	chitinase
C7R87_RS18085	COG3150	esterase
C7R87_RS18095	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
C7R87_RS18105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7R87_RS18115	COG2233	PERMEase
C7R87_RS18170	COG1393	Belongs to the ArsC family
C7R87_RS18175	COG0708	Exodeoxyribonuclease III
C7R87_RS18215	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7R87_RS18245	COG0189	ligase activity
C7R87_RS18265	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7R87_RS18275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7R87_RS18290	COG4942	peptidase
C7R87_RS18300	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7R87_RS18310	COG2119	membrane
C7R87_RS18315	COG4774	siderophore transport
C7R87_RS18320	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
C7R87_RS18320	COG0426	domain, Protein
C7R87_RS18345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7R87_RS18365	COG1902	pentaerythritol trinitrate reductase activity
C7R87_RS18370	COG1519	Transferase
C7R87_RS18375	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7R87_RS18380	COG0668	transmembrane transport
C7R87_RS18390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7R87_RS18395	COG1335	isochorismatase
C7R87_RS18400	COG1522	sequence-specific DNA binding
C7R87_RS18425	COG2205	protein histidine kinase activity
C7R87_RS18425	COG2198	Histidine kinase
C7R87_RS18425	COG0784	Response regulator, receiver
C7R87_RS18430	COG3162	membrane
C7R87_RS18435	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7R87_RS18445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C7R87_RS18460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7R87_RS18465	COG1309	transcriptional regulator
C7R87_RS18485	COG0351	phosphomethylpyrimidine kinase
C7R87_RS18485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
C7R87_RS18485	COG0352	thiamine-phosphate diphosphorylase activity
C7R87_RS18495	COG2814	Major facilitator Superfamily
C7R87_RS18510	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
C7R87_RS18520	COG1113	amino acid transport
C7R87_RS18530	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7R87_RS18535	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS18545	COG1335	isochorismatase
C7R87_RS18575	COG2814	Major facilitator Superfamily
C7R87_RS18580	COG0583	DNA-binding transcription factor activity
C7R87_RS18605	COG0667	Aldo Keto reductase
C7R87_RS18635	COG1733	regulation of RNA biosynthetic process
C7R87_RS18650	COG1733	regulation of RNA biosynthetic process
C7R87_RS18660	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7R87_RS18675	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C7R87_RS18680	COG2207	Transcriptional regulator
C7R87_RS18735	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7R87_RS18775	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7R87_RS18805	COG0427	acetyl-CoA hydrolase
C7R87_RS18830	COG0659	secondary active sulfate transmembrane transporter activity
C7R87_RS18835	COG4221	oxidoreductase activity
C7R87_RS18840	COG2873	o-acetylhomoserine
C7R87_RS18845	COG0488	(ABC) transporter
C7R87_RS18905	COG0833	amino acid
C7R87_RS18950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7R87_RS18955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7R87_RS18970	COG2226	methyltransferase
C7R87_RS19020	COG0069	glutamate synthase activity
C7R87_RS19020	COG0070	glutamate synthase
C7R87_RS19020	COG0067	glutamate synthase
C7R87_RS19025	COG0493	'glutamate synthase
C7R87_RS19035	COG1704	LemA family
C7R87_RS19040	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7R87_RS19060	COG3307	-O-antigen
C7R87_RS19085	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7R87_RS19100	COG0194	GDP metabolic process
C7R87_RS19150	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7R87_RS19170	COG5380	lipid catabolic process
C7R87_RS19175	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7R87_RS19200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7R87_RS19205	COG0277	FAD linked oxidase domain protein
C7R87_RS19215	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C7R87_RS19220	COG2249	NAD(P)H dehydrogenase (quinone) activity
C7R87_RS19235	COG1289	transmembrane transporter activity
C7R87_RS19245	COG0628	permease
C7R87_RS19250	COG1192	Involved in chromosome partitioning
C7R87_RS19280	COG0833	amino acid
C7R87_RS19285	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7R87_RS19290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7R87_RS19300	COG1012	belongs to the aldehyde dehydrogenase family
C7R87_RS19340	COG0583	DNA-binding transcription factor activity
C7R87_RS19385	COG0517	IMP dehydrogenase activity
C7R87_RS19390	COG1983	PspC domain protein
C7R87_RS19400	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS19415	COG0408	coproporphyrinogen oxidase activity
C7R87_RS19435	COG0513	Belongs to the DEAD box helicase family
C7R87_RS19445	COG1127	ABC transporter
C7R87_RS19450	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7R87_RS19460	COG2854	intermembrane phospholipid transfer
C7R87_RS19470	COG0598	Magnesium transport protein CorA
C7R87_RS19480	COG0494	nUDIX hydrolase
C7R87_RS19485	COG1040	competence protein
C7R87_RS19490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7R87_RS19510	COG1946	Acyl-CoA thioesterase
C7R87_RS19515	COG1301	dicarboxylic acid transport
C7R87_RS19530	COG1959	2 iron, 2 sulfur cluster binding
C7R87_RS19535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7R87_RS19535	COG1017	nitric oxide dioxygenase activity
C7R87_RS19540	COG0433	COG0433 Predicted ATPase
C7R87_RS19545	COG0626	cystathionine gamma-synthase activity
C7R87_RS19700	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS19705	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C7R87_RS19735	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C7R87_RS19740	COG0339	signal peptide processing
C7R87_RS19745	COG0557	exoribonuclease II activity
C7R87_RS19790	COG0179	Fumarylacetoacetate (FAA) hydrolase
C7R87_RS19795	COG2169	Transcriptional regulator
C7R87_RS19800	COG0697	spore germination
C7R87_RS19805	COG1295	ribonuclease BN
C7R87_RS19840	COG1702	phosphate starvation-inducible protein PhoH
C7R87_RS19850	COG1196	nuclear chromosome segregation
C7R87_RS19850	COG0741	lytic transglycosylase activity
C7R87_RS19850	COG0739	heme binding
C7R87_RS19880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C7R87_RS19885	COG1183	phosphatidylcholine synthase activity
C7R87_RS19930	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS19935	COG1309	transcriptional regulator
C7R87_RS19950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7R87_RS19955	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS19975	COG2969	positive regulation of protein catabolic process
C7R87_RS19985	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7R87_RS20000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7R87_RS20005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7R87_RS20035	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7R87_RS20040	COG1408	metallophosphoesterase
C7R87_RS20120	COG1607	acyl-coa hydrolase
C7R87_RS20150	COG2350	Protein conserved in bacteria
C7R87_RS20160	COG0613	PHP domain protein
C7R87_RS20165	COG3781	membrane
C7R87_RS20175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7R87_RS20180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7R87_RS20190	COG1862	Preprotein translocase
C7R87_RS20235	COG2205	protein histidine kinase activity
C7R87_RS20240	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C7R87_RS20260	COG0726	polysaccharide deacetylase
C7R87_RS20265	COG0463	Glycosyl transferase, family 2
C7R87_RS20270	COG0438	transferase activity, transferring glycosyl groups
C7R87_RS20355	COG0625	glutathione transferase activity
C7R87_RS20360	COG0583	DNA-binding transcription factor activity
C7R87_RS20365	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS20370	COG1960	acyl-CoA dehydrogenase activity
C7R87_RS20380	COG2205	protein histidine kinase activity
C7R87_RS20385	COG0745	RESPONSE REGULATOR receiver
C7R87_RS20390	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7R87_RS20410	COG2096	Adenosyltransferase
C7R87_RS20460	COG0285	dihydrofolate synthase activity
C7R87_RS20480	COG0450	alkyl hydroperoxide reductase
C7R87_RS20495	COG0477	Major facilitator Superfamily
C7R87_RS20500	COG1272	protein, Hemolysin III
C7R87_RS20530	COG0183	Belongs to the thiolase family
C7R87_RS20535	COG2207	Transcriptional regulator
C7R87_RS20555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7R87_RS20575	COG0183	Belongs to the thiolase family
C7R87_RS20585	COG2885	chlorophyll binding
C7R87_RS20585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C7R87_RS20595	COG1690	Belongs to the RtcB family
C7R87_RS20600	COG0833	amino acid
C7R87_RS20610	COG2233	PERMEase
C7R87_RS20615	COG1217	gtp-binding protein TYPA
C7R87_RS20640	COG2094	Belongs to the DNA glycosylase MPG family
C7R87_RS20645	COG4772	TonB-dependent receptor
C7R87_RS20650	COG1902	pentaerythritol trinitrate reductase activity
C7R87_RS20665	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7R87_RS20670	COG0354	folic acid binding
C7R87_RS20680	COG3189	MarR family transcriptional regulator
C7R87_RS20685	COG2824	Alkylphosphonate utilization operon protein PhnA
C7R87_RS20690	COG3422	double-strand break repair