locus-tag	class	description
CSB70_RS00070	COG0596	Alpha beta hydrolase
CSB70_RS00075	COG2056	Na+-H+ antiporter family
CSB70_RS00090	COG0326	Molecular chaperone. Has ATPase activity
CSB70_RS00105	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CSB70_RS00165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CSB70_RS00170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB70_RS00170	COG2169	Transcriptional regulator
CSB70_RS00200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CSB70_RS00210	COG0497	DNA recombination
CSB70_RS00225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB70_RS00235	COG0237	dephospho-CoA kinase activity
CSB70_RS00285	COG0195	Participates in both transcription termination and antitermination
CSB70_RS00300	COG1320	monovalent cation:proton antiporter activity
CSB70_RS00305	COG2212	antiporter activity
CSB70_RS00310	COG1863	multisubunit Na H antiporter MnhE subunit
CSB70_RS00315	COG0651	ATP synthesis coupled electron transport
CSB70_RS00320	COG1006	Multisubunit Na H antiporter MnhC subunit
CSB70_RS00325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB70_RS00325	COG2111	Na H antiporter
CSB70_RS00340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CSB70_RS00345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_RS00360	COG2226	methyltransferase
CSB70_RS00380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CSB70_RS00385	COG1074	ATP-dependent DNA helicase activity
CSB70_RS00390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_RS00395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSB70_RS00410	COG0598	Magnesium transport protein CorA
CSB70_RS00415	COG0789	Transcriptional regulator
CSB70_RS00420	COG0484	heat shock protein binding
CSB70_RS00435	COG0475	glutathione-regulated potassium exporter activity
CSB70_RS00435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_RS00440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CSB70_RS00460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_RS00470	COG4535	Mg2 and Co2 transporter CorC
CSB70_RS00475	COG0425	Belongs to the sulfur carrier protein TusA family
CSB70_RS00485	COG0644	oxidoreductase
CSB70_RS00485	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CSB70_RS00495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB70_RS00510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_RS00515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CSB70_RS00525	COG0493	'glutamate synthase
CSB70_RS00525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB70_RS00550	COG4372	Transposase
CSB70_RS00570	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CSB70_RS00585	COG0534	Mate efflux family protein
CSB70_RS00595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB70_RS00600	COG4221	oxidoreductase activity
CSB70_RS00605	COG0583	DNA-binding transcription factor activity
CSB70_RS00620	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_RS00625	COG1530	ribonuclease E activity
CSB70_RS00640	COG0546	phosphoglycolate phosphatase activity
CSB70_RS00650	COG0625	glutathione transferase activity
CSB70_RS00660	COG0583	DNA-binding transcription factor activity
CSB70_RS00705	COG0583	DNA-binding transcription factor activity
CSB70_RS00730	COG0473	3-isopropylmalate dehydrogenase activity
CSB70_RS00785	COG1301	dicarboxylic acid transport
CSB70_RS00795	COG1560	Kdo2-lipid A biosynthetic process
CSB70_RS00800	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS00805	COG0488	(ABC) transporter
CSB70_RS00810	COG2900	Belongs to the SlyX family
CSB70_RS00820	COG1733	regulation of RNA biosynthetic process
CSB70_RS00845	COG0210	DNA helicase
CSB70_RS00850	COG0724	RNA recognition motif
CSB70_RS00870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_RS00870	COG4651	solute:proton antiporter activity
CSB70_RS00895	COG0788	formyltetrahydrofolate deformylase activity
CSB70_RS01005	COG2813	Specifically methylates the guanine in position
CSB70_RS01005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_RS01015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB70_RS01025	COG4774	siderophore transport
CSB70_RS01035	COG0740	serine-type endopeptidase activity
CSB70_RS01065	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB70_RS01065	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CSB70_RS01070	COG0280	phosphate acetyltransferase
CSB70_RS01070	COG0857	belongs to the CobB CobQ family
CSB70_RS01075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CSB70_RS01085	COG0800	Aldolase
CSB70_RS01095	COG3265	gluconokinase activity
CSB70_RS01100	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS01110	COG2267	carboxylic ester hydrolase activity
CSB70_RS01125	COG0793	Belongs to the peptidase S41A family
CSB70_RS01160	COG1426	Protein conserved in bacteria
CSB70_RS01200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CSB70_RS01210	COG1162	GTPase activity
CSB70_RS01215	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CSB70_RS01230	COG1538	Outer membrane efflux protein
CSB70_RS01235	COG1136	(ABC) transporter
CSB70_RS01235	COG0577	efflux transmembrane transporter activity
CSB70_RS01240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS01265	COG0028	Belongs to the TPP enzyme family
CSB70_RS01270	COG0440	acetolactate synthase activity
CSB70_RS01305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CSB70_RS01320	COG0084	hydrolase, TatD family'
CSB70_RS01330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CSB70_RS01340	COG0583	DNA-binding transcription factor activity
CSB70_RS01350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB70_RS01355	COG2814	Major facilitator Superfamily
CSB70_RS01365	COG0697	spore germination
CSB70_RS01395	COG3622	Belongs to the hyi family
CSB70_RS01400	COG2084	Dehydrogenase
CSB70_RS01405	COG1024	Enoyl-CoA hydratase
CSB70_RS01410	COG0784	Response regulator, receiver
CSB70_RS01410	COG2205	protein histidine kinase activity
CSB70_RS01410	COG5002	protein histidine kinase activity
CSB70_RS01430	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB70_RS01440	COG3956	TIGRFAM MazG family protein
CSB70_RS01445	COG1555	photosystem II stabilization
CSB70_RS01450	COG0617	tRNA 3'-terminal CCA addition
CSB70_RS01455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CSB70_RS01475	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB70_RS01480	COG3028	Belongs to the UPF0307 family
CSB70_RS01485	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_RS01505	COG0625	glutathione transferase activity
CSB70_RS01510	COG1238	metal cluster binding
CSB70_RS01550	COG0072	phenylalanine-tRNA ligase activity
CSB70_RS01580	COG0248	Ppx GppA phosphatase
CSB70_RS01590	COG0037	tRNA processing
CSB70_RS01630	COG1764	response to oxidative stress
CSB70_RS01635	COG1846	Transcriptional regulator
CSB70_RS01645	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB70_RS01705	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CSB70_RS01710	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CSB70_RS01715	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CSB70_RS01725	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CSB70_RS01775	COG1214	PFAM Peptidase M22, glycoprotease
CSB70_RS01790	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB70_RS01810	COG4372	Transposase
CSB70_RS01815	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CSB70_RS01820	COG0561	phosphatase activity
CSB70_RS01830	COG2132	Multicopper oxidase
CSB70_RS01835	COG3667	copper resistance
CSB70_RS01850	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CSB70_RS01855	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CSB70_RS01860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CSB70_RS01890	COG1063	alcohol dehydrogenase
CSB70_RS01895	COG0583	DNA-binding transcription factor activity
CSB70_RS01900	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS01905	COG2814	Major facilitator Superfamily
CSB70_RS01910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB70_RS01920	COG1053	succinate dehydrogenase
CSB70_RS01925	COG0583	DNA-binding transcription factor activity
CSB70_RS01945	COG0583	DNA-binding transcription factor activity
CSB70_RS01980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_RS02020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CSB70_RS02040	COG0745	RESPONSE REGULATOR receiver
CSB70_RS02060	COG4372	Transposase
CSB70_RS02100	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CSB70_RS02130	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CSB70_RS02135	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CSB70_RS02160	COG0583	DNA-binding transcription factor activity
CSB70_RS02180	COG0668	transmembrane transport
CSB70_RS02190	COG2081	HI0933 family
CSB70_RS02195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CSB70_RS02225	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_RS02225	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CSB70_RS02235	COG0489	protein tyrosine kinase activity
CSB70_RS02295	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CSB70_RS02305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CSB70_RS02320	COG0730	response to heat
CSB70_RS02330	COG1196	nuclear chromosome segregation
CSB70_RS02350	COG2223	nitrite transmembrane transporter activity
CSB70_RS02355	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CSB70_RS02360	COG1877	trehalose-phosphatase activity
CSB70_RS02365	COG0596	Alpha beta hydrolase
CSB70_RS02365	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_RS02365	COG2226	methyltransferase
CSB70_RS02380	COG4106	trans-aconitate 2-methyltransferase activity
CSB70_RS02395	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CSB70_RS02400	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CSB70_RS02405	COG0009	L-threonylcarbamoyladenylate synthase
CSB70_RS02410	COG3101	peptidyl-lysine hydroxylation
CSB70_RS02415	COG1399	metal-binding, possibly nucleic acid-binding protein
CSB70_RS02440	COG1652	LysM domain
CSB70_RS02445	COG0351	phosphomethylpyrimidine kinase
CSB70_RS02445	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_RS02445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB70_RS02455	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CSB70_RS02485	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB70_RS02515	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CSB70_RS02530	COG0358	DNA primase activity
CSB70_RS02540	COG0564	pseudouridine synthase activity
CSB70_RS02565	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB70_RS02585	COG0583	DNA-binding transcription factor activity
CSB70_RS02590	COG0473	3-isopropylmalate dehydrogenase activity
CSB70_RS02600	COG0657	acetylesterase activity
CSB70_RS02610	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS02630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CSB70_RS02630	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CSB70_RS02645	COG1981	membrane
CSB70_RS02690	COG0456	acetyltransferase
CSB70_RS02700	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CSB70_RS02705	COG0492	ferredoxin-NADP+ reductase activity
CSB70_RS02710	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CSB70_RS02710	COG1674	ftsk spoiiie
CSB70_RS02715	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS02730	COG2894	cell division
CSB70_RS02745	COG0204	Acyl-transferase
CSB70_RS02750	COG2885	chlorophyll binding
CSB70_RS02755	COG0210	DNA helicase
CSB70_RS02765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB70_RS02780	COG0121	glutamine amidotransferase
CSB70_RS02805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB70_RS02810	COG0735	belongs to the Fur family
CSB70_RS02835	COG0420	3'-5' exonuclease activity
CSB70_RS02855	COG1090	epimerase
CSB70_RS02870	COG2050	protein possibly involved in aromatic compounds catabolism
CSB70_RS02880	COG2814	Major facilitator Superfamily
CSB70_RS02885	COG0405	Gamma-glutamyltransferase
CSB70_RS02910	COG0732	type I restriction modification DNA specificity domain
CSB70_RS02920	COG4372	Transposase
CSB70_RS02955	COG4372	Transposase
CSB70_RS02990	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CSB70_RS03035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB70_RS03070	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB70_RS03080	COG0402	S-adenosylhomocysteine deaminase activity
CSB70_RS03095	COG1053	succinate dehydrogenase
CSB70_RS03140	COG0583	DNA-binding transcription factor activity
CSB70_RS03195	COG0477	Major facilitator Superfamily
CSB70_RS03200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_RS03225	COG0531	amino acid
CSB70_RS03230	COG2040	homocysteine
CSB70_RS03255	COG1309	transcriptional regulator
CSB70_RS03260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_RS03265	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_RS03275	COG1607	acyl-coa hydrolase
CSB70_RS03285	COG0523	cobalamin synthesis protein
CSB70_RS03295	COG4681	YaeQ
CSB70_RS03305	COG0726	polysaccharide deacetylase
CSB70_RS03305	COG1649	PFAM Uncharacterised BCR, COG1649
CSB70_RS03310	COG1215	transferase activity, transferring glycosyl groups
CSB70_RS03320	COG1024	Enoyl-CoA hydratase
CSB70_RS03335	COG1414	Transcriptional regulator
CSB70_RS03355	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS03370	COG2271	Major facilitator Superfamily
CSB70_RS03380	COG2267	carboxylic ester hydrolase activity
CSB70_RS03385	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS03395	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS03400	COG0028	Belongs to the TPP enzyme family
CSB70_RS03410	COG0477	Major facilitator Superfamily
CSB70_RS03415	COG0242	peptide deformylase activity
CSB70_RS03420	COG2066	Belongs to the glutaminase family
CSB70_RS03425	COG2207	Transcriptional regulator
CSB70_RS03430	COG2223	nitrite transmembrane transporter activity
CSB70_RS03450	COG0583	DNA-binding transcription factor activity
CSB70_RS03455	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS03460	COG2271	Major facilitator Superfamily
CSB70_RS03465	COG3959	Transketolase, thiamine diphosphate binding domain
CSB70_RS03470	COG3958	Transketolase
CSB70_RS03480	COG0306	phosphate transporter
CSB70_RS03500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB70_RS03545	COG4181	ATPase activity
CSB70_RS03550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CSB70_RS03580	COG0583	DNA-binding transcription factor activity
CSB70_RS03590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_RS03595	COG1773	rubredoxin
CSB70_RS03645	COG2851	Citrate transporter
CSB70_RS03655	COG1253	flavin adenine dinucleotide binding
CSB70_RS03695	COG0804	urea catabolic process
CSB70_RS03705	COG0830	nickel cation binding
CSB70_RS03720	COG0742	ribosomal rna small subunit methyltransferase
CSB70_RS03725	COG0768	penicillin binding
CSB70_RS03750	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CSB70_RS03755	COG2878	Part of a membrane complex involved in electron transport
CSB70_RS03760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB70_RS03770	COG3384	dioxygenase
CSB70_RS03790	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CSB70_RS04135	COG1278	Cold shock
CSB70_RS04175	COG0006	proline dipeptidase activity
CSB70_RS04180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_RS04185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_RS04205	COG1279	arginine transmembrane transporter activity
CSB70_RS04210	COG0583	DNA-binding transcription factor activity
CSB70_RS04250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_RS04255	COG0741	lytic transglycosylase activity
CSB70_RS04255	COG1388	LysM domain
CSB70_RS04255	COG1388	LysM domain
CSB70_RS04255	COG0741	lytic transglycosylase activity
CSB70_RS04265	COG4174	ABC transporter (Permease)
CSB70_RS04270	COG4239	(ABC) transporter, permease
CSB70_RS04275	COG4172	Belongs to the ABC transporter superfamily
CSB70_RS04295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_RS04305	COG2203	Gaf domain
CSB70_RS04305	COG5001	Diguanylate cyclase
CSB70_RS04305	COG4251	negative regulation of phosphorylation
CSB70_RS04305	COG3706	GGDEF domain
CSB70_RS04315	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS04315	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_RS04330	COG4269	membrane
CSB70_RS04355	COG3209	COG3209 Rhs family protein
CSB70_RS04390	COG1113	amino acid transport
CSB70_RS04400	COG0531	amino acid
CSB70_RS04420	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS04440	COG1113	amino acid transport
CSB70_RS04475	COG0697	spore germination
CSB70_RS04480	COG2721	sulfolactate sulfo-lyase activity
CSB70_RS04485	COG2271	Major facilitator Superfamily
CSB70_RS04490	COG4948	Mandelate Racemase Muconate Lactonizing
CSB70_RS04500	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS04505	COG2186	Transcriptional regulator
CSB70_RS04530	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS04540	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS04545	COG1024	Enoyl-CoA hydratase
CSB70_RS04550	COG2814	Major facilitator Superfamily
CSB70_RS04565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_RS04580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CSB70_RS04625	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CSB70_RS04630	COG2072	flavoprotein involved in K transport
CSB70_RS04635	COG0300	oxidoreductase activity
CSB70_RS04645	COG1309	transcriptional regulator
CSB70_RS04650	COG1741	Belongs to the pirin family
CSB70_RS04665	COG2072	flavoprotein involved in K transport
CSB70_RS04675	COG2252	PERMEase
CSB70_RS04680	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CSB70_RS04685	COG3038	cytochrome b561
CSB70_RS04695	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CSB70_RS04705	COG0527	aspartate kinase activity
CSB70_RS04715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CSB70_RS04730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CSB70_RS04755	COG1765	OsmC-like protein
CSB70_RS04770	COG0542	response to heat
CSB70_RS04805	COG2885	chlorophyll binding
CSB70_RS04815	COG0625	glutathione transferase activity
CSB70_RS04820	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CSB70_RS04840	COG3634	alkyl hydroperoxide reductase activity
CSB70_RS04850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CSB70_RS04860	COG0450	alkyl hydroperoxide reductase
CSB70_RS04865	COG1643	Atp-dependent helicase
CSB70_RS04880	COG2814	Major facilitator Superfamily
CSB70_RS04885	COG3135	benzoate transporter
CSB70_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS04895	COG0543	2 iron, 2 sulfur cluster binding
CSB70_RS04895	COG0633	Ferredoxin
CSB70_RS04900	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB70_RS04905	COG4638	Rieske (2fe-2S)
CSB70_RS04910	COG0583	DNA-binding transcription factor activity
CSB70_RS04920	COG2871	sodium ion transport
CSB70_RS05005	COG1570	exodeoxyribonuclease VII activity
CSB70_RS05040	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS05045	COG1278	Cold shock
CSB70_RS05085	COG2814	Major facilitator Superfamily
CSB70_RS05225	COG3728	DNA packaging
CSB70_RS05225	COG5484	DNA packaging
CSB70_RS05365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CSB70_RS05375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CSB70_RS05380	COG1137	ATPase activity
CSB70_RS05385	COG1538	Outer membrane efflux protein
CSB70_RS05415	COG4122	O-methyltransferase activity
CSB70_RS05425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CSB70_RS05440	COG1522	sequence-specific DNA binding
CSB70_RS05445	COG5006	permease, DMT superfamily
CSB70_RS05455	COG1560	Kdo2-lipid A biosynthetic process
CSB70_RS05470	COG2814	Major facilitator Superfamily
CSB70_RS05495	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_RS05555	COG0583	DNA-binding transcription factor activity
CSB70_RS05560	COG1914	H( )-stimulated, divalent metal cation uptake system
CSB70_RS05580	COG4770	biotin carboxylase activity
CSB70_RS05585	COG0038	chloride channel
CSB70_RS05620	COG4372	Transposase
CSB70_RS05635	COG1309	transcriptional regulator
CSB70_RS05645	COG1063	alcohol dehydrogenase
CSB70_RS05660	COG0439	Biotin carboxylase
CSB70_RS05665	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS05670	COG1733	regulation of RNA biosynthetic process
CSB70_RS05680	COG0864	Transcriptional regulator
CSB70_RS05690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_RS05695	COG1116	anion transmembrane transporter activity
CSB70_RS05825	COG0590	tRNA wobble adenosine to inosine editing
CSB70_RS05830	COG2807	transmembrane transport
CSB70_RS05845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CSB70_RS05855	COG0789	Transcriptional regulator
CSB70_RS05870	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_RS05890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CSB70_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS05920	COG0531	amino acid
CSB70_RS05925	COG1760	l-serine dehydratase
CSB70_RS05930	COG2030	dehydratase
CSB70_RS05930	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS05935	COG3396	Phenylacetate-CoA oxygenase
CSB70_RS05940	COG3460	Phenylacetate-CoA oxygenase
CSB70_RS05945	COG3396	Phenylacetate-CoA oxygenase
CSB70_RS05950	COG2151	metal-sulfur cluster biosynthetic enzyme
CSB70_RS05955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_RS05960	COG1024	Enoyl-CoA hydratase
CSB70_RS05965	COG1024	Enoyl-CoA hydratase
CSB70_RS05970	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_RS05975	COG0183	Belongs to the thiolase family
CSB70_RS05980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CSB70_RS05985	COG3327	negative regulation of DNA-templated transcription, initiation
CSB70_RS05995	COG2050	protein possibly involved in aromatic compounds catabolism
CSB70_RS06045	COG1278	Cold shock
CSB70_RS06055	COG2207	Transcriptional regulator
CSB70_RS06070	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CSB70_RS06075	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CSB70_RS06080	COG2271	Major facilitator Superfamily
CSB70_RS06085	COG0753	catalase activity
CSB70_RS06090	COG3038	cytochrome b561
CSB70_RS06095	COG0583	DNA-binding transcription factor activity
CSB70_RS06105	COG1414	Transcriptional regulator
CSB70_RS06110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_RS06120	COG1840	ABC-type Fe3 transport system, periplasmic component
CSB70_RS06125	COG3842	ATPase activity
CSB70_RS06140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CSB70_RS06145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CSB70_RS06150	COG2814	Major facilitator Superfamily
CSB70_RS06155	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS06170	COG1024	Enoyl-CoA hydratase
CSB70_RS06180	COG2814	Major facilitator Superfamily
CSB70_RS06190	COG0183	Belongs to the thiolase family
CSB70_RS06195	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_RS06200	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS06205	COG1024	Enoyl-CoA hydratase
CSB70_RS06210	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS06215	COG2814	Major facilitator Superfamily
CSB70_RS06220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_RS06225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_RS06235	COG2814	Major facilitator Superfamily
CSB70_RS06245	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS06260	COG0583	DNA-binding transcription factor activity
CSB70_RS06270	COG4770	biotin carboxylase activity
CSB70_RS06275	COG1024	Enoyl-CoA hydratase
CSB70_RS06280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB70_RS06285	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS06290	COG1309	transcriptional regulator
CSB70_RS06295	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_RS06315	COG0583	DNA-binding transcription factor activity
CSB70_RS06325	COG4372	Transposase
CSB70_RS06380	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS06400	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CSB70_RS06420	COG2205	protein histidine kinase activity
CSB70_RS06420	COG0784	Response regulator, receiver
CSB70_RS06440	COG0765	amino acid transport
CSB70_RS06445	COG0765	amino acid transport
CSB70_RS06450	COG1126	abc transporter atp-binding protein
CSB70_RS06455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_RS06460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CSB70_RS06475	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS06480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CSB70_RS06485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB70_RS06490	COG1045	serine acetyltransferase
CSB70_RS06505	COG0583	DNA-binding transcription factor activity
CSB70_RS06510	COG0625	glutathione transferase activity
CSB70_RS06515	COG0625	glutathione transferase activity
CSB70_RS06520	COG0583	DNA-binding transcription factor activity
CSB70_RS06530	COG1346	cytolysis
CSB70_RS06535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS06550	COG2814	Major facilitator Superfamily
CSB70_RS06560	COG0583	DNA-binding transcription factor activity
CSB70_RS06570	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CSB70_RS06575	COG3052	prosthetic group binding
CSB70_RS06595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CSB70_RS06615	COG4372	Transposase
CSB70_RS06635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS06645	COG1294	oxidase, subunit
CSB70_RS06650	COG1271	oxidase subunit
CSB70_RS06675	COG0477	Major facilitator Superfamily
CSB70_RS06685	COG4521	taurine ABC transporter
CSB70_RS06690	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CSB70_RS06695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_RS06700	COG2175	clavaminate synthase activity
CSB70_RS06710	COG1953	Uracil, thiamine, allantoin
CSB70_RS06720	COG0583	DNA-binding transcription factor activity
CSB70_RS06730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CSB70_RS06745	COG0640	Transcriptional regulator
CSB70_RS06750	COG0798	PFAM Bile acid sodium symporter
CSB70_RS06755	COG0583	DNA-binding transcription factor activity
CSB70_RS06770	COG3634	alkyl hydroperoxide reductase activity
CSB70_RS06810	COG0436	Aminotransferase
CSB70_RS06820	COG0386	Belongs to the glutathione peroxidase family
CSB70_RS06860	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB70_RS06885	COG0012	GTP binding
CSB70_RS06890	COG2011	ABC-type metal ion transport system permease component
CSB70_RS06895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB70_RS06905	COG1464	Belongs to the NlpA lipoprotein family
CSB70_RS06935	COG0765	amino acid transport
CSB70_RS06940	COG0765	amino acid transport
CSB70_RS06945	COG1126	abc transporter atp-binding protein
CSB70_RS06955	COG1522	sequence-specific DNA binding
CSB70_RS07040	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_RS07165	COG0739	heme binding
CSB70_RS07165	COG1196	nuclear chromosome segregation
CSB70_RS07165	COG0741	lytic transglycosylase activity
CSB70_RS07250	COG1309	transcriptional regulator
CSB70_RS07270	COG0583	DNA-binding transcription factor activity
CSB70_RS07280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CSB70_RS07290	COG0697	spore germination
CSB70_RS07330	COG3121	Chaperone
CSB70_RS07335	COG3539	Fimbrial protein
CSB70_RS07365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CSB70_RS07365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CSB70_RS07410	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CSB70_RS07420	COG2353	YceI-like domain
CSB70_RS07430	COG3698	Phosphodiester glycosidase
CSB70_RS07445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CSB70_RS07450	COG0506	proline dehydrogenase activity
CSB70_RS07450	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB70_RS07450	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CSB70_RS07460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB70_RS07465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CSB70_RS07485	COG1132	(ABC) transporter
CSB70_RS07490	COG3122	Protein conserved in bacteria
CSB70_RS07495	COG3619	membrane
CSB70_RS07505	COG0640	Transcriptional regulator
CSB70_RS07515	COG2850	peptidyl-arginine hydroxylation
CSB70_RS07520	COG0424	maF-like protein
CSB70_RS07540	COG0191	fructose-bisphosphate aldolase activity
CSB70_RS07545	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB70_RS07560	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CSB70_RS07570	COG1192	Involved in chromosome partitioning
CSB70_RS07575	COG1475	DNA binding
CSB70_RS07580	COG0811	peptide transport
CSB70_RS07590	COG1132	(ABC) transporter
CSB70_RS07595	COG1663	tetraacyldisaccharide 4'-kinase activity
CSB70_RS07615	COG0084	hydrolase, TatD family'
CSB70_RS07680	COG0776	regulation of translation
CSB70_RS07710	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CSB70_RS07775	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_RS07870	COG3646	Phage regulatory protein
CSB70_RS07910	COG4372	Transposase
CSB70_RS07970	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CSB70_RS08005	COG4166	transmembrane transport
CSB70_RS08015	COG0339	signal peptide processing
CSB70_RS08025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CSB70_RS08060	COG0702	epimerase
CSB70_RS08065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB70_RS08085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB70_RS08115	COG0316	Belongs to the HesB IscA family
CSB70_RS08120	COG0822	iron-sulfur transferase activity
CSB70_RS08145	COG0776	regulation of translation
CSB70_RS08150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CSB70_RS08155	COG2207	Transcriptional regulator
CSB70_RS08160	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB70_RS08165	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS08170	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS08185	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CSB70_RS08200	COG2814	Major facilitator Superfamily
CSB70_RS08205	COG4264	IucA IucC family
CSB70_RS08210	COG4264	IucA IucC family
CSB70_RS08220	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CSB70_RS08270	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CSB70_RS08275	COG0406	alpha-ribazole phosphatase activity
CSB70_RS08290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CSB70_RS08295	COG0730	response to heat
CSB70_RS08315	COG4773	Receptor
CSB70_RS08320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_RS08335	COG1131	(ABC) transporter
CSB70_RS08340	COG0842	Transport permease protein
CSB70_RS08400	COG2226	methyltransferase
CSB70_RS08425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CSB70_RS08460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSB70_RS08470	COG0133	tryptophan synthase activity
CSB70_RS08485	COG3706	GGDEF domain
CSB70_RS08500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB70_RS08505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CSB70_RS08510	COG0022	dehydrogenase e1 component
CSB70_RS08515	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB70_RS08520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_RS08530	COG1063	alcohol dehydrogenase
CSB70_RS08535	COG3781	membrane
CSB70_RS08545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_RS08545	COG3453	Protein conserved in bacteria
CSB70_RS08555	COG0730	response to heat
CSB70_RS08570	COG3708	Transcriptional regulator
CSB70_RS08570	COG2207	Transcriptional regulator
CSB70_RS08575	COG1733	regulation of RNA biosynthetic process
CSB70_RS08580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CSB70_RS08590	COG2188	Transcriptional regulator
CSB70_RS08605	COG4521	taurine ABC transporter
CSB70_RS08610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_RS08630	COG0477	Major facilitator Superfamily
CSB70_RS08640	COG1027	Aspartate ammonia-lyase
CSB70_RS08655	COG0583	DNA-binding transcription factor activity
CSB70_RS08660	COG0583	DNA-binding transcription factor activity
CSB70_RS08665	COG0183	Belongs to the thiolase family
CSB70_RS08670	COG2031	fatty acid transporter
CSB70_RS08685	COG0583	DNA-binding transcription factor activity
CSB70_RS08710	COG2610	gluconate transmembrane transporter activity
CSB70_RS08715	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS08720	COG2207	Transcriptional regulator
CSB70_RS08735	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS08745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_RS08760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_RS08760	COG0543	2 iron, 2 sulfur cluster binding
CSB70_RS08765	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CSB70_RS08770	COG4638	Rieske (2fe-2S)
CSB70_RS08780	COG0725	ABC transporter, periplasmic molybdate-binding protein
CSB70_RS08785	COG4149	molybdate abc transporter
CSB70_RS08790	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CSB70_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS08800	COG3433	isochorismatase activity
CSB70_RS08800	COG1535	isochorismatase
CSB70_RS08865	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB70_RS08970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CSB70_RS08975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS08980	COG0745	RESPONSE REGULATOR receiver
CSB70_RS08985	COG2205	protein histidine kinase activity
CSB70_RS08995	COG2207	Transcriptional regulator
CSB70_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS09065	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CSB70_RS09145	COG4372	Transposase
CSB70_RS09175	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CSB70_RS09195	COG1120	ATPase activity
CSB70_RS09200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSB70_RS09210	COG1064	alcohol dehydrogenase
CSB70_RS09215	COG2207	Transcriptional regulator
CSB70_RS09220	COG2084	Dehydrogenase
CSB70_RS09230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CSB70_RS09240	COG0583	DNA-binding transcription factor activity
CSB70_RS09250	COG0129	dihydroxy-acid dehydratase activity
CSB70_RS09255	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS09270	COG1566	PFAM secretion protein HlyD family protein
CSB70_RS09285	COG0583	DNA-binding transcription factor activity
CSB70_RS09300	COG2188	Transcriptional regulator
CSB70_RS09360	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_RS09370	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS09380	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS09385	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS09395	COG0583	DNA-binding transcription factor activity
CSB70_RS09400	COG1309	transcriptional regulator
CSB70_RS09425	COG0789	Transcriptional regulator
CSB70_RS09440	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_RS09440	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS09455	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS09475	COG2186	Transcriptional regulator
CSB70_RS09485	COG0583	DNA-binding transcription factor activity
CSB70_RS09490	COG4948	Mandelate Racemase Muconate Lactonizing
CSB70_RS09495	COG4829	muconolactone delta-isomerase
CSB70_RS09505	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_RS09510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_RS09515	COG0183	Belongs to the thiolase family
CSB70_RS09520	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CSB70_RS09530	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS09540	COG3733	amine oxidase
CSB70_RS09550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS09570	COG4638	Rieske (2fe-2S)
CSB70_RS09590	COG0154	amidase activity
CSB70_RS09600	COG2814	Major facilitator Superfamily
CSB70_RS09625	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS09630	COG0583	DNA-binding transcription factor activity
CSB70_RS09635	COG1414	Transcriptional regulator
CSB70_RS09650	COG2391	methyltransferase activity
CSB70_RS09660	COG4993	Dehydrogenase
CSB70_RS09665	COG3659	wide pore channel activity
CSB70_RS09670	COG3420	alginic acid biosynthetic process
CSB70_RS09675	COG0710	3-dehydroquinate dehydratase activity
CSB70_RS09680	COG3485	protocatechuate 3,4-dioxygenase
CSB70_RS09685	COG3485	protocatechuate 3,4-dioxygenase
CSB70_RS09690	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CSB70_RS09695	COG2271	Major facilitator Superfamily
CSB70_RS09700	COG0596	Alpha beta hydrolase
CSB70_RS09705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CSB70_RS09710	COG0183	Belongs to the thiolase family
CSB70_RS09715	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CSB70_RS09720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CSB70_RS09730	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CSB70_RS09735	COG2323	membrane
CSB70_RS09780	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS09780	COG0446	pyridine nucleotide-disulphide oxidoreductase
CSB70_RS09805	COG0542	response to heat
CSB70_RS09810	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CSB70_RS09840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB70_RS09845	COG0569	domain protein
CSB70_RS09850	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CSB70_RS09865	COG4774	siderophore transport
CSB70_RS09870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CSB70_RS09880	COG1585	Membrane protein implicated in regulation of membrane protease activity
CSB70_RS09905	COG1294	oxidase, subunit
CSB70_RS09910	COG4890	Cyd operon protein YbgT
CSB70_RS09930	COG4372	Transposase
CSB70_RS09935	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CSB70_RS09945	COG0552	protein localization to endoplasmic reticulum
CSB70_RS09970	COG0517	IMP dehydrogenase activity
CSB70_RS09970	COG0516	GMP reductase activity
CSB70_RS09975	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB70_RS09980	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CSB70_RS09990	COG0583	DNA-binding transcription factor activity
CSB70_RS09995	COG0024	Methionine aminopeptidase
CSB70_RS10025	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CSB70_RS10025	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CSB70_RS10030	COG1105	Belongs to the carbohydrate kinase PfkB family
CSB70_RS10035	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CSB70_RS10035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB70_RS10035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CSB70_RS10055	COG3300	MHYT domain
CSB70_RS10055	COG5001	Diguanylate cyclase
CSB70_RS10080	COG2135	peptidase activity
CSB70_RS10085	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_RS10100	COG1113	amino acid transport
CSB70_RS10110	COG1522	sequence-specific DNA binding
CSB70_RS10135	COG1011	Hydrolase
CSB70_RS10140	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CSB70_RS10150	COG2137	regulation of response to DNA damage stimulus
CSB70_RS10165	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_RS10185	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CSB70_RS10200	COG0575	Belongs to the CDS family
CSB70_RS10205	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CSB70_RS10230	COG3852	Histidine kinase
CSB70_RS10235	COG2204	response regulator
CSB70_RS10295	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CSB70_RS10300	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CSB70_RS10320	COG0697	spore germination
CSB70_RS10325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS10335	COG0303	'Molybdopterin
CSB70_RS10340	COG0521	Mo-molybdopterin cofactor biosynthetic process
CSB70_RS10340	COG0315	cyclic pyranopterin monophosphate synthase activity
CSB70_RS10355	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CSB70_RS10360	COG0243	molybdopterin cofactor binding
CSB70_RS10370	COG0243	molybdopterin cofactor binding
CSB70_RS10375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_RS10380	COG2146	nitrite reductase [NAD(P)H] activity
CSB70_RS10380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_RS10390	COG0745	RESPONSE REGULATOR receiver
CSB70_RS10395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_RS10395	COG1116	anion transmembrane transporter activity
CSB70_RS10415	COG0511	ligase activity, forming carbon-carbon bonds
CSB70_RS10430	COG2814	Major facilitator Superfamily
CSB70_RS10470	COG0069	glutamate synthase activity
CSB70_RS10500	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CSB70_RS10510	COG1454	alcohol dehydrogenase
CSB70_RS10515	COG0824	Thioesterase
CSB70_RS10525	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CSB70_RS10550	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CSB70_RS10555	COG2030	dehydratase
CSB70_RS10565	COG0183	Belongs to the thiolase family
CSB70_RS10575	COG0583	DNA-binding transcription factor activity
CSB70_RS10580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CSB70_RS10590	COG1522	sequence-specific DNA binding
CSB70_RS10595	COG3135	benzoate transporter
CSB70_RS10605	COG4372	Transposase
CSB70_RS10625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CSB70_RS10640	COG0589	response to stress
CSB70_RS10645	COG0488	(ABC) transporter
CSB70_RS10650	COG0488	(ABC) transporter
CSB70_RS10675	COG4773	Receptor
CSB70_RS10705	COG0668	transmembrane transport
CSB70_RS10715	COG1309	transcriptional regulator
CSB70_RS10735	COG1605	Chorismate mutase
CSB70_RS10775	COG0308	aminopeptidase N
CSB70_RS10795	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CSB70_RS10805	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_RS10810	COG1454	alcohol dehydrogenase
CSB70_RS10830	COG0531	amino acid
CSB70_RS10835	COG4303	Ethanolamine ammonia lyase large subunit
CSB70_RS10840	COG4302	ethanolamine ammonia-lyase activity
CSB70_RS10845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB70_RS10845	COG0519	Catalyzes the synthesis of GMP from XMP
CSB70_RS10850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSB70_RS10860	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CSB70_RS10875	COG0697	spore germination
CSB70_RS10880	COG1923	regulation of RNA biosynthetic process
CSB70_RS10890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CSB70_RS10895	COG0802	atpase or kinase
CSB70_RS10915	COG1187	pseudouridine synthase activity
CSB70_RS10930	COG0583	DNA-binding transcription factor activity
CSB70_RS10945	COG2814	Major facilitator Superfamily
CSB70_RS10950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CSB70_RS10980	COG0729	surface antigen
CSB70_RS11000	COG0174	glutamine synthetase
CSB70_RS11005	COG0745	RESPONSE REGULATOR receiver
CSB70_RS11010	COG2205	protein histidine kinase activity
CSB70_RS11020	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CSB70_RS11025	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CSB70_RS11050	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_RS11060	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS11075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_RS11080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_RS11095	COG3328	transposase activity
CSB70_RS11105	COG0583	DNA-binding transcription factor activity
CSB70_RS11125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB70_RS11135	COG3658	cytochrome
CSB70_RS11140	COG1215	transferase activity, transferring glycosyl groups
CSB70_RS11145	COG0726	polysaccharide deacetylase
CSB70_RS11145	COG1649	PFAM Uncharacterised BCR, COG1649
CSB70_RS11170	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CSB70_RS11175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CSB70_RS11185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CSB70_RS11210	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_RS11215	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CSB70_RS11225	COG1305	Transglutaminase-like
CSB70_RS11235	COG2308	Evidence 4 Homologs of previously reported genes of
CSB70_RS11265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CSB70_RS11270	COG0138	bifunctional purine biosynthesis protein purh
CSB70_RS11275	COG0151	Belongs to the GarS family
CSB70_RS11280	COG1464	Belongs to the NlpA lipoprotein family
CSB70_RS11285	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CSB70_RS11290	COG2011	ABC-type metal ion transport system permease component
CSB70_RS11295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_RS11305	COG1301	dicarboxylic acid transport
CSB70_RS11330	COG4372	Transposase
CSB70_RS11350	COG1794	racemase activity, acting on amino acids and derivatives
CSB70_RS11370	COG0745	RESPONSE REGULATOR receiver
CSB70_RS11375	COG0642	Histidine kinase
CSB70_RS11380	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB70_RS11390	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CSB70_RS11430	COG2351	hydroxyisourate hydrolase activity
CSB70_RS11440	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CSB70_RS11440	COG3008	intermembrane lipid transfer
CSB70_RS11445	COG2995	paraquat-inducible protein a
CSB70_RS11460	COG2985	domain, Protein
CSB70_RS11490	COG1051	belongs to the nudix hydrolase family
CSB70_RS11495	COG0477	Major facilitator Superfamily
CSB70_RS11545	COG2186	Transcriptional regulator
CSB70_RS11555	COG0786	glutamate:sodium symporter activity
CSB70_RS11560	COG3243	poly(R)-hydroxyalkanoic acid synthase
CSB70_RS11585	COG3111	PFAM Bacterial OB fold (BOF) protein
CSB70_RS11640	COG3328	transposase activity
CSB70_RS11655	COG3210	domain, Protein
CSB70_RS11660	COG2831	hemolysin activation secretion protein
CSB70_RS11685	COG0515	serine threonine protein kinase
CSB70_RS11685	COG2815	serine threonine protein kinase
CSB70_RS11715	COG1610	YqeY-like protein
CSB70_RS11720	COG4783	chaperone-mediated protein folding
CSB70_RS11745	COG1286	toxin biosynthetic process
CSB70_RS11775	COG0778	Nitroreductase
CSB70_RS11785	COG0513	Belongs to the DEAD box helicase family
CSB70_RS11805	COG2363	Small membrane protein
CSB70_RS11835	COG1234	tRNA 3'-trailer cleavage
CSB70_RS11840	COG2195	Cleaves the N-terminal amino acid of tripeptides
CSB70_RS11850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CSB70_RS11860	COG2819	hydrolase of the alpha beta superfamily
CSB70_RS11865	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS11870	COG1301	dicarboxylic acid transport
CSB70_RS11880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CSB70_RS11885	COG3139	Protein of unknown function (DUF1315)
CSB70_RS11890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CSB70_RS11895	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CSB70_RS11905	COG0494	nUDIX hydrolase
CSB70_RS11915	COG0642	Histidine kinase
CSB70_RS11930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CSB70_RS11940	COG1720	tRNA m6t6A37 methyltransferase activity
CSB70_RS11955	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS11960	COG0826	peptidase U32
CSB70_RS11965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CSB70_RS11975	COG4598	ABC transporter
CSB70_RS11980	COG4160	amino acid transport
CSB70_RS11985	COG4215	(ABC) transporter
CSB70_RS12000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS12290	COG0305	Participates in initiation and elongation during chromosome replication
CSB70_RS12360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CSB70_RS12390	COG0582	viral genome integration into host DNA
CSB70_RS12395	COG1131	(ABC) transporter
CSB70_RS12400	COG0842	Transport permease protein
CSB70_RS12415	COG0772	Belongs to the SEDS family
CSB70_RS12420	COG2951	lytic endotransglycosylase activity
CSB70_RS12445	COG2207	Transcriptional regulator
CSB70_RS12460	COG0052	Belongs to the universal ribosomal protein uS2 family
CSB70_RS12465	COG0024	Methionine aminopeptidase
CSB70_RS12475	COG2223	nitrite transmembrane transporter activity
CSB70_RS12485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_RS12490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CSB70_RS12495	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS12510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CSB70_RS12515	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CSB70_RS12520	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB70_RS12540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB70_RS12545	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CSB70_RS12550	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CSB70_RS12585	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CSB70_RS12595	COG0174	glutamine synthetase
CSB70_RS12610	COG0512	Glutamine amidotransferase of anthranilate synthase
CSB70_RS12645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CSB70_RS12655	COG0302	gtp cyclohydrolase
CSB70_RS12685	COG3739	integral membrane protein
CSB70_RS12710	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CSB70_RS12715	COG1132	(ABC) transporter
CSB70_RS12720	COG1132	(ABC) transporter
CSB70_RS12735	COG3433	isochorismatase activity
CSB70_RS12735	COG1535	isochorismatase
CSB70_RS12740	COG1021	2,3-dihydroxybenzoate-AMP ligase
CSB70_RS12745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_RS12755	COG4774	siderophore transport
CSB70_RS12760	COG4607	ABC-type enterochelin transport system periplasmic component
CSB70_RS12765	COG4604	ABC transporter, ATP-binding protein
CSB70_RS12770	COG4605	iron ion homeostasis
CSB70_RS12775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CSB70_RS12780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_RS12795	COG2964	Protein conserved in bacteria
CSB70_RS12805	COG1741	Belongs to the pirin family
CSB70_RS12840	COG2879	small protein
CSB70_RS12845	COG1966	Carbon starvation protein
CSB70_RS12865	COG4943	cyclic-guanylate-specific phosphodiesterase activity
CSB70_RS12890	COG1067	ATP-dependent peptidase activity
CSB70_RS12895	COG0583	DNA-binding transcription factor activity
CSB70_RS12920	COG1686	Belongs to the peptidase S11 family
CSB70_RS12925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CSB70_RS12970	COG4372	Transposase
CSB70_RS12980	COG0616	signal peptide processing
CSB70_RS12985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CSB70_RS12995	COG0573	inorganic phosphate transmembrane transporter activity
CSB70_RS13000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CSB70_RS13005	COG1113	amino acid transport
CSB70_RS13010	COG3961	Belongs to the TPP enzyme family
CSB70_RS13015	COG1522	sequence-specific DNA binding
CSB70_RS13025	COG0076	glutamate decarboxylase activity
CSB70_RS13030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB70_RS13045	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS13055	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_RS13090	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_RS13115	COG0612	Peptidase, M16
CSB70_RS13125	COG1823	symporter activity
CSB70_RS13130	COG0583	DNA-binding transcription factor activity
CSB70_RS13135	COG0477	Major facilitator Superfamily
CSB70_RS13160	COG1187	pseudouridine synthase activity
CSB70_RS13175	COG1686	Belongs to the peptidase S11 family
CSB70_RS13180	COG1252	NADH dehydrogenase
CSB70_RS13190	COG0415	Belongs to the DNA photolyase family
CSB70_RS13205	COG1215	transferase activity, transferring glycosyl groups
CSB70_RS13235	COG2070	2-Nitropropane dioxygenase
CSB70_RS13290	COG0556	nucleotide-excision repair
CSB70_RS13310	COG0436	Aminotransferase
CSB70_RS13335	COG0443	Heat shock 70 kDa protein
CSB70_RS13365	COG4221	oxidoreductase activity
CSB70_RS13375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CSB70_RS13380	COG1381	Involved in DNA repair and RecF pathway recombination
CSB70_RS13390	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CSB70_RS13405	COG0681	Belongs to the peptidase S26 family
CSB70_RS13420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CSB70_RS13440	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CSB70_RS13445	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CSB70_RS13450	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CSB70_RS13460	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CSB70_RS13465	COG4208	sulfate ABC transporter
CSB70_RS13470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CSB70_RS13475	COG0583	DNA-binding transcription factor activity
CSB70_RS13480	COG4625	pathogenesis
CSB70_RS13495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CSB70_RS13510	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CSB70_RS13520	COG1051	belongs to the nudix hydrolase family
CSB70_RS13520	COG1056	cytidyltransferase-related domain
CSB70_RS13525	COG1024	Enoyl-CoA hydratase
CSB70_RS13535	COG2814	Major facilitator Superfamily
CSB70_RS13540	COG0047	phosphoribosylformylglycinamidine synthase activity
CSB70_RS13540	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CSB70_RS13560	COG1473	amidohydrolase
CSB70_RS13565	COG0824	Thioesterase
CSB70_RS13585	COG0823	Involved in the tonB-independent uptake of proteins
CSB70_RS13605	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CSB70_RS13650	COG0628	permease
CSB70_RS13660	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CSB70_RS13665	COG0596	Alpha beta hydrolase
CSB70_RS13670	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CSB70_RS13670	COG0616	signal peptide processing
CSB70_RS13680	COG0658	competence protein
CSB70_RS13680	COG2333	competence protein COMEC
CSB70_RS13685	COG1136	(ABC) transporter
CSB70_RS13690	COG4591	ABC-type transport system involved in lipoprotein release permease component
CSB70_RS13720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS13740	COG0463	Glycosyl transferase, family 2
CSB70_RS13770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB70_RS13775	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS13780	COG2267	carboxylic ester hydrolase activity
CSB70_RS13790	COG0019	diaminopimelate decarboxylase activity
CSB70_RS13800	COG1113	amino acid transport
CSB70_RS13805	COG1115	amino acid carrier protein
CSB70_RS13830	COG3339	Conserved Protein
CSB70_RS13835	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CSB70_RS13840	COG0243	molybdopterin cofactor binding
CSB70_RS13845	COG1929	Belongs to the glycerate kinase type-1 family
CSB70_RS13860	COG0778	Nitroreductase
CSB70_RS13910	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_RS13930	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CSB70_RS13960	COG0741	lytic transglycosylase activity
CSB70_RS13980	COG0584	glycerophosphoryl diester phosphodiesterase
CSB70_RS13985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CSB70_RS13995	COG0582	viral genome integration into host DNA
CSB70_RS14010	COG3293	Transposase
CSB70_RS14015	COG1063	alcohol dehydrogenase
CSB70_RS14025	COG3179	chitinase
CSB70_RS14060	COG1196	nuclear chromosome segregation
CSB70_RS14060	COG0741	lytic transglycosylase activity
CSB70_RS14060	COG0739	heme binding
CSB70_RS14185	COG5410	chromosome segregation
CSB70_RS14365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB70_RS14370	COG1597	lipid kinase activity
CSB70_RS14385	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CSB70_RS14390	COG0477	Major facilitator Superfamily
CSB70_RS14440	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CSB70_RS14445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CSB70_RS14470	COG0505	Belongs to the CarA family
CSB70_RS14485	COG1309	transcriptional regulator
CSB70_RS14490	COG0251	oxidation-reduction process
CSB70_RS14500	COG0589	response to stress
CSB70_RS14515	COG2843	Capsule synthesis protein
CSB70_RS14555	COG2321	neutral zinc metallopeptidase
CSB70_RS14560	COG2354	Protein conserved in bacteria
CSB70_RS14580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CSB70_RS14605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CSB70_RS14610	COG1053	succinate dehydrogenase
CSB70_RS14615	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CSB70_RS14620	COG2009	succinate dehydrogenase
CSB70_RS14660	COG2921	Belongs to the UPF0250 family
CSB70_RS14665	COG0321	lipoyl(octanoyl) transferase activity
CSB70_RS14680	COG0531	amino acid
CSB70_RS14690	COG1733	regulation of RNA biosynthetic process
CSB70_RS14695	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CSB70_RS14700	COG1648	precorrin-2 dehydrogenase activity
CSB70_RS14700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CSB70_RS14715	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CSB70_RS14745	COG0671	phosphoesterase, PA-phosphatase related
CSB70_RS14750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS14760	COG1538	Outer membrane efflux protein
CSB70_RS14765	COG0393	Putative heavy-metal-binding
CSB70_RS14770	COG0393	Putative heavy-metal-binding
CSB70_RS14780	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS14790	COG0525	valine-tRNA ligase activity
CSB70_RS14795	COG2226	methyltransferase
CSB70_RS14810	COG0583	DNA-binding transcription factor activity
CSB70_RS14820	COG0004	ammonium transporteR
CSB70_RS14830	COG0642	Histidine kinase
CSB70_RS14835	COG0745	RESPONSE REGULATOR receiver
CSB70_RS14840	COG2194	sulfuric ester hydrolase activity
CSB70_RS14860	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB70_RS14875	COG2315	Protein conserved in bacteria
CSB70_RS14880	COG0142	geranyltranstransferase activity
CSB70_RS14885	COG2828	Protein conserved in bacteria
CSB70_RS14890	COG1113	amino acid transport
CSB70_RS14910	COG2207	Transcriptional regulator
CSB70_RS14935	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS14945	COG0560	Phosphoserine phosphatase
CSB70_RS14955	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CSB70_RS14965	COG1530	ribonuclease E activity
CSB70_RS14970	COG0424	maF-like protein
CSB70_RS14975	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CSB70_RS14980	COG1792	Involved in formation and maintenance of cell shape
CSB70_RS14985	COG1077	Cell shape determining protein MreB Mrl
CSB70_RS14990	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_RS15005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_RS15015	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CSB70_RS15040	COG3590	peptidase
CSB70_RS15045	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CSB70_RS15050	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CSB70_RS15055	COG1752	Esterase of the alpha-beta hydrolase superfamily
CSB70_RS15060	COG1115	amino acid carrier protein
CSB70_RS15080	COG2814	Major facilitator Superfamily
CSB70_RS15085	COG1289	transmembrane transporter activity
CSB70_RS15095	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CSB70_RS15135	COG1376	ErfK ybiS ycfS ynhG family protein
CSB70_RS15140	COG2832	Protein of unknown function (DUF454)
CSB70_RS15150	COG5510	response to toxic substance
CSB70_RS15165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CSB70_RS15180	COG0840	transmembrane signaling receptor activity
CSB70_RS15220	COG3422	double-strand break repair
CSB70_RS15225	COG2824	Alkylphosphonate utilization operon protein PhnA
CSB70_RS15230	COG3189	MarR family transcriptional regulator
CSB70_RS15240	COG0354	folic acid binding
CSB70_RS15245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_RS15255	COG0679	Auxin Efflux Carrier
CSB70_RS15260	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS15265	COG4772	TonB-dependent receptor
CSB70_RS15270	COG2094	Belongs to the DNA glycosylase MPG family
CSB70_RS15295	COG1217	gtp-binding protein TYPA
CSB70_RS15300	COG2233	PERMEase
CSB70_RS15310	COG0833	amino acid
CSB70_RS15315	COG1690	Belongs to the RtcB family
CSB70_RS15325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CSB70_RS15325	COG2885	chlorophyll binding
CSB70_RS15335	COG0183	Belongs to the thiolase family
CSB70_RS15355	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CSB70_RS15375	COG2207	Transcriptional regulator
CSB70_RS15380	COG0183	Belongs to the thiolase family
CSB70_RS15385	COG1250	3-hydroxyacyl-CoA dehydrogenase
CSB70_RS15385	COG1024	Enoyl-CoA hydratase
CSB70_RS15410	COG1272	protein, Hemolysin III
CSB70_RS15415	COG0477	Major facilitator Superfamily
CSB70_RS15430	COG0450	alkyl hydroperoxide reductase
CSB70_RS15450	COG0285	dihydrofolate synthase activity
CSB70_RS15500	COG2096	Adenosyltransferase
CSB70_RS15505	COG0584	glycerophosphoryl diester phosphodiesterase
CSB70_RS15520	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CSB70_RS15525	COG0745	RESPONSE REGULATOR receiver
CSB70_RS15530	COG2205	protein histidine kinase activity
CSB70_RS15540	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS15545	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS15615	COG4372	Transposase
CSB70_RS15635	COG1091	dTDP-4-dehydrorhamnose reductase activity
CSB70_RS15655	COG0726	polysaccharide deacetylase
CSB70_RS15670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CSB70_RS15675	COG2205	protein histidine kinase activity
CSB70_RS15725	COG1862	Preprotein translocase
CSB70_RS15735	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CSB70_RS15740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CSB70_RS15750	COG3781	membrane
CSB70_RS15755	COG0613	PHP domain protein
CSB70_RS15765	COG2350	Protein conserved in bacteria
CSB70_RS15795	COG1607	acyl-coa hydrolase
CSB70_RS15855	COG2199	diguanylate cyclase activity
CSB70_RS15865	COG1408	metallophosphoesterase
CSB70_RS15870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CSB70_RS15880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CSB70_RS15900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CSB70_RS15905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CSB70_RS15910	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
CSB70_RS15920	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CSB70_RS15930	COG2969	positive regulation of protein catabolic process
CSB70_RS15970	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS15975	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CSB70_RS15990	COG1309	transcriptional regulator
CSB70_RS15995	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS16045	COG1183	phosphatidylcholine synthase activity
CSB70_RS16050	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CSB70_RS16080	COG0739	heme binding
CSB70_RS16080	COG0741	lytic transglycosylase activity
CSB70_RS16080	COG1196	nuclear chromosome segregation
CSB70_RS16090	COG1702	phosphate starvation-inducible protein PhoH
CSB70_RS16125	COG1295	ribonuclease BN
CSB70_RS16130	COG0697	spore germination
CSB70_RS16135	COG2169	Transcriptional regulator
CSB70_RS16140	COG0179	Fumarylacetoacetate (FAA) hydrolase
CSB70_RS16185	COG0557	exoribonuclease II activity
CSB70_RS16190	COG0339	signal peptide processing
CSB70_RS16195	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CSB70_RS16225	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CSB70_RS16230	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS16385	COG0626	cystathionine gamma-synthase activity
CSB70_RS16390	COG0433	COG0433 Predicted ATPase
CSB70_RS16400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CSB70_RS16400	COG1017	nitric oxide dioxygenase activity
CSB70_RS16405	COG1959	2 iron, 2 sulfur cluster binding
CSB70_RS16420	COG1301	dicarboxylic acid transport
CSB70_RS16425	COG1946	Acyl-CoA thioesterase
CSB70_RS16445	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CSB70_RS16450	COG1040	competence protein
CSB70_RS16455	COG0494	nUDIX hydrolase
CSB70_RS16465	COG0598	Magnesium transport protein CorA
CSB70_RS16475	COG2854	intermembrane phospholipid transfer
CSB70_RS16485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CSB70_RS16490	COG1127	ABC transporter
CSB70_RS16495	COG0513	Belongs to the DEAD box helicase family
CSB70_RS16515	COG0408	coproporphyrinogen oxidase activity
CSB70_RS16530	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS16540	COG1983	PspC domain protein
CSB70_RS16545	COG0517	IMP dehydrogenase activity
CSB70_RS16595	COG0583	DNA-binding transcription factor activity
CSB70_RS16635	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS16645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CSB70_RS16650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CSB70_RS16655	COG0833	amino acid
CSB70_RS16685	COG1192	Involved in chromosome partitioning
CSB70_RS16690	COG0628	permease
CSB70_RS16700	COG1289	transmembrane transporter activity
CSB70_RS16715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS16720	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CSB70_RS16730	COG0277	FAD linked oxidase domain protein
CSB70_RS16735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CSB70_RS16760	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CSB70_RS16765	COG5380	lipid catabolic process
CSB70_RS16785	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CSB70_RS16835	COG0194	GDP metabolic process
CSB70_RS16850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CSB70_RS16870	COG3307	-O-antigen
CSB70_RS16885	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CSB70_RS16890	COG1704	LemA family
CSB70_RS16900	COG0493	'glutamate synthase
CSB70_RS16905	COG0067	glutamate synthase
CSB70_RS16905	COG0069	glutamate synthase activity
CSB70_RS16905	COG0070	glutamate synthase
CSB70_RS16955	COG2226	methyltransferase
CSB70_RS16970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CSB70_RS16975	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CSB70_RS17020	COG0833	amino acid
CSB70_RS17105	COG0488	(ABC) transporter
CSB70_RS17110	COG2873	o-acetylhomoserine
CSB70_RS17115	COG4221	oxidoreductase activity
CSB70_RS17120	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_RS17145	COG0427	acetyl-CoA hydrolase
CSB70_RS17175	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CSB70_RS17205	COG2329	Antibiotic biosynthesis monooxygenase
CSB70_RS17220	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CSB70_RS17285	COG2249	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS17295	COG1733	regulation of RNA biosynthetic process
CSB70_RS17335	COG0667	Aldo Keto reductase
CSB70_RS17355	COG0583	DNA-binding transcription factor activity
CSB70_RS17360	COG2814	Major facilitator Superfamily
CSB70_RS17390	COG4372	Transposase
CSB70_RS17410	COG1335	isochorismatase
CSB70_RS17420	COG1012	belongs to the aldehyde dehydrogenase family
CSB70_RS17425	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CSB70_RS17435	COG1113	amino acid transport
CSB70_RS17445	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CSB70_RS17460	COG2814	Major facilitator Superfamily
CSB70_RS17470	COG0351	phosphomethylpyrimidine kinase
CSB70_RS17470	COG0352	thiamine-phosphate diphosphorylase activity
CSB70_RS17470	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CSB70_RS17490	COG1309	transcriptional regulator
CSB70_RS17495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CSB70_RS17515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CSB70_RS17525	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CSB70_RS17530	COG3162	membrane
CSB70_RS17535	COG0784	Response regulator, receiver
CSB70_RS17535	COG2198	Histidine kinase
CSB70_RS17535	COG2205	protein histidine kinase activity
CSB70_RS17560	COG1522	sequence-specific DNA binding
CSB70_RS17565	COG1335	isochorismatase
CSB70_RS17570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_RS17580	COG0668	transmembrane transport
CSB70_RS17585	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CSB70_RS17590	COG1519	Transferase
CSB70_RS17595	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS17615	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CSB70_RS17640	COG0426	domain, Protein
CSB70_RS17640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CSB70_RS17645	COG4774	siderophore transport
CSB70_RS17655	COG4372	Transposase
CSB70_RS17680	COG0508	dehydrogenase complex catalyzes the overall conversion of
CSB70_RS17690	COG4942	peptidase
CSB70_RS17705	COG4372	Transposase
CSB70_RS17720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CSB70_RS17730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CSB70_RS17750	COG0189	ligase activity
CSB70_RS17770	COG0708	Exodeoxyribonuclease III
CSB70_RS17775	COG1393	Belongs to the ArsC family
CSB70_RS17790	COG3706	GGDEF domain
CSB70_RS17825	COG2351	hydroxyisourate hydrolase activity
CSB70_RS17830	COG2233	PERMEase
CSB70_RS17840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CSB70_RS17850	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CSB70_RS17855	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS17865	COG3150	esterase
CSB70_RS17880	COG1388	LysM domain
CSB70_RS17880	COG0791	NLP P60 protein
CSB70_RS17895	COG2918	glutathione biosynthetic process
CSB70_RS17910	COG2733	membrane
CSB70_RS17915	COG0436	Aminotransferase
CSB70_RS17920	COG0534	Mate efflux family protein
CSB70_RS18025	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CSB70_RS18030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CSB70_RS18040	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CSB70_RS18045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CSB70_RS18060	COG0010	Belongs to the arginase family
CSB70_RS18090	COG2188	Transcriptional regulator
CSB70_RS18100	COG0523	cobalamin synthesis protein
CSB70_RS18110	COG1113	amino acid transport
CSB70_RS18120	COG0625	glutathione transferase activity
CSB70_RS18140	COG1683	Conserved Protein
CSB70_RS18145	COG0534	Mate efflux family protein
CSB70_RS18150	COG0385	Bile acid
CSB70_RS18155	COG1335	isochorismatase
CSB70_RS18160	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_RS18180	COG2116	formate transmembrane transporter activity
CSB70_RS18185	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CSB70_RS18190	COG2133	pyrroloquinoline quinone binding
CSB70_RS18195	COG2983	Belongs to the UPF0260 family
CSB70_RS18215	COG1194	a g-specific adenine glycosylase
CSB70_RS18230	COG2818	Glycosylase
CSB70_RS18235	COG1064	alcohol dehydrogenase
CSB70_RS18240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS18255	COG0583	DNA-binding transcription factor activity
CSB70_RS18260	COG0656	L-ascorbic acid biosynthetic process
CSB70_RS18265	COG2814	Major facilitator Superfamily
CSB70_RS18300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CSB70_RS18315	COG2233	PERMEase
CSB70_RS18355	COG0733	neurotransmitter:sodium symporter activity
CSB70_RS18380	COG4372	Transposase
CSB70_RS18415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CSB70_RS18420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CSB70_RS18425	COG0596	Alpha beta hydrolase
CSB70_RS18460	COG0488	(ABC) transporter
CSB70_RS18465	COG0586	Pfam SNARE associated Golgi protein
CSB70_RS18475	COG0187	DNA topoisomerase II activity
CSB70_RS18485	COG0592	DNA-directed DNA polymerase activity
CSB70_RS18510	COG0706	membrane insertase activity
CSB70_RS18525	COG1230	cation diffusion facilitator family transporter
CSB70_RS18530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_RS18545	COG0402	S-adenosylhomocysteine deaminase activity
CSB70_RS18555	COG0754	glutathionylspermidine amidase activity
CSB70_RS18565	COG0861	Integral membrane protein TerC family
CSB70_RS18570	COG0671	phosphoesterase, PA-phosphatase related
CSB70_RS18580	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CSB70_RS18600	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CSB70_RS18605	COG2951	lytic endotransglycosylase activity
CSB70_RS18655	COG0657	acetylesterase activity
CSB70_RS18660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CSB70_RS18700	COG1047	Peptidyl-prolyl cis-trans
CSB70_RS18710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CSB70_RS18715	COG0196	riboflavin kinase activity
CSB70_RS18725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CSB70_RS18730	COG1309	transcriptional regulator
CSB70_RS18735	COG1116	anion transmembrane transporter activity
CSB70_RS18740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CSB70_RS18745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CSB70_RS18750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_RS18755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CSB70_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
CSB70_RS18780	COG0546	phosphoglycolate phosphatase activity
CSB70_RS18840	COG3023	N-Acetylmuramoyl-L-alanine amidase
CSB70_RS18845	COG0728	peptidoglycan biosynthetic process
CSB70_RS18870	COG1596	polysaccharide export
CSB70_RS18875	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CSB70_RS18930	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CSB70_RS18935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CSB70_RS18940	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CSB70_RS18955	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CSB70_RS18965	COG2186	Transcriptional regulator
CSB70_RS18975	COG0277	FAD linked oxidase domain protein
CSB70_RS18980	COG1448	Aminotransferase
CSB70_RS18985	COG1802	Transcriptional regulator
CSB70_RS19000	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CSB70_RS19005	COG1196	nuclear chromosome segregation
CSB70_RS19070	COG0564	pseudouridine synthase activity
CSB70_RS19110	COG0251	oxidation-reduction process
CSB70_RS19115	COG1113	amino acid transport
CSB70_RS19120	COG1113	amino acid transport
CSB70_RS19140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CSB70_RS19145	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS19150	COG1024	Enoyl-CoA hydratase
CSB70_RS19155	COG1024	Enoyl-CoA hydratase
CSB70_RS19160	COG0477	Major facilitator Superfamily
CSB70_RS19180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CSB70_RS19185	COG1846	Transcriptional regulator
CSB70_RS19190	COG3916	Acyl-homoserine-lactone synthase
CSB70_RS19200	COG2197	response regulator
CSB70_RS19210	COG1960	acyl-CoA dehydrogenase activity
CSB70_RS19215	COG4221	oxidoreductase activity
CSB70_RS19215	COG3321	synthase
CSB70_RS19215	COG0300	oxidoreductase activity
CSB70_RS19215	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CSB70_RS19255	COG0271	Belongs to the BolA IbaG family
CSB70_RS19265	COG1192	Involved in chromosome partitioning
CSB70_RS19280	COG0586	Pfam SNARE associated Golgi protein
CSB70_RS19285	COG2259	Doxx family
CSB70_RS19290	COG4399	Belongs to the UPF0754 family
CSB70_RS19295	COG0519	Catalyzes the synthesis of GMP from XMP
CSB70_RS19295	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CSB70_RS19340	COG0281	malic enzyme
CSB70_RS19345	COG2837	iron assimilation
CSB70_RS19355	COG1280	lysine exporter protein (LysE YggA)
CSB70_RS19360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CSB70_RS19365	COG1121	(ABC) transporter
CSB70_RS19430	COG0386	Belongs to the glutathione peroxidase family
CSB70_RS19445	COG4372	Transposase
CSB70_RS19465	COG1309	transcriptional regulator
CSB70_RS19470	COG0697	spore germination
CSB70_RS19480	COG0758	DNA mediated transformation
CSB70_RS19515	COG1309	transcriptional regulator
CSB70_RS19545	COG4372	Transposase
CSB70_RS19565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CSB70_RS19575	COG0655	NAD(P)H dehydrogenase (quinone) activity
CSB70_RS19620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CSB70_RS19640	COG1253	flavin adenine dinucleotide binding
CSB70_RS19650	COG2860	membrane
CSB70_RS19655	COG0477	Major facilitator Superfamily
CSB70_RS19665	COG0318	PFAM AMP-dependent synthetase and ligase
CSB70_RS19680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CSB70_RS19695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CSB70_RS19705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CSB70_RS19710	COG0606	chelatase, subunit chli
CSB70_RS19740	COG2072	flavoprotein involved in K transport
CSB70_RS19745	COG0492	ferredoxin-NADP+ reductase activity
CSB70_RS19750	COG0431	NADPH-dependent FMN reductase
CSB70_RS19755	COG0798	PFAM Bile acid sodium symporter
CSB70_RS19765	COG0640	Transcriptional regulator
CSB70_RS19775	COG0589	response to stress
CSB70_RS19780	COG0659	secondary active sulfate transmembrane transporter activity
CSB70_RS19800	COG0606	chelatase, subunit chli
CSB70_RS19810	COG0347	Belongs to the P(II) protein family
CSB70_RS19815	COG0004	ammonium transporteR
CSB70_RS19825	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB70_RS19825	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CSB70_RS19865	COG0795	lipopolysaccharide-transporting ATPase activity
CSB70_RS19870	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CSB70_RS19875	COG0793	Belongs to the peptidase S41A family
CSB70_RS19890	COG2197	response regulator
CSB70_RS19900	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CSB70_RS19910	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CSB70_RS19915	COG4974	Belongs to the 'phage' integrase family
CSB70_RS19940	COG0772	Belongs to the SEDS family
CSB70_RS19945	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CSB70_RS19950	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CSB70_RS19955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CSB70_RS19980	COG0697	spore germination
CSB70_RS19985	COG1538	Outer membrane efflux protein
CSB70_RS20005	COG3275	phosphorelay sensor kinase activity
CSB70_RS20015	COG0181	hydroxymethylbilane synthase activity
CSB70_RS20060	COG1716	ATPase activity
CSB70_RS20065	COG0546	phosphoglycolate phosphatase activity
CSB70_RS20225	COG1192	Involved in chromosome partitioning
CSB70_RS20250	COG2026	Addiction module toxin, RelE StbE family
CSB70_RS20260	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CSB70_RS20345	COG1846	Transcriptional regulator
CSB70_RS20370	COG1846	Transcriptional regulator
CSB70_RS20375	COG1764	response to oxidative stress
CSB70_RS20380	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20420	COG1764	response to oxidative stress
CSB70_RS20425	COG1846	Transcriptional regulator
CSB70_RS20450	COG1846	Transcriptional regulator
CSB70_RS20455	COG1764	response to oxidative stress
CSB70_RS20495	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20500	COG1764	response to oxidative stress
CSB70_RS20505	COG1846	Transcriptional regulator
CSB70_RS20530	COG1846	Transcriptional regulator
CSB70_RS20535	COG1764	response to oxidative stress
CSB70_RS20575	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20580	COG1764	response to oxidative stress
CSB70_RS20585	COG1846	Transcriptional regulator
CSB70_RS20610	COG1846	Transcriptional regulator
CSB70_RS20615	COG1764	response to oxidative stress
CSB70_RS20620	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20660	COG1764	response to oxidative stress
CSB70_RS20665	COG1846	Transcriptional regulator
CSB70_RS20690	COG1846	Transcriptional regulator
CSB70_RS20695	COG1764	response to oxidative stress
CSB70_RS20735	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20740	COG1764	response to oxidative stress
CSB70_RS20745	COG1846	Transcriptional regulator
CSB70_RS20770	COG1846	Transcriptional regulator
CSB70_RS20775	COG1764	response to oxidative stress
CSB70_RS20780	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20820	COG1764	response to oxidative stress
CSB70_RS20825	COG1846	Transcriptional regulator
CSB70_RS20850	COG1846	Transcriptional regulator
CSB70_RS20855	COG1764	response to oxidative stress
CSB70_RS20860	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CSB70_RS20955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CSB70_RS21125	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CSB70_RS21130	COG3657	addiction module killer protein
CSB70_RS21170	COG4221	oxidoreductase activity
CSB70_RS21175	COG0583	DNA-binding transcription factor activity
CSB70_RS21180	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CSB70_RS21185	COG0604	alcohol dehydrogenase
CSB70_RS21185	COG3321	synthase
CSB70_RS21240	COG1063	alcohol dehydrogenase
CSB70_RS21255	COG4372	Transposase
CSB70_RS21270	COG0475	glutathione-regulated potassium exporter activity
CSB70_RS21270	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CSB70_RS21305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CSB70_RS21315	COG1979	alcohol dehydrogenase
CSB70_RS21325	COG1902	pentaerythritol trinitrate reductase activity
CSB70_RS21335	COG1309	transcriptional regulator
CSB70_RS21340	COG2130	NADP-dependent
CSB70_RS21355	COG0582	viral genome integration into host DNA
CSB70_RS21360	COG3328	transposase activity
CSB70_RS21400	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CSB70_RS21460	COG0358	DNA primase activity