locus-tag	class	description
AM462_RS00035	COG1215	transferase activity, transferring glycosyl groups
AM462_RS00050	COG0415	Belongs to the DNA photolyase family
AM462_RS00060	COG1252	NADH dehydrogenase
AM462_RS00065	COG1686	Belongs to the peptidase S11 family
AM462_RS00080	COG1187	pseudouridine synthase activity
AM462_RS00105	COG0477	Major facilitator Superfamily
AM462_RS00110	COG0583	DNA-binding transcription factor activity
AM462_RS00115	COG1823	symporter activity
AM462_RS00125	COG0612	Peptidase, M16
AM462_RS00155	COG1203	CRISPR-associated helicase, Cas3
AM462_RS00180	COG0352	thiamine-phosphate diphosphorylase activity
AM462_RS00215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_RS00230	COG1309	transcriptional regulator
AM462_RS00240	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM462_RS00245	COG0076	glutamate decarboxylase activity
AM462_RS00255	COG1522	sequence-specific DNA binding
AM462_RS00260	COG3961	Belongs to the TPP enzyme family
AM462_RS00265	COG1113	amino acid transport
AM462_RS00270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM462_RS00275	COG0573	inorganic phosphate transmembrane transporter activity
AM462_RS00285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM462_RS00290	COG0616	signal peptide processing
AM462_RS00325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM462_RS00330	COG1686	Belongs to the peptidase S11 family
AM462_RS00355	COG0583	DNA-binding transcription factor activity
AM462_RS00360	COG1067	ATP-dependent peptidase activity
AM462_RS00385	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM462_RS00405	COG1966	Carbon starvation protein
AM462_RS00410	COG2879	small protein
AM462_RS00420	COG0583	DNA-binding transcription factor activity
AM462_RS00425	COG0006	proline dipeptidase activity
AM462_RS00430	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_RS00435	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_RS00445	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS00450	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_RS00455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_RS00455	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AM462_RS00510	COG1741	Belongs to the pirin family
AM462_RS00520	COG2964	Protein conserved in bacteria
AM462_RS00535	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_RS00540	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM462_RS00545	COG4605	iron ion homeostasis
AM462_RS00550	COG4604	ABC transporter, ATP-binding protein
AM462_RS00555	COG4607	ABC-type enterochelin transport system periplasmic component
AM462_RS00560	COG4774	siderophore transport
AM462_RS00570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_RS00575	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM462_RS00580	COG3433	isochorismatase activity
AM462_RS00580	COG1535	isochorismatase
AM462_RS00595	COG1132	(ABC) transporter
AM462_RS00600	COG1132	(ABC) transporter
AM462_RS00605	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM462_RS00615	COG1169	isochorismate synthase
AM462_RS00630	COG3739	integral membrane protein
AM462_RS00655	COG0302	gtp cyclohydrolase
AM462_RS00665	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM462_RS00695	COG0308	aminopeptidase N
AM462_RS00700	COG0512	Glutamine amidotransferase of anthranilate synthase
AM462_RS00715	COG0174	glutamine synthetase
AM462_RS00725	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM462_RS00760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM462_RS00765	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM462_RS00770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM462_RS00790	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM462_RS00795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM462_RS00800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM462_RS00815	COG1960	acyl-CoA dehydrogenase activity
AM462_RS00820	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM462_RS00825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_RS00835	COG2223	nitrite transmembrane transporter activity
AM462_RS00845	COG0024	Methionine aminopeptidase
AM462_RS00850	COG0052	Belongs to the universal ribosomal protein uS2 family
AM462_RS00865	COG2207	Transcriptional regulator
AM462_RS00890	COG2951	lytic endotransglycosylase activity
AM462_RS00895	COG0772	Belongs to the SEDS family
AM462_RS00910	COG0842	Transport permease protein
AM462_RS00915	COG1131	(ABC) transporter
AM462_RS00920	COG0582	viral genome integration into host DNA
AM462_RS01240	COG0739	heme binding
AM462_RS01335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS01355	COG4215	(ABC) transporter
AM462_RS01360	COG4160	amino acid transport
AM462_RS01365	COG4598	ABC transporter
AM462_RS01375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM462_RS01380	COG0826	peptidase U32
AM462_RS01385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_RS01400	COG1720	tRNA m6t6A37 methyltransferase activity
AM462_RS01410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM462_RS01425	COG0642	Histidine kinase
AM462_RS01435	COG0494	nUDIX hydrolase
AM462_RS01445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM462_RS01450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM462_RS01455	COG3139	Protein of unknown function (DUF1315)
AM462_RS01460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM462_RS01470	COG1301	dicarboxylic acid transport
AM462_RS01475	COG1960	acyl-CoA dehydrogenase activity
AM462_RS01480	COG2819	hydrolase of the alpha beta superfamily
AM462_RS01490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM462_RS01500	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM462_RS01505	COG1234	tRNA 3'-trailer cleavage
AM462_RS01530	COG2363	Small membrane protein
AM462_RS01550	COG0513	Belongs to the DEAD box helicase family
AM462_RS01560	COG0778	Nitroreductase
AM462_RS01590	COG1286	toxin biosynthetic process
AM462_RS01615	COG4783	chaperone-mediated protein folding
AM462_RS01620	COG1610	YqeY-like protein
AM462_RS01720	COG3111	PFAM Bacterial OB fold (BOF) protein
AM462_RS01745	COG3243	poly(R)-hydroxyalkanoic acid synthase
AM462_RS01750	COG0786	glutamate:sodium symporter activity
AM462_RS01760	COG0583	DNA-binding transcription factor activity
AM462_RS01770	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS01785	COG2186	Transcriptional regulator
AM462_RS01845	COG0477	Major facilitator Superfamily
AM462_RS01870	COG2995	paraquat-inducible protein a
AM462_RS01875	COG3008	intermembrane lipid transfer
AM462_RS01875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM462_RS01885	COG2351	hydroxyisourate hydrolase activity
AM462_RS01925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM462_RS01935	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AM462_RS01940	COG0642	Histidine kinase
AM462_RS01945	COG0745	RESPONSE REGULATOR receiver
AM462_RS01965	COG1794	racemase activity, acting on amino acids and derivatives
AM462_RS01995	COG1301	dicarboxylic acid transport
AM462_RS02005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_RS02010	COG2011	ABC-type metal ion transport system permease component
AM462_RS02015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM462_RS02020	COG1464	Belongs to the NlpA lipoprotein family
AM462_RS02025	COG0151	Belongs to the GarS family
AM462_RS02030	COG0138	bifunctional purine biosynthesis protein purh
AM462_RS02035	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM462_RS02065	COG2308	Evidence 4 Homologs of previously reported genes of
AM462_RS02075	COG1305	Transglutaminase-like
AM462_RS02085	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM462_RS02090	COG0305	Participates in initiation and elongation during chromosome replication
AM462_RS02115	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM462_RS02125	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM462_RS02130	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM462_RS02155	COG1649	PFAM Uncharacterised BCR, COG1649
AM462_RS02155	COG0726	polysaccharide deacetylase
AM462_RS02160	COG1215	transferase activity, transferring glycosyl groups
AM462_RS02165	COG3658	cytochrome
AM462_RS02175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_RS02195	COG0583	DNA-binding transcription factor activity
AM462_RS02215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_RS02220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_RS02240	COG1960	acyl-CoA dehydrogenase activity
AM462_RS02245	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_RS02250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS02275	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM462_RS02280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM462_RS02290	COG2205	protein histidine kinase activity
AM462_RS02295	COG0745	RESPONSE REGULATOR receiver
AM462_RS02300	COG0174	glutamine synthetase
AM462_RS02320	COG0729	surface antigen
AM462_RS02350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM462_RS02355	COG2814	Major facilitator Superfamily
AM462_RS02445	COG4397	Mu-like prophage major head subunit gpT
AM462_RS02460	COG5005	Phage virion morphogenesis
AM462_RS02465	COG2369	cell adhesion
AM462_RS02470	COG4383	Mu-like prophage protein gp29
AM462_RS02480	COG4373	Mu-like prophage FluMu protein gp28
AM462_RS02545	COG3267	Type II secretory pathway component ExeA
AM462_RS02545	COG3409	Peptidoglycan-binding domain 1 protein
AM462_RS02615	COG0583	DNA-binding transcription factor activity
AM462_RS02630	COG1187	pseudouridine synthase activity
AM462_RS02650	COG0802	atpase or kinase
AM462_RS02655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM462_RS02665	COG1923	regulation of RNA biosynthetic process
AM462_RS02670	COG0697	spore germination
AM462_RS02695	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM462_RS02700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM462_RS02700	COG0519	Catalyzes the synthesis of GMP from XMP
AM462_RS02705	COG4302	ethanolamine ammonia-lyase activity
AM462_RS02710	COG4303	Ethanolamine ammonia lyase large subunit
AM462_RS02715	COG0531	amino acid
AM462_RS02735	COG1454	alcohol dehydrogenase
AM462_RS02740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM462_RS02765	COG0308	aminopeptidase N
AM462_RS02770	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS02810	COG1605	Chorismate mutase
AM462_RS02830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AM462_RS02850	COG1309	transcriptional regulator
AM462_RS02860	COG0668	transmembrane transport
AM462_RS02895	COG4773	Receptor
AM462_RS02915	COG0488	(ABC) transporter
AM462_RS02920	COG0589	response to stress
AM462_RS02935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM462_RS02945	COG3135	benzoate transporter
AM462_RS02950	COG1522	sequence-specific DNA binding
AM462_RS02960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM462_RS02965	COG0583	DNA-binding transcription factor activity
AM462_RS02975	COG0183	Belongs to the thiolase family
AM462_RS02985	COG2030	dehydratase
AM462_RS02990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM462_RS03005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM462_RS03015	COG0824	Thioesterase
AM462_RS03020	COG1454	alcohol dehydrogenase
AM462_RS03030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM462_RS03050	COG0069	glutamate synthase activity
AM462_RS03095	COG0511	ligase activity, forming carbon-carbon bonds
AM462_RS03115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_RS03115	COG1116	anion transmembrane transporter activity
AM462_RS03120	COG0745	RESPONSE REGULATOR receiver
AM462_RS03130	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_RS03130	COG2146	nitrite reductase [NAD(P)H] activity
AM462_RS03135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_RS03140	COG0243	molybdopterin cofactor binding
AM462_RS03150	COG0243	molybdopterin cofactor binding
AM462_RS03155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM462_RS03170	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM462_RS03170	COG0315	cyclic pyranopterin monophosphate synthase activity
AM462_RS03175	COG0303	'Molybdopterin
AM462_RS03190	COG0697	spore germination
AM462_RS03210	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM462_RS03215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM462_RS03275	COG2204	response regulator
AM462_RS03280	COG3852	Histidine kinase
AM462_RS03305	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM462_RS03310	COG0575	Belongs to the CDS family
AM462_RS03345	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM462_RS03360	COG2137	regulation of response to DNA damage stimulus
AM462_RS03370	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM462_RS03375	COG1011	Hydrolase
AM462_RS03400	COG1522	sequence-specific DNA binding
AM462_RS03410	COG1113	amino acid transport
AM462_RS03425	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS03430	COG2135	peptidase activity
AM462_RS03445	COG3300	MHYT domain
AM462_RS03445	COG5001	Diguanylate cyclase
AM462_RS03465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM462_RS03465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM462_RS03465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM462_RS03470	COG1105	Belongs to the carbohydrate kinase PfkB family
AM462_RS03475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM462_RS03475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM462_RS03505	COG0024	Methionine aminopeptidase
AM462_RS03510	COG0583	DNA-binding transcription factor activity
AM462_RS03520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM462_RS03525	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM462_RS03530	COG0516	GMP reductase activity
AM462_RS03530	COG0517	IMP dehydrogenase activity
AM462_RS03555	COG0552	protein localization to endoplasmic reticulum
AM462_RS03565	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AM462_RS03575	COG4890	Cyd operon protein YbgT
AM462_RS03580	COG1294	oxidase, subunit
AM462_RS03595	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM462_RS03605	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM462_RS03625	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM462_RS03630	COG0569	domain protein
AM462_RS03635	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM462_RS03665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM462_RS03670	COG0542	response to heat
AM462_RS03695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_RS03695	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS03740	COG2323	membrane
AM462_RS03745	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM462_RS03755	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_RS03760	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_RS03765	COG0183	Belongs to the thiolase family
AM462_RS03770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM462_RS03775	COG0596	Alpha beta hydrolase
AM462_RS03780	COG2271	Major facilitator Superfamily
AM462_RS03785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM462_RS03790	COG3485	protocatechuate 3,4-dioxygenase
AM462_RS03795	COG3485	protocatechuate 3,4-dioxygenase
AM462_RS03800	COG0710	3-dehydroquinate dehydratase activity
AM462_RS03805	COG3420	alginic acid biosynthetic process
AM462_RS03810	COG3659	wide pore channel activity
AM462_RS03815	COG4993	Dehydrogenase
AM462_RS03825	COG2391	methyltransferase activity
AM462_RS03840	COG1414	Transcriptional regulator
AM462_RS03845	COG0583	DNA-binding transcription factor activity
AM462_RS03850	COG1960	acyl-CoA dehydrogenase activity
AM462_RS03875	COG2814	Major facilitator Superfamily
AM462_RS03895	COG0154	amidase activity
AM462_RS03915	COG4638	Rieske (2fe-2S)
AM462_RS03925	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS03935	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS03945	COG3733	amine oxidase
AM462_RS03955	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS03965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_RS03970	COG0183	Belongs to the thiolase family
AM462_RS03980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_RS03985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_RS03995	COG4829	muconolactone delta-isomerase
AM462_RS04000	COG4948	Mandelate Racemase Muconate Lactonizing
AM462_RS04005	COG0583	DNA-binding transcription factor activity
AM462_RS04015	COG2186	Transcriptional regulator
AM462_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS04050	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_RS04050	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS04090	COG1309	transcriptional regulator
AM462_RS04105	COG4689	acetoacetate decarboxylase
AM462_RS04115	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS04135	COG1335	isochorismatase
AM462_RS04140	COG0583	DNA-binding transcription factor activity
AM462_RS04150	COG0475	glutathione-regulated potassium exporter activity
AM462_RS04150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_RS04160	COG1473	amidohydrolase
AM462_RS04230	COG2188	Transcriptional regulator
AM462_RS04330	COG0583	DNA-binding transcription factor activity
AM462_RS04345	COG1566	PFAM secretion protein HlyD family protein
AM462_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS04365	COG0129	dihydroxy-acid dehydratase activity
AM462_RS04375	COG0583	DNA-binding transcription factor activity
AM462_RS04380	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM462_RS04390	COG2084	Dehydrogenase
AM462_RS04405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM462_RS04465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM462_RS04480	COG0556	nucleotide-excision repair
AM462_RS04520	COG1073	alpha beta
AM462_RS04530	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS04545	COG2207	Transcriptional regulator
AM462_RS04555	COG2205	protein histidine kinase activity
AM462_RS04560	COG0745	RESPONSE REGULATOR receiver
AM462_RS04565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS04570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM462_RS04575	COG1538	Outer membrane efflux protein
AM462_RS04585	COG2072	flavoprotein involved in K transport
AM462_RS04600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_RS04680	COG3539	Fimbrial protein
AM462_RS04705	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM462_RS04715	COG0753	catalase activity
AM462_RS04730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM462_RS04795	COG3433	isochorismatase activity
AM462_RS04795	COG1535	isochorismatase
AM462_RS04800	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS04805	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM462_RS04810	COG4149	molybdate abc transporter
AM462_RS04820	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM462_RS04830	COG4638	Rieske (2fe-2S)
AM462_RS04835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM462_RS04840	COG0543	2 iron, 2 sulfur cluster binding
AM462_RS04840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_RS04855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS04865	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS04880	COG2207	Transcriptional regulator
AM462_RS04885	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS04890	COG2610	gluconate transmembrane transporter activity
AM462_RS04900	COG0583	DNA-binding transcription factor activity
AM462_RS04915	COG2031	fatty acid transporter
AM462_RS04920	COG0183	Belongs to the thiolase family
AM462_RS04925	COG0583	DNA-binding transcription factor activity
AM462_RS04930	COG0583	DNA-binding transcription factor activity
AM462_RS04945	COG1027	Aspartate ammonia-lyase
AM462_RS04955	COG0477	Major facilitator Superfamily
AM462_RS04975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_RS04980	COG4521	taurine ABC transporter
AM462_RS04995	COG2188	Transcriptional regulator
AM462_RS05005	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM462_RS05010	COG1733	regulation of RNA biosynthetic process
AM462_RS05015	COG2207	Transcriptional regulator
AM462_RS05015	COG3708	Transcriptional regulator
AM462_RS05030	COG0730	response to heat
AM462_RS05040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_RS05040	COG3453	Protein conserved in bacteria
AM462_RS05050	COG3781	membrane
AM462_RS05055	COG1063	alcohol dehydrogenase
AM462_RS05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_RS05070	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM462_RS05075	COG0022	dehydrogenase e1 component
AM462_RS05080	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM462_RS05085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM462_RS05100	COG3706	GGDEF domain
AM462_RS05115	COG0133	tryptophan synthase activity
AM462_RS05125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM462_RS05160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM462_RS05185	COG2226	methyltransferase
AM462_RS05240	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM462_RS05245	COG4773	Receptor
AM462_RS05265	COG0730	response to heat
AM462_RS05270	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM462_RS05285	COG0406	alpha-ribazole phosphatase activity
AM462_RS05290	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM462_RS05305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM462_RS05335	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM462_RS05345	COG4264	IucA IucC family
AM462_RS05350	COG4264	IucA IucC family
AM462_RS05355	COG2814	Major facilitator Superfamily
AM462_RS05370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM462_RS05385	COG1960	acyl-CoA dehydrogenase activity
AM462_RS05390	COG1960	acyl-CoA dehydrogenase activity
AM462_RS05395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM462_RS05400	COG2207	Transcriptional regulator
AM462_RS05405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM462_RS05410	COG0776	regulation of translation
AM462_RS05435	COG0822	iron-sulfur transferase activity
AM462_RS05440	COG0316	Belongs to the HesB IscA family
AM462_RS05470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM462_RS05490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM462_RS05495	COG0702	epimerase
AM462_RS05530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM462_RS05540	COG0339	signal peptide processing
AM462_RS05560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
AM462_RS05585	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM462_RS05590	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM462_RS05620	COG0776	regulation of translation
AM462_RS05685	COG0084	hydrolase, TatD family'
AM462_RS05705	COG1663	tetraacyldisaccharide 4'-kinase activity
AM462_RS05710	COG1132	(ABC) transporter
AM462_RS05720	COG0811	peptide transport
AM462_RS05725	COG1475	DNA binding
AM462_RS05730	COG1192	Involved in chromosome partitioning
AM462_RS05740	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM462_RS05755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM462_RS05760	COG0191	fructose-bisphosphate aldolase activity
AM462_RS05780	COG0424	maF-like protein
AM462_RS05785	COG2850	peptidyl-arginine hydroxylation
AM462_RS05795	COG0640	Transcriptional regulator
AM462_RS05805	COG3619	membrane
AM462_RS05810	COG3122	Protein conserved in bacteria
AM462_RS05815	COG1132	(ABC) transporter
AM462_RS05835	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM462_RS05840	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM462_RS05850	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM462_RS05850	COG0506	proline dehydrogenase activity
AM462_RS05850	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM462_RS05855	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM462_RS05870	COG3698	Phosphodiester glycosidase
AM462_RS05880	COG2353	YceI-like domain
AM462_RS05890	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM462_RS05935	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM462_RS05935	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM462_RS05960	COG3539	Fimbrial protein
AM462_RS05965	COG3121	Chaperone
AM462_RS05995	COG0697	spore germination
AM462_RS06005	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM462_RS06015	COG0583	DNA-binding transcription factor activity
AM462_RS06035	COG1309	transcriptional regulator
AM462_RS06050	COG1522	sequence-specific DNA binding
AM462_RS06060	COG1126	abc transporter atp-binding protein
AM462_RS06065	COG0765	amino acid transport
AM462_RS06070	COG0765	amino acid transport
AM462_RS06100	COG1464	Belongs to the NlpA lipoprotein family
AM462_RS06110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM462_RS06115	COG2011	ABC-type metal ion transport system permease component
AM462_RS06120	COG0012	GTP binding
AM462_RS06145	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM462_RS06185	COG0386	Belongs to the glutathione peroxidase family
AM462_RS06195	COG0436	Aminotransferase
AM462_RS06200	COG1301	dicarboxylic acid transport
AM462_RS06235	COG3634	alkyl hydroperoxide reductase activity
AM462_RS06250	COG0583	DNA-binding transcription factor activity
AM462_RS06255	COG0798	PFAM Bile acid sodium symporter
AM462_RS06260	COG0640	Transcriptional regulator
AM462_RS06275	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM462_RS06285	COG0583	DNA-binding transcription factor activity
AM462_RS06295	COG1953	Uracil, thiamine, allantoin
AM462_RS06305	COG2175	clavaminate synthase activity
AM462_RS06310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_RS06315	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AM462_RS06320	COG4521	taurine ABC transporter
AM462_RS06330	COG0477	Major facilitator Superfamily
AM462_RS06355	COG1271	oxidase subunit
AM462_RS06360	COG1294	oxidase, subunit
AM462_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_RS06390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM462_RS06410	COG3052	prosthetic group binding
AM462_RS06415	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM462_RS06425	COG2814	Major facilitator Superfamily
AM462_RS06440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_RS06445	COG1346	cytolysis
AM462_RS06455	COG0583	DNA-binding transcription factor activity
AM462_RS06460	COG0625	glutathione transferase activity
AM462_RS06465	COG0625	glutathione transferase activity
AM462_RS06470	COG0583	DNA-binding transcription factor activity
AM462_RS06485	COG1045	serine acetyltransferase
AM462_RS06490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM462_RS06495	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM462_RS06500	COG1280	lysine exporter protein (LysE YggA)
AM462_RS06510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_RS06515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_RS06520	COG1126	abc transporter atp-binding protein
AM462_RS06525	COG0765	amino acid transport
AM462_RS06530	COG0765	amino acid transport
AM462_RS06550	COG0784	Response regulator, receiver
AM462_RS06550	COG2205	protein histidine kinase activity
AM462_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS06635	COG0583	DNA-binding transcription factor activity
AM462_RS06655	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_RS06660	COG1309	transcriptional regulator
AM462_RS06665	COG1960	acyl-CoA dehydrogenase activity
AM462_RS06670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM462_RS06675	COG1024	Enoyl-CoA hydratase
AM462_RS06680	COG4770	biotin carboxylase activity
AM462_RS06690	COG0583	DNA-binding transcription factor activity
AM462_RS06705	COG1960	acyl-CoA dehydrogenase activity
AM462_RS06715	COG2814	Major facilitator Superfamily
AM462_RS06725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM462_RS06730	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM462_RS06735	COG2814	Major facilitator Superfamily
AM462_RS06740	COG1960	acyl-CoA dehydrogenase activity
AM462_RS06745	COG1024	Enoyl-CoA hydratase
AM462_RS06750	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS06755	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_RS06760	COG0183	Belongs to the thiolase family
AM462_RS06770	COG2814	Major facilitator Superfamily
AM462_RS06780	COG1024	Enoyl-CoA hydratase
AM462_RS06790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_RS06795	COG1960	acyl-CoA dehydrogenase activity
AM462_RS06800	COG2814	Major facilitator Superfamily
AM462_RS06805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM462_RS06810	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM462_RS06825	COG3842	ATPase activity
AM462_RS06830	COG1840	ABC-type Fe3 transport system, periplasmic component
AM462_RS06840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_RS06845	COG1414	Transcriptional regulator
AM462_RS06855	COG0583	DNA-binding transcription factor activity
AM462_RS06860	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM462_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS06875	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM462_RS06885	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS06890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_RS06895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS06900	COG2267	carboxylic ester hydrolase activity
AM462_RS06920	COG3038	cytochrome b561
AM462_RS06925	COG0753	catalase activity
AM462_RS06930	COG2271	Major facilitator Superfamily
AM462_RS06935	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM462_RS06940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_RS06970	COG1278	Cold shock
AM462_RS07010	COG0210	DNA helicase
AM462_RS07015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM462_RS07020	COG2050	protein possibly involved in aromatic compounds catabolism
AM462_RS07030	COG3327	negative regulation of DNA-templated transcription, initiation
AM462_RS07035	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM462_RS07040	COG0183	Belongs to the thiolase family
AM462_RS07045	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_RS07050	COG1024	Enoyl-CoA hydratase
AM462_RS07055	COG1024	Enoyl-CoA hydratase
AM462_RS07060	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
AM462_RS07070	COG3396	Phenylacetate-CoA oxygenase
AM462_RS07075	COG3460	Phenylacetate-CoA oxygenase
AM462_RS07080	COG3396	Phenylacetate-CoA oxygenase
AM462_RS07085	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS07085	COG2030	dehydratase
AM462_RS07090	COG1760	l-serine dehydratase
AM462_RS07095	COG0531	amino acid
AM462_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS07125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM462_RS07145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_RS07160	COG0789	Transcriptional regulator
AM462_RS07170	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM462_RS07185	COG2807	transmembrane transport
AM462_RS07190	COG0590	tRNA wobble adenosine to inosine editing
AM462_RS07320	COG1116	anion transmembrane transporter activity
AM462_RS07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM462_RS07335	COG0864	Transcriptional regulator
AM462_RS07345	COG1733	regulation of RNA biosynthetic process
AM462_RS07350	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_RS07355	COG0439	Biotin carboxylase
AM462_RS07370	COG1063	alcohol dehydrogenase
AM462_RS07380	COG1309	transcriptional regulator
AM462_RS07410	COG0038	chloride channel
AM462_RS07415	COG4770	biotin carboxylase activity
AM462_RS07435	COG1914	H( )-stimulated, divalent metal cation uptake system
AM462_RS07440	COG0583	DNA-binding transcription factor activity
AM462_RS07465	COG3209	COG3209 Rhs family protein
AM462_RS07515	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM462_RS07530	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS07540	COG2814	Major facilitator Superfamily
AM462_RS07555	COG1560	Kdo2-lipid A biosynthetic process
AM462_RS07565	COG5006	permease, DMT superfamily
AM462_RS07570	COG1522	sequence-specific DNA binding
AM462_RS07585	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM462_RS07595	COG4122	O-methyltransferase activity
AM462_RS07625	COG1538	Outer membrane efflux protein
AM462_RS07630	COG1137	ATPase activity
AM462_RS07635	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM462_RS07645	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM462_RS07700	COG5434	Belongs to the glycosyl hydrolase 28 family
AM462_RS07720	COG3566	protein conserved in bacteria
AM462_RS07740	COG3567	Phage-associated protein, HI1409 family
AM462_RS07745	COG5410	chromosome segregation
AM462_RS07820	COG2814	Major facilitator Superfamily
AM462_RS07860	COG1278	Cold shock
AM462_RS07865	COG1280	lysine exporter protein (LysE YggA)
AM462_RS07900	COG1570	exodeoxyribonuclease VII activity
AM462_RS07955	COG0583	DNA-binding transcription factor activity
AM462_RS07960	COG4638	Rieske (2fe-2S)
AM462_RS07965	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM462_RS07970	COG0543	2 iron, 2 sulfur cluster binding
AM462_RS07970	COG0633	Ferredoxin
AM462_RS07975	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS07980	COG3135	benzoate transporter
AM462_RS07985	COG2814	Major facilitator Superfamily
AM462_RS08000	COG1643	Atp-dependent helicase
AM462_RS08005	COG0450	alkyl hydroperoxide reductase
AM462_RS08015	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM462_RS08025	COG3634	alkyl hydroperoxide reductase activity
AM462_RS08045	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM462_RS08050	COG0625	glutathione transferase activity
AM462_RS08060	COG2885	chlorophyll binding
AM462_RS08095	COG0542	response to heat
AM462_RS08110	COG1765	OsmC-like protein
AM462_RS08120	COG0667	Aldo Keto reductase
AM462_RS08135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM462_RS08145	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM462_RS08155	COG0527	aspartate kinase activity
AM462_RS08165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM462_RS08175	COG3038	cytochrome b561
AM462_RS08180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM462_RS08185	COG2252	PERMEase
AM462_RS08195	COG2072	flavoprotein involved in K transport
AM462_RS08210	COG1741	Belongs to the pirin family
AM462_RS08225	COG1309	transcriptional regulator
AM462_RS08235	COG0300	oxidoreductase activity
AM462_RS08240	COG2072	flavoprotein involved in K transport
AM462_RS08245	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM462_RS08290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_RS08305	COG2814	Major facilitator Superfamily
AM462_RS08310	COG1024	Enoyl-CoA hydratase
AM462_RS08315	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS08325	COG1960	acyl-CoA dehydrogenase activity
AM462_RS08350	COG2186	Transcriptional regulator
AM462_RS08355	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS08365	COG4948	Mandelate Racemase Muconate Lactonizing
AM462_RS08370	COG2271	Major facilitator Superfamily
AM462_RS08375	COG2721	sulfolactate sulfo-lyase activity
AM462_RS08380	COG0697	spore germination
AM462_RS08410	COG1113	amino acid transport
AM462_RS08430	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS08460	COG1113	amino acid transport
AM462_RS08500	COG3209	COG3209 Rhs family protein
AM462_RS08540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AM462_RS08580	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM462_RS08590	COG2184	nucleotidyltransferase activity
AM462_RS08615	COG3152	Membrane
AM462_RS08685	COG0582	viral genome integration into host DNA
AM462_RS08695	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_RS08695	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS08705	COG2203	Gaf domain
AM462_RS08705	COG3706	GGDEF domain
AM462_RS08705	COG4251	negative regulation of phosphorylation
AM462_RS08705	COG5001	Diguanylate cyclase
AM462_RS08715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM462_RS08770	COG4172	Belongs to the ABC transporter superfamily
AM462_RS08775	COG4239	(ABC) transporter, permease
AM462_RS08780	COG4174	ABC transporter (Permease)
AM462_RS08790	COG0741	lytic transglycosylase activity
AM462_RS08790	COG1388	LysM domain
AM462_RS08790	COG0741	lytic transglycosylase activity
AM462_RS08790	COG1388	LysM domain
AM462_RS08795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM462_RS08835	COG0583	DNA-binding transcription factor activity
AM462_RS08840	COG1279	arginine transmembrane transporter activity
AM462_RS08860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_RS08865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_RS08870	COG0006	proline dipeptidase activity
AM462_RS08910	COG1278	Cold shock
AM462_RS08965	COG0739	heme binding
AM462_RS08980	COG3561	AntA/AntB antirepressor
AM462_RS09095	COG5410	chromosome segregation
AM462_RS09195	COG3620	sequence-specific DNA binding
AM462_RS09275	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM462_RS09295	COG3384	dioxygenase
AM462_RS09305	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM462_RS09310	COG2878	Part of a membrane complex involved in electron transport
AM462_RS09315	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM462_RS09340	COG0768	penicillin binding
AM462_RS09345	COG0742	ribosomal rna small subunit methyltransferase
AM462_RS09360	COG0830	nickel cation binding
AM462_RS09370	COG0804	urea catabolic process
AM462_RS09410	COG1253	flavin adenine dinucleotide binding
AM462_RS09420	COG2851	Citrate transporter
AM462_RS09485	COG1061	Type III restriction enzyme res subunit
AM462_RS09505	COG1773	rubredoxin
AM462_RS09510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_RS09520	COG0583	DNA-binding transcription factor activity
AM462_RS09550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AM462_RS09555	COG4181	ATPase activity
AM462_RS09600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM462_RS09620	COG0306	phosphate transporter
AM462_RS09630	COG3958	Transketolase
AM462_RS09635	COG3959	Transketolase, thiamine diphosphate binding domain
AM462_RS09640	COG2271	Major facilitator Superfamily
AM462_RS09645	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS09650	COG0583	DNA-binding transcription factor activity
AM462_RS09670	COG2223	nitrite transmembrane transporter activity
AM462_RS09675	COG2207	Transcriptional regulator
AM462_RS09680	COG2066	Belongs to the glutaminase family
AM462_RS09685	COG0242	peptide deformylase activity
AM462_RS09690	COG0477	Major facilitator Superfamily
AM462_RS09700	COG0028	Belongs to the TPP enzyme family
AM462_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS09720	COG2267	carboxylic ester hydrolase activity
AM462_RS09730	COG2271	Major facilitator Superfamily
AM462_RS09735	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM462_RS09745	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS09765	COG1414	Transcriptional regulator
AM462_RS09780	COG1024	Enoyl-CoA hydratase
AM462_RS09790	COG1215	transferase activity, transferring glycosyl groups
AM462_RS09795	COG0726	polysaccharide deacetylase
AM462_RS09795	COG1649	PFAM Uncharacterised BCR, COG1649
AM462_RS09805	COG4681	YaeQ
AM462_RS09815	COG0523	cobalamin synthesis protein
AM462_RS09830	COG1061	Type III restriction enzyme res subunit
AM462_RS09855	COG1607	acyl-coa hydrolase
AM462_RS09865	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_RS09870	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_RS09875	COG1309	transcriptional regulator
AM462_RS09900	COG2040	homocysteine
AM462_RS09905	COG0531	amino acid
AM462_RS09960	COG1595	DNA-templated transcription, initiation
AM462_RS09970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_RS09975	COG0477	Major facilitator Superfamily
AM462_RS09995	COG0084	hydrolase, TatD family'
AM462_RS10040	COG1061	Type III restriction enzyme res subunit
AM462_RS10055	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS10060	COG0589	response to stress
AM462_RS10105	COG0405	Gamma-glutamyltransferase
AM462_RS10110	COG2814	Major facilitator Superfamily
AM462_RS10120	COG2050	protein possibly involved in aromatic compounds catabolism
AM462_RS10135	COG1090	epimerase
AM462_RS10155	COG0420	3'-5' exonuclease activity
AM462_RS10180	COG0735	belongs to the Fur family
AM462_RS10185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM462_RS10210	COG0121	glutamine amidotransferase
AM462_RS10225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_RS10235	COG0210	DNA helicase
AM462_RS10240	COG2885	chlorophyll binding
AM462_RS10245	COG0204	Acyl-transferase
AM462_RS10260	COG2894	cell division
AM462_RS10275	COG1280	lysine exporter protein (LysE YggA)
AM462_RS10280	COG1674	ftsk spoiiie
AM462_RS10280	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AM462_RS10285	COG0492	ferredoxin-NADP+ reductase activity
AM462_RS10290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM462_RS10300	COG0456	acetyltransferase
AM462_RS10345	COG1981	membrane
AM462_RS10360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM462_RS10360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM462_RS10380	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS10390	COG0657	acetylesterase activity
AM462_RS10400	COG0473	3-isopropylmalate dehydrogenase activity
AM462_RS10405	COG0583	DNA-binding transcription factor activity
AM462_RS10425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM462_RS10450	COG0564	pseudouridine synthase activity
AM462_RS10460	COG0358	DNA primase activity
AM462_RS10475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM462_RS10500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM462_RS10530	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM462_RS10540	COG0351	phosphomethylpyrimidine kinase
AM462_RS10540	COG0352	thiamine-phosphate diphosphorylase activity
AM462_RS10540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM462_RS10545	COG1652	LysM domain
AM462_RS10570	COG1399	metal-binding, possibly nucleic acid-binding protein
AM462_RS10575	COG3101	peptidyl-lysine hydroxylation
AM462_RS10580	COG0009	L-threonylcarbamoyladenylate synthase
AM462_RS10585	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM462_RS10590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM462_RS10605	COG4106	trans-aconitate 2-methyltransferase activity
AM462_RS10620	COG2226	methyltransferase
AM462_RS10620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_RS10620	COG0596	Alpha beta hydrolase
AM462_RS10625	COG1877	trehalose-phosphatase activity
AM462_RS10630	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM462_RS10635	COG2223	nitrite transmembrane transporter activity
AM462_RS10655	COG1196	nuclear chromosome segregation
AM462_RS10665	COG0730	response to heat
AM462_RS10680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM462_RS10690	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM462_RS10750	COG0489	protein tyrosine kinase activity
AM462_RS10760	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_RS10760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_RS10790	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM462_RS10795	COG2081	HI0933 family
AM462_RS10805	COG0668	transmembrane transport
AM462_RS10825	COG0583	DNA-binding transcription factor activity
AM462_RS10850	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM462_RS10855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM462_RS10885	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM462_RS10925	COG0745	RESPONSE REGULATOR receiver
AM462_RS10945	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM462_RS10955	COG0384	phenazine biosynthesis protein PhzF
AM462_RS10985	COG1309	transcriptional regulator
AM462_RS10995	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS11010	COG0583	DNA-binding transcription factor activity
AM462_RS11040	COG0583	DNA-binding transcription factor activity
AM462_RS11060	COG0583	DNA-binding transcription factor activity
AM462_RS11065	COG1053	succinate dehydrogenase
AM462_RS11075	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM462_RS11080	COG2814	Major facilitator Superfamily
AM462_RS11085	COG1960	acyl-CoA dehydrogenase activity
AM462_RS11090	COG0583	DNA-binding transcription factor activity
AM462_RS11095	COG1063	alcohol dehydrogenase
AM462_RS11130	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM462_RS11135	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM462_RS11140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM462_RS11155	COG3667	copper resistance
AM462_RS11160	COG2132	Multicopper oxidase
AM462_RS11170	COG0561	phosphatase activity
AM462_RS11175	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM462_RS11185	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM462_RS11200	COG1214	PFAM Peptidase M22, glycoprotease
AM462_RS11250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AM462_RS11260	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM462_RS11265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM462_RS11270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM462_RS11330	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM462_RS11340	COG1846	Transcriptional regulator
AM462_RS11345	COG1764	response to oxidative stress
AM462_RS11385	COG0037	tRNA processing
AM462_RS11395	COG0248	Ppx GppA phosphatase
AM462_RS11425	COG0072	phenylalanine-tRNA ligase activity
AM462_RS11460	COG1238	metal cluster binding
AM462_RS11465	COG0625	glutathione transferase activity
AM462_RS11480	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_RS11485	COG3028	Belongs to the UPF0307 family
AM462_RS11490	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM462_RS11510	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM462_RS11515	COG0617	tRNA 3'-terminal CCA addition
AM462_RS11520	COG1555	photosystem II stabilization
AM462_RS11525	COG3956	TIGRFAM MazG family protein
AM462_RS11535	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM462_RS11555	COG2205	protein histidine kinase activity
AM462_RS11555	COG0784	Response regulator, receiver
AM462_RS11555	COG5002	protein histidine kinase activity
AM462_RS11560	COG1024	Enoyl-CoA hydratase
AM462_RS11565	COG2084	Dehydrogenase
AM462_RS11570	COG3622	Belongs to the hyi family
AM462_RS11600	COG0697	spore germination
AM462_RS11610	COG2814	Major facilitator Superfamily
AM462_RS11630	COG2132	Multicopper oxidase
AM462_RS11645	COG2205	protein histidine kinase activity
AM462_RS11735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM462_RS11745	COG0583	DNA-binding transcription factor activity
AM462_RS11755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM462_RS11765	COG0084	hydrolase, TatD family'
AM462_RS11780	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM462_RS11790	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS11825	COG0440	acetolactate synthase activity
AM462_RS11830	COG0028	Belongs to the TPP enzyme family
AM462_RS11855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS11860	COG0577	efflux transmembrane transporter activity
AM462_RS11860	COG1136	(ABC) transporter
AM462_RS11865	COG1538	Outer membrane efflux protein
AM462_RS11880	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM462_RS11885	COG1162	GTPase activity
AM462_RS11895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM462_RS11935	COG1426	Protein conserved in bacteria
AM462_RS11970	COG0793	Belongs to the peptidase S41A family
AM462_RS11985	COG2267	carboxylic ester hydrolase activity
AM462_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS12000	COG3265	gluconokinase activity
AM462_RS12010	COG0800	Aldolase
AM462_RS12020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM462_RS12025	COG0857	belongs to the CobB CobQ family
AM462_RS12025	COG0280	phosphate acetyltransferase
AM462_RS12030	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM462_RS12030	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM462_RS12050	COG0740	serine-type endopeptidase activity
AM462_RS12060	COG4774	siderophore transport
AM462_RS12070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM462_RS12080	COG2813	Specifically methylates the guanine in position
AM462_RS12080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM462_RS12180	COG0788	formyltetrahydrofolate deformylase activity
AM462_RS12205	COG4651	solute:proton antiporter activity
AM462_RS12205	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_RS12225	COG0724	RNA recognition motif
AM462_RS12230	COG0210	DNA helicase
AM462_RS12255	COG1733	regulation of RNA biosynthetic process
AM462_RS12265	COG2900	Belongs to the SlyX family
AM462_RS12270	COG0488	(ABC) transporter
AM462_RS12275	COG1280	lysine exporter protein (LysE YggA)
AM462_RS12280	COG1560	Kdo2-lipid A biosynthetic process
AM462_RS12290	COG1301	dicarboxylic acid transport
AM462_RS12345	COG0473	3-isopropylmalate dehydrogenase activity
AM462_RS12400	COG0583	DNA-binding transcription factor activity
AM462_RS12410	COG0625	glutathione transferase activity
AM462_RS12415	COG2378	regulation of single-species biofilm formation
AM462_RS12420	COG0546	phosphoglycolate phosphatase activity
AM462_RS12435	COG1530	ribonuclease E activity
AM462_RS12440	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_RS12455	COG0583	DNA-binding transcription factor activity
AM462_RS12460	COG4221	oxidoreductase activity
AM462_RS12465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM462_RS12475	COG0534	Mate efflux family protein
AM462_RS12490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM462_RS12515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM462_RS12515	COG0493	'glutamate synthase
AM462_RS12525	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM462_RS12530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_RS12545	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM462_RS12555	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM462_RS12555	COG0644	oxidoreductase
AM462_RS12565	COG0425	Belongs to the sulfur carrier protein TusA family
AM462_RS12570	COG4535	Mg2 and Co2 transporter CorC
AM462_RS12580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM462_RS12600	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM462_RS12605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM462_RS12605	COG0475	glutathione-regulated potassium exporter activity
AM462_RS12620	COG0484	heat shock protein binding
AM462_RS12625	COG0789	Transcriptional regulator
AM462_RS12630	COG0598	Magnesium transport protein CorA
AM462_RS12645	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM462_RS12650	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM462_RS12655	COG1074	ATP-dependent DNA helicase activity
AM462_RS12660	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM462_RS12680	COG2226	methyltransferase
AM462_RS12695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_RS12700	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM462_RS12715	COG2111	Na H antiporter
AM462_RS12715	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM462_RS12720	COG1006	Multisubunit Na H antiporter MnhC subunit
AM462_RS12725	COG0651	ATP synthesis coupled electron transport
AM462_RS12730	COG1863	multisubunit Na H antiporter MnhE subunit
AM462_RS12735	COG2212	antiporter activity
AM462_RS12740	COG1320	monovalent cation:proton antiporter activity
AM462_RS12755	COG0195	Participates in both transcription termination and antitermination
AM462_RS12805	COG0237	dephospho-CoA kinase activity
AM462_RS12815	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM462_RS12830	COG0497	DNA recombination
AM462_RS12840	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM462_RS12870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM462_RS12870	COG2169	Transcriptional regulator
AM462_RS12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM462_RS12935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AM462_RS12950	COG0326	Molecular chaperone. Has ATPase activity
AM462_RS12965	COG2056	Na+-H+ antiporter family
AM462_RS13065	COG0546	phosphoglycolate phosphatase activity
AM462_RS13070	COG1716	ATPase activity
AM462_RS13115	COG0181	hydroxymethylbilane synthase activity
AM462_RS13125	COG3275	phosphorelay sensor kinase activity
AM462_RS13145	COG1538	Outer membrane efflux protein
AM462_RS13150	COG0697	spore germination
AM462_RS13175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM462_RS13180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM462_RS13185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM462_RS13190	COG0772	Belongs to the SEDS family
AM462_RS13215	COG4974	Belongs to the 'phage' integrase family
AM462_RS13220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_RS13230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM462_RS13240	COG2197	response regulator
AM462_RS13255	COG0793	Belongs to the peptidase S41A family
AM462_RS13260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM462_RS13265	COG0795	lipopolysaccharide-transporting ATPase activity
AM462_RS13305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM462_RS13305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM462_RS13315	COG0004	ammonium transporteR
AM462_RS13320	COG0347	Belongs to the P(II) protein family
AM462_RS13330	COG0606	chelatase, subunit chli
AM462_RS13340	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS13370	COG0789	Transcriptional regulator
AM462_RS13470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_RS13485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM462_RS13500	COG0318	PFAM AMP-dependent synthetase and ligase
AM462_RS13510	COG0477	Major facilitator Superfamily
AM462_RS13515	COG2860	membrane
AM462_RS13520	COG3012	SEC-C Motif Domain Protein
AM462_RS13525	COG1253	flavin adenine dinucleotide binding
AM462_RS13535	COG0477	Major facilitator Superfamily
AM462_RS13545	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM462_RS13590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM462_RS13625	COG1309	transcriptional regulator
AM462_RS13660	COG0758	DNA mediated transformation
AM462_RS13670	COG0697	spore germination
AM462_RS13675	COG1309	transcriptional regulator
AM462_RS13690	COG0386	Belongs to the glutathione peroxidase family
AM462_RS13755	COG1121	(ABC) transporter
AM462_RS13760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM462_RS13765	COG1280	lysine exporter protein (LysE YggA)
AM462_RS13770	COG2837	iron assimilation
AM462_RS13775	COG0281	malic enzyme
AM462_RS13820	COG0519	Catalyzes the synthesis of GMP from XMP
AM462_RS13820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM462_RS13825	COG4399	Belongs to the UPF0754 family
AM462_RS13830	COG2259	Doxx family
AM462_RS13835	COG0586	Pfam SNARE associated Golgi protein
AM462_RS13850	COG1192	Involved in chromosome partitioning
AM462_RS13860	COG0271	Belongs to the BolA IbaG family
AM462_RS13895	COG3756	Protein conserved in bacteria
AM462_RS13990	COG0642	Histidine kinase
AM462_RS13995	COG0745	RESPONSE REGULATOR receiver
AM462_RS14000	COG2194	sulfuric ester hydrolase activity
AM462_RS14010	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM462_RS14015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM462_RS14030	COG1570	exodeoxyribonuclease VII activity
AM462_RS14055	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM462_RS14060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AM462_RS14070	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS14090	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_RS14125	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS14155	COG1324	tolerance protein
AM462_RS14160	COG0673	inositol 2-dehydrogenase activity
AM462_RS14180	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS14230	COG2267	carboxylic ester hydrolase activity
AM462_RS14250	COG3321	synthase
AM462_RS14250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM462_RS14250	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM462_RS14250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM462_RS14255	COG1960	acyl-CoA dehydrogenase activity
AM462_RS14265	COG2197	response regulator
AM462_RS14275	COG3916	Acyl-homoserine-lactone synthase
AM462_RS14280	COG0477	Major facilitator Superfamily
AM462_RS14285	COG1024	Enoyl-CoA hydratase
AM462_RS14290	COG1024	Enoyl-CoA hydratase
AM462_RS14295	COG1960	acyl-CoA dehydrogenase activity
AM462_RS14300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_RS14320	COG1113	amino acid transport
AM462_RS14325	COG1113	amino acid transport
AM462_RS14330	COG0251	oxidation-reduction process
AM462_RS14370	COG0564	pseudouridine synthase activity
AM462_RS14420	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM462_RS14435	COG1802	Transcriptional regulator
AM462_RS14440	COG1448	Aminotransferase
AM462_RS14445	COG0277	FAD linked oxidase domain protein
AM462_RS14455	COG2186	Transcriptional regulator
AM462_RS14465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_RS14480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM462_RS14490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AM462_RS14500	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM462_RS14505	COG0438	transferase activity, transferring glycosyl groups
AM462_RS14515	COG0438	transferase activity, transferring glycosyl groups
AM462_RS14535	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM462_RS14565	COG0728	peptidoglycan biosynthetic process
AM462_RS14570	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM462_RS14630	COG0546	phosphoglycolate phosphatase activity
AM462_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS14655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_RS14660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM462_RS14665	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM462_RS14670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM462_RS14675	COG1116	anion transmembrane transporter activity
AM462_RS14680	COG1309	transcriptional regulator
AM462_RS14685	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM462_RS14695	COG0196	riboflavin kinase activity
AM462_RS14700	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM462_RS14710	COG1047	Peptidyl-prolyl cis-trans
AM462_RS14750	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM462_RS14755	COG0657	acetylesterase activity
AM462_RS14805	COG2951	lytic endotransglycosylase activity
AM462_RS14810	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM462_RS14830	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM462_RS14840	COG0671	phosphoesterase, PA-phosphatase related
AM462_RS14845	COG0861	Integral membrane protein TerC family
AM462_RS14855	COG0754	glutathionylspermidine amidase activity
AM462_RS14865	COG0402	S-adenosylhomocysteine deaminase activity
AM462_RS14880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_RS14885	COG1230	cation diffusion facilitator family transporter
AM462_RS14900	COG0706	membrane insertase activity
AM462_RS14925	COG0592	DNA-directed DNA polymerase activity
AM462_RS14935	COG0187	DNA topoisomerase II activity
AM462_RS14945	COG0586	Pfam SNARE associated Golgi protein
AM462_RS14950	COG0488	(ABC) transporter
AM462_RS14975	COG0596	Alpha beta hydrolase
AM462_RS14980	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM462_RS14985	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM462_RS15030	COG0733	neurotransmitter:sodium symporter activity
AM462_RS15065	COG0583	DNA-binding transcription factor activity
AM462_RS15070	COG2233	PERMEase
AM462_RS15085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS15120	COG2814	Major facilitator Superfamily
AM462_RS15125	COG0656	L-ascorbic acid biosynthetic process
AM462_RS15130	COG0583	DNA-binding transcription factor activity
AM462_RS15145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM462_RS15150	COG1064	alcohol dehydrogenase
AM462_RS15155	COG2818	Glycosylase
AM462_RS15170	COG1194	a g-specific adenine glycosylase
AM462_RS15190	COG2983	Belongs to the UPF0260 family
AM462_RS15195	COG2133	pyrroloquinoline quinone binding
AM462_RS15200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM462_RS15205	COG2116	formate transmembrane transporter activity
AM462_RS15225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM462_RS15230	COG1335	isochorismatase
AM462_RS15235	COG0385	Bile acid
AM462_RS15240	COG0534	Mate efflux family protein
AM462_RS15245	COG1683	Conserved Protein
AM462_RS15265	COG0625	glutathione transferase activity
AM462_RS15275	COG1113	amino acid transport
AM462_RS15285	COG0523	cobalamin synthesis protein
AM462_RS15295	COG2188	Transcriptional regulator
AM462_RS15325	COG0010	Belongs to the arginase family
AM462_RS15340	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM462_RS15380	COG0589	response to stress
AM462_RS15385	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS15415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM462_RS15470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_RS15535	COG3173	Aminoglycoside phosphotransferase
AM462_RS15540	COG0488	(ABC) transporter
AM462_RS15555	COG0482	sulfurtransferase activity
AM462_RS15710	COG1192	Involved in chromosome partitioning
AM462_RS15730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM462_RS15835	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM462_RS15845	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM462_RS15850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM462_RS15940	COG0534	Mate efflux family protein
AM462_RS15945	COG0436	Aminotransferase
AM462_RS15950	COG2733	membrane
AM462_RS15965	COG2918	glutathione biosynthetic process
AM462_RS15980	COG1388	LysM domain
AM462_RS15980	COG5632	N-Acetylmuramoyl-L-alanine amidase
AM462_RS15980	COG3409	Peptidoglycan-binding domain 1 protein
AM462_RS16010	COG3150	esterase
AM462_RS16020	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM462_RS16030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM462_RS16040	COG2233	PERMEase
AM462_RS16045	COG2351	hydroxyisourate hydrolase activity
AM462_RS16080	COG3706	GGDEF domain
AM462_RS16095	COG1393	Belongs to the ArsC family
AM462_RS16100	COG0708	Exodeoxyribonuclease III
AM462_RS16120	COG0189	ligase activity
AM462_RS16140	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM462_RS16150	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM462_RS16165	COG4942	peptidase
AM462_RS16175	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM462_RS16185	COG2119	membrane
AM462_RS16190	COG4774	siderophore transport
AM462_RS16195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM462_RS16195	COG0426	domain, Protein
AM462_RS16220	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM462_RS16240	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS16245	COG1519	Transferase
AM462_RS16250	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM462_RS16255	COG0668	transmembrane transport
AM462_RS16265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM462_RS16270	COG1335	isochorismatase
AM462_RS16275	COG1522	sequence-specific DNA binding
AM462_RS16300	COG2205	protein histidine kinase activity
AM462_RS16300	COG0784	Response regulator, receiver
AM462_RS16300	COG2198	Histidine kinase
AM462_RS16305	COG3162	membrane
AM462_RS16310	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM462_RS16320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM462_RS16335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM462_RS16340	COG1309	transcriptional regulator
AM462_RS16360	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM462_RS16360	COG0352	thiamine-phosphate diphosphorylase activity
AM462_RS16360	COG0351	phosphomethylpyrimidine kinase
AM462_RS16370	COG2814	Major facilitator Superfamily
AM462_RS16385	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM462_RS16395	COG1113	amino acid transport
AM462_RS16405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM462_RS16410	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS16420	COG1335	isochorismatase
AM462_RS16450	COG2814	Major facilitator Superfamily
AM462_RS16455	COG0583	DNA-binding transcription factor activity
AM462_RS16475	COG0667	Aldo Keto reductase
AM462_RS16500	COG1733	regulation of RNA biosynthetic process
AM462_RS16515	COG1733	regulation of RNA biosynthetic process
AM462_RS16525	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_RS16535	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AM462_RS16595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM462_RS16635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM462_RS16665	COG0427	acetyl-CoA hydrolase
AM462_RS16690	COG0659	secondary active sulfate transmembrane transporter activity
AM462_RS16695	COG4221	oxidoreductase activity
AM462_RS16700	COG2873	o-acetylhomoserine
AM462_RS16705	COG0488	(ABC) transporter
AM462_RS16770	COG0833	amino acid
AM462_RS16815	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM462_RS16820	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM462_RS16835	COG2226	methyltransferase
AM462_RS16885	COG0069	glutamate synthase activity
AM462_RS16885	COG0067	glutamate synthase
AM462_RS16885	COG0070	glutamate synthase
AM462_RS16890	COG0493	'glutamate synthase
AM462_RS16900	COG1704	LemA family
AM462_RS16905	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM462_RS16920	COG3307	-O-antigen
AM462_RS16940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM462_RS16955	COG0194	GDP metabolic process
AM462_RS17005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM462_RS17025	COG5380	lipid catabolic process
AM462_RS17030	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM462_RS17055	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM462_RS17060	COG0277	FAD linked oxidase domain protein
AM462_RS17070	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM462_RS17075	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_RS17090	COG1289	transmembrane transporter activity
AM462_RS17100	COG0628	permease
AM462_RS17105	COG1192	Involved in chromosome partitioning
AM462_RS17135	COG0833	amino acid
AM462_RS17140	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM462_RS17145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM462_RS17155	COG1012	belongs to the aldehyde dehydrogenase family
AM462_RS17195	COG0583	DNA-binding transcription factor activity
AM462_RS17245	COG0517	IMP dehydrogenase activity
AM462_RS17250	COG1983	PspC domain protein
AM462_RS17270	COG1960	acyl-CoA dehydrogenase activity
AM462_RS17285	COG0408	coproporphyrinogen oxidase activity
AM462_RS17305	COG0513	Belongs to the DEAD box helicase family
AM462_RS17310	COG1127	ABC transporter
AM462_RS17315	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM462_RS17325	COG2854	intermembrane phospholipid transfer
AM462_RS17335	COG0598	Magnesium transport protein CorA
AM462_RS17345	COG0494	nUDIX hydrolase
AM462_RS17350	COG1040	competence protein
AM462_RS17355	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM462_RS17375	COG1946	Acyl-CoA thioesterase
AM462_RS17380	COG1301	dicarboxylic acid transport
AM462_RS17395	COG1959	2 iron, 2 sulfur cluster binding
AM462_RS17400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM462_RS17400	COG1017	nitric oxide dioxygenase activity
AM462_RS17405	COG0433	COG0433 Predicted ATPase
AM462_RS17410	COG0626	cystathionine gamma-synthase activity
AM462_RS17565	COG1960	acyl-CoA dehydrogenase activity
AM462_RS17570	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM462_RS17600	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM462_RS17605	COG0339	signal peptide processing
AM462_RS17610	COG0557	exoribonuclease II activity
AM462_RS17655	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM462_RS17660	COG2169	Transcriptional regulator
AM462_RS17665	COG0697	spore germination
AM462_RS17670	COG1295	ribonuclease BN
AM462_RS17705	COG1702	phosphate starvation-inducible protein PhoH
AM462_RS17715	COG1196	nuclear chromosome segregation
AM462_RS17715	COG0741	lytic transglycosylase activity
AM462_RS17715	COG0739	heme binding
AM462_RS17745	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM462_RS17750	COG1183	phosphatidylcholine synthase activity
AM462_RS17795	COG1960	acyl-CoA dehydrogenase activity
AM462_RS17800	COG1309	transcriptional regulator
AM462_RS17815	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM462_RS17820	COG1960	acyl-CoA dehydrogenase activity
AM462_RS17840	COG2969	positive regulation of protein catabolic process
AM462_RS17850	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM462_RS17865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM462_RS17870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM462_RS17890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM462_RS17900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM462_RS17905	COG1408	metallophosphoesterase
AM462_RS17915	COG2199	diguanylate cyclase activity
AM462_RS17975	COG1607	acyl-coa hydrolase
AM462_RS18005	COG2350	Protein conserved in bacteria
AM462_RS18015	COG0613	PHP domain protein
AM462_RS18020	COG3781	membrane
AM462_RS18030	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM462_RS18045	COG1862	Preprotein translocase
AM462_RS18075	COG2205	protein histidine kinase activity
AM462_RS18080	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM462_RS18100	COG0726	polysaccharide deacetylase
AM462_RS18105	COG0463	Glycosyl transferase, family 2
AM462_RS18110	COG0438	transferase activity, transferring glycosyl groups
AM462_RS18175	COG1960	acyl-CoA dehydrogenase activity
AM462_RS18180	COG1960	acyl-CoA dehydrogenase activity
AM462_RS18190	COG2205	protein histidine kinase activity
AM462_RS18195	COG0745	RESPONSE REGULATOR receiver
AM462_RS18200	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM462_RS18220	COG2096	Adenosyltransferase
AM462_RS18270	COG0285	dihydrofolate synthase activity
AM462_RS18290	COG0450	alkyl hydroperoxide reductase
AM462_RS18305	COG0477	Major facilitator Superfamily
AM462_RS18310	COG1272	protein, Hemolysin III
AM462_RS18320	COG2153	protein acetylation
AM462_RS18340	COG0183	Belongs to the thiolase family
AM462_RS18345	COG2207	Transcriptional regulator
AM462_RS18365	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM462_RS18395	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM462_RS18395	COG2885	chlorophyll binding
AM462_RS18400	COG1690	Belongs to the RtcB family
AM462_RS18405	COG0833	amino acid
AM462_RS18415	COG2233	PERMEase
AM462_RS18420	COG1217	gtp-binding protein TYPA
AM462_RS18445	COG2094	Belongs to the DNA glycosylase MPG family
AM462_RS18450	COG4772	TonB-dependent receptor
AM462_RS18455	COG1902	pentaerythritol trinitrate reductase activity
AM462_RS18460	COG0679	Auxin Efflux Carrier
AM462_RS18470	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM462_RS18475	COG0354	folic acid binding
AM462_RS18485	COG3189	MarR family transcriptional regulator
AM462_RS18490	COG2824	Alkylphosphonate utilization operon protein PhnA
AM462_RS18495	COG3422	double-strand break repair
AM462_RS18535	COG0840	transmembrane signaling receptor activity
AM462_RS18550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM462_RS18560	COG2826	transposase and inactivated derivatives, IS30 family
AM462_RS18575	COG5510	response to toxic substance
AM462_RS18585	COG2832	Protein of unknown function (DUF454)
AM462_RS18590	COG1376	ErfK ybiS ycfS ynhG family protein
AM462_RS18630	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM462_RS18640	COG1289	transmembrane transporter activity
AM462_RS18645	COG2814	Major facilitator Superfamily
AM462_RS18665	COG1115	amino acid carrier protein
AM462_RS18670	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM462_RS18675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM462_RS18680	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM462_RS18705	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM462_RS18715	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM462_RS18720	COG1077	Cell shape determining protein MreB Mrl
AM462_RS18725	COG1792	Involved in formation and maintenance of cell shape
AM462_RS18730	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM462_RS18735	COG0424	maF-like protein
AM462_RS18740	COG1530	ribonuclease E activity
AM462_RS18750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_RS18760	COG0560	Phosphoserine phosphatase
AM462_RS18770	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM462_RS18795	COG2207	Transcriptional regulator
AM462_RS18850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM462_RS18855	COG4197	protein conserved in bacteria, prophage-related
AM462_RS18885	COG0305	Participates in initiation and elongation during chromosome replication
AM462_RS18910	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AM462_RS18965	COG4626	Terminase
AM462_RS18965	COG1802	Transcriptional regulator
AM462_RS18970	COG4695	Portal protein
AM462_RS18975	COG0740	serine-type endopeptidase activity
AM462_RS19030	COG0741	lytic transglycosylase activity
AM462_RS19030	COG1196	nuclear chromosome segregation
AM462_RS19030	COG0739	heme binding
AM462_RS19090	COG1113	amino acid transport
AM462_RS19095	COG2828	Protein conserved in bacteria
AM462_RS19100	COG0142	geranyltranstransferase activity
AM462_RS19105	COG2315	Protein conserved in bacteria
AM462_RS19120	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM462_RS19140	COG2194	sulfuric ester hydrolase activity
AM462_RS19145	COG0745	RESPONSE REGULATOR receiver
AM462_RS19150	COG0642	Histidine kinase
AM462_RS19160	COG0004	ammonium transporteR
AM462_RS19170	COG0583	DNA-binding transcription factor activity
AM462_RS19190	COG0525	valine-tRNA ligase activity
AM462_RS19200	COG1028	Short-chain dehydrogenase reductase Sdr
AM462_RS19210	COG0393	Putative heavy-metal-binding
AM462_RS19215	COG0393	Putative heavy-metal-binding
AM462_RS19220	COG1538	Outer membrane efflux protein
AM462_RS19230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS19235	COG0671	phosphoesterase, PA-phosphatase related
AM462_RS19265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM462_RS19280	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM462_RS19280	COG1648	precorrin-2 dehydrogenase activity
AM462_RS19285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM462_RS19290	COG1733	regulation of RNA biosynthetic process
AM462_RS19300	COG0531	amino acid
AM462_RS19315	COG0321	lipoyl(octanoyl) transferase activity
AM462_RS19320	COG2921	Belongs to the UPF0250 family
AM462_RS19355	COG2009	succinate dehydrogenase
AM462_RS19360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM462_RS19365	COG1053	succinate dehydrogenase
AM462_RS19370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM462_RS19395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM462_RS19425	COG2354	Protein conserved in bacteria
AM462_RS19430	COG2321	neutral zinc metallopeptidase
AM462_RS19450	COG2843	Capsule synthesis protein
AM462_RS19465	COG0589	response to stress
AM462_RS19485	COG0505	Belongs to the CarA family
AM462_RS19510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM462_RS19515	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM462_RS19565	COG0477	Major facilitator Superfamily
AM462_RS19570	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM462_RS19585	COG1597	lipid kinase activity
AM462_RS19590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM462_RS19615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM462_RS19620	COG0584	glycerophosphoryl diester phosphodiesterase
AM462_RS19640	COG0741	lytic transglycosylase activity
AM462_RS19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM462_RS19680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM462_RS19720	COG0778	Nitroreductase
AM462_RS19735	COG1929	Belongs to the glycerate kinase type-1 family
AM462_RS19740	COG0243	molybdopterin cofactor binding
AM462_RS19745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM462_RS19750	COG3339	Conserved Protein
AM462_RS19760	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM462_RS19775	COG1113	amino acid transport
AM462_RS19785	COG0019	diaminopimelate decarboxylase activity
AM462_RS19795	COG2267	carboxylic ester hydrolase activity
AM462_RS19800	COG1280	lysine exporter protein (LysE YggA)
AM462_RS19805	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM462_RS19835	COG0463	Glycosyl transferase, family 2
AM462_RS19855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM462_RS19890	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM462_RS19895	COG1136	(ABC) transporter
AM462_RS19900	COG2333	competence protein COMEC
AM462_RS19900	COG0658	competence protein
AM462_RS19910	COG0616	signal peptide processing
AM462_RS19910	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM462_RS19915	COG0596	Alpha beta hydrolase
AM462_RS19920	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM462_RS19930	COG0628	permease
AM462_RS19970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM462_RS19990	COG0823	Involved in the tonB-independent uptake of proteins
AM462_RS20010	COG0824	Thioesterase
AM462_RS20015	COG1473	amidohydrolase
AM462_RS20035	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM462_RS20035	COG0047	phosphoribosylformylglycinamidine synthase activity
AM462_RS20040	COG2814	Major facilitator Superfamily
AM462_RS20050	COG1024	Enoyl-CoA hydratase
AM462_RS20055	COG1056	cytidyltransferase-related domain
AM462_RS20055	COG1051	belongs to the nudix hydrolase family
AM462_RS20065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM462_RS20080	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM462_RS20095	COG4625	pathogenesis
AM462_RS20100	COG0583	DNA-binding transcription factor activity
AM462_RS20105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM462_RS20110	COG4208	sulfate ABC transporter
AM462_RS20115	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM462_RS20125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM462_RS20130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM462_RS20135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM462_RS20155	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM462_RS20170	COG0681	Belongs to the peptidase S26 family
AM462_RS20185	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM462_RS20195	COG1381	Involved in DNA repair and RecF pathway recombination
AM462_RS20200	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM462_RS20210	COG4221	oxidoreductase activity
AM462_RS20240	COG0436	Aminotransferase
AM462_RS20260	COG0556	nucleotide-excision repair