locus-tag	class	description
AM480_RS00110	COG1724	mRNA binding
AM480_RS00115	COG1598	PFAM Uncharacterised protein family UPF0150
AM480_RS00170	COG0740	serine-type endopeptidase activity
AM480_RS00180	COG4695	Portal protein
AM480_RS00390	COG1131	(ABC) transporter
AM480_RS00395	COG0842	Transport permease protein
AM480_RS00410	COG0772	Belongs to the SEDS family
AM480_RS00415	COG2951	lytic endotransglycosylase activity
AM480_RS00440	COG2207	Transcriptional regulator
AM480_RS00455	COG0052	Belongs to the universal ribosomal protein uS2 family
AM480_RS00460	COG0024	Methionine aminopeptidase
AM480_RS00470	COG2223	nitrite transmembrane transporter activity
AM480_RS00480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM480_RS00485	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM480_RS00490	COG1960	acyl-CoA dehydrogenase activity
AM480_RS00505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AM480_RS00510	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AM480_RS00515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM480_RS00535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM480_RS00540	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AM480_RS00545	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AM480_RS00580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AM480_RS00590	COG0174	glutamine synthetase
AM480_RS00605	COG0512	Glutamine amidotransferase of anthranilate synthase
AM480_RS00645	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AM480_RS00655	COG0302	gtp cyclohydrolase
AM480_RS00680	COG3739	integral membrane protein
AM480_RS00695	COG1169	isochorismate synthase
AM480_RS00705	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AM480_RS00710	COG1132	(ABC) transporter
AM480_RS00715	COG1132	(ABC) transporter
AM480_RS00730	COG1535	isochorismatase
AM480_RS00730	COG3433	isochorismatase activity
AM480_RS00735	COG1021	2,3-dihydroxybenzoate-AMP ligase
AM480_RS00740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM480_RS00750	COG4774	siderophore transport
AM480_RS00755	COG4607	ABC-type enterochelin transport system periplasmic component
AM480_RS00760	COG4604	ABC transporter, ATP-binding protein
AM480_RS00765	COG4605	iron ion homeostasis
AM480_RS00770	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM480_RS00775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM480_RS00790	COG2964	Protein conserved in bacteria
AM480_RS00800	COG1741	Belongs to the pirin family
AM480_RS00825	COG2879	small protein
AM480_RS00830	COG1966	Carbon starvation protein
AM480_RS00850	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AM480_RS00870	COG2211	Major facilitator Superfamily
AM480_RS00875	COG1067	ATP-dependent peptidase activity
AM480_RS00880	COG0583	DNA-binding transcription factor activity
AM480_RS00905	COG1686	Belongs to the peptidase S11 family
AM480_RS00910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AM480_RS00950	COG0616	signal peptide processing
AM480_RS00955	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AM480_RS00965	COG0573	inorganic phosphate transmembrane transporter activity
AM480_RS00970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AM480_RS00975	COG1113	amino acid transport
AM480_RS00980	COG3961	Belongs to the TPP enzyme family
AM480_RS00985	COG1522	sequence-specific DNA binding
AM480_RS00995	COG0076	glutamate decarboxylase activity
AM480_RS01000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM480_RS01010	COG1309	transcriptional regulator
AM480_RS01025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM480_RS01060	COG0352	thiamine-phosphate diphosphorylase activity
AM480_RS01085	COG0612	Peptidase, M16
AM480_RS01095	COG1823	symporter activity
AM480_RS01100	COG0583	DNA-binding transcription factor activity
AM480_RS01105	COG0477	Major facilitator Superfamily
AM480_RS01130	COG1187	pseudouridine synthase activity
AM480_RS01145	COG1686	Belongs to the peptidase S11 family
AM480_RS01150	COG1252	NADH dehydrogenase
AM480_RS01160	COG0415	Belongs to the DNA photolyase family
AM480_RS01175	COG1215	transferase activity, transferring glycosyl groups
AM480_RS01205	COG2070	2-Nitropropane dioxygenase
AM480_RS01260	COG0556	nucleotide-excision repair
AM480_RS01280	COG0436	Aminotransferase
AM480_RS01310	COG4221	oxidoreductase activity
AM480_RS01320	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AM480_RS01325	COG1381	Involved in DNA repair and RecF pathway recombination
AM480_RS01335	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AM480_RS01350	COG0681	Belongs to the peptidase S26 family
AM480_RS01365	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AM480_RS01385	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AM480_RS01390	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AM480_RS01395	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AM480_RS01405	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AM480_RS01410	COG4208	sulfate ABC transporter
AM480_RS01415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AM480_RS01420	COG0583	DNA-binding transcription factor activity
AM480_RS01425	COG4625	pathogenesis
AM480_RS01440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AM480_RS01455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AM480_RS01465	COG1056	cytidyltransferase-related domain
AM480_RS01465	COG1051	belongs to the nudix hydrolase family
AM480_RS01470	COG1024	Enoyl-CoA hydratase
AM480_RS01480	COG2814	Major facilitator Superfamily
AM480_RS01485	COG0047	phosphoribosylformylglycinamidine synthase activity
AM480_RS01485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AM480_RS01505	COG1473	amidohydrolase
AM480_RS01510	COG0824	Thioesterase
AM480_RS01530	COG0823	Involved in the tonB-independent uptake of proteins
AM480_RS01550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM480_RS01585	COG0628	permease
AM480_RS01595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AM480_RS01600	COG0596	Alpha beta hydrolase
AM480_RS01605	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AM480_RS01605	COG0616	signal peptide processing
AM480_RS01615	COG2333	competence protein COMEC
AM480_RS01615	COG0658	competence protein
AM480_RS01620	COG1136	(ABC) transporter
AM480_RS01625	COG4591	ABC-type transport system involved in lipoprotein release permease component
AM480_RS01655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM480_RS01675	COG0463	Glycosyl transferase, family 2
AM480_RS01705	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AM480_RS01710	COG1280	lysine exporter protein (LysE YggA)
AM480_RS01720	COG0019	diaminopimelate decarboxylase activity
AM480_RS01730	COG1113	amino acid transport
AM480_RS01745	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AM480_RS01755	COG3339	Conserved Protein
AM480_RS01760	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AM480_RS01765	COG0243	molybdopterin cofactor binding
AM480_RS01770	COG1929	Belongs to the glycerate kinase type-1 family
AM480_RS01785	COG0778	Nitroreductase
AM480_RS01835	COG3811	Belongs to the UPF0386 family
AM480_RS01845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM480_RS01860	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AM480_RS01885	COG0741	lytic transglycosylase activity
AM480_RS01905	COG0584	glycerophosphoryl diester phosphodiesterase
AM480_RS01935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM480_RS01940	COG1597	lipid kinase activity
AM480_RS01955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AM480_RS01960	COG0477	Major facilitator Superfamily
AM480_RS02010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AM480_RS02015	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM480_RS02040	COG0505	Belongs to the CarA family
AM480_RS02060	COG0589	response to stress
AM480_RS02075	COG2843	Capsule synthesis protein
AM480_RS02095	COG2321	neutral zinc metallopeptidase
AM480_RS02100	COG2354	Protein conserved in bacteria
AM480_RS02120	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM480_RS02145	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AM480_RS02150	COG1053	succinate dehydrogenase
AM480_RS02155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AM480_RS02195	COG2921	Belongs to the UPF0250 family
AM480_RS02200	COG0321	lipoyl(octanoyl) transferase activity
AM480_RS02215	COG0531	amino acid
AM480_RS02225	COG1733	regulation of RNA biosynthetic process
AM480_RS02230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AM480_RS02235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AM480_RS02235	COG1648	precorrin-2 dehydrogenase activity
AM480_RS02250	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AM480_RS02275	COG0215	cysteine-tRNA ligase activity
AM480_RS02280	COG0671	phosphoesterase, PA-phosphatase related
AM480_RS02285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM480_RS02295	COG1538	Outer membrane efflux protein
AM480_RS02300	COG0393	Putative heavy-metal-binding
AM480_RS02305	COG0393	Putative heavy-metal-binding
AM480_RS02315	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS02325	COG0525	valine-tRNA ligase activity
AM480_RS02345	COG0583	DNA-binding transcription factor activity
AM480_RS02355	COG0004	ammonium transporteR
AM480_RS02365	COG0642	Histidine kinase
AM480_RS02370	COG0745	RESPONSE REGULATOR receiver
AM480_RS02375	COG2194	sulfuric ester hydrolase activity
AM480_RS02395	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM480_RS02410	COG2315	Protein conserved in bacteria
AM480_RS02415	COG0142	geranyltranstransferase activity
AM480_RS02420	COG2828	Protein conserved in bacteria
AM480_RS02425	COG1113	amino acid transport
AM480_RS02435	COG0582	viral genome integration into host DNA
AM480_RS02615	COG0305	Participates in initiation and elongation during chromosome replication
AM480_RS02640	COG3620	sequence-specific DNA binding
AM480_RS02700	COG2207	Transcriptional regulator
AM480_RS02725	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM480_RS02735	COG0560	Phosphoserine phosphatase
AM480_RS02745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AM480_RS02755	COG1530	ribonuclease E activity
AM480_RS02760	COG0424	maF-like protein
AM480_RS02765	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AM480_RS02770	COG1792	Involved in formation and maintenance of cell shape
AM480_RS02775	COG1077	Cell shape determining protein MreB Mrl
AM480_RS02780	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM480_RS02790	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AM480_RS02815	COG3590	peptidase
AM480_RS02820	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AM480_RS02825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM480_RS02830	COG1752	Esterase of the alpha-beta hydrolase superfamily
AM480_RS02835	COG1115	amino acid carrier protein
AM480_RS02855	COG2814	Major facilitator Superfamily
AM480_RS02860	COG1289	transmembrane transporter activity
AM480_RS02870	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AM480_RS02910	COG1376	ErfK ybiS ycfS ynhG family protein
AM480_RS02915	COG2832	Protein of unknown function (DUF454)
AM480_RS02925	COG5510	response to toxic substance
AM480_RS02945	COG0840	transmembrane signaling receptor activity
AM480_RS02985	COG3422	double-strand break repair
AM480_RS02990	COG2824	Alkylphosphonate utilization operon protein PhnA
AM480_RS02995	COG3189	MarR family transcriptional regulator
AM480_RS03005	COG0354	folic acid binding
AM480_RS03010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM480_RS03020	COG0679	Auxin Efflux Carrier
AM480_RS03025	COG1902	pentaerythritol trinitrate reductase activity
AM480_RS03030	COG4772	TonB-dependent receptor
AM480_RS03035	COG2094	Belongs to the DNA glycosylase MPG family
AM480_RS03060	COG1217	gtp-binding protein TYPA
AM480_RS03065	COG2233	PERMEase
AM480_RS03075	COG0833	amino acid
AM480_RS03080	COG1690	Belongs to the RtcB family
AM480_RS03085	COG2885	chlorophyll binding
AM480_RS03085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AM480_RS03095	COG0183	Belongs to the thiolase family
AM480_RS03115	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM480_RS03135	COG2207	Transcriptional regulator
AM480_RS03140	COG0183	Belongs to the thiolase family
AM480_RS03170	COG1272	protein, Hemolysin III
AM480_RS03175	COG0477	Major facilitator Superfamily
AM480_RS03190	COG0450	alkyl hydroperoxide reductase
AM480_RS03210	COG0285	dihydrofolate synthase activity
AM480_RS03255	COG4206	TonB-dependent receptor
AM480_RS03260	COG2096	Adenosyltransferase
AM480_RS03265	COG0584	glycerophosphoryl diester phosphodiesterase
AM480_RS03280	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AM480_RS03285	COG0745	RESPONSE REGULATOR receiver
AM480_RS03290	COG2205	protein histidine kinase activity
AM480_RS03300	COG1960	acyl-CoA dehydrogenase activity
AM480_RS03305	COG1960	acyl-CoA dehydrogenase activity
AM480_RS03390	COG0438	transferase activity, transferring glycosyl groups
AM480_RS03395	COG0463	Glycosyl transferase, family 2
AM480_RS03400	COG0726	polysaccharide deacetylase
AM480_RS03420	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AM480_RS03480	COG1862	Preprotein translocase
AM480_RS03490	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AM480_RS03495	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AM480_RS03505	COG3781	membrane
AM480_RS03510	COG0613	PHP domain protein
AM480_RS03520	COG2350	Protein conserved in bacteria
AM480_RS03550	COG1607	acyl-coa hydrolase
AM480_RS03610	COG2199	diguanylate cyclase activity
AM480_RS03620	COG1408	metallophosphoesterase
AM480_RS03625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM480_RS03635	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AM480_RS03655	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AM480_RS03660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AM480_RS03675	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AM480_RS03685	COG2969	positive regulation of protein catabolic process
AM480_RS03705	COG1960	acyl-CoA dehydrogenase activity
AM480_RS03710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM480_RS03725	COG1309	transcriptional regulator
AM480_RS03730	COG1960	acyl-CoA dehydrogenase activity
AM480_RS03780	COG1183	phosphatidylcholine synthase activity
AM480_RS03785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AM480_RS03815	COG1196	nuclear chromosome segregation
AM480_RS03815	COG0741	lytic transglycosylase activity
AM480_RS03815	COG0739	heme binding
AM480_RS03825	COG1702	phosphate starvation-inducible protein PhoH
AM480_RS03860	COG1295	ribonuclease BN
AM480_RS03865	COG0697	spore germination
AM480_RS03875	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM480_RS03920	COG0557	exoribonuclease II activity
AM480_RS03925	COG0339	signal peptide processing
AM480_RS03930	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AM480_RS03960	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AM480_RS03965	COG1960	acyl-CoA dehydrogenase activity
AM480_RS04120	COG0626	cystathionine gamma-synthase activity
AM480_RS04125	COG0433	COG0433 Predicted ATPase
AM480_RS04135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM480_RS04135	COG1017	nitric oxide dioxygenase activity
AM480_RS04140	COG1959	2 iron, 2 sulfur cluster binding
AM480_RS04155	COG1301	dicarboxylic acid transport
AM480_RS04160	COG1946	Acyl-CoA thioesterase
AM480_RS04180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AM480_RS04185	COG1040	competence protein
AM480_RS04190	COG0494	nUDIX hydrolase
AM480_RS04200	COG0598	Magnesium transport protein CorA
AM480_RS04210	COG2854	intermembrane phospholipid transfer
AM480_RS04220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AM480_RS04225	COG1127	ABC transporter
AM480_RS04230	COG0513	Belongs to the DEAD box helicase family
AM480_RS04250	COG0408	coproporphyrinogen oxidase activity
AM480_RS04265	COG1960	acyl-CoA dehydrogenase activity
AM480_RS04275	COG1983	PspC domain protein
AM480_RS04280	COG0517	IMP dehydrogenase activity
AM480_RS04315	COG1106	Psort location Cytoplasmic, score
AM480_RS04335	COG0583	DNA-binding transcription factor activity
AM480_RS04375	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS04385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM480_RS04390	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM480_RS04395	COG0833	amino acid
AM480_RS04425	COG1192	Involved in chromosome partitioning
AM480_RS04430	COG0628	permease
AM480_RS04440	COG1289	transmembrane transporter activity
AM480_RS04455	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM480_RS04460	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AM480_RS04475	COG0277	FAD linked oxidase domain protein
AM480_RS04480	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AM480_RS04505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AM480_RS04510	COG5380	lipid catabolic process
AM480_RS04530	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AM480_RS04580	COG0194	GDP metabolic process
AM480_RS04595	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM480_RS04615	COG3307	-O-antigen
AM480_RS04630	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AM480_RS04635	COG1704	LemA family
AM480_RS04645	COG0493	'glutamate synthase
AM480_RS04650	COG0067	glutamate synthase
AM480_RS04650	COG0070	glutamate synthase
AM480_RS04650	COG0069	glutamate synthase activity
AM480_RS04700	COG2226	methyltransferase
AM480_RS04715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AM480_RS04720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AM480_RS04765	COG0833	amino acid
AM480_RS04850	COG0488	(ABC) transporter
AM480_RS04855	COG2873	o-acetylhomoserine
AM480_RS04860	COG4221	oxidoreductase activity
AM480_RS04865	COG0659	secondary active sulfate transmembrane transporter activity
AM480_RS04890	COG0427	acetyl-CoA hydrolase
AM480_RS04920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AM480_RS04950	COG2329	Antibiotic biosynthesis monooxygenase
AM480_RS04965	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AM480_RS05035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM480_RS05130	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM480_RS05140	COG1733	regulation of RNA biosynthetic process
AM480_RS05175	COG0667	Aldo Keto reductase
AM480_RS05195	COG0583	DNA-binding transcription factor activity
AM480_RS05200	COG2814	Major facilitator Superfamily
AM480_RS05210	COG1113	amino acid transport
AM480_RS05230	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AM480_RS05230	COG2508	Transcriptional regulator
AM480_RS05260	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS05275	COG1335	isochorismatase
AM480_RS05285	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS05290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AM480_RS05300	COG1113	amino acid transport
AM480_RS05310	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM480_RS05325	COG2814	Major facilitator Superfamily
AM480_RS05335	COG0352	thiamine-phosphate diphosphorylase activity
AM480_RS05335	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM480_RS05335	COG0351	phosphomethylpyrimidine kinase
AM480_RS05355	COG1309	transcriptional regulator
AM480_RS05360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AM480_RS05375	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM480_RS05385	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM480_RS05390	COG3162	membrane
AM480_RS05395	COG2205	protein histidine kinase activity
AM480_RS05395	COG2198	Histidine kinase
AM480_RS05395	COG0784	Response regulator, receiver
AM480_RS05420	COG1522	sequence-specific DNA binding
AM480_RS05425	COG1335	isochorismatase
AM480_RS05430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM480_RS05440	COG0668	transmembrane transport
AM480_RS05445	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AM480_RS05450	COG1519	Transferase
AM480_RS05455	COG1902	pentaerythritol trinitrate reductase activity
AM480_RS05475	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AM480_RS05500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS05500	COG0426	domain, Protein
AM480_RS05505	COG4774	siderophore transport
AM480_RS05510	COG2119	membrane
AM480_RS05520	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM480_RS05530	COG4942	peptidase
AM480_RS05545	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AM480_RS05555	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AM480_RS05575	COG0189	ligase activity
AM480_RS05595	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AM480_RS05610	COG0708	Exodeoxyribonuclease III
AM480_RS05615	COG1393	Belongs to the ArsC family
AM480_RS05630	COG3706	GGDEF domain
AM480_RS05665	COG2351	hydroxyisourate hydrolase activity
AM480_RS05670	COG2233	PERMEase
AM480_RS05680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM480_RS05690	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AM480_RS05700	COG3150	esterase
AM480_RS05750	COG2918	glutathione biosynthetic process
AM480_RS05765	COG2733	membrane
AM480_RS05770	COG0436	Aminotransferase
AM480_RS05775	COG0534	Mate efflux family protein
AM480_RS05865	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AM480_RS05870	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AM480_RS05880	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AM480_RS05885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM480_RS05900	COG0010	Belongs to the arginase family
AM480_RS05930	COG2188	Transcriptional regulator
AM480_RS05940	COG0523	cobalamin synthesis protein
AM480_RS05950	COG1113	amino acid transport
AM480_RS05960	COG0625	glutathione transferase activity
AM480_RS05980	COG1683	Conserved Protein
AM480_RS05985	COG0534	Mate efflux family protein
AM480_RS05990	COG0385	Bile acid
AM480_RS05995	COG1335	isochorismatase
AM480_RS06000	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM480_RS06020	COG2116	formate transmembrane transporter activity
AM480_RS06025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AM480_RS06030	COG2133	pyrroloquinoline quinone binding
AM480_RS06035	COG2983	Belongs to the UPF0260 family
AM480_RS06055	COG1194	a g-specific adenine glycosylase
AM480_RS06070	COG2818	Glycosylase
AM480_RS06075	COG1064	alcohol dehydrogenase
AM480_RS06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM480_RS06095	COG0583	DNA-binding transcription factor activity
AM480_RS06100	COG0656	L-ascorbic acid biosynthetic process
AM480_RS06105	COG2814	Major facilitator Superfamily
AM480_RS06140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM480_RS06155	COG2233	PERMEase
AM480_RS06160	COG0583	DNA-binding transcription factor activity
AM480_RS06195	COG0733	neurotransmitter:sodium symporter activity
AM480_RS06240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM480_RS06245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AM480_RS06250	COG0596	Alpha beta hydrolase
AM480_RS06275	COG0488	(ABC) transporter
AM480_RS06280	COG0586	Pfam SNARE associated Golgi protein
AM480_RS06290	COG0187	DNA topoisomerase II activity
AM480_RS06300	COG0592	DNA-directed DNA polymerase activity
AM480_RS06325	COG0706	membrane insertase activity
AM480_RS06340	COG1230	cation diffusion facilitator family transporter
AM480_RS06360	COG0402	S-adenosylhomocysteine deaminase activity
AM480_RS06370	COG0754	glutathionylspermidine amidase activity
AM480_RS06380	COG0861	Integral membrane protein TerC family
AM480_RS06385	COG0671	phosphoesterase, PA-phosphatase related
AM480_RS06395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AM480_RS06415	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AM480_RS06420	COG2951	lytic endotransglycosylase activity
AM480_RS06470	COG0657	acetylesterase activity
AM480_RS06475	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AM480_RS06515	COG1047	Peptidyl-prolyl cis-trans
AM480_RS06525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AM480_RS06530	COG0196	riboflavin kinase activity
AM480_RS06540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AM480_RS06545	COG1309	transcriptional regulator
AM480_RS06550	COG1116	anion transmembrane transporter activity
AM480_RS06555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM480_RS06560	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM480_RS06565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM480_RS06570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM480_RS06590	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS06595	COG0546	phosphoglycolate phosphatase activity
AM480_RS06655	COG3023	N-Acetylmuramoyl-L-alanine amidase
AM480_RS06660	COG0728	peptidoglycan biosynthetic process
AM480_RS06690	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AM480_RS06700	COG5039	Polysaccharide pyruvyl transferase
AM480_RS06715	COG0438	transferase activity, transferring glycosyl groups
AM480_RS06720	COG1215	transferase activity, transferring glycosyl groups
AM480_RS06730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AM480_RS06735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AM480_RS06750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM480_RS06765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM480_RS06775	COG2186	Transcriptional regulator
AM480_RS06785	COG0277	FAD linked oxidase domain protein
AM480_RS06790	COG1448	Aminotransferase
AM480_RS06800	COG1802	Transcriptional regulator
AM480_RS06815	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AM480_RS06835	COG1051	belongs to the nudix hydrolase family
AM480_RS06875	COG0564	pseudouridine synthase activity
AM480_RS06915	COG0251	oxidation-reduction process
AM480_RS06920	COG1113	amino acid transport
AM480_RS06925	COG1113	amino acid transport
AM480_RS06945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM480_RS06950	COG1960	acyl-CoA dehydrogenase activity
AM480_RS06955	COG1024	Enoyl-CoA hydratase
AM480_RS06960	COG1024	Enoyl-CoA hydratase
AM480_RS06965	COG0477	Major facilitator Superfamily
AM480_RS06970	COG3916	Acyl-homoserine-lactone synthase
AM480_RS06980	COG2197	response regulator
AM480_RS06990	COG1960	acyl-CoA dehydrogenase activity
AM480_RS06995	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AM480_RS06995	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AM480_RS06995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AM480_RS06995	COG3321	synthase
AM480_RS07035	COG0271	Belongs to the BolA IbaG family
AM480_RS07045	COG1192	Involved in chromosome partitioning
AM480_RS07060	COG0586	Pfam SNARE associated Golgi protein
AM480_RS07065	COG2259	Doxx family
AM480_RS07070	COG4399	Belongs to the UPF0754 family
AM480_RS07075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM480_RS07075	COG0519	Catalyzes the synthesis of GMP from XMP
AM480_RS07120	COG0281	malic enzyme
AM480_RS07125	COG2837	iron assimilation
AM480_RS07130	COG1280	lysine exporter protein (LysE YggA)
AM480_RS07135	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AM480_RS07140	COG1121	(ABC) transporter
AM480_RS07205	COG0386	Belongs to the glutathione peroxidase family
AM480_RS07220	COG1309	transcriptional regulator
AM480_RS07225	COG0697	spore germination
AM480_RS07235	COG0758	DNA mediated transformation
AM480_RS07270	COG1309	transcriptional regulator
AM480_RS07305	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AM480_RS07315	COG0655	NAD(P)H dehydrogenase (quinone) activity
AM480_RS07350	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM480_RS07360	COG2814	Major facilitator Superfamily
AM480_RS07370	COG1253	flavin adenine dinucleotide binding
AM480_RS07375	COG3012	SEC-C Motif Domain Protein
AM480_RS07380	COG2860	membrane
AM480_RS07385	COG0477	Major facilitator Superfamily
AM480_RS07395	COG0318	PFAM AMP-dependent synthetase and ligase
AM480_RS07410	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AM480_RS07425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM480_RS07435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM480_RS07440	COG0606	chelatase, subunit chli
AM480_RS07450	COG0347	Belongs to the P(II) protein family
AM480_RS07455	COG0004	ammonium transporteR
AM480_RS07465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM480_RS07465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AM480_RS07505	COG0795	lipopolysaccharide-transporting ATPase activity
AM480_RS07510	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AM480_RS07515	COG0793	Belongs to the peptidase S41A family
AM480_RS07530	COG2197	response regulator
AM480_RS07540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AM480_RS07550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AM480_RS07555	COG4974	Belongs to the 'phage' integrase family
AM480_RS07580	COG0772	Belongs to the SEDS family
AM480_RS07585	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM480_RS07590	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AM480_RS07595	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AM480_RS07630	COG0697	spore germination
AM480_RS07635	COG1538	Outer membrane efflux protein
AM480_RS07655	COG3275	phosphorelay sensor kinase activity
AM480_RS07665	COG0181	hydroxymethylbilane synthase activity
AM480_RS07715	COG1716	ATPase activity
AM480_RS07720	COG0546	phosphoglycolate phosphatase activity
AM480_RS07815	COG0596	Alpha beta hydrolase
AM480_RS07820	COG2056	Na+-H+ antiporter family
AM480_RS07835	COG0326	Molecular chaperone. Has ATPase activity
AM480_RS07850	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AM480_RS07925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AM480_RS07930	COG2169	Transcriptional regulator
AM480_RS07930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM480_RS07960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AM480_RS07970	COG0497	DNA recombination
AM480_RS07985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AM480_RS07995	COG0237	dephospho-CoA kinase activity
AM480_RS08045	COG0195	Participates in both transcription termination and antitermination
AM480_RS08060	COG1320	monovalent cation:proton antiporter activity
AM480_RS08065	COG2212	antiporter activity
AM480_RS08070	COG1863	multisubunit Na H antiporter MnhE subunit
AM480_RS08075	COG0651	ATP synthesis coupled electron transport
AM480_RS08080	COG1006	Multisubunit Na H antiporter MnhC subunit
AM480_RS08085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM480_RS08085	COG2111	Na H antiporter
AM480_RS08100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AM480_RS08110	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM480_RS08120	COG2226	methyltransferase
AM480_RS08140	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AM480_RS08145	COG1074	ATP-dependent DNA helicase activity
AM480_RS08150	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM480_RS08155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM480_RS08170	COG0598	Magnesium transport protein CorA
AM480_RS08175	COG0789	Transcriptional regulator
AM480_RS08180	COG0484	heat shock protein binding
AM480_RS08195	COG0475	glutathione-regulated potassium exporter activity
AM480_RS08195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM480_RS08200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AM480_RS08220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM480_RS08230	COG4535	Mg2 and Co2 transporter CorC
AM480_RS08235	COG0425	Belongs to the sulfur carrier protein TusA family
AM480_RS08240	COG0644	oxidoreductase
AM480_RS08240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AM480_RS08250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AM480_RS08265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM480_RS08270	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AM480_RS08280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM480_RS08280	COG0493	'glutamate synthase
AM480_RS08310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AM480_RS08325	COG0534	Mate efflux family protein
AM480_RS08335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AM480_RS08340	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS08345	COG0583	DNA-binding transcription factor activity
AM480_RS08360	COG0318	PFAM AMP-dependent synthetase and ligase
AM480_RS08365	COG1530	ribonuclease E activity
AM480_RS08380	COG0546	phosphoglycolate phosphatase activity
AM480_RS08385	COG2378	regulation of single-species biofilm formation
AM480_RS08390	COG0625	glutathione transferase activity
AM480_RS08400	COG0583	DNA-binding transcription factor activity
AM480_RS08465	COG0473	3-isopropylmalate dehydrogenase activity
AM480_RS08520	COG1301	dicarboxylic acid transport
AM480_RS08530	COG1560	Kdo2-lipid A biosynthetic process
AM480_RS08535	COG1280	lysine exporter protein (LysE YggA)
AM480_RS08540	COG0488	(ABC) transporter
AM480_RS08545	COG2900	Belongs to the SlyX family
AM480_RS08555	COG1733	regulation of RNA biosynthetic process
AM480_RS08580	COG0210	DNA helicase
AM480_RS08585	COG0724	RNA recognition motif
AM480_RS08605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AM480_RS08605	COG4651	solute:proton antiporter activity
AM480_RS08630	COG0788	formyltetrahydrofolate deformylase activity
AM480_RS08730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM480_RS08730	COG2813	Specifically methylates the guanine in position
AM480_RS08740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AM480_RS08750	COG4774	siderophore transport
AM480_RS08760	COG0740	serine-type endopeptidase activity
AM480_RS08780	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AM480_RS08780	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AM480_RS08785	COG0280	phosphate acetyltransferase
AM480_RS08785	COG0857	belongs to the CobB CobQ family
AM480_RS08790	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AM480_RS08800	COG0800	Aldolase
AM480_RS08810	COG3265	gluconokinase activity
AM480_RS08815	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS08825	COG2267	carboxylic ester hydrolase activity
AM480_RS08840	COG0793	Belongs to the peptidase S41A family
AM480_RS08875	COG1426	Protein conserved in bacteria
AM480_RS08915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AM480_RS08925	COG1162	GTPase activity
AM480_RS08930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AM480_RS08945	COG1538	Outer membrane efflux protein
AM480_RS08950	COG1136	(ABC) transporter
AM480_RS08950	COG0577	efflux transmembrane transporter activity
AM480_RS08955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM480_RS08985	COG0028	Belongs to the TPP enzyme family
AM480_RS08990	COG0440	acetolactate synthase activity
AM480_RS09025	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AM480_RS09040	COG0084	hydrolase, TatD family'
AM480_RS09055	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AM480_RS09065	COG0583	DNA-binding transcription factor activity
AM480_RS09075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM480_RS09080	COG2814	Major facilitator Superfamily
AM480_RS09090	COG0697	spore germination
AM480_RS09120	COG3622	Belongs to the hyi family
AM480_RS09125	COG2084	Dehydrogenase
AM480_RS09130	COG1024	Enoyl-CoA hydratase
AM480_RS09135	COG5002	protein histidine kinase activity
AM480_RS09135	COG2205	protein histidine kinase activity
AM480_RS09135	COG0784	Response regulator, receiver
AM480_RS09155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AM480_RS09165	COG3956	TIGRFAM MazG family protein
AM480_RS09170	COG1555	photosystem II stabilization
AM480_RS09175	COG0617	tRNA 3'-terminal CCA addition
AM480_RS09180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AM480_RS09200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM480_RS09205	COG3028	Belongs to the UPF0307 family
AM480_RS09210	COG0318	PFAM AMP-dependent synthetase and ligase
AM480_RS09230	COG0625	glutathione transferase activity
AM480_RS09235	COG1238	metal cluster binding
AM480_RS09280	COG0072	phenylalanine-tRNA ligase activity
AM480_RS09310	COG0248	Ppx GppA phosphatase
AM480_RS09320	COG0037	tRNA processing
AM480_RS09360	COG1764	response to oxidative stress
AM480_RS09365	COG1846	Transcriptional regulator
AM480_RS09375	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM480_RS09435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AM480_RS09440	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AM480_RS09445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM480_RS09510	COG1214	PFAM Peptidase M22, glycoprotease
AM480_RS09525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AM480_RS09535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AM480_RS09540	COG0561	phosphatase activity
AM480_RS09550	COG2132	Multicopper oxidase
AM480_RS09570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AM480_RS09575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AM480_RS09580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AM480_RS09610	COG1063	alcohol dehydrogenase
AM480_RS09615	COG0583	DNA-binding transcription factor activity
AM480_RS09620	COG1960	acyl-CoA dehydrogenase activity
AM480_RS09625	COG2814	Major facilitator Superfamily
AM480_RS09630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AM480_RS09640	COG1053	succinate dehydrogenase
AM480_RS09645	COG0583	DNA-binding transcription factor activity
AM480_RS09665	COG0583	DNA-binding transcription factor activity
AM480_RS09695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS09750	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS09765	COG0384	phenazine biosynthesis protein PhzF
AM480_RS09775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AM480_RS09795	COG0745	RESPONSE REGULATOR receiver
AM480_RS09835	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AM480_RS09865	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AM480_RS09870	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AM480_RS09890	COG0583	DNA-binding transcription factor activity
AM480_RS09910	COG0668	transmembrane transport
AM480_RS09920	COG2081	HI0933 family
AM480_RS09925	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AM480_RS09955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM480_RS09955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AM480_RS09965	COG0489	protein tyrosine kinase activity
AM480_RS10025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AM480_RS10035	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AM480_RS10050	COG0730	response to heat
AM480_RS10060	COG1196	nuclear chromosome segregation
AM480_RS10080	COG2223	nitrite transmembrane transporter activity
AM480_RS10085	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AM480_RS10090	COG1877	trehalose-phosphatase activity
AM480_RS10095	COG0596	Alpha beta hydrolase
AM480_RS10095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM480_RS10095	COG2226	methyltransferase
AM480_RS10110	COG4106	trans-aconitate 2-methyltransferase activity
AM480_RS10125	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AM480_RS10130	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AM480_RS10135	COG0009	L-threonylcarbamoyladenylate synthase
AM480_RS10140	COG3101	peptidyl-lysine hydroxylation
AM480_RS10145	COG1399	metal-binding, possibly nucleic acid-binding protein
AM480_RS10170	COG1652	LysM domain
AM480_RS10175	COG0352	thiamine-phosphate diphosphorylase activity
AM480_RS10175	COG0351	phosphomethylpyrimidine kinase
AM480_RS10175	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AM480_RS10185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AM480_RS10215	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM480_RS10245	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AM480_RS10260	COG0358	DNA primase activity
AM480_RS10270	COG0564	pseudouridine synthase activity
AM480_RS10360	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS10370	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM480_RS10525	COG3646	Phage regulatory protein
AM480_RS10555	COG0739	heme binding
AM480_RS10610	COG0582	viral genome integration into host DNA
AM480_RS10620	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM480_RS10640	COG0583	DNA-binding transcription factor activity
AM480_RS10645	COG0473	3-isopropylmalate dehydrogenase activity
AM480_RS10655	COG0657	acetylesterase activity
AM480_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS10685	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM480_RS10685	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM480_RS10700	COG1981	membrane
AM480_RS10800	COG0305	Participates in initiation and elongation during chromosome replication
AM480_RS10930	COG1196	nuclear chromosome segregation
AM480_RS10930	COG0739	heme binding
AM480_RS10930	COG0741	lytic transglycosylase activity
AM480_RS10985	COG0582	viral genome integration into host DNA
AM480_RS10995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM480_RS11015	COG0583	DNA-binding transcription factor activity
AM480_RS11020	COG0473	3-isopropylmalate dehydrogenase activity
AM480_RS11030	COG0657	acetylesterase activity
AM480_RS11040	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS11060	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AM480_RS11060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AM480_RS11075	COG1981	membrane
AM480_RS11175	COG0305	Participates in initiation and elongation during chromosome replication
AM480_RS11305	COG0741	lytic transglycosylase activity
AM480_RS11305	COG0739	heme binding
AM480_RS11305	COG1196	nuclear chromosome segregation
AM480_RS11370	COG0456	acetyltransferase
AM480_RS11380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AM480_RS11385	COG0492	ferredoxin-NADP+ reductase activity
AM480_RS11390	COG1674	ftsk spoiiie
AM480_RS11395	COG1280	lysine exporter protein (LysE YggA)
AM480_RS11410	COG2894	cell division
AM480_RS11425	COG0204	Acyl-transferase
AM480_RS11430	COG2885	chlorophyll binding
AM480_RS11435	COG0210	DNA helicase
AM480_RS11445	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AM480_RS11460	COG0121	glutamine amidotransferase
AM480_RS11485	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AM480_RS11490	COG0735	belongs to the Fur family
AM480_RS11515	COG0420	3'-5' exonuclease activity
AM480_RS11535	COG1090	epimerase
AM480_RS11550	COG2050	protein possibly involved in aromatic compounds catabolism
AM480_RS11560	COG2814	Major facilitator Superfamily
AM480_RS11565	COG0405	Gamma-glutamyltransferase
AM480_RS11630	COG0477	Major facilitator Superfamily
AM480_RS11635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM480_RS11645	COG1595	DNA-templated transcription, initiation
AM480_RS11700	COG0531	amino acid
AM480_RS11705	COG2040	homocysteine
AM480_RS11730	COG1309	transcriptional regulator
AM480_RS11735	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM480_RS11740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AM480_RS11750	COG1607	acyl-coa hydrolase
AM480_RS11760	COG0523	cobalamin synthesis protein
AM480_RS11770	COG4681	YaeQ
AM480_RS11785	COG1215	transferase activity, transferring glycosyl groups
AM480_RS11810	COG1414	Transcriptional regulator
AM480_RS11845	COG2271	Major facilitator Superfamily
AM480_RS11855	COG2267	carboxylic ester hydrolase activity
AM480_RS11860	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS11875	COG0028	Belongs to the TPP enzyme family
AM480_RS11885	COG0477	Major facilitator Superfamily
AM480_RS11890	COG0242	peptide deformylase activity
AM480_RS11895	COG2066	Belongs to the glutaminase family
AM480_RS11900	COG2207	Transcriptional regulator
AM480_RS11905	COG2223	nitrite transmembrane transporter activity
AM480_RS11925	COG0583	DNA-binding transcription factor activity
AM480_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS11935	COG2271	Major facilitator Superfamily
AM480_RS11940	COG3959	Transketolase, thiamine diphosphate binding domain
AM480_RS11945	COG3958	Transketolase
AM480_RS11955	COG0306	phosphate transporter
AM480_RS11975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM480_RS12030	COG4181	ATPase activity
AM480_RS12065	COG0583	DNA-binding transcription factor activity
AM480_RS12075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM480_RS12080	COG1773	rubredoxin
AM480_RS12130	COG2851	Citrate transporter
AM480_RS12140	COG1253	flavin adenine dinucleotide binding
AM480_RS12185	COG0804	urea catabolic process
AM480_RS12195	COG0830	nickel cation binding
AM480_RS12210	COG0742	ribosomal rna small subunit methyltransferase
AM480_RS12215	COG0768	penicillin binding
AM480_RS12240	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AM480_RS12245	COG2878	Part of a membrane complex involved in electron transport
AM480_RS12250	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AM480_RS12260	COG3384	dioxygenase
AM480_RS12285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AM480_RS12465	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS12490	COG5410	chromosome segregation
AM480_RS12615	COG0739	heme binding
AM480_RS12660	COG2194	sulfuric ester hydrolase activity
AM480_RS12695	COG0006	proline dipeptidase activity
AM480_RS12700	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM480_RS12705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM480_RS12725	COG1279	arginine transmembrane transporter activity
AM480_RS12730	COG0583	DNA-binding transcription factor activity
AM480_RS12770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM480_RS12775	COG1388	LysM domain
AM480_RS12775	COG0741	lytic transglycosylase activity
AM480_RS12775	COG0741	lytic transglycosylase activity
AM480_RS12775	COG1388	LysM domain
AM480_RS12785	COG4174	ABC transporter (Permease)
AM480_RS12790	COG4239	(ABC) transporter, permease
AM480_RS12795	COG4172	Belongs to the ABC transporter superfamily
AM480_RS12815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM480_RS12825	COG2203	Gaf domain
AM480_RS12825	COG3706	GGDEF domain
AM480_RS12825	COG4251	negative regulation of phosphorylation
AM480_RS12825	COG5001	Diguanylate cyclase
AM480_RS12835	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM480_RS12835	COG1902	pentaerythritol trinitrate reductase activity
AM480_RS12895	COG3209	COG3209 Rhs family protein
AM480_RS12935	COG1113	amino acid transport
AM480_RS12945	COG0531	amino acid
AM480_RS12965	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS12985	COG1113	amino acid transport
AM480_RS13005	COG0697	spore germination
AM480_RS13010	COG2721	sulfolactate sulfo-lyase activity
AM480_RS13015	COG2271	Major facilitator Superfamily
AM480_RS13020	COG4948	Mandelate Racemase Muconate Lactonizing
AM480_RS13030	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS13035	COG2186	Transcriptional regulator
AM480_RS13070	COG1960	acyl-CoA dehydrogenase activity
AM480_RS13080	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS13085	COG1024	Enoyl-CoA hydratase
AM480_RS13090	COG2814	Major facilitator Superfamily
AM480_RS13105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM480_RS13120	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AM480_RS13165	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AM480_RS13170	COG2072	flavoprotein involved in K transport
AM480_RS13175	COG0300	oxidoreductase activity
AM480_RS13185	COG1309	transcriptional regulator
AM480_RS13190	COG1741	Belongs to the pirin family
AM480_RS13205	COG2072	flavoprotein involved in K transport
AM480_RS13215	COG2252	PERMEase
AM480_RS13220	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AM480_RS13225	COG3038	cytochrome b561
AM480_RS13235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AM480_RS13245	COG0527	aspartate kinase activity
AM480_RS13255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AM480_RS13265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AM480_RS13280	COG0667	Aldo Keto reductase
AM480_RS13290	COG1765	OsmC-like protein
AM480_RS13305	COG0542	response to heat
AM480_RS13340	COG2885	chlorophyll binding
AM480_RS13350	COG0625	glutathione transferase activity
AM480_RS13355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AM480_RS13375	COG3634	alkyl hydroperoxide reductase activity
AM480_RS13385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AM480_RS13395	COG0450	alkyl hydroperoxide reductase
AM480_RS13400	COG1643	Atp-dependent helicase
AM480_RS13415	COG2814	Major facilitator Superfamily
AM480_RS13420	COG3135	benzoate transporter
AM480_RS13425	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS13430	COG0633	Ferredoxin
AM480_RS13430	COG0543	2 iron, 2 sulfur cluster binding
AM480_RS13435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM480_RS13440	COG4638	Rieske (2fe-2S)
AM480_RS13445	COG0583	DNA-binding transcription factor activity
AM480_RS13455	COG2871	sodium ion transport
AM480_RS13585	COG1280	lysine exporter protein (LysE YggA)
AM480_RS13590	COG1278	Cold shock
AM480_RS13625	COG2814	Major facilitator Superfamily
AM480_RS13675	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AM480_RS13685	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AM480_RS13690	COG1137	ATPase activity
AM480_RS13695	COG1538	Outer membrane efflux protein
AM480_RS13725	COG4122	O-methyltransferase activity
AM480_RS13735	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AM480_RS13750	COG1522	sequence-specific DNA binding
AM480_RS13755	COG5006	permease, DMT superfamily
AM480_RS13765	COG1560	Kdo2-lipid A biosynthetic process
AM480_RS13780	COG2814	Major facilitator Superfamily
AM480_RS13790	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS13810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM480_RS13835	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM480_RS13910	COG0583	DNA-binding transcription factor activity
AM480_RS13915	COG1914	H( )-stimulated, divalent metal cation uptake system
AM480_RS13935	COG4770	biotin carboxylase activity
AM480_RS13940	COG0038	chloride channel
AM480_RS13965	COG1063	alcohol dehydrogenase
AM480_RS13980	COG0439	Biotin carboxylase
AM480_RS13985	COG2249	NAD(P)H dehydrogenase (quinone) activity
AM480_RS13990	COG1733	regulation of RNA biosynthetic process
AM480_RS14000	COG0864	Transcriptional regulator
AM480_RS14010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM480_RS14015	COG1116	anion transmembrane transporter activity
AM480_RS14135	COG0590	tRNA wobble adenosine to inosine editing
AM480_RS14155	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AM480_RS14165	COG0789	Transcriptional regulator
AM480_RS14180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AM480_RS14200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM480_RS14225	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS14230	COG0531	amino acid
AM480_RS14235	COG1760	l-serine dehydratase
AM480_RS14240	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS14240	COG2030	dehydratase
AM480_RS14245	COG3396	Phenylacetate-CoA oxygenase
AM480_RS14250	COG3460	Phenylacetate-CoA oxygenase
AM480_RS14255	COG3396	Phenylacetate-CoA oxygenase
AM480_RS14260	COG2151	metal-sulfur cluster biosynthetic enzyme
AM480_RS14265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM480_RS14270	COG1024	Enoyl-CoA hydratase
AM480_RS14275	COG1024	Enoyl-CoA hydratase
AM480_RS14280	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM480_RS14285	COG0183	Belongs to the thiolase family
AM480_RS14290	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AM480_RS14295	COG3327	negative regulation of DNA-templated transcription, initiation
AM480_RS14305	COG2050	protein possibly involved in aromatic compounds catabolism
AM480_RS14335	COG0753	catalase activity
AM480_RS14340	COG3038	cytochrome b561
AM480_RS14360	COG2267	carboxylic ester hydrolase activity
AM480_RS14365	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS14370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM480_RS14375	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS14385	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM480_RS14395	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS14400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM480_RS14405	COG0583	DNA-binding transcription factor activity
AM480_RS14415	COG1414	Transcriptional regulator
AM480_RS14420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AM480_RS14430	COG1840	ABC-type Fe3 transport system, periplasmic component
AM480_RS14435	COG3842	ATPase activity
AM480_RS14450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AM480_RS14455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AM480_RS14460	COG2814	Major facilitator Superfamily
AM480_RS14465	COG1960	acyl-CoA dehydrogenase activity
AM480_RS14480	COG1024	Enoyl-CoA hydratase
AM480_RS14495	COG2192	nodulation
AM480_RS14500	COG1280	lysine exporter protein (LysE YggA)
AM480_RS14515	COG0183	Belongs to the thiolase family
AM480_RS14520	COG1250	3-hydroxyacyl-CoA dehydrogenase
AM480_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS14530	COG1024	Enoyl-CoA hydratase
AM480_RS14535	COG1960	acyl-CoA dehydrogenase activity
AM480_RS14540	COG2814	Major facilitator Superfamily
AM480_RS14545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM480_RS14550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM480_RS14560	COG2814	Major facilitator Superfamily
AM480_RS14570	COG1960	acyl-CoA dehydrogenase activity
AM480_RS14585	COG0583	DNA-binding transcription factor activity
AM480_RS14595	COG4770	biotin carboxylase activity
AM480_RS14600	COG1024	Enoyl-CoA hydratase
AM480_RS14605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AM480_RS14610	COG1960	acyl-CoA dehydrogenase activity
AM480_RS14615	COG1309	transcriptional regulator
AM480_RS14620	COG0318	PFAM AMP-dependent synthetase and ligase
AM480_RS14640	COG0583	DNA-binding transcription factor activity
AM480_RS14685	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS14705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AM480_RS14725	COG2205	protein histidine kinase activity
AM480_RS14725	COG0784	Response regulator, receiver
AM480_RS14745	COG0765	amino acid transport
AM480_RS14750	COG0765	amino acid transport
AM480_RS14755	COG1126	abc transporter atp-binding protein
AM480_RS14760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM480_RS14765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AM480_RS14780	COG1280	lysine exporter protein (LysE YggA)
AM480_RS14790	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AM480_RS14795	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM480_RS14800	COG1045	serine acetyltransferase
AM480_RS14815	COG0583	DNA-binding transcription factor activity
AM480_RS14820	COG0625	glutathione transferase activity
AM480_RS14825	COG0625	glutathione transferase activity
AM480_RS14830	COG0583	DNA-binding transcription factor activity
AM480_RS14840	COG1346	cytolysis
AM480_RS14860	COG2814	Major facilitator Superfamily
AM480_RS14870	COG0583	DNA-binding transcription factor activity
AM480_RS14880	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AM480_RS14885	COG3052	prosthetic group binding
AM480_RS14905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AM480_RS14925	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM480_RS14935	COG1294	oxidase, subunit
AM480_RS14940	COG1271	oxidase subunit
AM480_RS14965	COG0477	Major facilitator Superfamily
AM480_RS15005	COG4521	taurine ABC transporter
AM480_RS15015	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM480_RS15020	COG2175	clavaminate synthase activity
AM480_RS15030	COG1953	Uracil, thiamine, allantoin
AM480_RS15040	COG0583	DNA-binding transcription factor activity
AM480_RS15050	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AM480_RS15065	COG0640	Transcriptional regulator
AM480_RS15070	COG0798	PFAM Bile acid sodium symporter
AM480_RS15075	COG0583	DNA-binding transcription factor activity
AM480_RS15090	COG3634	alkyl hydroperoxide reductase activity
AM480_RS15125	COG1301	dicarboxylic acid transport
AM480_RS15130	COG0436	Aminotransferase
AM480_RS15140	COG0386	Belongs to the glutathione peroxidase family
AM480_RS15155	COG0436	Aminotransferase
AM480_RS15180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AM480_RS15205	COG0012	GTP binding
AM480_RS15210	COG2011	ABC-type metal ion transport system permease component
AM480_RS15215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM480_RS15225	COG1464	Belongs to the NlpA lipoprotein family
AM480_RS15255	COG0765	amino acid transport
AM480_RS15260	COG0765	amino acid transport
AM480_RS15265	COG1126	abc transporter atp-binding protein
AM480_RS15275	COG1522	sequence-specific DNA binding
AM480_RS15290	COG1309	transcriptional regulator
AM480_RS15310	COG0583	DNA-binding transcription factor activity
AM480_RS15320	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AM480_RS15330	COG0697	spore germination
AM480_RS15360	COG3121	Chaperone
AM480_RS15365	COG3539	Fimbrial protein
AM480_RS15390	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AM480_RS15390	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AM480_RS15435	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AM480_RS15445	COG2353	YceI-like domain
AM480_RS15455	COG3698	Phosphodiester glycosidase
AM480_RS15470	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AM480_RS15475	COG0506	proline dehydrogenase activity
AM480_RS15475	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM480_RS15475	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AM480_RS15485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AM480_RS15490	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AM480_RS15510	COG1132	(ABC) transporter
AM480_RS15515	COG3122	Protein conserved in bacteria
AM480_RS15520	COG3619	membrane
AM480_RS15530	COG0640	Transcriptional regulator
AM480_RS15540	COG2850	peptidyl-arginine hydroxylation
AM480_RS15545	COG0424	maF-like protein
AM480_RS15565	COG0191	fructose-bisphosphate aldolase activity
AM480_RS15570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM480_RS15585	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AM480_RS15595	COG1192	Involved in chromosome partitioning
AM480_RS15600	COG1475	DNA binding
AM480_RS15605	COG0811	peptide transport
AM480_RS15615	COG1132	(ABC) transporter
AM480_RS15620	COG1663	tetraacyldisaccharide 4'-kinase activity
AM480_RS15640	COG0084	hydrolase, TatD family'
AM480_RS15705	COG0776	regulation of translation
AM480_RS15735	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AM480_RS15950	COG3646	Phage regulatory protein
AM480_RS15980	COG0739	heme binding
AM480_RS16035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AM480_RS16085	COG0339	signal peptide processing
AM480_RS16095	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AM480_RS16130	COG0702	epimerase
AM480_RS16135	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM480_RS16155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AM480_RS16185	COG0316	Belongs to the HesB IscA family
AM480_RS16190	COG0822	iron-sulfur transferase activity
AM480_RS16215	COG0776	regulation of translation
AM480_RS16220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AM480_RS16225	COG2207	Transcriptional regulator
AM480_RS16230	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM480_RS16235	COG1960	acyl-CoA dehydrogenase activity
AM480_RS16240	COG1960	acyl-CoA dehydrogenase activity
AM480_RS16255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AM480_RS16270	COG2814	Major facilitator Superfamily
AM480_RS16275	COG4264	IucA IucC family
AM480_RS16280	COG4264	IucA IucC family
AM480_RS16290	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AM480_RS16335	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AM480_RS16340	COG0406	alpha-ribazole phosphatase activity
AM480_RS16355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AM480_RS16360	COG0730	response to heat
AM480_RS16380	COG4773	Receptor
AM480_RS16385	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM480_RS16400	COG1131	(ABC) transporter
AM480_RS16405	COG0842	Transport permease protein
AM480_RS16410	COG0842	Transport permease protein
AM480_RS16465	COG2226	methyltransferase
AM480_RS16490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AM480_RS16510	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AM480_RS16515	COG2814	Major facilitator Superfamily
AM480_RS16525	COG0179	Fumarylacetoacetate (FAA) hydrolase
AM480_RS16535	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS16540	COG3384	dioxygenase
AM480_RS16550	COG3971	2-oxopent-4-enoate hydratase activity
AM480_RS16565	COG0477	Major facilitator Superfamily
AM480_RS16570	COG1960	acyl-CoA dehydrogenase activity
AM480_RS16575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS16580	COG1846	Transcriptional regulator
AM480_RS16585	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS16590	COG0129	dihydroxy-acid dehydratase activity
AM480_RS16600	COG0583	DNA-binding transcription factor activity
AM480_RS16605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AM480_RS16615	COG2084	Dehydrogenase
AM480_RS16620	COG2207	Transcriptional regulator
AM480_RS16630	COG1064	alcohol dehydrogenase
AM480_RS16640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AM480_RS16645	COG1120	ATPase activity
AM480_RS16665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AM480_RS16715	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AM480_RS16775	COG1073	alpha beta
AM480_RS16785	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS16795	COG2207	Transcriptional regulator
AM480_RS16805	COG2205	protein histidine kinase activity
AM480_RS16810	COG0745	RESPONSE REGULATOR receiver
AM480_RS16815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AM480_RS16820	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AM480_RS16835	COG2072	flavoprotein involved in K transport
AM480_RS16855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AM480_RS16880	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS16885	COG3938	Belongs to the proline racemase family
AM480_RS16900	COG2267	carboxylic ester hydrolase activity
AM480_RS16905	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
AM480_RS16910	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS16915	COG4580	involved in the transport of maltose and maltodextrins
AM480_RS16930	COG2223	nitrite transmembrane transporter activity
AM480_RS16940	COG0697	spore germination
AM480_RS16950	COG1609	Transcriptional regulator
AM480_RS16955	COG1346	cytolysis
AM480_RS16965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AM480_RS16970	COG0028	Belongs to the TPP enzyme family
AM480_RS16985	COG0483	inositol monophosphate 1-phosphatase activity
AM480_RS17000	COG4580	involved in the transport of maltose and maltodextrins
AM480_RS17010	COG0028	Belongs to the TPP enzyme family
AM480_RS17020	COG1609	Transcriptional regulator
AM480_RS17045	COG0494	nUDIX hydrolase
AM480_RS17050	COG0656	L-ascorbic acid biosynthetic process
AM480_RS17060	COG3539	Fimbrial protein
AM480_RS17085	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AM480_RS17095	COG0753	catalase activity
AM480_RS17110	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AM480_RS17175	COG0732	type I restriction modification DNA specificity domain
AM480_RS17185	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AM480_RS17200	COG1535	isochorismatase
AM480_RS17200	COG3433	isochorismatase activity
AM480_RS17205	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS17210	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AM480_RS17215	COG4149	molybdate abc transporter
AM480_RS17220	COG0725	ABC transporter, periplasmic molybdate-binding protein
AM480_RS17230	COG4638	Rieske (2fe-2S)
AM480_RS17235	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AM480_RS17240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AM480_RS17240	COG0543	2 iron, 2 sulfur cluster binding
AM480_RS17255	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS17265	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS17280	COG2207	Transcriptional regulator
AM480_RS17285	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS17290	COG2610	gluconate transmembrane transporter activity
AM480_RS17300	COG1309	transcriptional regulator
AM480_RS17320	COG0583	DNA-binding transcription factor activity
AM480_RS17335	COG2031	fatty acid transporter
AM480_RS17340	COG0183	Belongs to the thiolase family
AM480_RS17345	COG0583	DNA-binding transcription factor activity
AM480_RS17350	COG0583	DNA-binding transcription factor activity
AM480_RS17365	COG1027	Aspartate ammonia-lyase
AM480_RS17375	COG0477	Major facilitator Superfamily
AM480_RS17395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AM480_RS17400	COG4521	taurine ABC transporter
AM480_RS17415	COG2188	Transcriptional regulator
AM480_RS17425	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AM480_RS17430	COG1733	regulation of RNA biosynthetic process
AM480_RS17435	COG3708	Transcriptional regulator
AM480_RS17435	COG2207	Transcriptional regulator
AM480_RS17450	COG0730	response to heat
AM480_RS17460	COG3453	Protein conserved in bacteria
AM480_RS17460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM480_RS17470	COG3781	membrane
AM480_RS17475	COG1063	alcohol dehydrogenase
AM480_RS17485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AM480_RS17490	COG0508	dehydrogenase complex catalyzes the overall conversion of
AM480_RS17495	COG0022	dehydrogenase e1 component
AM480_RS17500	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AM480_RS17505	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AM480_RS17520	COG3706	GGDEF domain
AM480_RS17535	COG0133	tryptophan synthase activity
AM480_RS17540	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS17550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AM480_RS17600	COG0753	catalase activity
AM480_RS17615	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS17630	COG3162	membrane
AM480_RS17645	COG3829	transcription factor binding
AM480_RS17650	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS17655	COG1960	acyl-CoA dehydrogenase activity
AM480_RS17670	COG3231	kanamycin kinase activity
AM480_RS17675	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS17695	COG2186	Transcriptional regulator
AM480_RS17705	COG0583	DNA-binding transcription factor activity
AM480_RS17710	COG4948	Mandelate Racemase Muconate Lactonizing
AM480_RS17715	COG4829	muconolactone delta-isomerase
AM480_RS17725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM480_RS17730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM480_RS17735	COG0183	Belongs to the thiolase family
AM480_RS17740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AM480_RS17745	COG1012	belongs to the aldehyde dehydrogenase family
AM480_RS17755	COG3733	amine oxidase
AM480_RS17765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS17775	COG1028	Short-chain dehydrogenase reductase Sdr
AM480_RS17785	COG4638	Rieske (2fe-2S)
AM480_RS17805	COG0154	amidase activity
AM480_RS17815	COG2814	Major facilitator Superfamily
AM480_RS17840	COG1960	acyl-CoA dehydrogenase activity
AM480_RS17845	COG0583	DNA-binding transcription factor activity
AM480_RS17850	COG1414	Transcriptional regulator
AM480_RS17865	COG2391	methyltransferase activity
AM480_RS17875	COG4993	Dehydrogenase
AM480_RS17880	COG3659	wide pore channel activity
AM480_RS17885	COG3420	alginic acid biosynthetic process
AM480_RS17890	COG0710	3-dehydroquinate dehydratase activity
AM480_RS17895	COG3485	protocatechuate 3,4-dioxygenase
AM480_RS17900	COG3485	protocatechuate 3,4-dioxygenase
AM480_RS17905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AM480_RS17910	COG2271	Major facilitator Superfamily
AM480_RS17915	COG0596	Alpha beta hydrolase
AM480_RS17920	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AM480_RS17925	COG0183	Belongs to the thiolase family
AM480_RS17930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AM480_RS17935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AM480_RS17945	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AM480_RS17950	COG2323	membrane
AM480_RS17995	COG1902	pentaerythritol trinitrate reductase activity
AM480_RS17995	COG0446	pyridine nucleotide-disulphide oxidoreductase
AM480_RS18020	COG0542	response to heat
AM480_RS18025	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AM480_RS18055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AM480_RS18060	COG0569	domain protein
AM480_RS18065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AM480_RS18080	COG4774	siderophore transport
AM480_RS18085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AM480_RS18095	COG1585	Membrane protein implicated in regulation of membrane protease activity
AM480_RS18115	COG1294	oxidase, subunit
AM480_RS18120	COG4890	Cyd operon protein YbgT
AM480_RS18135	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AM480_RS18145	COG0552	protein localization to endoplasmic reticulum
AM480_RS18170	COG0517	IMP dehydrogenase activity
AM480_RS18170	COG0516	GMP reductase activity
AM480_RS18175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AM480_RS18180	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AM480_RS18190	COG0583	DNA-binding transcription factor activity
AM480_RS18195	COG0024	Methionine aminopeptidase
AM480_RS18225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AM480_RS18225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AM480_RS18230	COG1105	Belongs to the carbohydrate kinase PfkB family
AM480_RS18235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM480_RS18235	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AM480_RS18235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AM480_RS18300	COG0776	regulation of translation
AM480_RS18355	COG4373	Mu-like prophage FluMu protein gp28
AM480_RS18380	COG4383	Mu-like prophage protein gp29
AM480_RS18385	COG2369	cell adhesion
AM480_RS18485	COG3299	homolog of phage Mu protein gp47
AM480_RS18510	COG3300	MHYT domain
AM480_RS18510	COG5001	Diguanylate cyclase
AM480_RS18525	COG2135	peptidase activity
AM480_RS18530	COG0659	secondary active sulfate transmembrane transporter activity
AM480_RS18545	COG1113	amino acid transport
AM480_RS18555	COG1522	sequence-specific DNA binding
AM480_RS18580	COG1011	Hydrolase
AM480_RS18585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AM480_RS18595	COG2137	regulation of response to DNA damage stimulus
AM480_RS18610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AM480_RS18645	COG0575	Belongs to the CDS family
AM480_RS18650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AM480_RS18675	COG3852	Histidine kinase
AM480_RS18680	COG2204	response regulator
AM480_RS18740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AM480_RS18745	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AM480_RS18765	COG0697	spore germination
AM480_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM480_RS18780	COG0303	'Molybdopterin
AM480_RS18785	COG0315	cyclic pyranopterin monophosphate synthase activity
AM480_RS18785	COG0521	Mo-molybdopterin cofactor biosynthetic process
AM480_RS18800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AM480_RS18805	COG0243	molybdopterin cofactor binding
AM480_RS18815	COG0243	molybdopterin cofactor binding
AM480_RS18820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM480_RS18825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AM480_RS18825	COG2146	nitrite reductase [NAD(P)H] activity
AM480_RS18835	COG0745	RESPONSE REGULATOR receiver
AM480_RS18840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AM480_RS18840	COG1116	anion transmembrane transporter activity
AM480_RS18855	COG0511	ligase activity, forming carbon-carbon bonds
AM480_RS18870	COG2814	Major facilitator Superfamily
AM480_RS18890	COG0069	glutamate synthase activity
AM480_RS18910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AM480_RS18920	COG1454	alcohol dehydrogenase
AM480_RS18925	COG0824	Thioesterase
AM480_RS18935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AM480_RS18950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AM480_RS18955	COG2030	dehydratase
AM480_RS18965	COG0183	Belongs to the thiolase family
AM480_RS18975	COG0583	DNA-binding transcription factor activity
AM480_RS18980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AM480_RS18990	COG1522	sequence-specific DNA binding
AM480_RS18995	COG3135	benzoate transporter
AM480_RS19005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AM480_RS19025	COG0589	response to stress
AM480_RS19030	COG0488	(ABC) transporter
AM480_RS19050	COG4773	Receptor
AM480_RS19080	COG0668	transmembrane transport
AM480_RS19095	COG1309	transcriptional regulator
AM480_RS19115	COG1605	Chorismate mutase
AM480_RS19135	COG0308	aminopeptidase N
AM480_RS19165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AM480_RS19170	COG1454	alcohol dehydrogenase
AM480_RS19190	COG0531	amino acid
AM480_RS19195	COG4303	Ethanolamine ammonia lyase large subunit
AM480_RS19200	COG4302	ethanolamine ammonia-lyase activity
AM480_RS19205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AM480_RS19205	COG0519	Catalyzes the synthesis of GMP from XMP
AM480_RS19210	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AM480_RS19235	COG0697	spore germination
AM480_RS19240	COG1923	regulation of RNA biosynthetic process
AM480_RS19250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AM480_RS19255	COG0802	atpase or kinase
AM480_RS19275	COG1187	pseudouridine synthase activity
AM480_RS19290	COG0583	DNA-binding transcription factor activity
AM480_RS19305	COG2814	Major facilitator Superfamily
AM480_RS19310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AM480_RS19340	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AM480_RS19425	COG0592	DNA-directed DNA polymerase activity
AM480_RS19465	COG2026	Addiction module toxin, RelE StbE family
AM480_RS19685	COG1484	DNA-dependent DNA replication
AM480_RS19780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AM480_RS19820	COG0729	surface antigen
AM480_RS19840	COG0174	glutamine synthetase
AM480_RS19845	COG0745	RESPONSE REGULATOR receiver
AM480_RS19850	COG2205	protein histidine kinase activity
AM480_RS19860	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AM480_RS19865	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AM480_RS19890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AM480_RS19895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AM480_RS19900	COG1960	acyl-CoA dehydrogenase activity
AM480_RS19930	COG0583	DNA-binding transcription factor activity
AM480_RS19950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AM480_RS19960	COG3658	cytochrome
AM480_RS19965	COG1215	transferase activity, transferring glycosyl groups
AM480_RS19970	COG1649	PFAM Uncharacterised BCR, COG1649
AM480_RS19970	COG0726	polysaccharide deacetylase
AM480_RS19995	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AM480_RS20000	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AM480_RS20010	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AM480_RS20035	COG0305	Participates in initiation and elongation during chromosome replication
AM480_RS20040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AM480_RS20050	COG1305	Transglutaminase-like
AM480_RS20060	COG2308	Evidence 4 Homologs of previously reported genes of
AM480_RS20090	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AM480_RS20095	COG0138	bifunctional purine biosynthesis protein purh
AM480_RS20100	COG0151	Belongs to the GarS family
AM480_RS20105	COG1464	Belongs to the NlpA lipoprotein family
AM480_RS20110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AM480_RS20115	COG2011	ABC-type metal ion transport system permease component
AM480_RS20120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AM480_RS20130	COG1301	dicarboxylic acid transport
AM480_RS20160	COG1794	racemase activity, acting on amino acids and derivatives
AM480_RS20170	COG3008	intermembrane lipid transfer
AM480_RS20170	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AM480_RS20175	COG2995	paraquat-inducible protein a
AM480_RS20190	COG2985	domain, Protein
AM480_RS20215	COG0477	Major facilitator Superfamily
AM480_RS20255	COG2826	transposase and inactivated derivatives, IS30 family
AM480_RS20275	COG2186	Transcriptional regulator
AM480_RS20285	COG0786	glutamate:sodium symporter activity
AM480_RS20290	COG3243	poly(R)-hydroxyalkanoic acid synthase
AM480_RS20315	COG3111	PFAM Bacterial OB fold (BOF) protein
AM480_RS20405	COG2831	hemolysin activation secretion protein
AM480_RS20460	COG1610	YqeY-like protein
AM480_RS20490	COG1286	toxin biosynthetic process
AM480_RS20520	COG0778	Nitroreductase
AM480_RS20530	COG0513	Belongs to the DEAD box helicase family
AM480_RS20550	COG2363	Small membrane protein
AM480_RS20580	COG1234	tRNA 3'-trailer cleavage
AM480_RS20585	COG2195	Cleaves the N-terminal amino acid of tripeptides
AM480_RS20595	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AM480_RS20605	COG2819	hydrolase of the alpha beta superfamily
AM480_RS20610	COG1960	acyl-CoA dehydrogenase activity
AM480_RS20615	COG1301	dicarboxylic acid transport
AM480_RS20625	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AM480_RS20630	COG3139	Protein of unknown function (DUF1315)
AM480_RS20635	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AM480_RS20640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AM480_RS20650	COG0494	nUDIX hydrolase
AM480_RS20660	COG0642	Histidine kinase
AM480_RS20675	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AM480_RS20685	COG1720	tRNA m6t6A37 methyltransferase activity
AM480_RS20700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AM480_RS20705	COG0826	peptidase U32
AM480_RS20710	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AM480_RS20720	COG4598	ABC transporter
AM480_RS20725	COG4160	amino acid transport
AM480_RS20730	COG4215	(ABC) transporter
AM480_RS20745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family