locus-tag	class	description
ACX60_RS00010	COG0592	DNA-directed DNA polymerase activity
ACX60_RS00020	COG0187	DNA topoisomerase II activity
ACX60_RS00030	COG0586	Pfam SNARE associated Golgi protein
ACX60_RS00035	COG0488	(ABC) transporter
ACX60_RS00060	COG0596	Alpha beta hydrolase
ACX60_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACX60_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACX60_RS00110	COG0733	neurotransmitter:sodium symporter activity
ACX60_RS00150	COG2233	PERMEase
ACX60_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS00200	COG2814	Major facilitator Superfamily
ACX60_RS00205	COG0656	L-ascorbic acid biosynthetic process
ACX60_RS00210	COG0583	DNA-binding transcription factor activity
ACX60_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS00225	COG1064	alcohol dehydrogenase
ACX60_RS00230	COG2818	Glycosylase
ACX60_RS00245	COG1194	a g-specific adenine glycosylase
ACX60_RS00265	COG2983	Belongs to the UPF0260 family
ACX60_RS00270	COG2133	pyrroloquinoline quinone binding
ACX60_RS00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACX60_RS00280	COG2116	formate transmembrane transporter activity
ACX60_RS00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_RS00305	COG1335	isochorismatase
ACX60_RS00310	COG0385	Bile acid
ACX60_RS00315	COG0534	Mate efflux family protein
ACX60_RS00320	COG1683	Conserved Protein
ACX60_RS00340	COG0625	glutathione transferase activity
ACX60_RS00350	COG1113	amino acid transport
ACX60_RS00360	COG0523	cobalamin synthesis protein
ACX60_RS00370	COG2188	Transcriptional regulator
ACX60_RS00400	COG0010	Belongs to the arginase family
ACX60_RS00420	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACX60_RS00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACX60_RS00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACX60_RS00500	COG0753	catalase activity
ACX60_RS00550	COG0534	Mate efflux family protein
ACX60_RS00555	COG0436	Aminotransferase
ACX60_RS00560	COG2733	membrane
ACX60_RS00575	COG2918	glutathione biosynthetic process
ACX60_RS00605	COG1705	Flagellar rod assembly protein muramidase FlgJ
ACX60_RS00605	COG1388	LysM domain
ACX60_RS00645	COG3150	esterase
ACX60_RS00655	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACX60_RS00665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_RS00675	COG2233	PERMEase
ACX60_RS00680	COG2351	hydroxyisourate hydrolase activity
ACX60_RS00715	COG3706	GGDEF domain
ACX60_RS00730	COG1393	Belongs to the ArsC family
ACX60_RS00735	COG0708	Exodeoxyribonuclease III
ACX60_RS00760	COG0189	ligase activity
ACX60_RS00780	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACX60_RS00790	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACX60_RS00805	COG4942	peptidase
ACX60_RS00815	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX60_RS00825	COG2119	membrane
ACX60_RS00830	COG4774	siderophore transport
ACX60_RS00835	COG0426	domain, Protein
ACX60_RS00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_RS00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACX60_RS00880	COG1902	pentaerythritol trinitrate reductase activity
ACX60_RS00885	COG1519	Transferase
ACX60_RS00895	COG0668	transmembrane transport
ACX60_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_RS00910	COG1335	isochorismatase
ACX60_RS00915	COG1522	sequence-specific DNA binding
ACX60_RS00940	COG2205	protein histidine kinase activity
ACX60_RS00940	COG0784	Response regulator, receiver
ACX60_RS00940	COG2198	Histidine kinase
ACX60_RS00945	COG3162	membrane
ACX60_RS00950	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX60_RS00960	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_RS00975	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACX60_RS00980	COG1309	transcriptional regulator
ACX60_RS01000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX60_RS01000	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_RS01000	COG0351	phosphomethylpyrimidine kinase
ACX60_RS01010	COG2814	Major facilitator Superfamily
ACX60_RS01025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX60_RS01035	COG1113	amino acid transport
ACX60_RS01045	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX60_RS01050	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS01060	COG1335	isochorismatase
ACX60_RS01095	COG2814	Major facilitator Superfamily
ACX60_RS01100	COG0583	DNA-binding transcription factor activity
ACX60_RS01145	COG1733	regulation of RNA biosynthetic process
ACX60_RS01175	COG1733	regulation of RNA biosynthetic process
ACX60_RS01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS01200	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACX60_RS01205	COG2207	Transcriptional regulator
ACX60_RS01260	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACX60_RS01275	COG2329	Antibiotic biosynthesis monooxygenase
ACX60_RS01305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACX60_RS01335	COG0427	acetyl-CoA hydrolase
ACX60_RS01355	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_RS01360	COG4221	oxidoreductase activity
ACX60_RS01385	COG0488	(ABC) transporter
ACX60_RS01450	COG0833	amino acid
ACX60_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACX60_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACX60_RS01515	COG2226	methyltransferase
ACX60_RS01565	COG0067	glutamate synthase
ACX60_RS01565	COG0069	glutamate synthase activity
ACX60_RS01565	COG0070	glutamate synthase
ACX60_RS01570	COG0493	'glutamate synthase
ACX60_RS01580	COG1704	LemA family
ACX60_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACX60_RS01595	COG4969	Belongs to the N-Me-Phe pilin family
ACX60_RS01600	COG3307	-O-antigen
ACX60_RS01620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX60_RS01630	COG0194	GDP metabolic process
ACX60_RS01680	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACX60_RS01700	COG5380	lipid catabolic process
ACX60_RS01705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACX60_RS01730	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACX60_RS01735	COG0277	FAD linked oxidase domain protein
ACX60_RS01745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACX60_RS01750	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS01765	COG1289	transmembrane transporter activity
ACX60_RS01775	COG0628	permease
ACX60_RS01780	COG1192	Involved in chromosome partitioning
ACX60_RS01810	COG0833	amino acid
ACX60_RS01815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX60_RS01820	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX60_RS01830	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS01870	COG0583	DNA-binding transcription factor activity
ACX60_RS01920	COG0517	IMP dehydrogenase activity
ACX60_RS01925	COG1983	PspC domain protein
ACX60_RS01935	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS01950	COG0408	coproporphyrinogen oxidase activity
ACX60_RS01970	COG0513	Belongs to the DEAD box helicase family
ACX60_RS01980	COG1127	ABC transporter
ACX60_RS01985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACX60_RS01995	COG2854	intermembrane phospholipid transfer
ACX60_RS02005	COG0598	Magnesium transport protein CorA
ACX60_RS02015	COG0494	nUDIX hydrolase
ACX60_RS02020	COG1040	competence protein
ACX60_RS02025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACX60_RS02045	COG1946	Acyl-CoA thioesterase
ACX60_RS02050	COG1301	dicarboxylic acid transport
ACX60_RS02065	COG1959	2 iron, 2 sulfur cluster binding
ACX60_RS02070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_RS02070	COG1017	nitric oxide dioxygenase activity
ACX60_RS02075	COG0433	COG0433 Predicted ATPase
ACX60_RS02080	COG0626	cystathionine gamma-synthase activity
ACX60_RS02235	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS02240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACX60_RS02270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACX60_RS02275	COG0339	signal peptide processing
ACX60_RS02280	COG0557	exoribonuclease II activity
ACX60_RS02325	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACX60_RS02330	COG2169	Transcriptional regulator
ACX60_RS02335	COG0697	spore germination
ACX60_RS02340	COG1295	ribonuclease BN
ACX60_RS02375	COG1702	phosphate starvation-inducible protein PhoH
ACX60_RS02385	COG1196	nuclear chromosome segregation
ACX60_RS02385	COG0739	heme binding
ACX60_RS02385	COG0741	lytic transglycosylase activity
ACX60_RS02415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACX60_RS02420	COG1183	phosphatidylcholine synthase activity
ACX60_RS02465	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS02470	COG1309	transcriptional regulator
ACX60_RS02485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX60_RS02490	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS02510	COG2969	positive regulation of protein catabolic process
ACX60_RS02520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACX60_RS02530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACX60_RS02535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACX60_RS02540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACX60_RS02560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACX60_RS02570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX60_RS02575	COG1408	metallophosphoesterase
ACX60_RS02585	COG2199	diguanylate cyclase activity
ACX60_RS02645	COG1607	acyl-coa hydrolase
ACX60_RS02680	COG3013	Belongs to the UPF0304 family
ACX60_RS02755	COG2205	protein histidine kinase activity
ACX60_RS02770	COG2132	Multicopper oxidase
ACX60_RS02795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_RS02840	COG0582	viral genome integration into host DNA
ACX60_RS02865	COG2350	Protein conserved in bacteria
ACX60_RS02875	COG0613	PHP domain protein
ACX60_RS02880	COG3781	membrane
ACX60_RS02890	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACX60_RS02895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACX60_RS02905	COG1862	Preprotein translocase
ACX60_RS02935	COG0582	viral genome integration into host DNA
ACX60_RS02960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACX60_RS02975	COG2205	protein histidine kinase activity
ACX60_RS02980	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACX60_RS03000	COG0726	polysaccharide deacetylase
ACX60_RS03005	COG0463	Glycosyl transferase, family 2
ACX60_RS03010	COG0438	transferase activity, transferring glycosyl groups
ACX60_RS03025	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX60_RS03075	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS03080	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS03090	COG2205	protein histidine kinase activity
ACX60_RS03095	COG0745	RESPONSE REGULATOR receiver
ACX60_RS03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACX60_RS03120	COG2096	Adenosyltransferase
ACX60_RS03125	COG4206	TonB-dependent receptor
ACX60_RS03170	COG0285	dihydrofolate synthase activity
ACX60_RS03190	COG0450	alkyl hydroperoxide reductase
ACX60_RS03205	COG0477	Major facilitator Superfamily
ACX60_RS03210	COG1272	protein, Hemolysin III
ACX60_RS03220	COG2153	protein acetylation
ACX60_RS03240	COG0183	Belongs to the thiolase family
ACX60_RS03245	COG2207	Transcriptional regulator
ACX60_RS03265	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_RS03285	COG0183	Belongs to the thiolase family
ACX60_RS03305	COG1690	Belongs to the RtcB family
ACX60_RS03310	COG0833	amino acid
ACX60_RS03320	COG2233	PERMEase
ACX60_RS03325	COG1217	gtp-binding protein TYPA
ACX60_RS03350	COG2094	Belongs to the DNA glycosylase MPG family
ACX60_RS03355	COG4772	TonB-dependent receptor
ACX60_RS03360	COG1902	pentaerythritol trinitrate reductase activity
ACX60_RS03365	COG0679	Auxin Efflux Carrier
ACX60_RS03375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_RS03380	COG0354	folic acid binding
ACX60_RS03390	COG3189	MarR family transcriptional regulator
ACX60_RS03395	COG2824	Alkylphosphonate utilization operon protein PhnA
ACX60_RS03400	COG3422	double-strand break repair
ACX60_RS03440	COG0840	transmembrane signaling receptor activity
ACX60_RS03460	COG5510	response to toxic substance
ACX60_RS03470	COG2832	Protein of unknown function (DUF454)
ACX60_RS03475	COG1376	ErfK ybiS ycfS ynhG family protein
ACX60_RS03515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACX60_RS03525	COG1289	transmembrane transporter activity
ACX60_RS03530	COG2814	Major facilitator Superfamily
ACX60_RS03545	COG1115	amino acid carrier protein
ACX60_RS03550	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX60_RS03555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX60_RS03560	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACX60_RS03565	COG3590	peptidase
ACX60_RS03590	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX60_RS03600	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX60_RS03605	COG1077	Cell shape determining protein MreB Mrl
ACX60_RS03610	COG1792	Involved in formation and maintenance of cell shape
ACX60_RS03615	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACX60_RS03620	COG0424	maF-like protein
ACX60_RS03625	COG1530	ribonuclease E activity
ACX60_RS03635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS03645	COG0560	Phosphoserine phosphatase
ACX60_RS03655	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS03680	COG2207	Transcriptional regulator
ACX60_RS03700	COG1113	amino acid transport
ACX60_RS03705	COG2828	Protein conserved in bacteria
ACX60_RS03710	COG0142	geranyltranstransferase activity
ACX60_RS03715	COG2315	Protein conserved in bacteria
ACX60_RS03730	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX60_RS03750	COG2194	sulfuric ester hydrolase activity
ACX60_RS03755	COG0745	RESPONSE REGULATOR receiver
ACX60_RS03760	COG0642	Histidine kinase
ACX60_RS03770	COG0004	ammonium transporteR
ACX60_RS03775	COG0583	DNA-binding transcription factor activity
ACX60_RS03795	COG0525	valine-tRNA ligase activity
ACX60_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS03815	COG0393	Putative heavy-metal-binding
ACX60_RS03820	COG0393	Putative heavy-metal-binding
ACX60_RS03825	COG1538	Outer membrane efflux protein
ACX60_RS03835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS03840	COG0671	phosphoesterase, PA-phosphatase related
ACX60_RS03870	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACX60_RS03885	COG1648	precorrin-2 dehydrogenase activity
ACX60_RS03885	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACX60_RS03890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACX60_RS03895	COG1733	regulation of RNA biosynthetic process
ACX60_RS03905	COG0531	amino acid
ACX60_RS03920	COG0321	lipoyl(octanoyl) transferase activity
ACX60_RS03925	COG2921	Belongs to the UPF0250 family
ACX60_RS03965	COG2009	succinate dehydrogenase
ACX60_RS03970	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACX60_RS03975	COG1053	succinate dehydrogenase
ACX60_RS03980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACX60_RS03995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_RS04015	COG2354	Protein conserved in bacteria
ACX60_RS04020	COG2321	neutral zinc metallopeptidase
ACX60_RS04040	COG2843	Capsule synthesis protein
ACX60_RS04055	COG0589	response to stress
ACX60_RS04065	COG0251	oxidation-reduction process
ACX60_RS04070	COG1309	transcriptional regulator
ACX60_RS04085	COG0505	Belongs to the CarA family
ACX60_RS04110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX60_RS04115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACX60_RS04165	COG0477	Major facilitator Superfamily
ACX60_RS04170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACX60_RS04185	COG1597	lipid kinase activity
ACX60_RS04190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX60_RS04210	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_RS04215	COG0584	glycerophosphoryl diester phosphodiesterase
ACX60_RS04235	COG0741	lytic transglycosylase activity
ACX60_RS04255	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACX60_RS04270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS04280	COG3811	Belongs to the UPF0386 family
ACX60_RS04335	COG0778	Nitroreductase
ACX60_RS04350	COG1929	Belongs to the glycerate kinase type-1 family
ACX60_RS04355	COG0243	molybdopterin cofactor binding
ACX60_RS04360	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACX60_RS04365	COG3339	Conserved Protein
ACX60_RS04375	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACX60_RS04390	COG1113	amino acid transport
ACX60_RS04400	COG0019	diaminopimelate decarboxylase activity
ACX60_RS04410	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS04415	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX60_RS04445	COG0463	Glycosyl transferase, family 2
ACX60_RS04465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS04495	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACX60_RS04500	COG1136	(ABC) transporter
ACX60_RS04505	COG2333	competence protein COMEC
ACX60_RS04505	COG0658	competence protein
ACX60_RS04515	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACX60_RS04515	COG0616	signal peptide processing
ACX60_RS04520	COG0596	Alpha beta hydrolase
ACX60_RS04525	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACX60_RS04535	COG0628	permease
ACX60_RS04570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX60_RS04590	COG0823	Involved in the tonB-independent uptake of proteins
ACX60_RS04610	COG0824	Thioesterase
ACX60_RS04615	COG1473	amidohydrolase
ACX60_RS04635	COG0047	phosphoribosylformylglycinamidine synthase activity
ACX60_RS04635	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACX60_RS04640	COG2814	Major facilitator Superfamily
ACX60_RS04660	COG1169	isochorismate synthase
ACX60_RS04665	COG3433	isochorismatase activity
ACX60_RS04665	COG1535	isochorismatase
ACX60_RS04670	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS04675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS04680	COG3433	isochorismatase activity
ACX60_RS04680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS04680	COG2226	methyltransferase
ACX60_RS04685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS04690	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX60_RS04695	COG3486	L-lysine 6-monooxygenase (NADPH) activity
ACX60_RS04700	COG0019	diaminopimelate decarboxylase activity
ACX60_RS04725	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX60_RS04730	COG4774	siderophore transport
ACX60_RS04745	COG0534	Mate efflux family protein
ACX60_RS04755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS04830	COG1024	Enoyl-CoA hydratase
ACX60_RS04835	COG1056	cytidyltransferase-related domain
ACX60_RS04835	COG1051	belongs to the nudix hydrolase family
ACX60_RS04845	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACX60_RS04860	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACX60_RS04875	COG4625	pathogenesis
ACX60_RS04880	COG0583	DNA-binding transcription factor activity
ACX60_RS04885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACX60_RS04890	COG4208	sulfate ABC transporter
ACX60_RS04895	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACX60_RS04905	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACX60_RS04910	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACX60_RS04915	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACX60_RS04935	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX60_RS04945	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACX60_RS04955	COG0681	Belongs to the peptidase S26 family
ACX60_RS04970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACX60_RS04980	COG1381	Involved in DNA repair and RecF pathway recombination
ACX60_RS04985	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACX60_RS04995	COG4221	oxidoreductase activity
ACX60_RS05020	COG0443	Heat shock 70 kDa protein
ACX60_RS05030	COG0436	Aminotransferase
ACX60_RS05050	COG0556	nucleotide-excision repair
ACX60_RS05105	COG2070	2-Nitropropane dioxygenase
ACX60_RS05135	COG1215	transferase activity, transferring glycosyl groups
ACX60_RS05150	COG0415	Belongs to the DNA photolyase family
ACX60_RS05160	COG1252	NADH dehydrogenase
ACX60_RS05165	COG1686	Belongs to the peptidase S11 family
ACX60_RS05180	COG1187	pseudouridine synthase activity
ACX60_RS05200	COG0477	Major facilitator Superfamily
ACX60_RS05205	COG0583	DNA-binding transcription factor activity
ACX60_RS05210	COG1823	symporter activity
ACX60_RS05220	COG0612	Peptidase, M16
ACX60_RS05245	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_RS05280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_RS05290	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS05305	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX60_RS05310	COG0076	glutamate decarboxylase activity
ACX60_RS05320	COG1522	sequence-specific DNA binding
ACX60_RS05325	COG3961	Belongs to the TPP enzyme family
ACX60_RS05330	COG1113	amino acid transport
ACX60_RS05335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACX60_RS05340	COG0573	inorganic phosphate transmembrane transporter activity
ACX60_RS05350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACX60_RS05355	COG0616	signal peptide processing
ACX60_RS05390	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACX60_RS05395	COG1686	Belongs to the peptidase S11 family
ACX60_RS05420	COG0583	DNA-binding transcription factor activity
ACX60_RS05425	COG1067	ATP-dependent peptidase activity
ACX60_RS05450	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACX60_RS05470	COG1966	Carbon starvation protein
ACX60_RS05475	COG2879	small protein
ACX60_RS05515	COG1335	isochorismatase
ACX60_RS05520	COG0583	DNA-binding transcription factor activity
ACX60_RS05535	COG0596	Alpha beta hydrolase
ACX60_RS05545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX60_RS05575	COG1741	Belongs to the pirin family
ACX60_RS05585	COG2964	Protein conserved in bacteria
ACX60_RS05600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS05605	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX60_RS05610	COG4605	iron ion homeostasis
ACX60_RS05615	COG4604	ABC transporter, ATP-binding protein
ACX60_RS05620	COG4607	ABC-type enterochelin transport system periplasmic component
ACX60_RS05625	COG4774	siderophore transport
ACX60_RS05635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX60_RS05640	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX60_RS05645	COG3433	isochorismatase activity
ACX60_RS05645	COG1535	isochorismatase
ACX60_RS05660	COG1132	(ABC) transporter
ACX60_RS05665	COG1132	(ABC) transporter
ACX60_RS05670	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX60_RS05695	COG3739	integral membrane protein
ACX60_RS05715	COG0302	gtp cyclohydrolase
ACX60_RS05725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACX60_RS05755	COG0308	aminopeptidase N
ACX60_RS05760	COG0512	Glutamine amidotransferase of anthranilate synthase
ACX60_RS05775	COG0174	glutamine synthetase
ACX60_RS05785	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACX60_RS05820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACX60_RS05825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX60_RS05830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX60_RS05850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX60_RS05855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACX60_RS05860	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACX60_RS05875	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS05880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX60_RS05885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_RS05900	COG2223	nitrite transmembrane transporter activity
ACX60_RS05910	COG0024	Methionine aminopeptidase
ACX60_RS05915	COG0052	Belongs to the universal ribosomal protein uS2 family
ACX60_RS05930	COG2207	Transcriptional regulator
ACX60_RS05955	COG2951	lytic endotransglycosylase activity
ACX60_RS05960	COG0772	Belongs to the SEDS family
ACX60_RS05975	COG0842	Transport permease protein
ACX60_RS05980	COG1131	(ABC) transporter
ACX60_RS06020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS06035	COG4215	(ABC) transporter
ACX60_RS06040	COG4160	amino acid transport
ACX60_RS06045	COG4598	ABC transporter
ACX60_RS06055	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX60_RS06060	COG0826	peptidase U32
ACX60_RS06065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS06080	COG1720	tRNA m6t6A37 methyltransferase activity
ACX60_RS06090	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACX60_RS06105	COG0642	Histidine kinase
ACX60_RS06115	COG0494	nUDIX hydrolase
ACX60_RS06125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACX60_RS06130	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACX60_RS06135	COG3139	Protein of unknown function (DUF1315)
ACX60_RS06140	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACX60_RS06145	COG1301	dicarboxylic acid transport
ACX60_RS06150	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS06155	COG2819	hydrolase of the alpha beta superfamily
ACX60_RS06165	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACX60_RS06175	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACX60_RS06195	COG1690	Belongs to the RtcB family
ACX60_RS06200	COG1234	tRNA 3'-trailer cleavage
ACX60_RS06205	COG4650	regulator
ACX60_RS06235	COG2363	Small membrane protein
ACX60_RS06255	COG0513	Belongs to the DEAD box helicase family
ACX60_RS06265	COG0778	Nitroreductase
ACX60_RS06295	COG1286	toxin biosynthetic process
ACX60_RS06320	COG4783	chaperone-mediated protein folding
ACX60_RS06325	COG1610	YqeY-like protein
ACX60_RS06355	COG0515	serine threonine protein kinase
ACX60_RS06355	COG2815	serine threonine protein kinase
ACX60_RS06425	COG3111	PFAM Bacterial OB fold (BOF) protein
ACX60_RS06450	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACX60_RS06455	COG0786	glutamate:sodium symporter activity
ACX60_RS06465	COG2186	Transcriptional regulator
ACX60_RS06515	COG0477	Major facilitator Superfamily
ACX60_RS06520	COG1051	belongs to the nudix hydrolase family
ACX60_RS06550	COG2995	paraquat-inducible protein a
ACX60_RS06555	COG3008	intermembrane lipid transfer
ACX60_RS06555	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACX60_RS06570	COG1794	racemase activity, acting on amino acids and derivatives
ACX60_RS06600	COG1301	dicarboxylic acid transport
ACX60_RS06610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_RS06615	COG2011	ABC-type metal ion transport system permease component
ACX60_RS06620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX60_RS06625	COG1464	Belongs to the NlpA lipoprotein family
ACX60_RS06630	COG0151	Belongs to the GarS family
ACX60_RS06635	COG0138	bifunctional purine biosynthesis protein purh
ACX60_RS06640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACX60_RS06670	COG2308	Evidence 4 Homologs of previously reported genes of
ACX60_RS06680	COG1305	Transglutaminase-like
ACX60_RS06690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACX60_RS06695	COG0305	Participates in initiation and elongation during chromosome replication
ACX60_RS06720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACX60_RS06730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACX60_RS06735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACX60_RS06760	COG0726	polysaccharide deacetylase
ACX60_RS06760	COG1649	PFAM Uncharacterised BCR, COG1649
ACX60_RS06765	COG1215	transferase activity, transferring glycosyl groups
ACX60_RS06770	COG3658	cytochrome
ACX60_RS06780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX60_RS06795	COG0583	DNA-binding transcription factor activity
ACX60_RS06825	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS06830	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_RS06835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_RS06850	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACX60_RS06860	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACX60_RS06865	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACX60_RS06870	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACX60_RS06875	COG2205	protein histidine kinase activity
ACX60_RS06880	COG0745	RESPONSE REGULATOR receiver
ACX60_RS06885	COG0174	glutamine synthetase
ACX60_RS06905	COG0729	surface antigen
ACX60_RS06930	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX60_RS06935	COG2814	Major facilitator Superfamily
ACX60_RS06950	COG0583	DNA-binding transcription factor activity
ACX60_RS06965	COG1187	pseudouridine synthase activity
ACX60_RS06985	COG0802	atpase or kinase
ACX60_RS06990	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACX60_RS07000	COG1923	regulation of RNA biosynthetic process
ACX60_RS07005	COG0697	spore germination
ACX60_RS07030	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX60_RS07035	COG0519	Catalyzes the synthesis of GMP from XMP
ACX60_RS07035	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX60_RS07040	COG4302	ethanolamine ammonia-lyase activity
ACX60_RS07045	COG4303	Ethanolamine ammonia lyase large subunit
ACX60_RS07050	COG0531	amino acid
ACX60_RS07070	COG1454	alcohol dehydrogenase
ACX60_RS07075	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX60_RS07100	COG0308	aminopeptidase N
ACX60_RS07140	COG1605	Chorismate mutase
ACX60_RS07155	COG1309	transcriptional regulator
ACX60_RS07165	COG0668	transmembrane transport
ACX60_RS07195	COG4773	Receptor
ACX60_RS07215	COG0488	(ABC) transporter
ACX60_RS07220	COG0589	response to stress
ACX60_RS07240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACX60_RS07250	COG3135	benzoate transporter
ACX60_RS07255	COG1522	sequence-specific DNA binding
ACX60_RS07265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACX60_RS07270	COG0583	DNA-binding transcription factor activity
ACX60_RS07280	COG0183	Belongs to the thiolase family
ACX60_RS07290	COG2030	dehydratase
ACX60_RS07295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACX60_RS07310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACX60_RS07320	COG0824	Thioesterase
ACX60_RS07325	COG1454	alcohol dehydrogenase
ACX60_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACX60_RS07355	COG0069	glutamate synthase activity
ACX60_RS07500	COG3617	BRO family, N-terminal domain
ACX60_RS07535	COG5410	chromosome segregation
ACX60_RS07640	COG1598	PFAM Uncharacterised protein family UPF0150
ACX60_RS07700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX60_RS07715	COG2814	Major facilitator Superfamily
ACX60_RS07730	COG0511	ligase activity, forming carbon-carbon bonds
ACX60_RS07745	COG1116	anion transmembrane transporter activity
ACX60_RS07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_RS07750	COG0745	RESPONSE REGULATOR receiver
ACX60_RS07760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_RS07760	COG2146	nitrite reductase [NAD(P)H] activity
ACX60_RS07765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_RS07770	COG0243	molybdopterin cofactor binding
ACX60_RS07780	COG0243	molybdopterin cofactor binding
ACX60_RS07785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACX60_RS07800	COG0315	cyclic pyranopterin monophosphate synthase activity
ACX60_RS07800	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACX60_RS07805	COG0303	'Molybdopterin
ACX60_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS07820	COG0697	spore germination
ACX60_RS07840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACX60_RS07845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX60_RS07900	COG2204	response regulator
ACX60_RS07905	COG3852	Histidine kinase
ACX60_RS07925	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACX60_RS07930	COG0575	Belongs to the CDS family
ACX60_RS07945	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX60_RS07965	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX60_RS07975	COG2137	regulation of response to DNA damage stimulus
ACX60_RS07985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACX60_RS07990	COG1011	Hydrolase
ACX60_RS08015	COG1522	sequence-specific DNA binding
ACX60_RS08025	COG1113	amino acid transport
ACX60_RS08040	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_RS08045	COG2135	peptidase activity
ACX60_RS08060	COG3300	MHYT domain
ACX60_RS08060	COG5001	Diguanylate cyclase
ACX60_RS08075	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACX60_RS08075	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX60_RS08075	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX60_RS08080	COG1105	Belongs to the carbohydrate kinase PfkB family
ACX60_RS08085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACX60_RS08085	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX60_RS08115	COG0024	Methionine aminopeptidase
ACX60_RS08120	COG0583	DNA-binding transcription factor activity
ACX60_RS08130	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACX60_RS08135	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX60_RS08140	COG0517	IMP dehydrogenase activity
ACX60_RS08140	COG0516	GMP reductase activity
ACX60_RS08165	COG0552	protein localization to endoplasmic reticulum
ACX60_RS08175	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACX60_RS08190	COG4890	Cyd operon protein YbgT
ACX60_RS08195	COG1294	oxidase, subunit
ACX60_RS08210	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACX60_RS08220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACX60_RS08225	COG4774	siderophore transport
ACX60_RS08240	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACX60_RS08245	COG0569	domain protein
ACX60_RS08250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX60_RS08280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACX60_RS08285	COG0542	response to heat
ACX60_RS08310	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_RS08310	COG1902	pentaerythritol trinitrate reductase activity
ACX60_RS08355	COG2323	membrane
ACX60_RS08360	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACX60_RS08370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX60_RS08375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX60_RS08380	COG0183	Belongs to the thiolase family
ACX60_RS08385	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACX60_RS08390	COG0596	Alpha beta hydrolase
ACX60_RS08395	COG2271	Major facilitator Superfamily
ACX60_RS08400	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACX60_RS08405	COG3485	protocatechuate 3,4-dioxygenase
ACX60_RS08410	COG3485	protocatechuate 3,4-dioxygenase
ACX60_RS08415	COG0710	3-dehydroquinate dehydratase activity
ACX60_RS08420	COG3420	alginic acid biosynthetic process
ACX60_RS08425	COG3659	wide pore channel activity
ACX60_RS08430	COG4993	Dehydrogenase
ACX60_RS08440	COG2391	methyltransferase activity
ACX60_RS08455	COG1414	Transcriptional regulator
ACX60_RS08460	COG0583	DNA-binding transcription factor activity
ACX60_RS08465	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS08490	COG2814	Major facilitator Superfamily
ACX60_RS08500	COG0154	amidase activity
ACX60_RS08520	COG4638	Rieske (2fe-2S)
ACX60_RS08530	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS08540	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_RS08550	COG3733	amine oxidase
ACX60_RS08560	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS08570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_RS08575	COG0183	Belongs to the thiolase family
ACX60_RS08580	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX60_RS08585	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX60_RS08595	COG4829	muconolactone delta-isomerase
ACX60_RS08600	COG4948	Mandelate Racemase Muconate Lactonizing
ACX60_RS08605	COG0583	DNA-binding transcription factor activity
ACX60_RS08615	COG2186	Transcriptional regulator
ACX60_RS08635	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS08650	COG1902	pentaerythritol trinitrate reductase activity
ACX60_RS08650	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_RS08660	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACX60_RS08670	COG0789	Transcriptional regulator
ACX60_RS08695	COG1309	transcriptional regulator
ACX60_RS08700	COG0583	DNA-binding transcription factor activity
ACX60_RS08705	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS08710	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS08715	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS08725	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS08735	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS08820	COG2188	Transcriptional regulator
ACX60_RS08835	COG0583	DNA-binding transcription factor activity
ACX60_RS08850	COG1566	PFAM secretion protein HlyD family protein
ACX60_RS08865	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS08870	COG0129	dihydroxy-acid dehydratase activity
ACX60_RS08880	COG0583	DNA-binding transcription factor activity
ACX60_RS08885	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX60_RS08895	COG2084	Dehydrogenase
ACX60_RS08900	COG2207	Transcriptional regulator
ACX60_RS08905	COG1064	alcohol dehydrogenase
ACX60_RS08915	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX60_RS08920	COG1120	ATPase activity
ACX60_RS09015	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACX60_RS09050	COG2856	Zn peptidase
ACX60_RS09100	COG2207	Transcriptional regulator
ACX60_RS09115	COG2205	protein histidine kinase activity
ACX60_RS09120	COG0745	RESPONSE REGULATOR receiver
ACX60_RS09125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS09130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_RS09150	COG0543	2 iron, 2 sulfur cluster binding
ACX60_RS09150	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_RS09165	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS09190	COG2207	Transcriptional regulator
ACX60_RS09195	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS09200	COG2610	gluconate transmembrane transporter activity
ACX60_RS09210	COG1309	transcriptional regulator
ACX60_RS09230	COG0583	DNA-binding transcription factor activity
ACX60_RS09245	COG2031	fatty acid transporter
ACX60_RS09250	COG0183	Belongs to the thiolase family
ACX60_RS09255	COG0583	DNA-binding transcription factor activity
ACX60_RS09260	COG0583	DNA-binding transcription factor activity
ACX60_RS09275	COG1027	Aspartate ammonia-lyase
ACX60_RS09285	COG0477	Major facilitator Superfamily
ACX60_RS09305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_RS09310	COG4521	taurine ABC transporter
ACX60_RS09325	COG2188	Transcriptional regulator
ACX60_RS09335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACX60_RS09340	COG1733	regulation of RNA biosynthetic process
ACX60_RS09345	COG2207	Transcriptional regulator
ACX60_RS09345	COG3708	Transcriptional regulator
ACX60_RS09360	COG0730	response to heat
ACX60_RS09370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_RS09370	COG3453	Protein conserved in bacteria
ACX60_RS09380	COG3781	membrane
ACX60_RS09385	COG1063	alcohol dehydrogenase
ACX60_RS09395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX60_RS09400	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX60_RS09405	COG0022	dehydrogenase e1 component
ACX60_RS09410	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACX60_RS09415	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX60_RS09430	COG3706	GGDEF domain
ACX60_RS09445	COG0133	tryptophan synthase activity
ACX60_RS09455	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX60_RS09485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ACX60_RS09490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACX60_RS09515	COG2226	methyltransferase
ACX60_RS09570	COG0842	Transport permease protein
ACX60_RS09575	COG0842	Transport permease protein
ACX60_RS09580	COG1131	(ABC) transporter
ACX60_RS09595	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX60_RS09600	COG4773	Receptor
ACX60_RS09620	COG0730	response to heat
ACX60_RS09625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX60_RS09640	COG0406	alpha-ribazole phosphatase activity
ACX60_RS09645	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACX60_RS09660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX60_RS09690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX60_RS09700	COG4264	IucA IucC family
ACX60_RS09705	COG4264	IucA IucC family
ACX60_RS09710	COG2814	Major facilitator Superfamily
ACX60_RS09725	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACX60_RS09740	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS09745	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS09750	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX60_RS09755	COG2207	Transcriptional regulator
ACX60_RS09765	COG0776	regulation of translation
ACX60_RS09790	COG0822	iron-sulfur transferase activity
ACX60_RS09795	COG0316	Belongs to the HesB IscA family
ACX60_RS09825	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACX60_RS09845	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX60_RS09850	COG0702	epimerase
ACX60_RS09885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACX60_RS09895	COG0339	signal peptide processing
ACX60_RS09940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACX60_RS10050	COG4695	Portal protein
ACX60_RS10125	COG0305	Participates in initiation and elongation during chromosome replication
ACX60_RS10200	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACX60_RS10230	COG0776	regulation of translation
ACX60_RS10295	COG0084	hydrolase, TatD family'
ACX60_RS10315	COG1663	tetraacyldisaccharide 4'-kinase activity
ACX60_RS10320	COG1132	(ABC) transporter
ACX60_RS10330	COG0811	peptide transport
ACX60_RS10335	COG1475	DNA binding
ACX60_RS10340	COG1192	Involved in chromosome partitioning
ACX60_RS10350	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX60_RS10365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX60_RS10370	COG0191	fructose-bisphosphate aldolase activity
ACX60_RS10390	COG0424	maF-like protein
ACX60_RS10395	COG2850	peptidyl-arginine hydroxylation
ACX60_RS10405	COG0640	Transcriptional regulator
ACX60_RS10415	COG3619	membrane
ACX60_RS10420	COG3122	Protein conserved in bacteria
ACX60_RS10425	COG1132	(ABC) transporter
ACX60_RS10445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACX60_RS10450	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX60_RS10460	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX60_RS10460	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX60_RS10460	COG0506	proline dehydrogenase activity
ACX60_RS10465	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACX60_RS10480	COG3698	Phosphodiester glycosidase
ACX60_RS10490	COG2353	YceI-like domain
ACX60_RS10500	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACX60_RS10545	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACX60_RS10545	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACX60_RS10570	COG3539	Fimbrial protein
ACX60_RS10575	COG3121	Chaperone
ACX60_RS10600	COG0697	spore germination
ACX60_RS10610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACX60_RS10620	COG0583	DNA-binding transcription factor activity
ACX60_RS10640	COG1309	transcriptional regulator
ACX60_RS10655	COG1522	sequence-specific DNA binding
ACX60_RS10665	COG1126	abc transporter atp-binding protein
ACX60_RS10670	COG0765	amino acid transport
ACX60_RS10675	COG0765	amino acid transport
ACX60_RS10705	COG1464	Belongs to the NlpA lipoprotein family
ACX60_RS10715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX60_RS10720	COG2011	ABC-type metal ion transport system permease component
ACX60_RS10725	COG0012	GTP binding
ACX60_RS10750	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX60_RS10790	COG0386	Belongs to the glutathione peroxidase family
ACX60_RS10800	COG0436	Aminotransferase
ACX60_RS10805	COG1301	dicarboxylic acid transport
ACX60_RS10840	COG3634	alkyl hydroperoxide reductase activity
ACX60_RS10855	COG0583	DNA-binding transcription factor activity
ACX60_RS10860	COG0798	PFAM Bile acid sodium symporter
ACX60_RS10865	COG0640	Transcriptional regulator
ACX60_RS10880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACX60_RS10890	COG0583	DNA-binding transcription factor activity
ACX60_RS10900	COG1953	Uracil, thiamine, allantoin
ACX60_RS10910	COG2175	clavaminate synthase activity
ACX60_RS10915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_RS10920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACX60_RS10925	COG4521	taurine ABC transporter
ACX60_RS10935	COG0477	Major facilitator Superfamily
ACX60_RS10955	COG1271	oxidase subunit
ACX60_RS10960	COG1294	oxidase, subunit
ACX60_RS10970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS10990	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACX60_RS11010	COG3052	prosthetic group binding
ACX60_RS11015	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACX60_RS11025	COG0583	DNA-binding transcription factor activity
ACX60_RS11035	COG2814	Major facilitator Superfamily
ACX60_RS11050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS11055	COG1346	cytolysis
ACX60_RS11065	COG0583	DNA-binding transcription factor activity
ACX60_RS11070	COG0625	glutathione transferase activity
ACX60_RS11075	COG0625	glutathione transferase activity
ACX60_RS11080	COG0583	DNA-binding transcription factor activity
ACX60_RS11095	COG1045	serine acetyltransferase
ACX60_RS11100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX60_RS11105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACX60_RS11120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_RS11135	COG0765	amino acid transport
ACX60_RS11140	COG0765	amino acid transport
ACX60_RS11155	COG2205	protein histidine kinase activity
ACX60_RS11155	COG0784	Response regulator, receiver
ACX60_RS11195	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS11245	COG0583	DNA-binding transcription factor activity
ACX60_RS11265	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS11270	COG1309	transcriptional regulator
ACX60_RS11275	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS11280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX60_RS11285	COG1024	Enoyl-CoA hydratase
ACX60_RS11290	COG4770	biotin carboxylase activity
ACX60_RS11300	COG0583	DNA-binding transcription factor activity
ACX60_RS11320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX60_RS11325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACX60_RS11340	COG3842	ATPase activity
ACX60_RS11345	COG1840	ABC-type Fe3 transport system, periplasmic component
ACX60_RS11360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_RS11365	COG1414	Transcriptional regulator
ACX60_RS11375	COG0583	DNA-binding transcription factor activity
ACX60_RS11380	COG3038	cytochrome b561
ACX60_RS11385	COG0753	catalase activity
ACX60_RS11415	COG2050	protein possibly involved in aromatic compounds catabolism
ACX60_RS11425	COG3327	negative regulation of DNA-templated transcription, initiation
ACX60_RS11430	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACX60_RS11435	COG0183	Belongs to the thiolase family
ACX60_RS11440	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX60_RS11445	COG1024	Enoyl-CoA hydratase
ACX60_RS11450	COG1024	Enoyl-CoA hydratase
ACX60_RS11455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_RS11460	COG2151	metal-sulfur cluster biosynthetic enzyme
ACX60_RS11465	COG3396	Phenylacetate-CoA oxygenase
ACX60_RS11470	COG3460	Phenylacetate-CoA oxygenase
ACX60_RS11475	COG3396	Phenylacetate-CoA oxygenase
ACX60_RS11480	COG2030	dehydratase
ACX60_RS11480	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS11485	COG1760	l-serine dehydratase
ACX60_RS11490	COG0531	amino acid
ACX60_RS11495	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS11520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACX60_RS11540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_RS11550	COG0789	Transcriptional regulator
ACX60_RS11560	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACX60_RS11575	COG2807	transmembrane transport
ACX60_RS11580	COG0590	tRNA wobble adenosine to inosine editing
ACX60_RS11685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX60_RS11710	COG1116	anion transmembrane transporter activity
ACX60_RS11715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX60_RS11725	COG0864	Transcriptional regulator
ACX60_RS11740	COG1733	regulation of RNA biosynthetic process
ACX60_RS11745	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS11750	COG0439	Biotin carboxylase
ACX60_RS11765	COG1063	alcohol dehydrogenase
ACX60_RS11775	COG1309	transcriptional regulator
ACX60_RS11785	COG0038	chloride channel
ACX60_RS11790	COG4770	biotin carboxylase activity
ACX60_RS11810	COG1914	H( )-stimulated, divalent metal cation uptake system
ACX60_RS11815	COG0583	DNA-binding transcription factor activity
ACX60_RS11845	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX60_RS11865	COG2814	Major facilitator Superfamily
ACX60_RS11880	COG0598	Magnesium transport protein CorA
ACX60_RS11885	COG1560	Kdo2-lipid A biosynthetic process
ACX60_RS11900	COG1522	sequence-specific DNA binding
ACX60_RS11915	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACX60_RS11925	COG4122	O-methyltransferase activity
ACX60_RS11955	COG1538	Outer membrane efflux protein
ACX60_RS11960	COG1137	ATPase activity
ACX60_RS11965	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACX60_RS11975	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACX60_RS11980	COG0517	IMP dehydrogenase activity
ACX60_RS11980	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ACX60_RS12020	COG2814	Major facilitator Superfamily
ACX60_RS12050	COG1278	Cold shock
ACX60_RS12055	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS12090	COG1570	exodeoxyribonuclease VII activity
ACX60_RS12145	COG0583	DNA-binding transcription factor activity
ACX60_RS12150	COG4638	Rieske (2fe-2S)
ACX60_RS12155	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX60_RS12160	COG0633	Ferredoxin
ACX60_RS12160	COG0543	2 iron, 2 sulfur cluster binding
ACX60_RS12165	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS12170	COG3135	benzoate transporter
ACX60_RS12175	COG2814	Major facilitator Superfamily
ACX60_RS12190	COG1643	Atp-dependent helicase
ACX60_RS12195	COG0450	alkyl hydroperoxide reductase
ACX60_RS12205	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACX60_RS12215	COG3634	alkyl hydroperoxide reductase activity
ACX60_RS12235	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACX60_RS12240	COG0625	glutathione transferase activity
ACX60_RS12250	COG2885	chlorophyll binding
ACX60_RS12285	COG0542	response to heat
ACX60_RS12300	COG1765	OsmC-like protein
ACX60_RS12310	COG0667	Aldo Keto reductase
ACX60_RS12325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACX60_RS12345	COG0582	viral genome integration into host DNA
ACX60_RS12480	COG3566	protein conserved in bacteria
ACX60_RS12505	COG3567	Phage-associated protein, HI1409 family
ACX60_RS12510	COG5410	chromosome segregation
ACX60_RS12590	COG4197	protein conserved in bacteria, prophage-related
ACX60_RS12595	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACX60_RS12645	COG0527	aspartate kinase activity
ACX60_RS12655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACX60_RS12665	COG3038	cytochrome b561
ACX60_RS12670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACX60_RS12675	COG2252	PERMEase
ACX60_RS12685	COG2072	flavoprotein involved in K transport
ACX60_RS12700	COG1741	Belongs to the pirin family
ACX60_RS12705	COG1309	transcriptional regulator
ACX60_RS12715	COG0300	oxidoreductase activity
ACX60_RS12720	COG2072	flavoprotein involved in K transport
ACX60_RS12725	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACX60_RS12770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX60_RS12785	COG2814	Major facilitator Superfamily
ACX60_RS12790	COG1024	Enoyl-CoA hydratase
ACX60_RS12795	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS12805	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS12830	COG2186	Transcriptional regulator
ACX60_RS12835	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS12845	COG4948	Mandelate Racemase Muconate Lactonizing
ACX60_RS12850	COG2271	Major facilitator Superfamily
ACX60_RS12855	COG2721	sulfolactate sulfo-lyase activity
ACX60_RS12860	COG0697	spore germination
ACX60_RS12890	COG1113	amino acid transport
ACX60_RS12910	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS12930	COG0531	amino acid
ACX60_RS12940	COG1113	amino acid transport
ACX60_RS12985	COG0583	DNA-binding transcription factor activity
ACX60_RS12995	COG0251	oxidation-reduction process
ACX60_RS13035	COG1902	pentaerythritol trinitrate reductase activity
ACX60_RS13035	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_RS13050	COG5001	Diguanylate cyclase
ACX60_RS13050	COG2203	Gaf domain
ACX60_RS13050	COG3706	GGDEF domain
ACX60_RS13050	COG4251	negative regulation of phosphorylation
ACX60_RS13060	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX60_RS13080	COG4172	Belongs to the ABC transporter superfamily
ACX60_RS13085	COG4239	(ABC) transporter, permease
ACX60_RS13090	COG4174	ABC transporter (Permease)
ACX60_RS13100	COG1388	LysM domain
ACX60_RS13100	COG0741	lytic transglycosylase activity
ACX60_RS13100	COG1388	LysM domain
ACX60_RS13100	COG0741	lytic transglycosylase activity
ACX60_RS13105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX60_RS13145	COG0583	DNA-binding transcription factor activity
ACX60_RS13150	COG1279	arginine transmembrane transporter activity
ACX60_RS13170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_RS13175	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX60_RS13180	COG0006	proline dipeptidase activity
ACX60_RS13210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACX60_RS13235	COG3384	dioxygenase
ACX60_RS13245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX60_RS13250	COG2878	Part of a membrane complex involved in electron transport
ACX60_RS13255	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACX60_RS13275	COG0768	penicillin binding
ACX60_RS13280	COG0742	ribosomal rna small subunit methyltransferase
ACX60_RS13295	COG0830	nickel cation binding
ACX60_RS13305	COG0804	urea catabolic process
ACX60_RS13350	COG1253	flavin adenine dinucleotide binding
ACX60_RS13355	COG2851	Citrate transporter
ACX60_RS13400	COG1773	rubredoxin
ACX60_RS13405	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX60_RS13415	COG0583	DNA-binding transcription factor activity
ACX60_RS13440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACX60_RS13445	COG4181	ATPase activity
ACX60_RS13490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX60_RS13510	COG0306	phosphate transporter
ACX60_RS13520	COG3958	Transketolase
ACX60_RS13525	COG3959	Transketolase, thiamine diphosphate binding domain
ACX60_RS13530	COG2271	Major facilitator Superfamily
ACX60_RS13535	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS13540	COG0583	DNA-binding transcription factor activity
ACX60_RS13560	COG2223	nitrite transmembrane transporter activity
ACX60_RS13565	COG2207	Transcriptional regulator
ACX60_RS13570	COG2066	Belongs to the glutaminase family
ACX60_RS13575	COG0242	peptide deformylase activity
ACX60_RS13580	COG0477	Major facilitator Superfamily
ACX60_RS13590	COG0028	Belongs to the TPP enzyme family
ACX60_RS13605	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS13610	COG2267	carboxylic ester hydrolase activity
ACX60_RS13620	COG2271	Major facilitator Superfamily
ACX60_RS13625	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX60_RS13635	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS13655	COG1414	Transcriptional regulator
ACX60_RS13670	COG1024	Enoyl-CoA hydratase
ACX60_RS13680	COG1215	transferase activity, transferring glycosyl groups
ACX60_RS13685	COG0726	polysaccharide deacetylase
ACX60_RS13685	COG1649	PFAM Uncharacterised BCR, COG1649
ACX60_RS13695	COG4681	YaeQ
ACX60_RS13705	COG0523	cobalamin synthesis protein
ACX60_RS13715	COG1607	acyl-coa hydrolase
ACX60_RS13725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_RS13730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX60_RS13735	COG1309	transcriptional regulator
ACX60_RS13760	COG2040	homocysteine
ACX60_RS13765	COG0531	amino acid
ACX60_RS13790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_RS13795	COG0477	Major facilitator Superfamily
ACX60_RS13830	COG0405	Gamma-glutamyltransferase
ACX60_RS13835	COG2814	Major facilitator Superfamily
ACX60_RS13845	COG2050	protein possibly involved in aromatic compounds catabolism
ACX60_RS13860	COG1090	epimerase
ACX60_RS13880	COG0420	3'-5' exonuclease activity
ACX60_RS13905	COG0735	belongs to the Fur family
ACX60_RS13910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX60_RS13930	COG0121	glutamine amidotransferase
ACX60_RS13945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX60_RS13955	COG0210	DNA helicase
ACX60_RS13960	COG2885	chlorophyll binding
ACX60_RS13965	COG0204	Acyl-transferase
ACX60_RS13980	COG2894	cell division
ACX60_RS13995	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS14000	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACX60_RS14000	COG1674	ftsk spoiiie
ACX60_RS14005	COG0492	ferredoxin-NADP+ reductase activity
ACX60_RS14010	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACX60_RS14020	COG0456	acetyltransferase
ACX60_RS14065	COG1981	membrane
ACX60_RS14080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX60_RS14080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACX60_RS14100	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS14110	COG0657	acetylesterase activity
ACX60_RS14120	COG0473	3-isopropylmalate dehydrogenase activity
ACX60_RS14125	COG0583	DNA-binding transcription factor activity
ACX60_RS14140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX60_RS14165	COG0564	pseudouridine synthase activity
ACX60_RS14175	COG0358	DNA primase activity
ACX60_RS14190	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACX60_RS14220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX60_RS14250	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACX60_RS14260	COG0352	thiamine-phosphate diphosphorylase activity
ACX60_RS14260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX60_RS14260	COG0351	phosphomethylpyrimidine kinase
ACX60_RS14265	COG1652	LysM domain
ACX60_RS14290	COG1399	metal-binding, possibly nucleic acid-binding protein
ACX60_RS14295	COG3101	peptidyl-lysine hydroxylation
ACX60_RS14300	COG0009	L-threonylcarbamoyladenylate synthase
ACX60_RS14305	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACX60_RS14310	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACX60_RS14325	COG4106	trans-aconitate 2-methyltransferase activity
ACX60_RS14340	COG0596	Alpha beta hydrolase
ACX60_RS14340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_RS14340	COG2226	methyltransferase
ACX60_RS14345	COG1877	trehalose-phosphatase activity
ACX60_RS14350	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACX60_RS14355	COG2223	nitrite transmembrane transporter activity
ACX60_RS14375	COG1196	nuclear chromosome segregation
ACX60_RS14385	COG0730	response to heat
ACX60_RS14400	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACX60_RS14410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX60_RS14460	COG0489	protein tyrosine kinase activity
ACX60_RS14470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_RS14470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_RS14500	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACX60_RS14505	COG2081	HI0933 family
ACX60_RS14515	COG0668	transmembrane transport
ACX60_RS14535	COG0583	DNA-binding transcription factor activity
ACX60_RS14560	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACX60_RS14565	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX60_RS14595	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACX60_RS14635	COG0745	RESPONSE REGULATOR receiver
ACX60_RS14650	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACX60_RS14695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX60_RS14710	COG0583	DNA-binding transcription factor activity
ACX60_RS14740	COG0583	DNA-binding transcription factor activity
ACX60_RS14755	COG0583	DNA-binding transcription factor activity
ACX60_RS14760	COG1053	succinate dehydrogenase
ACX60_RS14770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACX60_RS14775	COG2814	Major facilitator Superfamily
ACX60_RS14780	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS14785	COG0583	DNA-binding transcription factor activity
ACX60_RS14790	COG1063	alcohol dehydrogenase
ACX60_RS14820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACX60_RS14825	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACX60_RS14830	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX60_RS14850	COG2132	Multicopper oxidase
ACX60_RS14860	COG0561	phosphatase activity
ACX60_RS14865	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACX60_RS14890	COG1214	PFAM Peptidase M22, glycoprotease
ACX60_RS14940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACX60_RS14950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACX60_RS14955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACX60_RS14960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACX60_RS15020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX60_RS15030	COG1846	Transcriptional regulator
ACX60_RS15035	COG1764	response to oxidative stress
ACX60_RS15075	COG0037	tRNA processing
ACX60_RS15085	COG0248	Ppx GppA phosphatase
ACX60_RS15110	COG0072	phenylalanine-tRNA ligase activity
ACX60_RS15150	COG1238	metal cluster binding
ACX60_RS15155	COG0625	glutathione transferase activity
ACX60_RS15170	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS15175	COG3028	Belongs to the UPF0307 family
ACX60_RS15180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX60_RS15200	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACX60_RS15205	COG0617	tRNA 3'-terminal CCA addition
ACX60_RS15210	COG1555	photosystem II stabilization
ACX60_RS15215	COG3956	TIGRFAM MazG family protein
ACX60_RS15225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX60_RS15245	COG0784	Response regulator, receiver
ACX60_RS15245	COG2205	protein histidine kinase activity
ACX60_RS15245	COG5002	protein histidine kinase activity
ACX60_RS15250	COG1024	Enoyl-CoA hydratase
ACX60_RS15255	COG2084	Dehydrogenase
ACX60_RS15260	COG3622	Belongs to the hyi family
ACX60_RS15290	COG0697	spore germination
ACX60_RS15300	COG2814	Major facilitator Superfamily
ACX60_RS15305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX60_RS15315	COG0583	DNA-binding transcription factor activity
ACX60_RS15320	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACX60_RS15330	COG0084	hydrolase, TatD family'
ACX60_RS15345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACX60_RS15395	COG0440	acetolactate synthase activity
ACX60_RS15400	COG0028	Belongs to the TPP enzyme family
ACX60_RS15425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX60_RS15430	COG0577	efflux transmembrane transporter activity
ACX60_RS15430	COG1136	(ABC) transporter
ACX60_RS15435	COG1538	Outer membrane efflux protein
ACX60_RS15450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACX60_RS15455	COG1162	GTPase activity
ACX60_RS15465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACX60_RS15485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACX60_RS15490	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS15530	COG2986	histidine ammonia-lyase
ACX60_RS15540	COG1216	Glycosyl transferase, family 2
ACX60_RS15545	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS15555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACX60_RS15600	COG1426	Protein conserved in bacteria
ACX60_RS15635	COG0793	Belongs to the peptidase S41A family
ACX60_RS15650	COG2267	carboxylic ester hydrolase activity
ACX60_RS15660	COG1012	belongs to the aldehyde dehydrogenase family
ACX60_RS15665	COG3265	gluconokinase activity
ACX60_RS15675	COG0800	Aldolase
ACX60_RS15685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACX60_RS15690	COG0280	phosphate acetyltransferase
ACX60_RS15690	COG0857	belongs to the CobB CobQ family
ACX60_RS15695	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX60_RS15695	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX60_RS15715	COG0740	serine-type endopeptidase activity
ACX60_RS15725	COG4774	siderophore transport
ACX60_RS15735	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACX60_RS15745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX60_RS15745	COG2813	Specifically methylates the guanine in position
ACX60_RS15845	COG0788	formyltetrahydrofolate deformylase activity
ACX60_RS15870	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX60_RS15870	COG4651	solute:proton antiporter activity
ACX60_RS15890	COG0724	RNA recognition motif
ACX60_RS15895	COG0210	DNA helicase
ACX60_RS15920	COG1733	regulation of RNA biosynthetic process
ACX60_RS15930	COG2900	Belongs to the SlyX family
ACX60_RS15935	COG0488	(ABC) transporter
ACX60_RS15940	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS15945	COG1560	Kdo2-lipid A biosynthetic process
ACX60_RS15955	COG1301	dicarboxylic acid transport
ACX60_RS16010	COG0473	3-isopropylmalate dehydrogenase activity
ACX60_RS16065	COG0583	DNA-binding transcription factor activity
ACX60_RS16075	COG0625	glutathione transferase activity
ACX60_RS16080	COG2378	regulation of single-species biofilm formation
ACX60_RS16085	COG0546	phosphoglycolate phosphatase activity
ACX60_RS16095	COG1530	ribonuclease E activity
ACX60_RS16100	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS16115	COG0583	DNA-binding transcription factor activity
ACX60_RS16120	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS16125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACX60_RS16135	COG0534	Mate efflux family protein
ACX60_RS16150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACX60_RS16175	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX60_RS16175	COG0493	'glutamate synthase
ACX60_RS16185	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACX60_RS16190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX60_RS16205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX60_RS16215	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACX60_RS16215	COG0644	oxidoreductase
ACX60_RS16225	COG0425	Belongs to the sulfur carrier protein TusA family
ACX60_RS16230	COG4535	Mg2 and Co2 transporter CorC
ACX60_RS16240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX60_RS16260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACX60_RS16265	COG0475	glutathione-regulated potassium exporter activity
ACX60_RS16265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX60_RS16280	COG0484	heat shock protein binding
ACX60_RS16285	COG0789	Transcriptional regulator
ACX60_RS16290	COG0598	Magnesium transport protein CorA
ACX60_RS16305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACX60_RS16310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX60_RS16315	COG1074	ATP-dependent DNA helicase activity
ACX60_RS16320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACX60_RS16340	COG2226	methyltransferase
ACX60_RS16360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACX60_RS16375	COG2111	Na H antiporter
ACX60_RS16375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX60_RS16380	COG1006	Multisubunit Na H antiporter MnhC subunit
ACX60_RS16385	COG0651	ATP synthesis coupled electron transport
ACX60_RS16390	COG1863	multisubunit Na H antiporter MnhE subunit
ACX60_RS16395	COG2212	antiporter activity
ACX60_RS16400	COG1320	monovalent cation:proton antiporter activity
ACX60_RS16415	COG0195	Participates in both transcription termination and antitermination
ACX60_RS16460	COG0237	dephospho-CoA kinase activity
ACX60_RS16470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX60_RS16485	COG0497	DNA recombination
ACX60_RS16495	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACX60_RS16525	COG2169	Transcriptional regulator
ACX60_RS16525	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX60_RS16530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACX60_RS16595	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACX60_RS16610	COG0326	Molecular chaperone. Has ATPase activity
ACX60_RS16625	COG2056	Na+-H+ antiporter family
ACX60_RS16630	COG0596	Alpha beta hydrolase
ACX60_RS16725	COG0546	phosphoglycolate phosphatase activity
ACX60_RS16730	COG1716	ATPase activity
ACX60_RS16775	COG0181	hydroxymethylbilane synthase activity
ACX60_RS16785	COG3275	phosphorelay sensor kinase activity
ACX60_RS16805	COG1538	Outer membrane efflux protein
ACX60_RS16810	COG0697	spore germination
ACX60_RS16835	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX60_RS16840	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACX60_RS16845	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX60_RS16850	COG0772	Belongs to the SEDS family
ACX60_RS16875	COG4974	Belongs to the 'phage' integrase family
ACX60_RS16880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_RS16890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACX60_RS16900	COG2197	response regulator
ACX60_RS16915	COG0793	Belongs to the peptidase S41A family
ACX60_RS16920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACX60_RS16925	COG0795	lipopolysaccharide-transporting ATPase activity
ACX60_RS16965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX60_RS16965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX60_RS16975	COG0004	ammonium transporteR
ACX60_RS16980	COG0347	Belongs to the P(II) protein family
ACX60_RS16990	COG0606	chelatase, subunit chli
ACX60_RS17000	COG0659	secondary active sulfate transmembrane transporter activity
ACX60_RS17005	COG0589	response to stress
ACX60_RS17050	COG0606	chelatase, subunit chli
ACX60_RS17055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX60_RS17065	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX60_RS17080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACX60_RS17095	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS17105	COG0477	Major facilitator Superfamily
ACX60_RS17110	COG2860	membrane
ACX60_RS17115	COG3012	SEC-C Motif Domain Protein
ACX60_RS17120	COG1253	flavin adenine dinucleotide binding
ACX60_RS17130	COG0477	Major facilitator Superfamily
ACX60_RS17140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX60_RS17175	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACX60_RS17185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACX60_RS17220	COG1309	transcriptional regulator
ACX60_RS17255	COG0758	DNA mediated transformation
ACX60_RS17265	COG0697	spore germination
ACX60_RS17270	COG1309	transcriptional regulator
ACX60_RS17285	COG0386	Belongs to the glutathione peroxidase family
ACX60_RS17355	COG1121	(ABC) transporter
ACX60_RS17360	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACX60_RS17365	COG1280	lysine exporter protein (LysE YggA)
ACX60_RS17370	COG2837	iron assimilation
ACX60_RS17375	COG0281	malic enzyme
ACX60_RS17420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX60_RS17420	COG0519	Catalyzes the synthesis of GMP from XMP
ACX60_RS17425	COG4399	Belongs to the UPF0754 family
ACX60_RS17430	COG2259	Doxx family
ACX60_RS17435	COG0586	Pfam SNARE associated Golgi protein
ACX60_RS17450	COG1192	Involved in chromosome partitioning
ACX60_RS17460	COG0271	Belongs to the BolA IbaG family
ACX60_RS17500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ACX60_RS17500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ACX60_RS17500	COG3321	synthase
ACX60_RS17500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACX60_RS17505	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS17510	COG0318	PFAM AMP-dependent synthetase and ligase
ACX60_RS17515	COG2197	response regulator
ACX60_RS17525	COG3916	Acyl-homoserine-lactone synthase
ACX60_RS17530	COG0477	Major facilitator Superfamily
ACX60_RS17535	COG1024	Enoyl-CoA hydratase
ACX60_RS17540	COG1024	Enoyl-CoA hydratase
ACX60_RS17545	COG1960	acyl-CoA dehydrogenase activity
ACX60_RS17550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX60_RS17570	COG1113	amino acid transport
ACX60_RS17575	COG1113	amino acid transport
ACX60_RS17580	COG0251	oxidation-reduction process
ACX60_RS17620	COG0564	pseudouridine synthase activity
ACX60_RS17690	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACX60_RS17705	COG1802	Transcriptional regulator
ACX60_RS17710	COG1448	Aminotransferase
ACX60_RS17715	COG0277	FAD linked oxidase domain protein
ACX60_RS17725	COG2186	Transcriptional regulator
ACX60_RS17735	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX60_RS17740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX60_RS17755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACX60_RS17760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACX60_RS17785	COG0438	transferase activity, transferring glycosyl groups
ACX60_RS17815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACX60_RS17845	COG0728	peptidoglycan biosynthetic process
ACX60_RS17850	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACX60_RS17905	COG0546	phosphoglycolate phosphatase activity
ACX60_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
ACX60_RS17930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_RS17935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX60_RS17940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX60_RS17945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX60_RS17950	COG1116	anion transmembrane transporter activity
ACX60_RS17955	COG1309	transcriptional regulator
ACX60_RS17960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACX60_RS17970	COG0196	riboflavin kinase activity
ACX60_RS17975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACX60_RS17985	COG1047	Peptidyl-prolyl cis-trans
ACX60_RS18025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACX60_RS18030	COG0657	acetylesterase activity
ACX60_RS18050	COG0583	DNA-binding transcription factor activity
ACX60_RS18080	COG2951	lytic endotransglycosylase activity
ACX60_RS18085	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACX60_RS18100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACX60_RS18110	COG0671	phosphoesterase, PA-phosphatase related
ACX60_RS18115	COG0861	Integral membrane protein TerC family
ACX60_RS18125	COG0754	glutathionylspermidine amidase activity
ACX60_RS18135	COG0402	S-adenosylhomocysteine deaminase activity
ACX60_RS18155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX60_RS18160	COG1230	cation diffusion facilitator family transporter
ACX60_RS18175	COG0706	membrane insertase activity
ACX60_RS18265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACX60_RS18450	COG0583	DNA-binding transcription factor activity
ACX60_RS18495	COG1194	a g-specific adenine glycosylase
ACX60_RS18660	COG1113	amino acid transport
ACX60_RS18665	COG1113	amino acid transport
ACX60_RS18885	COG2918	glutathione biosynthetic process