locus-tag	class	description
G6543_RS00010	COG0592	DNA-directed DNA polymerase activity
G6543_RS00020	COG0187	DNA topoisomerase II activity
G6543_RS00030	COG0586	Pfam SNARE associated Golgi protein
G6543_RS00060	COG0596	Alpha beta hydrolase
G6543_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G6543_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G6543_RS00110	COG1047	Peptidyl-prolyl cis-trans
G6543_RS00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G6543_RS00125	COG0196	riboflavin kinase activity
G6543_RS00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G6543_RS00140	COG1309	transcriptional regulator
G6543_RS00145	COG1116	anion transmembrane transporter activity
G6543_RS00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6543_RS00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6543_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6543_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6543_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS00190	COG0546	phosphoglycolate phosphatase activity
G6543_RS00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
G6543_RS00250	COG0728	peptidoglycan biosynthetic process
G6543_RS00275	COG1596	polysaccharide export
G6543_RS00280	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G6543_RS00290	COG1215	transferase activity, transferring glycosyl groups
G6543_RS00295	COG0438	transferase activity, transferring glycosyl groups
G6543_RS00315	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G6543_RS00320	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G6543_RS00335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6543_RS00345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6543_RS00355	COG2186	Transcriptional regulator
G6543_RS00365	COG0277	FAD linked oxidase domain protein
G6543_RS00370	COG1448	Aminotransferase
G6543_RS00380	COG1802	Transcriptional regulator
G6543_RS00395	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
G6543_RS00460	COG0564	pseudouridine synthase activity
G6543_RS00500	COG0251	oxidation-reduction process
G6543_RS00510	COG1113	amino acid transport
G6543_RS00515	COG1113	amino acid transport
G6543_RS00535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6543_RS00540	COG1960	acyl-CoA dehydrogenase activity
G6543_RS00545	COG1024	Enoyl-CoA hydratase
G6543_RS00550	COG1024	Enoyl-CoA hydratase
G6543_RS00555	COG0477	Major facilitator Superfamily
G6543_RS00560	COG3916	Acyl-homoserine-lactone synthase
G6543_RS00570	COG2197	response regulator
G6543_RS00580	COG1960	acyl-CoA dehydrogenase activity
G6543_RS00585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6543_RS00585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G6543_RS00585	COG3321	synthase
G6543_RS00585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
G6543_RS00595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6543_RS00610	COG2267	carboxylic ester hydrolase activity
G6543_RS00630	COG0271	Belongs to the BolA IbaG family
G6543_RS00640	COG1192	Involved in chromosome partitioning
G6543_RS00655	COG0586	Pfam SNARE associated Golgi protein
G6543_RS00660	COG2259	Doxx family
G6543_RS00665	COG4399	Belongs to the UPF0754 family
G6543_RS00670	COG0519	Catalyzes the synthesis of GMP from XMP
G6543_RS00670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6543_RS00715	COG0281	malic enzyme
G6543_RS00725	COG2837	iron assimilation
G6543_RS00730	COG1280	lysine exporter protein (LysE YggA)
G6543_RS00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G6543_RS00740	COG1121	(ABC) transporter
G6543_RS00805	COG0386	Belongs to the glutathione peroxidase family
G6543_RS00820	COG1309	transcriptional regulator
G6543_RS00825	COG0697	spore germination
G6543_RS00835	COG0758	DNA mediated transformation
G6543_RS00870	COG1309	transcriptional regulator
G6543_RS00905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G6543_RS00915	COG0655	NAD(P)H dehydrogenase (quinone) activity
G6543_RS00950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6543_RS00970	COG1253	flavin adenine dinucleotide binding
G6543_RS00980	COG2860	membrane
G6543_RS00985	COG0477	Major facilitator Superfamily
G6543_RS00995	COG0318	PFAM AMP-dependent synthetase and ligase
G6543_RS01010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G6543_RS01025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6543_RS01035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6543_RS01040	COG0606	chelatase, subunit chli
G6543_RS01080	COG0589	response to stress
G6543_RS01085	COG0659	secondary active sulfate transmembrane transporter activity
G6543_RS01105	COG1061	Type III restriction enzyme res subunit
G6543_RS01175	COG0606	chelatase, subunit chli
G6543_RS01185	COG0347	Belongs to the P(II) protein family
G6543_RS01190	COG0004	ammonium transporteR
G6543_RS01200	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6543_RS01200	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G6543_RS01240	COG0795	lipopolysaccharide-transporting ATPase activity
G6543_RS01245	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G6543_RS01250	COG0793	Belongs to the peptidase S41A family
G6543_RS01265	COG2197	response regulator
G6543_RS01275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G6543_RS01285	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6543_RS01290	COG4974	Belongs to the 'phage' integrase family
G6543_RS01315	COG0772	Belongs to the SEDS family
G6543_RS01320	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6543_RS01325	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G6543_RS01330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
G6543_RS01355	COG0697	spore germination
G6543_RS01360	COG1538	Outer membrane efflux protein
G6543_RS01380	COG3275	phosphorelay sensor kinase activity
G6543_RS01390	COG0181	hydroxymethylbilane synthase activity
G6543_RS01435	COG1716	ATPase activity
G6543_RS01440	COG0546	phosphoglycolate phosphatase activity
G6543_RS01535	COG0596	Alpha beta hydrolase
G6543_RS01540	COG2056	Na+-H+ antiporter family
G6543_RS01555	COG0326	Molecular chaperone. Has ATPase activity
G6543_RS01570	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
G6543_RS01635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G6543_RS01640	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6543_RS01640	COG2169	Transcriptional regulator
G6543_RS01670	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G6543_RS01680	COG0497	DNA recombination
G6543_RS01695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6543_RS01705	COG0237	dephospho-CoA kinase activity
G6543_RS01755	COG0195	Participates in both transcription termination and antitermination
G6543_RS01775	COG2212	antiporter activity
G6543_RS01785	COG0651	ATP synthesis coupled electron transport
G6543_RS01790	COG1006	Multisubunit Na H antiporter MnhC subunit
G6543_RS01795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6543_RS01795	COG2111	Na H antiporter
G6543_RS01810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G6543_RS01815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6543_RS01830	COG2226	methyltransferase
G6543_RS01850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G6543_RS01855	COG1074	ATP-dependent DNA helicase activity
G6543_RS01860	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6543_RS01880	COG0598	Magnesium transport protein CorA
G6543_RS01885	COG0789	Transcriptional regulator
G6543_RS01890	COG0484	heat shock protein binding
G6543_RS01900	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G6543_RS01905	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6543_RS01905	COG0475	glutathione-regulated potassium exporter activity
G6543_RS01910	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G6543_RS01935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6543_RS01945	COG4535	Mg2 and Co2 transporter CorC
G6543_RS01950	COG0425	Belongs to the sulfur carrier protein TusA family
G6543_RS01955	COG0644	oxidoreductase
G6543_RS01955	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G6543_RS01965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6543_RS01980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6543_RS01985	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G6543_RS02025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G6543_RS02040	COG0534	Mate efflux family protein
G6543_RS02050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G6543_RS02055	COG4221	oxidoreductase activity
G6543_RS02060	COG0583	DNA-binding transcription factor activity
G6543_RS02075	COG0318	PFAM AMP-dependent synthetase and ligase
G6543_RS02080	COG1530	ribonuclease E activity
G6543_RS02095	COG0546	phosphoglycolate phosphatase activity
G6543_RS02100	COG2378	regulation of single-species biofilm formation
G6543_RS02105	COG0625	glutathione transferase activity
G6543_RS02115	COG0583	DNA-binding transcription factor activity
G6543_RS02180	COG0473	3-isopropylmalate dehydrogenase activity
G6543_RS02235	COG1301	dicarboxylic acid transport
G6543_RS02245	COG1560	Kdo2-lipid A biosynthetic process
G6543_RS02250	COG1280	lysine exporter protein (LysE YggA)
G6543_RS02260	COG2900	Belongs to the SlyX family
G6543_RS02270	COG1733	regulation of RNA biosynthetic process
G6543_RS02295	COG0210	DNA helicase
G6543_RS02300	COG0724	RNA recognition motif
G6543_RS02320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6543_RS02320	COG4651	solute:proton antiporter activity
G6543_RS02345	COG0788	formyltetrahydrofolate deformylase activity
G6543_RS02445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6543_RS02445	COG2813	Specifically methylates the guanine in position
G6543_RS02455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G6543_RS02475	COG0740	serine-type endopeptidase activity
G6543_RS02495	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G6543_RS02495	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G6543_RS02500	COG0857	belongs to the CobB CobQ family
G6543_RS02500	COG0280	phosphate acetyltransferase
G6543_RS02505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G6543_RS02515	COG0800	Aldolase
G6543_RS02525	COG3265	gluconokinase activity
G6543_RS02530	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS02540	COG2267	carboxylic ester hydrolase activity
G6543_RS02555	COG0793	Belongs to the peptidase S41A family
G6543_RS02590	COG1426	Protein conserved in bacteria
G6543_RS02635	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G6543_RS02645	COG0318	PFAM AMP-dependent synthetase and ligase
G6543_RS02660	COG2986	histidine ammonia-lyase
G6543_RS02700	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS02705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G6543_RS02725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G6543_RS02735	COG1162	GTPase activity
G6543_RS02740	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G6543_RS02755	COG1538	Outer membrane efflux protein
G6543_RS02760	COG0577	efflux transmembrane transporter activity
G6543_RS02760	COG1136	(ABC) transporter
G6543_RS02765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS02790	COG0028	Belongs to the TPP enzyme family
G6543_RS02795	COG0440	acetolactate synthase activity
G6543_RS02825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G6543_RS02840	COG0084	hydrolase, TatD family'
G6543_RS02855	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G6543_RS02865	COG0583	DNA-binding transcription factor activity
G6543_RS02875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6543_RS02880	COG2814	Major facilitator Superfamily
G6543_RS02890	COG0697	spore germination
G6543_RS02920	COG3622	Belongs to the hyi family
G6543_RS02925	COG2084	Dehydrogenase
G6543_RS02930	COG1024	Enoyl-CoA hydratase
G6543_RS02935	COG2205	protein histidine kinase activity
G6543_RS02935	COG5002	protein histidine kinase activity
G6543_RS02935	COG0784	Response regulator, receiver
G6543_RS02955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6543_RS02965	COG3956	TIGRFAM MazG family protein
G6543_RS02970	COG1555	photosystem II stabilization
G6543_RS02975	COG0617	tRNA 3'-terminal CCA addition
G6543_RS02980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G6543_RS03000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6543_RS03005	COG3028	Belongs to the UPF0307 family
G6543_RS03010	COG0318	PFAM AMP-dependent synthetase and ligase
G6543_RS03025	COG0625	glutathione transferase activity
G6543_RS03030	COG1238	metal cluster binding
G6543_RS03070	COG0072	phenylalanine-tRNA ligase activity
G6543_RS03100	COG0248	Ppx GppA phosphatase
G6543_RS03110	COG0037	tRNA processing
G6543_RS03150	COG1764	response to oxidative stress
G6543_RS03155	COG1846	Transcriptional regulator
G6543_RS03165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6543_RS03225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G6543_RS03230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G6543_RS03235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G6543_RS03245	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G6543_RS03295	COG1214	PFAM Peptidase M22, glycoprotease
G6543_RS03320	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G6543_RS03325	COG0561	phosphatase activity
G6543_RS03335	COG2132	Multicopper oxidase
G6543_RS03340	COG3667	copper resistance
G6543_RS03355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G6543_RS03360	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
G6543_RS03365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G6543_RS03395	COG1063	alcohol dehydrogenase
G6543_RS03400	COG0583	DNA-binding transcription factor activity
G6543_RS03405	COG1960	acyl-CoA dehydrogenase activity
G6543_RS03410	COG2814	Major facilitator Superfamily
G6543_RS03415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
G6543_RS03425	COG1053	succinate dehydrogenase
G6543_RS03430	COG0583	DNA-binding transcription factor activity
G6543_RS03445	COG0583	DNA-binding transcription factor activity
G6543_RS03455	COG1473	amidohydrolase
G6543_RS03475	COG0583	DNA-binding transcription factor activity
G6543_RS03490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6543_RS03510	COG0384	phenazine biosynthesis protein PhzF
G6543_RS03530	COG4993	Dehydrogenase
G6543_RS03600	COG2205	protein histidine kinase activity
G6543_RS03610	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G6543_RS03630	COG0745	RESPONSE REGULATOR receiver
G6543_RS03635	COG2205	protein histidine kinase activity
G6543_RS03670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
G6543_RS03700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G6543_RS03705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G6543_RS03725	COG0583	DNA-binding transcription factor activity
G6543_RS03745	COG0668	transmembrane transport
G6543_RS03755	COG2081	HI0933 family
G6543_RS03760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G6543_RS03790	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6543_RS03790	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G6543_RS03800	COG0489	protein tyrosine kinase activity
G6543_RS03850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G6543_RS03860	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G6543_RS03875	COG0730	response to heat
G6543_RS03885	COG1196	nuclear chromosome segregation
G6543_RS03905	COG2223	nitrite transmembrane transporter activity
G6543_RS03910	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
G6543_RS03915	COG1877	trehalose-phosphatase activity
G6543_RS03920	COG2226	methyltransferase
G6543_RS03920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6543_RS03920	COG0596	Alpha beta hydrolase
G6543_RS03935	COG4106	trans-aconitate 2-methyltransferase activity
G6543_RS03950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G6543_RS03955	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
G6543_RS03960	COG0009	L-threonylcarbamoyladenylate synthase
G6543_RS03965	COG3101	peptidyl-lysine hydroxylation
G6543_RS03970	COG1399	metal-binding, possibly nucleic acid-binding protein
G6543_RS03995	COG1652	LysM domain
G6543_RS04000	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6543_RS04000	COG0352	thiamine-phosphate diphosphorylase activity
G6543_RS04000	COG0351	phosphomethylpyrimidine kinase
G6543_RS04010	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G6543_RS04040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6543_RS04070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G6543_RS04085	COG0358	DNA primase activity
G6543_RS04095	COG0564	pseudouridine synthase activity
G6543_RS04120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G6543_RS04140	COG0583	DNA-binding transcription factor activity
G6543_RS04145	COG0473	3-isopropylmalate dehydrogenase activity
G6543_RS04165	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS04185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G6543_RS04185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G6543_RS04245	COG0456	acetyltransferase
G6543_RS04255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G6543_RS04260	COG0492	ferredoxin-NADP+ reductase activity
G6543_RS04265	COG1674	ftsk spoiiie
G6543_RS04265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G6543_RS04270	COG1280	lysine exporter protein (LysE YggA)
G6543_RS04295	COG2894	cell division
G6543_RS04310	COG0204	Acyl-transferase
G6543_RS04315	COG2885	chlorophyll binding
G6543_RS04320	COG0210	DNA helicase
G6543_RS04330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G6543_RS04345	COG0121	glutamine amidotransferase
G6543_RS04365	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G6543_RS04370	COG0735	belongs to the Fur family
G6543_RS04395	COG0420	3'-5' exonuclease activity
G6543_RS04415	COG1090	epimerase
G6543_RS04430	COG2050	protein possibly involved in aromatic compounds catabolism
G6543_RS04440	COG2814	Major facilitator Superfamily
G6543_RS04445	COG0405	Gamma-glutamyltransferase
G6543_RS04480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6543_RS04580	COG3328	transposase activity
G6543_RS04600	COG1484	DNA-dependent DNA replication
G6543_RS04825	COG2026	Addiction module toxin, RelE StbE family
G6543_RS04870	COG0592	DNA-directed DNA polymerase activity
G6543_RS04955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G6543_RS05010	COG0477	Major facilitator Superfamily
G6543_RS05015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6543_RS05040	COG0531	amino acid
G6543_RS05045	COG2040	homocysteine
G6543_RS05070	COG1309	transcriptional regulator
G6543_RS05075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6543_RS05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6543_RS05090	COG1607	acyl-coa hydrolase
G6543_RS05100	COG0523	cobalamin synthesis protein
G6543_RS05110	COG4681	YaeQ
G6543_RS05120	COG0726	polysaccharide deacetylase
G6543_RS05120	COG1649	PFAM Uncharacterised BCR, COG1649
G6543_RS05125	COG1215	transferase activity, transferring glycosyl groups
G6543_RS05135	COG1024	Enoyl-CoA hydratase
G6543_RS05150	COG1414	Transcriptional regulator
G6543_RS05170	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS05180	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6543_RS05185	COG2271	Major facilitator Superfamily
G6543_RS05195	COG2267	carboxylic ester hydrolase activity
G6543_RS05200	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS05215	COG0028	Belongs to the TPP enzyme family
G6543_RS05225	COG0477	Major facilitator Superfamily
G6543_RS05230	COG0242	peptide deformylase activity
G6543_RS05235	COG2066	Belongs to the glutaminase family
G6543_RS05240	COG2207	Transcriptional regulator
G6543_RS05245	COG2223	nitrite transmembrane transporter activity
G6543_RS05260	COG0583	DNA-binding transcription factor activity
G6543_RS05265	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS05270	COG2271	Major facilitator Superfamily
G6543_RS05275	COG3959	Transketolase, thiamine diphosphate binding domain
G6543_RS05280	COG3958	Transketolase
G6543_RS05290	COG0306	phosphate transporter
G6543_RS05310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G6543_RS05355	COG4181	ATPase activity
G6543_RS05360	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G6543_RS05385	COG0583	DNA-binding transcription factor activity
G6543_RS05395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6543_RS05400	COG1773	rubredoxin
G6543_RS05450	COG2851	Citrate transporter
G6543_RS05455	COG1253	flavin adenine dinucleotide binding
G6543_RS05505	COG0830	nickel cation binding
G6543_RS05520	COG0742	ribosomal rna small subunit methyltransferase
G6543_RS05525	COG0768	penicillin binding
G6543_RS05550	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G6543_RS05555	COG2878	Part of a membrane complex involved in electron transport
G6543_RS05560	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6543_RS05570	COG3384	dioxygenase
G6543_RS05600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G6543_RS05925	COG0739	heme binding
G6543_RS05970	COG2194	sulfuric ester hydrolase activity
G6543_RS06005	COG0006	proline dipeptidase activity
G6543_RS06010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6543_RS06015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6543_RS06035	COG1279	arginine transmembrane transporter activity
G6543_RS06040	COG0583	DNA-binding transcription factor activity
G6543_RS06105	COG0482	sulfurtransferase activity
G6543_RS06125	COG3173	Aminoglycoside phosphotransferase
G6543_RS06135	COG2433	Pfam Transposase IS66
G6543_RS06175	COG1301	dicarboxylic acid transport
G6543_RS06185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6543_RS06190	COG2011	ABC-type metal ion transport system permease component
G6543_RS06195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6543_RS06200	COG1464	Belongs to the NlpA lipoprotein family
G6543_RS06205	COG0151	Belongs to the GarS family
G6543_RS06210	COG0138	bifunctional purine biosynthesis protein purh
G6543_RS06215	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G6543_RS06245	COG2308	Evidence 4 Homologs of previously reported genes of
G6543_RS06255	COG1305	Transglutaminase-like
G6543_RS06265	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G6543_RS06270	COG0305	Participates in initiation and elongation during chromosome replication
G6543_RS06295	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G6543_RS06305	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G6543_RS06310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G6543_RS06335	COG1649	PFAM Uncharacterised BCR, COG1649
G6543_RS06335	COG0726	polysaccharide deacetylase
G6543_RS06340	COG1215	transferase activity, transferring glycosyl groups
G6543_RS06345	COG3658	cytochrome
G6543_RS06355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6543_RS06370	COG0583	DNA-binding transcription factor activity
G6543_RS06390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6543_RS06395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6543_RS06410	COG1960	acyl-CoA dehydrogenase activity
G6543_RS06415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6543_RS06420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6543_RS06445	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
G6543_RS06450	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
G6543_RS06460	COG2205	protein histidine kinase activity
G6543_RS06465	COG0745	RESPONSE REGULATOR receiver
G6543_RS06470	COG0174	glutamine synthetase
G6543_RS06490	COG0729	surface antigen
G6543_RS06515	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6543_RS06520	COG2814	Major facilitator Superfamily
G6543_RS06535	COG0583	DNA-binding transcription factor activity
G6543_RS06550	COG1187	pseudouridine synthase activity
G6543_RS06570	COG0802	atpase or kinase
G6543_RS06575	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G6543_RS06585	COG1923	regulation of RNA biosynthetic process
G6543_RS06590	COG0697	spore germination
G6543_RS06605	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6543_RS06615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G6543_RS06620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G6543_RS06620	COG0519	Catalyzes the synthesis of GMP from XMP
G6543_RS06625	COG4302	ethanolamine ammonia-lyase activity
G6543_RS06630	COG4303	Ethanolamine ammonia lyase large subunit
G6543_RS06635	COG0531	amino acid
G6543_RS06655	COG1454	alcohol dehydrogenase
G6543_RS06660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G6543_RS06670	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
G6543_RS06690	COG0308	aminopeptidase N
G6543_RS06700	COG4221	oxidoreductase activity
G6543_RS06710	COG1605	Chorismate mutase
G6543_RS06725	COG1309	transcriptional regulator
G6543_RS06735	COG0668	transmembrane transport
G6543_RS06770	COG4773	Receptor
G6543_RS06790	COG0488	(ABC) transporter
G6543_RS06795	COG0589	response to stress
G6543_RS06820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
G6543_RS06830	COG3135	benzoate transporter
G6543_RS06835	COG1522	sequence-specific DNA binding
G6543_RS06845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G6543_RS06850	COG0583	DNA-binding transcription factor activity
G6543_RS06860	COG0183	Belongs to the thiolase family
G6543_RS06870	COG2030	dehydratase
G6543_RS06890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G6543_RS06900	COG0824	Thioesterase
G6543_RS06905	COG1454	alcohol dehydrogenase
G6543_RS06915	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G6543_RS06935	COG0069	glutamate synthase activity
G6543_RS06955	COG2814	Major facilitator Superfamily
G6543_RS06970	COG0511	ligase activity, forming carbon-carbon bonds
G6543_RS06990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
G6543_RS06990	COG1116	anion transmembrane transporter activity
G6543_RS06995	COG0745	RESPONSE REGULATOR receiver
G6543_RS07005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6543_RS07005	COG2146	nitrite reductase [NAD(P)H] activity
G6543_RS07010	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6543_RS07015	COG0243	molybdopterin cofactor binding
G6543_RS07025	COG0243	molybdopterin cofactor binding
G6543_RS07030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G6543_RS07045	COG0315	cyclic pyranopterin monophosphate synthase activity
G6543_RS07045	COG0521	Mo-molybdopterin cofactor biosynthetic process
G6543_RS07050	COG0303	'Molybdopterin
G6543_RS07060	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6543_RS07065	COG0697	spore germination
G6543_RS07085	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G6543_RS07090	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G6543_RS07145	COG2204	response regulator
G6543_RS07150	COG3852	Histidine kinase
G6543_RS07170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G6543_RS07175	COG0575	Belongs to the CDS family
G6543_RS07210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6543_RS07225	COG2137	regulation of response to DNA damage stimulus
G6543_RS07235	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
G6543_RS07240	COG1011	Hydrolase
G6543_RS07265	COG1522	sequence-specific DNA binding
G6543_RS07275	COG1113	amino acid transport
G6543_RS07290	COG0659	secondary active sulfate transmembrane transporter activity
G6543_RS07295	COG2135	peptidase activity
G6543_RS07310	COG5001	Diguanylate cyclase
G6543_RS07310	COG3300	MHYT domain
G6543_RS07330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6543_RS07330	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G6543_RS07330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G6543_RS07335	COG1105	Belongs to the carbohydrate kinase PfkB family
G6543_RS07345	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G6543_RS07345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G6543_RS07380	COG0024	Methionine aminopeptidase
G6543_RS07385	COG0583	DNA-binding transcription factor activity
G6543_RS07395	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G6543_RS07400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6543_RS07405	COG0517	IMP dehydrogenase activity
G6543_RS07405	COG0516	GMP reductase activity
G6543_RS07430	COG0552	protein localization to endoplasmic reticulum
G6543_RS07440	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
G6543_RS07455	COG4890	Cyd operon protein YbgT
G6543_RS07460	COG1294	oxidase, subunit
G6543_RS07475	COG1585	Membrane protein implicated in regulation of membrane protease activity
G6543_RS07485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G6543_RS07490	COG4774	siderophore transport
G6543_RS07505	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G6543_RS07510	COG0569	domain protein
G6543_RS07515	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G6543_RS07545	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G6543_RS07550	COG0542	response to heat
G6543_RS07575	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6543_RS07575	COG1902	pentaerythritol trinitrate reductase activity
G6543_RS07625	COG2323	membrane
G6543_RS07630	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G6543_RS07640	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G6543_RS07645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6543_RS07650	COG0183	Belongs to the thiolase family
G6543_RS07655	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G6543_RS07660	COG0596	Alpha beta hydrolase
G6543_RS07665	COG2271	Major facilitator Superfamily
G6543_RS07670	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6543_RS07675	COG3485	protocatechuate 3,4-dioxygenase
G6543_RS07680	COG3485	protocatechuate 3,4-dioxygenase
G6543_RS07685	COG0710	3-dehydroquinate dehydratase activity
G6543_RS07690	COG3420	alginic acid biosynthetic process
G6543_RS07695	COG3659	wide pore channel activity
G6543_RS07700	COG4993	Dehydrogenase
G6543_RS07710	COG2391	methyltransferase activity
G6543_RS07725	COG1414	Transcriptional regulator
G6543_RS07730	COG0583	DNA-binding transcription factor activity
G6543_RS07735	COG1960	acyl-CoA dehydrogenase activity
G6543_RS07760	COG2814	Major facilitator Superfamily
G6543_RS07770	COG0154	amidase activity
G6543_RS07790	COG4638	Rieske (2fe-2S)
G6543_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS07810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6543_RS07820	COG3733	amine oxidase
G6543_RS07830	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS07840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
G6543_RS07845	COG0183	Belongs to the thiolase family
G6543_RS07850	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6543_RS07855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G6543_RS07865	COG4829	muconolactone delta-isomerase
G6543_RS07870	COG4948	Mandelate Racemase Muconate Lactonizing
G6543_RS07875	COG0583	DNA-binding transcription factor activity
G6543_RS07885	COG2186	Transcriptional regulator
G6543_RS07905	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS07925	COG1960	acyl-CoA dehydrogenase activity
G6543_RS07935	COG3829	transcription factor binding
G6543_RS07945	COG3162	membrane
G6543_RS07960	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS07975	COG0753	catalase activity
G6543_RS07995	COG1846	Transcriptional regulator
G6543_RS08000	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6543_RS08000	COG1902	pentaerythritol trinitrate reductase activity
G6543_RS08010	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G6543_RS08040	COG1309	transcriptional regulator
G6543_RS08050	COG1335	isochorismatase
G6543_RS08055	COG0583	DNA-binding transcription factor activity
G6543_RS08065	COG0475	glutathione-regulated potassium exporter activity
G6543_RS08065	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G6543_RS08075	COG1473	amidohydrolase
G6543_RS08085	COG2831	hemolysin activation secretion protein
G6543_RS08090	COG3210	domain, Protein
G6543_RS08120	COG2188	Transcriptional regulator
G6543_RS08135	COG0583	DNA-binding transcription factor activity
G6543_RS08165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6543_RS08185	COG1566	PFAM secretion protein HlyD family protein
G6543_RS08200	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS08205	COG0129	dihydroxy-acid dehydratase activity
G6543_RS08215	COG0583	DNA-binding transcription factor activity
G6543_RS08220	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G6543_RS08230	COG2084	Dehydrogenase
G6543_RS08235	COG2207	Transcriptional regulator
G6543_RS08250	COG1064	alcohol dehydrogenase
G6543_RS08265	COG1120	ATPase activity
G6543_RS08285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G6543_RS08400	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G6543_RS08450	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS08465	COG2207	Transcriptional regulator
G6543_RS08475	COG2205	protein histidine kinase activity
G6543_RS08480	COG0745	RESPONSE REGULATOR receiver
G6543_RS08485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS08490	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6543_RS08495	COG1538	Outer membrane efflux protein
G6543_RS08505	COG2072	flavoprotein involved in K transport
G6543_RS08525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6543_RS08545	COG3539	Fimbrial protein
G6543_RS08575	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
G6543_RS08585	COG0753	catalase activity
G6543_RS08600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6543_RS08665	COG1535	isochorismatase
G6543_RS08665	COG3433	isochorismatase activity
G6543_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS08675	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G6543_RS08680	COG4149	molybdate abc transporter
G6543_RS08685	COG0725	ABC transporter, periplasmic molybdate-binding protein
G6543_RS08695	COG4638	Rieske (2fe-2S)
G6543_RS08700	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G6543_RS08705	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6543_RS08705	COG0543	2 iron, 2 sulfur cluster binding
G6543_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS08745	COG2207	Transcriptional regulator
G6543_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS08760	COG2610	gluconate transmembrane transporter activity
G6543_RS08770	COG0583	DNA-binding transcription factor activity
G6543_RS08780	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6543_RS08785	COG2031	fatty acid transporter
G6543_RS08790	COG0183	Belongs to the thiolase family
G6543_RS08795	COG0583	DNA-binding transcription factor activity
G6543_RS08800	COG0583	DNA-binding transcription factor activity
G6543_RS08815	COG1027	Aspartate ammonia-lyase
G6543_RS08825	COG0477	Major facilitator Superfamily
G6543_RS08845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6543_RS08850	COG4521	taurine ABC transporter
G6543_RS08865	COG2188	Transcriptional regulator
G6543_RS08875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G6543_RS08880	COG1733	regulation of RNA biosynthetic process
G6543_RS08885	COG3708	Transcriptional regulator
G6543_RS08885	COG2207	Transcriptional regulator
G6543_RS08900	COG0730	response to heat
G6543_RS08910	COG3453	Protein conserved in bacteria
G6543_RS08910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6543_RS08920	COG3781	membrane
G6543_RS08925	COG1063	alcohol dehydrogenase
G6543_RS08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6543_RS08940	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6543_RS08945	COG0022	dehydrogenase e1 component
G6543_RS08950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G6543_RS08955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6543_RS08970	COG3706	GGDEF domain
G6543_RS08985	COG0133	tryptophan synthase activity
G6543_RS08995	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6543_RS09030	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G6543_RS09055	COG2226	methyltransferase
G6543_RS09110	COG0842	Transport permease protein
G6543_RS09115	COG0842	Transport permease protein
G6543_RS09120	COG1131	(ABC) transporter
G6543_RS09135	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G6543_RS09140	COG4773	Receptor
G6543_RS09160	COG0730	response to heat
G6543_RS09165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G6543_RS09185	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
G6543_RS09240	COG4264	IucA IucC family
G6543_RS09245	COG4264	IucA IucC family
G6543_RS09265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G6543_RS09280	COG1960	acyl-CoA dehydrogenase activity
G6543_RS09285	COG1960	acyl-CoA dehydrogenase activity
G6543_RS09290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G6543_RS09295	COG2207	Transcriptional regulator
G6543_RS09300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6543_RS09305	COG0776	regulation of translation
G6543_RS09330	COG0822	iron-sulfur transferase activity
G6543_RS09335	COG0316	Belongs to the HesB IscA family
G6543_RS09365	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G6543_RS09385	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G6543_RS09390	COG0702	epimerase
G6543_RS09425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G6543_RS09435	COG0339	signal peptide processing
G6543_RS09485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G6543_RS09490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G6543_RS09520	COG0776	regulation of translation
G6543_RS09585	COG0084	hydrolase, TatD family'
G6543_RS09610	COG1132	(ABC) transporter
G6543_RS09620	COG0811	peptide transport
G6543_RS09625	COG1475	DNA binding
G6543_RS09630	COG1192	Involved in chromosome partitioning
G6543_RS09640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G6543_RS09655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G6543_RS09660	COG0191	fructose-bisphosphate aldolase activity
G6543_RS09680	COG0424	maF-like protein
G6543_RS09685	COG2850	peptidyl-arginine hydroxylation
G6543_RS09695	COG0640	Transcriptional regulator
G6543_RS09705	COG3619	membrane
G6543_RS09710	COG3122	Protein conserved in bacteria
G6543_RS09715	COG1132	(ABC) transporter
G6543_RS09735	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G6543_RS09740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6543_RS09750	COG0506	proline dehydrogenase activity
G6543_RS09750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G6543_RS09750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G6543_RS09755	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
G6543_RS09770	COG3698	Phosphodiester glycosidase
G6543_RS09780	COG2353	YceI-like domain
G6543_RS09790	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G6543_RS09835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G6543_RS09835	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G6543_RS09860	COG3539	Fimbrial protein
G6543_RS09865	COG3121	Chaperone
G6543_RS09890	COG0697	spore germination
G6543_RS09900	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G6543_RS09910	COG0583	DNA-binding transcription factor activity
G6543_RS09930	COG1309	transcriptional regulator
G6543_RS09945	COG1522	sequence-specific DNA binding
G6543_RS09955	COG1126	abc transporter atp-binding protein
G6543_RS09965	COG0765	amino acid transport
G6543_RS09995	COG1464	Belongs to the NlpA lipoprotein family
G6543_RS10005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G6543_RS10010	COG2011	ABC-type metal ion transport system permease component
G6543_RS10015	COG0012	GTP binding
G6543_RS10040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G6543_RS10080	COG0386	Belongs to the glutathione peroxidase family
G6543_RS10090	COG0436	Aminotransferase
G6543_RS10130	COG3634	alkyl hydroperoxide reductase activity
G6543_RS10145	COG0583	DNA-binding transcription factor activity
G6543_RS10150	COG0798	PFAM Bile acid sodium symporter
G6543_RS10155	COG0640	Transcriptional regulator
G6543_RS10170	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
G6543_RS10180	COG0583	DNA-binding transcription factor activity
G6543_RS10190	COG1953	Uracil, thiamine, allantoin
G6543_RS10200	COG2175	clavaminate synthase activity
G6543_RS10205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
G6543_RS10210	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
G6543_RS10215	COG4521	taurine ABC transporter
G6543_RS10225	COG0477	Major facilitator Superfamily
G6543_RS10245	COG1271	oxidase subunit
G6543_RS10250	COG1294	oxidase, subunit
G6543_RS10260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6543_RS10280	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G6543_RS10300	COG3052	prosthetic group binding
G6543_RS10305	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
G6543_RS10315	COG2814	Major facilitator Superfamily
G6543_RS10335	COG1346	cytolysis
G6543_RS10345	COG0583	DNA-binding transcription factor activity
G6543_RS10350	COG0625	glutathione transferase activity
G6543_RS10355	COG0625	glutathione transferase activity
G6543_RS10360	COG0583	DNA-binding transcription factor activity
G6543_RS10375	COG1045	serine acetyltransferase
G6543_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G6543_RS10385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G6543_RS10395	COG1280	lysine exporter protein (LysE YggA)
G6543_RS10410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6543_RS10415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6543_RS10420	COG1126	abc transporter atp-binding protein
G6543_RS10425	COG0765	amino acid transport
G6543_RS10430	COG0765	amino acid transport
G6543_RS10450	COG2205	protein histidine kinase activity
G6543_RS10450	COG0784	Response regulator, receiver
G6543_RS10470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G6543_RS10490	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS10540	COG0583	DNA-binding transcription factor activity
G6543_RS10560	COG0318	PFAM AMP-dependent synthetase and ligase
G6543_RS10565	COG1309	transcriptional regulator
G6543_RS10570	COG1960	acyl-CoA dehydrogenase activity
G6543_RS10575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6543_RS10580	COG1024	Enoyl-CoA hydratase
G6543_RS10585	COG4770	biotin carboxylase activity
G6543_RS10595	COG0583	DNA-binding transcription factor activity
G6543_RS10610	COG1960	acyl-CoA dehydrogenase activity
G6543_RS10620	COG2814	Major facilitator Superfamily
G6543_RS10630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
G6543_RS10635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
G6543_RS10640	COG2814	Major facilitator Superfamily
G6543_RS10645	COG1960	acyl-CoA dehydrogenase activity
G6543_RS10650	COG1024	Enoyl-CoA hydratase
G6543_RS10655	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS10660	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6543_RS10665	COG0183	Belongs to the thiolase family
G6543_RS10675	COG2814	Major facilitator Superfamily
G6543_RS10685	COG1024	Enoyl-CoA hydratase
G6543_RS10700	COG1960	acyl-CoA dehydrogenase activity
G6543_RS10705	COG2814	Major facilitator Superfamily
G6543_RS10710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G6543_RS10715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
G6543_RS10730	COG3842	ATPase activity
G6543_RS10735	COG1840	ABC-type Fe3 transport system, periplasmic component
G6543_RS10745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6543_RS10750	COG1414	Transcriptional regulator
G6543_RS10760	COG0583	DNA-binding transcription factor activity
G6543_RS10765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G6543_RS10770	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS10780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
G6543_RS10790	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS10795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G6543_RS10800	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6543_RS10805	COG2267	carboxylic ester hydrolase activity
G6543_RS10825	COG3038	cytochrome b561
G6543_RS10830	COG0753	catalase activity
G6543_RS10865	COG2050	protein possibly involved in aromatic compounds catabolism
G6543_RS10875	COG3327	negative regulation of DNA-templated transcription, initiation
G6543_RS10880	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
G6543_RS10885	COG0183	Belongs to the thiolase family
G6543_RS10890	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6543_RS10895	COG1024	Enoyl-CoA hydratase
G6543_RS10900	COG1024	Enoyl-CoA hydratase
G6543_RS10905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6543_RS10910	COG2151	metal-sulfur cluster biosynthetic enzyme
G6543_RS10915	COG3396	Phenylacetate-CoA oxygenase
G6543_RS10920	COG3460	Phenylacetate-CoA oxygenase
G6543_RS10925	COG3396	Phenylacetate-CoA oxygenase
G6543_RS10930	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS10930	COG2030	dehydratase
G6543_RS10935	COG1760	l-serine dehydratase
G6543_RS10940	COG0531	amino acid
G6543_RS10945	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS10960	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6543_RS10970	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6543_RS10990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6543_RS11000	COG0789	Transcriptional regulator
G6543_RS11015	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G6543_RS11030	COG2807	transmembrane transport
G6543_RS11035	COG0590	tRNA wobble adenosine to inosine editing
G6543_RS11150	COG1116	anion transmembrane transporter activity
G6543_RS11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G6543_RS11165	COG0864	Transcriptional regulator
G6543_RS11185	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6543_RS11190	COG0439	Biotin carboxylase
G6543_RS11205	COG1063	alcohol dehydrogenase
G6543_RS11215	COG1309	transcriptional regulator
G6543_RS11235	COG0038	chloride channel
G6543_RS11240	COG4770	biotin carboxylase activity
G6543_RS11260	COG1914	H( )-stimulated, divalent metal cation uptake system
G6543_RS11265	COG0583	DNA-binding transcription factor activity
G6543_RS11280	COG3209	COG3209 Rhs family protein
G6543_RS11285	COG3501	Rhs element vgr protein
G6543_RS11315	COG1250	3-hydroxyacyl-CoA dehydrogenase
G6543_RS11335	COG2814	Major facilitator Superfamily
G6543_RS11345	COG1560	Kdo2-lipid A biosynthetic process
G6543_RS11355	COG5006	permease, DMT superfamily
G6543_RS11360	COG1522	sequence-specific DNA binding
G6543_RS11375	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G6543_RS11385	COG4122	O-methyltransferase activity
G6543_RS11415	COG1538	Outer membrane efflux protein
G6543_RS11420	COG1137	ATPase activity
G6543_RS11425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G6543_RS11435	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G6543_RS11440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G6543_RS11440	COG0517	IMP dehydrogenase activity
G6543_RS11480	COG2814	Major facilitator Superfamily
G6543_RS11515	COG1278	Cold shock
G6543_RS11520	COG1280	lysine exporter protein (LysE YggA)
G6543_RS11555	COG1570	exodeoxyribonuclease VII activity
G6543_RS11605	COG0583	DNA-binding transcription factor activity
G6543_RS11610	COG4638	Rieske (2fe-2S)
G6543_RS11615	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
G6543_RS11620	COG0633	Ferredoxin
G6543_RS11620	COG0543	2 iron, 2 sulfur cluster binding
G6543_RS11625	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS11630	COG3135	benzoate transporter
G6543_RS11635	COG2814	Major facilitator Superfamily
G6543_RS11650	COG1643	Atp-dependent helicase
G6543_RS11655	COG0450	alkyl hydroperoxide reductase
G6543_RS11665	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G6543_RS11675	COG3634	alkyl hydroperoxide reductase activity
G6543_RS11695	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G6543_RS11700	COG0625	glutathione transferase activity
G6543_RS11710	COG2885	chlorophyll binding
G6543_RS11745	COG0542	response to heat
G6543_RS11765	COG1765	OsmC-like protein
G6543_RS11780	COG0667	Aldo Keto reductase
G6543_RS11795	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G6543_RS11805	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G6543_RS11815	COG0527	aspartate kinase activity
G6543_RS11825	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G6543_RS11835	COG3038	cytochrome b561
G6543_RS11840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G6543_RS11845	COG2252	PERMEase
G6543_RS11855	COG2072	flavoprotein involved in K transport
G6543_RS11870	COG1741	Belongs to the pirin family
G6543_RS11875	COG1309	transcriptional regulator
G6543_RS11885	COG0300	oxidoreductase activity
G6543_RS11905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G6543_RS11935	COG1113	amino acid transport
G6543_RS11955	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS11975	COG0531	amino acid
G6543_RS11985	COG1113	amino acid transport
G6543_RS12025	COG3209	COG3209 Rhs family protein
G6543_RS12030	COG3501	Rhs element vgr protein
G6543_RS12055	COG4269	membrane
G6543_RS12070	COG0446	pyridine nucleotide-disulphide oxidoreductase
G6543_RS12070	COG1902	pentaerythritol trinitrate reductase activity
G6543_RS12080	COG5001	Diguanylate cyclase
G6543_RS12080	COG2203	Gaf domain
G6543_RS12080	COG4251	negative regulation of phosphorylation
G6543_RS12080	COG3706	GGDEF domain
G6543_RS12090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6543_RS12110	COG4172	Belongs to the ABC transporter superfamily
G6543_RS12115	COG4239	(ABC) transporter, permease
G6543_RS12120	COG4174	ABC transporter (Permease)
G6543_RS12130	COG0741	lytic transglycosylase activity
G6543_RS12130	COG0741	lytic transglycosylase activity
G6543_RS12130	COG1388	LysM domain
G6543_RS12130	COG1388	LysM domain
G6543_RS12135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G6543_RS12255	COG1610	YqeY-like protein
G6543_RS12260	COG4783	chaperone-mediated protein folding
G6543_RS12285	COG1286	toxin biosynthetic process
G6543_RS12315	COG0778	Nitroreductase
G6543_RS12325	COG0513	Belongs to the DEAD box helicase family
G6543_RS12345	COG2363	Small membrane protein
G6543_RS12375	COG1234	tRNA 3'-trailer cleavage
G6543_RS12380	COG2195	Cleaves the N-terminal amino acid of tripeptides
G6543_RS12390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G6543_RS12400	COG2819	hydrolase of the alpha beta superfamily
G6543_RS12405	COG1960	acyl-CoA dehydrogenase activity
G6543_RS12410	COG1301	dicarboxylic acid transport
G6543_RS12415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G6543_RS12420	COG3139	Protein of unknown function (DUF1315)
G6543_RS12425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G6543_RS12430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G6543_RS12440	COG0494	nUDIX hydrolase
G6543_RS12450	COG0642	Histidine kinase
G6543_RS12455	COG0745	RESPONSE REGULATOR receiver
G6543_RS12475	COG1720	tRNA m6t6A37 methyltransferase activity
G6543_RS12490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6543_RS12500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G6543_RS12510	COG4598	ABC transporter
G6543_RS12515	COG4160	amino acid transport
G6543_RS12520	COG4215	(ABC) transporter
G6543_RS12535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS12580	COG1131	(ABC) transporter
G6543_RS12585	COG0842	Transport permease protein
G6543_RS12600	COG0772	Belongs to the SEDS family
G6543_RS12605	COG2951	lytic endotransglycosylase activity
G6543_RS12630	COG2207	Transcriptional regulator
G6543_RS12645	COG0052	Belongs to the universal ribosomal protein uS2 family
G6543_RS12650	COG0024	Methionine aminopeptidase
G6543_RS12660	COG2223	nitrite transmembrane transporter activity
G6543_RS12670	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6543_RS12675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G6543_RS12680	COG1960	acyl-CoA dehydrogenase activity
G6543_RS12695	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G6543_RS12700	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G6543_RS12705	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G6543_RS12725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6543_RS12730	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G6543_RS12735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G6543_RS12770	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G6543_RS12780	COG0174	glutamine synthetase
G6543_RS12785	COG3104	oligopeptide transport
G6543_RS12795	COG0512	Glutamine amidotransferase of anthranilate synthase
G6543_RS12800	COG0308	aminopeptidase N
G6543_RS12830	COG1529	Aldehyde oxidase and xanthine dehydrogenase
G6543_RS12865	COG3739	integral membrane protein
G6543_RS12880	COG1169	isochorismate synthase
G6543_RS12890	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
G6543_RS12900	COG1132	(ABC) transporter
G6543_RS12915	COG3433	isochorismatase activity
G6543_RS12915	COG1535	isochorismatase
G6543_RS12920	COG1021	2,3-dihydroxybenzoate-AMP ligase
G6543_RS12925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6543_RS12935	COG4774	siderophore transport
G6543_RS12940	COG4607	ABC-type enterochelin transport system periplasmic component
G6543_RS12945	COG4604	ABC transporter, ATP-binding protein
G6543_RS12950	COG4605	iron ion homeostasis
G6543_RS12955	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G6543_RS12960	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6543_RS12975	COG2964	Protein conserved in bacteria
G6543_RS12985	COG1741	Belongs to the pirin family
G6543_RS13005	COG1309	transcriptional regulator
G6543_RS13015	COG4948	Mandelate Racemase Muconate Lactonizing
G6543_RS13020	COG2814	Major facilitator Superfamily
G6543_RS13055	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G6543_RS13055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G6543_RS13060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6543_RS13065	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS13075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6543_RS13080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6543_RS13085	COG0583	DNA-binding transcription factor activity
G6543_RS13090	COG1113	amino acid transport
G6543_RS13110	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
G6543_RS13110	COG2508	Transcriptional regulator
G6543_RS13145	COG2879	small protein
G6543_RS13150	COG1966	Carbon starvation protein
G6543_RS13195	COG1067	ATP-dependent peptidase activity
G6543_RS13200	COG0583	DNA-binding transcription factor activity
G6543_RS13225	COG1686	Belongs to the peptidase S11 family
G6543_RS13230	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G6543_RS13265	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G6543_RS13275	COG0573	inorganic phosphate transmembrane transporter activity
G6543_RS13280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G6543_RS13285	COG1113	amino acid transport
G6543_RS13290	COG3961	Belongs to the TPP enzyme family
G6543_RS13295	COG1522	sequence-specific DNA binding
G6543_RS13305	COG0076	glutamate decarboxylase activity
G6543_RS13310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6543_RS13320	COG1309	transcriptional regulator
G6543_RS13335	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6543_RS13370	COG0352	thiamine-phosphate diphosphorylase activity
G6543_RS13395	COG0612	Peptidase, M16
G6543_RS13410	COG0583	DNA-binding transcription factor activity
G6543_RS13415	COG0477	Major facilitator Superfamily
G6543_RS13440	COG1187	pseudouridine synthase activity
G6543_RS13455	COG1686	Belongs to the peptidase S11 family
G6543_RS13460	COG1252	NADH dehydrogenase
G6543_RS13470	COG0415	Belongs to the DNA photolyase family
G6543_RS13485	COG1215	transferase activity, transferring glycosyl groups
G6543_RS13515	COG2070	2-Nitropropane dioxygenase
G6543_RS13570	COG0556	nucleotide-excision repair
G6543_RS13590	COG0436	Aminotransferase
G6543_RS13620	COG4221	oxidoreductase activity
G6543_RS13630	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G6543_RS13635	COG1381	Involved in DNA repair and RecF pathway recombination
G6543_RS13645	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G6543_RS13660	COG0681	Belongs to the peptidase S26 family
G6543_RS13675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G6543_RS13695	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G6543_RS13705	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G6543_RS13715	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G6543_RS13720	COG4208	sulfate ABC transporter
G6543_RS13725	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G6543_RS13730	COG0583	DNA-binding transcription factor activity
G6543_RS13735	COG4625	pathogenesis
G6543_RS13750	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G6543_RS13765	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G6543_RS13775	COG1051	belongs to the nudix hydrolase family
G6543_RS13775	COG1056	cytidyltransferase-related domain
G6543_RS13780	COG1024	Enoyl-CoA hydratase
G6543_RS13790	COG2814	Major facilitator Superfamily
G6543_RS13795	COG0047	phosphoribosylformylglycinamidine synthase activity
G6543_RS13795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G6543_RS13815	COG1473	amidohydrolase
G6543_RS13820	COG0824	Thioesterase
G6543_RS13840	COG0823	Involved in the tonB-independent uptake of proteins
G6543_RS13860	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G6543_RS13895	COG0628	permease
G6543_RS13905	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G6543_RS13910	COG0596	Alpha beta hydrolase
G6543_RS13915	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G6543_RS13915	COG0616	signal peptide processing
G6543_RS13925	COG0658	competence protein
G6543_RS13925	COG2333	competence protein COMEC
G6543_RS13930	COG1136	(ABC) transporter
G6543_RS13935	COG4591	ABC-type transport system involved in lipoprotein release permease component
G6543_RS13970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS13990	COG0463	Glycosyl transferase, family 2
G6543_RS14020	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
G6543_RS14025	COG1280	lysine exporter protein (LysE YggA)
G6543_RS14035	COG0019	diaminopimelate decarboxylase activity
G6543_RS14045	COG1113	amino acid transport
G6543_RS14060	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
G6543_RS14070	COG3339	Conserved Protein
G6543_RS14075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G6543_RS14080	COG0243	molybdopterin cofactor binding
G6543_RS14085	COG1929	Belongs to the glycerate kinase type-1 family
G6543_RS14100	COG0778	Nitroreductase
G6543_RS14125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6543_RS14140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G6543_RS14160	COG0741	lytic transglycosylase activity
G6543_RS14180	COG0584	glycerophosphoryl diester phosphodiesterase
G6543_RS14185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G6543_RS14215	COG1597	lipid kinase activity
G6543_RS14230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G6543_RS14235	COG0477	Major facilitator Superfamily
G6543_RS14290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G6543_RS14315	COG0505	Belongs to the CarA family
G6543_RS14335	COG0589	response to stress
G6543_RS14350	COG2843	Capsule synthesis protein
G6543_RS14380	COG2321	neutral zinc metallopeptidase
G6543_RS14385	COG2354	Protein conserved in bacteria
G6543_RS14405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G6543_RS14430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G6543_RS14435	COG1053	succinate dehydrogenase
G6543_RS14440	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G6543_RS14445	COG2009	succinate dehydrogenase
G6543_RS14485	COG2921	Belongs to the UPF0250 family
G6543_RS14490	COG0321	lipoyl(octanoyl) transferase activity
G6543_RS14505	COG0531	amino acid
G6543_RS14515	COG1733	regulation of RNA biosynthetic process
G6543_RS14520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G6543_RS14525	COG1648	precorrin-2 dehydrogenase activity
G6543_RS14525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G6543_RS14540	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G6543_RS14570	COG0671	phosphoesterase, PA-phosphatase related
G6543_RS14575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS14585	COG1538	Outer membrane efflux protein
G6543_RS14590	COG0393	Putative heavy-metal-binding
G6543_RS14595	COG0393	Putative heavy-metal-binding
G6543_RS14605	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS14615	COG0525	valine-tRNA ligase activity
G6543_RS14635	COG0583	DNA-binding transcription factor activity
G6543_RS14640	COG0004	ammonium transporteR
G6543_RS14650	COG0642	Histidine kinase
G6543_RS14655	COG0745	RESPONSE REGULATOR receiver
G6543_RS14660	COG2194	sulfuric ester hydrolase activity
G6543_RS14680	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6543_RS14695	COG2315	Protein conserved in bacteria
G6543_RS14700	COG0142	geranyltranstransferase activity
G6543_RS14705	COG2828	Protein conserved in bacteria
G6543_RS14710	COG1113	amino acid transport
G6543_RS14730	COG2207	Transcriptional regulator
G6543_RS14755	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6543_RS14765	COG0560	Phosphoserine phosphatase
G6543_RS14775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G6543_RS14785	COG1530	ribonuclease E activity
G6543_RS14790	COG0424	maF-like protein
G6543_RS14795	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G6543_RS14800	COG1792	Involved in formation and maintenance of cell shape
G6543_RS14805	COG1077	Cell shape determining protein MreB Mrl
G6543_RS14810	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6543_RS14820	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
G6543_RS14850	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
G6543_RS14855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
G6543_RS14860	COG1752	Esterase of the alpha-beta hydrolase superfamily
G6543_RS14865	COG1115	amino acid carrier protein
G6543_RS14885	COG2814	Major facilitator Superfamily
G6543_RS14890	COG1289	transmembrane transporter activity
G6543_RS14900	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G6543_RS14940	COG1376	ErfK ybiS ycfS ynhG family protein
G6543_RS14945	COG2832	Protein of unknown function (DUF454)
G6543_RS14955	COG5510	response to toxic substance
G6543_RS14975	COG0840	transmembrane signaling receptor activity
G6543_RS15015	COG3422	double-strand break repair
G6543_RS15020	COG2824	Alkylphosphonate utilization operon protein PhnA
G6543_RS15025	COG3189	MarR family transcriptional regulator
G6543_RS15035	COG0354	folic acid binding
G6543_RS15040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6543_RS15050	COG0679	Auxin Efflux Carrier
G6543_RS15055	COG1902	pentaerythritol trinitrate reductase activity
G6543_RS15070	COG4772	TonB-dependent receptor
G6543_RS15075	COG2094	Belongs to the DNA glycosylase MPG family
G6543_RS15105	COG2233	PERMEase
G6543_RS15115	COG0833	amino acid
G6543_RS15120	COG1690	Belongs to the RtcB family
G6543_RS15130	COG2885	chlorophyll binding
G6543_RS15130	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
G6543_RS15140	COG0183	Belongs to the thiolase family
G6543_RS15160	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G6543_RS15180	COG2207	Transcriptional regulator
G6543_RS15185	COG0183	Belongs to the thiolase family
G6543_RS15215	COG1272	protein, Hemolysin III
G6543_RS15220	COG0477	Major facilitator Superfamily
G6543_RS15235	COG0450	alkyl hydroperoxide reductase
G6543_RS15255	COG0285	dihydrofolate synthase activity
G6543_RS15305	COG2096	Adenosyltransferase
G6543_RS15325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G6543_RS15330	COG0745	RESPONSE REGULATOR receiver
G6543_RS15335	COG2205	protein histidine kinase activity
G6543_RS15345	COG1960	acyl-CoA dehydrogenase activity
G6543_RS15350	COG1960	acyl-CoA dehydrogenase activity
G6543_RS15355	COG0583	DNA-binding transcription factor activity
G6543_RS15360	COG0625	glutathione transferase activity
G6543_RS15425	COG0438	transferase activity, transferring glycosyl groups
G6543_RS15430	COG0463	Glycosyl transferase, family 2
G6543_RS15435	COG0726	polysaccharide deacetylase
G6543_RS15455	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G6543_RS15460	COG2205	protein histidine kinase activity
G6543_RS15505	COG1862	Preprotein translocase
G6543_RS15515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G6543_RS15520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G6543_RS15535	COG0613	PHP domain protein
G6543_RS15545	COG2350	Protein conserved in bacteria
G6543_RS15575	COG1607	acyl-coa hydrolase
G6543_RS15635	COG2199	diguanylate cyclase activity
G6543_RS15645	COG1408	metallophosphoesterase
G6543_RS15650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G6543_RS15660	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G6543_RS15680	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G6543_RS15685	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G6543_RS15700	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G6543_RS15710	COG2969	positive regulation of protein catabolic process
G6543_RS15730	COG1960	acyl-CoA dehydrogenase activity
G6543_RS15735	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G6543_RS15755	COG1309	transcriptional regulator
G6543_RS15760	COG1960	acyl-CoA dehydrogenase activity
G6543_RS15805	COG1183	phosphatidylcholine synthase activity
G6543_RS15810	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G6543_RS15840	COG1196	nuclear chromosome segregation
G6543_RS15840	COG0741	lytic transglycosylase activity
G6543_RS15840	COG0739	heme binding
G6543_RS15850	COG1702	phosphate starvation-inducible protein PhoH
G6543_RS15885	COG1295	ribonuclease BN
G6543_RS15890	COG0697	spore germination
G6543_RS15895	COG2169	Transcriptional regulator
G6543_RS15900	COG0179	Fumarylacetoacetate (FAA) hydrolase
G6543_RS15945	COG0557	exoribonuclease II activity
G6543_RS15950	COG0339	signal peptide processing
G6543_RS15955	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G6543_RS15985	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
G6543_RS15990	COG1960	acyl-CoA dehydrogenase activity
G6543_RS16145	COG0626	cystathionine gamma-synthase activity
G6543_RS16150	COG0433	COG0433 Predicted ATPase
G6543_RS16155	COG1017	nitric oxide dioxygenase activity
G6543_RS16155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G6543_RS16160	COG1959	2 iron, 2 sulfur cluster binding
G6543_RS16175	COG1301	dicarboxylic acid transport
G6543_RS16180	COG1946	Acyl-CoA thioesterase
G6543_RS16200	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G6543_RS16205	COG1040	competence protein
G6543_RS16210	COG0494	nUDIX hydrolase
G6543_RS16220	COG0598	Magnesium transport protein CorA
G6543_RS16230	COG2854	intermembrane phospholipid transfer
G6543_RS16240	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G6543_RS16245	COG1127	ABC transporter
G6543_RS16255	COG0513	Belongs to the DEAD box helicase family
G6543_RS16275	COG0408	coproporphyrinogen oxidase activity
G6543_RS16290	COG1960	acyl-CoA dehydrogenase activity
G6543_RS16300	COG1983	PspC domain protein
G6543_RS16305	COG0517	IMP dehydrogenase activity
G6543_RS16350	COG0583	DNA-binding transcription factor activity
G6543_RS16390	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS16400	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G6543_RS16405	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G6543_RS16410	COG0833	amino acid
G6543_RS16440	COG1192	Involved in chromosome partitioning
G6543_RS16445	COG0628	permease
G6543_RS16455	COG1289	transmembrane transporter activity
G6543_RS16470	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6543_RS16475	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G6543_RS16485	COG0277	FAD linked oxidase domain protein
G6543_RS16490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G6543_RS16515	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G6543_RS16520	COG5380	lipid catabolic process
G6543_RS16540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G6543_RS16590	COG0194	GDP metabolic process
G6543_RS16605	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G6543_RS16625	COG3307	-O-antigen
G6543_RS16645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G6543_RS16650	COG1704	LemA family
G6543_RS16660	COG0493	'glutamate synthase
G6543_RS16665	COG0069	glutamate synthase activity
G6543_RS16665	COG0067	glutamate synthase
G6543_RS16665	COG0070	glutamate synthase
G6543_RS16715	COG2226	methyltransferase
G6543_RS16730	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G6543_RS16735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G6543_RS16780	COG0833	amino acid
G6543_RS16865	COG0488	(ABC) transporter
G6543_RS16870	COG2873	o-acetylhomoserine
G6543_RS16875	COG4221	oxidoreductase activity
G6543_RS16880	COG0659	secondary active sulfate transmembrane transporter activity
G6543_RS16890	COG0745	RESPONSE REGULATOR receiver
G6543_RS16905	COG0427	acetyl-CoA hydrolase
G6543_RS16935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G6543_RS16965	COG2329	Antibiotic biosynthesis monooxygenase
G6543_RS16980	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G6543_RS17045	COG2249	NAD(P)H dehydrogenase (quinone) activity
G6543_RS17050	COG1733	regulation of RNA biosynthetic process
G6543_RS17080	COG0667	Aldo Keto reductase
G6543_RS17100	COG0583	DNA-binding transcription factor activity
G6543_RS17105	COG2814	Major facilitator Superfamily
G6543_RS17135	COG1335	isochorismatase
G6543_RS17145	COG1012	belongs to the aldehyde dehydrogenase family
G6543_RS17150	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
G6543_RS17160	COG1113	amino acid transport
G6543_RS17170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
G6543_RS17185	COG2814	Major facilitator Superfamily
G6543_RS17195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
G6543_RS17195	COG0352	thiamine-phosphate diphosphorylase activity
G6543_RS17195	COG0351	phosphomethylpyrimidine kinase
G6543_RS17215	COG1309	transcriptional regulator
G6543_RS17220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G6543_RS17230	COG3706	GGDEF domain
G6543_RS17240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
G6543_RS17250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G6543_RS17255	COG3162	membrane
G6543_RS17260	COG2205	protein histidine kinase activity
G6543_RS17260	COG0784	Response regulator, receiver
G6543_RS17260	COG2198	Histidine kinase
G6543_RS17285	COG3328	transposase activity
G6543_RS17290	COG1522	sequence-specific DNA binding
G6543_RS17295	COG1335	isochorismatase
G6543_RS17300	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G6543_RS17310	COG0668	transmembrane transport
G6543_RS17315	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G6543_RS17320	COG1519	Transferase
G6543_RS17325	COG1902	pentaerythritol trinitrate reductase activity
G6543_RS17345	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G6543_RS17370	COG0426	domain, Protein
G6543_RS17370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G6543_RS17390	COG2119	membrane
G6543_RS17400	COG0508	dehydrogenase complex catalyzes the overall conversion of
G6543_RS17410	COG4942	peptidase
G6543_RS17425	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G6543_RS17435	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G6543_RS17455	COG0189	ligase activity
G6543_RS17475	COG0708	Exodeoxyribonuclease III
G6543_RS17480	COG1393	Belongs to the ArsC family
G6543_RS17495	COG3706	GGDEF domain
G6543_RS17530	COG2351	hydroxyisourate hydrolase activity
G6543_RS17535	COG2233	PERMEase
G6543_RS17545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G6543_RS17555	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
G6543_RS17560	COG1028	Short-chain dehydrogenase reductase Sdr
G6543_RS17570	COG3150	esterase
G6543_RS17590	COG0791	NLP P60 protein
G6543_RS17590	COG1388	LysM domain
G6543_RS17595	COG3501	Rhs element vgr protein
G6543_RS17605	COG2918	glutathione biosynthetic process
G6543_RS17620	COG2733	membrane
G6543_RS17625	COG0436	Aminotransferase
G6543_RS17630	COG0534	Mate efflux family protein
G6543_RS17730	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G6543_RS17735	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G6543_RS17745	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G6543_RS17750	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G6543_RS17765	COG0010	Belongs to the arginase family
G6543_RS17795	COG2188	Transcriptional regulator
G6543_RS17805	COG0523	cobalamin synthesis protein
G6543_RS17815	COG1113	amino acid transport
G6543_RS17825	COG0625	glutathione transferase activity
G6543_RS17845	COG1683	Conserved Protein
G6543_RS17850	COG0534	Mate efflux family protein
G6543_RS17855	COG0385	Bile acid
G6543_RS17860	COG1335	isochorismatase
G6543_RS17865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G6543_RS17885	COG2116	formate transmembrane transporter activity
G6543_RS17890	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G6543_RS17895	COG2133	pyrroloquinoline quinone binding
G6543_RS17900	COG2983	Belongs to the UPF0260 family
G6543_RS17905	COG5487	UPF0391 membrane protein
G6543_RS17920	COG1194	a g-specific adenine glycosylase
G6543_RS17935	COG2818	Glycosylase
G6543_RS17940	COG1064	alcohol dehydrogenase
G6543_RS17945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G6543_RS17960	COG0583	DNA-binding transcription factor activity
G6543_RS17965	COG0656	L-ascorbic acid biosynthetic process
G6543_RS17970	COG2814	Major facilitator Superfamily
G6543_RS18005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G6543_RS18020	COG2233	PERMEase
G6543_RS18025	COG0583	DNA-binding transcription factor activity
G6543_RS18060	COG0733	neurotransmitter:sodium symporter activity
G6543_RS18100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G6543_RS18160	COG2951	lytic endotransglycosylase activity
G6543_RS18165	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G6543_RS18180	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G6543_RS18190	COG0671	phosphoesterase, PA-phosphatase related
G6543_RS18195	COG0861	Integral membrane protein TerC family
G6543_RS18205	COG0754	glutathionylspermidine amidase activity
G6543_RS18215	COG0402	S-adenosylhomocysteine deaminase activity
G6543_RS18230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G6543_RS18235	COG1230	cation diffusion facilitator family transporter
G6543_RS18250	COG0706	membrane insertase activity