locus-tag	class	description
HKO16_RS00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HKO16_RS00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKO16_RS00030	ENOG4105DQR	SNARE associated Golgi
HKO16_RS00035	ENOG4105C5H	ABC transporter
HKO16_RS00040	ENOG4108821	RND type efflux pump
HKO16_RS00045	ENOG4108821	RND type efflux pump
HKO16_RS00050	ENOG4108821	RND type efflux pump
HKO16_RS00060	ENOG4105D74	hydrolase
HKO16_RS00065	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HKO16_RS00070	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HKO16_RS00110	ENOG4105C8J	)-transporter
HKO16_RS00120	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HKO16_RS00150	ENOG4105C2W	permease
HKO16_RS00160	ENOG4108IG5	Transcriptional regulator
HKO16_RS00165	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HKO16_RS00200	ENOG4105F27	Major Facilitator
HKO16_RS00205	ENOG4105CV8	reductase
HKO16_RS00210	ENOG4105HEI	LysR family (Transcriptional regulator
HKO16_RS00230	ENOG4105DQ4	alcohol dehydrogenase
HKO16_RS00235	ENOG4108R3E	Dna-3-methyladenine glycosylase i
HKO16_RS00250	ENOG4105CEN	a g-specific adenine glycosylase
HKO16_RS00270	ENOG4108ZZ3	UPF0260 protein
HKO16_RS00280	ENOG4105D1H	recombination factor protein RarA
HKO16_RS00285	ENOG4105S64	Formate nitrite transporter
HKO16_RS00305	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HKO16_RS00310	ENOG4108RWI	nicotinamidase
HKO16_RS00315	ENOG4105C09	Bile acid
HKO16_RS00320	ENOG4107QI1	Mate efflux family protein
HKO16_RS00325	ENOG4105EWC	Purine nucleoside phosphorylase
HKO16_RS00345	ENOG4108RXX	maleylacetoacetate isomerase
HKO16_RS00355	ENOG4105C85	amino acid
HKO16_RS00365	ENOG4105CKI	cobalamin synthesis protein
HKO16_RS00375	ENOG4105CZE	histidine utilization repressor
HKO16_RS00380	ENOG41090B9	response to stress
HKO16_RS00395	ENOG4105C85	amino acid
HKO16_RS00405	ENOG41088SP	formiminoglutamate hydrolase
HKO16_RS00425	ENOG4108NIW	Leucine export protein LeuE
HKO16_RS00440	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HKO16_RS00450	ENOG4108ZAI	phosphatidylglycerophosphatase a
HKO16_RS00455	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HKO16_RS00470	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HKO16_RS00515	ENOG4105KHC	sulfurtransferase
HKO16_RS00530	ENOG4105BZU	Histidine kinase
HKO16_RS00535	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKO16_RS00550	ENOG4107QJQ	Mate efflux family protein
HKO16_RS00555	ENOG4105CHM	Aminotransferase
HKO16_RS00560	ENOG4106BRA	Membrane
HKO16_RS00575	ENOG4105D9M	gamma-glutamylcysteine synthetase
HKO16_RS00610	ENOG4108A65	Transcriptional regulator
HKO16_RS00615	ENOG4105CE1	Ferrous iron transport protein b
HKO16_RS00710	ENOG4105KK6	nuclease
HKO16_RS00830	ENOG4107QHF	type ii secretion system protein e
HKO16_RS00880	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HKO16_RS00885	ENOG4105FA0	parb-like partition protein
HKO16_RS00895	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HKO16_RS00900	ENOG4105KT5	UmuD protein
HKO16_RS00925	ENOG4105DR5	peptidase
HKO16_RS01095	ENOG4108K0D	peptidase, M48
HKO16_RS01160	ENOG4105CHH	sulfate transporter
HKO16_RS01170	ENOG4105C0P	Mg chelatase subunit ChlI
HKO16_RS01185	ENOG4105BZU	Histidine kinase
HKO16_RS01195	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HKO16_RS01235	ENOG4108K5H	permease YjgP YjgQ family protein
HKO16_RS01240	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HKO16_RS01245	ENOG4105CN1	protease
HKO16_RS01250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HKO16_RS01255	ENOG4107TUY	Histidine kinase
HKO16_RS01265	ENOG41061WM	D-Alanyl-D-Alanine
HKO16_RS01275	ENOG4105D6E	homoserine dehydrogenase
HKO16_RS01280	ENOG4105T95	Thiol disulfide interChange protein
HKO16_RS01285	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKO16_RS01295	ENOG4105CE1	Ferrous iron transport protein b
HKO16_RS01310	ENOG4105CNI	cell division protein FtsW
HKO16_RS01315	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HKO16_RS01325	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HKO16_RS01350	ENOG4108RNG	Permease of the drug metabolite transporter
HKO16_RS01355	ENOG4105DFG	type I secretion outer membrane protein
HKO16_RS01360	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HKO16_RS01375	ENOG4108HRK	Histidine kinase
HKO16_RS01380	ENOG4108NEV	two component transcriptional regulator, LytTR family
HKO16_RS01385	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HKO16_RS01415	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
HKO16_RS01430	ENOG4105GVR	general secretion pathway protein D
HKO16_RS01435	ENOG4105TV9	FHA Domain-Containing protein
HKO16_RS01440	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HKO16_RS01480	ENOG4105PM1	preprotein translocase subunit SecE
HKO16_RS01485	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HKO16_RS01535	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HKO16_RS01540	ENOG4105D3Y	Na H antiporter
HKO16_RS01555	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HKO16_RS01570	ENOG4107ZXU	DSBA oxidoreductase
HKO16_RS01635	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HKO16_RS01640	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HKO16_RS01670	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HKO16_RS01680	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HKO16_RS01695	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HKO16_RS01705	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
HKO16_RS01720	ENOG4107QHF	type ii secretion system protein e
HKO16_RS01730	ENOG4107EJC	Preprotein translocase subunit SecG
HKO16_RS01750	ENOG4105CHV	Transcription elongation factor NusA
HKO16_RS01765	ENOG4105KJM	monovalent cation h antiporter subunit g
HKO16_RS01770	ENOG4105W4C	monovalent cation H antiporter subunit F
HKO16_RS01775	ENOG4105SC1	monovalent cation H antiporter subunit E
HKO16_RS01780	ENOG4107R4Z	monovalent cation h antiporter subunit d
HKO16_RS01785	ENOG4108ZE9	Monovalent cation H antiporter subunit C
HKO16_RS01790	ENOG4105D65	subunit l
HKO16_RS01805	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HKO16_RS01825	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HKO16_RS01835	ENOG4105CSR	polyphosphate kinase 2
HKO16_RS01845	ENOG4105DSY	exodeoxyribonuclease V, gamma
HKO16_RS01850	ENOG4107QKA	exodeoxyribonuclease V beta
HKO16_RS01855	ENOG4107QYX	exodeoxyribonuclease v alpha
HKO16_RS01875	ENOG4107QUT	magnesium and cobalt transport protein CorA
HKO16_RS01880	ENOG4108ZKH	Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity)
HKO16_RS01885	ENOG4105DVC	DnaJ domain protein
HKO16_RS01900	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HKO16_RS01905	ENOG4105C25	Primosomal protein n'
HKO16_RS01910	ENOG4105D7Q	type ii secretion system
HKO16_RS01915	ENOG4108VAU	general secretion pathway protein G
HKO16_RS01925	ENOG4108Z7R	Chaperone CsaA
HKO16_RS01930	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HKO16_RS01935	ENOG4108JU5	Magnesium and cobalt efflux protein
HKO16_RS01940	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HKO16_RS01950	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HKO16_RS01960	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HKO16_RS01975	ENOG4105C5X	domain protein
HKO16_RS01980	ENOG4108BEW	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HKO16_RS01990	ENOG4105BZ8	glutamate synthase
HKO16_RS02020	ENOG4107T8P	acyl-Coa dehydrogenase
HKO16_RS02030	ENOG4107QI1	Mate efflux family protein
HKO16_RS02040	ENOG4105CSA	Coproporphyrinogen iii oxidase
HKO16_RS02050	ENOG4105CBN	LysR family transcriptional regulator
HKO16_RS02065	ENOG4105J5T	Amp-dependent synthetase and ligase
HKO16_RS02070	ENOG4105C03	ribonuclease
HKO16_RS02075	ENOG4105EI2	Pseudouridine synthase
HKO16_RS02080	ENOG4107XGZ	Hydrolase
HKO16_RS02085	ENOG4105D29	Helix-turn-helix type 11 domain protein
HKO16_RS02100	ENOG4108W5M	transcriptional regulator
HKO16_RS02115	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HKO16_RS02130	ENOG4105DUM	transcriptional regulator, lysR family
HKO16_RS02155	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HKO16_RS02210	ENOG4105CK2	sodium dicarboxylate symporter
HKO16_RS02220	ENOG4105D1S	lipid A biosynthesis
HKO16_RS02225	ENOG4105N14	lysine exporter protein LysE YggA
HKO16_RS02230	ENOG4105C5H	ABC transporter
HKO16_RS02245	ENOG4105KVH	Transcriptional regulator
HKO16_RS02255	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HKO16_RS02270	ENOG4105C4R	Atp-dependent dna helicase
HKO16_RS02275	ENOG4105VFU	Rna-binding protein
HKO16_RS02295	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
HKO16_RS02310	ENOG4107RGH	Aldehyde dehydrogenase
HKO16_RS02320	ENOG4105CIY	formyltetrahydrofolate deformylase
HKO16_RS02420	ENOG4105DWV	Homoserine O-trans-acetylase
HKO16_RS02440	ENOG4108ESX	Receptor
HKO16_RS02450	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HKO16_RS02470	ENOG4107GFK	fumarate
HKO16_RS02475	ENOG4108DNC	Involved in acetate metabolism (By similarity)
HKO16_RS02480	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HKO16_RS02485	ENOG4105C01	Dihydroxy-acid dehydratase
HKO16_RS02490	ENOG4108UHU	Aldolase
HKO16_RS02495	ENOG4105C6Z	Gluconate
HKO16_RS02500	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
HKO16_RS02505	ENOG4105C26	Dehydrogenase
HKO16_RS02515	ENOG4106HB6	Alpha beta hydrolase
HKO16_RS02530	ENOG4105CN1	protease
HKO16_RS02545	ENOG4105WVQ	Fe-S assembly protein IscX
HKO16_RS02565	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
HKO16_RS02585	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HKO16_RS02605	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HKO16_RS02620	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS02625	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HKO16_RS02635	ENOG4105C84	Histidine ammonia-lyase
HKO16_RS02665	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HKO16_RS02675	ENOG4105C2D	reductase
HKO16_RS02680	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HKO16_RS02700	ENOG4105VW4	glutaredoxin 3
HKO16_RS02710	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HKO16_RS02715	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
HKO16_RS02725	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HKO16_RS02730	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HKO16_RS02735	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HKO16_RS02740	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HKO16_RS02765	ENOG4105C7K	acetolactate synthase
HKO16_RS02770	ENOG4108ZP8	Acetolactate synthase small subunit
HKO16_RS02780	ENOG4105BZU	Histidine kinase
HKO16_RS02820	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HKO16_RS02835	ENOG4105F8V	Hydrolase, tatD family
HKO16_RS02840	ENOG4107QM5	aconitate hydratase
HKO16_RS02845	ENOG4105CUZ	uba thif-type nad fad binding protein
HKO16_RS02855	ENOG4107RSM	transcriptional regulator
HKO16_RS02865	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HKO16_RS02880	ENOG4106UX7	integral membrane protein
HKO16_RS02885	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HKO16_RS02890	ENOG4105W8H	transhydrogenase (subunit alpha
HKO16_RS02895	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HKO16_RS02910	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
HKO16_RS02915	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HKO16_RS02920	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HKO16_RS02925	ENOG4105BZU	Histidine kinase
HKO16_RS02930	ENOG4105C6T	cysteine synthase
HKO16_RS02945	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKO16_RS02955	ENOG4105DXN	mazG family
HKO16_RS02960	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
HKO16_RS02965	ENOG4105DJ0	Poly(A) Polymerase
HKO16_RS02970	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKO16_RS02990	ENOG41080Z8	PHOSPHOCARRIER protein
HKO16_RS02995	ENOG4105N42	UPF0307 protein
HKO16_RS03000	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS03015	ENOG4105CYM	Glutathione S-transferase
HKO16_RS03020	ENOG4105W39	Membrane
HKO16_RS03060	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HKO16_RS03080	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HKO16_RS03090	ENOG4105C9X	ppx gppa phosphatase
HKO16_RS03100	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HKO16_RS03105	ENOG4105II7	pyrroline-5-carboxylate reductase
HKO16_RS03110	ENOG4108VIA	integral membrane protein
HKO16_RS03115	ENOG4105C2M	dna polymerase I
HKO16_RS03135	ENOG4107QHF	type ii secretion system protein e
HKO16_RS03140	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HKO16_RS03145	ENOG4105K56	Transcriptional regulator
HKO16_RS03215	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HKO16_RS03220	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HKO16_RS03225	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HKO16_RS03235	ENOG4105CRQ	synthase (Component I)
HKO16_RS03280	ENOG4108Z0R	Transferase
HKO16_RS03285	ENOG41072GX	Peptidase M22 Glycoprotease
HKO16_RS03310	ENOG4105DJV	ribulose-phosphate 3-epimerase
HKO16_RS03315	ENOG4108HCJ	Hydrolase
HKO16_RS03325	ENOG4105E3B	Multicopper oxidase
HKO16_RS03345	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HKO16_RS03350	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HKO16_RS03355	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HKO16_RS03390	ENOG4105ETT	transcriptional Regulator, LysR family
HKO16_RS03395	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS03400	ENOG4107RGD	Major Facilitator superfamily
HKO16_RS03405	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HKO16_RS03415	ENOG4107EFR	Flavocytochrome c
HKO16_RS03420	ENOG4106P55	Transcriptional regulator
HKO16_RS03435	ENOG4106P55	Transcriptional regulator
HKO16_RS03445	ENOG4105CH2	amidohydrolase
HKO16_RS03465	ENOG4105ETT	transcriptional Regulator, LysR family
HKO16_RS03480	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
HKO16_RS03525	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKO16_RS03535	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HKO16_RS03540	ENOG4107EXC	regulatoR
HKO16_RS03545	ENOG4105E0F	Histidine kinase
HKO16_RS03555	ENOG4105BZU	Histidine kinase
HKO16_RS03575	ENOG4105GKE	subunit e
HKO16_RS03580	ENOG4107QIZ	NADH dehydrogenase
HKO16_RS03585	ENOG4108IEH	NADH dehydrogenase subunit g
HKO16_RS03600	ENOG4107UFS	subunit j
HKO16_RS03610	ENOG4105D65	subunit l
HKO16_RS03615	ENOG4105C8S	subunit m
HKO16_RS03640	ENOG4105DUM	transcriptional regulator, lysR family
HKO16_RS03645	ENOG4105DP0	ferredoxin-NADP reductase
HKO16_RS03670	ENOG4105CBX	hi0933 family
HKO16_RS03675	ENOG4105K6H	D-cysteine desulfhydrase
HKO16_RS03705	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HKO16_RS03715	ENOG4105D1F	ATP-binding protein
HKO16_RS03765	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
HKO16_RS03775	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKO16_RS03790	ENOG4105HF0	Membrane
HKO16_RS03800	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HKO16_RS03820	ENOG4106UW1	Major Facilitator superfamily
HKO16_RS03825	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
HKO16_RS03830	ENOG4108K4C	ec 3.1.3.12
HKO16_RS03835	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HKO16_RS03845	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HKO16_RS03850	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HKO16_RS03860	ENOG4105FE9	pseudouridine synthase
HKO16_RS03865	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HKO16_RS03870	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
HKO16_RS03875	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HKO16_RS03880	ENOG4108BPE	-transporting atpase
HKO16_RS03885	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HKO16_RS03895	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HKO16_RS03900	ENOG4105CHR	reductase
HKO16_RS03910	ENOG4109066	lysm domain bon superfamily protein
HKO16_RS03915	ENOG4105DWF	phosphomethylpyrimidine kinase
HKO16_RS03925	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HKO16_RS03955	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HKO16_RS03985	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HKO16_RS04000	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HKO16_RS04005	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKO16_RS04010	ENOG4105C34	Pseudouridine synthase
HKO16_RS04015	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HKO16_RS04035	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HKO16_RS04055	ENOG4105EJC	lysr family transcriptional regulator
HKO16_RS04060	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HKO16_RS04065	ENOG4105C94	Transporter
HKO16_RS04075	ENOG4105DVW	rieske (2Fe-2S)
HKO16_RS04080	ENOG4105C26	Dehydrogenase
HKO16_RS04085	ENOG4105E3J	oxidoreductase
HKO16_RS04100	ENOG4105C4K	Nad synthetase
HKO16_RS04110	ENOG4105EUB	pirin domain protein
HKO16_RS04115	ENOG4108YXA	Membrane
HKO16_RS04160	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HKO16_RS04170	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HKO16_RS04175	ENOG4105C3M	thioredoxin reductase
HKO16_RS04180	ENOG4105CNU	cell division protein FtsK
HKO16_RS04185	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
HKO16_RS04200	ENOG4107QMS	site-determining protein
HKO16_RS04215	ENOG4106HNH	Acyl-transferase
HKO16_RS04220	ENOG4108ZG0	Ompa motb domain protein
HKO16_RS04225	ENOG4105C4R	Atp-dependent dna helicase
HKO16_RS04235	ENOG4107QKV	phosphomannomutase
HKO16_RS04250	ENOG4105E7A	Glutamine amidotransferase
HKO16_RS04265	ENOG4105VDB	UPF0125 protein
HKO16_RS04275	ENOG41090R7	Ferric uptake
HKO16_RS04280	ENOG4105CZX	twitching motility protein
HKO16_RS04285	ENOG4105CZX	twitching motility protein
HKO16_RS04290	ENOG4105DFA	alanine racemase domain protein
HKO16_RS04295	ENOG4105EYH	Exonuclease
HKO16_RS04300	ENOG4107RH8	nuclease SbcCD subunit D
HKO16_RS04320	ENOG4105ECP	epimerase
HKO16_RS04325	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HKO16_RS04330	ENOG4105D52	delta-aminolevulinic acid dehydratase
HKO16_RS04335	ENOG4108VUY	thioesterase Superfamily protein
HKO16_RS04340	ENOG4105CW7	secretion protein, HlyD family
HKO16_RS04345	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HKO16_RS04350	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HKO16_RS04390	ENOG4105C54	Major Facilitator superfamily
HKO16_RS04395	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HKO16_RS04420	ENOG4105D5Q	Arginine ornithine antiporter
HKO16_RS04425	ENOG4107QK5	Homocysteine s-methyltransferase
HKO16_RS04450	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HKO16_RS04455	ENOG4105C94	Transporter
HKO16_RS04460	ENOG4105C94	Transporter
HKO16_RS04470	ENOG4108S4H	thioesterase Superfamily protein
HKO16_RS04480	ENOG4105CKI	cobalamin synthesis protein
HKO16_RS04490	ENOG4108VWS	Yaeq family
HKO16_RS04500	ENOG4107BJW	polysaccharide deacetylase
HKO16_RS04505	ENOG4105CND	Glycosyl transferase, family 2
HKO16_RS04515	ENOG4106YT9	Enoyl-CoA hydratase
HKO16_RS04530	ENOG41069M3	Transcriptional regulator
HKO16_RS04550	ENOG4105CHR	reductase
HKO16_RS04560	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
HKO16_RS04565	ENOG4105DJB	Major Facilitator Superfamily
HKO16_RS04575	ENOG4108MXF	Alpha Beta Hydrolase
HKO16_RS04580	ENOG4105CHR	reductase
HKO16_RS04595	ENOG4105C7K	acetolactate synthase
HKO16_RS04605	ENOG4105CSH	Transporter
HKO16_RS04610	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HKO16_RS04615	ENOG4105CSV	Glutaminase
HKO16_RS04620	ENOG4108R6W	Transcriptional regulator, ARAC family
HKO16_RS04625	ENOG4105EU0	Major facilitator Superfamily
HKO16_RS04635	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
HKO16_RS04645	ENOG4108PZW	LysR family Transcriptional regulator
HKO16_RS04655	ENOG4105CSP	Major Facilitator Superfamily
HKO16_RS04670	ENOG4105C3R	Methionine synthase
HKO16_RS04675	ENOG4105CJ3	phosphate transporter
HKO16_RS04695	ENOG4105E6M	Sulphatase-modifying factor protein
HKO16_RS04700	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
HKO16_RS04715	ENOG4107RNH	Outer membrane receptor FepA
HKO16_RS04735	ENOG4108UJV	acyl-CoA thioesterase i
HKO16_RS04740	ENOG4108I0Y	(ABC) transporter
HKO16_RS04745	ENOG4105CV6	ABC transporter, permease
HKO16_RS04750	ENOG4107U91	Rhomboid family
HKO16_RS04775	ENOG4105C5Q	Transcriptional regulator
HKO16_RS04785	ENOG4107QZF	nitrite reductase NADPH large subunit
HKO16_RS04790	ENOG4105VCQ	rubredoxin
HKO16_RS04810	ENOG4108MRJ	
HKO16_RS04825	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
HKO16_RS04840	ENOG4105D4T	Citrate transporter
HKO16_RS04845	ENOG4105C37	(CBS) domain
HKO16_RS04855	ENOG4107RET	Isocitrate lyase
HKO16_RS04890	ENOG4105CQM	Urea amidohydrolase subunit alpha
HKO16_RS04900	ENOG4108WKG	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HKO16_RS04915	ENOG4106H78	methyltransferase
HKO16_RS04920	ENOG4105CJN	penicillin-binding protein
HKO16_RS04945	ENOG4105CSM	endonuclease III
HKO16_RS04950	ENOG4108R3D	Electron transport complex
HKO16_RS04955	ENOG4105D82	Glutamate dehydrogenase
HKO16_RS04965	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
HKO16_RS04990	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HKO16_RS05030	ENOG4107RAQ	aminopeptidase
HKO16_RS05035	ENOG4105D0A	hydroxylase
HKO16_RS05040	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HKO16_RS05060	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
HKO16_RS05065	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
HKO16_RS05075	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HKO16_RS05085	ENOG4105W4M	Transport-associated protein
HKO16_RS05095	ENOG4105E09	nadh pyrophosphatase
HKO16_RS05105	ENOG4107RZZ	dna polymerase iii epsilon subunit
HKO16_RS05110	ENOG4105E9H	Lytic Murein transglycosylase
HKO16_RS05110	ENOG4105E9H	Lytic Murein transglycosylase
HKO16_RS05120	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
HKO16_RS05125	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
HKO16_RS05130	ENOG4108JQ5	ABC transporter
HKO16_RS05150	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
HKO16_RS05175	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HKO16_RS05210	ENOG4105M4H	endoribonuclease L-psp
HKO16_RS05215	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HKO16_RS05220	ENOG4105CR8	Transcriptional regulator
HKO16_RS05240	ENOG4105D01	(LipO)protein
HKO16_RS05265	ENOG4105C85	amino acid
HKO16_RS05275	ENOG4105CUB	amino acid
HKO16_RS05295	ENOG4105C26	Dehydrogenase
HKO16_RS05315	ENOG4105C85	amino acid
HKO16_RS05335	ENOG4107RGH	Aldehyde dehydrogenase
HKO16_RS05340	ENOG4108ZX5	transcriptional regulator
HKO16_RS05345	ENOG4105DJP	Membrane
HKO16_RS05350	ENOG4105CTX	dehydratase
HKO16_RS05355	ENOG4105DJB	Major Facilitator Superfamily
HKO16_RS05360	ENOG4105EQX	glucarate dehydratase
HKO16_RS05370	ENOG4105CZJ	Aldehyde dehydrogenase
HKO16_RS05375	ENOG4105JXH	GntR family transcriptional regulator
HKO16_RS05390	ENOG4105NI3	Protein of unknown function (DUF3237)
HKO16_RS05395	ENOG4105EPF	Outer membrane porin
HKO16_RS05400	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS05415	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
HKO16_RS05420	ENOG4108SC4	)-transporter
HKO16_RS05435	ENOG4105E3J	oxidoreductase
HKO16_RS05445	ENOG4105D2S	major facilitator superfamily
HKO16_RS05450	ENOG4105EPF	Outer membrane porin
HKO16_RS05470	ENOG4107RN6	Monooxygenase
HKO16_RS05480	ENOG4105JQZ	Methyltransferase
HKO16_RS05485	ENOG4105F95	Monooxygenase
HKO16_RS05520	ENOG4105F95	Monooxygenase
HKO16_RS05530	ENOG4105C7N	Xanthine uracil vitamin C permease
HKO16_RS05535	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
HKO16_RS05540	ENOG4105CPW	cytochrome b561
HKO16_RS05550	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HKO16_RS05560	ENOG4105CFH	Aspartokinase
HKO16_RS05610	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HKO16_RS05615	ENOG4105W7J	DNA binding
HKO16_RS05700	ENOG4107ZQ5	Phage-associated protein, HI1409 family
HKO16_RS05720	ENOG41090AG	Bacteriophage protein
HKO16_RS05855	ENOG4105DFP	Integrase
HKO16_RS05865	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HKO16_RS05875	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HKO16_RS05890	ENOG4105CPC	Aldo Keto reductase
HKO16_RS05895	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HKO16_RS05900	ENOG4108UKZ	OsmC family
HKO16_RS05915	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKO16_RS05945	ENOG4105CD3	dihydroorotase
HKO16_RS05950	ENOG4108ZG0	Ompa motb domain protein
HKO16_RS05960	ENOG4108TGY	Glutathione S-transferase
HKO16_RS05965	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HKO16_RS05975	ENOG4108K3A	Glutathione S-transferase
HKO16_RS05985	ENOG4108JU3	Alkyl hydroperoxide reductase
HKO16_RS05995	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HKO16_RS06005	ENOG4105D3R	alkyl hydroperoxide reductase
HKO16_RS06010	ENOG4105CQ7	ATP-dependent helicase
HKO16_RS06025	ENOG4105D2S	major facilitator superfamily
HKO16_RS06030	ENOG4105DKK	Benzoate
HKO16_RS06035	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
HKO16_RS06040	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
HKO16_RS06045	ENOG4108UKV	benzoate 1,2-dioxygenase
HKO16_RS06050	ENOG4105FUY	alpha subunit
HKO16_RS06055	ENOG4108KB2	LysR family Transcriptional regulator
HKO16_RS06105	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HKO16_RS06135	ENOG410829K	Lysine exporter protein (Lyse ygga)
HKO16_RS06140	ENOG4105VEQ	Cold shock protein
HKO16_RS06150	ENOG4105II7	pyrroline-5-carboxylate reductase
HKO16_RS06210	ENOG4105C2X	Arabinose 5-phosphate isomerase
HKO16_RS06225	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
HKO16_RS06230	ENOG4108IUZ	ABC transporter
HKO16_RS06235	ENOG4105DFG	type I secretion outer membrane protein
HKO16_RS06275	ENOG4108Z4U	Ferredoxin
HKO16_RS06300	ENOG4105BZU	Histidine kinase
HKO16_RS06305	ENOG4105D1S	lipid A biosynthesis
HKO16_RS06310	ENOG4105D7N	magnesium and cobalt transport protein CorA
HKO16_RS06325	ENOG4105D2S	major facilitator superfamily
HKO16_RS06345	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
HKO16_RS06380	ENOG4108WAV	Transcriptional regulator
HKO16_RS06385	ENOG4105C5A	transporter
HKO16_RS06405	ENOG4108JIK	carboxylase
HKO16_RS06410	ENOG4107R4J	Chloride channel
HKO16_RS06420	ENOG4105R8C	Transcriptional regulator
HKO16_RS06430	ENOG4105E2A	Dehydrogenase
HKO16_RS06445	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HKO16_RS06450	ENOG4108MXQ	glutathione-regulated potassium-efflux system ancillary protein KefF
HKO16_RS06470	ENOG4105MRR	Transcriptional regulator (By similarity)
HKO16_RS06480	ENOG4108HW3	(ABC) transporter
HKO16_RS06510	ENOG4105E6M	Sulphatase-modifying factor protein
HKO16_RS06575	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKO16_RS06605	ENOG4105EMY	transcriptional regulator
HKO16_RS06615	ENOG4107Y2X	deaminase
HKO16_RS06620	ENOG4105DJ2	Major Facilitator Superfamily
HKO16_RS06635	ENOG4105WPN	DNA integration recombination invertion protein
HKO16_RS06645	ENOG4108Z4X	TRANSCRIPTIONal
HKO16_RS06655	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HKO16_RS06675	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HKO16_RS06700	ENOG4105CZJ	Aldehyde dehydrogenase
HKO16_RS06705	ENOG4107QTZ	amino acid
HKO16_RS06710	ENOG4105EJQ	L-serine dehydratase
HKO16_RS06715	ENOG4105DXM	phenylacetic acid degradation protein
HKO16_RS06720	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HKO16_RS06725	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HKO16_RS06730	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HKO16_RS06735	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HKO16_RS06740	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HKO16_RS06745	ENOG4105E39	Enoyl-CoA hydratase
HKO16_RS06750	ENOG4108UKI	Enoyl-CoA hydratase
HKO16_RS06755	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HKO16_RS06760	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS06765	ENOG4105DZS	Phenylacetate-CoA ligase
HKO16_RS06770	ENOG4105V9J	phenylacetic acid degradation operon negative regulatory protein
HKO16_RS06775	ENOG4108Z0R	Transferase
HKO16_RS06780	ENOG4107YAU	phenylacetic acid degradation protein
HKO16_RS06810	ENOG4107VGR	Catalase
HKO16_RS06815	ENOG4105CPW	cytochrome b561
HKO16_RS06820	ENOG4105HEI	LysR family (Transcriptional regulator
HKO16_RS06830	ENOG4107HP6	Transcriptional regulator
HKO16_RS06835	ENOG41072AC	4-hydroxybenzoate 3-monooxygenase
HKO16_RS06850	ENOG4105C4Y	ABC transporter
HKO16_RS06855	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HKO16_RS06860	ENOG4107RCV	ABC transporter, permease
HKO16_RS06870	ENOG4107STF	Involved in phosphonate degradation (By similarity)
HKO16_RS06875	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
HKO16_RS06895	ENOG4105CC0	LysR family Transcriptional regulator
HKO16_RS06910	ENOG4105E39	Enoyl-CoA hydratase
HKO16_RS06915	ENOG4107QX3	carboxylase
HKO16_RS06920	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS06925	ENOG4105R8C	Transcriptional regulator
HKO16_RS06930	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS06950	ENOG4105HEI	LysR family (Transcriptional regulator
HKO16_RS07000	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
HKO16_RS07030	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS07040	ENOG4105BZU	Histidine kinase
HKO16_RS07045	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
HKO16_RS07060	ENOG4105EAD	ABC transporter
HKO16_RS07065	ENOG4108HW4	amino acid AbC transporter
HKO16_RS07075	ENOG4107RP9	extracellular solute-binding protein, family 3
HKO16_RS07080	ENOG4105CT1	(ABC) transporter
HKO16_RS07090	ENOG4105EXG	Transcriptional regulator
HKO16_RS07105	ENOG4105C9B	Cysteine desulfurase
HKO16_RS07110	ENOG4105ESN	nucleotide-binding protein
HKO16_RS07115	ENOG4105D7W	serine acetyltransferase
HKO16_RS07125	ENOG4105CHR	reductase
HKO16_RS07130	ENOG4105CBN	LysR family transcriptional regulator
HKO16_RS07135	ENOG4105CYM	Glutathione S-transferase
HKO16_RS07140	ENOG4108SHQ	Glutathione S-transferase
HKO16_RS07145	ENOG4105CMU	LysR family (Transcriptional regulator
HKO16_RS07150	ENOG4105VAW	lrga family
HKO16_RS07155	ENOG41067MG	lrgb family
HKO16_RS07160	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKO16_RS07175	ENOG4105DXI	Major Facilitator superfamily
HKO16_RS07185	ENOG4105ETT	transcriptional Regulator, LysR family
HKO16_RS07195	ENOG4108K6F	triphosphoribosyl-dephospho-CoA synthase
HKO16_RS07200	ENOG4105WSE	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
HKO16_RS07215	ENOG4105PSI	phosphoribosyl-dephospho-CoA transferase
HKO16_RS07220	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HKO16_RS07235	ENOG4108K70	Transcriptional regulator
HKO16_RS07240	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKO16_RS07250	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HKO16_RS07255	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HKO16_RS07275	ENOG4105C54	Major Facilitator superfamily
HKO16_RS07285	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HKO16_RS07290	ENOG4108IY8	ABC, transporter
HKO16_RS07295	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
HKO16_RS07310	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
HKO16_RS07320	ENOG4105CBN	LysR family transcriptional regulator
HKO16_RS07330	ENOG4105CPN	adenine deaminase
HKO16_RS07345	ENOG41082YX	Transcriptional regulator, arsr family
HKO16_RS07350	ENOG4105D6J	arsenicaL-resistance protein
HKO16_RS07355	ENOG4108KB2	LysR family Transcriptional regulator
HKO16_RS07370	ENOG4108JU3	Alkyl hydroperoxide reductase
HKO16_RS07395	ENOG4105C0B	DNA polymerase III (alpha subunit)
HKO16_RS07405	ENOG4105CK2	sodium dicarboxylate symporter
HKO16_RS07410	ENOG4105CHM	Aminotransferase
HKO16_RS07420	ENOG4108V06	Glutathione peroxidase
HKO16_RS07425	ENOG4105E7U	AraC family transcriptional regulator
HKO16_RS07455	ENOG4105ZED	uncharacterized protein ygaH
HKO16_RS07460	ENOG4108UMN	azlc family
HKO16_RS07485	ENOG4105C3G	gtp-binding protein
HKO16_RS07490	ENOG4108UMI	ABC transporter, permease
HKO16_RS07495	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKO16_RS07500	ENOG4105D01	(LipO)protein
HKO16_RS07505	ENOG4105D01	(LipO)protein
HKO16_RS07520	ENOG4107T8P	acyl-Coa dehydrogenase
HKO16_RS07535	ENOG4105EAD	ABC transporter
HKO16_RS07540	ENOG4105DRP	amino acid AbC transporter
HKO16_RS07545	ENOG4105CDA	abc transporter atp-binding protein
HKO16_RS07555	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS07570	ENOG41067SE	Tetr family transcriptional regulator
HKO16_RS07590	ENOG4105CC0	LysR family Transcriptional regulator
HKO16_RS07600	ENOG4105ETS	cytosine purines uracil thiamine allantoin
HKO16_RS07610	ENOG4108IPJ	Membrane
HKO16_RS07635	ENOG4105GQR	Chaperone
HKO16_RS07640	ENOG4105X0I	Fimbrial
HKO16_RS07660	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HKO16_RS07665	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HKO16_RS07685	ENOG4108HWY	Beta-lactamase
HKO16_RS07710	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HKO16_RS07720	ENOG4108YYC	ycei family
HKO16_RS07730	ENOG4108T58	Mg2 transport protein CorA
HKO16_RS07745	ENOG4105YGK	Pfam:UPF0157
HKO16_RS07750	ENOG4105C26	Dehydrogenase
HKO16_RS07755	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS07760	ENOG4105CK7	Sodium proline symporter
HKO16_RS07765	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HKO16_RS07775	ENOG4108ZX5	transcriptional regulator
HKO16_RS07785	ENOG4105BZ1	(ABC) transporter
HKO16_RS07790	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
HKO16_RS07795	ENOG4105XPP	Protein of unknown function (DUF1275)
HKO16_RS07805	ENOG41080HT	Transcriptional regulator, arsr family
HKO16_RS07815	ENOG4105EZE	Cupin 4 family protein
HKO16_RS07820	ENOG4108UHJ	MAF-like protein
HKO16_RS07840	ENOG4105D2N	Aldolase
HKO16_RS07845	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HKO16_RS07850	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HKO16_RS07855	ENOG4105EHM	Aminoglycoside phosphotransferase
HKO16_RS07860	ENOG4108S0S	Nucleotidyl transferase
HKO16_RS07870	ENOG4107QJE	Chromosome Partitioning Protein
HKO16_RS07875	ENOG4105FA0	parb-like partition protein
HKO16_RS07890	ENOG4105BZ1	(ABC) transporter
HKO16_RS07895	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HKO16_RS07905	ENOG4107QRG	dna polymerase iii
HKO16_RS07915	ENOG4105F8V	Hydrolase, tatD family
HKO16_RS07940	ENOG4108RTD	type II secretion system protein K
HKO16_RS07960	ENOG4108Z6B	deaminase
HKO16_RS07975	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HKO16_RS07980	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HKO16_RS08000	ENOG4107RN6	Monooxygenase
HKO16_RS08010	ENOG4105D6Z	AFG1 family ATPase
HKO16_RS08085	ENOG4105CDU	Replicative dna helicase
HKO16_RS08175	ENOG4105EFC	phage portal protein HK97 family
HKO16_RS08280	ENOG4107QP3	malate synthase g
HKO16_RS08290	ENOG4105SG9	biopolymer transport protein, ExbD
HKO16_RS08330	ENOG4105DGW	oligopeptidase A
HKO16_RS08340	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HKO16_RS08360	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HKO16_RS08375	ENOG4105K4T	epimerase
HKO16_RS08380	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HKO16_RS08400	ENOG4108JA2	transcriptioN-repair coupling factor
HKO16_RS08410	ENOG4105F8J	Adenylate Guanylate cyclase
HKO16_RS08415	ENOG4108ZIT	Ferredoxin, 2FE-2S
HKO16_RS08430	ENOG4108Z4V	iron-sulfur cluster assembly
HKO16_RS08435	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
HKO16_RS08445	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
HKO16_RS08460	ENOG4105K70	DNA-binding protein
HKO16_RS08470	ENOG4105E7U	AraC family transcriptional regulator
HKO16_RS08475	ENOG4105EEF	Alkane 1-monooxygenase
HKO16_RS08480	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS08485	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS08500	ENOG4108Z66	YbaK ebsC protein
HKO16_RS08515	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HKO16_RS08520	ENOG4105DUU	IucA IucC family protein
HKO16_RS08525	ENOG4105DJU	Siderophore biosynthesis protein
HKO16_RS08535	ENOG4105JSC	dimethylmenaquinone methyltransferase
HKO16_RS08565	ENOG4107VXZ	Hydrolase
HKO16_RS08575	ENOG4108YZT	Adenosylcobinamide kinase
HKO16_RS08580	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HKO16_RS08585	ENOG4107TB6	phosphoglycerate mutase
HKO16_RS08600	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HKO16_RS08605	ENOG4107TSN	permease
HKO16_RS08625	ENOG4105CNM	Receptor
HKO16_RS08630	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HKO16_RS08645	ENOG4105CJ1	ABC, transporter
HKO16_RS08650	ENOG4107QWP	ABC-2 type transporter
HKO16_RS08655	ENOG4107QWP	ABC-2 type transporter
HKO16_RS08680	ENOG4105K59	histidine triad (HIT) protein
HKO16_RS08710	ENOG4105F2W	methyltransferase
HKO16_RS08720	ENOG4105C28	cystathionine
HKO16_RS08735	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HKO16_RS08740	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
HKO16_RS08770	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HKO16_RS08780	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HKO16_RS08785	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HKO16_RS08795	ENOG4105BZU	Histidine kinase
HKO16_RS08810	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HKO16_RS08815	ENOG4107R0V	Pyruvate dehydrogenase
HKO16_RS08820	ENOG4105CPP	Dehydrogenase, E1 component
HKO16_RS08835	ENOG4105CHR	reductase
HKO16_RS08845	ENOG4105FFC	UPF0187 protein
HKO16_RS08855	ENOG4107S76	domain protein
HKO16_RS08865	ENOG4108VCT	Sulfite exporter TauE/SafE
HKO16_RS08880	ENOG4105UEI	Transcriptional Regulator AraC Family
HKO16_RS08885	ENOG4105KVH	Transcriptional regulator
HKO16_RS08890	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HKO16_RS08915	ENOG4106FTQ	Taurine ABC transporter, periplasmic
HKO16_RS08920	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HKO16_RS08940	ENOG4105CSH	Transporter
HKO16_RS08950	ENOG4108IJ0	Aspartate ammonia-lyase
HKO16_RS08965	ENOG4107YNJ	LysR family Transcriptional regulator
HKO16_RS08975	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS08980	ENOG4105CRW	Short chain fatty acid transporter
HKO16_RS08995	ENOG4108M0I	Transcriptional regulator
HKO16_RS09015	ENOG4108IND	Tetr family transcriptional regulator
HKO16_RS09025	ENOG4105CY2	Citrate transporter
HKO16_RS09030	ENOG4105DTD	Dehydrogenase
HKO16_RS09035	ENOG4105CF7	AraC family transcriptional regulator
HKO16_RS09040	ENOG4105D2S	major facilitator superfamily
HKO16_RS09050	ENOG4105CHR	reductase
HKO16_RS09095	ENOG4105BZS	acriflavin resistance protein
HKO16_RS09100	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HKO16_RS09105	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKO16_RS09110	ENOG4105E0F	Histidine kinase
HKO16_RS09120	ENOG4108821	RND type efflux pump
HKO16_RS09125	ENOG4108R6W	Transcriptional regulator, ARAC family
HKO16_RS09175	ENOG4105M03	Domain of unknown function (DUF955)
HKO16_RS09210	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HKO16_RS09285	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HKO16_RS09305	ENOG4105E0A	ABC, transporter
HKO16_RS09310	ENOG4105EHG	Permease protein
HKO16_RS09320	ENOG4105DQ4	alcohol dehydrogenase
HKO16_RS09325	ENOG4105CF7	AraC family transcriptional regulator
HKO16_RS09330	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HKO16_RS09340	ENOG4105EXW	epimerase dehydratase
HKO16_RS09345	ENOG4105DDW	LysR family Transcriptional regulator
HKO16_RS09360	ENOG4105CZJ	Aldehyde dehydrogenase
HKO16_RS09375	ENOG4105CW7	secretion protein, HlyD family
HKO16_RS09390	ENOG4106P55	Transcriptional regulator
HKO16_RS09485	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS09495	ENOG4105CSU	acyl-Coa dehydrogenase
HKO16_RS09505	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
HKO16_RS09510	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HKO16_RS09515	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HKO16_RS09520	ENOG4108PTX	LysR family Transcriptional regulator
HKO16_RS09525	ENOG4107Z3H	Transcriptional regulator, TetR family
HKO16_RS09550	ENOG4108Z6Z	Transcriptional regulator
HKO16_RS09560	ENOG4105NAE	bifunctional deaminase-reductase domain protein
HKO16_RS09570	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HKO16_RS09585	ENOG4105CZJ	Aldehyde dehydrogenase
HKO16_RS09605	ENOG4107EJG	GntR family transcriptional regulator
HKO16_RS09615	ENOG4108KB2	LysR family Transcriptional regulator
HKO16_RS09620	ENOG4105DTQ	mandelate racemase muconate lactonizing
HKO16_RS09625	ENOG4105NN7	muconolactone delta-isomerase
HKO16_RS09635	ENOG4107QP7	CoA-transferase subunit A
HKO16_RS09640	ENOG4107QNJ	CoA-transferase subunit B
HKO16_RS09645	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS09650	ENOG4105F2Z	3-oxoadipate enol-lactonase
HKO16_RS09660	ENOG4105C26	Dehydrogenase
HKO16_RS09670	ENOG4105F11	amine oxidase
HKO16_RS09690	ENOG4105CHR	reductase
HKO16_RS09700	ENOG4105FUY	alpha subunit
HKO16_RS09720	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HKO16_RS09730	ENOG4105DNH	Major Facilitator
HKO16_RS09755	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS09760	ENOG4108PTX	LysR family Transcriptional regulator
HKO16_RS09765	ENOG4107HP6	Transcriptional regulator
HKO16_RS09780	ENOG4105MD1	YeeE YedE family protein
HKO16_RS09790	ENOG4105DZG	Dehydrogenase
HKO16_RS09795	ENOG4105TW1	Carbohydrate-selective porin OprB
HKO16_RS09800	ENOG4106JPM	3-dehydroshikimate dehydratase
HKO16_RS09805	ENOG4105FF2	Type I DHQase
HKO16_RS09810	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
HKO16_RS09815	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
HKO16_RS09820	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
HKO16_RS09825	ENOG4105D2S	major facilitator superfamily
HKO16_RS09830	ENOG4105F2Z	3-oxoadipate enol-lactonase
HKO16_RS09835	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
HKO16_RS09840	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS09845	ENOG4107QNJ	CoA-transferase subunit B
HKO16_RS09850	ENOG4107QP7	CoA-transferase subunit A
HKO16_RS09860	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HKO16_RS09865	ENOG4107VMU	Membrane
HKO16_RS09910	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HKO16_RS09925	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HKO16_RS09935	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HKO16_RS09940	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HKO16_RS09970	ENOG4105C7B	Threonine dehydratase
HKO16_RS09980	ENOG4105CZN	Potassium uptake protein
HKO16_RS09985	ENOG4105HDD	phospholipase
HKO16_RS09995	ENOG4105E0K	tonB-dependent siderophore receptor
HKO16_RS10010	ENOG4105PV3	Inner membrane protein yqiJ
HKO16_RS10020	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HKO16_RS10025	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HKO16_RS10045	ENOG41068P6	UPF0319 protein
HKO16_RS10055	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKO16_RS10080	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HKO16_RS10085	ENOG4105C8Y	Acetylornithine aminotransferase
HKO16_RS10090	ENOG4105M2J	Glutaredoxin
HKO16_RS10100	ENOG4105CC0	LysR family Transcriptional regulator
HKO16_RS10105	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HKO16_RS10110	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
HKO16_RS10135	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HKO16_RS10140	ENOG4105DE4	1-phosphofructokinase
HKO16_RS10145	ENOG4105DM4	PTS System
HKO16_RS10160	ENOG4105BZU	Histidine kinase
HKO16_RS10170	ENOG4105D8V	Glucose sorbosone dehydrogenase
HKO16_RS10175	ENOG4108RAV	Conserved protein
HKO16_RS10180	ENOG4105CHH	sulfate transporter
HKO16_RS10195	ENOG4105C85	amino acid
HKO16_RS10205	ENOG4105F7P	transcriptional regulator AsnC family
HKO16_RS10230	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
HKO16_RS10235	ENOG4105VEJ	Heat shock protein
HKO16_RS10245	ENOG4105Y3E	Modulates RecA activity (By similarity)
HKO16_RS10260	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HKO16_RS10280	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HKO16_RS10285	ENOG4105DZP	Membrane-associated zinc metalloprotease
HKO16_RS10295	ENOG4105KNE	Phosphatidate cytidylyltransferase
HKO16_RS10300	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HKO16_RS10325	ENOG4105CUX	Signal transduction histidine kinase
HKO16_RS10330	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HKO16_RS10385	ENOG4105CMR	udp-glucose 4-epimerase
HKO16_RS10390	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
HKO16_RS10410	ENOG4105T38	integral membrane protein
HKO16_RS10415	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKO16_RS10425	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HKO16_RS10430	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HKO16_RS10465	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HKO16_RS10470	ENOG4107QZF	nitrite reductase NADPH large subunit
HKO16_RS10480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HKO16_RS10505	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HKO16_RS10510	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HKO16_RS10520	ENOG4105D8G	Major Facilitator superfamily
HKO16_RS10535	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HKO16_RS10600	ENOG4105UPP	uncharacterized protein ydcA
HKO16_RS10750	ENOG4105WXW	Antirepressor
HKO16_RS10895	ENOG4105CBC	glutamate synthase
HKO16_RS10925	ENOG4105C0A	alcohol dehydrogenase
HKO16_RS10935	ENOG4105HSS	phospholipase C
HKO16_RS10940	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HKO16_RS10965	ENOG4105CHR	reductase
HKO16_RS10970	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS10980	ENOG4105C5Q	Transcriptional regulator
HKO16_RS10990	ENOG4108NIW	Leucine export protein LeuE
HKO16_RS10995	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS11000	ENOG4105DKK	Benzoate
HKO16_RS11010	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
HKO16_RS11035	ENOG41081QV	Universal stress protein
HKO16_RS11040	ENOG4105C5H	ABC transporter
HKO16_RS11060	ENOG4105CNM	Receptor
HKO16_RS11090	ENOG4105CUY	Mechanosensitive ion channel
HKO16_RS11100	ENOG4105R8C	Transcriptional regulator
HKO16_RS11110	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS11115	ENOG4105G7T	Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity)
HKO16_RS11140	ENOG4108D1K	outer membrane usher protein
HKO16_RS11155	ENOG4105CD8	aminopeptidase N
HKO16_RS11180	ENOG4107QUV	Domain protein
HKO16_RS11185	ENOG4105C0A	alcohol dehydrogenase
HKO16_RS11195	ENOG4107RR1	TRANSCRIPTIONal
HKO16_RS11205	ENOG4107R55	ethanolamine transporter
HKO16_RS11210	ENOG4105CPD	ethanolamine ammonia-lyase
HKO16_RS11215	ENOG4107FQ9	ethanolamine ammonia-lyase
HKO16_RS11220	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HKO16_RS11225	ENOG4105CX6	glutaminyL-tRNA synthetase
HKO16_RS11245	ENOG4108RCM	Nitroreductase
HKO16_RS11250	ENOG4108TZV	Membrane
HKO16_RS11255	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HKO16_RS11265	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HKO16_RS11270	ENOG4105K8N	protein family UPF0079, ATPase
HKO16_RS11305	ENOG4105DZ2	Transcriptional regulator
HKO16_RS11320	ENOG4105F27	Major Facilitator
HKO16_RS11325	ENOG4105EYW	Ion transport protein
HKO16_RS11335	ENOG4107QIJ	Aconitate hydratase 2
HKO16_RS11350	ENOG4105CFU	surface antigen
HKO16_RS11355	ENOG4107S74	Lysophospholipid transporter LplT
HKO16_RS11370	ENOG4105CFQ	glutamine synthetase
HKO16_RS11375	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
HKO16_RS11380	ENOG4105C08	Histidine kinase
HKO16_RS11385	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
HKO16_RS11390	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HKO16_RS11395	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
HKO16_RS11405	ENOG4105KRF	dihydroneopterin aldolase
HKO16_RS11415	ENOG4105D06	uba thif-type nad fad binding protein
HKO16_RS11420	ENOG4108MEJ	flavin reductase domain protein
HKO16_RS11430	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS11445	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HKO16_RS11460	ENOG4105CC0	LysR family Transcriptional regulator
HKO16_RS11475	ENOG4105DEN	Luciferase family
HKO16_RS11490	ENOG4105CND	Glycosyl transferase, family 2
HKO16_RS11495	ENOG4107BJW	polysaccharide deacetylase
HKO16_RS11520	ENOG4105E2S	oxidase) subunit II
HKO16_RS11525	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HKO16_RS11530	ENOG4105CCU	oxidase (Subunit III)
HKO16_RS11535	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
HKO16_RS11560	ENOG4105CDU	Replicative dna helicase
HKO16_RS11565	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HKO16_RS11615	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
HKO16_RS11620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HKO16_RS11625	ENOG4105C12	Phosphoribosylglycinamide synthetase
HKO16_RS11635	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
HKO16_RS11640	ENOG4108UMI	ABC transporter, permease
HKO16_RS11645	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HKO16_RS11655	ENOG4105CK2	sodium dicarboxylate symporter
HKO16_RS11700	ENOG4105DY2	Paraquat-inducible protein b
HKO16_RS11705	ENOG4105F1S	paraquat-inducible protein a
HKO16_RS11740	ENOG4105CSH	Transporter
HKO16_RS11790	ENOG4105JXH	GntR family transcriptional regulator
HKO16_RS11800	ENOG4105D6U	Sodium Glutamate Symporter
HKO16_RS11830	ENOG4105H4F	exported protein
HKO16_RS11865	ENOG4105C26	Dehydrogenase
HKO16_RS11870	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HKO16_RS11875	ENOG4105EVZ	LysR family transcriptional regulator
HKO16_RS11900	ENOG4105D9P	serine threonine protein kinase
HKO16_RS11930	ENOG4105KTH	gatB Yqey
HKO16_RS11935	ENOG4105ERG	peptidase m48, ste24p
HKO16_RS11940	ENOG4105C5I	Dehydrogenase
HKO16_RS11955	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HKO16_RS11990	ENOG41069NU	Nitroreductase
HKO16_RS12000	ENOG4105C1J	atp-dependent rna helicase
HKO16_RS12005	ENOG4105VEQ	Cold shock protein
HKO16_RS12015	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HKO16_RS12020	ENOG4105M08	Membrane
HKO16_RS12050	ENOG4105CYB	regulatoR
HKO16_RS12055	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HKO16_RS12060	ENOG4105E0Y	RtcB Protein
HKO16_RS12080	ENOG4105CIN	aminoacyl-histidine dipeptidase
HKO16_RS12090	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HKO16_RS12095	ENOG4105CQC	Prephenate dehydratase
HKO16_RS12100	ENOG4105NIV	Esterase
HKO16_RS12105	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS12110	ENOG4105CK2	sodium dicarboxylate symporter
HKO16_RS12115	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HKO16_RS12120	ENOG4105VUT	cytoplasmic protein
HKO16_RS12125	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HKO16_RS12130	ENOG4105BZ4	penicillin-binding protein
HKO16_RS12140	ENOG4105M6F	mutator MutT protein
HKO16_RS12150	ENOG4105DHQ	Histidine kinase
HKO16_RS12155	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HKO16_RS12165	ENOG4107QHF	type ii secretion system protein e
HKO16_RS12175	ENOG4108R96	Methyltransferase, YaeB family
HKO16_RS12180	ENOG4105DP0	ferredoxin-NADP reductase
HKO16_RS12185	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HKO16_RS12190	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKO16_RS12195	ENOG4105CFP	Peptidase U32
HKO16_RS12200	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HKO16_RS12210	ENOG4108JEH	abc transporter atp-binding protein
HKO16_RS12215	ENOG4106YG3	ABC transporter
HKO16_RS12220	ENOG4105DSP	amino acid AbC transporter
HKO16_RS12225	ENOG4105E89	ABC transporter
HKO16_RS12235	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
HKO16_RS12245	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HKO16_RS12280	ENOG4105DA5	(ABC) transporter
HKO16_RS12285	ENOG4105E3A	(ABC) transporter
HKO16_RS12300	ENOG4105CNI	cell division protein FtsW
HKO16_RS12305	ENOG4105CVE	Lytic murein transglycosylase
HKO16_RS12345	ENOG4105CE9	30S ribosomal protein S2
HKO16_RS12350	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HKO16_RS12360	ENOG4107RNU	major facilitator superfamily MFS_1
HKO16_RS12370	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
HKO16_RS12375	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HKO16_RS12380	ENOG4107QPN	acyl-Coa dehydrogenase
HKO16_RS12395	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HKO16_RS12400	ENOG4105SYT	Methylenetetrahydrofolate reductase
HKO16_RS12405	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HKO16_RS12410	ENOG4105BZU	Histidine kinase
HKO16_RS12415	ENOG4105C6K	Malic enzyme
HKO16_RS12425	ENOG4105C0H	protease
HKO16_RS12430	ENOG4107QNR	UPF0135 protein
HKO16_RS12435	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HKO16_RS12470	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HKO16_RS12485	ENOG4105DUX	Transporter
HKO16_RS12495	ENOG4105DDQ	anthranilate synthase
HKO16_RS12500	ENOG4105CD8	aminopeptidase N
HKO16_RS12530	ENOG4105C7W	Xanthine dehydrogenase
HKO16_RS12540	ENOG4105EUJ	GTP cyclohydrolase i
HKO16_RS12560	ENOG4105NX3	Membrane
HKO16_RS12595	ENOG4105BZ1	(ABC) transporter
HKO16_RS12605	ENOG4105WQI	isochorismatase
HKO16_RS12610	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HKO16_RS12615	ENOG4105C0W	non-ribosomal peptide synthetase
HKO16_RS12635	ENOG4108IPW	abc transporter atp-binding protein
HKO16_RS12650	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS12665	ENOG4105WWK	YheO domain protein
HKO16_RS12675	ENOG4105C2I	pirin domain protein
HKO16_RS12725	ENOG4105D74	hydrolase
HKO16_RS12730	ENOG4107RN6	Monooxygenase
HKO16_RS12740	ENOG4105CR8	Transcriptional regulator
HKO16_RS12745	ENOG4105CHJ	isochorismatase hydrolase
HKO16_RS12785	ENOG4105VCD	cytoplasmic protein
HKO16_RS12790	ENOG4105D22	carbon starvation protein
HKO16_RS12800	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HKO16_RS12810	ENOG41066DG	(EAL) domain protein
HKO16_RS12820	ENOG4105DHU	Bile acid
HKO16_RS12835	ENOG4105DAN	ATP-dependent protease
HKO16_RS12840	ENOG4105EJC	lysr family transcriptional regulator
HKO16_RS12845	ENOG4108K5P	(LipO)protein
HKO16_RS12865	ENOG4105DZ1	carboxypeptidase
HKO16_RS12870	ENOG4108Z0R	Transferase
HKO16_RS12890	ENOG4107QTF	adenylosuccinate lyase
HKO16_RS12905	ENOG4105ERU	peptidase
HKO16_RS12910	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HKO16_RS12920	ENOG4105C8U	phosphate abc transporter
HKO16_RS12925	ENOG4105CVA	phosphate
HKO16_RS12930	ENOG4105C85	amino acid
HKO16_RS12935	ENOG4107RA9	decarboxylase
HKO16_RS12940	ENOG4105F7P	transcriptional regulator AsnC family
HKO16_RS12950	ENOG4105DY8	decarboxylase
HKO16_RS12955	ENOG4108JPW	Aminotransferase
HKO16_RS12970	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HKO16_RS12980	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HKO16_RS12995	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
HKO16_RS13000	ENOG4105D3G	Pseudouridine synthase
HKO16_RS13015	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HKO16_RS13045	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HKO16_RS13050	ENOG4108ETY	sodium dicarboxylate symporter
HKO16_RS13055	ENOG4105EGI	Transcriptional regulator
HKO16_RS13060	ENOG4105CBP	Major Facilitator
HKO16_RS13085	ENOG4108R99	pseudouridine synthase
HKO16_RS13090	ENOG4105E9K	Isocitrate dehydrogenase
HKO16_RS13100	ENOG4105DZ1	carboxypeptidase
HKO16_RS13105	ENOG4105CEP	NADH dehydrogenase
HKO16_RS13110	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HKO16_RS13115	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HKO16_RS13130	ENOG4107R8N	Glycosyl transferase, family 2
HKO16_RS13160	ENOG4105EA8	2-Nitropropane dioxygenase
HKO16_RS13165	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HKO16_RS13170	ENOG4107QS8	(LipO)protein
HKO16_RS13205	ENOG4105DTR	rard protein
HKO16_RS13215	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HKO16_RS13225	ENOG4105BZU	Histidine kinase
HKO16_RS13245	ENOG4105F7F	Chaperone
HKO16_RS13275	ENOG4105EMU	Dehydrogenase
HKO16_RS13280	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
HKO16_RS13285	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HKO16_RS13290	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HKO16_RS13300	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HKO16_RS13315	ENOG4105C3F	Signal peptidase i
HKO16_RS13325	ENOG41068WN	
HKO16_RS13335	ENOG4105C0H	protease
HKO16_RS13340	ENOG4108IYU	L-aspartate oxidase
HKO16_RS13355	ENOG4105HHA	aminodeoxychorismate lyase
HKO16_RS13360	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
HKO16_RS13365	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HKO16_RS13375	ENOG4108I5D	sulfate abc transporter
HKO16_RS13385	ENOG4108IJ6	ABC transporter
HKO16_RS13390	ENOG4107R11	Transcriptional regulator
HKO16_RS13405	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HKO16_RS13410	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HKO16_RS13425	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKO16_RS13440	ENOG4108UKI	Enoyl-CoA hydratase
HKO16_RS13510	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
HKO16_RS13515	ENOG4108JJA	ABC, transporter
HKO16_RS13520	ENOG4107QI1	Mate efflux family protein
HKO16_RS13560	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HKO16_RS13565	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HKO16_RS13570	ENOG4108IQC	2,3-dihydroxybenzoate-AMP ligase
HKO16_RS13575	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS13580	ENOG4105C0W	non-ribosomal peptide synthetase
HKO16_RS13585	ENOG4105C0W	non-ribosomal peptide synthetase
HKO16_RS13590	ENOG4105X17	23-dihydro-2,3-dihydroxybenzoate dehydrogenase
HKO16_RS13595	ENOG4105WQI	isochorismatase
HKO16_RS13600	ENOG4105E4F	Isochorismate synthase
HKO16_RS13625	ENOG4108ETH	Formylglycinamide ribotide synthetase
HKO16_RS13645	ENOG4105CH2	amidohydrolase
HKO16_RS13650	ENOG4107YD3	Thioesterase
HKO16_RS13655	ENOG4105E02	MotA TolQ exbB proton channel
HKO16_RS13660	ENOG4105M8F	Biopolymer transport protein exbD tolR
HKO16_RS13670	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HKO16_RS13675	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HKO16_RS13725	ENOG4105C02	permease
HKO16_RS13735	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HKO16_RS13740	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HKO16_RS13745	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HKO16_RS13755	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HKO16_RS13760	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HKO16_RS13765	ENOG4105D60	lipoprotein releasing system transmembrane protein
HKO16_RS13800	ENOG4107KET	secretion protein, HlyD family
HKO16_RS13835	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKO16_RS13840	ENOG4105C10	Electron transfer flavoprotein
HKO16_RS13845	ENOG4105BZJ	Electron transfer flavoprotein
HKO16_RS13850	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKO16_RS13855	ENOG4105N14	lysine exporter protein LysE YggA
HKO16_RS13865	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HKO16_RS13875	ENOG4105C85	amino acid
HKO16_RS13880	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HKO16_RS13890	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HKO16_RS13905	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
HKO16_RS13910	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
HKO16_RS13915	ENOG4105BZW	Glycerate kinase
HKO16_RS13985	ENOG4105YCT	UPF0386 protein
HKO16_RS13995	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS14010	ENOG4108RRZ	Transcription elongation factor GreB
HKO16_RS14030	ENOG4105E4C	Lytic transglycosylase catalytic
HKO16_RS14045	ENOG4105BZS	acriflavin resistance protein
HKO16_RS14050	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
HKO16_RS14060	ENOG41080IJ	Diacylglycerol kinase
HKO16_RS14075	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HKO16_RS14090	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HKO16_RS14095	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HKO16_RS14100	ENOG4105CSH	Transporter
HKO16_RS14150	ENOG4105EEI	dihydropteroate synthase
HKO16_RS14155	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HKO16_RS14165	ENOG4105HBR	Rna-binding protein
HKO16_RS14180	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HKO16_RS14185	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HKO16_RS14195	ENOG4108IG5	Transcriptional regulator
HKO16_RS14200	ENOG4108UQ8	endoribonuclease L-psp
HKO16_RS14210	ENOG41080TK	Universal stress protein
HKO16_RS14225	ENOG4105PNM	synthesis protein
HKO16_RS14240	ENOG4105EEQ	Na H antiporter
HKO16_RS14245	ENOG4105CGZ	zinc metallopeptidase
HKO16_RS14250	ENOG4105CKW	Inner membrane protein yedI
HKO16_RS14260	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HKO16_RS14270	ENOG4107QN2	dihydrolipoyl dehydrogenase
HKO16_RS14275	ENOG4105C7S	Dehydrogenase
HKO16_RS14280	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HKO16_RS14295	ENOG4105E33	succinate dehydrogenase
HKO16_RS14305	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
HKO16_RS14310	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
HKO16_RS14345	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HKO16_RS14350	ENOG41084BA	UPF0250 protein
HKO16_RS14355	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HKO16_RS14370	ENOG4105CUB	amino acid
HKO16_RS14380	ENOG4105KVH	Transcriptional regulator
HKO16_RS14385	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HKO16_RS14390	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HKO16_RS14405	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HKO16_RS14435	ENOG410841Q	phosphoesterase PA-phosphatase related protein
HKO16_RS14440	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HKO16_RS14445	ENOG4105BZS	acriflavin resistance protein
HKO16_RS14450	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HKO16_RS14455	ENOG4105K8R	UPF0145 protein
HKO16_RS14460	ENOG4105K8R	UPF0145 protein
HKO16_RS14480	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HKO16_RS14500	ENOG4108M0I	Transcriptional regulator
HKO16_RS14515	ENOG4105DHQ	Histidine kinase
HKO16_RS14520	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HKO16_RS14525	ENOG4105DIJ	Phosphoethanolamine transferase
HKO16_RS14545	ENOG4105D78	K07001 NTE family protein
HKO16_RS14560	ENOG4105MSB	protein, conserved in bacteria
HKO16_RS14565	ENOG4105CTB	Polyprenyl synthetase
HKO16_RS14570	ENOG4105C7F	AcnD-accessory protein PrpF
HKO16_RS14575	ENOG4105C85	amino acid
HKO16_RS14595	ENOG4105CF7	AraC family transcriptional regulator
HKO16_RS14620	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HKO16_RS14630	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HKO16_RS14640	ENOG4105D8T	Acyltransferase
HKO16_RS14650	ENOG4105C03	ribonuclease
HKO16_RS14655	ENOG4108Z03	MAF-like protein
HKO16_RS14660	ENOG4105VQ7	Rod shape-determining protein MreD
HKO16_RS14665	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HKO16_RS14675	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HKO16_RS14685	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HKO16_RS14710	ENOG4105C9K	Endothelin-converting enzyme 1
HKO16_RS14720	ENOG4105C7B	Threonine dehydratase
HKO16_RS14725	ENOG4105D78	K07001 NTE family protein
HKO16_RS14730	ENOG4105BZG	amino acid carrier protein
HKO16_RS14750	ENOG4105C2C	drug resistance transporter, Bcr CflA
HKO16_RS14755	ENOG4105EM2	membrane
HKO16_RS14805	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HKO16_RS14810	ENOG4105WD1	Membrane
HKO16_RS14820	ENOG4107PEH	Entericidin EcnA/B family
HKO16_RS14835	ENOG4105CBS	Chea signal transduction histidine kinase
HKO16_RS14840	ENOG4105C8Q	Methyl-accepting chemotaxis
HKO16_RS14845	ENOG4108ZGA	chew protein
HKO16_RS14850	ENOG4105M3Z	response regulator
HKO16_RS14855	ENOG4108UNF	response regulator
HKO16_RS14880	ENOG4105KWI	UPF0339 protein
HKO16_RS14885	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
HKO16_RS14890	ENOG4105K78	MarR family Transcriptional regulator
HKO16_RS14900	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HKO16_RS14905	ENOG4105T95	Thiol disulfide interChange protein
HKO16_RS14920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HKO16_RS14925	ENOG4105CHB	tonB-dependent Receptor
HKO16_RS14930	ENOG4108VX5	3-methyladenine DNA glycosylase
HKO16_RS14940	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HKO16_RS14955	ENOG4105CI3	gtp-binding protein typa
HKO16_RS14960	ENOG4105C2W	permease
HKO16_RS14970	ENOG4108IQI	permease
HKO16_RS14975	ENOG4105E0Y	RtcB Protein
HKO16_RS14995	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS15005	ENOG410814C	multidrug resistance protein
HKO16_RS15015	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HKO16_RS15020	ENOG4105DZG	Dehydrogenase
HKO16_RS15025	ENOG4105TW1	Carbohydrate-selective porin OprB
HKO16_RS15035	ENOG4108R6W	Transcriptional regulator, ARAC family
HKO16_RS15040	ENOG4105CHU	acetyl-coa acetyltransferase
HKO16_RS15060	ENOG41082BV	acetyltransferase
HKO16_RS15070	ENOG4108UT2	hemolysin iii
HKO16_RS15075	ENOG4105CSH	Transporter
HKO16_RS15090	ENOG4105D3R	alkyl hydroperoxide reductase
HKO16_RS15110	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HKO16_RS15155	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HKO16_RS15160	ENOG4108WBT	adenosyltransferase
HKO16_RS15180	ENOG4105CNG	UPF0061 protein
HKO16_RS15185	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
HKO16_RS15190	ENOG4105EB3	Histidine kinase
HKO16_RS15200	ENOG4105CSU	acyl-Coa dehydrogenase
HKO16_RS15205	ENOG4105CSU	acyl-Coa dehydrogenase
HKO16_RS15210	ENOG4108VY7	phosphate-starvation-inducible protein PsiE
HKO16_RS15230	ENOG4105UGU	tonB-dependent Receptor
HKO16_RS15255	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
HKO16_RS15270	ENOG4108PQP	glycosyl transferase group 1
HKO16_RS15280	ENOG4107BJW	polysaccharide deacetylase
HKO16_RS15295	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HKO16_RS15300	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HKO16_RS15305	ENOG4105BZU	Histidine kinase
HKO16_RS15320	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HKO16_RS15375	ENOG4105VIE	preprotein translocase, subunit YajC
HKO16_RS15380	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HKO16_RS15385	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HKO16_RS15390	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HKO16_RS15400	ENOG4105FFC	UPF0187 protein
HKO16_RS15405	ENOG4105DB7	PHP domain protein
HKO16_RS15415	ENOG4105K9H	YciI-like protein
HKO16_RS15440	ENOG4105DFP	Integrase
HKO16_RS15480	ENOG4105CE1	Ferrous iron transport protein b
HKO16_RS15490	ENOG4108IJF	Heavy metal efflux pump, CzcA
HKO16_RS15515	ENOG4105E3B	Multicopper oxidase
HKO16_RS15530	ENOG4105GR3	Histidine kinase
HKO16_RS15610	ENOG4105XWI	UPF0304 protein
HKO16_RS15645	ENOG4105NAU	thioesterase Superfamily protein
HKO16_RS15655	ENOG4107U2T	alpha beta
HKO16_RS15705	ENOG4108KHX	Diguanylate cyclase
HKO16_RS15710	ENOG4105UYK	outer membrane protein a
HKO16_RS15720	ENOG4107RZC	phospholipase d
HKO16_RS15730	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HKO16_RS15750	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HKO16_RS15755	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HKO16_RS15760	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HKO16_RS15770	ENOG4108UJD	30S ribosomal protein S9
HKO16_RS15775	ENOG4107MKT	Stringent starvation protein a
HKO16_RS15780	ENOG4105KB2	stringent starvation protein b
HKO16_RS15800	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS15805	ENOG4107QX3	carboxylase
HKO16_RS15820	ENOG4108RZE	Tetr family transcriptional regulator
HKO16_RS15825	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS15870	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HKO16_RS15875	ENOG4105D6S	protein involved in catabolism of external DNA
HKO16_RS15905	ENOG4105E4C	Lytic transglycosylase catalytic
HKO16_RS15915	ENOG4105C9A	Phoh family
HKO16_RS15945	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HKO16_RS15950	ENOG4107S2Z	UPF0761 membrane protein
HKO16_RS15960	ENOG4108K2B	transcriptional regulator
HKO16_RS15965	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HKO16_RS16010	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HKO16_RS16015	ENOG4105DGW	oligopeptidase A
HKO16_RS16020	ENOG4105VKU	nucleicacid-binding protein
HKO16_RS16055	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS16095	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HKO16_RS16205	ENOG41089BK	Glutamine amido-transferase
HKO16_RS16215	ENOG4105D7A	ATP-binding protein
HKO16_RS16230	ENOG4105KPV	Transcriptional regulator
HKO16_RS16245	ENOG4105CK2	sodium dicarboxylate symporter
HKO16_RS16250	ENOG4105C29	acyl-CoA thioesterase
HKO16_RS16270	ENOG4105CB5	ATP-dependent DNA helicase recG
HKO16_RS16275	ENOG4105MJ2	Competence protein
HKO16_RS16285	ENOG4108URH	decarboxylase
HKO16_RS16290	ENOG4105D7N	magnesium and cobalt transport protein CorA
HKO16_RS16300	ENOG4105E3I	toluene tolerance
HKO16_RS16310	ENOG4105CY3	ABC transporter, permease
HKO16_RS16315	ENOG4105DHJ	ABC, transporter
HKO16_RS16325	ENOG4105C1J	atp-dependent rna helicase
HKO16_RS16330	ENOG4105ECY	inositol monophosphatase
HKO16_RS16345	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HKO16_RS16360	ENOG4105CSU	acyl-Coa dehydrogenase
HKO16_RS16370	ENOG41067S9	phage shock protein C, PspC
HKO16_RS16375	ENOG4105W87	Cbs domain
HKO16_RS16465	ENOG4105C26	Dehydrogenase
HKO16_RS16475	ENOG4105C8Y	Acetylornithine aminotransferase
HKO16_RS16480	ENOG4105D82	Glutamate dehydrogenase
HKO16_RS16485	ENOG4108IQI	permease
HKO16_RS16515	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HKO16_RS16520	ENOG4105IPI	Membrane
HKO16_RS16525	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HKO16_RS16530	ENOG4105EM2	membrane
HKO16_RS16535	ENOG4107QF7	multi-drug
HKO16_RS16545	ENOG4105NF4	modulator of drug activity
HKO16_RS16550	ENOG4105VRH	Antibiotic biosynthesis monooxygenase
HKO16_RS16560	ENOG4105CQB	FAD linked oxidase domain protein
HKO16_RS16565	ENOG4108JQ1	Dehydrogenase
HKO16_RS16590	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HKO16_RS16595	ENOG4105MGK	May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity)
HKO16_RS16600	ENOG4107IFA	Lipase (EC 3.1.1.3)
HKO16_RS16615	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HKO16_RS16665	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HKO16_RS16680	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HKO16_RS16685	ENOG4105KME	endoribonuclease L-psp
HKO16_RS16695	ENOG4108UQY	Iron-storage protein
HKO16_RS16700	ENOG4108YSG	O-Antigen polymerase
HKO16_RS16715	ENOG4105HA9	of methanol dehydrogenase type
HKO16_RS16720	ENOG4108V0P	LemA family
HKO16_RS16730	ENOG4105BZ8	glutamate synthase
HKO16_RS16735	ENOG4105CBC	glutamate synthase
HKO16_RS16755	ENOG4105E4G	Type IV pilus
HKO16_RS16780	ENOG4108JQC	penicillin-binding protein 1A
HKO16_RS16785	ENOG4105DHI	Methyltransferase
HKO16_RS16800	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HKO16_RS16805	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HKO16_RS16810	ENOG4105CJN	penicillin-binding protein
HKO16_RS16825	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
HKO16_RS16850	ENOG4108IQI	permease
HKO16_RS16915	ENOG4105C5H	ABC transporter
HKO16_RS16940	ENOG4105PDP	Short chain dehydrogenase
HKO16_RS16945	ENOG4105CHH	sulfate transporter
HKO16_RS16950	ENOG4105BZM	domain protein
HKO16_RS16960	ENOG4105E0F	Histidine kinase
HKO16_RS16970	ENOG4105CYC	Transferase
HKO16_RS16975	ENOG4108R6G	acetyltransferase
HKO16_RS17000	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HKO16_RS17030	ENOG41061CK	Antibiotic biosynthesis monooxygenase
HKO16_RS17045	ENOG4105CUV	Homoserine Kinase
HKO16_RS17100	ENOG4108UQN	AraC family transcriptional regulator
HKO16_RS17105	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
HKO16_RS17125	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
HKO16_RS17130	ENOG4105KVH	Transcriptional regulator
HKO16_RS17160	ENOG4105KVH	Transcriptional regulator
HKO16_RS17180	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
HKO16_RS17205	ENOG4106NZI	LysR family Transcriptional regulator
HKO16_RS17210	ENOG4105D94	Major Facilitator Superfamily
HKO16_RS17245	ENOG4105EUB	pirin domain protein
HKO16_RS17250	ENOG4105CHJ	isochorismatase hydrolase
HKO16_RS17260	ENOG4105C26	Dehydrogenase
HKO16_RS17265	ENOG4108JPW	Aminotransferase
HKO16_RS17275	ENOG4105C85	amino acid
HKO16_RS17285	ENOG4108UMN	azlc family
HKO16_RS17295	ENOG4108UUM	single-stranded DNA-binding protein
HKO16_RS17300	ENOG4107RDB	Major Facilitator
HKO16_RS17310	ENOG4105DWF	phosphomethylpyrimidine kinase
HKO16_RS17315	ENOG4105RA2	Membrane
HKO16_RS17325	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HKO16_RS17330	ENOG4108WUH	Transcriptional regulator, TetR family
HKO16_RS17335	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HKO16_RS17340	ENOG4105BZU	Histidine kinase
HKO16_RS17350	ENOG4105C94	Transporter
HKO16_RS17360	ENOG4107QN1	sodium solute
HKO16_RS17365	ENOG41062QD	Membrane
HKO16_RS17370	ENOG4105BZU	Histidine kinase
HKO16_RS17385	ENOG4108UZX	fmn reductase
HKO16_RS17390	ENOG4105FBW	Monooxygenase
HKO16_RS17400	ENOG4108W2Y	isochorismatase
HKO16_RS17405	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HKO16_RS17415	ENOG4105D64	Mechanosensitive ion channel
HKO16_RS17425	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HKO16_RS17430	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HKO16_RS17450	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HKO16_RS17465	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HKO16_RS17480	ENOG4105E0K	tonB-dependent siderophore receptor
HKO16_RS17495	ENOG4107QSN	dihydrolipoamide acetyltransferase
HKO16_RS17500	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HKO16_RS17505	ENOG41063SB	peptidase
HKO16_RS17520	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HKO16_RS17525	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HKO16_RS17530	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HKO16_RS17550	ENOG4105D7Z	glutathione synthase
HKO16_RS17575	ENOG4105CGK	Exodeoxyribonuclease III
HKO16_RS17580	ENOG4105KUZ	arsenate reductase
HKO16_RS17595	ENOG4105BZU	Histidine kinase
HKO16_RS17600	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HKO16_RS17630	ENOG41084YZ	Hydrolase
HKO16_RS17645	ENOG41061H0	Monooxygenase
HKO16_RS17655	ENOG4108Z2U	ureidoglycolate hydrolase
HKO16_RS17660	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKO16_RS17665	ENOG4105IPS	esterase
HKO16_RS17775	ENOG4105D6J	arsenicaL-resistance protein
HKO16_RS17860	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HKO16_RS17890	ENOG4105CHH	sulfate transporter
HKO16_RS17945	ENOG4105C0P	Mg chelatase subunit ChlI
HKO16_RS17950	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HKO16_RS17960	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HKO16_RS17970	ENOG41090KI	Outer membrane porin
HKO16_RS17975	ENOG4105F0N	pyrophosphate phospho-hydrolase
HKO16_RS17990	ENOG4105CEY	Amp-dependent synthetase and ligase
HKO16_RS17995	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HKO16_RS18000	ENOG41079KZ	Major Facilitator Superfamily
HKO16_RS18005	ENOG4105EN6	Membrane
HKO16_RS18010	ENOG4105K5B	UPF0225 protein
HKO16_RS18015	ENOG4105EE5	Membrane protein terC
HKO16_RS18020	ENOG4108URH	decarboxylase
HKO16_RS18025	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HKO16_RS18035	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HKO16_RS18050	ENOG4105CCT	upf0313 protein
HKO16_RS18070	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HKO16_RS18080	ENOG4105C6T	cysteine synthase
HKO16_RS18115	ENOG4105Y7M	Transcriptional regulator, TetR family
HKO16_RS18150	ENOG4105C79	DNA protecting protein DprA
HKO16_RS18165	ENOG4108IND	Tetr family transcriptional regulator
HKO16_RS18170	ENOG4107RTG	Major Facilitator superfamily
HKO16_RS18180	ENOG4108V06	Glutathione peroxidase
HKO16_RS18190	ENOG41090VV	Protein of unknown function (DUF2846)
HKO16_RS18250	ENOG4105FDK	ABC transporter
HKO16_RS18255	ENOG4105FAV	ABC, transporter
HKO16_RS18260	ENOG410829K	Lysine exporter protein (Lyse ygga)
HKO16_RS18265	ENOG4105EZR	dyp-type peroxidase family protein
HKO16_RS18270	ENOG4107R1I	NAD-dependent malic enzyme
HKO16_RS18295	ENOG4105EUB	pirin domain protein
HKO16_RS18315	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HKO16_RS18320	ENOG4106MP8	UPF0754 membrane protein
HKO16_RS18325	ENOG4108VBZ	doxx family
HKO16_RS18330	ENOG4105DQR	SNARE associated Golgi
HKO16_RS18345	ENOG4107QJE	Chromosome Partitioning Protein
HKO16_RS18355	ENOG4107PSF	BolA-like protein
HKO16_RS18400	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS18405	ENOG4107RCI	amp-dependent synthetase and ligase
HKO16_RS18425	ENOG4105CSH	Transporter
HKO16_RS18430	ENOG4105E39	Enoyl-CoA hydratase
HKO16_RS18435	ENOG4105E39	Enoyl-CoA hydratase
HKO16_RS18440	ENOG4105C1G	acyl-Coa dehydrogenase
HKO16_RS18450	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HKO16_RS18455	ENOG4105C26	Dehydrogenase
HKO16_RS18465	ENOG4105C85	amino acid
HKO16_RS18470	ENOG4105C85	amino acid
HKO16_RS18475	ENOG4105M4H	endoribonuclease L-psp
HKO16_RS18490	ENOG4105EW9	transcriptional regulator AsnC family
HKO16_RS18515	ENOG4105D3G	Pseudouridine synthase
HKO16_RS18595	ENOG4108I0Z	Aconitate hydratase
HKO16_RS18600	ENOG4105BZN	citrate synthase
HKO16_RS18605	ENOG4105CR4	methylisocitrate lyase
HKO16_RS18610	ENOG4105DRR	Transcriptional regulator, GntR family
HKO16_RS18620	ENOG4105CGF	Aromatic amino acid aminotransferase
HKO16_RS18625	ENOG4105CXG	d-lactate dehydrogenase
HKO16_RS18635	ENOG41073TP	transcriptional regulator
HKO16_RS18640	ENOG4105DAA	L-lactate
HKO16_RS18645	ENOG4107QKV	phosphomannomutase
HKO16_RS18650	ENOG4105CMR	udp-glucose 4-epimerase
HKO16_RS18660	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HKO16_RS18665	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HKO16_RS18670	ENOG4105D3Q	Sugar transferase
HKO16_RS18675	ENOG4108RYC	glycosyltransferase
HKO16_RS18680	ENOG4105CG5	Glycosyl transferase (Group 1
HKO16_RS18695	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HKO16_RS18700	ENOG4108UW5	maltose o-acetyltransferase
HKO16_RS18710	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HKO16_RS18715	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HKO16_RS18720	ENOG4107R5Z	Oxidoreductase domain protein
HKO16_RS18725	ENOG4107QQG	Dehydrogenase
HKO16_RS18730	ENOG4105DAY	polysaccharide export protein
HKO16_RS18740	ENOG4105D75	Capsular exopolysaccharide family
HKO16_RS18745	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HKO16_RS18750	ENOG4108V1T	peptidylprolyl cis-trans isomerase
HKO16_RS18755	ENOG4105CJR	Integral membrane protein (MviN
HKO16_RS18760	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
HKO16_RS18765	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HKO16_RS18775	ENOG4105HSS	phospholipase C
HKO16_RS18805	ENOG41062JF	Transcriptional regulator
HKO16_RS18810	ENOG4108Z33	Thiol disulfide Interchange Protein
HKO16_RS18820	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HKO16_RS18825	ENOG4105UBK	short-chain dehydrogenase reductase
HKO16_RS18840	ENOG4107QZM	n-acetylglutamate synthase
HKO16_RS18845	ENOG4105GVF	(ABC) transporter
HKO16_RS18850	ENOG4105GVF	(ABC) transporter
HKO16_RS18855	ENOG4105D4R	Catalyzes the desulfonation of aliphatic sulfonates (By similarity)
HKO16_RS18860	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HKO16_RS18865	ENOG4108VM9	ABC, transporter
HKO16_RS18870	ENOG4108R86	Transcriptional regulator
HKO16_RS18875	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
HKO16_RS18885	ENOG4105DTN	riboflavin biosynthesis protein ribF
HKO16_RS18890	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HKO16_RS18900	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
HKO16_RS18940	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HKO16_RS18995	ENOG4105CVE	Lytic murein transglycosylase
HKO16_RS19000	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HKO16_RS19005	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HKO16_RS19015	ENOG4105DFU	Cell wall formation (By similarity)
HKO16_RS19025	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
HKO16_RS19030	ENOG4105DU1	integral membrane protein, terc
HKO16_RS19040	ENOG4106032	Glutathionylspermidine synthase
HKO16_RS19050	ENOG4107QUY	Guanine deaminase
HKO16_RS19055	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HKO16_RS19065	ENOG4105T95	Thiol disulfide interChange protein
HKO16_RS19070	ENOG4105PGM	cation diffusion facilitator family transporter
HKO16_RS19085	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKO16_RS19115	ENOG4105RQF	LysR family Transcriptional regulator
HKO16_RS19150	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
HKO16_RS19225	ENOG4107ZQV	short-chain dehydrogenase reductase
HKO16_RS19240	ENOG4105UGU	tonB-dependent Receptor