locus-tag	class	description
GO593_RS00025	COG3111	PFAM Bacterial OB fold (BOF) protein
GO593_RS00125	COG1610	YqeY-like protein
GO593_RS00130	COG4783	chaperone-mediated protein folding
GO593_RS00155	COG1286	toxin biosynthetic process
GO593_RS00185	COG0778	Nitroreductase
GO593_RS00195	COG0513	Belongs to the DEAD box helicase family
GO593_RS00215	COG2363	Small membrane protein
GO593_RS00245	COG1234	tRNA 3'-trailer cleavage
GO593_RS00250	COG2195	Cleaves the N-terminal amino acid of tripeptides
GO593_RS00260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GO593_RS00270	COG2819	hydrolase of the alpha beta superfamily
GO593_RS00275	COG1960	acyl-CoA dehydrogenase activity
GO593_RS00280	COG1301	dicarboxylic acid transport
GO593_RS00285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GO593_RS00290	COG3139	Protein of unknown function (DUF1315)
GO593_RS00295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GO593_RS00300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GO593_RS00310	COG0494	nUDIX hydrolase
GO593_RS00320	COG0642	Histidine kinase
GO593_RS00330	COG3111	PFAM Bacterial OB fold (BOF) protein
GO593_RS00335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GO593_RS00345	COG1720	tRNA m6t6A37 methyltransferase activity
GO593_RS00360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO593_RS00365	COG0826	peptidase U32
GO593_RS00370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO593_RS00380	COG4598	ABC transporter
GO593_RS00385	COG4160	amino acid transport
GO593_RS00390	COG4215	(ABC) transporter
GO593_RS00405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS00765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO593_RS00795	COG3617	BRO family, N-terminal domain
GO593_RS00800	COG0582	viral genome integration into host DNA
GO593_RS00805	COG1131	(ABC) transporter
GO593_RS00810	COG0842	Transport permease protein
GO593_RS00825	COG0772	Belongs to the SEDS family
GO593_RS00830	COG2951	lytic endotransglycosylase activity
GO593_RS00855	COG2207	Transcriptional regulator
GO593_RS00870	COG0052	Belongs to the universal ribosomal protein uS2 family
GO593_RS00875	COG0024	Methionine aminopeptidase
GO593_RS00885	COG2223	nitrite transmembrane transporter activity
GO593_RS00895	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO593_RS00900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GO593_RS00905	COG1960	acyl-CoA dehydrogenase activity
GO593_RS00920	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GO593_RS00925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GO593_RS00930	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO593_RS00950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO593_RS00955	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GO593_RS00960	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GO593_RS00995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GO593_RS01005	COG0174	glutamine synthetase
GO593_RS01020	COG0512	Glutamine amidotransferase of anthranilate synthase
GO593_RS01025	COG0308	aminopeptidase N
GO593_RS01055	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GO593_RS01065	COG0302	gtp cyclohydrolase
GO593_RS01085	COG3739	integral membrane protein
GO593_RS01100	COG1169	isochorismate synthase
GO593_RS01110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GO593_RS01115	COG1132	(ABC) transporter
GO593_RS01120	COG1132	(ABC) transporter
GO593_RS01135	COG3433	isochorismatase activity
GO593_RS01135	COG1535	isochorismatase
GO593_RS01140	COG1021	2,3-dihydroxybenzoate-AMP ligase
GO593_RS01145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO593_RS01155	COG4774	siderophore transport
GO593_RS01160	COG4607	ABC-type enterochelin transport system periplasmic component
GO593_RS01165	COG4604	ABC transporter, ATP-binding protein
GO593_RS01170	COG4605	iron ion homeostasis
GO593_RS01175	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO593_RS01180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO593_RS01195	COG2964	Protein conserved in bacteria
GO593_RS01205	COG1741	Belongs to the pirin family
GO593_RS01235	COG2879	small protein
GO593_RS01240	COG1966	Carbon starvation protein
GO593_RS01260	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GO593_RS01285	COG1067	ATP-dependent peptidase activity
GO593_RS01290	COG0583	DNA-binding transcription factor activity
GO593_RS01315	COG1686	Belongs to the peptidase S11 family
GO593_RS01320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GO593_RS01355	COG0616	signal peptide processing
GO593_RS01360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GO593_RS01370	COG0573	inorganic phosphate transmembrane transporter activity
GO593_RS01375	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO593_RS01380	COG1113	amino acid transport
GO593_RS01385	COG3961	Belongs to the TPP enzyme family
GO593_RS01390	COG1522	sequence-specific DNA binding
GO593_RS01400	COG0076	glutamate decarboxylase activity
GO593_RS01405	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO593_RS01420	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO593_RS01430	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO593_RS01465	COG0352	thiamine-phosphate diphosphorylase activity
GO593_RS01490	COG0612	Peptidase, M16
GO593_RS01500	COG1823	symporter activity
GO593_RS01505	COG0583	DNA-binding transcription factor activity
GO593_RS01510	COG0477	Major facilitator Superfamily
GO593_RS01535	COG1187	pseudouridine synthase activity
GO593_RS01550	COG1686	Belongs to the peptidase S11 family
GO593_RS01555	COG1252	NADH dehydrogenase
GO593_RS01565	COG0415	Belongs to the DNA photolyase family
GO593_RS01580	COG1215	transferase activity, transferring glycosyl groups
GO593_RS01610	COG2070	2-Nitropropane dioxygenase
GO593_RS01665	COG0556	nucleotide-excision repair
GO593_RS01685	COG0436	Aminotransferase
GO593_RS01695	COG0443	Heat shock 70 kDa protein
GO593_RS01725	COG4221	oxidoreductase activity
GO593_RS01735	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GO593_RS01740	COG1381	Involved in DNA repair and RecF pathway recombination
GO593_RS01750	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GO593_RS01765	COG0681	Belongs to the peptidase S26 family
GO593_RS01780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GO593_RS01800	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GO593_RS01805	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GO593_RS01810	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GO593_RS01820	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GO593_RS01825	COG4208	sulfate ABC transporter
GO593_RS01830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GO593_RS01835	COG0583	DNA-binding transcription factor activity
GO593_RS01840	COG4625	pathogenesis
GO593_RS01855	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GO593_RS01870	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GO593_RS01880	COG1056	cytidyltransferase-related domain
GO593_RS01880	COG1051	belongs to the nudix hydrolase family
GO593_RS01885	COG1024	Enoyl-CoA hydratase
GO593_RS01895	COG2814	Major facilitator Superfamily
GO593_RS01900	COG0047	phosphoribosylformylglycinamidine synthase activity
GO593_RS01900	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GO593_RS01920	COG1473	amidohydrolase
GO593_RS01925	COG0824	Thioesterase
GO593_RS01945	COG0823	Involved in the tonB-independent uptake of proteins
GO593_RS01965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO593_RS02000	COG0628	permease
GO593_RS02010	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GO593_RS02015	COG0596	Alpha beta hydrolase
GO593_RS02020	COG0616	signal peptide processing
GO593_RS02020	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GO593_RS02030	COG2333	competence protein COMEC
GO593_RS02030	COG0658	competence protein
GO593_RS02035	COG1136	(ABC) transporter
GO593_RS02040	COG4591	ABC-type transport system involved in lipoprotein release permease component
GO593_RS02070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS02090	COG0463	Glycosyl transferase, family 2
GO593_RS02120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GO593_RS02125	COG1280	lysine exporter protein (LysE YggA)
GO593_RS02130	COG2267	carboxylic ester hydrolase activity
GO593_RS02145	COG0019	diaminopimelate decarboxylase activity
GO593_RS02155	COG1113	amino acid transport
GO593_RS02170	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GO593_RS02180	COG3339	Conserved Protein
GO593_RS02185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GO593_RS02190	COG0243	molybdopterin cofactor binding
GO593_RS02195	COG1929	Belongs to the glycerate kinase type-1 family
GO593_RS02210	COG0778	Nitroreductase
GO593_RS02235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO593_RS02250	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GO593_RS02270	COG0741	lytic transglycosylase activity
GO593_RS02290	COG0584	glycerophosphoryl diester phosphodiesterase
GO593_RS02295	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO593_RS02320	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GO593_RS02325	COG1597	lipid kinase activity
GO593_RS02340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GO593_RS02345	COG0477	Major facilitator Superfamily
GO593_RS02395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GO593_RS02400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GO593_RS02425	COG0505	Belongs to the CarA family
GO593_RS02445	COG0589	response to stress
GO593_RS02460	COG2843	Capsule synthesis protein
GO593_RS02480	COG2321	neutral zinc metallopeptidase
GO593_RS02485	COG2354	Protein conserved in bacteria
GO593_RS02505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO593_RS02530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GO593_RS02535	COG1053	succinate dehydrogenase
GO593_RS02540	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GO593_RS02545	COG2009	succinate dehydrogenase
GO593_RS02585	COG2921	Belongs to the UPF0250 family
GO593_RS02590	COG0321	lipoyl(octanoyl) transferase activity
GO593_RS02605	COG0531	amino acid
GO593_RS02620	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GO593_RS02625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GO593_RS02625	COG1648	precorrin-2 dehydrogenase activity
GO593_RS02640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GO593_RS02670	COG0671	phosphoesterase, PA-phosphatase related
GO593_RS02675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS02685	COG1538	Outer membrane efflux protein
GO593_RS02690	COG0393	Putative heavy-metal-binding
GO593_RS02695	COG0393	Putative heavy-metal-binding
GO593_RS02705	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS02715	COG0525	valine-tRNA ligase activity
GO593_RS02735	COG0583	DNA-binding transcription factor activity
GO593_RS02740	COG0004	ammonium transporteR
GO593_RS02755	COG0642	Histidine kinase
GO593_RS02760	COG0745	RESPONSE REGULATOR receiver
GO593_RS02765	COG2194	sulfuric ester hydrolase activity
GO593_RS02785	COG1752	Esterase of the alpha-beta hydrolase superfamily
GO593_RS02800	COG2315	Protein conserved in bacteria
GO593_RS02805	COG0142	geranyltranstransferase activity
GO593_RS02810	COG2828	Protein conserved in bacteria
GO593_RS02815	COG1113	amino acid transport
GO593_RS02835	COG2207	Transcriptional regulator
GO593_RS02860	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO593_RS02870	COG0560	Phosphoserine phosphatase
GO593_RS02880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GO593_RS02890	COG1530	ribonuclease E activity
GO593_RS02895	COG0424	maF-like protein
GO593_RS02900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GO593_RS02905	COG1792	Involved in formation and maintenance of cell shape
GO593_RS02910	COG1077	Cell shape determining protein MreB Mrl
GO593_RS02915	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GO593_RS02925	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GO593_RS02950	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GO593_RS02955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO593_RS02960	COG1752	Esterase of the alpha-beta hydrolase superfamily
GO593_RS02965	COG1115	amino acid carrier protein
GO593_RS02985	COG2814	Major facilitator Superfamily
GO593_RS02990	COG1289	transmembrane transporter activity
GO593_RS03000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GO593_RS03040	COG1376	ErfK ybiS ycfS ynhG family protein
GO593_RS03045	COG2832	Protein of unknown function (DUF454)
GO593_RS03055	COG5510	response to toxic substance
GO593_RS03075	COG0840	transmembrane signaling receptor activity
GO593_RS03115	COG3422	double-strand break repair
GO593_RS03120	COG2824	Alkylphosphonate utilization operon protein PhnA
GO593_RS03125	COG3189	MarR family transcriptional regulator
GO593_RS03135	COG0354	folic acid binding
GO593_RS03140	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO593_RS03155	COG1902	pentaerythritol trinitrate reductase activity
GO593_RS03160	COG4772	TonB-dependent receptor
GO593_RS03165	COG2094	Belongs to the DNA glycosylase MPG family
GO593_RS03190	COG1217	gtp-binding protein TYPA
GO593_RS03195	COG2233	PERMEase
GO593_RS03205	COG0833	amino acid
GO593_RS03210	COG1690	Belongs to the RtcB family
GO593_RS03215	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GO593_RS03215	COG2885	chlorophyll binding
GO593_RS03225	COG0183	Belongs to the thiolase family
GO593_RS03245	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO593_RS03265	COG2207	Transcriptional regulator
GO593_RS03270	COG0183	Belongs to the thiolase family
GO593_RS03300	COG1272	protein, Hemolysin III
GO593_RS03305	COG0477	Major facilitator Superfamily
GO593_RS03320	COG0450	alkyl hydroperoxide reductase
GO593_RS03340	COG0285	dihydrofolate synthase activity
GO593_RS03385	COG4206	TonB-dependent receptor
GO593_RS03390	COG2096	Adenosyltransferase
GO593_RS03410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GO593_RS03415	COG0745	RESPONSE REGULATOR receiver
GO593_RS03420	COG2205	protein histidine kinase activity
GO593_RS03430	COG1960	acyl-CoA dehydrogenase activity
GO593_RS03435	COG1960	acyl-CoA dehydrogenase activity
GO593_RS03440	COG0583	DNA-binding transcription factor activity
GO593_RS03445	COG0625	glutathione transferase activity
GO593_RS03510	COG0438	transferase activity, transferring glycosyl groups
GO593_RS03515	COG0463	Glycosyl transferase, family 2
GO593_RS03520	COG0726	polysaccharide deacetylase
GO593_RS03540	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GO593_RS03545	COG2205	protein histidine kinase activity
GO593_RS03580	COG1862	Preprotein translocase
GO593_RS03590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GO593_RS03595	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GO593_RS03605	COG3781	membrane
GO593_RS03610	COG0613	PHP domain protein
GO593_RS03620	COG2350	Protein conserved in bacteria
GO593_RS03650	COG1607	acyl-coa hydrolase
GO593_RS03710	COG2199	diguanylate cyclase activity
GO593_RS03720	COG1408	metallophosphoesterase
GO593_RS03725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO593_RS03735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GO593_RS03755	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GO593_RS03760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GO593_RS03775	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO593_RS03785	COG2969	positive regulation of protein catabolic process
GO593_RS03805	COG1960	acyl-CoA dehydrogenase activity
GO593_RS03810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GO593_RS03825	COG1309	transcriptional regulator
GO593_RS03830	COG1960	acyl-CoA dehydrogenase activity
GO593_RS03875	COG1183	phosphatidylcholine synthase activity
GO593_RS03880	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GO593_RS03910	COG1196	nuclear chromosome segregation
GO593_RS03910	COG0741	lytic transglycosylase activity
GO593_RS03910	COG0739	heme binding
GO593_RS03920	COG1702	phosphate starvation-inducible protein PhoH
GO593_RS03955	COG1295	ribonuclease BN
GO593_RS03960	COG0697	spore germination
GO593_RS03965	COG2169	Transcriptional regulator
GO593_RS03970	COG0179	Fumarylacetoacetate (FAA) hydrolase
GO593_RS04015	COG0557	exoribonuclease II activity
GO593_RS04020	COG0339	signal peptide processing
GO593_RS04025	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GO593_RS04055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GO593_RS04060	COG1960	acyl-CoA dehydrogenase activity
GO593_RS04215	COG0626	cystathionine gamma-synthase activity
GO593_RS04220	COG0433	COG0433 Predicted ATPase
GO593_RS04225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO593_RS04225	COG1017	nitric oxide dioxygenase activity
GO593_RS04230	COG1959	2 iron, 2 sulfur cluster binding
GO593_RS04245	COG1301	dicarboxylic acid transport
GO593_RS04250	COG1946	Acyl-CoA thioesterase
GO593_RS04270	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GO593_RS04275	COG1040	competence protein
GO593_RS04280	COG0494	nUDIX hydrolase
GO593_RS04290	COG0598	Magnesium transport protein CorA
GO593_RS04300	COG2854	intermembrane phospholipid transfer
GO593_RS04310	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GO593_RS04315	COG1127	ABC transporter
GO593_RS04325	COG0513	Belongs to the DEAD box helicase family
GO593_RS04345	COG0408	coproporphyrinogen oxidase activity
GO593_RS04360	COG1960	acyl-CoA dehydrogenase activity
GO593_RS04370	COG1983	PspC domain protein
GO593_RS04375	COG0517	IMP dehydrogenase activity
GO593_RS04415	COG0583	DNA-binding transcription factor activity
GO593_RS04455	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS04465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO593_RS04470	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO593_RS04475	COG0833	amino acid
GO593_RS04505	COG1192	Involved in chromosome partitioning
GO593_RS04510	COG0628	permease
GO593_RS04520	COG1289	transmembrane transporter activity
GO593_RS04535	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO593_RS04540	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GO593_RS04550	COG0277	FAD linked oxidase domain protein
GO593_RS04555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GO593_RS04580	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GO593_RS04585	COG5380	lipid catabolic process
GO593_RS04605	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GO593_RS04655	COG0194	GDP metabolic process
GO593_RS04670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO593_RS04690	COG3307	-O-antigen
GO593_RS04710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GO593_RS04715	COG1704	LemA family
GO593_RS04725	COG0493	'glutamate synthase
GO593_RS04730	COG0067	glutamate synthase
GO593_RS04730	COG0070	glutamate synthase
GO593_RS04730	COG0069	glutamate synthase activity
GO593_RS04780	COG2226	methyltransferase
GO593_RS04795	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GO593_RS04800	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GO593_RS04845	COG0833	amino acid
GO593_RS04910	COG0488	(ABC) transporter
GO593_RS04915	COG2873	o-acetylhomoserine
GO593_RS04920	COG4221	oxidoreductase activity
GO593_RS04925	COG0659	secondary active sulfate transmembrane transporter activity
GO593_RS04950	COG0427	acetyl-CoA hydrolase
GO593_RS04980	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GO593_RS05020	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GO593_RS05090	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO593_RS05095	COG1733	regulation of RNA biosynthetic process
GO593_RS05125	COG0667	Aldo Keto reductase
GO593_RS05145	COG0583	DNA-binding transcription factor activity
GO593_RS05150	COG2814	Major facilitator Superfamily
GO593_RS05180	COG1335	isochorismatase
GO593_RS05190	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS05195	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GO593_RS05205	COG1113	amino acid transport
GO593_RS05215	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GO593_RS05265	COG2814	Major facilitator Superfamily
GO593_RS05275	COG0351	phosphomethylpyrimidine kinase
GO593_RS05275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GO593_RS05275	COG0352	thiamine-phosphate diphosphorylase activity
GO593_RS05295	COG1309	transcriptional regulator
GO593_RS05300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GO593_RS05315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO593_RS05325	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO593_RS05330	COG3162	membrane
GO593_RS05335	COG2205	protein histidine kinase activity
GO593_RS05335	COG2198	Histidine kinase
GO593_RS05335	COG0784	Response regulator, receiver
GO593_RS05360	COG1522	sequence-specific DNA binding
GO593_RS05365	COG1335	isochorismatase
GO593_RS05370	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO593_RS05380	COG0668	transmembrane transport
GO593_RS05385	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GO593_RS05390	COG1519	Transferase
GO593_RS05395	COG1902	pentaerythritol trinitrate reductase activity
GO593_RS05415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GO593_RS05440	COG0426	domain, Protein
GO593_RS05440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS05445	COG4774	siderophore transport
GO593_RS05450	COG2119	membrane
GO593_RS05460	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO593_RS05470	COG4942	peptidase
GO593_RS05485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GO593_RS05495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GO593_RS05515	COG0189	ligase activity
GO593_RS05535	COG0708	Exodeoxyribonuclease III
GO593_RS05540	COG1393	Belongs to the ArsC family
GO593_RS05555	COG3706	GGDEF domain
GO593_RS05590	COG2351	hydroxyisourate hydrolase activity
GO593_RS05595	COG2233	PERMEase
GO593_RS05605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO593_RS05615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GO593_RS05620	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS05630	COG3150	esterase
GO593_RS05645	COG3179	chitinase
GO593_RS05660	COG2918	glutathione biosynthetic process
GO593_RS05675	COG2733	membrane
GO593_RS05680	COG0436	Aminotransferase
GO593_RS05685	COG0534	Mate efflux family protein
GO593_RS05735	COG0753	catalase activity
GO593_RS05780	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GO593_RS05785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GO593_RS05795	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GO593_RS05800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO593_RS05805	COG0546	phosphoglycolate phosphatase activity
GO593_RS05815	COG0010	Belongs to the arginase family
GO593_RS05845	COG2188	Transcriptional regulator
GO593_RS05855	COG0523	cobalamin synthesis protein
GO593_RS05865	COG1113	amino acid transport
GO593_RS05875	COG0625	glutathione transferase activity
GO593_RS05895	COG1683	Conserved Protein
GO593_RS05905	COG0385	Bile acid
GO593_RS05910	COG1335	isochorismatase
GO593_RS05915	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO593_RS05935	COG2116	formate transmembrane transporter activity
GO593_RS05940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GO593_RS05945	COG2133	pyrroloquinoline quinone binding
GO593_RS05950	COG2983	Belongs to the UPF0260 family
GO593_RS05970	COG1194	a g-specific adenine glycosylase
GO593_RS05985	COG2818	Glycosylase
GO593_RS05990	COG1064	alcohol dehydrogenase
GO593_RS05995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO593_RS06010	COG0583	DNA-binding transcription factor activity
GO593_RS06015	COG0656	L-ascorbic acid biosynthetic process
GO593_RS06020	COG2814	Major facilitator Superfamily
GO593_RS06055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS06070	COG2233	PERMEase
GO593_RS06075	COG0583	DNA-binding transcription factor activity
GO593_RS06110	COG0733	neurotransmitter:sodium symporter activity
GO593_RS06120	COG0625	glutathione transferase activity
GO593_RS06155	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GO593_RS06160	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GO593_RS06165	COG0596	Alpha beta hydrolase
GO593_RS06190	COG0488	(ABC) transporter
GO593_RS06195	COG0586	Pfam SNARE associated Golgi protein
GO593_RS06205	COG0187	DNA topoisomerase II activity
GO593_RS06215	COG0592	DNA-directed DNA polymerase activity
GO593_RS06240	COG0706	membrane insertase activity
GO593_RS06255	COG1230	cation diffusion facilitator family transporter
GO593_RS06260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO593_RS06275	COG0402	S-adenosylhomocysteine deaminase activity
GO593_RS06285	COG0754	glutathionylspermidine amidase activity
GO593_RS06295	COG0861	Integral membrane protein TerC family
GO593_RS06300	COG0671	phosphoesterase, PA-phosphatase related
GO593_RS06310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GO593_RS06325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GO593_RS06330	COG2951	lytic endotransglycosylase activity
GO593_RS06380	COG0657	acetylesterase activity
GO593_RS06385	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GO593_RS06425	COG1047	Peptidyl-prolyl cis-trans
GO593_RS06435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GO593_RS06440	COG0196	riboflavin kinase activity
GO593_RS06450	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GO593_RS06455	COG1309	transcriptional regulator
GO593_RS06460	COG1116	anion transmembrane transporter activity
GO593_RS06465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO593_RS06470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO593_RS06475	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO593_RS06480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO593_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS06505	COG0546	phosphoglycolate phosphatase activity
GO593_RS06600	COG4691	Plasmid stability protein
GO593_RS06635	COG0798	PFAM Bile acid sodium symporter
GO593_RS06675	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO593_RS06700	COG2184	nucleotidyltransferase activity
GO593_RS06810	COG3023	N-Acetylmuramoyl-L-alanine amidase
GO593_RS06815	COG0728	peptidoglycan biosynthetic process
GO593_RS06840	COG1596	polysaccharide export
GO593_RS06845	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GO593_RS06875	COG0438	transferase activity, transferring glycosyl groups
GO593_RS06900	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GO593_RS06905	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GO593_RS06920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO593_RS06925	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO593_RS06945	COG0277	FAD linked oxidase domain protein
GO593_RS06950	COG1448	Aminotransferase
GO593_RS06955	COG1802	Transcriptional regulator
GO593_RS06970	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GO593_RS07055	COG0564	pseudouridine synthase activity
GO593_RS07095	COG0251	oxidation-reduction process
GO593_RS07100	COG1113	amino acid transport
GO593_RS07105	COG1113	amino acid transport
GO593_RS07125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO593_RS07130	COG1960	acyl-CoA dehydrogenase activity
GO593_RS07135	COG1024	Enoyl-CoA hydratase
GO593_RS07140	COG1024	Enoyl-CoA hydratase
GO593_RS07145	COG0477	Major facilitator Superfamily
GO593_RS07150	COG3916	Acyl-homoserine-lactone synthase
GO593_RS07160	COG2197	response regulator
GO593_RS07170	COG1960	acyl-CoA dehydrogenase activity
GO593_RS07175	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GO593_RS07175	COG3321	synthase
GO593_RS07175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GO593_RS07175	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GO593_RS07195	COG2267	carboxylic ester hydrolase activity
GO593_RS07215	COG0271	Belongs to the BolA IbaG family
GO593_RS07225	COG1192	Involved in chromosome partitioning
GO593_RS07240	COG0586	Pfam SNARE associated Golgi protein
GO593_RS07245	COG2259	Doxx family
GO593_RS07250	COG4399	Belongs to the UPF0754 family
GO593_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
GO593_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO593_RS07300	COG0281	malic enzyme
GO593_RS07305	COG2837	iron assimilation
GO593_RS07310	COG1280	lysine exporter protein (LysE YggA)
GO593_RS07315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GO593_RS07320	COG1121	(ABC) transporter
GO593_RS07385	COG0386	Belongs to the glutathione peroxidase family
GO593_RS07400	COG1309	transcriptional regulator
GO593_RS07405	COG0697	spore germination
GO593_RS07415	COG0758	DNA mediated transformation
GO593_RS07450	COG1309	transcriptional regulator
GO593_RS07485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GO593_RS07495	COG0655	NAD(P)H dehydrogenase (quinone) activity
GO593_RS07530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GO593_RS07540	COG2814	Major facilitator Superfamily
GO593_RS07550	COG1253	flavin adenine dinucleotide binding
GO593_RS07560	COG2860	membrane
GO593_RS07565	COG0477	Major facilitator Superfamily
GO593_RS07575	COG0318	PFAM AMP-dependent synthetase and ligase
GO593_RS07590	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GO593_RS07605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO593_RS07615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO593_RS07620	COG0606	chelatase, subunit chli
GO593_RS07630	COG0347	Belongs to the P(II) protein family
GO593_RS07635	COG0004	ammonium transporteR
GO593_RS07645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO593_RS07645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GO593_RS07685	COG0795	lipopolysaccharide-transporting ATPase activity
GO593_RS07690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GO593_RS07695	COG0793	Belongs to the peptidase S41A family
GO593_RS07710	COG2197	response regulator
GO593_RS07720	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GO593_RS07730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GO593_RS07735	COG4974	Belongs to the 'phage' integrase family
GO593_RS07760	COG0772	Belongs to the SEDS family
GO593_RS07765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO593_RS07770	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GO593_RS07775	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GO593_RS07800	COG0697	spore germination
GO593_RS07805	COG1538	Outer membrane efflux protein
GO593_RS07825	COG3275	phosphorelay sensor kinase activity
GO593_RS07835	COG0181	hydroxymethylbilane synthase activity
GO593_RS07880	COG1716	ATPase activity
GO593_RS07885	COG0546	phosphoglycolate phosphatase activity
GO593_RS07985	COG2056	Na+-H+ antiporter family
GO593_RS08000	COG0326	Molecular chaperone. Has ATPase activity
GO593_RS08015	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GO593_RS08075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GO593_RS08080	COG2169	Transcriptional regulator
GO593_RS08080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO593_RS08110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GO593_RS08120	COG0497	DNA recombination
GO593_RS08135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GO593_RS08145	COG0237	dephospho-CoA kinase activity
GO593_RS08190	COG0195	Participates in both transcription termination and antitermination
GO593_RS08205	COG1320	monovalent cation:proton antiporter activity
GO593_RS08210	COG2212	antiporter activity
GO593_RS08215	COG1863	multisubunit Na H antiporter MnhE subunit
GO593_RS08220	COG0651	ATP synthesis coupled electron transport
GO593_RS08225	COG1006	Multisubunit Na H antiporter MnhC subunit
GO593_RS08230	COG2111	Na H antiporter
GO593_RS08230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GO593_RS08245	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GO593_RS08250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO593_RS08265	COG2226	methyltransferase
GO593_RS08285	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GO593_RS08290	COG1074	ATP-dependent DNA helicase activity
GO593_RS08295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO593_RS08300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GO593_RS08315	COG0598	Magnesium transport protein CorA
GO593_RS08320	COG0789	Transcriptional regulator
GO593_RS08325	COG0484	heat shock protein binding
GO593_RS08340	COG0475	glutathione-regulated potassium exporter activity
GO593_RS08340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO593_RS08345	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GO593_RS08365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO593_RS08375	COG4535	Mg2 and Co2 transporter CorC
GO593_RS08380	COG0425	Belongs to the sulfur carrier protein TusA family
GO593_RS08385	COG0644	oxidoreductase
GO593_RS08385	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GO593_RS08395	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GO593_RS08410	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO593_RS08415	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GO593_RS08425	COG0493	'glutamate synthase
GO593_RS08425	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO593_RS08450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GO593_RS08465	COG0534	Mate efflux family protein
GO593_RS08475	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GO593_RS08480	COG4221	oxidoreductase activity
GO593_RS08485	COG0583	DNA-binding transcription factor activity
GO593_RS08500	COG0318	PFAM AMP-dependent synthetase and ligase
GO593_RS08505	COG1530	ribonuclease E activity
GO593_RS08515	COG0546	phosphoglycolate phosphatase activity
GO593_RS08520	COG2378	regulation of single-species biofilm formation
GO593_RS08525	COG0625	glutathione transferase activity
GO593_RS08535	COG0583	DNA-binding transcription factor activity
GO593_RS08600	COG0473	3-isopropylmalate dehydrogenase activity
GO593_RS08655	COG1301	dicarboxylic acid transport
GO593_RS08665	COG1560	Kdo2-lipid A biosynthetic process
GO593_RS08670	COG1280	lysine exporter protein (LysE YggA)
GO593_RS08675	COG0488	(ABC) transporter
GO593_RS08680	COG2900	Belongs to the SlyX family
GO593_RS08690	COG1733	regulation of RNA biosynthetic process
GO593_RS08715	COG0210	DNA helicase
GO593_RS08720	COG0724	RNA recognition motif
GO593_RS08740	COG4651	solute:proton antiporter activity
GO593_RS08740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GO593_RS08765	COG0788	formyltetrahydrofolate deformylase activity
GO593_RS08910	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GO593_RS08910	COG2813	Specifically methylates the guanine in position
GO593_RS08920	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO593_RS08930	COG4774	siderophore transport
GO593_RS08940	COG0740	serine-type endopeptidase activity
GO593_RS08960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GO593_RS08960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GO593_RS08965	COG0280	phosphate acetyltransferase
GO593_RS08965	COG0857	belongs to the CobB CobQ family
GO593_RS08970	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GO593_RS08980	COG0800	Aldolase
GO593_RS08990	COG3265	gluconokinase activity
GO593_RS08995	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS09005	COG2267	carboxylic ester hydrolase activity
GO593_RS09020	COG0793	Belongs to the peptidase S41A family
GO593_RS09055	COG1426	Protein conserved in bacteria
GO593_RS09095	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GO593_RS09105	COG1162	GTPase activity
GO593_RS09110	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GO593_RS09125	COG1538	Outer membrane efflux protein
GO593_RS09130	COG1136	(ABC) transporter
GO593_RS09130	COG0577	efflux transmembrane transporter activity
GO593_RS09135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS09160	COG0028	Belongs to the TPP enzyme family
GO593_RS09165	COG0440	acetolactate synthase activity
GO593_RS09195	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GO593_RS09210	COG0084	hydrolase, TatD family'
GO593_RS09225	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GO593_RS09235	COG0583	DNA-binding transcription factor activity
GO593_RS09245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO593_RS09250	COG2814	Major facilitator Superfamily
GO593_RS09260	COG0697	spore germination
GO593_RS09290	COG3622	Belongs to the hyi family
GO593_RS09295	COG2084	Dehydrogenase
GO593_RS09300	COG1024	Enoyl-CoA hydratase
GO593_RS09305	COG2205	protein histidine kinase activity
GO593_RS09305	COG5002	protein histidine kinase activity
GO593_RS09305	COG0784	Response regulator, receiver
GO593_RS09325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GO593_RS09335	COG3956	TIGRFAM MazG family protein
GO593_RS09340	COG1555	photosystem II stabilization
GO593_RS09345	COG0617	tRNA 3'-terminal CCA addition
GO593_RS09350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GO593_RS09370	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO593_RS09375	COG3028	Belongs to the UPF0307 family
GO593_RS09380	COG0318	PFAM AMP-dependent synthetase and ligase
GO593_RS09395	COG0625	glutathione transferase activity
GO593_RS09400	COG1238	metal cluster binding
GO593_RS09440	COG0072	phenylalanine-tRNA ligase activity
GO593_RS09470	COG0248	Ppx GppA phosphatase
GO593_RS09480	COG0037	tRNA processing
GO593_RS09495	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO593_RS09495	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GO593_RS09520	COG1764	response to oxidative stress
GO593_RS09525	COG1846	Transcriptional regulator
GO593_RS09535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO593_RS09595	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GO593_RS09600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GO593_RS09605	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GO593_RS09665	COG1214	PFAM Peptidase M22, glycoprotease
GO593_RS09680	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GO593_RS09690	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GO593_RS09695	COG0561	phosphatase activity
GO593_RS09705	COG2132	Multicopper oxidase
GO593_RS09725	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GO593_RS09730	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GO593_RS09735	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GO593_RS09765	COG1063	alcohol dehydrogenase
GO593_RS09770	COG0583	DNA-binding transcription factor activity
GO593_RS09775	COG1960	acyl-CoA dehydrogenase activity
GO593_RS09780	COG2814	Major facilitator Superfamily
GO593_RS09785	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GO593_RS09790	COG1309	transcriptional regulator
GO593_RS09805	COG1053	succinate dehydrogenase
GO593_RS09810	COG0583	DNA-binding transcription factor activity
GO593_RS09825	COG0583	DNA-binding transcription factor activity
GO593_RS09835	COG0583	DNA-binding transcription factor activity
GO593_RS09850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS09905	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GO593_RS09925	COG0745	RESPONSE REGULATOR receiver
GO593_RS09965	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GO593_RS09995	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GO593_RS10000	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GO593_RS10020	COG0583	DNA-binding transcription factor activity
GO593_RS10040	COG0668	transmembrane transport
GO593_RS10050	COG2081	HI0933 family
GO593_RS10055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GO593_RS10085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO593_RS10085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GO593_RS10095	COG0489	protein tyrosine kinase activity
GO593_RS10100	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GO593_RS10145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GO593_RS10155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GO593_RS10170	COG0730	response to heat
GO593_RS10180	COG1196	nuclear chromosome segregation
GO593_RS10200	COG2223	nitrite transmembrane transporter activity
GO593_RS10205	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GO593_RS10210	COG1877	trehalose-phosphatase activity
GO593_RS10215	COG2226	methyltransferase
GO593_RS10215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GO593_RS10215	COG0596	Alpha beta hydrolase
GO593_RS10230	COG4106	trans-aconitate 2-methyltransferase activity
GO593_RS10245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GO593_RS10250	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GO593_RS10255	COG0009	L-threonylcarbamoyladenylate synthase
GO593_RS10260	COG3101	peptidyl-lysine hydroxylation
GO593_RS10265	COG1399	metal-binding, possibly nucleic acid-binding protein
GO593_RS10290	COG1652	LysM domain
GO593_RS10295	COG0351	phosphomethylpyrimidine kinase
GO593_RS10295	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GO593_RS10295	COG0352	thiamine-phosphate diphosphorylase activity
GO593_RS10305	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GO593_RS10335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GO593_RS10365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GO593_RS10380	COG0358	DNA primase activity
GO593_RS10390	COG0564	pseudouridine synthase activity
GO593_RS10415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GO593_RS10435	COG0583	DNA-binding transcription factor activity
GO593_RS10440	COG0473	3-isopropylmalate dehydrogenase activity
GO593_RS10450	COG0657	acetylesterase activity
GO593_RS10460	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS10480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GO593_RS10480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GO593_RS10495	COG1981	membrane
GO593_RS10540	COG0456	acetyltransferase
GO593_RS10550	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GO593_RS10555	COG0492	ferredoxin-NADP+ reductase activity
GO593_RS10560	COG1674	ftsk spoiiie
GO593_RS10565	COG1280	lysine exporter protein (LysE YggA)
GO593_RS10580	COG2894	cell division
GO593_RS10595	COG0204	Acyl-transferase
GO593_RS10600	COG2885	chlorophyll binding
GO593_RS10605	COG0210	DNA helicase
GO593_RS10615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GO593_RS10630	COG0121	glutamine amidotransferase
GO593_RS10650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GO593_RS10655	COG0735	belongs to the Fur family
GO593_RS10680	COG0420	3'-5' exonuclease activity
GO593_RS10700	COG1090	epimerase
GO593_RS10715	COG2050	protein possibly involved in aromatic compounds catabolism
GO593_RS10725	COG2814	Major facilitator Superfamily
GO593_RS10730	COG0405	Gamma-glutamyltransferase
GO593_RS10740	COG0582	viral genome integration into host DNA
GO593_RS10785	COG0629	single-stranded DNA binding
GO593_RS10915	COG0477	Major facilitator Superfamily
GO593_RS10920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO593_RS10965	COG0531	amino acid
GO593_RS10970	COG2040	homocysteine
GO593_RS10995	COG1309	transcriptional regulator
GO593_RS11000	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO593_RS11005	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GO593_RS11015	COG1607	acyl-coa hydrolase
GO593_RS11025	COG0523	cobalamin synthesis protein
GO593_RS11035	COG4681	YaeQ
GO593_RS11045	COG0726	polysaccharide deacetylase
GO593_RS11045	COG1649	PFAM Uncharacterised BCR, COG1649
GO593_RS11050	COG1215	transferase activity, transferring glycosyl groups
GO593_RS11060	COG1024	Enoyl-CoA hydratase
GO593_RS11075	COG1414	Transcriptional regulator
GO593_RS11095	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS11110	COG2271	Major facilitator Superfamily
GO593_RS11120	COG2267	carboxylic ester hydrolase activity
GO593_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS11140	COG0028	Belongs to the TPP enzyme family
GO593_RS11150	COG0477	Major facilitator Superfamily
GO593_RS11155	COG0242	peptide deformylase activity
GO593_RS11160	COG2066	Belongs to the glutaminase family
GO593_RS11165	COG2207	Transcriptional regulator
GO593_RS11170	COG2223	nitrite transmembrane transporter activity
GO593_RS11185	COG0583	DNA-binding transcription factor activity
GO593_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS11195	COG2271	Major facilitator Superfamily
GO593_RS11200	COG3959	Transketolase, thiamine diphosphate binding domain
GO593_RS11205	COG3958	Transketolase
GO593_RS11215	COG0306	phosphate transporter
GO593_RS11235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GO593_RS11280	COG4181	ATPase activity
GO593_RS11285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GO593_RS11315	COG0583	DNA-binding transcription factor activity
GO593_RS11325	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO593_RS11330	COG1773	rubredoxin
GO593_RS11380	COG2851	Citrate transporter
GO593_RS11385	COG1253	flavin adenine dinucleotide binding
GO593_RS11425	COG0804	urea catabolic process
GO593_RS11435	COG0830	nickel cation binding
GO593_RS11450	COG0742	ribosomal rna small subunit methyltransferase
GO593_RS11455	COG0768	penicillin binding
GO593_RS11480	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GO593_RS11485	COG2878	Part of a membrane complex involved in electron transport
GO593_RS11490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GO593_RS11500	COG3384	dioxygenase
GO593_RS11525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GO593_RS11845	COG0739	heme binding
GO593_RS11890	COG2194	sulfuric ester hydrolase activity
GO593_RS11925	COG0006	proline dipeptidase activity
GO593_RS11930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO593_RS11935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO593_RS11955	COG1279	arginine transmembrane transporter activity
GO593_RS11960	COG0583	DNA-binding transcription factor activity
GO593_RS12000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO593_RS12005	COG1388	LysM domain
GO593_RS12005	COG0741	lytic transglycosylase activity
GO593_RS12005	COG1388	LysM domain
GO593_RS12005	COG0741	lytic transglycosylase activity
GO593_RS12015	COG4174	ABC transporter (Permease)
GO593_RS12020	COG4239	(ABC) transporter, permease
GO593_RS12025	COG4172	Belongs to the ABC transporter superfamily
GO593_RS12045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GO593_RS12055	COG4251	negative regulation of phosphorylation
GO593_RS12055	COG5001	Diguanylate cyclase
GO593_RS12055	COG2203	Gaf domain
GO593_RS12055	COG3706	GGDEF domain
GO593_RS12065	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO593_RS12065	COG1902	pentaerythritol trinitrate reductase activity
GO593_RS12075	COG0582	viral genome integration into host DNA
GO593_RS12150	COG0789	Transcriptional regulator
GO593_RS12210	COG2184	nucleotidyltransferase activity
GO593_RS12220	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GO593_RS12245	COG1309	transcriptional regulator
GO593_RS12260	COG4269	membrane
GO593_RS12300	COG1113	amino acid transport
GO593_RS12310	COG0531	amino acid
GO593_RS12330	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS12350	COG1113	amino acid transport
GO593_RS12385	COG0697	spore germination
GO593_RS12390	COG2721	sulfolactate sulfo-lyase activity
GO593_RS12395	COG2271	Major facilitator Superfamily
GO593_RS12400	COG4948	Mandelate Racemase Muconate Lactonizing
GO593_RS12410	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS12415	COG2186	Transcriptional regulator
GO593_RS12440	COG1960	acyl-CoA dehydrogenase activity
GO593_RS12450	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS12455	COG1024	Enoyl-CoA hydratase
GO593_RS12460	COG2814	Major facilitator Superfamily
GO593_RS12475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO593_RS12520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GO593_RS12525	COG2072	flavoprotein involved in K transport
GO593_RS12530	COG0300	oxidoreductase activity
GO593_RS12540	COG1309	transcriptional regulator
GO593_RS12545	COG1741	Belongs to the pirin family
GO593_RS12560	COG2072	flavoprotein involved in K transport
GO593_RS12570	COG2252	PERMEase
GO593_RS12575	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GO593_RS12580	COG3038	cytochrome b561
GO593_RS12590	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GO593_RS12600	COG0527	aspartate kinase activity
GO593_RS12655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO593_RS12660	COG4197	protein conserved in bacteria, prophage-related
GO593_RS12740	COG5410	chromosome segregation
GO593_RS12745	COG3567	Phage-associated protein, HI1409 family
GO593_RS12765	COG3566	protein conserved in bacteria
GO593_RS12890	COG0582	viral genome integration into host DNA
GO593_RS12900	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO593_RS12910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GO593_RS12925	COG0667	Aldo Keto reductase
GO593_RS12935	COG1765	OsmC-like protein
GO593_RS12950	COG0542	response to heat
GO593_RS12985	COG2885	chlorophyll binding
GO593_RS12995	COG0625	glutathione transferase activity
GO593_RS13015	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GO593_RS13035	COG3634	alkyl hydroperoxide reductase activity
GO593_RS13045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GO593_RS13055	COG0450	alkyl hydroperoxide reductase
GO593_RS13060	COG1643	Atp-dependent helicase
GO593_RS13075	COG2814	Major facilitator Superfamily
GO593_RS13080	COG3135	benzoate transporter
GO593_RS13085	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS13090	COG0543	2 iron, 2 sulfur cluster binding
GO593_RS13090	COG0633	Ferredoxin
GO593_RS13095	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GO593_RS13100	COG4638	Rieske (2fe-2S)
GO593_RS13105	COG0583	DNA-binding transcription factor activity
GO593_RS13155	COG1570	exodeoxyribonuclease VII activity
GO593_RS13190	COG1280	lysine exporter protein (LysE YggA)
GO593_RS13195	COG1278	Cold shock
GO593_RS13230	COG2814	Major facilitator Superfamily
GO593_RS13315	COG0210	DNA helicase
GO593_RS13325	COG5377	YqaJ viral recombinase family
GO593_RS13530	COG0517	IMP dehydrogenase activity
GO593_RS13530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GO593_RS13535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GO593_RS13545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GO593_RS13550	COG1137	ATPase activity
GO593_RS13625	COG4122	O-methyltransferase activity
GO593_RS13635	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GO593_RS13650	COG1522	sequence-specific DNA binding
GO593_RS13665	COG1560	Kdo2-lipid A biosynthetic process
GO593_RS13675	COG2814	Major facilitator Superfamily
GO593_RS13695	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO593_RS13730	COG0583	DNA-binding transcription factor activity
GO593_RS13735	COG1914	H( )-stimulated, divalent metal cation uptake system
GO593_RS13755	COG4770	biotin carboxylase activity
GO593_RS13760	COG0038	chloride channel
GO593_RS13765	COG2831	hemolysin activation secretion protein
GO593_RS13770	COG3210	domain, Protein
GO593_RS13785	COG1309	transcriptional regulator
GO593_RS13795	COG1063	alcohol dehydrogenase
GO593_RS13810	COG0439	Biotin carboxylase
GO593_RS13815	COG2249	NAD(P)H dehydrogenase (quinone) activity
GO593_RS13820	COG1733	regulation of RNA biosynthetic process
GO593_RS13835	COG0864	Transcriptional regulator
GO593_RS13845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO593_RS13850	COG1116	anion transmembrane transporter activity
GO593_RS13965	COG0590	tRNA wobble adenosine to inosine editing
GO593_RS13970	COG2807	transmembrane transport
GO593_RS13985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GO593_RS14005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GO593_RS14050	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS14055	COG0531	amino acid
GO593_RS14060	COG1760	l-serine dehydratase
GO593_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS14065	COG2030	dehydratase
GO593_RS14070	COG3396	Phenylacetate-CoA oxygenase
GO593_RS14075	COG3460	Phenylacetate-CoA oxygenase
GO593_RS14080	COG3396	Phenylacetate-CoA oxygenase
GO593_RS14085	COG2151	metal-sulfur cluster biosynthetic enzyme
GO593_RS14090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO593_RS14095	COG1024	Enoyl-CoA hydratase
GO593_RS14100	COG1024	Enoyl-CoA hydratase
GO593_RS14105	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO593_RS14110	COG0183	Belongs to the thiolase family
GO593_RS14115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GO593_RS14120	COG3327	negative regulation of DNA-templated transcription, initiation
GO593_RS14130	COG2050	protein possibly involved in aromatic compounds catabolism
GO593_RS14170	COG2207	Transcriptional regulator
GO593_RS14185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GO593_RS14190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GO593_RS14195	COG2271	Major facilitator Superfamily
GO593_RS14200	COG0753	catalase activity
GO593_RS14205	COG3038	cytochrome b561
GO593_RS14225	COG2267	carboxylic ester hydrolase activity
GO593_RS14230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS14235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO593_RS14240	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS14250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GO593_RS14260	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS14265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO593_RS14270	COG0583	DNA-binding transcription factor activity
GO593_RS14280	COG1414	Transcriptional regulator
GO593_RS14285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GO593_RS14295	COG1840	ABC-type Fe3 transport system, periplasmic component
GO593_RS14300	COG3842	ATPase activity
GO593_RS14315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GO593_RS14320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GO593_RS14325	COG2814	Major facilitator Superfamily
GO593_RS14330	COG1960	acyl-CoA dehydrogenase activity
GO593_RS14345	COG1024	Enoyl-CoA hydratase
GO593_RS14355	COG2814	Major facilitator Superfamily
GO593_RS14365	COG0183	Belongs to the thiolase family
GO593_RS14370	COG1250	3-hydroxyacyl-CoA dehydrogenase
GO593_RS14375	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS14380	COG1024	Enoyl-CoA hydratase
GO593_RS14385	COG1960	acyl-CoA dehydrogenase activity
GO593_RS14390	COG2814	Major facilitator Superfamily
GO593_RS14395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GO593_RS14400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GO593_RS14410	COG2814	Major facilitator Superfamily
GO593_RS14420	COG1960	acyl-CoA dehydrogenase activity
GO593_RS14435	COG0583	DNA-binding transcription factor activity
GO593_RS14445	COG4770	biotin carboxylase activity
GO593_RS14450	COG1024	Enoyl-CoA hydratase
GO593_RS14455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GO593_RS14460	COG1960	acyl-CoA dehydrogenase activity
GO593_RS14465	COG1309	transcriptional regulator
GO593_RS14470	COG0318	PFAM AMP-dependent synthetase and ligase
GO593_RS14490	COG0583	DNA-binding transcription factor activity
GO593_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS14555	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GO593_RS14575	COG2205	protein histidine kinase activity
GO593_RS14575	COG0784	Response regulator, receiver
GO593_RS14595	COG0765	amino acid transport
GO593_RS14600	COG0765	amino acid transport
GO593_RS14605	COG1126	abc transporter atp-binding protein
GO593_RS14610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO593_RS14615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GO593_RS14630	COG1280	lysine exporter protein (LysE YggA)
GO593_RS14635	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GO593_RS14640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO593_RS14645	COG1045	serine acetyltransferase
GO593_RS14660	COG0583	DNA-binding transcription factor activity
GO593_RS14665	COG0625	glutathione transferase activity
GO593_RS14670	COG0625	glutathione transferase activity
GO593_RS14675	COG0583	DNA-binding transcription factor activity
GO593_RS14685	COG1346	cytolysis
GO593_RS14705	COG2814	Major facilitator Superfamily
GO593_RS14715	COG0583	DNA-binding transcription factor activity
GO593_RS14725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GO593_RS14730	COG3052	prosthetic group binding
GO593_RS14770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO593_RS14780	COG1294	oxidase, subunit
GO593_RS14785	COG1271	oxidase subunit
GO593_RS14805	COG0477	Major facilitator Superfamily
GO593_RS14815	COG4521	taurine ABC transporter
GO593_RS14820	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GO593_RS14825	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO593_RS14830	COG2175	clavaminate synthase activity
GO593_RS14840	COG1953	Uracil, thiamine, allantoin
GO593_RS14850	COG0583	DNA-binding transcription factor activity
GO593_RS14860	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GO593_RS14875	COG0640	Transcriptional regulator
GO593_RS14880	COG0798	PFAM Bile acid sodium symporter
GO593_RS14885	COG0583	DNA-binding transcription factor activity
GO593_RS14900	COG3634	alkyl hydroperoxide reductase activity
GO593_RS14940	COG0436	Aminotransferase
GO593_RS14950	COG0386	Belongs to the glutathione peroxidase family
GO593_RS14990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GO593_RS15015	COG0012	GTP binding
GO593_RS15020	COG2011	ABC-type metal ion transport system permease component
GO593_RS15025	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO593_RS15035	COG1464	Belongs to the NlpA lipoprotein family
GO593_RS15065	COG0765	amino acid transport
GO593_RS15070	COG0765	amino acid transport
GO593_RS15075	COG1126	abc transporter atp-binding protein
GO593_RS15085	COG1522	sequence-specific DNA binding
GO593_RS15100	COG1309	transcriptional regulator
GO593_RS15110	COG1484	DNA-dependent DNA replication
GO593_RS15115	COG4584	PFAM Integrase catalytic
GO593_RS15130	COG1002	Type II restriction enzyme, methylase subunits
GO593_RS15135	COG1061	Type III restriction enzyme res subunit
GO593_RS15145	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GO593_RS15175	COG0583	DNA-binding transcription factor activity
GO593_RS15185	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GO593_RS15195	COG0697	spore germination
GO593_RS15220	COG3121	Chaperone
GO593_RS15225	COG3539	Fimbrial protein
GO593_RS15250	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GO593_RS15250	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GO593_RS15295	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GO593_RS15305	COG2353	YceI-like domain
GO593_RS15315	COG3698	Phosphodiester glycosidase
GO593_RS15330	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GO593_RS15335	COG0506	proline dehydrogenase activity
GO593_RS15335	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GO593_RS15335	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GO593_RS15345	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GO593_RS15350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GO593_RS15370	COG1132	(ABC) transporter
GO593_RS15375	COG3122	Protein conserved in bacteria
GO593_RS15380	COG3619	membrane
GO593_RS15390	COG0640	Transcriptional regulator
GO593_RS15400	COG2850	peptidyl-arginine hydroxylation
GO593_RS15405	COG0424	maF-like protein
GO593_RS15425	COG0191	fructose-bisphosphate aldolase activity
GO593_RS15430	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO593_RS15445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GO593_RS15455	COG1192	Involved in chromosome partitioning
GO593_RS15460	COG1475	DNA binding
GO593_RS15465	COG0811	peptide transport
GO593_RS15475	COG1132	(ABC) transporter
GO593_RS15480	COG1663	tetraacyldisaccharide 4'-kinase activity
GO593_RS15500	COG0084	hydrolase, TatD family'
GO593_RS15565	COG0776	regulation of translation
GO593_RS15595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GO593_RS15600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GO593_RS15630	COG4206	TonB-dependent receptor
GO593_RS15650	COG0339	signal peptide processing
GO593_RS15660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GO593_RS15695	COG0702	epimerase
GO593_RS15700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO593_RS15720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GO593_RS15750	COG0316	Belongs to the HesB IscA family
GO593_RS15755	COG0822	iron-sulfur transferase activity
GO593_RS15780	COG0776	regulation of translation
GO593_RS15785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GO593_RS15790	COG2207	Transcriptional regulator
GO593_RS15795	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO593_RS15800	COG1960	acyl-CoA dehydrogenase activity
GO593_RS15805	COG1960	acyl-CoA dehydrogenase activity
GO593_RS15820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GO593_RS15840	COG4264	IucA IucC family
GO593_RS15845	COG4264	IucA IucC family
GO593_RS15855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GO593_RS15905	COG0406	alpha-ribazole phosphatase activity
GO593_RS15920	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GO593_RS15925	COG0730	response to heat
GO593_RS15945	COG4773	Receptor
GO593_RS15950	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO593_RS15965	COG1131	(ABC) transporter
GO593_RS15970	COG0842	Transport permease protein
GO593_RS15975	COG0842	Transport permease protein
GO593_RS16030	COG2226	methyltransferase
GO593_RS16055	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GO593_RS16075	COG3706	GGDEF domain
GO593_RS16090	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GO593_RS16095	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO593_RS16100	COG0022	dehydrogenase e1 component
GO593_RS16105	COG0508	dehydrogenase complex catalyzes the overall conversion of
GO593_RS16110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GO593_RS16120	COG1063	alcohol dehydrogenase
GO593_RS16125	COG3781	membrane
GO593_RS16135	COG3453	Protein conserved in bacteria
GO593_RS16135	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO593_RS16145	COG0730	response to heat
GO593_RS16160	COG2207	Transcriptional regulator
GO593_RS16160	COG3708	Transcriptional regulator
GO593_RS16165	COG1733	regulation of RNA biosynthetic process
GO593_RS16170	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GO593_RS16180	COG2188	Transcriptional regulator
GO593_RS16195	COG4521	taurine ABC transporter
GO593_RS16200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GO593_RS16220	COG0477	Major facilitator Superfamily
GO593_RS16230	COG1027	Aspartate ammonia-lyase
GO593_RS16245	COG0583	DNA-binding transcription factor activity
GO593_RS16250	COG0583	DNA-binding transcription factor activity
GO593_RS16255	COG0183	Belongs to the thiolase family
GO593_RS16260	COG2031	fatty acid transporter
GO593_RS16275	COG0583	DNA-binding transcription factor activity
GO593_RS16295	COG1309	transcriptional regulator
GO593_RS16305	COG2610	gluconate transmembrane transporter activity
GO593_RS16310	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16315	COG2207	Transcriptional regulator
GO593_RS16330	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS16355	COG0543	2 iron, 2 sulfur cluster binding
GO593_RS16355	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GO593_RS16360	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GO593_RS16365	COG4638	Rieske (2fe-2S)
GO593_RS16375	COG0725	ABC transporter, periplasmic molybdate-binding protein
GO593_RS16380	COG4149	molybdate abc transporter
GO593_RS16385	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GO593_RS16390	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16395	COG3433	isochorismatase activity
GO593_RS16395	COG1535	isochorismatase
GO593_RS16460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GO593_RS16475	COG0753	catalase activity
GO593_RS16485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GO593_RS16525	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GO593_RS16530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GO593_RS16535	COG0745	RESPONSE REGULATOR receiver
GO593_RS16540	COG2205	protein histidine kinase activity
GO593_RS16550	COG2207	Transcriptional regulator
GO593_RS16565	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
GO593_RS16625	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GO593_RS16695	COG1401	restriction endodeoxyribonuclease activity
GO593_RS16740	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GO593_RS16760	COG1120	ATPase activity
GO593_RS16765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GO593_RS16775	COG1064	alcohol dehydrogenase
GO593_RS16790	COG2207	Transcriptional regulator
GO593_RS16795	COG2084	Dehydrogenase
GO593_RS16805	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GO593_RS16810	COG0583	DNA-binding transcription factor activity
GO593_RS16820	COG0129	dihydroxy-acid dehydratase activity
GO593_RS16825	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS16840	COG1566	PFAM secretion protein HlyD family protein
GO593_RS16855	COG0583	DNA-binding transcription factor activity
GO593_RS16870	COG2188	Transcriptional regulator
GO593_RS16905	COG3210	domain, Protein
GO593_RS16910	COG2831	hemolysin activation secretion protein
GO593_RS16925	COG0318	PFAM AMP-dependent synthetase and ligase
GO593_RS16935	COG1960	acyl-CoA dehydrogenase activity
GO593_RS16945	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16955	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS16960	COG0583	DNA-binding transcription factor activity
GO593_RS16965	COG1309	transcriptional regulator
GO593_RS16990	COG0789	Transcriptional regulator
GO593_RS17005	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO593_RS17005	COG1902	pentaerythritol trinitrate reductase activity
GO593_RS17020	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS17040	COG2186	Transcriptional regulator
GO593_RS17050	COG0583	DNA-binding transcription factor activity
GO593_RS17055	COG4948	Mandelate Racemase Muconate Lactonizing
GO593_RS17060	COG4829	muconolactone delta-isomerase
GO593_RS17070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GO593_RS17075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GO593_RS17080	COG0183	Belongs to the thiolase family
GO593_RS17085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GO593_RS17095	COG1012	belongs to the aldehyde dehydrogenase family
GO593_RS17105	COG3733	amine oxidase
GO593_RS17115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS17125	COG1028	Short-chain dehydrogenase reductase Sdr
GO593_RS17135	COG4638	Rieske (2fe-2S)
GO593_RS17155	COG0154	amidase activity
GO593_RS17165	COG2814	Major facilitator Superfamily
GO593_RS17190	COG1960	acyl-CoA dehydrogenase activity
GO593_RS17195	COG0583	DNA-binding transcription factor activity
GO593_RS17200	COG1414	Transcriptional regulator
GO593_RS17215	COG2391	methyltransferase activity
GO593_RS17225	COG4993	Dehydrogenase
GO593_RS17230	COG3659	wide pore channel activity
GO593_RS17235	COG3420	alginic acid biosynthetic process
GO593_RS17240	COG0710	3-dehydroquinate dehydratase activity
GO593_RS17245	COG3485	protocatechuate 3,4-dioxygenase
GO593_RS17250	COG3485	protocatechuate 3,4-dioxygenase
GO593_RS17255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GO593_RS17260	COG2271	Major facilitator Superfamily
GO593_RS17265	COG0596	Alpha beta hydrolase
GO593_RS17270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GO593_RS17275	COG0183	Belongs to the thiolase family
GO593_RS17280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GO593_RS17285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GO593_RS17295	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GO593_RS17300	COG2323	membrane
GO593_RS17345	COG1902	pentaerythritol trinitrate reductase activity
GO593_RS17345	COG0446	pyridine nucleotide-disulphide oxidoreductase
GO593_RS17370	COG0542	response to heat
GO593_RS17375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GO593_RS17405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GO593_RS17410	COG0569	domain protein
GO593_RS17415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GO593_RS17430	COG4774	siderophore transport
GO593_RS17435	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GO593_RS17445	COG1585	Membrane protein implicated in regulation of membrane protease activity
GO593_RS17460	COG1294	oxidase, subunit
GO593_RS17465	COG4890	Cyd operon protein YbgT
GO593_RS17475	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GO593_RS17485	COG0552	protein localization to endoplasmic reticulum
GO593_RS17510	COG0516	GMP reductase activity
GO593_RS17510	COG0517	IMP dehydrogenase activity
GO593_RS17515	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GO593_RS17520	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GO593_RS17530	COG0583	DNA-binding transcription factor activity
GO593_RS17535	COG0024	Methionine aminopeptidase
GO593_RS17565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GO593_RS17565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GO593_RS17570	COG1105	Belongs to the carbohydrate kinase PfkB family
GO593_RS17575	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
GO593_RS17575	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO593_RS17575	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GO593_RS17595	COG3300	MHYT domain
GO593_RS17595	COG5001	Diguanylate cyclase
GO593_RS17610	COG2135	peptidase activity
GO593_RS17615	COG0659	secondary active sulfate transmembrane transporter activity
GO593_RS17630	COG1113	amino acid transport
GO593_RS17640	COG1522	sequence-specific DNA binding
GO593_RS17665	COG1011	Hydrolase
GO593_RS17670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GO593_RS17680	COG2137	regulation of response to DNA damage stimulus
GO593_RS17695	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO593_RS17730	COG0575	Belongs to the CDS family
GO593_RS17735	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GO593_RS17760	COG3852	Histidine kinase
GO593_RS17765	COG2204	response regulator
GO593_RS17820	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GO593_RS17825	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GO593_RS17845	COG0697	spore germination
GO593_RS17850	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GO593_RS17860	COG0303	'Molybdopterin
GO593_RS17865	COG0315	cyclic pyranopterin monophosphate synthase activity
GO593_RS17865	COG0521	Mo-molybdopterin cofactor biosynthetic process
GO593_RS17880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GO593_RS17895	COG0243	molybdopterin cofactor binding
GO593_RS17900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO593_RS17905	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GO593_RS17905	COG2146	nitrite reductase [NAD(P)H] activity
GO593_RS17915	COG0745	RESPONSE REGULATOR receiver
GO593_RS17920	COG1116	anion transmembrane transporter activity
GO593_RS17920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GO593_RS17940	COG0511	ligase activity, forming carbon-carbon bonds
GO593_RS17955	COG2814	Major facilitator Superfamily
GO593_RS17975	COG0069	glutamate synthase activity
GO593_RS17995	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GO593_RS18005	COG1454	alcohol dehydrogenase
GO593_RS18010	COG0824	Thioesterase
GO593_RS18020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GO593_RS18040	COG2030	dehydratase
GO593_RS18050	COG0183	Belongs to the thiolase family
GO593_RS18060	COG0583	DNA-binding transcription factor activity
GO593_RS18065	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GO593_RS18075	COG1522	sequence-specific DNA binding
GO593_RS18080	COG3135	benzoate transporter
GO593_RS18090	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GO593_RS18105	COG0589	response to stress
GO593_RS18110	COG0488	(ABC) transporter
GO593_RS18130	COG4773	Receptor
GO593_RS18160	COG0668	transmembrane transport
GO593_RS18170	COG1309	transcriptional regulator
GO593_RS18185	COG1605	Chorismate mutase
GO593_RS18225	COG0308	aminopeptidase N
GO593_RS18250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GO593_RS18255	COG1454	alcohol dehydrogenase
GO593_RS18275	COG0531	amino acid
GO593_RS18280	COG4303	Ethanolamine ammonia lyase large subunit
GO593_RS18285	COG4302	ethanolamine ammonia-lyase activity
GO593_RS18290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GO593_RS18290	COG0519	Catalyzes the synthesis of GMP from XMP
GO593_RS18295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GO593_RS18305	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GO593_RS18320	COG0697	spore germination
GO593_RS18325	COG1923	regulation of RNA biosynthetic process
GO593_RS18335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GO593_RS18340	COG0802	atpase or kinase
GO593_RS18360	COG1187	pseudouridine synthase activity
GO593_RS18375	COG0583	DNA-binding transcription factor activity
GO593_RS18390	COG2814	Major facilitator Superfamily
GO593_RS18395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GO593_RS18420	COG0729	surface antigen
GO593_RS18440	COG0174	glutamine synthetase
GO593_RS18445	COG0745	RESPONSE REGULATOR receiver
GO593_RS18450	COG2205	protein histidine kinase activity
GO593_RS18460	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GO593_RS18465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GO593_RS18490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GO593_RS18495	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GO593_RS18530	COG0583	DNA-binding transcription factor activity
GO593_RS18545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GO593_RS18555	COG3658	cytochrome
GO593_RS18560	COG1215	transferase activity, transferring glycosyl groups
GO593_RS18565	COG0726	polysaccharide deacetylase
GO593_RS18565	COG1649	PFAM Uncharacterised BCR, COG1649
GO593_RS18590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GO593_RS18595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GO593_RS18605	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GO593_RS18630	COG0305	Participates in initiation and elongation during chromosome replication
GO593_RS18635	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GO593_RS18645	COG1305	Transglutaminase-like
GO593_RS18655	COG2308	Evidence 4 Homologs of previously reported genes of
GO593_RS18685	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GO593_RS18690	COG0138	bifunctional purine biosynthesis protein purh
GO593_RS18695	COG0151	Belongs to the GarS family
GO593_RS18700	COG1464	Belongs to the NlpA lipoprotein family
GO593_RS18705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GO593_RS18710	COG2011	ABC-type metal ion transport system permease component
GO593_RS18715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GO593_RS18725	COG1301	dicarboxylic acid transport
GO593_RS18755	COG1794	racemase activity, acting on amino acids and derivatives
GO593_RS18775	COG0745	RESPONSE REGULATOR receiver
GO593_RS18780	COG0642	Histidine kinase
GO593_RS18785	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO593_RS18795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GO593_RS18835	COG2351	hydroxyisourate hydrolase activity
GO593_RS18845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GO593_RS18845	COG3008	intermembrane lipid transfer
GO593_RS18850	COG2995	paraquat-inducible protein a
GO593_RS18880	COG1051	belongs to the nudix hydrolase family
GO593_RS18885	COG0477	Major facilitator Superfamily
GO593_RS18940	COG2186	Transcriptional regulator
GO593_RS18980	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
GO593_RS19005	COG1764	response to oxidative stress
GO593_RS19010	COG1846	Transcriptional regulator