locus-tag	class	description
HTZ92_RS00010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HTZ92_RS00020	COG1113	amino acid transport
HTZ92_RS00030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HTZ92_RS00035	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS00045	COG1335	isochorismatase
HTZ92_RS00075	COG2814	Major facilitator Superfamily
HTZ92_RS00080	COG0583	DNA-binding transcription factor activity
HTZ92_RS00100	COG0667	Aldo Keto reductase
HTZ92_RS00130	COG1733	regulation of RNA biosynthetic process
HTZ92_RS00135	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS00205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HTZ92_RS00245	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HTZ92_RS00275	COG0427	acetyl-CoA hydrolase
HTZ92_RS00300	COG0659	secondary active sulfate transmembrane transporter activity
HTZ92_RS00305	COG4221	oxidoreductase activity
HTZ92_RS00310	COG2873	o-acetylhomoserine
HTZ92_RS00315	COG0488	(ABC) transporter
HTZ92_RS00380	COG0833	amino acid
HTZ92_RS00425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HTZ92_RS00430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HTZ92_RS00445	COG2226	methyltransferase
HTZ92_RS00495	COG0069	glutamate synthase activity
HTZ92_RS00495	COG0067	glutamate synthase
HTZ92_RS00495	COG0070	glutamate synthase
HTZ92_RS00500	COG0493	'glutamate synthase
HTZ92_RS00510	COG1704	LemA family
HTZ92_RS00515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HTZ92_RS00535	COG3307	-O-antigen
HTZ92_RS00555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HTZ92_RS00570	COG0194	GDP metabolic process
HTZ92_RS00620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HTZ92_RS00640	COG5380	lipid catabolic process
HTZ92_RS00645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HTZ92_RS00670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HTZ92_RS00675	COG0277	FAD linked oxidase domain protein
HTZ92_RS00685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HTZ92_RS00690	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS00705	COG1289	transmembrane transporter activity
HTZ92_RS00715	COG0628	permease
HTZ92_RS00720	COG1192	Involved in chromosome partitioning
HTZ92_RS00750	COG0833	amino acid
HTZ92_RS00755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HTZ92_RS00760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HTZ92_RS00770	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS00810	COG0583	DNA-binding transcription factor activity
HTZ92_RS00850	COG0517	IMP dehydrogenase activity
HTZ92_RS00855	COG1983	PspC domain protein
HTZ92_RS00865	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS00880	COG0408	coproporphyrinogen oxidase activity
HTZ92_RS00900	COG0513	Belongs to the DEAD box helicase family
HTZ92_RS00910	COG1127	ABC transporter
HTZ92_RS00915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HTZ92_RS00925	COG2854	intermembrane phospholipid transfer
HTZ92_RS00935	COG0598	Magnesium transport protein CorA
HTZ92_RS00945	COG0494	nUDIX hydrolase
HTZ92_RS00950	COG1040	competence protein
HTZ92_RS00955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HTZ92_RS00975	COG1946	Acyl-CoA thioesterase
HTZ92_RS00980	COG1301	dicarboxylic acid transport
HTZ92_RS00995	COG1959	2 iron, 2 sulfur cluster binding
HTZ92_RS01000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTZ92_RS01000	COG1017	nitric oxide dioxygenase activity
HTZ92_RS01005	COG0433	COG0433 Predicted ATPase
HTZ92_RS01010	COG0626	cystathionine gamma-synthase activity
HTZ92_RS01165	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS01170	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HTZ92_RS01200	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HTZ92_RS01205	COG0339	signal peptide processing
HTZ92_RS01210	COG0557	exoribonuclease II activity
HTZ92_RS01255	COG0179	Fumarylacetoacetate (FAA) hydrolase
HTZ92_RS01260	COG2169	Transcriptional regulator
HTZ92_RS01265	COG0697	spore germination
HTZ92_RS01270	COG1295	ribonuclease BN
HTZ92_RS01305	COG1702	phosphate starvation-inducible protein PhoH
HTZ92_RS01315	COG0739	heme binding
HTZ92_RS01315	COG0741	lytic transglycosylase activity
HTZ92_RS01315	COG1196	nuclear chromosome segregation
HTZ92_RS01345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HTZ92_RS01350	COG1183	phosphatidylcholine synthase activity
HTZ92_RS01395	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS01400	COG1309	transcriptional regulator
HTZ92_RS01415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HTZ92_RS01420	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS01440	COG2969	positive regulation of protein catabolic process
HTZ92_RS01450	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HTZ92_RS01465	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HTZ92_RS01470	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HTZ92_RS01490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HTZ92_RS01500	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HTZ92_RS01505	COG1408	metallophosphoesterase
HTZ92_RS01515	COG2199	diguanylate cyclase activity
HTZ92_RS01575	COG1607	acyl-coa hydrolase
HTZ92_RS01605	COG2350	Protein conserved in bacteria
HTZ92_RS01615	COG0613	PHP domain protein
HTZ92_RS01620	COG3781	membrane
HTZ92_RS01630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HTZ92_RS01635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HTZ92_RS01645	COG1862	Preprotein translocase
HTZ92_RS01680	COG2205	protein histidine kinase activity
HTZ92_RS01685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HTZ92_RS01705	COG0726	polysaccharide deacetylase
HTZ92_RS01710	COG0463	Glycosyl transferase, family 2
HTZ92_RS01715	COG0438	transferase activity, transferring glycosyl groups
HTZ92_RS01780	COG0625	glutathione transferase activity
HTZ92_RS01785	COG0583	DNA-binding transcription factor activity
HTZ92_RS01790	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS01795	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS01805	COG2205	protein histidine kinase activity
HTZ92_RS01810	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS01815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HTZ92_RS01835	COG2096	Adenosyltransferase
HTZ92_RS01840	COG4206	TonB-dependent receptor
HTZ92_RS01885	COG0285	dihydrofolate synthase activity
HTZ92_RS01905	COG0450	alkyl hydroperoxide reductase
HTZ92_RS01920	COG0477	Major facilitator Superfamily
HTZ92_RS01925	COG1272	protein, Hemolysin III
HTZ92_RS01955	COG0183	Belongs to the thiolase family
HTZ92_RS01960	COG2207	Transcriptional regulator
HTZ92_RS01980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTZ92_RS02000	COG0183	Belongs to the thiolase family
HTZ92_RS02010	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HTZ92_RS02010	COG2885	chlorophyll binding
HTZ92_RS02020	COG1690	Belongs to the RtcB family
HTZ92_RS02025	COG0833	amino acid
HTZ92_RS02035	COG2233	PERMEase
HTZ92_RS02040	COG1217	gtp-binding protein TYPA
HTZ92_RS02065	COG2094	Belongs to the DNA glycosylase MPG family
HTZ92_RS02070	COG4772	TonB-dependent receptor
HTZ92_RS02075	COG1902	pentaerythritol trinitrate reductase activity
HTZ92_RS02090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTZ92_RS02095	COG0354	folic acid binding
HTZ92_RS02105	COG3189	MarR family transcriptional regulator
HTZ92_RS02110	COG2824	Alkylphosphonate utilization operon protein PhnA
HTZ92_RS02115	COG3422	double-strand break repair
HTZ92_RS02155	COG0840	transmembrane signaling receptor activity
HTZ92_RS02175	COG5510	response to toxic substance
HTZ92_RS02185	COG2832	Protein of unknown function (DUF454)
HTZ92_RS02190	COG1376	ErfK ybiS ycfS ynhG family protein
HTZ92_RS02230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HTZ92_RS02240	COG1289	transmembrane transporter activity
HTZ92_RS02245	COG2814	Major facilitator Superfamily
HTZ92_RS02265	COG1115	amino acid carrier protein
HTZ92_RS02270	COG1752	Esterase of the alpha-beta hydrolase superfamily
HTZ92_RS02275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HTZ92_RS02280	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HTZ92_RS02305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HTZ92_RS02315	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HTZ92_RS02320	COG1077	Cell shape determining protein MreB Mrl
HTZ92_RS02325	COG1792	Involved in formation and maintenance of cell shape
HTZ92_RS02330	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HTZ92_RS02335	COG0424	maF-like protein
HTZ92_RS02340	COG1530	ribonuclease E activity
HTZ92_RS02350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTZ92_RS02360	COG0560	Phosphoserine phosphatase
HTZ92_RS02370	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS02395	COG2207	Transcriptional regulator
HTZ92_RS02415	COG1113	amino acid transport
HTZ92_RS02420	COG2828	Protein conserved in bacteria
HTZ92_RS02425	COG0142	geranyltranstransferase activity
HTZ92_RS02430	COG2315	Protein conserved in bacteria
HTZ92_RS02445	COG1752	Esterase of the alpha-beta hydrolase superfamily
HTZ92_RS02465	COG2194	sulfuric ester hydrolase activity
HTZ92_RS02470	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS02475	COG0642	Histidine kinase
HTZ92_RS02490	COG0004	ammonium transporteR
HTZ92_RS02495	COG0583	DNA-binding transcription factor activity
HTZ92_RS02515	COG0525	valine-tRNA ligase activity
HTZ92_RS02525	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS02535	COG0393	Putative heavy-metal-binding
HTZ92_RS02540	COG0393	Putative heavy-metal-binding
HTZ92_RS02545	COG1538	Outer membrane efflux protein
HTZ92_RS02555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS02560	COG0671	phosphoesterase, PA-phosphatase related
HTZ92_RS02590	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HTZ92_RS02605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HTZ92_RS02605	COG1648	precorrin-2 dehydrogenase activity
HTZ92_RS02610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HTZ92_RS02625	COG0531	amino acid
HTZ92_RS02640	COG0321	lipoyl(octanoyl) transferase activity
HTZ92_RS02645	COG2921	Belongs to the UPF0250 family
HTZ92_RS02680	COG2009	succinate dehydrogenase
HTZ92_RS02685	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HTZ92_RS02690	COG1053	succinate dehydrogenase
HTZ92_RS02695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HTZ92_RS02720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTZ92_RS02740	COG2354	Protein conserved in bacteria
HTZ92_RS02745	COG2321	neutral zinc metallopeptidase
HTZ92_RS02765	COG2843	Capsule synthesis protein
HTZ92_RS02780	COG0589	response to stress
HTZ92_RS02800	COG0505	Belongs to the CarA family
HTZ92_RS02825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HTZ92_RS02830	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HTZ92_RS02880	COG0477	Major facilitator Superfamily
HTZ92_RS02885	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HTZ92_RS02900	COG1597	lipid kinase activity
HTZ92_RS02905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HTZ92_RS02930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ92_RS02935	COG0584	glycerophosphoryl diester phosphodiesterase
HTZ92_RS02955	COG0741	lytic transglycosylase activity
HTZ92_RS02975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HTZ92_RS02990	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTZ92_RS03015	COG0778	Nitroreductase
HTZ92_RS03030	COG1929	Belongs to the glycerate kinase type-1 family
HTZ92_RS03035	COG0243	molybdopterin cofactor binding
HTZ92_RS03040	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HTZ92_RS03045	COG3339	Conserved Protein
HTZ92_RS03055	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HTZ92_RS03070	COG1113	amino acid transport
HTZ92_RS03080	COG0019	diaminopimelate decarboxylase activity
HTZ92_RS03095	COG2267	carboxylic ester hydrolase activity
HTZ92_RS03100	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS03105	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HTZ92_RS03135	COG0463	Glycosyl transferase, family 2
HTZ92_RS03155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS03185	COG4591	ABC-type transport system involved in lipoprotein release permease component
HTZ92_RS03190	COG1136	(ABC) transporter
HTZ92_RS03195	COG0658	competence protein
HTZ92_RS03195	COG2333	competence protein COMEC
HTZ92_RS03205	COG0616	signal peptide processing
HTZ92_RS03205	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HTZ92_RS03210	COG0596	Alpha beta hydrolase
HTZ92_RS03215	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HTZ92_RS03225	COG0628	permease
HTZ92_RS03260	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HTZ92_RS03280	COG0823	Involved in the tonB-independent uptake of proteins
HTZ92_RS03300	COG0824	Thioesterase
HTZ92_RS03305	COG1473	amidohydrolase
HTZ92_RS03325	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HTZ92_RS03325	COG0047	phosphoribosylformylglycinamidine synthase activity
HTZ92_RS03330	COG2814	Major facilitator Superfamily
HTZ92_RS03340	COG1024	Enoyl-CoA hydratase
HTZ92_RS03345	COG1051	belongs to the nudix hydrolase family
HTZ92_RS03345	COG1056	cytidyltransferase-related domain
HTZ92_RS03355	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HTZ92_RS03370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HTZ92_RS03385	COG4625	pathogenesis
HTZ92_RS03390	COG0583	DNA-binding transcription factor activity
HTZ92_RS03395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HTZ92_RS03400	COG4208	sulfate ABC transporter
HTZ92_RS03405	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HTZ92_RS03415	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HTZ92_RS03420	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HTZ92_RS03425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HTZ92_RS03445	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HTZ92_RS03460	COG0681	Belongs to the peptidase S26 family
HTZ92_RS03475	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HTZ92_RS03485	COG1381	Involved in DNA repair and RecF pathway recombination
HTZ92_RS03490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HTZ92_RS03500	COG4221	oxidoreductase activity
HTZ92_RS03530	COG0443	Heat shock 70 kDa protein
HTZ92_RS03540	COG0436	Aminotransferase
HTZ92_RS03560	COG0556	nucleotide-excision repair
HTZ92_RS03615	COG2070	2-Nitropropane dioxygenase
HTZ92_RS03645	COG1215	transferase activity, transferring glycosyl groups
HTZ92_RS03660	COG0415	Belongs to the DNA photolyase family
HTZ92_RS03670	COG1252	NADH dehydrogenase
HTZ92_RS03675	COG1686	Belongs to the peptidase S11 family
HTZ92_RS03690	COG1187	pseudouridine synthase activity
HTZ92_RS03715	COG0477	Major facilitator Superfamily
HTZ92_RS03720	COG0583	DNA-binding transcription factor activity
HTZ92_RS03725	COG1823	symporter activity
HTZ92_RS03735	COG0612	Peptidase, M16
HTZ92_RS03760	COG0352	thiamine-phosphate diphosphorylase activity
HTZ92_RS03795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTZ92_RS03805	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS03820	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HTZ92_RS03825	COG0076	glutamate decarboxylase activity
HTZ92_RS03835	COG1522	sequence-specific DNA binding
HTZ92_RS03840	COG3961	Belongs to the TPP enzyme family
HTZ92_RS03845	COG1113	amino acid transport
HTZ92_RS03850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HTZ92_RS03855	COG0573	inorganic phosphate transmembrane transporter activity
HTZ92_RS03865	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HTZ92_RS03870	COG0616	signal peptide processing
HTZ92_RS03905	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HTZ92_RS03910	COG1686	Belongs to the peptidase S11 family
HTZ92_RS03935	COG0583	DNA-binding transcription factor activity
HTZ92_RS03940	COG1067	ATP-dependent peptidase activity
HTZ92_RS03965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HTZ92_RS03985	COG1966	Carbon starvation protein
HTZ92_RS03990	COG2879	small protein
HTZ92_RS04020	COG1741	Belongs to the pirin family
HTZ92_RS04030	COG2964	Protein conserved in bacteria
HTZ92_RS04045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTZ92_RS04050	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ92_RS04055	COG4605	iron ion homeostasis
HTZ92_RS04060	COG4604	ABC transporter, ATP-binding protein
HTZ92_RS04065	COG4607	ABC-type enterochelin transport system periplasmic component
HTZ92_RS04070	COG4774	siderophore transport
HTZ92_RS04080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HTZ92_RS04085	COG1021	2,3-dihydroxybenzoate-AMP ligase
HTZ92_RS04090	COG1535	isochorismatase
HTZ92_RS04090	COG3433	isochorismatase activity
HTZ92_RS04100	COG1132	(ABC) transporter
HTZ92_RS04105	COG1132	(ABC) transporter
HTZ92_RS04110	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HTZ92_RS04120	COG1169	isochorismate synthase
HTZ92_RS04135	COG3739	integral membrane protein
HTZ92_RS04155	COG0302	gtp cyclohydrolase
HTZ92_RS04165	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HTZ92_RS04195	COG0308	aminopeptidase N
HTZ92_RS04200	COG0512	Glutamine amidotransferase of anthranilate synthase
HTZ92_RS04215	COG0174	glutamine synthetase
HTZ92_RS04225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HTZ92_RS04260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HTZ92_RS04265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HTZ92_RS04270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HTZ92_RS04290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HTZ92_RS04295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HTZ92_RS04300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HTZ92_RS04315	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS04320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HTZ92_RS04325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTZ92_RS04335	COG2223	nitrite transmembrane transporter activity
HTZ92_RS04345	COG0024	Methionine aminopeptidase
HTZ92_RS04350	COG0052	Belongs to the universal ribosomal protein uS2 family
HTZ92_RS04365	COG2207	Transcriptional regulator
HTZ92_RS04390	COG2951	lytic endotransglycosylase activity
HTZ92_RS04395	COG0772	Belongs to the SEDS family
HTZ92_RS04410	COG0842	Transport permease protein
HTZ92_RS04415	COG1131	(ABC) transporter
HTZ92_RS04420	COG0582	viral genome integration into host DNA
HTZ92_RS04425	COG3617	BRO family, N-terminal domain
HTZ92_RS04455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTZ92_RS04820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS04835	COG4215	(ABC) transporter
HTZ92_RS04840	COG4160	amino acid transport
HTZ92_RS04845	COG4598	ABC transporter
HTZ92_RS04855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HTZ92_RS04860	COG0826	peptidase U32
HTZ92_RS04865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ92_RS04880	COG1720	tRNA m6t6A37 methyltransferase activity
HTZ92_RS04890	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HTZ92_RS04895	COG3111	PFAM Bacterial OB fold (BOF) protein
HTZ92_RS04905	COG0642	Histidine kinase
HTZ92_RS04915	COG0494	nUDIX hydrolase
HTZ92_RS04925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HTZ92_RS04930	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HTZ92_RS04935	COG3139	Protein of unknown function (DUF1315)
HTZ92_RS04940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HTZ92_RS04945	COG1301	dicarboxylic acid transport
HTZ92_RS04950	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS04955	COG2819	hydrolase of the alpha beta superfamily
HTZ92_RS04965	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HTZ92_RS04975	COG2195	Cleaves the N-terminal amino acid of tripeptides
HTZ92_RS04980	COG1234	tRNA 3'-trailer cleavage
HTZ92_RS05010	COG2363	Small membrane protein
HTZ92_RS05030	COG0513	Belongs to the DEAD box helicase family
HTZ92_RS05040	COG0778	Nitroreductase
HTZ92_RS05070	COG1286	toxin biosynthetic process
HTZ92_RS05095	COG4783	chaperone-mediated protein folding
HTZ92_RS05100	COG1610	YqeY-like protein
HTZ92_RS05200	COG3111	PFAM Bacterial OB fold (BOF) protein
HTZ92_RS05225	COG3243	poly(R)-hydroxyalkanoic acid synthase
HTZ92_RS05230	COG0786	glutamate:sodium symporter activity
HTZ92_RS05240	COG2186	Transcriptional regulator
HTZ92_RS05295	COG0477	Major facilitator Superfamily
HTZ92_RS05300	COG1051	belongs to the nudix hydrolase family
HTZ92_RS05330	COG2995	paraquat-inducible protein a
HTZ92_RS05335	COG3008	intermembrane lipid transfer
HTZ92_RS05335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HTZ92_RS05345	COG2351	hydroxyisourate hydrolase activity
HTZ92_RS05385	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HTZ92_RS05395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HTZ92_RS05400	COG0642	Histidine kinase
HTZ92_RS05405	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS05425	COG1794	racemase activity, acting on amino acids and derivatives
HTZ92_RS05455	COG1301	dicarboxylic acid transport
HTZ92_RS05465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ92_RS05470	COG2011	ABC-type metal ion transport system permease component
HTZ92_RS05475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HTZ92_RS05480	COG1464	Belongs to the NlpA lipoprotein family
HTZ92_RS05485	COG0151	Belongs to the GarS family
HTZ92_RS05490	COG0138	bifunctional purine biosynthesis protein purh
HTZ92_RS05495	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HTZ92_RS05525	COG2308	Evidence 4 Homologs of previously reported genes of
HTZ92_RS05535	COG1305	Transglutaminase-like
HTZ92_RS05545	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HTZ92_RS05550	COG0305	Participates in initiation and elongation during chromosome replication
HTZ92_RS05575	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HTZ92_RS05585	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HTZ92_RS05590	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HTZ92_RS05615	COG0726	polysaccharide deacetylase
HTZ92_RS05615	COG1649	PFAM Uncharacterised BCR, COG1649
HTZ92_RS05620	COG1215	transferase activity, transferring glycosyl groups
HTZ92_RS05625	COG3658	cytochrome
HTZ92_RS05635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ92_RS05650	COG0583	DNA-binding transcription factor activity
HTZ92_RS05685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTZ92_RS05690	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS05715	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HTZ92_RS05720	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HTZ92_RS05730	COG2205	protein histidine kinase activity
HTZ92_RS05735	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS05740	COG0174	glutamine synthetase
HTZ92_RS05760	COG0729	surface antigen
HTZ92_RS05785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HTZ92_RS05790	COG2814	Major facilitator Superfamily
HTZ92_RS05805	COG0583	DNA-binding transcription factor activity
HTZ92_RS05820	COG1187	pseudouridine synthase activity
HTZ92_RS05840	COG0802	atpase or kinase
HTZ92_RS05845	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HTZ92_RS05855	COG1923	regulation of RNA biosynthetic process
HTZ92_RS05860	COG0697	spore germination
HTZ92_RS05875	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTZ92_RS05885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HTZ92_RS05890	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HTZ92_RS05890	COG0519	Catalyzes the synthesis of GMP from XMP
HTZ92_RS05895	COG4302	ethanolamine ammonia-lyase activity
HTZ92_RS05900	COG4303	Ethanolamine ammonia lyase large subunit
HTZ92_RS05905	COG0531	amino acid
HTZ92_RS05925	COG1454	alcohol dehydrogenase
HTZ92_RS05930	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HTZ92_RS05955	COG0308	aminopeptidase N
HTZ92_RS05995	COG1605	Chorismate mutase
HTZ92_RS06010	COG1309	transcriptional regulator
HTZ92_RS06020	COG0668	transmembrane transport
HTZ92_RS06050	COG4773	Receptor
HTZ92_RS06070	COG0488	(ABC) transporter
HTZ92_RS06075	COG0589	response to stress
HTZ92_RS06100	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HTZ92_RS06110	COG3135	benzoate transporter
HTZ92_RS06115	COG1522	sequence-specific DNA binding
HTZ92_RS06125	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HTZ92_RS06130	COG0583	DNA-binding transcription factor activity
HTZ92_RS06140	COG0183	Belongs to the thiolase family
HTZ92_RS06150	COG2030	dehydratase
HTZ92_RS06170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HTZ92_RS06185	COG0824	Thioesterase
HTZ92_RS06190	COG1454	alcohol dehydrogenase
HTZ92_RS06200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HTZ92_RS06220	COG0069	glutamate synthase activity
HTZ92_RS06240	COG2814	Major facilitator Superfamily
HTZ92_RS06255	COG0511	ligase activity, forming carbon-carbon bonds
HTZ92_RS06275	COG1116	anion transmembrane transporter activity
HTZ92_RS06275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTZ92_RS06280	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS06290	COG2146	nitrite reductase [NAD(P)H] activity
HTZ92_RS06290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTZ92_RS06295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTZ92_RS06300	COG0243	molybdopterin cofactor binding
HTZ92_RS06315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HTZ92_RS06330	COG0521	Mo-molybdopterin cofactor biosynthetic process
HTZ92_RS06330	COG0315	cyclic pyranopterin monophosphate synthase activity
HTZ92_RS06335	COG0303	'Molybdopterin
HTZ92_RS06345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ92_RS06350	COG0697	spore germination
HTZ92_RS06370	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HTZ92_RS06375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HTZ92_RS06430	COG2204	response regulator
HTZ92_RS06435	COG3852	Histidine kinase
HTZ92_RS06460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HTZ92_RS06465	COG0575	Belongs to the CDS family
HTZ92_RS06500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTZ92_RS06515	COG2137	regulation of response to DNA damage stimulus
HTZ92_RS06525	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HTZ92_RS06530	COG1011	Hydrolase
HTZ92_RS06555	COG1522	sequence-specific DNA binding
HTZ92_RS06565	COG1113	amino acid transport
HTZ92_RS06580	COG0659	secondary active sulfate transmembrane transporter activity
HTZ92_RS06585	COG2135	peptidase activity
HTZ92_RS06600	COG5001	Diguanylate cyclase
HTZ92_RS06600	COG3300	MHYT domain
HTZ92_RS06620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ92_RS06620	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HTZ92_RS06620	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HTZ92_RS06625	COG1105	Belongs to the carbohydrate kinase PfkB family
HTZ92_RS06630	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HTZ92_RS06630	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ92_RS06660	COG0024	Methionine aminopeptidase
HTZ92_RS06665	COG0583	DNA-binding transcription factor activity
HTZ92_RS06675	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HTZ92_RS06680	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HTZ92_RS06685	COG0516	GMP reductase activity
HTZ92_RS06685	COG0517	IMP dehydrogenase activity
HTZ92_RS06710	COG0552	protein localization to endoplasmic reticulum
HTZ92_RS06720	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HTZ92_RS06730	COG4890	Cyd operon protein YbgT
HTZ92_RS06735	COG1294	oxidase, subunit
HTZ92_RS06750	COG1585	Membrane protein implicated in regulation of membrane protease activity
HTZ92_RS06760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HTZ92_RS06765	COG4774	siderophore transport
HTZ92_RS06780	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HTZ92_RS06785	COG0569	domain protein
HTZ92_RS06790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HTZ92_RS06820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HTZ92_RS06825	COG0542	response to heat
HTZ92_RS06850	COG1902	pentaerythritol trinitrate reductase activity
HTZ92_RS06850	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTZ92_RS06895	COG2323	membrane
HTZ92_RS06900	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HTZ92_RS06910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTZ92_RS06915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTZ92_RS06920	COG0183	Belongs to the thiolase family
HTZ92_RS06925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HTZ92_RS06930	COG0596	Alpha beta hydrolase
HTZ92_RS06935	COG2271	Major facilitator Superfamily
HTZ92_RS06940	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HTZ92_RS06945	COG3485	protocatechuate 3,4-dioxygenase
HTZ92_RS06950	COG3485	protocatechuate 3,4-dioxygenase
HTZ92_RS06955	COG0710	3-dehydroquinate dehydratase activity
HTZ92_RS06960	COG3420	alginic acid biosynthetic process
HTZ92_RS06965	COG3659	wide pore channel activity
HTZ92_RS06970	COG4993	Dehydrogenase
HTZ92_RS06980	COG2391	methyltransferase activity
HTZ92_RS06995	COG1414	Transcriptional regulator
HTZ92_RS07000	COG0583	DNA-binding transcription factor activity
HTZ92_RS07005	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS07030	COG2814	Major facilitator Superfamily
HTZ92_RS07040	COG0154	amidase activity
HTZ92_RS07060	COG4638	Rieske (2fe-2S)
HTZ92_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07080	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS07090	COG3733	amine oxidase
HTZ92_RS07100	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS07110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTZ92_RS07115	COG0183	Belongs to the thiolase family
HTZ92_RS07120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTZ92_RS07125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTZ92_RS07135	COG4829	muconolactone delta-isomerase
HTZ92_RS07140	COG4948	Mandelate Racemase Muconate Lactonizing
HTZ92_RS07145	COG0583	DNA-binding transcription factor activity
HTZ92_RS07155	COG2186	Transcriptional regulator
HTZ92_RS07175	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS07190	COG1902	pentaerythritol trinitrate reductase activity
HTZ92_RS07190	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTZ92_RS07205	COG0789	Transcriptional regulator
HTZ92_RS07230	COG1309	transcriptional regulator
HTZ92_RS07235	COG0583	DNA-binding transcription factor activity
HTZ92_RS07240	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07250	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07260	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS07270	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ92_RS07290	COG2831	hemolysin activation secretion protein
HTZ92_RS07295	COG3210	domain, Protein
HTZ92_RS07330	COG2188	Transcriptional regulator
HTZ92_RS07345	COG0583	DNA-binding transcription factor activity
HTZ92_RS07360	COG1566	PFAM secretion protein HlyD family protein
HTZ92_RS07375	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS07380	COG0129	dihydroxy-acid dehydratase activity
HTZ92_RS07390	COG0583	DNA-binding transcription factor activity
HTZ92_RS07395	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HTZ92_RS07405	COG2084	Dehydrogenase
HTZ92_RS07410	COG2207	Transcriptional regulator
HTZ92_RS07425	COG1064	alcohol dehydrogenase
HTZ92_RS07435	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HTZ92_RS07440	COG1120	ATPase activity
HTZ92_RS07460	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HTZ92_RS07505	COG1401	restriction endodeoxyribonuclease activity
HTZ92_RS07575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HTZ92_RS07625	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HTZ92_RS07640	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07655	COG2207	Transcriptional regulator
HTZ92_RS07665	COG2205	protein histidine kinase activity
HTZ92_RS07670	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS07675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS07680	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HTZ92_RS07720	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HTZ92_RS07730	COG0753	catalase activity
HTZ92_RS07745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HTZ92_RS07805	COG1535	isochorismatase
HTZ92_RS07805	COG3433	isochorismatase activity
HTZ92_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07815	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HTZ92_RS07820	COG4149	molybdate abc transporter
HTZ92_RS07825	COG0725	ABC transporter, periplasmic molybdate-binding protein
HTZ92_RS07835	COG4638	Rieske (2fe-2S)
HTZ92_RS07840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HTZ92_RS07845	COG0543	2 iron, 2 sulfur cluster binding
HTZ92_RS07845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTZ92_RS07860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS07870	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07885	COG2207	Transcriptional regulator
HTZ92_RS07890	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS07895	COG2610	gluconate transmembrane transporter activity
HTZ92_RS07905	COG1309	transcriptional regulator
HTZ92_RS07925	COG0583	DNA-binding transcription factor activity
HTZ92_RS07940	COG2031	fatty acid transporter
HTZ92_RS07945	COG0183	Belongs to the thiolase family
HTZ92_RS07950	COG0583	DNA-binding transcription factor activity
HTZ92_RS07955	COG0583	DNA-binding transcription factor activity
HTZ92_RS07970	COG1027	Aspartate ammonia-lyase
HTZ92_RS07980	COG0477	Major facilitator Superfamily
HTZ92_RS08000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTZ92_RS08005	COG4521	taurine ABC transporter
HTZ92_RS08020	COG2188	Transcriptional regulator
HTZ92_RS08030	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HTZ92_RS08035	COG1733	regulation of RNA biosynthetic process
HTZ92_RS08040	COG3708	Transcriptional regulator
HTZ92_RS08040	COG2207	Transcriptional regulator
HTZ92_RS08055	COG0730	response to heat
HTZ92_RS08065	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ92_RS08065	COG3453	Protein conserved in bacteria
HTZ92_RS08075	COG3781	membrane
HTZ92_RS08080	COG1063	alcohol dehydrogenase
HTZ92_RS08090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HTZ92_RS08095	COG0508	dehydrogenase complex catalyzes the overall conversion of
HTZ92_RS08100	COG0022	dehydrogenase e1 component
HTZ92_RS08105	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HTZ92_RS08110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HTZ92_RS08125	COG3706	GGDEF domain
HTZ92_RS08145	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HTZ92_RS08170	COG2226	methyltransferase
HTZ92_RS08225	COG0842	Transport permease protein
HTZ92_RS08230	COG0842	Transport permease protein
HTZ92_RS08235	COG1131	(ABC) transporter
HTZ92_RS08250	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HTZ92_RS08255	COG4773	Receptor
HTZ92_RS08275	COG0730	response to heat
HTZ92_RS08280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HTZ92_RS08295	COG0406	alpha-ribazole phosphatase activity
HTZ92_RS08315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HTZ92_RS08345	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HTZ92_RS08355	COG4264	IucA IucC family
HTZ92_RS08360	COG4264	IucA IucC family
HTZ92_RS08380	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HTZ92_RS08395	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS08400	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS08405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HTZ92_RS08410	COG2207	Transcriptional regulator
HTZ92_RS08415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HTZ92_RS08420	COG0776	regulation of translation
HTZ92_RS08445	COG0822	iron-sulfur transferase activity
HTZ92_RS08450	COG0316	Belongs to the HesB IscA family
HTZ92_RS08480	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HTZ92_RS08500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HTZ92_RS08505	COG0702	epimerase
HTZ92_RS08540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HTZ92_RS08550	COG0339	signal peptide processing
HTZ92_RS08570	COG4206	TonB-dependent receptor
HTZ92_RS08600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HTZ92_RS08605	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HTZ92_RS08635	COG0776	regulation of translation
HTZ92_RS08700	COG0084	hydrolase, TatD family'
HTZ92_RS08720	COG1663	tetraacyldisaccharide 4'-kinase activity
HTZ92_RS08725	COG1132	(ABC) transporter
HTZ92_RS08735	COG0811	peptide transport
HTZ92_RS08740	COG1475	DNA binding
HTZ92_RS08745	COG1192	Involved in chromosome partitioning
HTZ92_RS08755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HTZ92_RS08770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HTZ92_RS08775	COG0191	fructose-bisphosphate aldolase activity
HTZ92_RS08795	COG0424	maF-like protein
HTZ92_RS08800	COG2850	peptidyl-arginine hydroxylation
HTZ92_RS08810	COG0640	Transcriptional regulator
HTZ92_RS08820	COG3619	membrane
HTZ92_RS08825	COG3122	Protein conserved in bacteria
HTZ92_RS08830	COG1132	(ABC) transporter
HTZ92_RS08850	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HTZ92_RS08855	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HTZ92_RS08865	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HTZ92_RS08865	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HTZ92_RS08865	COG0506	proline dehydrogenase activity
HTZ92_RS08870	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HTZ92_RS08885	COG3698	Phosphodiester glycosidase
HTZ92_RS08895	COG2353	YceI-like domain
HTZ92_RS08905	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HTZ92_RS08950	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HTZ92_RS08950	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HTZ92_RS08975	COG3539	Fimbrial protein
HTZ92_RS08980	COG3121	Chaperone
HTZ92_RS09005	COG0697	spore germination
HTZ92_RS09015	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HTZ92_RS09025	COG0583	DNA-binding transcription factor activity
HTZ92_RS09055	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HTZ92_RS09065	COG1061	Type III restriction enzyme res subunit
HTZ92_RS09070	COG1002	Type II restriction enzyme, methylase subunits
HTZ92_RS09085	COG4584	PFAM Integrase catalytic
HTZ92_RS09090	COG1484	DNA-dependent DNA replication
HTZ92_RS09095	COG1309	transcriptional regulator
HTZ92_RS09110	COG1522	sequence-specific DNA binding
HTZ92_RS09120	COG1126	abc transporter atp-binding protein
HTZ92_RS09125	COG0765	amino acid transport
HTZ92_RS09130	COG0765	amino acid transport
HTZ92_RS09160	COG1464	Belongs to the NlpA lipoprotein family
HTZ92_RS09170	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HTZ92_RS09175	COG2011	ABC-type metal ion transport system permease component
HTZ92_RS09180	COG0012	GTP binding
HTZ92_RS09205	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HTZ92_RS09245	COG0386	Belongs to the glutathione peroxidase family
HTZ92_RS09255	COG0436	Aminotransferase
HTZ92_RS09295	COG3634	alkyl hydroperoxide reductase activity
HTZ92_RS09310	COG0583	DNA-binding transcription factor activity
HTZ92_RS09315	COG0798	PFAM Bile acid sodium symporter
HTZ92_RS09320	COG0640	Transcriptional regulator
HTZ92_RS09335	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HTZ92_RS09345	COG0583	DNA-binding transcription factor activity
HTZ92_RS09355	COG1953	Uracil, thiamine, allantoin
HTZ92_RS09365	COG2175	clavaminate synthase activity
HTZ92_RS09370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTZ92_RS09375	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HTZ92_RS09380	COG4521	taurine ABC transporter
HTZ92_RS09390	COG0477	Major facilitator Superfamily
HTZ92_RS09410	COG1271	oxidase subunit
HTZ92_RS09415	COG1294	oxidase, subunit
HTZ92_RS09425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ92_RS09465	COG3052	prosthetic group binding
HTZ92_RS09480	COG0583	DNA-binding transcription factor activity
HTZ92_RS09490	COG2814	Major facilitator Superfamily
HTZ92_RS09510	COG1346	cytolysis
HTZ92_RS09520	COG0583	DNA-binding transcription factor activity
HTZ92_RS09525	COG0625	glutathione transferase activity
HTZ92_RS09530	COG0625	glutathione transferase activity
HTZ92_RS09535	COG0583	DNA-binding transcription factor activity
HTZ92_RS09550	COG1045	serine acetyltransferase
HTZ92_RS09555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HTZ92_RS09560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HTZ92_RS09565	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS09580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTZ92_RS09585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTZ92_RS09590	COG1126	abc transporter atp-binding protein
HTZ92_RS09595	COG0765	amino acid transport
HTZ92_RS09600	COG0765	amino acid transport
HTZ92_RS09620	COG2205	protein histidine kinase activity
HTZ92_RS09620	COG0784	Response regulator, receiver
HTZ92_RS09640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HTZ92_RS09660	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS09710	COG0583	DNA-binding transcription factor activity
HTZ92_RS09730	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ92_RS09735	COG1309	transcriptional regulator
HTZ92_RS09740	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS09745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HTZ92_RS09750	COG1024	Enoyl-CoA hydratase
HTZ92_RS09755	COG4770	biotin carboxylase activity
HTZ92_RS09765	COG0583	DNA-binding transcription factor activity
HTZ92_RS09780	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS09790	COG2814	Major facilitator Superfamily
HTZ92_RS09800	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HTZ92_RS09805	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HTZ92_RS09810	COG2814	Major facilitator Superfamily
HTZ92_RS09815	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS09820	COG1024	Enoyl-CoA hydratase
HTZ92_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS09830	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTZ92_RS09835	COG0183	Belongs to the thiolase family
HTZ92_RS09845	COG2814	Major facilitator Superfamily
HTZ92_RS09855	COG1024	Enoyl-CoA hydratase
HTZ92_RS09870	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS09875	COG2814	Major facilitator Superfamily
HTZ92_RS09880	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HTZ92_RS09885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HTZ92_RS09900	COG3842	ATPase activity
HTZ92_RS09905	COG1840	ABC-type Fe3 transport system, periplasmic component
HTZ92_RS09915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTZ92_RS09920	COG1414	Transcriptional regulator
HTZ92_RS09930	COG0583	DNA-binding transcription factor activity
HTZ92_RS09935	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HTZ92_RS09940	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS09950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HTZ92_RS09960	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS09965	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ92_RS09970	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS09975	COG2267	carboxylic ester hydrolase activity
HTZ92_RS09995	COG3038	cytochrome b561
HTZ92_RS10000	COG0753	catalase activity
HTZ92_RS10005	COG2271	Major facilitator Superfamily
HTZ92_RS10010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HTZ92_RS10015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HTZ92_RS10030	COG2207	Transcriptional regulator
HTZ92_RS10070	COG2050	protein possibly involved in aromatic compounds catabolism
HTZ92_RS10080	COG3327	negative regulation of DNA-templated transcription, initiation
HTZ92_RS10085	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HTZ92_RS10090	COG0183	Belongs to the thiolase family
HTZ92_RS10095	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTZ92_RS10100	COG1024	Enoyl-CoA hydratase
HTZ92_RS10105	COG1024	Enoyl-CoA hydratase
HTZ92_RS10110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTZ92_RS10115	COG2151	metal-sulfur cluster biosynthetic enzyme
HTZ92_RS10120	COG3396	Phenylacetate-CoA oxygenase
HTZ92_RS10125	COG3460	Phenylacetate-CoA oxygenase
HTZ92_RS10130	COG3396	Phenylacetate-CoA oxygenase
HTZ92_RS10135	COG2030	dehydratase
HTZ92_RS10135	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS10140	COG1760	l-serine dehydratase
HTZ92_RS10145	COG0531	amino acid
HTZ92_RS10150	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS10195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTZ92_RS10215	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HTZ92_RS10230	COG2807	transmembrane transport
HTZ92_RS10235	COG0590	tRNA wobble adenosine to inosine editing
HTZ92_RS10350	COG1116	anion transmembrane transporter activity
HTZ92_RS10355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HTZ92_RS10365	COG0864	Transcriptional regulator
HTZ92_RS10380	COG1733	regulation of RNA biosynthetic process
HTZ92_RS10385	COG2249	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS10390	COG0439	Biotin carboxylase
HTZ92_RS10405	COG1063	alcohol dehydrogenase
HTZ92_RS10415	COG1309	transcriptional regulator
HTZ92_RS10430	COG3210	domain, Protein
HTZ92_RS10435	COG2831	hemolysin activation secretion protein
HTZ92_RS10440	COG0038	chloride channel
HTZ92_RS10445	COG4770	biotin carboxylase activity
HTZ92_RS10465	COG1914	H( )-stimulated, divalent metal cation uptake system
HTZ92_RS10470	COG0583	DNA-binding transcription factor activity
HTZ92_RS10505	COG1250	3-hydroxyacyl-CoA dehydrogenase
HTZ92_RS10525	COG2814	Major facilitator Superfamily
HTZ92_RS10535	COG1560	Kdo2-lipid A biosynthetic process
HTZ92_RS10550	COG1522	sequence-specific DNA binding
HTZ92_RS10565	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HTZ92_RS10575	COG4122	O-methyltransferase activity
HTZ92_RS10650	COG1137	ATPase activity
HTZ92_RS10655	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HTZ92_RS10665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HTZ92_RS10670	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HTZ92_RS10670	COG0517	IMP dehydrogenase activity
HTZ92_RS10875	COG5377	YqaJ viral recombinase family
HTZ92_RS10885	COG0210	DNA helicase
HTZ92_RS10965	COG2814	Major facilitator Superfamily
HTZ92_RS11000	COG1278	Cold shock
HTZ92_RS11005	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS11035	COG1570	exodeoxyribonuclease VII activity
HTZ92_RS11085	COG0583	DNA-binding transcription factor activity
HTZ92_RS11090	COG4638	Rieske (2fe-2S)
HTZ92_RS11095	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HTZ92_RS11100	COG0543	2 iron, 2 sulfur cluster binding
HTZ92_RS11100	COG0633	Ferredoxin
HTZ92_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS11110	COG3135	benzoate transporter
HTZ92_RS11115	COG2814	Major facilitator Superfamily
HTZ92_RS11130	COG1643	Atp-dependent helicase
HTZ92_RS11135	COG0450	alkyl hydroperoxide reductase
HTZ92_RS11145	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HTZ92_RS11155	COG3634	alkyl hydroperoxide reductase activity
HTZ92_RS11175	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HTZ92_RS11195	COG0625	glutathione transferase activity
HTZ92_RS11205	COG2885	chlorophyll binding
HTZ92_RS11240	COG0542	response to heat
HTZ92_RS11255	COG1765	OsmC-like protein
HTZ92_RS11270	COG0667	Aldo Keto reductase
HTZ92_RS11285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HTZ92_RS11295	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HTZ92_RS11305	COG0582	viral genome integration into host DNA
HTZ92_RS11430	COG3566	protein conserved in bacteria
HTZ92_RS11450	COG3567	Phage-associated protein, HI1409 family
HTZ92_RS11455	COG5410	chromosome segregation
HTZ92_RS11535	COG4197	protein conserved in bacteria, prophage-related
HTZ92_RS11540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HTZ92_RS11595	COG0527	aspartate kinase activity
HTZ92_RS11605	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HTZ92_RS11615	COG3038	cytochrome b561
HTZ92_RS11620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HTZ92_RS11625	COG2252	PERMEase
HTZ92_RS11635	COG2072	flavoprotein involved in K transport
HTZ92_RS11650	COG1741	Belongs to the pirin family
HTZ92_RS11655	COG1309	transcriptional regulator
HTZ92_RS11665	COG0300	oxidoreductase activity
HTZ92_RS11670	COG2072	flavoprotein involved in K transport
HTZ92_RS11675	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HTZ92_RS11720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HTZ92_RS11735	COG2814	Major facilitator Superfamily
HTZ92_RS11740	COG1024	Enoyl-CoA hydratase
HTZ92_RS11745	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS11755	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS11780	COG2186	Transcriptional regulator
HTZ92_RS11785	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS11795	COG4948	Mandelate Racemase Muconate Lactonizing
HTZ92_RS11800	COG2271	Major facilitator Superfamily
HTZ92_RS11805	COG2721	sulfolactate sulfo-lyase activity
HTZ92_RS11810	COG0697	spore germination
HTZ92_RS11850	COG1113	amino acid transport
HTZ92_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS11890	COG0531	amino acid
HTZ92_RS11900	COG1113	amino acid transport
HTZ92_RS11940	COG4269	membrane
HTZ92_RS11955	COG1309	transcriptional regulator
HTZ92_RS11980	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HTZ92_RS11990	COG2184	nucleotidyltransferase activity
HTZ92_RS12050	COG0789	Transcriptional regulator
HTZ92_RS12125	COG0582	viral genome integration into host DNA
HTZ92_RS12135	COG1902	pentaerythritol trinitrate reductase activity
HTZ92_RS12135	COG0446	pyridine nucleotide-disulphide oxidoreductase
HTZ92_RS12145	COG3706	GGDEF domain
HTZ92_RS12145	COG2203	Gaf domain
HTZ92_RS12145	COG5001	Diguanylate cyclase
HTZ92_RS12145	COG4251	negative regulation of phosphorylation
HTZ92_RS12155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTZ92_RS12175	COG4172	Belongs to the ABC transporter superfamily
HTZ92_RS12180	COG4239	(ABC) transporter, permease
HTZ92_RS12185	COG4174	ABC transporter (Permease)
HTZ92_RS12195	COG1388	LysM domain
HTZ92_RS12195	COG0741	lytic transglycosylase activity
HTZ92_RS12195	COG1388	LysM domain
HTZ92_RS12195	COG0741	lytic transglycosylase activity
HTZ92_RS12200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HTZ92_RS12240	COG0583	DNA-binding transcription factor activity
HTZ92_RS12245	COG1279	arginine transmembrane transporter activity
HTZ92_RS12265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTZ92_RS12270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTZ92_RS12275	COG0006	proline dipeptidase activity
HTZ92_RS12315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HTZ92_RS12340	COG3384	dioxygenase
HTZ92_RS12350	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HTZ92_RS12355	COG2878	Part of a membrane complex involved in electron transport
HTZ92_RS12360	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HTZ92_RS12385	COG0768	penicillin binding
HTZ92_RS12390	COG0742	ribosomal rna small subunit methyltransferase
HTZ92_RS12405	COG0830	nickel cation binding
HTZ92_RS12415	COG0804	urea catabolic process
HTZ92_RS12455	COG1253	flavin adenine dinucleotide binding
HTZ92_RS12460	COG2851	Citrate transporter
HTZ92_RS12510	COG1773	rubredoxin
HTZ92_RS12515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HTZ92_RS12525	COG0583	DNA-binding transcription factor activity
HTZ92_RS12555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HTZ92_RS12560	COG4181	ATPase activity
HTZ92_RS12605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HTZ92_RS12625	COG0306	phosphate transporter
HTZ92_RS12635	COG3958	Transketolase
HTZ92_RS12640	COG3959	Transketolase, thiamine diphosphate binding domain
HTZ92_RS12645	COG2271	Major facilitator Superfamily
HTZ92_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS12655	COG0583	DNA-binding transcription factor activity
HTZ92_RS12670	COG2223	nitrite transmembrane transporter activity
HTZ92_RS12675	COG2207	Transcriptional regulator
HTZ92_RS12680	COG2066	Belongs to the glutaminase family
HTZ92_RS12685	COG0242	peptide deformylase activity
HTZ92_RS12690	COG0477	Major facilitator Superfamily
HTZ92_RS12700	COG0028	Belongs to the TPP enzyme family
HTZ92_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS12720	COG2267	carboxylic ester hydrolase activity
HTZ92_RS12730	COG2271	Major facilitator Superfamily
HTZ92_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS12765	COG1414	Transcriptional regulator
HTZ92_RS12780	COG1024	Enoyl-CoA hydratase
HTZ92_RS12790	COG1215	transferase activity, transferring glycosyl groups
HTZ92_RS12795	COG0726	polysaccharide deacetylase
HTZ92_RS12795	COG1649	PFAM Uncharacterised BCR, COG1649
HTZ92_RS12805	COG4681	YaeQ
HTZ92_RS12815	COG0523	cobalamin synthesis protein
HTZ92_RS12825	COG1607	acyl-coa hydrolase
HTZ92_RS12835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ92_RS12840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ92_RS12845	COG1309	transcriptional regulator
HTZ92_RS12870	COG2040	homocysteine
HTZ92_RS12875	COG0531	amino acid
HTZ92_RS12920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTZ92_RS12925	COG0477	Major facilitator Superfamily
HTZ92_RS13055	COG0629	single-stranded DNA binding
HTZ92_RS13100	COG0582	viral genome integration into host DNA
HTZ92_RS13110	COG0405	Gamma-glutamyltransferase
HTZ92_RS13115	COG2814	Major facilitator Superfamily
HTZ92_RS13125	COG2050	protein possibly involved in aromatic compounds catabolism
HTZ92_RS13140	COG1090	epimerase
HTZ92_RS13160	COG0420	3'-5' exonuclease activity
HTZ92_RS13185	COG0735	belongs to the Fur family
HTZ92_RS13190	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HTZ92_RS13210	COG0121	glutamine amidotransferase
HTZ92_RS13225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTZ92_RS13235	COG0210	DNA helicase
HTZ92_RS13240	COG2885	chlorophyll binding
HTZ92_RS13245	COG0204	Acyl-transferase
HTZ92_RS13260	COG2894	cell division
HTZ92_RS13275	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS13280	COG1674	ftsk spoiiie
HTZ92_RS13285	COG0492	ferredoxin-NADP+ reductase activity
HTZ92_RS13290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HTZ92_RS13300	COG0456	acetyltransferase
HTZ92_RS13345	COG1981	membrane
HTZ92_RS13360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HTZ92_RS13360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HTZ92_RS13380	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS13390	COG0657	acetylesterase activity
HTZ92_RS13400	COG0473	3-isopropylmalate dehydrogenase activity
HTZ92_RS13405	COG0583	DNA-binding transcription factor activity
HTZ92_RS13425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HTZ92_RS13450	COG0564	pseudouridine synthase activity
HTZ92_RS13460	COG0358	DNA primase activity
HTZ92_RS13475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HTZ92_RS13495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HTZ92_RS13525	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HTZ92_RS13535	COG0351	phosphomethylpyrimidine kinase
HTZ92_RS13535	COG0352	thiamine-phosphate diphosphorylase activity
HTZ92_RS13535	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HTZ92_RS13540	COG1652	LysM domain
HTZ92_RS13565	COG1399	metal-binding, possibly nucleic acid-binding protein
HTZ92_RS13570	COG3101	peptidyl-lysine hydroxylation
HTZ92_RS13575	COG0009	L-threonylcarbamoyladenylate synthase
HTZ92_RS13580	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HTZ92_RS13585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HTZ92_RS13600	COG4106	trans-aconitate 2-methyltransferase activity
HTZ92_RS13615	COG0596	Alpha beta hydrolase
HTZ92_RS13615	COG2226	methyltransferase
HTZ92_RS13615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTZ92_RS13620	COG1877	trehalose-phosphatase activity
HTZ92_RS13625	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HTZ92_RS13630	COG2223	nitrite transmembrane transporter activity
HTZ92_RS13650	COG1196	nuclear chromosome segregation
HTZ92_RS13660	COG0730	response to heat
HTZ92_RS13675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HTZ92_RS13685	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HTZ92_RS13730	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HTZ92_RS13735	COG0489	protein tyrosine kinase activity
HTZ92_RS13745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTZ92_RS13745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTZ92_RS13775	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HTZ92_RS13780	COG2081	HI0933 family
HTZ92_RS13790	COG0668	transmembrane transport
HTZ92_RS13810	COG0583	DNA-binding transcription factor activity
HTZ92_RS13830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HTZ92_RS13835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HTZ92_RS13865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HTZ92_RS13905	COG0745	RESPONSE REGULATOR receiver
HTZ92_RS13925	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HTZ92_RS13980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS13995	COG0583	DNA-binding transcription factor activity
HTZ92_RS14005	COG0583	DNA-binding transcription factor activity
HTZ92_RS14020	COG0583	DNA-binding transcription factor activity
HTZ92_RS14025	COG1053	succinate dehydrogenase
HTZ92_RS14040	COG1309	transcriptional regulator
HTZ92_RS14045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HTZ92_RS14050	COG2814	Major facilitator Superfamily
HTZ92_RS14055	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS14060	COG0583	DNA-binding transcription factor activity
HTZ92_RS14065	COG1063	alcohol dehydrogenase
HTZ92_RS14095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HTZ92_RS14100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HTZ92_RS14105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HTZ92_RS14125	COG2132	Multicopper oxidase
HTZ92_RS14135	COG0561	phosphatase activity
HTZ92_RS14140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HTZ92_RS14150	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HTZ92_RS14165	COG1214	PFAM Peptidase M22, glycoprotease
HTZ92_RS14215	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HTZ92_RS14225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HTZ92_RS14230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HTZ92_RS14235	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HTZ92_RS14295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HTZ92_RS14305	COG1846	Transcriptional regulator
HTZ92_RS14310	COG1764	response to oxidative stress
HTZ92_RS14335	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HTZ92_RS14335	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HTZ92_RS14350	COG0037	tRNA processing
HTZ92_RS14360	COG0248	Ppx GppA phosphatase
HTZ92_RS14390	COG0072	phenylalanine-tRNA ligase activity
HTZ92_RS14430	COG1238	metal cluster binding
HTZ92_RS14435	COG0625	glutathione transferase activity
HTZ92_RS14450	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ92_RS14455	COG3028	Belongs to the UPF0307 family
HTZ92_RS14460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HTZ92_RS14480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HTZ92_RS14485	COG0617	tRNA 3'-terminal CCA addition
HTZ92_RS14490	COG1555	photosystem II stabilization
HTZ92_RS14495	COG3956	TIGRFAM MazG family protein
HTZ92_RS14505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HTZ92_RS14525	COG5002	protein histidine kinase activity
HTZ92_RS14525	COG2205	protein histidine kinase activity
HTZ92_RS14525	COG0784	Response regulator, receiver
HTZ92_RS14530	COG1024	Enoyl-CoA hydratase
HTZ92_RS14535	COG2084	Dehydrogenase
HTZ92_RS14540	COG3622	Belongs to the hyi family
HTZ92_RS14570	COG0697	spore germination
HTZ92_RS14580	COG2814	Major facilitator Superfamily
HTZ92_RS14585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HTZ92_RS14595	COG0583	DNA-binding transcription factor activity
HTZ92_RS14605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HTZ92_RS14620	COG0084	hydrolase, TatD family'
HTZ92_RS14635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HTZ92_RS14665	COG0440	acetolactate synthase activity
HTZ92_RS14670	COG0028	Belongs to the TPP enzyme family
HTZ92_RS14695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS14700	COG1136	(ABC) transporter
HTZ92_RS14700	COG0577	efflux transmembrane transporter activity
HTZ92_RS14705	COG1538	Outer membrane efflux protein
HTZ92_RS14720	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HTZ92_RS14725	COG1162	GTPase activity
HTZ92_RS14735	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HTZ92_RS14775	COG1426	Protein conserved in bacteria
HTZ92_RS14810	COG0793	Belongs to the peptidase S41A family
HTZ92_RS14825	COG2267	carboxylic ester hydrolase activity
HTZ92_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
HTZ92_RS14840	COG3265	gluconokinase activity
HTZ92_RS14850	COG0800	Aldolase
HTZ92_RS14860	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HTZ92_RS14865	COG0280	phosphate acetyltransferase
HTZ92_RS14865	COG0857	belongs to the CobB CobQ family
HTZ92_RS14870	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HTZ92_RS14870	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HTZ92_RS14890	COG0740	serine-type endopeptidase activity
HTZ92_RS14900	COG4774	siderophore transport
HTZ92_RS14910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HTZ92_RS14920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HTZ92_RS14920	COG2813	Specifically methylates the guanine in position
HTZ92_RS15070	COG0788	formyltetrahydrofolate deformylase activity
HTZ92_RS15095	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HTZ92_RS15095	COG4651	solute:proton antiporter activity
HTZ92_RS15115	COG0724	RNA recognition motif
HTZ92_RS15120	COG0210	DNA helicase
HTZ92_RS15145	COG1733	regulation of RNA biosynthetic process
HTZ92_RS15155	COG2900	Belongs to the SlyX family
HTZ92_RS15160	COG0488	(ABC) transporter
HTZ92_RS15165	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS15170	COG1560	Kdo2-lipid A biosynthetic process
HTZ92_RS15180	COG1301	dicarboxylic acid transport
HTZ92_RS15235	COG0473	3-isopropylmalate dehydrogenase activity
HTZ92_RS15300	COG0583	DNA-binding transcription factor activity
HTZ92_RS15310	COG0625	glutathione transferase activity
HTZ92_RS15315	COG2378	regulation of single-species biofilm formation
HTZ92_RS15320	COG0546	phosphoglycolate phosphatase activity
HTZ92_RS15330	COG1530	ribonuclease E activity
HTZ92_RS15335	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ92_RS15350	COG0583	DNA-binding transcription factor activity
HTZ92_RS15355	COG4221	oxidoreductase activity
HTZ92_RS15360	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HTZ92_RS15370	COG0534	Mate efflux family protein
HTZ92_RS15385	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HTZ92_RS15410	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
HTZ92_RS15410	COG0493	'glutamate synthase
HTZ92_RS15420	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HTZ92_RS15425	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HTZ92_RS15440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HTZ92_RS15450	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HTZ92_RS15450	COG0644	oxidoreductase
HTZ92_RS15455	COG0425	Belongs to the sulfur carrier protein TusA family
HTZ92_RS15460	COG4535	Mg2 and Co2 transporter CorC
HTZ92_RS15470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HTZ92_RS15490	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HTZ92_RS15495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HTZ92_RS15495	COG0475	glutathione-regulated potassium exporter activity
HTZ92_RS15510	COG0484	heat shock protein binding
HTZ92_RS15515	COG0789	Transcriptional regulator
HTZ92_RS15520	COG0598	Magnesium transport protein CorA
HTZ92_RS15535	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
HTZ92_RS15540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HTZ92_RS15545	COG1074	ATP-dependent DNA helicase activity
HTZ92_RS15550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HTZ92_RS15570	COG2226	methyltransferase
HTZ92_RS15585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTZ92_RS15590	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HTZ92_RS15605	COG2111	Na H antiporter
HTZ92_RS15605	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HTZ92_RS15610	COG1006	Multisubunit Na H antiporter MnhC subunit
HTZ92_RS15615	COG0651	ATP synthesis coupled electron transport
HTZ92_RS15620	COG1863	multisubunit Na H antiporter MnhE subunit
HTZ92_RS15625	COG2212	antiporter activity
HTZ92_RS15630	COG1320	monovalent cation:proton antiporter activity
HTZ92_RS15645	COG0195	Participates in both transcription termination and antitermination
HTZ92_RS15690	COG0237	dephospho-CoA kinase activity
HTZ92_RS15700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HTZ92_RS15715	COG0497	DNA recombination
HTZ92_RS15725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HTZ92_RS15755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HTZ92_RS15755	COG2169	Transcriptional regulator
HTZ92_RS15760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HTZ92_RS15820	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HTZ92_RS15835	COG0326	Molecular chaperone. Has ATPase activity
HTZ92_RS15850	COG2056	Na+-H+ antiporter family
HTZ92_RS15950	COG0546	phosphoglycolate phosphatase activity
HTZ92_RS15955	COG1716	ATPase activity
HTZ92_RS16000	COG0181	hydroxymethylbilane synthase activity
HTZ92_RS16010	COG3275	phosphorelay sensor kinase activity
HTZ92_RS16030	COG1538	Outer membrane efflux protein
HTZ92_RS16035	COG0697	spore germination
HTZ92_RS16060	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HTZ92_RS16065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HTZ92_RS16070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HTZ92_RS16075	COG0772	Belongs to the SEDS family
HTZ92_RS16100	COG4974	Belongs to the 'phage' integrase family
HTZ92_RS16105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTZ92_RS16115	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HTZ92_RS16125	COG2197	response regulator
HTZ92_RS16140	COG0793	Belongs to the peptidase S41A family
HTZ92_RS16145	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HTZ92_RS16150	COG0795	lipopolysaccharide-transporting ATPase activity
HTZ92_RS16190	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTZ92_RS16190	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HTZ92_RS16200	COG0004	ammonium transporteR
HTZ92_RS16205	COG0347	Belongs to the P(II) protein family
HTZ92_RS16215	COG0606	chelatase, subunit chli
HTZ92_RS16230	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTZ92_RS16245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HTZ92_RS16260	COG0318	PFAM AMP-dependent synthetase and ligase
HTZ92_RS16270	COG0477	Major facilitator Superfamily
HTZ92_RS16275	COG2860	membrane
HTZ92_RS16285	COG1253	flavin adenine dinucleotide binding
HTZ92_RS16295	COG2814	Major facilitator Superfamily
HTZ92_RS16305	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HTZ92_RS16340	COG0655	NAD(P)H dehydrogenase (quinone) activity
HTZ92_RS16350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HTZ92_RS16420	COG0758	DNA mediated transformation
HTZ92_RS16430	COG0697	spore germination
HTZ92_RS16435	COG1309	transcriptional regulator
HTZ92_RS16450	COG0386	Belongs to the glutathione peroxidase family
HTZ92_RS16515	COG1121	(ABC) transporter
HTZ92_RS16520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HTZ92_RS16525	COG1280	lysine exporter protein (LysE YggA)
HTZ92_RS16530	COG2837	iron assimilation
HTZ92_RS16535	COG0281	malic enzyme
HTZ92_RS16580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HTZ92_RS16580	COG0519	Catalyzes the synthesis of GMP from XMP
HTZ92_RS16585	COG4399	Belongs to the UPF0754 family
HTZ92_RS16590	COG2259	Doxx family
HTZ92_RS16595	COG0586	Pfam SNARE associated Golgi protein
HTZ92_RS16610	COG1192	Involved in chromosome partitioning
HTZ92_RS16620	COG0271	Belongs to the BolA IbaG family
HTZ92_RS16635	COG2267	carboxylic ester hydrolase activity
HTZ92_RS16655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HTZ92_RS16655	COG3321	synthase
HTZ92_RS16655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HTZ92_RS16655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HTZ92_RS16660	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS16670	COG2197	response regulator
HTZ92_RS16680	COG3916	Acyl-homoserine-lactone synthase
HTZ92_RS16685	COG0477	Major facilitator Superfamily
HTZ92_RS16690	COG1024	Enoyl-CoA hydratase
HTZ92_RS16695	COG1024	Enoyl-CoA hydratase
HTZ92_RS16700	COG1960	acyl-CoA dehydrogenase activity
HTZ92_RS16705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTZ92_RS16725	COG1113	amino acid transport
HTZ92_RS16730	COG1113	amino acid transport
HTZ92_RS16735	COG0251	oxidation-reduction process
HTZ92_RS16775	COG0564	pseudouridine synthase activity
HTZ92_RS16860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HTZ92_RS16875	COG1802	Transcriptional regulator
HTZ92_RS16880	COG1448	Aminotransferase
HTZ92_RS16885	COG0277	FAD linked oxidase domain protein
HTZ92_RS16895	COG2186	Transcriptional regulator
HTZ92_RS16905	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTZ92_RS16910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HTZ92_RS16925	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HTZ92_RS16930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HTZ92_RS16955	COG0438	transferase activity, transferring glycosyl groups
HTZ92_RS16985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HTZ92_RS16990	COG1596	polysaccharide export
HTZ92_RS17015	COG0728	peptidoglycan biosynthetic process
HTZ92_RS17020	COG3023	N-Acetylmuramoyl-L-alanine amidase
HTZ92_RS17125	COG2184	nucleotidyltransferase activity
HTZ92_RS17145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HTZ92_RS17180	COG0798	PFAM Bile acid sodium symporter
HTZ92_RS17215	COG4691	Plasmid stability protein
HTZ92_RS17315	COG0546	phosphoglycolate phosphatase activity
HTZ92_RS17320	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS17340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTZ92_RS17345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HTZ92_RS17350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HTZ92_RS17355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HTZ92_RS17360	COG1116	anion transmembrane transporter activity
HTZ92_RS17365	COG1309	transcriptional regulator
HTZ92_RS17370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HTZ92_RS17380	COG0196	riboflavin kinase activity
HTZ92_RS17385	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HTZ92_RS17395	COG1047	Peptidyl-prolyl cis-trans
HTZ92_RS17435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HTZ92_RS17440	COG0657	acetylesterase activity
HTZ92_RS17460	COG0583	DNA-binding transcription factor activity
HTZ92_RS17490	COG2951	lytic endotransglycosylase activity
HTZ92_RS17495	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HTZ92_RS17510	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HTZ92_RS17520	COG0671	phosphoesterase, PA-phosphatase related
HTZ92_RS17525	COG0861	Integral membrane protein TerC family
HTZ92_RS17535	COG0754	glutathionylspermidine amidase activity
HTZ92_RS17545	COG0402	S-adenosylhomocysteine deaminase activity
HTZ92_RS17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HTZ92_RS17565	COG1230	cation diffusion facilitator family transporter
HTZ92_RS17580	COG0706	membrane insertase activity
HTZ92_RS17605	COG0592	DNA-directed DNA polymerase activity
HTZ92_RS17615	COG0187	DNA topoisomerase II activity
HTZ92_RS17625	COG0586	Pfam SNARE associated Golgi protein
HTZ92_RS17630	COG0488	(ABC) transporter
HTZ92_RS17655	COG0596	Alpha beta hydrolase
HTZ92_RS17660	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HTZ92_RS17665	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HTZ92_RS17695	COG0625	glutathione transferase activity
HTZ92_RS17705	COG0733	neurotransmitter:sodium symporter activity
HTZ92_RS17740	COG0583	DNA-binding transcription factor activity
HTZ92_RS17745	COG2233	PERMEase
HTZ92_RS17760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HTZ92_RS17795	COG2814	Major facilitator Superfamily
HTZ92_RS17800	COG0656	L-ascorbic acid biosynthetic process
HTZ92_RS17805	COG0583	DNA-binding transcription factor activity
HTZ92_RS17820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HTZ92_RS17825	COG1064	alcohol dehydrogenase
HTZ92_RS17830	COG2818	Glycosylase
HTZ92_RS17845	COG1194	a g-specific adenine glycosylase
HTZ92_RS17865	COG2983	Belongs to the UPF0260 family
HTZ92_RS17870	COG2133	pyrroloquinoline quinone binding
HTZ92_RS17875	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HTZ92_RS17880	COG2116	formate transmembrane transporter activity
HTZ92_RS17900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HTZ92_RS17905	COG1335	isochorismatase
HTZ92_RS17910	COG0385	Bile acid
HTZ92_RS17920	COG1683	Conserved Protein
HTZ92_RS17940	COG0625	glutathione transferase activity
HTZ92_RS17950	COG1113	amino acid transport
HTZ92_RS17960	COG0523	cobalamin synthesis protein
HTZ92_RS17970	COG2188	Transcriptional regulator
HTZ92_RS18000	COG0010	Belongs to the arginase family
HTZ92_RS18010	COG0546	phosphoglycolate phosphatase activity
HTZ92_RS18015	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HTZ92_RS18020	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HTZ92_RS18030	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HTZ92_RS18035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HTZ92_RS18080	COG0753	catalase activity
HTZ92_RS18130	COG0534	Mate efflux family protein
HTZ92_RS18135	COG0436	Aminotransferase
HTZ92_RS18140	COG2733	membrane
HTZ92_RS18155	COG2918	glutathione biosynthetic process
HTZ92_RS18170	COG3179	chitinase
HTZ92_RS18185	COG3150	esterase
HTZ92_RS18195	COG1028	Short-chain dehydrogenase reductase Sdr
HTZ92_RS18200	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HTZ92_RS18210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HTZ92_RS18220	COG2233	PERMEase
HTZ92_RS18225	COG2351	hydroxyisourate hydrolase activity
HTZ92_RS18260	COG3706	GGDEF domain
HTZ92_RS18275	COG1393	Belongs to the ArsC family
HTZ92_RS18280	COG0708	Exodeoxyribonuclease III
HTZ92_RS18300	COG0189	ligase activity
HTZ92_RS18320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HTZ92_RS18330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HTZ92_RS18345	COG4942	peptidase
HTZ92_RS18355	COG0508	dehydrogenase complex catalyzes the overall conversion of
HTZ92_RS18365	COG2119	membrane
HTZ92_RS18370	COG4774	siderophore transport
HTZ92_RS18375	COG0426	domain, Protein
HTZ92_RS18375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HTZ92_RS18400	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HTZ92_RS18420	COG1902	pentaerythritol trinitrate reductase activity
HTZ92_RS18425	COG1519	Transferase
HTZ92_RS18430	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HTZ92_RS18435	COG0668	transmembrane transport
HTZ92_RS18445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HTZ92_RS18450	COG1335	isochorismatase
HTZ92_RS18455	COG1522	sequence-specific DNA binding
HTZ92_RS18480	COG0784	Response regulator, receiver
HTZ92_RS18480	COG2198	Histidine kinase
HTZ92_RS18480	COG2205	protein histidine kinase activity
HTZ92_RS18485	COG3162	membrane
HTZ92_RS18490	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HTZ92_RS18500	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HTZ92_RS18515	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HTZ92_RS18520	COG1309	transcriptional regulator
HTZ92_RS18540	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HTZ92_RS18540	COG0351	phosphomethylpyrimidine kinase
HTZ92_RS18540	COG0352	thiamine-phosphate diphosphorylase activity
HTZ92_RS18550	COG2814	Major facilitator Superfamily
HTZ92_RS18655	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HTZ92_RS18680	COG1764	response to oxidative stress
HTZ92_RS18685	COG1846	Transcriptional regulator
HTZ92_RS18725	COG3561	AntA/AntB antirepressor