locus-tag	class	description
ABAYE_RS00060	COG0187	DNA topoisomerase II activity
ABAYE_RS00100	COG0592	DNA-directed DNA polymerase activity
ABAYE_RS00560	COG0592	DNA-directed DNA polymerase activity
ABAYE_RS00570	COG0187	DNA topoisomerase II activity
ABAYE_RS00580	COG0586	Pfam SNARE associated Golgi protein
ABAYE_RS00585	COG0488	(ABC) transporter
ABAYE_RS00610	COG0596	Alpha beta hydrolase
ABAYE_RS00615	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ABAYE_RS00620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ABAYE_RS00660	COG0733	neurotransmitter:sodium symporter activity
ABAYE_RS00695	COG0583	DNA-binding transcription factor activity
ABAYE_RS00700	COG2233	PERMEase
ABAYE_RS00715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS00750	COG2814	Major facilitator Superfamily
ABAYE_RS00755	COG0656	L-ascorbic acid biosynthetic process
ABAYE_RS00760	COG0583	DNA-binding transcription factor activity
ABAYE_RS00770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABAYE_RS00775	COG1064	alcohol dehydrogenase
ABAYE_RS00780	COG2818	Glycosylase
ABAYE_RS00795	COG1194	a g-specific adenine glycosylase
ABAYE_RS00815	COG2983	Belongs to the UPF0260 family
ABAYE_RS00820	COG2133	pyrroloquinoline quinone binding
ABAYE_RS00825	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ABAYE_RS00830	COG2116	formate transmembrane transporter activity
ABAYE_RS00850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABAYE_RS00855	COG1335	isochorismatase
ABAYE_RS00860	COG0385	Bile acid
ABAYE_RS00865	COG0534	Mate efflux family protein
ABAYE_RS00870	COG1683	Conserved Protein
ABAYE_RS00890	COG0625	glutathione transferase activity
ABAYE_RS00900	COG1113	amino acid transport
ABAYE_RS00910	COG0523	cobalamin synthesis protein
ABAYE_RS00920	COG2188	Transcriptional regulator
ABAYE_RS00950	COG0010	Belongs to the arginase family
ABAYE_RS00965	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABAYE_RS00990	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ABAYE_RS01000	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ABAYE_RS01005	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ABAYE_RS01090	COG0534	Mate efflux family protein
ABAYE_RS01095	COG0436	Aminotransferase
ABAYE_RS01100	COG2733	membrane
ABAYE_RS01115	COG2918	glutathione biosynthetic process
ABAYE_RS01130	COG3409	Peptidoglycan-binding domain 1 protein
ABAYE_RS01130	COG1388	LysM domain
ABAYE_RS01130	COG5632	N-Acetylmuramoyl-L-alanine amidase
ABAYE_RS01160	COG3150	esterase
ABAYE_RS01170	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ABAYE_RS01180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABAYE_RS01190	COG2233	PERMEase
ABAYE_RS01195	COG2351	hydroxyisourate hydrolase activity
ABAYE_RS01230	COG3706	GGDEF domain
ABAYE_RS01245	COG1393	Belongs to the ArsC family
ABAYE_RS01250	COG0708	Exodeoxyribonuclease III
ABAYE_RS01270	COG0189	ligase activity
ABAYE_RS01290	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ABAYE_RS01300	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ABAYE_RS01315	COG4942	peptidase
ABAYE_RS01325	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABAYE_RS01335	COG2119	membrane
ABAYE_RS01345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS01345	COG0426	domain, Protein
ABAYE_RS01370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ABAYE_RS01390	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS01395	COG1519	Transferase
ABAYE_RS01400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABAYE_RS01405	COG0668	transmembrane transport
ABAYE_RS01415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABAYE_RS01420	COG1335	isochorismatase
ABAYE_RS01425	COG1522	sequence-specific DNA binding
ABAYE_RS01450	COG2205	protein histidine kinase activity
ABAYE_RS01450	COG2198	Histidine kinase
ABAYE_RS01450	COG0784	Response regulator, receiver
ABAYE_RS01455	COG3162	membrane
ABAYE_RS01460	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABAYE_RS01470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABAYE_RS01495	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ABAYE_RS01500	COG1309	transcriptional regulator
ABAYE_RS01520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABAYE_RS01520	COG0351	phosphomethylpyrimidine kinase
ABAYE_RS01520	COG0352	thiamine-phosphate diphosphorylase activity
ABAYE_RS01530	COG2814	Major facilitator Superfamily
ABAYE_RS01545	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABAYE_RS01555	COG1113	amino acid transport
ABAYE_RS01565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABAYE_RS01570	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS01580	COG1335	isochorismatase
ABAYE_RS01610	COG2814	Major facilitator Superfamily
ABAYE_RS01615	COG0583	DNA-binding transcription factor activity
ABAYE_RS01635	COG0667	Aldo Keto reductase
ABAYE_RS01655	COG1733	regulation of RNA biosynthetic process
ABAYE_RS01670	COG1733	regulation of RNA biosynthetic process
ABAYE_RS01675	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABAYE_RS01685	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ABAYE_RS01740	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ABAYE_RS01780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ABAYE_RS01810	COG0427	acetyl-CoA hydrolase
ABAYE_RS01830	COG0659	secondary active sulfate transmembrane transporter activity
ABAYE_RS01835	COG4221	oxidoreductase activity
ABAYE_RS01840	COG2873	o-acetylhomoserine
ABAYE_RS01845	COG0488	(ABC) transporter
ABAYE_RS01910	COG0833	amino acid
ABAYE_RS01955	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ABAYE_RS01960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ABAYE_RS01975	COG2226	methyltransferase
ABAYE_RS02025	COG0070	glutamate synthase
ABAYE_RS02025	COG0069	glutamate synthase activity
ABAYE_RS02025	COG0067	glutamate synthase
ABAYE_RS02030	COG0493	'glutamate synthase
ABAYE_RS02040	COG1704	LemA family
ABAYE_RS02045	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ABAYE_RS02060	COG3307	-O-antigen
ABAYE_RS02080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABAYE_RS02090	COG0194	GDP metabolic process
ABAYE_RS02140	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ABAYE_RS02160	COG5380	lipid catabolic process
ABAYE_RS02165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ABAYE_RS02190	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ABAYE_RS02195	COG0277	FAD linked oxidase domain protein
ABAYE_RS02205	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ABAYE_RS02210	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABAYE_RS02225	COG1289	transmembrane transporter activity
ABAYE_RS02235	COG0628	permease
ABAYE_RS02240	COG1192	Involved in chromosome partitioning
ABAYE_RS02270	COG0833	amino acid
ABAYE_RS02275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABAYE_RS02280	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABAYE_RS02290	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS02330	COG0583	DNA-binding transcription factor activity
ABAYE_RS02380	COG0517	IMP dehydrogenase activity
ABAYE_RS02385	COG1983	PspC domain protein
ABAYE_RS02395	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS02410	COG0408	coproporphyrinogen oxidase activity
ABAYE_RS02430	COG0513	Belongs to the DEAD box helicase family
ABAYE_RS02440	COG1127	ABC transporter
ABAYE_RS02445	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ABAYE_RS02455	COG2854	intermembrane phospholipid transfer
ABAYE_RS02465	COG0598	Magnesium transport protein CorA
ABAYE_RS02475	COG0494	nUDIX hydrolase
ABAYE_RS02480	COG1040	competence protein
ABAYE_RS02485	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ABAYE_RS02505	COG1946	Acyl-CoA thioesterase
ABAYE_RS02510	COG1301	dicarboxylic acid transport
ABAYE_RS02525	COG1959	2 iron, 2 sulfur cluster binding
ABAYE_RS02530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABAYE_RS02530	COG1017	nitric oxide dioxygenase activity
ABAYE_RS02535	COG0433	COG0433 Predicted ATPase
ABAYE_RS02540	COG0626	cystathionine gamma-synthase activity
ABAYE_RS02695	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS02700	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ABAYE_RS02730	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ABAYE_RS02735	COG0339	signal peptide processing
ABAYE_RS02740	COG0557	exoribonuclease II activity
ABAYE_RS02785	COG0179	Fumarylacetoacetate (FAA) hydrolase
ABAYE_RS02790	COG2169	Transcriptional regulator
ABAYE_RS02795	COG0697	spore germination
ABAYE_RS02800	COG1295	ribonuclease BN
ABAYE_RS02835	COG1702	phosphate starvation-inducible protein PhoH
ABAYE_RS02845	COG0741	lytic transglycosylase activity
ABAYE_RS02845	COG0739	heme binding
ABAYE_RS02845	COG1196	nuclear chromosome segregation
ABAYE_RS02875	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ABAYE_RS02880	COG1183	phosphatidylcholine synthase activity
ABAYE_RS02925	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS02930	COG1309	transcriptional regulator
ABAYE_RS02945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABAYE_RS02950	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS02970	COG2969	positive regulation of protein catabolic process
ABAYE_RS02980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ABAYE_RS02995	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ABAYE_RS03000	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ABAYE_RS03020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ABAYE_RS03030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ABAYE_RS03035	COG1408	metallophosphoesterase
ABAYE_RS03045	COG2199	diguanylate cyclase activity
ABAYE_RS03115	COG1607	acyl-coa hydrolase
ABAYE_RS03145	COG2350	Protein conserved in bacteria
ABAYE_RS03155	COG0613	PHP domain protein
ABAYE_RS03160	COG3781	membrane
ABAYE_RS03170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ABAYE_RS03185	COG1862	Preprotein translocase
ABAYE_RS03230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABAYE_RS03235	COG0629	single-stranded DNA binding
ABAYE_RS03275	COG3646	Phage regulatory protein
ABAYE_RS03285	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ABAYE_RS03420	COG4695	Portal protein
ABAYE_RS03425	COG2205	protein histidine kinase activity
ABAYE_RS03430	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ABAYE_RS03450	COG0726	polysaccharide deacetylase
ABAYE_RS03455	COG0463	Glycosyl transferase, family 2
ABAYE_RS03460	COG0438	transferase activity, transferring glycosyl groups
ABAYE_RS03525	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS03530	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS03540	COG2205	protein histidine kinase activity
ABAYE_RS03545	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS03550	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ABAYE_RS03570	COG2096	Adenosyltransferase
ABAYE_RS03620	COG0285	dihydrofolate synthase activity
ABAYE_RS03640	COG0450	alkyl hydroperoxide reductase
ABAYE_RS03655	COG0477	Major facilitator Superfamily
ABAYE_RS03660	COG1272	protein, Hemolysin III
ABAYE_RS03670	COG2153	protein acetylation
ABAYE_RS03690	COG0183	Belongs to the thiolase family
ABAYE_RS03695	COG2207	Transcriptional regulator
ABAYE_RS03715	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABAYE_RS03735	COG0183	Belongs to the thiolase family
ABAYE_RS03745	COG2885	chlorophyll binding
ABAYE_RS03745	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ABAYE_RS03755	COG1690	Belongs to the RtcB family
ABAYE_RS03760	COG0833	amino acid
ABAYE_RS03770	COG2233	PERMEase
ABAYE_RS03775	COG1217	gtp-binding protein TYPA
ABAYE_RS03800	COG2094	Belongs to the DNA glycosylase MPG family
ABAYE_RS03805	COG4772	TonB-dependent receptor
ABAYE_RS03810	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS03825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABAYE_RS03830	COG0354	folic acid binding
ABAYE_RS03840	COG3189	MarR family transcriptional regulator
ABAYE_RS03845	COG2824	Alkylphosphonate utilization operon protein PhnA
ABAYE_RS03850	COG3422	double-strand break repair
ABAYE_RS03890	COG0840	transmembrane signaling receptor activity
ABAYE_RS03905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABAYE_RS03920	COG5510	response to toxic substance
ABAYE_RS03930	COG2832	Protein of unknown function (DUF454)
ABAYE_RS03935	COG1376	ErfK ybiS ycfS ynhG family protein
ABAYE_RS03975	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ABAYE_RS03985	COG1289	transmembrane transporter activity
ABAYE_RS03990	COG2814	Major facilitator Superfamily
ABAYE_RS04005	COG1115	amino acid carrier protein
ABAYE_RS04010	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABAYE_RS04015	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABAYE_RS04020	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ABAYE_RS04045	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABAYE_RS04055	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ABAYE_RS04060	COG1077	Cell shape determining protein MreB Mrl
ABAYE_RS04065	COG1792	Involved in formation and maintenance of cell shape
ABAYE_RS04070	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ABAYE_RS04075	COG0424	maF-like protein
ABAYE_RS04080	COG1530	ribonuclease E activity
ABAYE_RS04090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABAYE_RS04100	COG0560	Phosphoserine phosphatase
ABAYE_RS04110	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABAYE_RS04135	COG2207	Transcriptional regulator
ABAYE_RS04155	COG1113	amino acid transport
ABAYE_RS04160	COG2828	Protein conserved in bacteria
ABAYE_RS04165	COG0142	geranyltranstransferase activity
ABAYE_RS04170	COG2315	Protein conserved in bacteria
ABAYE_RS04185	COG1752	Esterase of the alpha-beta hydrolase superfamily
ABAYE_RS04205	COG2194	sulfuric ester hydrolase activity
ABAYE_RS04210	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS04215	COG0642	Histidine kinase
ABAYE_RS04225	COG0004	ammonium transporteR
ABAYE_RS04230	COG0583	DNA-binding transcription factor activity
ABAYE_RS04250	COG0525	valine-tRNA ligase activity
ABAYE_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS04270	COG0393	Putative heavy-metal-binding
ABAYE_RS04275	COG0393	Putative heavy-metal-binding
ABAYE_RS04280	COG1538	Outer membrane efflux protein
ABAYE_RS04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS04295	COG0671	phosphoesterase, PA-phosphatase related
ABAYE_RS04325	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ABAYE_RS04340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ABAYE_RS04340	COG1648	precorrin-2 dehydrogenase activity
ABAYE_RS04345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ABAYE_RS04350	COG1733	regulation of RNA biosynthetic process
ABAYE_RS04360	COG0531	amino acid
ABAYE_RS04375	COG0321	lipoyl(octanoyl) transferase activity
ABAYE_RS04380	COG2921	Belongs to the UPF0250 family
ABAYE_RS04415	COG2009	succinate dehydrogenase
ABAYE_RS04420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ABAYE_RS04425	COG1053	succinate dehydrogenase
ABAYE_RS04430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ABAYE_RS04445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABAYE_RS04475	COG2354	Protein conserved in bacteria
ABAYE_RS04480	COG2321	neutral zinc metallopeptidase
ABAYE_RS04500	COG2843	Capsule synthesis protein
ABAYE_RS04515	COG0589	response to stress
ABAYE_RS04535	COG0505	Belongs to the CarA family
ABAYE_RS04560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABAYE_RS04565	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ABAYE_RS04615	COG0477	Major facilitator Superfamily
ABAYE_RS04620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ABAYE_RS04635	COG1597	lipid kinase activity
ABAYE_RS04640	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABAYE_RS04665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABAYE_RS04670	COG0584	glycerophosphoryl diester phosphodiesterase
ABAYE_RS04690	COG0741	lytic transglycosylase activity
ABAYE_RS04710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ABAYE_RS04725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABAYE_RS04760	COG0778	Nitroreductase
ABAYE_RS04775	COG1929	Belongs to the glycerate kinase type-1 family
ABAYE_RS04780	COG0243	molybdopterin cofactor binding
ABAYE_RS04785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ABAYE_RS04790	COG3339	Conserved Protein
ABAYE_RS04800	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ABAYE_RS04815	COG1113	amino acid transport
ABAYE_RS04825	COG0019	diaminopimelate decarboxylase activity
ABAYE_RS04835	COG2267	carboxylic ester hydrolase activity
ABAYE_RS04840	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS04845	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ABAYE_RS04875	COG0463	Glycosyl transferase, family 2
ABAYE_RS04895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS04925	COG4591	ABC-type transport system involved in lipoprotein release permease component
ABAYE_RS04930	COG1136	(ABC) transporter
ABAYE_RS04935	COG2333	competence protein COMEC
ABAYE_RS04935	COG0658	competence protein
ABAYE_RS04945	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ABAYE_RS04945	COG0616	signal peptide processing
ABAYE_RS04950	COG0596	Alpha beta hydrolase
ABAYE_RS04955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ABAYE_RS04965	COG0628	permease
ABAYE_RS05000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABAYE_RS05020	COG0823	Involved in the tonB-independent uptake of proteins
ABAYE_RS05040	COG0824	Thioesterase
ABAYE_RS05045	COG1473	amidohydrolase
ABAYE_RS05065	COG0047	phosphoribosylformylglycinamidine synthase activity
ABAYE_RS05065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ABAYE_RS05070	COG2814	Major facilitator Superfamily
ABAYE_RS05085	COG1024	Enoyl-CoA hydratase
ABAYE_RS05090	COG1056	cytidyltransferase-related domain
ABAYE_RS05090	COG1051	belongs to the nudix hydrolase family
ABAYE_RS05100	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ABAYE_RS05115	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ABAYE_RS05130	COG4625	pathogenesis
ABAYE_RS05135	COG0583	DNA-binding transcription factor activity
ABAYE_RS05140	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ABAYE_RS05145	COG4208	sulfate ABC transporter
ABAYE_RS05150	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ABAYE_RS05160	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ABAYE_RS05165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ABAYE_RS05170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ABAYE_RS05190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABAYE_RS05205	COG0681	Belongs to the peptidase S26 family
ABAYE_RS05220	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ABAYE_RS05230	COG1381	Involved in DNA repair and RecF pathway recombination
ABAYE_RS05235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ABAYE_RS05245	COG4221	oxidoreductase activity
ABAYE_RS05270	COG0436	Aminotransferase
ABAYE_RS05290	COG0556	nucleotide-excision repair
ABAYE_RS05345	COG2070	2-Nitropropane dioxygenase
ABAYE_RS05375	COG1215	transferase activity, transferring glycosyl groups
ABAYE_RS05390	COG0415	Belongs to the DNA photolyase family
ABAYE_RS05400	COG1252	NADH dehydrogenase
ABAYE_RS05405	COG1686	Belongs to the peptidase S11 family
ABAYE_RS05420	COG1187	pseudouridine synthase activity
ABAYE_RS05440	COG0477	Major facilitator Superfamily
ABAYE_RS05445	COG0583	DNA-binding transcription factor activity
ABAYE_RS05450	COG1823	symporter activity
ABAYE_RS05460	COG0612	Peptidase, M16
ABAYE_RS05490	COG1203	CRISPR-associated helicase, Cas3
ABAYE_RS05515	COG0352	thiamine-phosphate diphosphorylase activity
ABAYE_RS05550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABAYE_RS05575	COG1309	transcriptional regulator
ABAYE_RS05585	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ABAYE_RS05590	COG0076	glutamate decarboxylase activity
ABAYE_RS05600	COG1522	sequence-specific DNA binding
ABAYE_RS05605	COG3961	Belongs to the TPP enzyme family
ABAYE_RS05610	COG1113	amino acid transport
ABAYE_RS05615	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ABAYE_RS05620	COG0573	inorganic phosphate transmembrane transporter activity
ABAYE_RS05630	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ABAYE_RS05635	COG0616	signal peptide processing
ABAYE_RS05670	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ABAYE_RS05675	COG1686	Belongs to the peptidase S11 family
ABAYE_RS05700	COG0583	DNA-binding transcription factor activity
ABAYE_RS05705	COG1067	ATP-dependent peptidase activity
ABAYE_RS05730	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ABAYE_RS05750	COG1966	Carbon starvation protein
ABAYE_RS05755	COG2879	small protein
ABAYE_RS05765	COG0583	DNA-binding transcription factor activity
ABAYE_RS05770	COG0006	proline dipeptidase activity
ABAYE_RS05775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABAYE_RS05780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABAYE_RS05790	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS05795	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABAYE_RS05800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABAYE_RS05800	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ABAYE_RS05855	COG1741	Belongs to the pirin family
ABAYE_RS05865	COG2964	Protein conserved in bacteria
ABAYE_RS05880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABAYE_RS05885	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ABAYE_RS05890	COG4605	iron ion homeostasis
ABAYE_RS05895	COG4604	ABC transporter, ATP-binding protein
ABAYE_RS05900	COG4607	ABC-type enterochelin transport system periplasmic component
ABAYE_RS05905	COG4774	siderophore transport
ABAYE_RS05915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ABAYE_RS05920	COG1021	2,3-dihydroxybenzoate-AMP ligase
ABAYE_RS05925	COG3433	isochorismatase activity
ABAYE_RS05925	COG1535	isochorismatase
ABAYE_RS05940	COG1132	(ABC) transporter
ABAYE_RS05945	COG1132	(ABC) transporter
ABAYE_RS05950	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ABAYE_RS05960	COG1169	isochorismate synthase
ABAYE_RS05975	COG3739	integral membrane protein
ABAYE_RS06005	COG0302	gtp cyclohydrolase
ABAYE_RS06015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ABAYE_RS06045	COG0308	aminopeptidase N
ABAYE_RS06050	COG0512	Glutamine amidotransferase of anthranilate synthase
ABAYE_RS06065	COG0174	glutamine synthetase
ABAYE_RS06075	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ABAYE_RS06115	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ABAYE_RS06120	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ABAYE_RS06125	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ABAYE_RS06145	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ABAYE_RS06150	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ABAYE_RS06155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ABAYE_RS06170	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS06175	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABAYE_RS06180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABAYE_RS06195	COG2223	nitrite transmembrane transporter activity
ABAYE_RS06205	COG0024	Methionine aminopeptidase
ABAYE_RS06210	COG0052	Belongs to the universal ribosomal protein uS2 family
ABAYE_RS06225	COG2207	Transcriptional regulator
ABAYE_RS06250	COG2951	lytic endotransglycosylase activity
ABAYE_RS06255	COG0772	Belongs to the SEDS family
ABAYE_RS06270	COG0842	Transport permease protein
ABAYE_RS06275	COG1131	(ABC) transporter
ABAYE_RS06315	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS06330	COG4215	(ABC) transporter
ABAYE_RS06335	COG4160	amino acid transport
ABAYE_RS06340	COG4598	ABC transporter
ABAYE_RS06350	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABAYE_RS06355	COG0826	peptidase U32
ABAYE_RS06360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABAYE_RS06375	COG1720	tRNA m6t6A37 methyltransferase activity
ABAYE_RS06395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ABAYE_RS06410	COG0642	Histidine kinase
ABAYE_RS06420	COG0494	nUDIX hydrolase
ABAYE_RS06430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ABAYE_RS06435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ABAYE_RS06440	COG3139	Protein of unknown function (DUF1315)
ABAYE_RS06445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ABAYE_RS06450	COG1301	dicarboxylic acid transport
ABAYE_RS06455	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS06460	COG2819	hydrolase of the alpha beta superfamily
ABAYE_RS06470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ABAYE_RS06480	COG2195	Cleaves the N-terminal amino acid of tripeptides
ABAYE_RS06485	COG1234	tRNA 3'-trailer cleavage
ABAYE_RS06510	COG2363	Small membrane protein
ABAYE_RS06530	COG0513	Belongs to the DEAD box helicase family
ABAYE_RS06540	COG0778	Nitroreductase
ABAYE_RS06635	COG1484	DNA-dependent DNA replication
ABAYE_RS06815	COG1286	toxin biosynthetic process
ABAYE_RS06840	COG4783	chaperone-mediated protein folding
ABAYE_RS06845	COG1610	YqeY-like protein
ABAYE_RS06945	COG3111	PFAM Bacterial OB fold (BOF) protein
ABAYE_RS06970	COG3243	poly(R)-hydroxyalkanoic acid synthase
ABAYE_RS06975	COG0786	glutamate:sodium symporter activity
ABAYE_RS06985	COG0583	DNA-binding transcription factor activity
ABAYE_RS06995	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS07010	COG2186	Transcriptional regulator
ABAYE_RS07070	COG0477	Major facilitator Superfamily
ABAYE_RS07095	COG2995	paraquat-inducible protein a
ABAYE_RS07100	COG3008	intermembrane lipid transfer
ABAYE_RS07100	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ABAYE_RS07110	COG2351	hydroxyisourate hydrolase activity
ABAYE_RS07150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABAYE_RS07160	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ABAYE_RS07165	COG0642	Histidine kinase
ABAYE_RS07170	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS07190	COG1794	racemase activity, acting on amino acids and derivatives
ABAYE_RS07220	COG1301	dicarboxylic acid transport
ABAYE_RS07230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABAYE_RS07235	COG2011	ABC-type metal ion transport system permease component
ABAYE_RS07240	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABAYE_RS07245	COG1464	Belongs to the NlpA lipoprotein family
ABAYE_RS07250	COG0151	Belongs to the GarS family
ABAYE_RS07255	COG0138	bifunctional purine biosynthesis protein purh
ABAYE_RS07260	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ABAYE_RS07290	COG2308	Evidence 4 Homologs of previously reported genes of
ABAYE_RS07300	COG1305	Transglutaminase-like
ABAYE_RS07310	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ABAYE_RS07315	COG0305	Participates in initiation and elongation during chromosome replication
ABAYE_RS07340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ABAYE_RS07350	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ABAYE_RS07355	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ABAYE_RS07380	COG1649	PFAM Uncharacterised BCR, COG1649
ABAYE_RS07380	COG0726	polysaccharide deacetylase
ABAYE_RS07385	COG1215	transferase activity, transferring glycosyl groups
ABAYE_RS07390	COG3658	cytochrome
ABAYE_RS07400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABAYE_RS07420	COG0583	DNA-binding transcription factor activity
ABAYE_RS07440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABAYE_RS07445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABAYE_RS07460	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS07465	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABAYE_RS07470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS07495	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ABAYE_RS07500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ABAYE_RS07510	COG2205	protein histidine kinase activity
ABAYE_RS07515	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS07520	COG0174	glutamine synthetase
ABAYE_RS07540	COG0729	surface antigen
ABAYE_RS07565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABAYE_RS07570	COG2814	Major facilitator Superfamily
ABAYE_RS07585	COG0583	DNA-binding transcription factor activity
ABAYE_RS07600	COG1187	pseudouridine synthase activity
ABAYE_RS07620	COG0802	atpase or kinase
ABAYE_RS07625	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ABAYE_RS07635	COG1923	regulation of RNA biosynthetic process
ABAYE_RS07640	COG0697	spore germination
ABAYE_RS07660	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABAYE_RS07665	COG0519	Catalyzes the synthesis of GMP from XMP
ABAYE_RS07665	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABAYE_RS07670	COG4302	ethanolamine ammonia-lyase activity
ABAYE_RS07675	COG4303	Ethanolamine ammonia lyase large subunit
ABAYE_RS07680	COG0531	amino acid
ABAYE_RS07700	COG1454	alcohol dehydrogenase
ABAYE_RS07705	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABAYE_RS07730	COG0308	aminopeptidase N
ABAYE_RS07770	COG1605	Chorismate mutase
ABAYE_RS07790	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ABAYE_RS07805	COG1309	transcriptional regulator
ABAYE_RS07815	COG0668	transmembrane transport
ABAYE_RS07845	COG4773	Receptor
ABAYE_RS07865	COG0488	(ABC) transporter
ABAYE_RS07870	COG0589	response to stress
ABAYE_RS07890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ABAYE_RS07900	COG3135	benzoate transporter
ABAYE_RS07905	COG1522	sequence-specific DNA binding
ABAYE_RS07915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ABAYE_RS07920	COG0583	DNA-binding transcription factor activity
ABAYE_RS07930	COG0183	Belongs to the thiolase family
ABAYE_RS07940	COG2030	dehydratase
ABAYE_RS07945	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABAYE_RS07960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ABAYE_RS07970	COG0824	Thioesterase
ABAYE_RS07975	COG1454	alcohol dehydrogenase
ABAYE_RS07985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ABAYE_RS08005	COG0069	glutamate synthase activity
ABAYE_RS08025	COG2814	Major facilitator Superfamily
ABAYE_RS08040	COG0511	ligase activity, forming carbon-carbon bonds
ABAYE_RS08055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABAYE_RS08055	COG1116	anion transmembrane transporter activity
ABAYE_RS08060	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS08070	COG2146	nitrite reductase [NAD(P)H] activity
ABAYE_RS08070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABAYE_RS08075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABAYE_RS08080	COG0243	molybdopterin cofactor binding
ABAYE_RS08090	COG0243	molybdopterin cofactor binding
ABAYE_RS08095	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ABAYE_RS08110	COG0521	Mo-molybdopterin cofactor biosynthetic process
ABAYE_RS08110	COG0315	cyclic pyranopterin monophosphate synthase activity
ABAYE_RS08115	COG0303	'Molybdopterin
ABAYE_RS08130	COG0697	spore germination
ABAYE_RS08150	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ABAYE_RS08155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ABAYE_RS08210	COG2204	response regulator
ABAYE_RS08215	COG3852	Histidine kinase
ABAYE_RS08235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ABAYE_RS08240	COG0575	Belongs to the CDS family
ABAYE_RS08275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABAYE_RS08285	COG2137	regulation of response to DNA damage stimulus
ABAYE_RS08295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ABAYE_RS08300	COG1011	Hydrolase
ABAYE_RS08325	COG1522	sequence-specific DNA binding
ABAYE_RS08335	COG1113	amino acid transport
ABAYE_RS08350	COG0659	secondary active sulfate transmembrane transporter activity
ABAYE_RS08355	COG2135	peptidase activity
ABAYE_RS08370	COG3300	MHYT domain
ABAYE_RS08370	COG5001	Diguanylate cyclase
ABAYE_RS08390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABAYE_RS08390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ABAYE_RS08390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ABAYE_RS08395	COG1105	Belongs to the carbohydrate kinase PfkB family
ABAYE_RS08400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABAYE_RS08400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ABAYE_RS08430	COG0024	Methionine aminopeptidase
ABAYE_RS08435	COG0583	DNA-binding transcription factor activity
ABAYE_RS08445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ABAYE_RS08450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ABAYE_RS08455	COG0517	IMP dehydrogenase activity
ABAYE_RS08455	COG0516	GMP reductase activity
ABAYE_RS08480	COG0552	protein localization to endoplasmic reticulum
ABAYE_RS08490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ABAYE_RS08500	COG4890	Cyd operon protein YbgT
ABAYE_RS08505	COG1294	oxidase, subunit
ABAYE_RS08530	COG1585	Membrane protein implicated in regulation of membrane protease activity
ABAYE_RS08540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ABAYE_RS08545	COG4774	siderophore transport
ABAYE_RS08560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ABAYE_RS08565	COG0569	domain protein
ABAYE_RS08570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ABAYE_RS08600	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ABAYE_RS08605	COG0542	response to heat
ABAYE_RS08630	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABAYE_RS08630	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS08675	COG2323	membrane
ABAYE_RS08680	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ABAYE_RS08690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABAYE_RS08695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABAYE_RS08700	COG0183	Belongs to the thiolase family
ABAYE_RS08705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ABAYE_RS08710	COG0596	Alpha beta hydrolase
ABAYE_RS08715	COG2271	Major facilitator Superfamily
ABAYE_RS08720	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABAYE_RS08725	COG3485	protocatechuate 3,4-dioxygenase
ABAYE_RS08730	COG3485	protocatechuate 3,4-dioxygenase
ABAYE_RS08735	COG0710	3-dehydroquinate dehydratase activity
ABAYE_RS08740	COG3420	alginic acid biosynthetic process
ABAYE_RS08745	COG3659	wide pore channel activity
ABAYE_RS08750	COG4993	Dehydrogenase
ABAYE_RS08760	COG2391	methyltransferase activity
ABAYE_RS08775	COG1414	Transcriptional regulator
ABAYE_RS08780	COG0583	DNA-binding transcription factor activity
ABAYE_RS08785	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS08810	COG2814	Major facilitator Superfamily
ABAYE_RS08820	COG0154	amidase activity
ABAYE_RS08840	COG4638	Rieske (2fe-2S)
ABAYE_RS08850	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS08860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS08870	COG3733	amine oxidase
ABAYE_RS08880	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS08890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABAYE_RS08895	COG0183	Belongs to the thiolase family
ABAYE_RS08900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABAYE_RS08905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABAYE_RS08915	COG4829	muconolactone delta-isomerase
ABAYE_RS08920	COG4948	Mandelate Racemase Muconate Lactonizing
ABAYE_RS08925	COG0583	DNA-binding transcription factor activity
ABAYE_RS08935	COG2186	Transcriptional regulator
ABAYE_RS08955	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS08970	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABAYE_RS08970	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS09010	COG1309	transcriptional regulator
ABAYE_RS09025	COG4689	acetoacetate decarboxylase
ABAYE_RS09035	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS09055	COG1335	isochorismatase
ABAYE_RS09060	COG0583	DNA-binding transcription factor activity
ABAYE_RS09070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABAYE_RS09070	COG0475	glutathione-regulated potassium exporter activity
ABAYE_RS09080	COG1473	amidohydrolase
ABAYE_RS09165	COG2188	Transcriptional regulator
ABAYE_RS09180	COG0583	DNA-binding transcription factor activity
ABAYE_RS09195	COG1566	PFAM secretion protein HlyD family protein
ABAYE_RS09210	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS09215	COG0129	dihydroxy-acid dehydratase activity
ABAYE_RS09225	COG0583	DNA-binding transcription factor activity
ABAYE_RS09230	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ABAYE_RS09240	COG2084	Dehydrogenase
ABAYE_RS09245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABAYE_RS09305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ABAYE_RS09320	COG0556	nucleotide-excision repair
ABAYE_RS09350	COG1073	alpha beta
ABAYE_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS09375	COG2207	Transcriptional regulator
ABAYE_RS09385	COG2205	protein histidine kinase activity
ABAYE_RS09390	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS09395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS09400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABAYE_RS09405	COG1538	Outer membrane efflux protein
ABAYE_RS09415	COG2072	flavoprotein involved in K transport
ABAYE_RS09425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABAYE_RS09570	COG3539	Fimbrial protein
ABAYE_RS09595	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ABAYE_RS09605	COG0753	catalase activity
ABAYE_RS09705	COG3433	isochorismatase activity
ABAYE_RS09705	COG1535	isochorismatase
ABAYE_RS09715	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ABAYE_RS09720	COG4149	molybdate abc transporter
ABAYE_RS09725	COG0725	ABC transporter, periplasmic molybdate-binding protein
ABAYE_RS09735	COG4638	Rieske (2fe-2S)
ABAYE_RS09740	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ABAYE_RS09745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABAYE_RS09745	COG0543	2 iron, 2 sulfur cluster binding
ABAYE_RS09760	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS09785	COG2207	Transcriptional regulator
ABAYE_RS09790	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS09795	COG2610	gluconate transmembrane transporter activity
ABAYE_RS09805	COG0583	DNA-binding transcription factor activity
ABAYE_RS09820	COG2031	fatty acid transporter
ABAYE_RS09825	COG0183	Belongs to the thiolase family
ABAYE_RS09830	COG0583	DNA-binding transcription factor activity
ABAYE_RS09835	COG0583	DNA-binding transcription factor activity
ABAYE_RS09850	COG1027	Aspartate ammonia-lyase
ABAYE_RS09860	COG0477	Major facilitator Superfamily
ABAYE_RS09880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABAYE_RS09885	COG4521	taurine ABC transporter
ABAYE_RS09900	COG2188	Transcriptional regulator
ABAYE_RS09910	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ABAYE_RS09915	COG1733	regulation of RNA biosynthetic process
ABAYE_RS09920	COG2207	Transcriptional regulator
ABAYE_RS09920	COG3708	Transcriptional regulator
ABAYE_RS09935	COG0730	response to heat
ABAYE_RS09945	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABAYE_RS09945	COG3453	Protein conserved in bacteria
ABAYE_RS09955	COG3781	membrane
ABAYE_RS09960	COG1063	alcohol dehydrogenase
ABAYE_RS09970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ABAYE_RS09975	COG0508	dehydrogenase complex catalyzes the overall conversion of
ABAYE_RS09980	COG0022	dehydrogenase e1 component
ABAYE_RS09985	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ABAYE_RS09990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ABAYE_RS10005	COG3706	GGDEF domain
ABAYE_RS10020	COG0133	tryptophan synthase activity
ABAYE_RS10030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ABAYE_RS10065	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ABAYE_RS10090	COG2226	methyltransferase
ABAYE_RS10145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ABAYE_RS10150	COG4773	Receptor
ABAYE_RS10170	COG0730	response to heat
ABAYE_RS10175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ABAYE_RS10190	COG0406	alpha-ribazole phosphatase activity
ABAYE_RS10195	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ABAYE_RS10210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABAYE_RS10240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABAYE_RS10250	COG4264	IucA IucC family
ABAYE_RS10255	COG4264	IucA IucC family
ABAYE_RS10260	COG2814	Major facilitator Superfamily
ABAYE_RS10275	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ABAYE_RS10290	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS10295	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS10300	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ABAYE_RS10305	COG2207	Transcriptional regulator
ABAYE_RS10310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABAYE_RS10315	COG0776	regulation of translation
ABAYE_RS10340	COG0822	iron-sulfur transferase activity
ABAYE_RS10345	COG0316	Belongs to the HesB IscA family
ABAYE_RS10375	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ABAYE_RS10395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ABAYE_RS10400	COG0702	epimerase
ABAYE_RS10435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ABAYE_RS10445	COG0339	signal peptide processing
ABAYE_RS10465	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ABAYE_RS10490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ABAYE_RS10495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ABAYE_RS10525	COG0776	regulation of translation
ABAYE_RS10590	COG0084	hydrolase, TatD family'
ABAYE_RS10610	COG1663	tetraacyldisaccharide 4'-kinase activity
ABAYE_RS10615	COG1132	(ABC) transporter
ABAYE_RS10625	COG0811	peptide transport
ABAYE_RS10630	COG1475	DNA binding
ABAYE_RS10635	COG1192	Involved in chromosome partitioning
ABAYE_RS10645	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ABAYE_RS10660	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ABAYE_RS10665	COG0191	fructose-bisphosphate aldolase activity
ABAYE_RS10685	COG0424	maF-like protein
ABAYE_RS10690	COG2850	peptidyl-arginine hydroxylation
ABAYE_RS10700	COG0640	Transcriptional regulator
ABAYE_RS10710	COG3619	membrane
ABAYE_RS10715	COG3122	Protein conserved in bacteria
ABAYE_RS10720	COG1132	(ABC) transporter
ABAYE_RS10740	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ABAYE_RS10745	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ABAYE_RS10755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABAYE_RS10755	COG0506	proline dehydrogenase activity
ABAYE_RS10755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ABAYE_RS10760	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ABAYE_RS10775	COG3698	Phosphodiester glycosidase
ABAYE_RS10785	COG2353	YceI-like domain
ABAYE_RS10795	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ABAYE_RS10840	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ABAYE_RS10840	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ABAYE_RS10865	COG3539	Fimbrial protein
ABAYE_RS10870	COG3121	Chaperone
ABAYE_RS10905	COG0697	spore germination
ABAYE_RS10915	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABAYE_RS10925	COG0583	DNA-binding transcription factor activity
ABAYE_RS10945	COG1309	transcriptional regulator
ABAYE_RS10960	COG1522	sequence-specific DNA binding
ABAYE_RS10970	COG1126	abc transporter atp-binding protein
ABAYE_RS10975	COG0765	amino acid transport
ABAYE_RS10980	COG0765	amino acid transport
ABAYE_RS11010	COG1464	Belongs to the NlpA lipoprotein family
ABAYE_RS11020	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ABAYE_RS11025	COG2011	ABC-type metal ion transport system permease component
ABAYE_RS11030	COG0012	GTP binding
ABAYE_RS11055	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ABAYE_RS11095	COG0386	Belongs to the glutathione peroxidase family
ABAYE_RS11105	COG0436	Aminotransferase
ABAYE_RS11110	COG1301	dicarboxylic acid transport
ABAYE_RS11145	COG3634	alkyl hydroperoxide reductase activity
ABAYE_RS11160	COG0583	DNA-binding transcription factor activity
ABAYE_RS11165	COG0798	PFAM Bile acid sodium symporter
ABAYE_RS11170	COG0640	Transcriptional regulator
ABAYE_RS11185	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ABAYE_RS11195	COG0583	DNA-binding transcription factor activity
ABAYE_RS11205	COG1953	Uracil, thiamine, allantoin
ABAYE_RS11215	COG2175	clavaminate synthase activity
ABAYE_RS11220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABAYE_RS11225	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ABAYE_RS11230	COG4521	taurine ABC transporter
ABAYE_RS11240	COG0477	Major facilitator Superfamily
ABAYE_RS11260	COG1271	oxidase subunit
ABAYE_RS11265	COG1294	oxidase, subunit
ABAYE_RS11275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABAYE_RS11295	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ABAYE_RS11315	COG3052	prosthetic group binding
ABAYE_RS11320	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ABAYE_RS11330	COG2814	Major facilitator Superfamily
ABAYE_RS11350	COG1346	cytolysis
ABAYE_RS11360	COG0583	DNA-binding transcription factor activity
ABAYE_RS11365	COG0625	glutathione transferase activity
ABAYE_RS11370	COG0625	glutathione transferase activity
ABAYE_RS11375	COG0583	DNA-binding transcription factor activity
ABAYE_RS11390	COG1045	serine acetyltransferase
ABAYE_RS11395	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ABAYE_RS11400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ABAYE_RS11405	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS11415	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABAYE_RS11420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABAYE_RS11425	COG1126	abc transporter atp-binding protein
ABAYE_RS11430	COG0765	amino acid transport
ABAYE_RS11435	COG0765	amino acid transport
ABAYE_RS11450	COG0784	Response regulator, receiver
ABAYE_RS11450	COG2205	protein histidine kinase activity
ABAYE_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS11540	COG0583	DNA-binding transcription factor activity
ABAYE_RS11560	COG0318	PFAM AMP-dependent synthetase and ligase
ABAYE_RS11565	COG1309	transcriptional regulator
ABAYE_RS11570	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS11575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ABAYE_RS11580	COG1024	Enoyl-CoA hydratase
ABAYE_RS11585	COG4770	biotin carboxylase activity
ABAYE_RS11595	COG0583	DNA-binding transcription factor activity
ABAYE_RS11610	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS11620	COG2814	Major facilitator Superfamily
ABAYE_RS11630	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ABAYE_RS11635	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ABAYE_RS11640	COG2814	Major facilitator Superfamily
ABAYE_RS11645	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS11650	COG1024	Enoyl-CoA hydratase
ABAYE_RS11655	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS11660	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABAYE_RS11665	COG0183	Belongs to the thiolase family
ABAYE_RS11675	COG2814	Major facilitator Superfamily
ABAYE_RS11685	COG1024	Enoyl-CoA hydratase
ABAYE_RS11695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABAYE_RS11700	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS11705	COG2814	Major facilitator Superfamily
ABAYE_RS11710	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ABAYE_RS11715	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ABAYE_RS11730	COG3842	ATPase activity
ABAYE_RS11735	COG1840	ABC-type Fe3 transport system, periplasmic component
ABAYE_RS11745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABAYE_RS11750	COG1414	Transcriptional regulator
ABAYE_RS11760	COG0583	DNA-binding transcription factor activity
ABAYE_RS11765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ABAYE_RS11770	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS11780	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ABAYE_RS11785	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS11790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABAYE_RS11795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS11800	COG2267	carboxylic ester hydrolase activity
ABAYE_RS11820	COG3038	cytochrome b561
ABAYE_RS11825	COG0753	catalase activity
ABAYE_RS11830	COG2271	Major facilitator Superfamily
ABAYE_RS11835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABAYE_RS11840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABAYE_RS11875	COG1278	Cold shock
ABAYE_RS11905	COG0210	DNA helicase
ABAYE_RS11910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ABAYE_RS11915	COG2050	protein possibly involved in aromatic compounds catabolism
ABAYE_RS11925	COG3327	negative regulation of DNA-templated transcription, initiation
ABAYE_RS11930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ABAYE_RS11935	COG0183	Belongs to the thiolase family
ABAYE_RS11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABAYE_RS11945	COG1024	Enoyl-CoA hydratase
ABAYE_RS11950	COG1024	Enoyl-CoA hydratase
ABAYE_RS11955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABAYE_RS11960	COG2151	metal-sulfur cluster biosynthetic enzyme
ABAYE_RS11965	COG3396	Phenylacetate-CoA oxygenase
ABAYE_RS11970	COG3460	Phenylacetate-CoA oxygenase
ABAYE_RS11975	COG3396	Phenylacetate-CoA oxygenase
ABAYE_RS11980	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS11980	COG2030	dehydratase
ABAYE_RS11985	COG1760	l-serine dehydratase
ABAYE_RS11990	COG0531	amino acid
ABAYE_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS12020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ABAYE_RS12040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABAYE_RS12050	COG0789	Transcriptional regulator
ABAYE_RS12060	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ABAYE_RS12075	COG2807	transmembrane transport
ABAYE_RS12080	COG0590	tRNA wobble adenosine to inosine editing
ABAYE_RS12195	COG1116	anion transmembrane transporter activity
ABAYE_RS12200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ABAYE_RS12210	COG0864	Transcriptional regulator
ABAYE_RS12220	COG1733	regulation of RNA biosynthetic process
ABAYE_RS12225	COG2249	NAD(P)H dehydrogenase (quinone) activity
ABAYE_RS12245	COG1063	alcohol dehydrogenase
ABAYE_RS12255	COG1309	transcriptional regulator
ABAYE_RS12280	COG0038	chloride channel
ABAYE_RS12285	COG4770	biotin carboxylase activity
ABAYE_RS12305	COG1914	H( )-stimulated, divalent metal cation uptake system
ABAYE_RS12310	COG0583	DNA-binding transcription factor activity
ABAYE_RS12330	COG3209	COG3209 Rhs family protein
ABAYE_RS12385	COG1250	3-hydroxyacyl-CoA dehydrogenase
ABAYE_RS12405	COG2814	Major facilitator Superfamily
ABAYE_RS12415	COG1560	Kdo2-lipid A biosynthetic process
ABAYE_RS12425	COG5006	permease, DMT superfamily
ABAYE_RS12440	COG1522	sequence-specific DNA binding
ABAYE_RS12455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ABAYE_RS12465	COG4122	O-methyltransferase activity
ABAYE_RS12495	COG1538	Outer membrane efflux protein
ABAYE_RS12500	COG1137	ATPase activity
ABAYE_RS12505	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ABAYE_RS12515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ABAYE_RS12575	COG5434	Belongs to the glycosyl hydrolase 28 family
ABAYE_RS12595	COG3566	protein conserved in bacteria
ABAYE_RS12615	COG3567	Phage-associated protein, HI1409 family
ABAYE_RS12620	COG5410	chromosome segregation
ABAYE_RS12690	COG2814	Major facilitator Superfamily
ABAYE_RS12720	COG1278	Cold shock
ABAYE_RS12725	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS12760	COG1570	exodeoxyribonuclease VII activity
ABAYE_RS12810	COG0583	DNA-binding transcription factor activity
ABAYE_RS12815	COG4638	Rieske (2fe-2S)
ABAYE_RS12820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ABAYE_RS12825	COG0543	2 iron, 2 sulfur cluster binding
ABAYE_RS12825	COG0633	Ferredoxin
ABAYE_RS12830	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS12835	COG3135	benzoate transporter
ABAYE_RS12840	COG2814	Major facilitator Superfamily
ABAYE_RS12855	COG1643	Atp-dependent helicase
ABAYE_RS12860	COG0450	alkyl hydroperoxide reductase
ABAYE_RS12870	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ABAYE_RS12880	COG3634	alkyl hydroperoxide reductase activity
ABAYE_RS12900	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ABAYE_RS12905	COG0625	glutathione transferase activity
ABAYE_RS12915	COG2885	chlorophyll binding
ABAYE_RS12950	COG0542	response to heat
ABAYE_RS12965	COG1765	OsmC-like protein
ABAYE_RS12975	COG0667	Aldo Keto reductase
ABAYE_RS12990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ABAYE_RS13000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ABAYE_RS13010	COG0527	aspartate kinase activity
ABAYE_RS13020	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ABAYE_RS13030	COG3038	cytochrome b561
ABAYE_RS13035	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ABAYE_RS13040	COG2252	PERMEase
ABAYE_RS13050	COG2072	flavoprotein involved in K transport
ABAYE_RS13065	COG1741	Belongs to the pirin family
ABAYE_RS13070	COG1309	transcriptional regulator
ABAYE_RS13080	COG0300	oxidoreductase activity
ABAYE_RS13085	COG2072	flavoprotein involved in K transport
ABAYE_RS13090	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ABAYE_RS13135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ABAYE_RS13150	COG2814	Major facilitator Superfamily
ABAYE_RS13155	COG1024	Enoyl-CoA hydratase
ABAYE_RS13160	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS13170	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS13215	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABAYE_RS13215	COG1902	pentaerythritol trinitrate reductase activity
ABAYE_RS13225	COG2203	Gaf domain
ABAYE_RS13225	COG5001	Diguanylate cyclase
ABAYE_RS13225	COG3706	GGDEF domain
ABAYE_RS13225	COG4251	negative regulation of phosphorylation
ABAYE_RS13250	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABAYE_RS13310	COG4172	Belongs to the ABC transporter superfamily
ABAYE_RS13315	COG4239	(ABC) transporter, permease
ABAYE_RS13320	COG4174	ABC transporter (Permease)
ABAYE_RS13330	COG1388	LysM domain
ABAYE_RS13330	COG0741	lytic transglycosylase activity
ABAYE_RS13330	COG1388	LysM domain
ABAYE_RS13330	COG0741	lytic transglycosylase activity
ABAYE_RS13335	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ABAYE_RS13375	COG0583	DNA-binding transcription factor activity
ABAYE_RS13380	COG1279	arginine transmembrane transporter activity
ABAYE_RS13400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABAYE_RS13405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABAYE_RS13410	COG0006	proline dipeptidase activity
ABAYE_RS13440	COG1278	Cold shock
ABAYE_RS13495	COG0739	heme binding
ABAYE_RS13785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ABAYE_RS13800	COG3384	dioxygenase
ABAYE_RS13810	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ABAYE_RS13815	COG2878	Part of a membrane complex involved in electron transport
ABAYE_RS13820	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ABAYE_RS13840	COG0768	penicillin binding
ABAYE_RS13845	COG0742	ribosomal rna small subunit methyltransferase
ABAYE_RS13860	COG0830	nickel cation binding
ABAYE_RS13870	COG0804	urea catabolic process
ABAYE_RS13910	COG1253	flavin adenine dinucleotide binding
ABAYE_RS13915	COG2851	Citrate transporter
ABAYE_RS13960	COG1773	rubredoxin
ABAYE_RS13965	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ABAYE_RS13975	COG0583	DNA-binding transcription factor activity
ABAYE_RS14000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ABAYE_RS14005	COG4181	ATPase activity
ABAYE_RS14050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ABAYE_RS14070	COG0306	phosphate transporter
ABAYE_RS14080	COG3958	Transketolase
ABAYE_RS14085	COG3959	Transketolase, thiamine diphosphate binding domain
ABAYE_RS14090	COG2271	Major facilitator Superfamily
ABAYE_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS14100	COG0583	DNA-binding transcription factor activity
ABAYE_RS14115	COG2223	nitrite transmembrane transporter activity
ABAYE_RS14120	COG2207	Transcriptional regulator
ABAYE_RS14125	COG2066	Belongs to the glutaminase family
ABAYE_RS14130	COG0242	peptide deformylase activity
ABAYE_RS14135	COG0477	Major facilitator Superfamily
ABAYE_RS14145	COG0028	Belongs to the TPP enzyme family
ABAYE_RS14160	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS14165	COG2267	carboxylic ester hydrolase activity
ABAYE_RS14175	COG2271	Major facilitator Superfamily
ABAYE_RS14180	COG0446	pyridine nucleotide-disulphide oxidoreductase
ABAYE_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS14210	COG1414	Transcriptional regulator
ABAYE_RS14225	COG1024	Enoyl-CoA hydratase
ABAYE_RS14235	COG1215	transferase activity, transferring glycosyl groups
ABAYE_RS14240	COG1649	PFAM Uncharacterised BCR, COG1649
ABAYE_RS14240	COG0726	polysaccharide deacetylase
ABAYE_RS14250	COG4681	YaeQ
ABAYE_RS14260	COG0523	cobalamin synthesis protein
ABAYE_RS14270	COG1607	acyl-coa hydrolase
ABAYE_RS14280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABAYE_RS14285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ABAYE_RS14290	COG1309	transcriptional regulator
ABAYE_RS14315	COG2040	homocysteine
ABAYE_RS14320	COG0531	amino acid
ABAYE_RS14345	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABAYE_RS14350	COG0477	Major facilitator Superfamily
ABAYE_RS14370	COG0084	hydrolase, TatD family'
ABAYE_RS14455	COG0582	viral genome integration into host DNA
ABAYE_RS14460	COG0405	Gamma-glutamyltransferase
ABAYE_RS14465	COG2814	Major facilitator Superfamily
ABAYE_RS14475	COG2050	protein possibly involved in aromatic compounds catabolism
ABAYE_RS14490	COG1090	epimerase
ABAYE_RS14510	COG0420	3'-5' exonuclease activity
ABAYE_RS14535	COG0735	belongs to the Fur family
ABAYE_RS14540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ABAYE_RS14560	COG0121	glutamine amidotransferase
ABAYE_RS14575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABAYE_RS14585	COG0210	DNA helicase
ABAYE_RS14590	COG2885	chlorophyll binding
ABAYE_RS14595	COG0204	Acyl-transferase
ABAYE_RS14610	COG2894	cell division
ABAYE_RS14625	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS14630	COG1674	ftsk spoiiie
ABAYE_RS14630	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ABAYE_RS14635	COG0492	ferredoxin-NADP+ reductase activity
ABAYE_RS14640	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ABAYE_RS14650	COG0456	acetyltransferase
ABAYE_RS14695	COG1981	membrane
ABAYE_RS14710	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ABAYE_RS14710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABAYE_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS14745	COG4638	Rieske (2fe-2S)
ABAYE_RS14750	COG0657	acetylesterase activity
ABAYE_RS14760	COG0473	3-isopropylmalate dehydrogenase activity
ABAYE_RS14765	COG0583	DNA-binding transcription factor activity
ABAYE_RS14780	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABAYE_RS14805	COG0564	pseudouridine synthase activity
ABAYE_RS14815	COG0358	DNA primase activity
ABAYE_RS14830	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ABAYE_RS14860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ABAYE_RS14890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ABAYE_RS14900	COG0351	phosphomethylpyrimidine kinase
ABAYE_RS14900	COG0352	thiamine-phosphate diphosphorylase activity
ABAYE_RS14900	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ABAYE_RS14905	COG1652	LysM domain
ABAYE_RS14930	COG1399	metal-binding, possibly nucleic acid-binding protein
ABAYE_RS14935	COG3101	peptidyl-lysine hydroxylation
ABAYE_RS14940	COG0009	L-threonylcarbamoyladenylate synthase
ABAYE_RS14945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ABAYE_RS14950	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ABAYE_RS14965	COG4106	trans-aconitate 2-methyltransferase activity
ABAYE_RS14980	COG0596	Alpha beta hydrolase
ABAYE_RS14980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABAYE_RS14980	COG2226	methyltransferase
ABAYE_RS14985	COG1877	trehalose-phosphatase activity
ABAYE_RS14990	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ABAYE_RS14995	COG2223	nitrite transmembrane transporter activity
ABAYE_RS15015	COG1196	nuclear chromosome segregation
ABAYE_RS15025	COG0730	response to heat
ABAYE_RS15040	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ABAYE_RS15050	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABAYE_RS15100	COG0489	protein tyrosine kinase activity
ABAYE_RS15110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABAYE_RS15110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABAYE_RS15140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ABAYE_RS15145	COG2081	HI0933 family
ABAYE_RS15155	COG0668	transmembrane transport
ABAYE_RS15175	COG0583	DNA-binding transcription factor activity
ABAYE_RS15200	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ABAYE_RS15205	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABAYE_RS15235	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ABAYE_RS15275	COG0745	RESPONSE REGULATOR receiver
ABAYE_RS15295	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ABAYE_RS15305	COG0384	phenazine biosynthesis protein PhzF
ABAYE_RS15335	COG1309	transcriptional regulator
ABAYE_RS15340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ABAYE_RS15355	COG0583	DNA-binding transcription factor activity
ABAYE_RS15385	COG0583	DNA-binding transcription factor activity
ABAYE_RS15400	COG0583	DNA-binding transcription factor activity
ABAYE_RS15405	COG1053	succinate dehydrogenase
ABAYE_RS15415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ABAYE_RS15420	COG2814	Major facilitator Superfamily
ABAYE_RS15425	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS15430	COG0583	DNA-binding transcription factor activity
ABAYE_RS15435	COG1063	alcohol dehydrogenase
ABAYE_RS15465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ABAYE_RS15470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ABAYE_RS15475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABAYE_RS15490	COG3667	copper resistance
ABAYE_RS15495	COG2132	Multicopper oxidase
ABAYE_RS15505	COG0561	phosphatase activity
ABAYE_RS15510	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ABAYE_RS15520	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ABAYE_RS15535	COG1214	PFAM Peptidase M22, glycoprotease
ABAYE_RS15585	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ABAYE_RS15595	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ABAYE_RS15600	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ABAYE_RS15605	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ABAYE_RS15665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ABAYE_RS15675	COG1846	Transcriptional regulator
ABAYE_RS15680	COG1764	response to oxidative stress
ABAYE_RS15720	COG0037	tRNA processing
ABAYE_RS15730	COG0248	Ppx GppA phosphatase
ABAYE_RS15755	COG0072	phenylalanine-tRNA ligase activity
ABAYE_RS15790	COG1238	metal cluster binding
ABAYE_RS15795	COG0625	glutathione transferase activity
ABAYE_RS15810	COG0318	PFAM AMP-dependent synthetase and ligase
ABAYE_RS15815	COG3028	Belongs to the UPF0307 family
ABAYE_RS15820	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ABAYE_RS15840	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ABAYE_RS15845	COG0617	tRNA 3'-terminal CCA addition
ABAYE_RS15850	COG1555	photosystem II stabilization
ABAYE_RS15855	COG3956	TIGRFAM MazG family protein
ABAYE_RS15865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ABAYE_RS15885	COG0784	Response regulator, receiver
ABAYE_RS15885	COG2205	protein histidine kinase activity
ABAYE_RS15885	COG5002	protein histidine kinase activity
ABAYE_RS15890	COG1024	Enoyl-CoA hydratase
ABAYE_RS15895	COG2084	Dehydrogenase
ABAYE_RS15900	COG3622	Belongs to the hyi family
ABAYE_RS15930	COG0697	spore germination
ABAYE_RS15940	COG2814	Major facilitator Superfamily
ABAYE_RS15960	COG2132	Multicopper oxidase
ABAYE_RS15975	COG2205	protein histidine kinase activity
ABAYE_RS16065	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ABAYE_RS16075	COG0583	DNA-binding transcription factor activity
ABAYE_RS16080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ABAYE_RS16090	COG0084	hydrolase, TatD family'
ABAYE_RS16105	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ABAYE_RS16135	COG0440	acetolactate synthase activity
ABAYE_RS16140	COG0028	Belongs to the TPP enzyme family
ABAYE_RS16165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ABAYE_RS16170	COG1136	(ABC) transporter
ABAYE_RS16170	COG0577	efflux transmembrane transporter activity
ABAYE_RS16175	COG1538	Outer membrane efflux protein
ABAYE_RS16190	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ABAYE_RS16195	COG1162	GTPase activity
ABAYE_RS16205	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ABAYE_RS16245	COG1426	Protein conserved in bacteria
ABAYE_RS16280	COG0793	Belongs to the peptidase S41A family
ABAYE_RS16295	COG2267	carboxylic ester hydrolase activity
ABAYE_RS16305	COG1012	belongs to the aldehyde dehydrogenase family
ABAYE_RS16310	COG3265	gluconokinase activity
ABAYE_RS16320	COG0800	Aldolase
ABAYE_RS16330	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ABAYE_RS16335	COG0280	phosphate acetyltransferase
ABAYE_RS16335	COG0857	belongs to the CobB CobQ family
ABAYE_RS16340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ABAYE_RS16340	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ABAYE_RS16360	COG0740	serine-type endopeptidase activity
ABAYE_RS16370	COG4774	siderophore transport
ABAYE_RS16380	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ABAYE_RS16390	COG2813	Specifically methylates the guanine in position
ABAYE_RS16390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ABAYE_RS16520	COG0788	formyltetrahydrofolate deformylase activity
ABAYE_RS16545	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABAYE_RS16545	COG4651	solute:proton antiporter activity
ABAYE_RS16565	COG0724	RNA recognition motif
ABAYE_RS16570	COG0210	DNA helicase
ABAYE_RS16595	COG1733	regulation of RNA biosynthetic process
ABAYE_RS16605	COG2900	Belongs to the SlyX family
ABAYE_RS16610	COG0488	(ABC) transporter
ABAYE_RS16615	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS16620	COG1560	Kdo2-lipid A biosynthetic process
ABAYE_RS16630	COG1301	dicarboxylic acid transport
ABAYE_RS16685	COG0473	3-isopropylmalate dehydrogenase activity
ABAYE_RS16740	COG0583	DNA-binding transcription factor activity
ABAYE_RS16750	COG0625	glutathione transferase activity
ABAYE_RS16755	COG2378	regulation of single-species biofilm formation
ABAYE_RS16760	COG0546	phosphoglycolate phosphatase activity
ABAYE_RS16775	COG1530	ribonuclease E activity
ABAYE_RS16780	COG0318	PFAM AMP-dependent synthetase and ligase
ABAYE_RS16795	COG0583	DNA-binding transcription factor activity
ABAYE_RS16800	COG4221	oxidoreductase activity
ABAYE_RS16805	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ABAYE_RS16815	COG0534	Mate efflux family protein
ABAYE_RS16830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ABAYE_RS16855	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ABAYE_RS16855	COG0493	'glutamate synthase
ABAYE_RS16865	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ABAYE_RS16870	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ABAYE_RS16885	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ABAYE_RS16895	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ABAYE_RS16895	COG0644	oxidoreductase
ABAYE_RS16905	COG0425	Belongs to the sulfur carrier protein TusA family
ABAYE_RS16910	COG4535	Mg2 and Co2 transporter CorC
ABAYE_RS16920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ABAYE_RS16940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ABAYE_RS16945	COG0475	glutathione-regulated potassium exporter activity
ABAYE_RS16945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ABAYE_RS16960	COG0484	heat shock protein binding
ABAYE_RS16965	COG0789	Transcriptional regulator
ABAYE_RS16970	COG0598	Magnesium transport protein CorA
ABAYE_RS16985	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ABAYE_RS16990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ABAYE_RS16995	COG1074	ATP-dependent DNA helicase activity
ABAYE_RS17000	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ABAYE_RS17020	COG2226	methyltransferase
ABAYE_RS17035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ABAYE_RS17040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ABAYE_RS17055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ABAYE_RS17055	COG2111	Na H antiporter
ABAYE_RS17060	COG1006	Multisubunit Na H antiporter MnhC subunit
ABAYE_RS17065	COG0651	ATP synthesis coupled electron transport
ABAYE_RS17070	COG1863	multisubunit Na H antiporter MnhE subunit
ABAYE_RS17075	COG2212	antiporter activity
ABAYE_RS17080	COG1320	monovalent cation:proton antiporter activity
ABAYE_RS17095	COG0195	Participates in both transcription termination and antitermination
ABAYE_RS17145	COG0237	dephospho-CoA kinase activity
ABAYE_RS17155	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ABAYE_RS17170	COG0497	DNA recombination
ABAYE_RS17180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ABAYE_RS17210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ABAYE_RS17210	COG2169	Transcriptional regulator
ABAYE_RS17215	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ABAYE_RS17275	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ABAYE_RS17290	COG0326	Molecular chaperone. Has ATPase activity
ABAYE_RS17305	COG2056	Na+-H+ antiporter family
ABAYE_RS17405	COG0546	phosphoglycolate phosphatase activity
ABAYE_RS17410	COG1716	ATPase activity
ABAYE_RS17455	COG0181	hydroxymethylbilane synthase activity
ABAYE_RS17465	COG3275	phosphorelay sensor kinase activity
ABAYE_RS17485	COG1538	Outer membrane efflux protein
ABAYE_RS17490	COG0697	spore germination
ABAYE_RS17515	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ABAYE_RS17520	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ABAYE_RS17525	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ABAYE_RS17530	COG0772	Belongs to the SEDS family
ABAYE_RS17555	COG4974	Belongs to the 'phage' integrase family
ABAYE_RS17560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABAYE_RS17570	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ABAYE_RS17580	COG2197	response regulator
ABAYE_RS17595	COG0793	Belongs to the peptidase S41A family
ABAYE_RS17600	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ABAYE_RS17605	COG0795	lipopolysaccharide-transporting ATPase activity
ABAYE_RS17645	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABAYE_RS17645	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ABAYE_RS17655	COG0004	ammonium transporteR
ABAYE_RS17660	COG0347	Belongs to the P(II) protein family
ABAYE_RS17670	COG0606	chelatase, subunit chli
ABAYE_RS17680	COG0659	secondary active sulfate transmembrane transporter activity
ABAYE_RS17705	COG0789	Transcriptional regulator
ABAYE_RS17720	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABAYE_RS17815	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ABAYE_RS17835	COG1662	PFAM IS1 transposase
ABAYE_RS17870	COG0697	spore germination
ABAYE_RS17890	COG0789	Transcriptional regulator
ABAYE_RS18135	COG0789	Transcriptional regulator
ABAYE_RS18140	COG0589	response to stress
ABAYE_RS18150	COG0640	Transcriptional regulator
ABAYE_RS18160	COG0798	PFAM Bile acid sodium symporter
ABAYE_RS18165	COG0431	NADPH-dependent FMN reductase
ABAYE_RS18170	COG0492	ferredoxin-NADP+ reductase activity
ABAYE_RS18175	COG2072	flavoprotein involved in K transport
ABAYE_RS18205	COG0606	chelatase, subunit chli
ABAYE_RS18210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ABAYE_RS18220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ABAYE_RS18235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ABAYE_RS18250	COG0318	PFAM AMP-dependent synthetase and ligase
ABAYE_RS18260	COG0477	Major facilitator Superfamily
ABAYE_RS18265	COG2860	membrane
ABAYE_RS18270	COG3012	SEC-C Motif Domain Protein
ABAYE_RS18275	COG1253	flavin adenine dinucleotide binding
ABAYE_RS18285	COG0477	Major facilitator Superfamily
ABAYE_RS18295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ABAYE_RS18330	COG0655	NAD(P)H dehydrogenase (quinone) activity
ABAYE_RS18340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ABAYE_RS18375	COG1309	transcriptional regulator
ABAYE_RS18410	COG0758	DNA mediated transformation
ABAYE_RS18420	COG0697	spore germination
ABAYE_RS18425	COG1309	transcriptional regulator
ABAYE_RS18440	COG0386	Belongs to the glutathione peroxidase family
ABAYE_RS18505	COG1121	(ABC) transporter
ABAYE_RS18510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ABAYE_RS18515	COG1280	lysine exporter protein (LysE YggA)
ABAYE_RS18520	COG2837	iron assimilation
ABAYE_RS18525	COG0281	malic enzyme
ABAYE_RS18570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ABAYE_RS18570	COG0519	Catalyzes the synthesis of GMP from XMP
ABAYE_RS18575	COG4399	Belongs to the UPF0754 family
ABAYE_RS18580	COG2259	Doxx family
ABAYE_RS18585	COG0586	Pfam SNARE associated Golgi protein
ABAYE_RS18600	COG1192	Involved in chromosome partitioning
ABAYE_RS18610	COG0271	Belongs to the BolA IbaG family
ABAYE_RS18630	COG2267	carboxylic ester hydrolase activity
ABAYE_RS18650	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ABAYE_RS18650	COG3321	synthase
ABAYE_RS18650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ABAYE_RS18650	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
ABAYE_RS18655	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS18665	COG2197	response regulator
ABAYE_RS18675	COG3916	Acyl-homoserine-lactone synthase
ABAYE_RS18680	COG0477	Major facilitator Superfamily
ABAYE_RS18685	COG1024	Enoyl-CoA hydratase
ABAYE_RS18690	COG1024	Enoyl-CoA hydratase
ABAYE_RS18695	COG1960	acyl-CoA dehydrogenase activity
ABAYE_RS18700	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ABAYE_RS18720	COG1113	amino acid transport
ABAYE_RS18725	COG1113	amino acid transport
ABAYE_RS18730	COG0251	oxidation-reduction process
ABAYE_RS18770	COG0564	pseudouridine synthase activity
ABAYE_RS18810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ABAYE_RS18825	COG1802	Transcriptional regulator
ABAYE_RS18830	COG1448	Aminotransferase
ABAYE_RS18835	COG0277	FAD linked oxidase domain protein
ABAYE_RS18845	COG2186	Transcriptional regulator
ABAYE_RS18855	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ABAYE_RS18870	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ABAYE_RS18880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ABAYE_RS18890	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ABAYE_RS18895	COG0438	transferase activity, transferring glycosyl groups
ABAYE_RS18910	COG0438	transferase activity, transferring glycosyl groups
ABAYE_RS18925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ABAYE_RS18955	COG0728	peptidoglycan biosynthetic process
ABAYE_RS18960	COG3023	N-Acetylmuramoyl-L-alanine amidase
ABAYE_RS19015	COG0546	phosphoglycolate phosphatase activity
ABAYE_RS19020	COG1028	Short-chain dehydrogenase reductase Sdr
ABAYE_RS19040	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABAYE_RS19045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ABAYE_RS19050	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ABAYE_RS19055	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ABAYE_RS19060	COG1116	anion transmembrane transporter activity
ABAYE_RS19065	COG1309	transcriptional regulator
ABAYE_RS19070	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ABAYE_RS19090	COG0196	riboflavin kinase activity
ABAYE_RS19095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ABAYE_RS19105	COG1047	Peptidyl-prolyl cis-trans
ABAYE_RS19145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ABAYE_RS19150	COG0657	acetylesterase activity
ABAYE_RS19170	COG0583	DNA-binding transcription factor activity
ABAYE_RS19200	COG2951	lytic endotransglycosylase activity
ABAYE_RS19205	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ABAYE_RS19220	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ABAYE_RS19230	COG0671	phosphoesterase, PA-phosphatase related
ABAYE_RS19235	COG0861	Integral membrane protein TerC family
ABAYE_RS19245	COG0754	glutathionylspermidine amidase activity
ABAYE_RS19255	COG0402	S-adenosylhomocysteine deaminase activity
ABAYE_RS19275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ABAYE_RS19310	COG1230	cation diffusion facilitator family transporter
ABAYE_RS19325	COG0706	membrane insertase activity