locus-tag class description HIN87_RS00030 ENOG4105M7P phage repressor HIN87_RS00090 ENOG4105DA5 (ABC) transporter HIN87_RS00095 ENOG4105E3A (ABC) transporter HIN87_RS00110 ENOG4105CNI cell division protein FtsW HIN87_RS00115 ENOG4105CVE Lytic murein transglycosylase HIN87_RS00155 ENOG4105CE9 30S ribosomal protein S2 HIN87_RS00160 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HIN87_RS00170 ENOG4107RNU major facilitator superfamily MFS_1 HIN87_RS00180 ENOG4105DX1 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity) HIN87_RS00185 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) HIN87_RS00190 ENOG4107QPN acyl-Coa dehydrogenase HIN87_RS00205 ENOG4105C3E May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity) HIN87_RS00210 ENOG4105SYT Methylenetetrahydrofolate reductase HIN87_RS00215 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) HIN87_RS00220 ENOG4105BZU Histidine kinase HIN87_RS00225 ENOG4105C6K Malic enzyme HIN87_RS00235 ENOG4105C0H protease HIN87_RS00240 ENOG4107QNR UPF0135 protein HIN87_RS00245 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HIN87_RS00280 ENOG4105C4G Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity) HIN87_RS00295 ENOG4105DUX Transporter HIN87_RS00305 ENOG4105DFP Integrase HIN87_RS00345 ENOG4108R1E Serine threonine protein phosphatase 1 HIN87_RS00425 ENOG41090AG Bacteriophage protein HIN87_RS00445 ENOG4107ZQ5 Phage-associated protein, HI1409 family HIN87_RS00605 ENOG4105DDQ anthranilate synthase HIN87_RS00610 ENOG4105CD8 aminopeptidase N HIN87_RS00640 ENOG4105C7W Xanthine dehydrogenase HIN87_RS00650 ENOG4105EUJ GTP cyclohydrolase i HIN87_RS00670 ENOG4105NX3 Membrane HIN87_RS00685 ENOG4105E4F Isochorismate synthase HIN87_RS00700 ENOG4108JJ7 ABC transporter HIN87_RS00705 ENOG4105BZ1 (ABC) transporter HIN87_RS00720 ENOG4105WQI isochorismatase HIN87_RS00725 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase HIN87_RS00730 ENOG4105C0W non-ribosomal peptide synthetase HIN87_RS00750 ENOG4108IPW abc transporter atp-binding protein HIN87_RS00765 ENOG4105CEY Amp-dependent synthetase and ligase HIN87_RS00780 ENOG4105WWK YheO domain protein HIN87_RS00790 ENOG4105C2I pirin domain protein HIN87_RS00810 ENOG4105VCD cytoplasmic protein HIN87_RS00815 ENOG4105D22 carbon starvation protein HIN87_RS00825 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein HIN87_RS00835 ENOG41066DG (EAL) domain protein HIN87_RS00845 ENOG4105DHU Bile acid HIN87_RS00860 ENOG4105DAN ATP-dependent protease HIN87_RS00865 ENOG4105EJC lysr family transcriptional regulator HIN87_RS00870 ENOG4108K5P (LipO)protein HIN87_RS00890 ENOG4105DZ1 carboxypeptidase HIN87_RS00895 ENOG4108Z0R Transferase HIN87_RS00915 ENOG4107QTF adenylosuccinate lyase HIN87_RS00930 ENOG4105ERU peptidase HIN87_RS00935 ENOG4105BZY Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity) HIN87_RS00945 ENOG4105C8U phosphate abc transporter HIN87_RS00950 ENOG4105CVA phosphate HIN87_RS00955 ENOG4105C85 amino acid HIN87_RS00960 ENOG4107RA9 decarboxylase HIN87_RS00965 ENOG4105F7P transcriptional regulator AsnC family HIN87_RS00975 ENOG4105DY8 decarboxylase HIN87_RS00980 ENOG4108JPW Aminotransferase HIN87_RS01005 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) HIN87_RS01020 ENOG4105BZK Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity) HIN87_RS01025 ENOG4105D3G Pseudouridine synthase HIN87_RS01040 ENOG4108UV6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity) HIN87_RS01070 ENOG4105JAB phenazine biosynthesis protein, phzf family HIN87_RS01075 ENOG4108ETY sodium dicarboxylate symporter HIN87_RS01080 ENOG4105EGI Transcriptional regulator HIN87_RS01085 ENOG4105CBP Major Facilitator HIN87_RS01110 ENOG4108R99 pseudouridine synthase HIN87_RS01115 ENOG4105E9K Isocitrate dehydrogenase HIN87_RS01125 ENOG4105DZ1 carboxypeptidase HIN87_RS01130 ENOG4105CEP NADH dehydrogenase HIN87_RS01135 ENOG4108YZY peptidylprolyl cis-trans isomerase HIN87_RS01140 ENOG4105CVP deoxyribo-dipyrimidine photolyase HIN87_RS01155 ENOG4107R8N Glycosyl transferase, family 2 HIN87_RS01185 ENOG4105EA8 2-Nitropropane dioxygenase HIN87_RS01190 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HIN87_RS01195 ENOG4107QS8 (LipO)protein HIN87_RS01230 ENOG4105DTR rard protein HIN87_RS01240 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) HIN87_RS01250 ENOG4105BZU Histidine kinase HIN87_RS01290 ENOG4105EMU Dehydrogenase HIN87_RS01295 ENOG4105FR9 TRNA-(Ms 2 io 6 A)-hydroxylase HIN87_RS01300 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) HIN87_RS01305 ENOG41071DT Involved in DNA repair and RecF pathway recombination (By similarity) HIN87_RS01315 ENOG4105CWT An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity) HIN87_RS01330 ENOG4105C3F Signal peptidase i HIN87_RS01340 ENOG41068WN HIN87_RS01350 ENOG4105C0H protease HIN87_RS01355 ENOG4108IYU L-aspartate oxidase HIN87_RS01370 ENOG4105HHA aminodeoxychorismate lyase HIN87_RS01375 ENOG4105YAZ 4-amino-4-deoxychorismate lyase HIN87_RS01380 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HIN87_RS01390 ENOG4108I5D sulfate abc transporter HIN87_RS01400 ENOG4108IJ6 ABC transporter HIN87_RS01405 ENOG4107R11 Transcriptional regulator HIN87_RS01420 ENOG4107VRB Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) HIN87_RS01425 ENOG4105FD2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity) HIN87_RS01440 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen HIN87_RS01455 ENOG4108UKI Enoyl-CoA hydratase HIN87_RS01465 ENOG4105C2C drug resistance transporter, Bcr CflA HIN87_RS01470 ENOG4108ETH Formylglycinamide ribotide synthetase HIN87_RS01490 ENOG4105CH2 amidohydrolase HIN87_RS01495 ENOG4107YD3 Thioesterase HIN87_RS01500 ENOG4105E02 MotA TolQ exbB proton channel HIN87_RS01505 ENOG4105M8F Biopolymer transport protein exbD tolR HIN87_RS01515 ENOG4107R6Y Involved in the TonB-independent uptake of proteins (By similarity) HIN87_RS01520 ENOG4105KCK Peptidoglycan-associated lipoprotein HIN87_RS01570 ENOG4105C02 permease HIN87_RS01580 ENOG4108V3E phosphoribosylglycinamide formyltransferase HIN87_RS01585 ENOG4107R6F Alpha Beta Hydrolase Fold protein HIN87_RS01590 ENOG4108E8C ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity) HIN87_RS01600 ENOG4105EGY DNA internalization-related competence protein ComEC Rec2 HIN87_RS01605 ENOG4105CQU Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity) HIN87_RS01610 ENOG4105D60 lipoprotein releasing system transmembrane protein HIN87_RS01645 ENOG4107KET secretion protein, HlyD family HIN87_RS01680 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HIN87_RS01685 ENOG4105C10 Electron transfer flavoprotein HIN87_RS01690 ENOG4105BZJ Electron transfer flavoprotein HIN87_RS01695 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HIN87_RS01700 ENOG4105N14 lysine exporter protein LysE YggA HIN87_RS01710 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) HIN87_RS01720 ENOG4105C85 amino acid HIN87_RS01725 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) HIN87_RS01735 ENOG4105CAP With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity) HIN87_RS01750 ENOG4107H9G Necessary for formate dehydrogenase activity (By similarity) HIN87_RS01755 ENOG4107QKC Oxidoreductase alpha (molybdopterin) subunit HIN87_RS01760 ENOG4105BZW Glycerate kinase HIN87_RS01830 ENOG4105CEY Amp-dependent synthetase and ligase HIN87_RS01845 ENOG4108RRZ Transcription elongation factor GreB HIN87_RS01865 ENOG4105E4C Lytic transglycosylase catalytic HIN87_RS01880 ENOG4105BZS acriflavin resistance protein HIN87_RS01885 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase HIN87_RS01895 ENOG41080IJ Diacylglycerol kinase HIN87_RS01965 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HIN87_RS01980 ENOG4105C6V Glycerol-3-phosphate dehydrogenase HIN87_RS01985 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) HIN87_RS01990 ENOG4105CSH Transporter HIN87_RS02040 ENOG4105EEI dihydropteroate synthase HIN87_RS02045 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) HIN87_RS02055 ENOG4105HBR Rna-binding protein HIN87_RS02070 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain HIN87_RS02075 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain HIN87_RS02090 ENOG41080TK Universal stress protein HIN87_RS02105 ENOG4105PNM synthesis protein HIN87_RS02120 ENOG4105EEQ Na H antiporter HIN87_RS02125 ENOG4105CGZ zinc metallopeptidase HIN87_RS02130 ENOG4105CKW Inner membrane protein yedI HIN87_RS02140 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha HIN87_RS02150 ENOG4107QN2 dihydrolipoyl dehydrogenase HIN87_RS02155 ENOG4105C7S Dehydrogenase HIN87_RS02160 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 HIN87_RS02175 ENOG4105E33 succinate dehydrogenase HIN87_RS02185 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein HIN87_RS02190 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit HIN87_RS02220 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HIN87_RS02225 ENOG41084BA UPF0250 protein HIN87_RS02230 ENOG4108BDP Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity) HIN87_RS02245 ENOG4105CUB amino acid HIN87_RS02255 ENOG4105KVH Transcriptional regulator HIN87_RS02260 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) HIN87_RS02265 ENOG4105CB8 Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity) HIN87_RS02280 ENOG4107Y7W Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity) HIN87_RS02310 ENOG410841Q phosphoesterase PA-phosphatase related protein HIN87_RS02315 ENOG4105C1P efflux transporter, rnd family, mfp subunit HIN87_RS02320 ENOG4105BZS acriflavin resistance protein HIN87_RS02325 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HIN87_RS02330 ENOG4105K8R UPF0145 protein HIN87_RS02335 ENOG4105K8R UPF0145 protein HIN87_RS02355 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) HIN87_RS02375 ENOG4108M0I Transcriptional regulator HIN87_RS02390 ENOG4105DHQ Histidine kinase HIN87_RS02395 ENOG4105XJC Two component transcriptional regulator (Winged helix family HIN87_RS02400 ENOG4105DIJ Phosphoethanolamine transferase HIN87_RS02420 ENOG4105D78 K07001 NTE family protein HIN87_RS02435 ENOG4105MSB protein, conserved in bacteria HIN87_RS02440 ENOG4105CTB Polyprenyl synthetase HIN87_RS02445 ENOG4105C7F AcnD-accessory protein PrpF HIN87_RS02450 ENOG4105C85 amino acid HIN87_RS02645 ENOG4105RDA repressor HIN87_RS02715 ENOG4105CF7 AraC family transcriptional regulator HIN87_RS02740 ENOG4108X0B nad(p)h dehydrogenase (quinone) HIN87_RS02750 ENOG4105ECA phosphoserine phosphatase homoserine phosphotransferase bifunctional protein HIN87_RS02760 ENOG4105D8T Acyltransferase HIN87_RS02770 ENOG4105C03 ribonuclease HIN87_RS02775 ENOG4108Z03 MAF-like protein HIN87_RS02780 ENOG4105VQ7 Rod shape-determining protein MreD HIN87_RS02785 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) HIN87_RS02795 ENOG41080G2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) HIN87_RS02805 ENOG4105CHT Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity) HIN87_RS02835 ENOG4105C7B Threonine dehydratase HIN87_RS02840 ENOG4105D78 K07001 NTE family protein HIN87_RS02845 ENOG4105BZG amino acid carrier protein HIN87_RS02865 ENOG4105C2C drug resistance transporter, Bcr CflA HIN87_RS02870 ENOG4105EM2 membrane HIN87_RS02920 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein HIN87_RS02925 ENOG4105WD1 Membrane HIN87_RS02935 ENOG4107PEH Entericidin EcnA/B family HIN87_RS02950 ENOG4105CBS Chea signal transduction histidine kinase HIN87_RS02955 ENOG4105C8Q Methyl-accepting chemotaxis HIN87_RS02960 ENOG4108ZGA chew protein HIN87_RS02965 ENOG4105M3Z response regulator HIN87_RS02970 ENOG4108UNF response regulator HIN87_RS02995 ENOG4105KWI UPF0339 protein HIN87_RS03000 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA HIN87_RS03005 ENOG4105K78 MarR family Transcriptional regulator HIN87_RS03015 ENOG4106XY2 Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity) HIN87_RS03020 ENOG4105T95 Thiol disulfide interChange protein HIN87_RS03030 ENOG4108N2Y auxin Efflux HIN87_RS03035 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HIN87_RS03040 ENOG4105CHB tonB-dependent Receptor HIN87_RS03045 ENOG4108VX5 3-methyladenine DNA glycosylase HIN87_RS03055 ENOG4107UUG Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity) HIN87_RS03070 ENOG4105CI3 gtp-binding protein typa HIN87_RS03075 ENOG4105C2W permease HIN87_RS03085 ENOG4108IQI permease HIN87_RS03090 ENOG4105E0Y RtcB Protein HIN87_RS03100 ENOG4108WHA ompa motb domain protein HIN87_RS03110 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS03120 ENOG410814C multidrug resistance protein HIN87_RS03130 ENOG4105ET1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity) HIN87_RS03135 ENOG4105DZG Dehydrogenase HIN87_RS03140 ENOG4105TW1 Carbohydrate-selective porin OprB HIN87_RS03150 ENOG4108R6W Transcriptional regulator, ARAC family HIN87_RS03155 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS03185 ENOG4108UT2 hemolysin iii HIN87_RS03190 ENOG4105CSH Transporter HIN87_RS03205 ENOG4105D3R alkyl hydroperoxide reductase HIN87_RS03225 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase HIN87_RS03270 ENOG4105CHI Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity) HIN87_RS03275 ENOG4108WBT adenosyltransferase HIN87_RS03295 ENOG4105CNG UPF0061 protein HIN87_RS03300 ENOG4105E3W Two component transcriptional regulator (Winged helix family HIN87_RS03305 ENOG4105EB3 Histidine kinase HIN87_RS03315 ENOG4105CSU acyl-Coa dehydrogenase HIN87_RS03320 ENOG4105CSU acyl-Coa dehydrogenase HIN87_RS03325 ENOG4108VY7 phosphate-starvation-inducible protein PsiE HIN87_RS03345 ENOG4105UGU tonB-dependent Receptor HIN87_RS03365 ENOG4107XU6 Glycosyl transferase (Group 1 HIN87_RS03370 ENOG4105K64 Glycosyl transferase, family 2 HIN87_RS03375 ENOG4105CG5 Glycosyl transferase (Group 1 HIN87_RS03395 ENOG4107TYR Glycosyl Transferase HIN87_RS03400 ENOG4107BJW polysaccharide deacetylase HIN87_RS03410 ENOG4105CM2 brancheD-chain amino acid aminotransferase HIN87_RS03415 ENOG4105CE6 Adenylation and deadenylation of glutamate--ammonia ligase (By similarity) HIN87_RS03420 ENOG4105BZU Histidine kinase HIN87_RS03460 ENOG4105VIE preprotein translocase, subunit YajC HIN87_RS03465 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HIN87_RS03470 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) HIN87_RS03475 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase HIN87_RS03485 ENOG4105FFC UPF0187 protein HIN87_RS03490 ENOG4105DB7 PHP domain protein HIN87_RS03500 ENOG4105K9H YciI-like protein HIN87_RS03530 ENOG4105NAU thioesterase Superfamily protein HIN87_RS03540 ENOG4107U2T alpha beta HIN87_RS03555 ENOG4107QN2 dihydrolipoyl dehydrogenase HIN87_RS03590 ENOG4108KHX Diguanylate cyclase HIN87_RS03595 ENOG4105UYK outer membrane protein a HIN87_RS03605 ENOG4107RZC phospholipase d HIN87_RS03615 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) HIN87_RS03635 ENOG4105DDT Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity) HIN87_RS03640 ENOG4105D1X Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity) HIN87_RS03645 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) HIN87_RS03655 ENOG4108UJD 30S ribosomal protein S9 HIN87_RS03660 ENOG4107MKT Stringent starvation protein a HIN87_RS03665 ENOG4105KB2 stringent starvation protein b HIN87_RS03680 ENOG4105E39 Enoyl-CoA hydratase HIN87_RS03685 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS03690 ENOG4107QX3 carboxylase HIN87_RS03705 ENOG4108RZE Tetr family transcriptional regulator HIN87_RS03710 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS03755 ENOG4106PT6 cdpdiacylglycerol-serine O-phosphatidyltransferase HIN87_RS03760 ENOG4105D6S protein involved in catabolism of external DNA HIN87_RS03790 ENOG4105E4C Lytic transglycosylase catalytic HIN87_RS03800 ENOG4105C9A Phoh family HIN87_RS03830 ENOG4105CS1 NAD(P)H quinone oxidoreductase HIN87_RS03835 ENOG4107S2Z UPF0761 membrane protein HIN87_RS03845 ENOG4108K2B transcriptional regulator HIN87_RS03850 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase HIN87_RS03895 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) HIN87_RS03900 ENOG4105DGW oligopeptidase A HIN87_RS03905 ENOG4105VKU nucleicacid-binding protein HIN87_RS03940 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS03980 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) HIN87_RS04090 ENOG41089BK Glutamine amido-transferase HIN87_RS04100 ENOG4105D7A ATP-binding protein HIN87_RS04110 ENOG4105KPV Transcriptional regulator HIN87_RS04125 ENOG4105CK2 sodium dicarboxylate symporter HIN87_RS04130 ENOG4105C29 acyl-CoA thioesterase HIN87_RS04150 ENOG4105CB5 ATP-dependent DNA helicase recG HIN87_RS04155 ENOG4105MJ2 Competence protein HIN87_RS04165 ENOG4108URH decarboxylase HIN87_RS04170 ENOG4105D7N magnesium and cobalt transport protein CorA HIN87_RS04180 ENOG4105E3I toluene tolerance HIN87_RS04190 ENOG4105CY3 ABC transporter, permease HIN87_RS04195 ENOG4105DHJ ABC, transporter HIN87_RS04205 ENOG4105C1J atp-dependent rna helicase HIN87_RS04210 ENOG4105ECY inositol monophosphatase HIN87_RS04225 ENOG4105DBS Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity) HIN87_RS04240 ENOG4105CSU acyl-Coa dehydrogenase HIN87_RS04250 ENOG41067S9 phage shock protein C, PspC HIN87_RS04255 ENOG4105W87 Cbs domain HIN87_RS04335 ENOG4105C26 Dehydrogenase HIN87_RS04345 ENOG4105C8Y Acetylornithine aminotransferase HIN87_RS04350 ENOG4105D82 Glutamate dehydrogenase HIN87_RS04355 ENOG4108IQI permease HIN87_RS04385 ENOG4107SKI cobyrinic Acid a,c-diamide synthase HIN87_RS04390 ENOG4105IPI Membrane HIN87_RS04395 ENOG4108Z7T Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) HIN87_RS04400 ENOG4105EM2 membrane HIN87_RS04405 ENOG4107QF7 multi-drug HIN87_RS04415 ENOG4105NF4 modulator of drug activity HIN87_RS04420 ENOG4105VRH Antibiotic biosynthesis monooxygenase HIN87_RS04430 ENOG4105CQB FAD linked oxidase domain protein HIN87_RS04435 ENOG4108JQ1 Dehydrogenase HIN87_RS04460 ENOG4105D0T Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity) HIN87_RS04465 ENOG4105MGK May be involved in the folding of the extracellular lipase during its passage through the periplasm (By similarity) HIN87_RS04470 ENOG4107IFA Lipase (EC 3.1.1.3) HIN87_RS04485 ENOG4108ZR6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity) HIN87_RS04500 ENOG4108VAU general secretion pathway protein G HIN87_RS04535 ENOG4108UHA Essential for recycling GMP and indirectly, cGMP (By similarity) HIN87_RS04550 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HIN87_RS04555 ENOG4105KME endoribonuclease L-psp HIN87_RS04565 ENOG4108UQY Iron-storage protein HIN87_RS04570 ENOG4108YSG O-Antigen polymerase HIN87_RS04590 ENOG4105HA9 of methanol dehydrogenase type HIN87_RS04595 ENOG4108V0P LemA family HIN87_RS04605 ENOG4105BZ8 glutamate synthase HIN87_RS04610 ENOG4105CBC glutamate synthase HIN87_RS04630 ENOG4105E4G Type IV pilus HIN87_RS04655 ENOG4108JQC penicillin-binding protein 1A HIN87_RS04660 ENOG4105DHI Methyltransferase HIN87_RS04675 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) HIN87_RS04680 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) HIN87_RS04685 ENOG4105CJN penicillin-binding protein HIN87_RS04700 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein HIN87_RS04725 ENOG4108IQI permease HIN87_RS04790 ENOG4105C5H ABC transporter HIN87_RS04800 ENOG4105PDP Short chain dehydrogenase HIN87_RS04805 ENOG4105CHH sulfate transporter HIN87_RS04820 ENOG4105E0F Histidine kinase HIN87_RS04830 ENOG4105CYC Transferase HIN87_RS04835 ENOG4108R6G acetyltransferase HIN87_RS04860 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) HIN87_RS04880 ENOG4105BZ1 (ABC) transporter HIN87_RS04905 ENOG4105CUV Homoserine Kinase HIN87_RS04970 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein HIN87_RS04975 ENOG4105KVH Transcriptional regulator HIN87_RS05010 ENOG4108BRW Activates expression of the rhaSR operon in response to L-rhamnose (By similarity) HIN87_RS05015 ENOG4105CPC Aldo Keto reductase HIN87_RS05035 ENOG4106NZI LysR family Transcriptional regulator HIN87_RS05040 ENOG4105D94 Major Facilitator Superfamily HIN87_RS05065 ENOG4105EUB pirin domain protein HIN87_RS05070 ENOG4105CHJ isochorismatase hydrolase HIN87_RS05080 ENOG4105C26 Dehydrogenase HIN87_RS05085 ENOG4108JPW Aminotransferase HIN87_RS05095 ENOG4105C85 amino acid HIN87_RS05105 ENOG4108UMN azlc family HIN87_RS05115 ENOG4108C33 Resolvase HIN87_RS05125 ENOG4108F3G Type I restriction-modification system, R subunit HIN87_RS05165 ENOG4108UUM single-stranded DNA-binding protein HIN87_RS05170 ENOG4107RDB Major Facilitator HIN87_RS05180 ENOG4105DWF phosphomethylpyrimidine kinase HIN87_RS05185 ENOG4105RA2 Membrane HIN87_RS05195 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein HIN87_RS05200 ENOG4108WUH Transcriptional regulator, TetR family HIN87_RS05205 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) HIN87_RS05210 ENOG4105BZU Histidine kinase HIN87_RS05220 ENOG4105C94 Transporter HIN87_RS05230 ENOG4107QN1 sodium solute HIN87_RS05235 ENOG41062QD Membrane HIN87_RS05240 ENOG4105BZU Histidine kinase HIN87_RS05255 ENOG4108UZX fmn reductase HIN87_RS05260 ENOG4105FBW Monooxygenase HIN87_RS05270 ENOG4108W2Y isochorismatase HIN87_RS05275 ENOG4108IQF Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity) HIN87_RS05285 ENOG4105D64 Mechanosensitive ion channel HIN87_RS05295 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase HIN87_RS05300 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HIN87_RS05320 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) HIN87_RS05335 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HIN87_RS05350 ENOG4105E0K tonB-dependent siderophore receptor HIN87_RS05365 ENOG4107QSN dihydrolipoamide acetyltransferase HIN87_RS05370 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) HIN87_RS05375 ENOG41063SB peptidase HIN87_RS05390 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) HIN87_RS05395 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) HIN87_RS05400 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) HIN87_RS05420 ENOG4105D7Z glutathione synthase HIN87_RS05440 ENOG4105CGK Exodeoxyribonuclease III HIN87_RS05445 ENOG4105KUZ arsenate reductase HIN87_RS05460 ENOG4105BZU Histidine kinase HIN87_RS05465 ENOG4105CSG Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity) HIN87_RS05495 ENOG41084YZ Hydrolase HIN87_RS05510 ENOG41061H0 Monooxygenase HIN87_RS05520 ENOG4108Z2U ureidoglycolate hydrolase HIN87_RS05525 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HIN87_RS05530 ENOG4105IPS esterase HIN87_RS05590 ENOG4105CS6 Rhs element vgr protein HIN87_RS05600 ENOG4105D9M gamma-glutamylcysteine synthetase HIN87_RS05615 ENOG4106BRA Membrane HIN87_RS05620 ENOG4105CHM Aminotransferase HIN87_RS05625 ENOG4107QJQ Mate efflux family protein HIN87_RS05640 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HIN87_RS05645 ENOG4105BZU Histidine kinase HIN87_RS05660 ENOG4105KHC sulfurtransferase HIN87_RS05695 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) HIN87_RS05710 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) HIN87_RS05715 ENOG4108ZAI phosphatidylglycerophosphatase a HIN87_RS05725 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) HIN87_RS05730 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) HIN87_RS05735 ENOG4108YZS Had-superfamily hydrolase, subfamily ia, variant 1 HIN87_RS05745 ENOG41088SP formiminoglutamate hydrolase HIN87_RS05755 ENOG4105C85 amino acid HIN87_RS05770 ENOG41090B9 response to stress HIN87_RS05775 ENOG4105CZE histidine utilization repressor HIN87_RS05785 ENOG4105CKI cobalamin synthesis protein HIN87_RS05795 ENOG4105C85 amino acid HIN87_RS05805 ENOG4108RXX maleylacetoacetate isomerase HIN87_RS05825 ENOG4105EWC Purine nucleoside phosphorylase HIN87_RS05830 ENOG4107QI1 Mate efflux family protein HIN87_RS05835 ENOG4105C09 Bile acid HIN87_RS05840 ENOG4108RWI nicotinamidase HIN87_RS05845 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HIN87_RS05865 ENOG4105S64 Formate nitrite transporter HIN87_RS05870 ENOG4105D1H recombination factor protein RarA HIN87_RS05880 ENOG4108ZZ3 UPF0260 protein HIN87_RS05900 ENOG4105CEN a g-specific adenine glycosylase HIN87_RS05915 ENOG4108R3E Dna-3-methyladenine glycosylase i HIN87_RS05920 ENOG4105DQ4 alcohol dehydrogenase HIN87_RS05940 ENOG4105HEI LysR family (Transcriptional regulator HIN87_RS05945 ENOG4105CV8 reductase HIN87_RS05950 ENOG4105F27 Major Facilitator HIN87_RS05985 ENOG4105DJY efflux transporter, rnd family, mfp subunit HIN87_RS05990 ENOG4108IG5 Transcriptional regulator HIN87_RS06000 ENOG4105C2W permease HIN87_RS06005 ENOG4108W5M transcriptional regulator HIN87_RS06030 ENOG4105CYJ ribosomal RNA small subunit methyltransferase B HIN87_RS06040 ENOG4105C8J )-transporter HIN87_RS06080 ENOG4105DA0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) HIN87_RS06085 ENOG4105ED7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity) HIN87_RS06090 ENOG4105D74 hydrolase HIN87_RS06100 ENOG4108821 RND type efflux pump HIN87_RS06105 ENOG4108821 RND type efflux pump HIN87_RS06110 ENOG4108821 RND type efflux pump HIN87_RS06115 ENOG4105C5H ABC transporter HIN87_RS06120 ENOG4105DQR SNARE associated Golgi HIN87_RS06130 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HIN87_RS06140 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HIN87_RS06165 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins HIN87_RS06180 ENOG4105PGM cation diffusion facilitator family transporter HIN87_RS06215 ENOG4108BUD transposase HIN87_RS06225 ENOG4105I1F Resistance protein HIN87_RS06235 ENOG4108BUD transposase HIN87_RS06255 ENOG4108UGV hypoxanthine phosphoribosyltransferase HIN87_RS06260 ENOG4107QUY Guanine deaminase HIN87_RS06270 ENOG4106032 Glutathionylspermidine synthase HIN87_RS06280 ENOG4105DU1 integral membrane protein, terc HIN87_RS06285 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase HIN87_RS06295 ENOG4105DFU Cell wall formation (By similarity) HIN87_RS06305 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) HIN87_RS06310 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit HIN87_RS06315 ENOG4105CVE Lytic murein transglycosylase HIN87_RS06370 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) HIN87_RS06410 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase HIN87_RS06420 ENOG4105C07 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity) HIN87_RS06425 ENOG4105DTN riboflavin biosynthesis protein ribF HIN87_RS06435 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) HIN87_RS06440 ENOG4108R86 Transcriptional regulator HIN87_RS06445 ENOG4108VM9 ABC, transporter HIN87_RS06450 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HIN87_RS06455 ENOG4105D4R Catalyzes the desulfonation of aliphatic sulfonates (By similarity) HIN87_RS06460 ENOG4105GVF (ABC) transporter HIN87_RS06465 ENOG4105GVF (ABC) transporter HIN87_RS06470 ENOG4107QZM n-acetylglutamate synthase HIN87_RS06485 ENOG4105UBK short-chain dehydrogenase reductase HIN87_RS06490 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HIN87_RS06500 ENOG4108Z33 Thiol disulfide Interchange Protein HIN87_RS06505 ENOG41062JF Transcriptional regulator HIN87_RS06530 ENOG4105HSS phospholipase C HIN87_RS06540 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase HIN87_RS06545 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase HIN87_RS06550 ENOG4105CJR Integral membrane protein (MviN HIN87_RS06555 ENOG4108V1T peptidylprolyl cis-trans isomerase HIN87_RS06560 ENOG4108V1T peptidylprolyl cis-trans isomerase HIN87_RS06565 ENOG4105D75 Capsular exopolysaccharide family HIN87_RS06575 ENOG4105DAY polysaccharide export protein HIN87_RS06580 ENOG4107QQG Dehydrogenase HIN87_RS06590 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) HIN87_RS06610 ENOG4105K64 Glycosyl transferase, family 2 HIN87_RS06615 ENOG4105CG5 Glycosyl transferase (Group 1 HIN87_RS06620 ENOG4105CPK Glycosyl transferase (Group 1 HIN87_RS06630 ENOG4105D3Q Sugar transferase HIN87_RS06635 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase HIN87_RS06640 ENOG4105C6Y Udp-glucose 6-dehydrogenase HIN87_RS06650 ENOG4105CMR udp-glucose 4-epimerase HIN87_RS06660 ENOG4107QKV phosphomannomutase HIN87_RS06665 ENOG4105DAA L-lactate HIN87_RS06670 ENOG41073TP transcriptional regulator HIN87_RS06680 ENOG4105CXG d-lactate dehydrogenase HIN87_RS06685 ENOG4105CGF Aromatic amino acid aminotransferase HIN87_RS06695 ENOG4105DRR Transcriptional regulator, GntR family HIN87_RS06700 ENOG4105CR4 methylisocitrate lyase HIN87_RS06705 ENOG4105BZN citrate synthase HIN87_RS06710 ENOG4108I0Z Aconitate hydratase HIN87_RS06765 ENOG4105D3G Pseudouridine synthase HIN87_RS06790 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS06805 ENOG4105M4H endoribonuclease L-psp HIN87_RS06810 ENOG4105C85 amino acid HIN87_RS06815 ENOG4105C85 amino acid HIN87_RS06825 ENOG4105C26 Dehydrogenase HIN87_RS06830 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HIN87_RS06840 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS06845 ENOG4105E39 Enoyl-CoA hydratase HIN87_RS06850 ENOG4105E39 Enoyl-CoA hydratase HIN87_RS06855 ENOG4105CSH Transporter HIN87_RS06880 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS06925 ENOG4107PSF BolA-like protein HIN87_RS06935 ENOG4107QJE Chromosome Partitioning Protein HIN87_RS06950 ENOG4105DQR SNARE associated Golgi HIN87_RS06955 ENOG4108VBZ doxx family HIN87_RS06960 ENOG4106MP8 UPF0754 membrane protein HIN87_RS06965 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) HIN87_RS06985 ENOG4105EUB pirin domain protein HIN87_RS07010 ENOG4107R1I NAD-dependent malic enzyme HIN87_RS07015 ENOG4105EZR dyp-type peroxidase family protein HIN87_RS07020 ENOG410829K Lysine exporter protein (Lyse ygga) HIN87_RS07025 ENOG4105FAV ABC, transporter HIN87_RS07030 ENOG4105FDK ABC transporter HIN87_RS07095 ENOG4108V06 Glutathione peroxidase HIN87_RS07105 ENOG4107RTG Major Facilitator superfamily HIN87_RS07110 ENOG4108IND Tetr family transcriptional regulator HIN87_RS07125 ENOG4105C79 DNA protecting protein DprA HIN87_RS07160 ENOG4105Y7M Transcriptional regulator, TetR family HIN87_RS07195 ENOG4105C6T cysteine synthase HIN87_RS07210 ENOG4105CS1 NAD(P)H quinone oxidoreductase HIN87_RS07230 ENOG4105CCT upf0313 protein HIN87_RS07245 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HIN87_RS07255 ENOG4105C0R drug resistance transporter emrb qaca subfamily HIN87_RS07260 ENOG4108URH decarboxylase HIN87_RS07265 ENOG4105EE5 Membrane protein terC HIN87_RS07275 ENOG4105EN6 Membrane HIN87_RS07280 ENOG41079KZ Major Facilitator Superfamily HIN87_RS07285 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) HIN87_RS07290 ENOG4105CEY Amp-dependent synthetase and ligase HIN87_RS07305 ENOG4105F0N pyrophosphate phospho-hydrolase HIN87_RS07310 ENOG4105EPF Outer membrane porin HIN87_RS07320 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HIN87_RS07330 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HIN87_RS07335 ENOG4105C0P Mg chelatase subunit ChlI HIN87_RS07365 ENOG4105H3G oxidoreductase HIN87_RS07370 ENOG4105C3M thioredoxin reductase HIN87_RS07375 ENOG4105CAU Arsenical resistance protein, ArsH HIN87_RS07380 ENOG4105D6J arsenicaL-resistance protein HIN87_RS07390 ENOG4105KBH arsR family transcriptional regulator HIN87_RS07405 ENOG4105W1Y Transcriptional regulator HIN87_RS07490 ENOG4105W1Y Transcriptional regulator HIN87_RS07515 ENOG4105CHH sulfate transporter HIN87_RS07525 ENOG4105C0P Mg chelatase subunit ChlI HIN87_RS07540 ENOG4105BZU Histidine kinase HIN87_RS07550 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) HIN87_RS07590 ENOG4108K5H permease YjgP YjgQ family protein HIN87_RS07595 ENOG4105CJI Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity) HIN87_RS07600 ENOG4105CN1 protease HIN87_RS07605 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HIN87_RS07610 ENOG4107TUY Histidine kinase HIN87_RS07620 ENOG41061WM D-Alanyl-D-Alanine HIN87_RS07630 ENOG4105D6E homoserine dehydrogenase HIN87_RS07635 ENOG4105T95 Thiol disulfide interChange protein HIN87_RS07640 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) HIN87_RS07650 ENOG4105CE1 Ferrous iron transport protein b HIN87_RS07665 ENOG4105CNI cell division protein FtsW HIN87_RS07670 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) HIN87_RS07680 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) HIN87_RS07705 ENOG4108RNG Permease of the drug metabolite transporter HIN87_RS07710 ENOG4105DFG type I secretion outer membrane protein HIN87_RS07715 ENOG4108UTW Plays a role in the regulation of phosphate uptake HIN87_RS07730 ENOG4108HRK Histidine kinase HIN87_RS07735 ENOG4108NEV two component transcriptional regulator, LytTR family HIN87_RS07740 ENOG4105D6W Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity) HIN87_RS07765 ENOG4105VFQ Histone family protein nucleoid-structuring protein H-NS HIN87_RS07780 ENOG4105GVR general secretion pathway protein D HIN87_RS07785 ENOG4105TV9 FHA Domain-Containing protein HIN87_RS07790 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) HIN87_RS07830 ENOG4105PM1 preprotein translocase subunit SecE HIN87_RS07835 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) HIN87_RS07885 ENOG4105D3C The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity) HIN87_RS07890 ENOG4105D3Y Na H antiporter HIN87_RS07905 ENOG4105CJX Molecular chaperone. Has ATPase activity (By similarity) HIN87_RS07920 ENOG4107ZXU DSBA oxidoreductase HIN87_RS07975 ENOG4105BZQ cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase HIN87_RS07980 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HIN87_RS08010 ENOG4107Y66 Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity) HIN87_RS08020 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) HIN87_RS08035 ENOG4105C2N RNA methyltransferase TrmH family group 3 HIN87_RS08045 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) HIN87_RS08060 ENOG4107QHF type ii secretion system protein e HIN87_RS08070 ENOG4107EJC Preprotein translocase subunit SecG HIN87_RS08095 ENOG4105CHV Transcription elongation factor NusA HIN87_RS08110 ENOG4105KJM monovalent cation h antiporter subunit g HIN87_RS08115 ENOG4105W4C monovalent cation H antiporter subunit F HIN87_RS08120 ENOG4105SC1 monovalent cation H antiporter subunit E HIN87_RS08125 ENOG4107R4Z monovalent cation h antiporter subunit d HIN87_RS08130 ENOG4108ZE9 Monovalent cation H antiporter subunit C HIN87_RS08135 ENOG4105D65 subunit l HIN87_RS08150 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase HIN87_RS08155 ENOG41061H0 Monooxygenase HIN87_RS08170 ENOG4105DDZ Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity) HIN87_RS08180 ENOG4105CSR polyphosphate kinase 2 HIN87_RS08190 ENOG4105DSY exodeoxyribonuclease V, gamma HIN87_RS08195 ENOG4107QKA exodeoxyribonuclease V beta HIN87_RS08200 ENOG4107QYX exodeoxyribonuclease v alpha HIN87_RS08220 ENOG4107QUT magnesium and cobalt transport protein CorA HIN87_RS08225 ENOG4108ZKH Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ (By similarity) HIN87_RS08230 ENOG4105DVC DnaJ domain protein HIN87_RS08245 ENOG4105CKD glutathione-regulated potassium-efflux system protein HIN87_RS08250 ENOG4105C25 Primosomal protein n' HIN87_RS08255 ENOG4105D7Q type ii secretion system HIN87_RS08260 ENOG4108VAU general secretion pathway protein G HIN87_RS08270 ENOG4108Z7R Chaperone CsaA HIN87_RS08275 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) HIN87_RS08280 ENOG4108JU5 Magnesium and cobalt efflux protein HIN87_RS08285 ENOG41082K8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity) HIN87_RS08295 ENOG4105DWH electron transfer flavoprotein-ubiquinone oxidoreductase HIN87_RS08305 ENOG4105F03 Provides the (R)-glutamate required for cell wall biosynthesis (By similarity) HIN87_RS08320 ENOG4105C5X domain protein HIN87_RS08325 ENOG4108BEW Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity) HIN87_RS08335 ENOG4105BZ8 glutamate synthase HIN87_RS08365 ENOG4107T8P acyl-Coa dehydrogenase HIN87_RS08375 ENOG4107QI1 Mate efflux family protein HIN87_RS08385 ENOG4105CSA Coproporphyrinogen iii oxidase HIN87_RS08390 ENOG4105EMU Dehydrogenase HIN87_RS08395 ENOG4105CBN LysR family transcriptional regulator HIN87_RS08410 ENOG4105J5T Amp-dependent synthetase and ligase HIN87_RS08415 ENOG4105C03 ribonuclease HIN87_RS08425 ENOG4105EI2 Pseudouridine synthase HIN87_RS08430 ENOG4107XGZ Hydrolase HIN87_RS08435 ENOG4105D29 Helix-turn-helix type 11 domain protein HIN87_RS08450 ENOG4108W5M transcriptional regulator HIN87_RS08465 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase HIN87_RS08480 ENOG4105DUM transcriptional regulator, lysR family HIN87_RS08505 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HIN87_RS08560 ENOG4105CK2 sodium dicarboxylate symporter HIN87_RS08570 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase HIN87_RS08575 ENOG4105N14 lysine exporter protein LysE YggA HIN87_RS08585 ENOG4105C5H ABC transporter HIN87_RS08600 ENOG4105KVH Transcriptional regulator HIN87_RS08610 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) HIN87_RS08625 ENOG4105C4R Atp-dependent dna helicase HIN87_RS08630 ENOG4105VFU Rna-binding protein HIN87_RS08650 ENOG4105CKD glutathione-regulated potassium-efflux system protein HIN87_RS08665 ENOG4107RGH Aldehyde dehydrogenase HIN87_RS08675 ENOG4105CIY formyltetrahydrofolate deformylase HIN87_RS08775 ENOG4105DWV Homoserine O-trans-acetylase HIN87_RS08785 ENOG4105CYQ Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity) HIN87_RS08795 ENOG4108ESX Receptor HIN87_RS08805 ENOG4105CCQ Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity) HIN87_RS08825 ENOG4107GFK fumarate HIN87_RS08830 ENOG4108DNC Involved in acetate metabolism (By similarity) HIN87_RS08835 ENOG4105C6H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity) HIN87_RS08840 ENOG4105C01 Dihydroxy-acid dehydratase HIN87_RS08845 ENOG4108UHU Aldolase HIN87_RS08850 ENOG4105C6Z Gluconate HIN87_RS08855 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family HIN87_RS08860 ENOG4105C26 Dehydrogenase HIN87_RS08870 ENOG4106HB6 Alpha beta hydrolase HIN87_RS08885 ENOG4105CN1 protease HIN87_RS08900 ENOG4105WVQ Fe-S assembly protein IscX HIN87_RS08920 ENOG4105HSZ Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity) HIN87_RS08940 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) HIN87_RS08960 ENOG4105VW4 glutaredoxin 3 HIN87_RS08970 ENOG4105E06 May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity) HIN87_RS08975 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) HIN87_RS08985 ENOG4105CSJ Enoyl- acyl-carrier-protein reductase NADH HIN87_RS08990 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HIN87_RS08995 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) HIN87_RS09000 ENOG4105DJY efflux transporter, rnd family, mfp subunit HIN87_RS09025 ENOG4105C7K acetolactate synthase HIN87_RS09030 ENOG4108ZP8 Acetolactate synthase small subunit HIN87_RS09040 ENOG4105BZU Histidine kinase HIN87_RS09060 ENOG4105C8A Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity) HIN87_RS09075 ENOG4105F8V Hydrolase, tatD family HIN87_RS09080 ENOG4107QM5 aconitate hydratase HIN87_RS09090 ENOG4105CUZ uba thif-type nad fad binding protein HIN87_RS09100 ENOG4107RSM transcriptional regulator HIN87_RS09110 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) HIN87_RS09125 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) HIN87_RS09130 ENOG4107RRE RNA-directed DNA polymerase HIN87_RS09145 ENOG4106UX7 integral membrane protein HIN87_RS09150 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HIN87_RS09155 ENOG4105W8H transhydrogenase (subunit alpha HIN87_RS09160 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) HIN87_RS09175 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) HIN87_RS09180 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HIN87_RS09185 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase HIN87_RS09190 ENOG4105BZU Histidine kinase HIN87_RS09195 ENOG4105C6T cysteine synthase HIN87_RS09210 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) HIN87_RS09220 ENOG4105DXN mazG family HIN87_RS09225 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein HIN87_RS09230 ENOG4105DJ0 Poly(A) Polymerase HIN87_RS09235 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase HIN87_RS09255 ENOG41080Z8 PHOSPHOCARRIER protein HIN87_RS09260 ENOG4105N42 UPF0307 protein HIN87_RS09265 ENOG4105CEY Amp-dependent synthetase and ligase HIN87_RS09280 ENOG4105CYM Glutathione S-transferase HIN87_RS09285 ENOG4105W39 Membrane HIN87_RS09325 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) HIN87_RS09345 ENOG4105C4P Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity) HIN87_RS09355 ENOG4105C9X ppx gppa phosphatase HIN87_RS09365 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) HIN87_RS09370 ENOG4105II7 pyrroline-5-carboxylate reductase HIN87_RS09375 ENOG4108VIA integral membrane protein HIN87_RS09380 ENOG4105C2M dna polymerase I HIN87_RS09400 ENOG4107QHF type ii secretion system protein e HIN87_RS09405 ENOG4108ZHJ Organic hydroperoxide resistance protein HIN87_RS09410 ENOG4105K56 Transcriptional regulator HIN87_RS09480 ENOG4105CDF Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity) HIN87_RS09485 ENOG4105E21 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity) HIN87_RS09490 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) HIN87_RS09545 ENOG4108Z0R Transferase HIN87_RS09550 ENOG41072GX Peptidase M22 Glycoprotease HIN87_RS09575 ENOG4105DJV ribulose-phosphate 3-epimerase HIN87_RS09580 ENOG4108HCJ Hydrolase HIN87_RS09590 ENOG4105E3B Multicopper oxidase HIN87_RS09610 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) HIN87_RS09615 ENOG4105C5V Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity) HIN87_RS09620 ENOG4105D0I Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity) HIN87_RS09655 ENOG4105ETT transcriptional Regulator, LysR family HIN87_RS09660 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS09665 ENOG4107RGD Major Facilitator superfamily HIN87_RS09670 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HIN87_RS09690 ENOG4107EFR Flavocytochrome c HIN87_RS09695 ENOG4106P55 Transcriptional regulator HIN87_RS09710 ENOG4106P55 Transcriptional regulator HIN87_RS09720 ENOG4105CH2 amidohydrolase HIN87_RS09745 ENOG4107YAQ Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity) HIN87_RS09750 ENOG41082JN Transcriptional regulator HIN87_RS09845 ENOG4105EZY Pyrroloquinoline quinone biosynthesis protein E HIN87_RS09860 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HIN87_RS09870 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) HIN87_RS09880 ENOG4107EXC regulatoR HIN87_RS09885 ENOG4105E0F Histidine kinase HIN87_RS09895 ENOG4105BZU Histidine kinase HIN87_RS09915 ENOG4105GKE subunit e HIN87_RS09920 ENOG4107QIZ NADH dehydrogenase HIN87_RS09925 ENOG4108IEH NADH dehydrogenase subunit g HIN87_RS09940 ENOG4107UFS subunit j HIN87_RS09950 ENOG4105D65 subunit l HIN87_RS09955 ENOG4105C8S subunit m HIN87_RS09975 ENOG4105DUM transcriptional regulator, lysR family HIN87_RS09980 ENOG4105DP0 ferredoxin-NADP reductase HIN87_RS10005 ENOG4105CBX hi0933 family HIN87_RS10010 ENOG4105K6H D-cysteine desulfhydrase HIN87_RS10040 ENOG4105CKH Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity) HIN87_RS10050 ENOG4105D1F ATP-binding protein HIN87_RS10100 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) HIN87_RS10110 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY HIN87_RS10125 ENOG4105HF0 Membrane HIN87_RS10135 ENOG4105CDB Required for chromosome condensation and partitioning (By similarity) HIN87_RS10155 ENOG4106UW1 Major Facilitator superfamily HIN87_RS10160 ENOG4105C1K alpha-alpha-trehalose-phosphate synthase HIN87_RS10165 ENOG4108K4C ec 3.1.3.12 HIN87_RS10170 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HIN87_RS10180 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) HIN87_RS10185 ENOG41090JN Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) HIN87_RS10195 ENOG4105FE9 pseudouridine synthase HIN87_RS10200 ENOG4105K8I Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity) HIN87_RS10205 ENOG4108KVX Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity) HIN87_RS10210 ENOG4107RTD sua5 ycio yrdc ywlc family protein HIN87_RS10215 ENOG4108BPE -transporting atpase HIN87_RS10220 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein HIN87_RS10230 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HIN87_RS10235 ENOG4105CHR reductase HIN87_RS10245 ENOG4109066 lysm domain bon superfamily protein HIN87_RS10250 ENOG4105DWF phosphomethylpyrimidine kinase HIN87_RS10260 ENOG4105C66 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity) HIN87_RS10290 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HIN87_RS10320 ENOG4105C1U Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity) HIN87_RS10335 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) HIN87_RS10340 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HIN87_RS10345 ENOG4105C34 Pseudouridine synthase HIN87_RS10350 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase HIN87_RS10660 ENOG4105DFP Integrase HIN87_RS10670 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HIN87_RS10690 ENOG4105EJC lysr family transcriptional regulator HIN87_RS10695 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) HIN87_RS10700 ENOG4105C94 Transporter HIN87_RS10710 ENOG4105DVW rieske (2Fe-2S) HIN87_RS10715 ENOG4105C26 Dehydrogenase HIN87_RS10720 ENOG4105E3J oxidoreductase HIN87_RS10735 ENOG4105C4K Nad synthetase HIN87_RS10745 ENOG4105EUB pirin domain protein HIN87_RS10750 ENOG4108YXA Membrane HIN87_RS10795 ENOG4105KEG ribosomal-protein-alanine acetyltransferase HIN87_RS10805 ENOG4108R4Z Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity) HIN87_RS10810 ENOG4105C3M thioredoxin reductase HIN87_RS10815 ENOG4105CNU cell division protein FtsK HIN87_RS10820 ENOG4105CCF Lysine exporter protein (Lyse ygga) HIN87_RS10835 ENOG4107QMS site-determining protein HIN87_RS10850 ENOG4106HNH Acyl-transferase HIN87_RS10855 ENOG4108ZG0 Ompa motb domain protein HIN87_RS10860 ENOG4105C4R Atp-dependent dna helicase HIN87_RS10870 ENOG4107QKV phosphomannomutase HIN87_RS10885 ENOG4105E7A Glutamine amidotransferase HIN87_RS10910 ENOG41090R7 Ferric uptake HIN87_RS10915 ENOG4105CZX twitching motility protein HIN87_RS10920 ENOG4105CZX twitching motility protein HIN87_RS10925 ENOG4105DFA alanine racemase domain protein HIN87_RS10930 ENOG4105EYH Exonuclease HIN87_RS10935 ENOG4107RH8 nuclease SbcCD subunit D HIN87_RS10955 ENOG4105ECP epimerase HIN87_RS10960 ENOG4105MWK D-amino acid dehydrogenase, small subunit HIN87_RS10965 ENOG4105D52 delta-aminolevulinic acid dehydratase HIN87_RS10970 ENOG4108VUY thioesterase Superfamily protein HIN87_RS10975 ENOG4105CW7 secretion protein, HlyD family HIN87_RS10980 ENOG4105C0R drug resistance transporter emrb qaca subfamily HIN87_RS10985 ENOG4105CFB Gamma-glutamyltranspeptidase (EC 2.3.2.2) HIN87_RS11055 ENOG41083X2 DNA polymerase III, epsilon subunit HIN87_RS11215 ENOG4105VTN Protein of unknown function (DUF1311) HIN87_RS11390 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HIN87_RS11460 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HIN87_RS11525 ENOG4105C54 Major Facilitator superfamily HIN87_RS11530 ENOG4105CDP Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity) HIN87_RS11555 ENOG4105D5Q Arginine ornithine antiporter HIN87_RS11585 ENOG4108MHR Repressor involved in choline regulation of the bet genes (By similarity) HIN87_RS11590 ENOG4105C94 Transporter HIN87_RS11595 ENOG4105C94 Transporter HIN87_RS11605 ENOG4108S4H thioesterase Superfamily protein HIN87_RS11615 ENOG4105CKI cobalamin synthesis protein HIN87_RS11625 ENOG4108VWS Yaeq family HIN87_RS11635 ENOG4107BJW polysaccharide deacetylase HIN87_RS11640 ENOG4105CND Glycosyl transferase, family 2 HIN87_RS11650 ENOG4106YT9 Enoyl-CoA hydratase HIN87_RS11665 ENOG41069M3 Transcriptional regulator HIN87_RS11685 ENOG4105CHR reductase HIN87_RS11700 ENOG4105DJB Major Facilitator Superfamily HIN87_RS11710 ENOG4108MXF Alpha Beta Hydrolase HIN87_RS11715 ENOG4105CHR reductase HIN87_RS11730 ENOG4105C7K acetolactate synthase HIN87_RS11740 ENOG4105CSH Transporter HIN87_RS11745 ENOG4108RBJ Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity) HIN87_RS11750 ENOG4105CSV Glutaminase HIN87_RS11755 ENOG4108R6W Transcriptional regulator, ARAC family HIN87_RS11760 ENOG4105EU0 Major facilitator Superfamily HIN87_RS11765 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) HIN87_RS11775 ENOG4108PZW LysR family Transcriptional regulator HIN87_RS11785 ENOG4105CSP Major Facilitator Superfamily HIN87_RS11805 ENOG4105C3R Methionine synthase HIN87_RS11810 ENOG4105CJ3 phosphate transporter HIN87_RS11830 ENOG4105E6M Sulphatase-modifying factor protein HIN87_RS11835 ENOG4107QRH Arylsulfatase (Ec 3.1.6.1) HIN87_RS11850 ENOG4107RNH Outer membrane receptor FepA HIN87_RS11870 ENOG4108UJV acyl-CoA thioesterase i HIN87_RS11875 ENOG4108I0Y (ABC) transporter HIN87_RS11880 ENOG4105CV6 ABC transporter, permease HIN87_RS11885 ENOG4107U91 Rhomboid family HIN87_RS11910 ENOG4105C5Q Transcriptional regulator HIN87_RS11920 ENOG4107QZF nitrite reductase NADPH large subunit HIN87_RS11925 ENOG4105VCQ rubredoxin HIN87_RS11945 ENOG4108MRJ HIN87_RS11960 ENOG4105C3T may be the GTPase, regulating ATP sulfurylase activity (By similarity) HIN87_RS11975 ENOG4105D4T Citrate transporter HIN87_RS11980 ENOG4105C37 (CBS) domain HIN87_RS11990 ENOG4107RET Isocitrate lyase HIN87_RS12020 ENOG4105CQM Urea amidohydrolase subunit alpha HIN87_RS12030 ENOG4108WKG Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity) HIN87_RS12045 ENOG4106H78 methyltransferase HIN87_RS12050 ENOG4105CJN penicillin-binding protein HIN87_RS12075 ENOG4105CSM endonuclease III HIN87_RS12080 ENOG4108R3D Electron transport complex HIN87_RS12085 ENOG4105D82 Glutamate dehydrogenase HIN87_RS12095 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b HIN87_RS12115 ENOG4105UYK outer membrane protein a HIN87_RS12130 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase HIN87_RS12195 ENOG4105RDA repressor HIN87_RS12525 ENOG4107RAQ aminopeptidase HIN87_RS12530 ENOG4105D0A hydroxylase HIN87_RS12535 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family HIN87_RS12555 ENOG4108ZUB Lysine exporter protein (Lyse ygga) HIN87_RS12560 ENOG4105CXD Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity) HIN87_RS12570 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) HIN87_RS12580 ENOG4105W4M Transport-associated protein HIN87_RS12590 ENOG4105E09 nadh pyrophosphatase HIN87_RS12600 ENOG4107RZZ dna polymerase iii epsilon subunit HIN87_RS12605 ENOG4105E9H Lytic Murein transglycosylase HIN87_RS12605 ENOG4105E9H Lytic Murein transglycosylase HIN87_RS12615 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component HIN87_RS12620 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component HIN87_RS12625 ENOG4108JQ5 ABC transporter HIN87_RS12660 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) HIN87_RS12680 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HIN87_RS12690 ENOG4105D01 (LipO)protein HIN87_RS12710 ENOG4105CNA YD repeat protein HIN87_RS12760 ENOG4105C85 amino acid HIN87_RS12770 ENOG4105CUB amino acid HIN87_RS12790 ENOG4105C26 Dehydrogenase HIN87_RS12810 ENOG4105C85 amino acid HIN87_RS12815 ENOG4107RGH Aldehyde dehydrogenase HIN87_RS12820 ENOG4108ZX5 transcriptional regulator HIN87_RS12825 ENOG4105DJP Membrane HIN87_RS12830 ENOG4105CTX dehydratase HIN87_RS12835 ENOG4105DJB Major Facilitator Superfamily HIN87_RS12840 ENOG4105EQX glucarate dehydratase HIN87_RS12850 ENOG4105CZJ Aldehyde dehydrogenase HIN87_RS12855 ENOG4105JXH GntR family transcriptional regulator HIN87_RS12870 ENOG4105NI3 Protein of unknown function (DUF3237) HIN87_RS12875 ENOG4105EPF Outer membrane porin HIN87_RS12880 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS12895 ENOG4108D7R p-hydroxycinnamoyl CoA hydratase lyase HIN87_RS12900 ENOG4108SC4 )-transporter HIN87_RS12915 ENOG4105E3J oxidoreductase HIN87_RS12925 ENOG4105D2S major facilitator superfamily HIN87_RS12930 ENOG4105EPF Outer membrane porin HIN87_RS12950 ENOG4107RN6 Monooxygenase HIN87_RS12960 ENOG4105JQZ Methyltransferase HIN87_RS12965 ENOG4105F95 Monooxygenase HIN87_RS13000 ENOG4105F95 Monooxygenase HIN87_RS13010 ENOG4105C7N Xanthine uracil vitamin C permease HIN87_RS13015 ENOG4105EKD Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity) HIN87_RS13020 ENOG4105CPW cytochrome b561 HIN87_RS13030 ENOG4108UH2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity) HIN87_RS13040 ENOG4105CFH Aspartokinase HIN87_RS13050 ENOG4105C17 glyceraldehyde-3-phosphate dehydrogenase HIN87_RS13060 ENOG4105C91 Plays an important role in the de novo pathway of purine nucleotide biosynthesis HIN87_RS13075 ENOG4105CPC Aldo Keto reductase HIN87_RS13080 ENOG4107RYR Transcriptional regulator, Crp Fnr family HIN87_RS13085 ENOG4108UKZ OsmC family HIN87_RS13100 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HIN87_RS13130 ENOG4105CD3 dihydroorotase HIN87_RS13135 ENOG4108ZG0 Ompa motb domain protein HIN87_RS13145 ENOG4108TGY Glutathione S-transferase HIN87_RS13150 ENOG4105CZ1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity) HIN87_RS13160 ENOG4108K3A Glutathione S-transferase HIN87_RS13170 ENOG4108JU3 Alkyl hydroperoxide reductase HIN87_RS13180 ENOG4105E26 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity) HIN87_RS13190 ENOG4105D3R alkyl hydroperoxide reductase HIN87_RS13195 ENOG4105CQ7 ATP-dependent helicase HIN87_RS13210 ENOG4105D2S major facilitator superfamily HIN87_RS13215 ENOG4105DKK Benzoate HIN87_RS13220 ENOG4107SEV 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase HIN87_RS13225 ENOG4108JA0 Oxidoreductase, FAD NAD(P)-binding domain protein HIN87_RS13230 ENOG4108UKV benzoate 1,2-dioxygenase HIN87_RS13235 ENOG4105FUY alpha subunit HIN87_RS13240 ENOG4108KB2 LysR family Transcriptional regulator HIN87_RS13290 ENOG4107SVC Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity) HIN87_RS13325 ENOG410829K Lysine exporter protein (Lyse ygga) HIN87_RS13330 ENOG4105VEQ Cold shock protein HIN87_RS13340 ENOG4105II7 pyrroline-5-carboxylate reductase HIN87_RS13410 ENOG4105C2X Arabinose 5-phosphate isomerase HIN87_RS13425 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA HIN87_RS13430 ENOG4108IUZ ABC transporter HIN87_RS13440 ENOG4105DFG type I secretion outer membrane protein HIN87_RS13480 ENOG4108Z4U Ferredoxin HIN87_RS13500 ENOG4107AQZ Membrane HIN87_RS13505 ENOG4105BZU Histidine kinase HIN87_RS13510 ENOG4105D1S lipid A biosynthesis HIN87_RS13520 ENOG4105D2S major facilitator superfamily HIN87_RS13540 ENOG4105F35 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity) HIN87_RS13570 ENOG4105CNA YD repeat protein HIN87_RS13600 ENOG4108WAV Transcriptional regulator HIN87_RS13605 ENOG4105C5A transporter HIN87_RS13625 ENOG4108JIK carboxylase HIN87_RS13630 ENOG4107R4J Chloride channel HIN87_RS13635 ENOG4105D5K Hemolysin activator protein HIN87_RS13640 ENOG4105CKT filamentous hemagglutinin HIN87_RS13680 ENOG4105CF7 AraC family transcriptional regulator HIN87_RS13695 ENOG4105C04 l-carnitine dehydratase bile acid-inducible protein F HIN87_RS13700 ENOG4105CBH Hydroxymethylglutaryl-CoA lyase HIN87_RS13705 ENOG4105CSP Major Facilitator Superfamily HIN87_RS13710 ENOG4107VGR Catalase HIN87_RS13715 ENOG4105CPW cytochrome b561 HIN87_RS13720 ENOG4105HEI LysR family (Transcriptional regulator HIN87_RS13730 ENOG4107HP6 Transcriptional regulator HIN87_RS13735 ENOG41072AC 4-hydroxybenzoate 3-monooxygenase HIN87_RS13745 ENOG4105C4Y ABC transporter HIN87_RS13750 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) HIN87_RS13755 ENOG4107RCV ABC transporter, permease HIN87_RS13765 ENOG4107STF Involved in phosphonate degradation (By similarity) HIN87_RS13770 ENOG4108KAZ Involved in phosphonate degradation (By similarity) HIN87_RS13775 ENOG4107RGD Major Facilitator superfamily HIN87_RS13780 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS13795 ENOG4108UKI Enoyl-CoA hydratase HIN87_RS13800 ENOG4105EA8 2-Nitropropane dioxygenase HIN87_RS13805 ENOG4105EQ0 Major Facilitator superfamily HIN87_RS13815 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS13820 ENOG4105DYT 3-hydroxyacyl-CoA dehydrogenase HIN87_RS13825 ENOG4105CHR reductase HIN87_RS13830 ENOG4105E39 Enoyl-CoA hydratase HIN87_RS13835 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS13840 ENOG4107RGD Major Facilitator superfamily HIN87_RS13845 ENOG4107QP7 CoA-transferase subunit A HIN87_RS13850 ENOG4107QNJ CoA-transferase subunit B HIN87_RS13870 ENOG4105CSU acyl-Coa dehydrogenase HIN87_RS13885 ENOG4105CC0 LysR family Transcriptional regulator HIN87_RS13900 ENOG4105E39 Enoyl-CoA hydratase HIN87_RS13905 ENOG4107QX3 carboxylase HIN87_RS13910 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS13915 ENOG4105R8C Transcriptional regulator HIN87_RS13920 ENOG4105CEY Amp-dependent synthetase and ligase HIN87_RS13940 ENOG4105HEI LysR family (Transcriptional regulator HIN87_RS13990 ENOG4105CYX Short-chain dehydrogenase reductase Sdr HIN87_RS14010 ENOG4105KT5 UmuD protein HIN87_RS14020 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS14030 ENOG4105BZU Histidine kinase HIN87_RS14035 ENOG4105DW3 Response regulator receiver modulated metal dependent phosphohydrolase HIN87_RS14050 ENOG4105EAD ABC transporter HIN87_RS14055 ENOG4108HW4 amino acid AbC transporter HIN87_RS14060 ENOG4105CDA abc transporter atp-binding protein HIN87_RS14065 ENOG4107RP9 extracellular solute-binding protein, family 3 HIN87_RS14070 ENOG4105CT1 (ABC) transporter HIN87_RS14075 ENOG4105EXG Transcriptional regulator HIN87_RS14080 ENOG4105CCF Lysine exporter protein (Lyse ygga) HIN87_RS14085 ENOG4105C9B Cysteine desulfurase HIN87_RS14090 ENOG4105ESN nucleotide-binding protein HIN87_RS14095 ENOG4105D7W serine acetyltransferase HIN87_RS14105 ENOG4105CHR reductase HIN87_RS14110 ENOG4105CBN LysR family transcriptional regulator HIN87_RS14115 ENOG4105CYM Glutathione S-transferase HIN87_RS14120 ENOG4108SHQ Glutathione S-transferase HIN87_RS14125 ENOG4105CMU LysR family (Transcriptional regulator HIN87_RS14130 ENOG4105VAW lrga family HIN87_RS14135 ENOG41067MG lrgb family HIN87_RS14155 ENOG4105DXI Major Facilitator superfamily HIN87_RS14165 ENOG4105ETT transcriptional Regulator, LysR family HIN87_RS14175 ENOG4108K6F triphosphoribosyl-dephospho-CoA synthase HIN87_RS14180 ENOG4105WSE Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity) HIN87_RS14200 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase HIN87_RS14215 ENOG4108K70 Transcriptional regulator HIN87_RS14220 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HIN87_RS14230 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HIN87_RS14235 ENOG4105C4M (Ubiquinol oxidase) subunit I HIN87_RS14255 ENOG4105C54 Major Facilitator superfamily HIN87_RS14265 ENOG4106FTQ Taurine ABC transporter, periplasmic HIN87_RS14270 ENOG4108IY8 ABC, transporter HIN87_RS14275 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component HIN87_RS14300 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease HIN87_RS14310 ENOG4105CBN LysR family transcriptional regulator HIN87_RS14320 ENOG4105CPN adenine deaminase HIN87_RS14335 ENOG41082YX Transcriptional regulator, arsr family HIN87_RS14340 ENOG4105D6J arsenicaL-resistance protein HIN87_RS14345 ENOG4108KB2 LysR family Transcriptional regulator HIN87_RS14360 ENOG4108JU3 Alkyl hydroperoxide reductase HIN87_RS14385 ENOG4105C0B DNA polymerase III (alpha subunit) HIN87_RS14400 ENOG4105CHM Aminotransferase HIN87_RS14410 ENOG4108V06 Glutathione peroxidase HIN87_RS14415 ENOG4105E7U AraC family transcriptional regulator HIN87_RS14445 ENOG4105ZED uncharacterized protein ygaH HIN87_RS14450 ENOG4108UMN azlc family HIN87_RS14475 ENOG4105C3G gtp-binding protein HIN87_RS14480 ENOG4108UMI ABC transporter, permease HIN87_RS14490 ENOG4105D01 (LipO)protein HIN87_RS14495 ENOG4105D01 (LipO)protein HIN87_RS14510 ENOG4107T8P acyl-Coa dehydrogenase HIN87_RS14525 ENOG4105EAD ABC transporter HIN87_RS14530 ENOG4105DRP amino acid AbC transporter HIN87_RS14535 ENOG4105CDA abc transporter atp-binding protein HIN87_RS14545 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS14560 ENOG41067SE Tetr family transcriptional regulator HIN87_RS14580 ENOG4105CC0 LysR family Transcriptional regulator HIN87_RS14590 ENOG4105ETS cytosine purines uracil thiamine allantoin HIN87_RS14600 ENOG4108IPJ Membrane HIN87_RS14625 ENOG4105GQR Chaperone HIN87_RS14630 ENOG4105X0I Fimbrial HIN87_RS14650 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) HIN87_RS14675 ENOG4108HWY Beta-lactamase HIN87_RS14700 ENOG4105CV1 Transketolase (EC 2.2.1.1) HIN87_RS14710 ENOG4108YYC ycei family HIN87_RS14720 ENOG4108T58 Mg2 transport protein CorA HIN87_RS14735 ENOG4105YGK Pfam:UPF0157 HIN87_RS14740 ENOG4105C26 Dehydrogenase HIN87_RS14745 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS14750 ENOG4105CK7 Sodium proline symporter HIN87_RS14755 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) HIN87_RS14765 ENOG4108ZX5 transcriptional regulator HIN87_RS14775 ENOG4105BZ1 (ABC) transporter HIN87_RS14780 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme HIN87_RS14785 ENOG4105XPP Protein of unknown function (DUF1275) HIN87_RS14795 ENOG41080HT Transcriptional regulator, arsr family HIN87_RS14805 ENOG4105EZE Cupin 4 family protein HIN87_RS14810 ENOG4108UHJ MAF-like protein HIN87_RS14830 ENOG4105D2N Aldolase HIN87_RS14835 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HIN87_RS14840 ENOG4105E7H involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity) HIN87_RS14845 ENOG4105EHM Aminoglycoside phosphotransferase HIN87_RS14850 ENOG4108S0S Nucleotidyl transferase HIN87_RS14860 ENOG4107QJE Chromosome Partitioning Protein HIN87_RS14865 ENOG4105FA0 parb-like partition protein HIN87_RS14880 ENOG4105BZ1 (ABC) transporter HIN87_RS14885 ENOG4105CHD Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity) HIN87_RS14895 ENOG4107QRG dna polymerase iii HIN87_RS14905 ENOG4105F8V Hydrolase, tatD family HIN87_RS14930 ENOG4108RTD type II secretion system protein K HIN87_RS14950 ENOG4108Z6B deaminase HIN87_RS14965 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) HIN87_RS14970 ENOG41080YA This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) HIN87_RS14990 ENOG4107RN6 Monooxygenase HIN87_RS15000 ENOG4105D6Z AFG1 family ATPase HIN87_RS15030 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) HIN87_RS15035 ENOG4105C4R Atp-dependent dna helicase HIN87_RS15045 ENOG4108NF7 phage-type endonuclease HIN87_RS15245 ENOG4107QP3 malate synthase g HIN87_RS15255 ENOG4105SG9 biopolymer transport protein, ExbD HIN87_RS15290 ENOG4105DGW oligopeptidase A HIN87_RS15300 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component HIN87_RS15320 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase HIN87_RS15335 ENOG4105K4T epimerase HIN87_RS15340 ENOG4108YYX Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity) HIN87_RS15360 ENOG4108JA2 transcriptioN-repair coupling factor HIN87_RS15370 ENOG4105F8J Adenylate Guanylate cyclase HIN87_RS15375 ENOG4108ZIT Ferredoxin, 2FE-2S HIN87_RS15390 ENOG4108Z4V iron-sulfur cluster assembly HIN87_RS15395 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins HIN87_RS15405 ENOG4108ZF1 Transcriptional regulator, BadM Rrf2 family HIN87_RS15420 ENOG4105K70 DNA-binding protein HIN87_RS15425 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) HIN87_RS15430 ENOG4105E7U AraC family transcriptional regulator HIN87_RS15435 ENOG4105EEF Alkane 1-monooxygenase HIN87_RS15440 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS15445 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS15460 ENOG4108Z66 YbaK ebsC protein HIN87_RS15475 ENOG4105C0R drug resistance transporter emrb qaca subfamily HIN87_RS15480 ENOG4105DUU IucA IucC family protein HIN87_RS15485 ENOG4105DJU Siderophore biosynthesis protein HIN87_RS15495 ENOG4105JSC dimethylmenaquinone methyltransferase HIN87_RS15535 ENOG4108YZT Adenosylcobinamide kinase HIN87_RS15540 ENOG4105CUP Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity) HIN87_RS15545 ENOG4107TB6 phosphoglycerate mutase HIN87_RS15560 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HIN87_RS15565 ENOG4107TSN permease HIN87_RS15585 ENOG4105CNM Receptor HIN87_RS15590 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HIN87_RS15605 ENOG4105CJ1 ABC, transporter HIN87_RS15610 ENOG4107QWP ABC-2 type transporter HIN87_RS15615 ENOG4107QWP ABC-2 type transporter HIN87_RS15640 ENOG4105K59 histidine triad (HIT) protein HIN87_RS15670 ENOG4105F2W methyltransferase HIN87_RS15680 ENOG4105C28 cystathionine HIN87_RS15695 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) HIN87_RS15740 ENOG4105CG0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity) HIN87_RS15745 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) HIN87_RS15755 ENOG4105BZU Histidine kinase HIN87_RS15770 ENOG4105C0G Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity) HIN87_RS15775 ENOG4107R0V Pyruvate dehydrogenase HIN87_RS15780 ENOG4105CPP Dehydrogenase, E1 component HIN87_RS15795 ENOG4105CHR reductase HIN87_RS15805 ENOG4105FFC UPF0187 protein HIN87_RS15815 ENOG4107S76 domain protein HIN87_RS15825 ENOG4108VCT Sulfite exporter TauE/SafE HIN87_RS15840 ENOG4105UEI Transcriptional Regulator AraC Family HIN87_RS15845 ENOG4105KVH Transcriptional regulator HIN87_RS15850 ENOG4108V3G Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity) HIN87_RS15875 ENOG4106FTQ Taurine ABC transporter, periplasmic HIN87_RS15880 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HIN87_RS15900 ENOG4105CSH Transporter HIN87_RS15910 ENOG4108IJ0 Aspartate ammonia-lyase HIN87_RS15925 ENOG4107YNJ LysR family Transcriptional regulator HIN87_RS15935 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS15940 ENOG4105CRW Short chain fatty acid transporter HIN87_RS15955 ENOG4108M0I Transcriptional regulator HIN87_RS15975 ENOG4108IND Tetr family transcriptional regulator HIN87_RS15985 ENOG4105CY2 Citrate transporter HIN87_RS15990 ENOG4105DTD Dehydrogenase HIN87_RS15995 ENOG4105CF7 AraC family transcriptional regulator HIN87_RS16000 ENOG4105D2S major facilitator superfamily HIN87_RS16010 ENOG4105CHR reductase HIN87_RS16035 ENOG4105F57 Anthranilate dioxygenase reductase HIN87_RS16040 ENOG4108YS2 small subunit HIN87_RS16045 ENOG4108Q89 anthranilate 1,2-dioxygenase large subunit HIN87_RS16050 ENOG4105F4R Transcriptional regulator mode HIN87_RS16055 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein HIN87_RS16060 ENOG4105E0C molybdate abc transporter HIN87_RS16065 ENOG4105CGB Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity) HIN87_RS16070 ENOG4105X17 23-dihydro-2,3-dihydroxybenzoate dehydrogenase HIN87_RS16075 ENOG4105WQI isochorismatase HIN87_RS16085 ENOG4107T31 5'-nucleotidase HIN87_RS16120 ENOG4108IGT Dipeptidase HIN87_RS16140 ENOG4107RZC phospholipase d HIN87_RS16190 ENOG4105X0I Fimbrial HIN87_RS16425 ENOG4105BZS acriflavin resistance protein HIN87_RS16430 ENOG4105C1P efflux transporter, rnd family, mfp subunit HIN87_RS16435 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HIN87_RS16440 ENOG4105E0F Histidine kinase HIN87_RS16445 ENOG4108821 RND type efflux pump HIN87_RS16450 ENOG4108R6W Transcriptional regulator, ARAC family HIN87_RS16465 ENOG4108BAS reductase HIN87_RS16515 ENOG4105CV2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity) HIN87_RS16565 ENOG4105C5T Phosphoribosyl pyrophosphate synthase HIN87_RS16585 ENOG4105E0A ABC, transporter HIN87_RS16590 ENOG4105EHG Permease protein HIN87_RS16600 ENOG4105DQ4 alcohol dehydrogenase HIN87_RS16615 ENOG4105CF7 AraC family transcriptional regulator HIN87_RS16620 ENOG4105CF3 3-Hydroxyisobutyrate dehydrogenase HIN87_RS16630 ENOG4105EXW epimerase dehydratase HIN87_RS16635 ENOG4105DDW LysR family Transcriptional regulator HIN87_RS16690 ENOG4106P55 Transcriptional regulator HIN87_RS16735 ENOG4105CKT filamentous hemagglutinin HIN87_RS16740 ENOG4105D5K Hemolysin activator protein HIN87_RS16750 ENOG4105CH2 amidohydrolase HIN87_RS16760 ENOG4105CKD glutathione-regulated potassium-efflux system protein HIN87_RS16765 ENOG4105D8V Glucose sorbosone dehydrogenase HIN87_RS16770 ENOG4105EJC lysr family transcriptional regulator HIN87_RS16775 ENOG4105CHJ isochorismatase hydrolase HIN87_RS16785 ENOG4107Z3H Transcriptional regulator, TetR family HIN87_RS16825 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HIN87_RS16840 ENOG4105CZJ Aldehyde dehydrogenase HIN87_RS16860 ENOG4107EJG GntR family transcriptional regulator HIN87_RS16870 ENOG4108KB2 LysR family Transcriptional regulator HIN87_RS16875 ENOG4105DTQ mandelate racemase muconate lactonizing HIN87_RS16880 ENOG4105NN7 muconolactone delta-isomerase HIN87_RS16890 ENOG4107QP7 CoA-transferase subunit A HIN87_RS16895 ENOG4107QNJ CoA-transferase subunit B HIN87_RS16900 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS16905 ENOG4105F2Z 3-oxoadipate enol-lactonase HIN87_RS16915 ENOG4105C26 Dehydrogenase HIN87_RS16925 ENOG4105F11 amine oxidase HIN87_RS16945 ENOG4105CHR reductase HIN87_RS16955 ENOG4105FUY alpha subunit HIN87_RS16975 ENOG4105C3P Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity) HIN87_RS16985 ENOG4105DNH Major Facilitator HIN87_RS17010 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS17015 ENOG4108PTX LysR family Transcriptional regulator HIN87_RS17020 ENOG4107HP6 Transcriptional regulator HIN87_RS17035 ENOG4105MD1 YeeE YedE family protein HIN87_RS17045 ENOG4105DZG Dehydrogenase HIN87_RS17050 ENOG4105TW1 Carbohydrate-selective porin OprB HIN87_RS17055 ENOG4106JPM 3-dehydroshikimate dehydratase HIN87_RS17060 ENOG4105FF2 Type I DHQase HIN87_RS17065 ENOG4105RM9 Protocatechuate 3,4-dioxygenase alpha HIN87_RS17070 ENOG4105EU7 Protocatechuate 3,4-dioxygenase, beta HIN87_RS17075 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase HIN87_RS17080 ENOG4105D2S major facilitator superfamily HIN87_RS17085 ENOG4105F2Z 3-oxoadipate enol-lactonase HIN87_RS17090 ENOG4107RAW 3-carboxy-cis-cis-muconate cycloisomerase HIN87_RS17095 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS17100 ENOG4107QNJ CoA-transferase subunit B HIN87_RS17105 ENOG4107QP7 CoA-transferase subunit A HIN87_RS17115 ENOG4105XX3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) HIN87_RS17120 ENOG4107VMU Membrane HIN87_RS17165 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase HIN87_RS17180 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) HIN87_RS17190 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit HIN87_RS17195 ENOG4105KAE Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity) HIN87_RS17225 ENOG4105C7B Threonine dehydratase HIN87_RS17235 ENOG4105CZN Potassium uptake protein HIN87_RS17240 ENOG4105HDD phospholipase HIN87_RS17250 ENOG4105E0K tonB-dependent siderophore receptor HIN87_RS17265 ENOG4105PV3 Inner membrane protein yqiJ HIN87_RS17275 ENOG4105C4M (Ubiquinol oxidase) subunit I HIN87_RS17280 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii HIN87_RS17300 ENOG41068P6 UPF0319 protein HIN87_RS17310 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) HIN87_RS17335 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) HIN87_RS17340 ENOG4105C8Y Acetylornithine aminotransferase HIN87_RS17345 ENOG4105M2J Glutaredoxin HIN87_RS17355 ENOG4105CC0 LysR family Transcriptional regulator HIN87_RS17360 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) HIN87_RS17365 ENOG4105CWM branched-chain amino acid transport system II carrier protein HIN87_RS17390 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) HIN87_RS17395 ENOG4105DE4 1-phosphofructokinase HIN87_RS17400 ENOG4105DM4 PTS System HIN87_RS17415 ENOG4105BZU Histidine kinase HIN87_RS17425 ENOG4105D8V Glucose sorbosone dehydrogenase HIN87_RS17430 ENOG4108RAV Conserved protein HIN87_RS17435 ENOG4105CHH sulfate transporter HIN87_RS17450 ENOG4105C85 amino acid HIN87_RS17460 ENOG4105F7P transcriptional regulator AsnC family HIN87_RS17485 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 HIN87_RS17490 ENOG4105VEJ Heat shock protein HIN87_RS17500 ENOG4105Y3E Modulates RecA activity (By similarity) HIN87_RS17515 ENOG4105DAF Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) HIN87_RS17535 ENOG4105E1Z Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane HIN87_RS17540 ENOG4105DZP Membrane-associated zinc metalloprotease HIN87_RS17550 ENOG4105KNE Phosphatidate cytidylyltransferase HIN87_RS17555 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) HIN87_RS17575 ENOG4105CUX Signal transduction histidine kinase HIN87_RS17580 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family HIN87_RS17635 ENOG4105CMR udp-glucose 4-epimerase HIN87_RS17640 ENOG4108ZAT Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity) HIN87_RS17660 ENOG4105T38 integral membrane protein HIN87_RS17665 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HIN87_RS17675 ENOG4105CVM Molybdenum cofactor synthesis domain protein HIN87_RS17680 ENOG4108YXW Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) HIN87_RS17715 ENOG4108IFG nitrite reductase, (NAD(P)H) HIN87_RS17720 ENOG4107QZF nitrite reductase NADPH large subunit HIN87_RS17730 ENOG4105CK6 Two component transcriptional regulator (Winged helix family HIN87_RS17750 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein HIN87_RS17755 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase HIN87_RS17765 ENOG4105D8G Major Facilitator superfamily HIN87_RS17895 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) HIN87_RS18065 ENOG4105VTN Protein of unknown function (DUF1311) HIN87_RS18220 ENOG41083X2 DNA polymerase III, epsilon subunit HIN87_RS18280 ENOG4105CBC glutamate synthase HIN87_RS18310 ENOG4105C0A alcohol dehydrogenase HIN87_RS18320 ENOG4105HSS phospholipase C HIN87_RS18325 ENOG4107QMP dna polymerase iii subunits gamma and tau HIN87_RS18360 ENOG4105CHR reductase HIN87_RS18365 ENOG4105CHU acetyl-coa acetyltransferase HIN87_RS18375 ENOG4105C5Q Transcriptional regulator HIN87_RS18385 ENOG4108NIW Leucine export protein LeuE HIN87_RS18390 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS18395 ENOG4105DKK Benzoate HIN87_RS18405 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic HIN87_RS18430 ENOG41081QV Universal stress protein HIN87_RS18435 ENOG4105C5H ABC transporter HIN87_RS18455 ENOG4105CNM Receptor HIN87_RS18485 ENOG4105CUY Mechanosensitive ion channel HIN87_RS18495 ENOG4105R8C Transcriptional regulator HIN87_RS18505 ENOG4105EW9 transcriptional regulator AsnC family HIN87_RS18510 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) HIN87_RS18535 ENOG4108D1K outer membrane usher protein HIN87_RS18550 ENOG4105CD8 aminopeptidase N HIN87_RS18570 ENOG4105F4I Transcriptional regulator HIN87_RS18580 ENOG4107QUV Domain protein HIN87_RS18585 ENOG4105C0A alcohol dehydrogenase HIN87_RS18595 ENOG4107RR1 TRANSCRIPTIONal HIN87_RS18605 ENOG4107R55 ethanolamine transporter HIN87_RS18610 ENOG4105CPD ethanolamine ammonia-lyase HIN87_RS18620 ENOG4105CM0 Catalyzes the synthesis of GMP from XMP (By similarity) HIN87_RS18625 ENOG4105CX6 glutaminyL-tRNA synthetase HIN87_RS18645 ENOG4108RCM Nitroreductase HIN87_RS18650 ENOG4108TZV Membrane HIN87_RS18655 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) HIN87_RS18665 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) HIN87_RS18670 ENOG4105K8N protein family UPF0079, ATPase HIN87_RS18705 ENOG4105DZ2 Transcriptional regulator HIN87_RS18720 ENOG4105F27 Major Facilitator HIN87_RS18725 ENOG4105EYW Ion transport protein HIN87_RS18735 ENOG4107QIJ Aconitate hydratase 2 HIN87_RS18750 ENOG4105CFU surface antigen HIN87_RS18755 ENOG4107S74 Lysophospholipid transporter LplT HIN87_RS18770 ENOG4105CFQ glutamine synthetase HIN87_RS18775 ENOG4105EEX Two component transcriptional regulator (Winged helix family HIN87_RS18780 ENOG4105C08 Histidine kinase HIN87_RS18785 ENOG4108R80 One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity) HIN87_RS18790 ENOG4105C8X One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) HIN87_RS18795 ENOG4105D9K One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity) HIN87_RS18815 ENOG4105D06 uba thif-type nad fad binding protein HIN87_RS18820 ENOG4108MEJ flavin reductase domain protein HIN87_RS18830 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS18845 ENOG4105GVF (ABC) transporter HIN87_RS18850 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component HIN87_RS18855 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) HIN87_RS18870 ENOG4105CC0 LysR family Transcriptional regulator HIN87_RS18885 ENOG4105DEN Luciferase family HIN87_RS18900 ENOG4105CND Glycosyl transferase, family 2 HIN87_RS18905 ENOG4107BJW polysaccharide deacetylase HIN87_RS18930 ENOG4105E2S oxidase) subunit II HIN87_RS18935 ENOG4105BZ9 Cytochrome C oxidase, subunit I HIN87_RS18940 ENOG4105CCU oxidase (Subunit III) HIN87_RS18945 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) HIN87_RS18970 ENOG4105CDU Replicative dna helicase HIN87_RS18975 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) HIN87_RS19025 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) HIN87_RS19030 ENOG4105DC1 bifunctional purine biosynthesis protein purh HIN87_RS19035 ENOG4105C12 Phosphoribosylglycinamide synthetase HIN87_RS19045 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) HIN87_RS19050 ENOG4108UMI ABC transporter, permease HIN87_RS19055 ENOG4108RW0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity) HIN87_RS19065 ENOG4105CK2 sodium dicarboxylate symporter HIN87_RS19115 ENOG4105ETX regulatoR HIN87_RS19120 ENOG4105DHQ Histidine kinase HIN87_RS19125 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HIN87_RS19135 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase HIN87_RS19175 ENOG4105VT2 5-hydroxyisourate hydrolase HIN87_RS19185 ENOG4105DY2 Paraquat-inducible protein b HIN87_RS19190 ENOG4105F1S paraquat-inducible protein a HIN87_RS19220 ENOG4105CSH Transporter HIN87_RS19270 ENOG4105JXH GntR family transcriptional regulator HIN87_RS19280 ENOG4105D6U Sodium Glutamate Symporter HIN87_RS19310 ENOG4105H4F exported protein HIN87_RS19345 ENOG4105C26 Dehydrogenase HIN87_RS19350 ENOG4108JPX Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity) HIN87_RS19355 ENOG4105EVZ LysR family transcriptional regulator HIN87_RS19375 ENOG41067NU HIN87_RS19400 ENOG4105D5K Hemolysin activator protein HIN87_RS19425 ENOG4105D9P serine threonine protein kinase HIN87_RS19455 ENOG4105KTH gatB Yqey HIN87_RS19460 ENOG4105ERG peptidase m48, ste24p HIN87_RS19465 ENOG4105C5I Dehydrogenase HIN87_RS19480 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase HIN87_RS19515 ENOG41069NU Nitroreductase HIN87_RS19525 ENOG4105C1J atp-dependent rna helicase HIN87_RS19530 ENOG4105VEQ Cold shock protein HIN87_RS19540 ENOG4105DEK Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) HIN87_RS19545 ENOG4105M08 Membrane HIN87_RS19575 ENOG4105IES Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity) HIN87_RS19580 ENOG4105CIN aminoacyl-histidine dipeptidase HIN87_RS19590 ENOG4105CMY 5-enolpyruvylshikimate-3-phosphate synthase HIN87_RS19595 ENOG4105CQC Prephenate dehydratase HIN87_RS19600 ENOG4105NIV Esterase HIN87_RS19605 ENOG4105C1G acyl-Coa dehydrogenase HIN87_RS19610 ENOG4105CK2 sodium dicarboxylate symporter HIN87_RS19615 ENOG4107QYG anthranilate phosphoribosyltransferase HIN87_RS19620 ENOG4105VUT cytoplasmic protein HIN87_RS19625 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) HIN87_RS19630 ENOG4105BZ4 penicillin-binding protein HIN87_RS19640 ENOG4105M6F mutator MutT protein HIN87_RS19650 ENOG4105DHQ Histidine kinase HIN87_RS19655 ENOG4105XJC Two component transcriptional regulator (Winged helix family HIN87_RS19660 ENOG4108YDI single-species biofilm formation on inanimate substrate HIN87_RS19665 ENOG4107QHF type ii secretion system protein e HIN87_RS19675 ENOG4108R96 Methyltransferase, YaeB family HIN87_RS19680 ENOG4105DP0 ferredoxin-NADP reductase HIN87_RS19685 ENOG4105JAB phenazine biosynthesis protein, phzf family HIN87_RS19690 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family HIN87_RS19695 ENOG4105CFP Peptidase U32 HIN87_RS19700 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding HIN87_RS19715 ENOG4105ENT Efflux transporter rnd family, mfp subunit HIN87_RS19725 ENOG4105ENJ RND efflux system, outer membrane lipoprotein HIN87_RS19920 ENOG4105CQ3 Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity) HIN87_RS19950 ENOG4107QJE Chromosome Partitioning Protein HIN87_RS20020 ENOG4105EJX conjugal transfer ATPase HIN87_RS20115 ENOG4105YES addiction module antidote protein HIN87_RS20120 ENOG4105VUH addiction module killer protein HIN87_RS20145 ENOG4108BUD transposase HIN87_RS20160 ENOG4108BUD transposase HIN87_RS20200 ENOG4105UGU tonB-dependent Receptor HIN87_RS20270 ENOG4108HWY Beta-lactamase