locus-tag	class	description
ACX61_RS00010	COG0592	DNA-directed DNA polymerase activity
ACX61_RS00020	COG0187	DNA topoisomerase II activity
ACX61_RS00030	COG0586	Pfam SNARE associated Golgi protein
ACX61_RS00035	COG0488	(ABC) transporter
ACX61_RS00060	COG0596	Alpha beta hydrolase
ACX61_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ACX61_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACX61_RS00110	COG0733	neurotransmitter:sodium symporter activity
ACX61_RS00145	COG0583	DNA-binding transcription factor activity
ACX61_RS00150	COG2233	PERMEase
ACX61_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_RS00200	COG2814	Major facilitator Superfamily
ACX61_RS00205	COG0656	L-ascorbic acid biosynthetic process
ACX61_RS00210	COG0583	DNA-binding transcription factor activity
ACX61_RS00220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS00225	COG1064	alcohol dehydrogenase
ACX61_RS00230	COG2818	Glycosylase
ACX61_RS00245	COG1194	a g-specific adenine glycosylase
ACX61_RS00265	COG2983	Belongs to the UPF0260 family
ACX61_RS00270	COG2133	pyrroloquinoline quinone binding
ACX61_RS00275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ACX61_RS00280	COG2116	formate transmembrane transporter activity
ACX61_RS00300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_RS00305	COG1335	isochorismatase
ACX61_RS00310	COG0385	Bile acid
ACX61_RS00315	COG0534	Mate efflux family protein
ACX61_RS00320	COG1683	Conserved Protein
ACX61_RS00340	COG0625	glutathione transferase activity
ACX61_RS00350	COG1113	amino acid transport
ACX61_RS00360	COG0523	cobalamin synthesis protein
ACX61_RS00370	COG2188	Transcriptional regulator
ACX61_RS00400	COG0010	Belongs to the arginase family
ACX61_RS00415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX61_RS00420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACX61_RS00430	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACX61_RS00435	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACX61_RS00525	COG0436	Aminotransferase
ACX61_RS00530	COG2733	membrane
ACX61_RS00545	COG2918	glutathione biosynthetic process
ACX61_RS00610	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_RS00695	COG3150	esterase
ACX61_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS00710	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ACX61_RS00720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_RS00735	COG2233	PERMEase
ACX61_RS00740	COG2351	hydroxyisourate hydrolase activity
ACX61_RS00775	COG3706	GGDEF domain
ACX61_RS00790	COG1393	Belongs to the ArsC family
ACX61_RS00795	COG0708	Exodeoxyribonuclease III
ACX61_RS00820	COG0189	ligase activity
ACX61_RS00840	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACX61_RS00850	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACX61_RS00865	COG4942	peptidase
ACX61_RS00875	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX61_RS00885	COG2119	membrane
ACX61_RS00890	COG4774	siderophore transport
ACX61_RS00895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_RS00895	COG0426	domain, Protein
ACX61_RS00920	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACX61_RS00940	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS00945	COG1519	Transferase
ACX61_RS00950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX61_RS00955	COG0668	transmembrane transport
ACX61_RS00965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_RS00970	COG1335	isochorismatase
ACX61_RS00975	COG1522	sequence-specific DNA binding
ACX61_RS01000	COG2205	protein histidine kinase activity
ACX61_RS01000	COG0784	Response regulator, receiver
ACX61_RS01000	COG2198	Histidine kinase
ACX61_RS01005	COG3162	membrane
ACX61_RS01010	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX61_RS01020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_RS01035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACX61_RS01040	COG1309	transcriptional regulator
ACX61_RS01060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX61_RS01060	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_RS01060	COG0351	phosphomethylpyrimidine kinase
ACX61_RS01070	COG2814	Major facilitator Superfamily
ACX61_RS01085	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX61_RS01095	COG1113	amino acid transport
ACX61_RS01105	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX61_RS01110	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS01120	COG1335	isochorismatase
ACX61_RS01150	COG2814	Major facilitator Superfamily
ACX61_RS01155	COG0583	DNA-binding transcription factor activity
ACX61_RS01215	COG0667	Aldo Keto reductase
ACX61_RS01235	COG1129	ABC transporter
ACX61_RS01240	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ACX61_RS01245	COG2207	Transcriptional regulator
ACX61_RS01300	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACX61_RS01315	COG2329	Antibiotic biosynthesis monooxygenase
ACX61_RS01330	COG1132	(ABC) transporter
ACX61_RS01350	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACX61_RS01380	COG0427	acetyl-CoA hydrolase
ACX61_RS01400	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_RS01405	COG4221	oxidoreductase activity
ACX61_RS01415	COG0488	(ABC) transporter
ACX61_RS01480	COG0833	amino acid
ACX61_RS01525	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ACX61_RS01530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACX61_RS01545	COG2226	methyltransferase
ACX61_RS01595	COG0070	glutamate synthase
ACX61_RS01595	COG0069	glutamate synthase activity
ACX61_RS01595	COG0067	glutamate synthase
ACX61_RS01600	COG0493	'glutamate synthase
ACX61_RS01610	COG1704	LemA family
ACX61_RS01615	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ACX61_RS01635	COG3307	-O-antigen
ACX61_RS01655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX61_RS01665	COG0194	GDP metabolic process
ACX61_RS01715	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACX61_RS01735	COG5380	lipid catabolic process
ACX61_RS01740	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACX61_RS01765	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACX61_RS01770	COG0277	FAD linked oxidase domain protein
ACX61_RS01780	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ACX61_RS01785	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_RS01800	COG1289	transmembrane transporter activity
ACX61_RS01810	COG0628	permease
ACX61_RS01815	COG1192	Involved in chromosome partitioning
ACX61_RS01845	COG0833	amino acid
ACX61_RS01850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX61_RS01855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX61_RS01865	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS01905	COG0583	DNA-binding transcription factor activity
ACX61_RS01965	COG0517	IMP dehydrogenase activity
ACX61_RS01970	COG1983	PspC domain protein
ACX61_RS01980	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS01995	COG0408	coproporphyrinogen oxidase activity
ACX61_RS02015	COG0513	Belongs to the DEAD box helicase family
ACX61_RS02025	COG1127	ABC transporter
ACX61_RS02030	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ACX61_RS02040	COG2854	intermembrane phospholipid transfer
ACX61_RS02050	COG0598	Magnesium transport protein CorA
ACX61_RS02060	COG0494	nUDIX hydrolase
ACX61_RS02065	COG1040	competence protein
ACX61_RS02070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACX61_RS02090	COG1946	Acyl-CoA thioesterase
ACX61_RS02095	COG1301	dicarboxylic acid transport
ACX61_RS02110	COG1959	2 iron, 2 sulfur cluster binding
ACX61_RS02115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_RS02115	COG1017	nitric oxide dioxygenase activity
ACX61_RS02120	COG0433	COG0433 Predicted ATPase
ACX61_RS02125	COG0626	cystathionine gamma-synthase activity
ACX61_RS02280	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS02285	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ACX61_RS02315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ACX61_RS02320	COG0339	signal peptide processing
ACX61_RS02325	COG0557	exoribonuclease II activity
ACX61_RS02370	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACX61_RS02375	COG2169	Transcriptional regulator
ACX61_RS02380	COG0697	spore germination
ACX61_RS02385	COG1295	ribonuclease BN
ACX61_RS02420	COG1702	phosphate starvation-inducible protein PhoH
ACX61_RS02430	COG0739	heme binding
ACX61_RS02430	COG0741	lytic transglycosylase activity
ACX61_RS02430	COG1196	nuclear chromosome segregation
ACX61_RS02460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ACX61_RS02465	COG1183	phosphatidylcholine synthase activity
ACX61_RS02510	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS02525	COG2969	positive regulation of protein catabolic process
ACX61_RS02535	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACX61_RS02545	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ACX61_RS02550	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACX61_RS02555	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ACX61_RS02575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACX61_RS02585	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX61_RS02590	COG1408	metallophosphoesterase
ACX61_RS02600	COG2199	diguanylate cyclase activity
ACX61_RS02660	COG1607	acyl-coa hydrolase
ACX61_RS02690	COG2350	Protein conserved in bacteria
ACX61_RS02700	COG0613	PHP domain protein
ACX61_RS02705	COG3781	membrane
ACX61_RS02715	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACX61_RS02720	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ACX61_RS02730	COG1862	Preprotein translocase
ACX61_RS02765	COG2205	protein histidine kinase activity
ACX61_RS02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ACX61_RS02790	COG0726	polysaccharide deacetylase
ACX61_RS02795	COG0463	Glycosyl transferase, family 2
ACX61_RS02800	COG0438	transferase activity, transferring glycosyl groups
ACX61_RS02815	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX61_RS02825	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS02835	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS02880	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS02885	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS02895	COG2205	protein histidine kinase activity
ACX61_RS02900	COG0745	RESPONSE REGULATOR receiver
ACX61_RS02905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ACX61_RS02920	COG0584	glycerophosphoryl diester phosphodiesterase
ACX61_RS02925	COG2096	Adenosyltransferase
ACX61_RS02930	COG4206	TonB-dependent receptor
ACX61_RS02975	COG0285	dihydrofolate synthase activity
ACX61_RS02995	COG0450	alkyl hydroperoxide reductase
ACX61_RS03010	COG0477	Major facilitator Superfamily
ACX61_RS03015	COG1272	protein, Hemolysin III
ACX61_RS03045	COG0183	Belongs to the thiolase family
ACX61_RS03050	COG2207	Transcriptional regulator
ACX61_RS03070	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_RS03090	COG0183	Belongs to the thiolase family
ACX61_RS03100	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ACX61_RS03100	COG2885	chlorophyll binding
ACX61_RS03110	COG1690	Belongs to the RtcB family
ACX61_RS03115	COG0833	amino acid
ACX61_RS03125	COG2233	PERMEase
ACX61_RS03130	COG1217	gtp-binding protein TYPA
ACX61_RS03155	COG2094	Belongs to the DNA glycosylase MPG family
ACX61_RS03160	COG4772	TonB-dependent receptor
ACX61_RS03165	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS03170	COG0679	Auxin Efflux Carrier
ACX61_RS03180	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_RS03185	COG0354	folic acid binding
ACX61_RS03195	COG3189	MarR family transcriptional regulator
ACX61_RS03200	COG2824	Alkylphosphonate utilization operon protein PhnA
ACX61_RS03205	COG3422	double-strand break repair
ACX61_RS03245	COG0840	transmembrane signaling receptor activity
ACX61_RS03265	COG5510	response to toxic substance
ACX61_RS03275	COG2832	Protein of unknown function (DUF454)
ACX61_RS03280	COG1376	ErfK ybiS ycfS ynhG family protein
ACX61_RS03320	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ACX61_RS03330	COG1289	transmembrane transporter activity
ACX61_RS03335	COG2814	Major facilitator Superfamily
ACX61_RS03350	COG1115	amino acid carrier protein
ACX61_RS03355	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX61_RS03360	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX61_RS03365	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
ACX61_RS03370	COG3590	peptidase
ACX61_RS03395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX61_RS03405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACX61_RS03410	COG1077	Cell shape determining protein MreB Mrl
ACX61_RS03415	COG1792	Involved in formation and maintenance of cell shape
ACX61_RS03420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ACX61_RS03425	COG0424	maF-like protein
ACX61_RS03430	COG1530	ribonuclease E activity
ACX61_RS03440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_RS03450	COG0560	Phosphoserine phosphatase
ACX61_RS03460	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_RS03485	COG2207	Transcriptional regulator
ACX61_RS03515	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS03535	COG1113	amino acid transport
ACX61_RS03540	COG2828	Protein conserved in bacteria
ACX61_RS03545	COG0142	geranyltranstransferase activity
ACX61_RS03550	COG2315	Protein conserved in bacteria
ACX61_RS03565	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACX61_RS03585	COG2194	sulfuric ester hydrolase activity
ACX61_RS03590	COG0745	RESPONSE REGULATOR receiver
ACX61_RS03595	COG0642	Histidine kinase
ACX61_RS03605	COG0004	ammonium transporteR
ACX61_RS03610	COG0583	DNA-binding transcription factor activity
ACX61_RS03625	COG2226	methyltransferase
ACX61_RS03630	COG0525	valine-tRNA ligase activity
ACX61_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS03650	COG0393	Putative heavy-metal-binding
ACX61_RS03655	COG0393	Putative heavy-metal-binding
ACX61_RS03660	COG1538	Outer membrane efflux protein
ACX61_RS03670	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_RS03675	COG0671	phosphoesterase, PA-phosphatase related
ACX61_RS03705	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACX61_RS03720	COG1648	precorrin-2 dehydrogenase activity
ACX61_RS03720	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACX61_RS03725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ACX61_RS03740	COG0531	amino acid
ACX61_RS03755	COG0321	lipoyl(octanoyl) transferase activity
ACX61_RS03760	COG2921	Belongs to the UPF0250 family
ACX61_RS03795	COG2009	succinate dehydrogenase
ACX61_RS03800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ACX61_RS03805	COG1053	succinate dehydrogenase
ACX61_RS03810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACX61_RS03825	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_RS03845	COG2354	Protein conserved in bacteria
ACX61_RS03850	COG2321	neutral zinc metallopeptidase
ACX61_RS03870	COG2843	Capsule synthesis protein
ACX61_RS03885	COG0589	response to stress
ACX61_RS03895	COG0251	oxidation-reduction process
ACX61_RS03900	COG1309	transcriptional regulator
ACX61_RS03915	COG0505	Belongs to the CarA family
ACX61_RS03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX61_RS03945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACX61_RS03995	COG0477	Major facilitator Superfamily
ACX61_RS04000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACX61_RS04015	COG1597	lipid kinase activity
ACX61_RS04020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX61_RS04045	COG0584	glycerophosphoryl diester phosphodiesterase
ACX61_RS04065	COG0741	lytic transglycosylase activity
ACX61_RS04085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACX61_RS04095	COG0582	viral genome integration into host DNA
ACX61_RS04120	COG2217	Heavy metal translocating P-type atpase
ACX61_RS04125	COG2205	protein histidine kinase activity
ACX61_RS04140	COG2132	Multicopper oxidase
ACX61_RS04170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_RS04185	COG0778	Nitroreductase
ACX61_RS04200	COG1929	Belongs to the glycerate kinase type-1 family
ACX61_RS04205	COG0243	molybdopterin cofactor binding
ACX61_RS04210	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACX61_RS04215	COG3339	Conserved Protein
ACX61_RS04225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ACX61_RS04250	COG1115	amino acid carrier protein
ACX61_RS04255	COG1113	amino acid transport
ACX61_RS04265	COG0019	diaminopimelate decarboxylase activity
ACX61_RS04275	COG2267	carboxylic ester hydrolase activity
ACX61_RS04280	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS04285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ACX61_RS04315	COG0463	Glycosyl transferase, family 2
ACX61_RS04335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_RS04365	COG4591	ABC-type transport system involved in lipoprotein release permease component
ACX61_RS04370	COG1136	(ABC) transporter
ACX61_RS04375	COG2333	competence protein COMEC
ACX61_RS04375	COG0658	competence protein
ACX61_RS04385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ACX61_RS04385	COG0616	signal peptide processing
ACX61_RS04390	COG0596	Alpha beta hydrolase
ACX61_RS04395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACX61_RS04405	COG0628	permease
ACX61_RS04440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX61_RS04460	COG0823	Involved in the tonB-independent uptake of proteins
ACX61_RS04480	COG0824	Thioesterase
ACX61_RS04485	COG1473	amidohydrolase
ACX61_RS04505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACX61_RS04505	COG0047	phosphoribosylformylglycinamidine synthase activity
ACX61_RS04510	COG2814	Major facilitator Superfamily
ACX61_RS04525	COG1024	Enoyl-CoA hydratase
ACX61_RS04530	COG1056	cytidyltransferase-related domain
ACX61_RS04530	COG1051	belongs to the nudix hydrolase family
ACX61_RS04540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACX61_RS04555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACX61_RS04570	COG4625	pathogenesis
ACX61_RS04575	COG0583	DNA-binding transcription factor activity
ACX61_RS04580	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ACX61_RS04585	COG4208	sulfate ABC transporter
ACX61_RS04590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ACX61_RS04600	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ACX61_RS04605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACX61_RS04610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACX61_RS04630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX61_RS04645	COG0681	Belongs to the peptidase S26 family
ACX61_RS04660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACX61_RS04670	COG1381	Involved in DNA repair and RecF pathway recombination
ACX61_RS04675	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ACX61_RS04685	COG4221	oxidoreductase activity
ACX61_RS04710	COG0443	Heat shock 70 kDa protein
ACX61_RS04720	COG0436	Aminotransferase
ACX61_RS04740	COG0556	nucleotide-excision repair
ACX61_RS04795	COG2070	2-Nitropropane dioxygenase
ACX61_RS04825	COG1215	transferase activity, transferring glycosyl groups
ACX61_RS04840	COG0415	Belongs to the DNA photolyase family
ACX61_RS04850	COG1252	NADH dehydrogenase
ACX61_RS04855	COG1686	Belongs to the peptidase S11 family
ACX61_RS04870	COG1187	pseudouridine synthase activity
ACX61_RS04890	COG0477	Major facilitator Superfamily
ACX61_RS04895	COG0583	DNA-binding transcription factor activity
ACX61_RS04900	COG1823	symporter activity
ACX61_RS04910	COG0612	Peptidase, M16
ACX61_RS04935	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_RS04970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_RS04985	COG1309	transcriptional regulator
ACX61_RS04995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACX61_RS05000	COG0076	glutamate decarboxylase activity
ACX61_RS05010	COG1522	sequence-specific DNA binding
ACX61_RS05015	COG3961	Belongs to the TPP enzyme family
ACX61_RS05020	COG1113	amino acid transport
ACX61_RS05025	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ACX61_RS05030	COG0573	inorganic phosphate transmembrane transporter activity
ACX61_RS05040	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACX61_RS05045	COG0616	signal peptide processing
ACX61_RS05080	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ACX61_RS05085	COG1686	Belongs to the peptidase S11 family
ACX61_RS05110	COG0583	DNA-binding transcription factor activity
ACX61_RS05115	COG1067	ATP-dependent peptidase activity
ACX61_RS05140	COG4943	cyclic-guanylate-specific phosphodiesterase activity
ACX61_RS05160	COG1966	Carbon starvation protein
ACX61_RS05165	COG2879	small protein
ACX61_RS05205	COG1741	Belongs to the pirin family
ACX61_RS05215	COG2964	Protein conserved in bacteria
ACX61_RS05230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_RS05235	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX61_RS05240	COG4605	iron ion homeostasis
ACX61_RS05245	COG4604	ABC transporter, ATP-binding protein
ACX61_RS05250	COG4607	ABC-type enterochelin transport system periplasmic component
ACX61_RS05255	COG4774	siderophore transport
ACX61_RS05265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ACX61_RS05270	COG1021	2,3-dihydroxybenzoate-AMP ligase
ACX61_RS05275	COG1535	isochorismatase
ACX61_RS05275	COG3433	isochorismatase activity
ACX61_RS05290	COG1132	(ABC) transporter
ACX61_RS05295	COG1132	(ABC) transporter
ACX61_RS05300	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACX61_RS05310	COG1169	isochorismate synthase
ACX61_RS05325	COG3739	integral membrane protein
ACX61_RS05345	COG0302	gtp cyclohydrolase
ACX61_RS05355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ACX61_RS05385	COG0308	aminopeptidase N
ACX61_RS05390	COG0512	Glutamine amidotransferase of anthranilate synthase
ACX61_RS05405	COG0174	glutamine synthetase
ACX61_RS05415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ACX61_RS05450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ACX61_RS05455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACX61_RS05460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACX61_RS05480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACX61_RS05485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACX61_RS05490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACX61_RS05505	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS05510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX61_RS05515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_RS05530	COG2223	nitrite transmembrane transporter activity
ACX61_RS05540	COG0024	Methionine aminopeptidase
ACX61_RS05545	COG0052	Belongs to the universal ribosomal protein uS2 family
ACX61_RS05560	COG2207	Transcriptional regulator
ACX61_RS05585	COG2951	lytic endotransglycosylase activity
ACX61_RS05590	COG0772	Belongs to the SEDS family
ACX61_RS05605	COG0842	Transport permease protein
ACX61_RS05610	COG1131	(ABC) transporter
ACX61_RS05615	COG0582	viral genome integration into host DNA
ACX61_RS05815	COG5410	chromosome segregation
ACX61_RS06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_RS06010	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS06020	COG4215	(ABC) transporter
ACX61_RS06025	COG4160	amino acid transport
ACX61_RS06030	COG4598	ABC transporter
ACX61_RS06040	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX61_RS06045	COG0826	peptidase U32
ACX61_RS06050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS06055	COG0384	phenazine biosynthesis protein PhzF
ACX61_RS06065	COG1720	tRNA m6t6A37 methyltransferase activity
ACX61_RS06075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACX61_RS06090	COG0642	Histidine kinase
ACX61_RS06100	COG0494	nUDIX hydrolase
ACX61_RS06110	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACX61_RS06115	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACX61_RS06120	COG3139	Protein of unknown function (DUF1315)
ACX61_RS06125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACX61_RS06130	COG1301	dicarboxylic acid transport
ACX61_RS06135	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS06150	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACX61_RS06160	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACX61_RS06180	COG1690	Belongs to the RtcB family
ACX61_RS06185	COG1234	tRNA 3'-trailer cleavage
ACX61_RS06190	COG4650	regulator
ACX61_RS06220	COG2363	Small membrane protein
ACX61_RS06240	COG0513	Belongs to the DEAD box helicase family
ACX61_RS06250	COG0778	Nitroreductase
ACX61_RS06390	COG1286	toxin biosynthetic process
ACX61_RS06415	COG4783	chaperone-mediated protein folding
ACX61_RS06420	COG1610	YqeY-like protein
ACX61_RS06520	COG3111	PFAM Bacterial OB fold (BOF) protein
ACX61_RS06545	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACX61_RS06550	COG0786	glutamate:sodium symporter activity
ACX61_RS06560	COG2186	Transcriptional regulator
ACX61_RS06565	COG1051	belongs to the nudix hydrolase family
ACX61_RS06595	COG2995	paraquat-inducible protein a
ACX61_RS06600	COG3008	intermembrane lipid transfer
ACX61_RS06600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ACX61_RS06610	COG2351	hydroxyisourate hydrolase activity
ACX61_RS06650	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACX61_RS06660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ACX61_RS06665	COG0642	Histidine kinase
ACX61_RS06670	COG0745	RESPONSE REGULATOR receiver
ACX61_RS06690	COG1794	racemase activity, acting on amino acids and derivatives
ACX61_RS06720	COG1301	dicarboxylic acid transport
ACX61_RS06730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_RS06735	COG2011	ABC-type metal ion transport system permease component
ACX61_RS06740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX61_RS06745	COG1464	Belongs to the NlpA lipoprotein family
ACX61_RS06750	COG0151	Belongs to the GarS family
ACX61_RS06755	COG0138	bifunctional purine biosynthesis protein purh
ACX61_RS06760	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ACX61_RS06790	COG2308	Evidence 4 Homologs of previously reported genes of
ACX61_RS06800	COG1305	Transglutaminase-like
ACX61_RS06810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACX61_RS06815	COG0305	Participates in initiation and elongation during chromosome replication
ACX61_RS06840	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACX61_RS06850	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACX61_RS06855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACX61_RS06880	COG1649	PFAM Uncharacterised BCR, COG1649
ACX61_RS06880	COG0726	polysaccharide deacetylase
ACX61_RS06885	COG1215	transferase activity, transferring glycosyl groups
ACX61_RS06890	COG3658	cytochrome
ACX61_RS06900	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX61_RS06920	COG0583	DNA-binding transcription factor activity
ACX61_RS06950	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS06955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_RS06960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_RS06985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ACX61_RS06990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACX61_RS06995	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACX61_RS07000	COG2205	protein histidine kinase activity
ACX61_RS07005	COG0745	RESPONSE REGULATOR receiver
ACX61_RS07010	COG0174	glutamine synthetase
ACX61_RS07030	COG0729	surface antigen
ACX61_RS07150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX61_RS07155	COG2814	Major facilitator Superfamily
ACX61_RS07170	COG0583	DNA-binding transcription factor activity
ACX61_RS07185	COG1187	pseudouridine synthase activity
ACX61_RS07205	COG0802	atpase or kinase
ACX61_RS07210	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACX61_RS07220	COG1923	regulation of RNA biosynthetic process
ACX61_RS07225	COG0697	spore germination
ACX61_RS07240	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_RS07250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX61_RS07255	COG0519	Catalyzes the synthesis of GMP from XMP
ACX61_RS07255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX61_RS07260	COG4302	ethanolamine ammonia-lyase activity
ACX61_RS07265	COG4303	Ethanolamine ammonia lyase large subunit
ACX61_RS07270	COG0531	amino acid
ACX61_RS07290	COG1454	alcohol dehydrogenase
ACX61_RS07295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX61_RS07320	COG0308	aminopeptidase N
ACX61_RS07360	COG1605	Chorismate mutase
ACX61_RS07375	COG1309	transcriptional regulator
ACX61_RS07385	COG0668	transmembrane transport
ACX61_RS07415	COG3328	transposase activity
ACX61_RS07425	COG4773	Receptor
ACX61_RS07445	COG0488	(ABC) transporter
ACX61_RS07450	COG0589	response to stress
ACX61_RS07470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACX61_RS07480	COG3135	benzoate transporter
ACX61_RS07485	COG1522	sequence-specific DNA binding
ACX61_RS07495	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACX61_RS07500	COG0583	DNA-binding transcription factor activity
ACX61_RS07510	COG0183	Belongs to the thiolase family
ACX61_RS07520	COG2030	dehydratase
ACX61_RS07525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACX61_RS07550	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACX61_RS07560	COG0824	Thioesterase
ACX61_RS07565	COG1454	alcohol dehydrogenase
ACX61_RS07575	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACX61_RS07605	COG0069	glutamate synthase activity
ACX61_RS07755	COG5410	chromosome segregation
ACX61_RS07855	COG1598	PFAM Uncharacterised protein family UPF0150
ACX61_RS07905	COG3179	chitinase
ACX61_RS07915	COG1063	alcohol dehydrogenase
ACX61_RS07920	COG3293	Transposase
ACX61_RS07950	COG2814	Major facilitator Superfamily
ACX61_RS07965	COG0511	ligase activity, forming carbon-carbon bonds
ACX61_RS07980	COG1116	anion transmembrane transporter activity
ACX61_RS07980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_RS07985	COG0745	RESPONSE REGULATOR receiver
ACX61_RS07995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_RS07995	COG2146	nitrite reductase [NAD(P)H] activity
ACX61_RS08000	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_RS08005	COG0243	molybdopterin cofactor binding
ACX61_RS08020	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACX61_RS08035	COG0315	cyclic pyranopterin monophosphate synthase activity
ACX61_RS08035	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACX61_RS08040	COG0303	'Molybdopterin
ACX61_RS08050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS08055	COG0697	spore germination
ACX61_RS08075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ACX61_RS08080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX61_RS08135	COG2204	response regulator
ACX61_RS08140	COG3852	Histidine kinase
ACX61_RS08160	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACX61_RS08165	COG0575	Belongs to the CDS family
ACX61_RS08180	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX61_RS08200	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_RS08210	COG2137	regulation of response to DNA damage stimulus
ACX61_RS08220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACX61_RS08225	COG1011	Hydrolase
ACX61_RS08250	COG1522	sequence-specific DNA binding
ACX61_RS08260	COG1113	amino acid transport
ACX61_RS08275	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_RS08280	COG2135	peptidase activity
ACX61_RS08295	COG5001	Diguanylate cyclase
ACX61_RS08295	COG3300	MHYT domain
ACX61_RS08310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX61_RS08310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ACX61_RS08310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ACX61_RS08315	COG1105	Belongs to the carbohydrate kinase PfkB family
ACX61_RS08320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACX61_RS08320	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX61_RS08350	COG0024	Methionine aminopeptidase
ACX61_RS08355	COG0583	DNA-binding transcription factor activity
ACX61_RS08365	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ACX61_RS08370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACX61_RS08375	COG0517	IMP dehydrogenase activity
ACX61_RS08375	COG0516	GMP reductase activity
ACX61_RS08400	COG0552	protein localization to endoplasmic reticulum
ACX61_RS08410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
ACX61_RS08425	COG4890	Cyd operon protein YbgT
ACX61_RS08430	COG1294	oxidase, subunit
ACX61_RS08445	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS08450	COG1585	Membrane protein implicated in regulation of membrane protease activity
ACX61_RS08460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACX61_RS08465	COG4774	siderophore transport
ACX61_RS08480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACX61_RS08485	COG0569	domain protein
ACX61_RS08490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACX61_RS08530	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ACX61_RS08535	COG0542	response to heat
ACX61_RS08560	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS08560	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_RS08605	COG2323	membrane
ACX61_RS08610	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ACX61_RS08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_RS08625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_RS08630	COG0183	Belongs to the thiolase family
ACX61_RS08635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACX61_RS08640	COG0596	Alpha beta hydrolase
ACX61_RS08645	COG2271	Major facilitator Superfamily
ACX61_RS08650	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACX61_RS08655	COG3485	protocatechuate 3,4-dioxygenase
ACX61_RS08660	COG3485	protocatechuate 3,4-dioxygenase
ACX61_RS08665	COG0710	3-dehydroquinate dehydratase activity
ACX61_RS08670	COG3420	alginic acid biosynthetic process
ACX61_RS08675	COG3659	wide pore channel activity
ACX61_RS08680	COG4993	Dehydrogenase
ACX61_RS08690	COG2391	methyltransferase activity
ACX61_RS08705	COG1414	Transcriptional regulator
ACX61_RS08710	COG0583	DNA-binding transcription factor activity
ACX61_RS08715	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS08740	COG2814	Major facilitator Superfamily
ACX61_RS08750	COG0154	amidase activity
ACX61_RS08770	COG4638	Rieske (2fe-2S)
ACX61_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS08790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_RS08800	COG3733	amine oxidase
ACX61_RS08810	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS08820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_RS08825	COG0183	Belongs to the thiolase family
ACX61_RS08830	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_RS08835	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_RS08845	COG4829	muconolactone delta-isomerase
ACX61_RS08850	COG4948	Mandelate Racemase Muconate Lactonizing
ACX61_RS08855	COG0583	DNA-binding transcription factor activity
ACX61_RS08865	COG2186	Transcriptional regulator
ACX61_RS08885	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS08900	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_RS08900	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS08940	COG1309	transcriptional regulator
ACX61_RS08945	COG0583	DNA-binding transcription factor activity
ACX61_RS08950	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS08960	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS08970	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS08980	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_RS09025	COG2188	Transcriptional regulator
ACX61_RS09040	COG0583	DNA-binding transcription factor activity
ACX61_RS09060	COG1566	PFAM secretion protein HlyD family protein
ACX61_RS09075	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS09080	COG0129	dihydroxy-acid dehydratase activity
ACX61_RS09090	COG0583	DNA-binding transcription factor activity
ACX61_RS09095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACX61_RS09105	COG2084	Dehydrogenase
ACX61_RS09115	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACX61_RS09120	COG1120	ATPase activity
ACX61_RS09140	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX61_RS09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACX61_RS09245	COG2205	protein histidine kinase activity
ACX61_RS09265	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS09275	COG3539	Fimbrial protein
ACX61_RS09300	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACX61_RS09310	COG0753	catalase activity
ACX61_RS09325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACX61_RS09385	COG1535	isochorismatase
ACX61_RS09385	COG3433	isochorismatase activity
ACX61_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS09395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ACX61_RS09400	COG4149	molybdate abc transporter
ACX61_RS09405	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACX61_RS09415	COG4638	Rieske (2fe-2S)
ACX61_RS09420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX61_RS09425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_RS09425	COG0543	2 iron, 2 sulfur cluster binding
ACX61_RS09440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS09455	COG3328	transposase activity
ACX61_RS09475	COG2207	Transcriptional regulator
ACX61_RS09480	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS09485	COG2610	gluconate transmembrane transporter activity
ACX61_RS09495	COG0583	DNA-binding transcription factor activity
ACX61_RS09510	COG2031	fatty acid transporter
ACX61_RS09515	COG0183	Belongs to the thiolase family
ACX61_RS09520	COG0583	DNA-binding transcription factor activity
ACX61_RS09525	COG0583	DNA-binding transcription factor activity
ACX61_RS09540	COG1027	Aspartate ammonia-lyase
ACX61_RS09550	COG0477	Major facilitator Superfamily
ACX61_RS09570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX61_RS09575	COG4521	taurine ABC transporter
ACX61_RS09590	COG2188	Transcriptional regulator
ACX61_RS09600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACX61_RS09610	COG2207	Transcriptional regulator
ACX61_RS09610	COG3708	Transcriptional regulator
ACX61_RS09625	COG0730	response to heat
ACX61_RS09635	COG3453	Protein conserved in bacteria
ACX61_RS09635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_RS09645	COG3781	membrane
ACX61_RS09650	COG1063	alcohol dehydrogenase
ACX61_RS09660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACX61_RS09665	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACX61_RS09670	COG0022	dehydrogenase e1 component
ACX61_RS09675	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACX61_RS09680	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACX61_RS09695	COG3706	GGDEF domain
ACX61_RS09710	COG0133	tryptophan synthase activity
ACX61_RS09720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACX61_RS09755	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ACX61_RS09790	COG2226	methyltransferase
ACX61_RS09820	COG0537	adenosine 5'-monophosphoramidase activity
ACX61_RS09845	COG0842	Transport permease protein
ACX61_RS09850	COG0842	Transport permease protein
ACX61_RS09855	COG1131	(ABC) transporter
ACX61_RS09870	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ACX61_RS09875	COG4773	Receptor
ACX61_RS09895	COG0730	response to heat
ACX61_RS09900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ACX61_RS09915	COG0406	alpha-ribazole phosphatase activity
ACX61_RS09920	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACX61_RS09935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX61_RS09965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX61_RS09975	COG4264	IucA IucC family
ACX61_RS09980	COG4264	IucA IucC family
ACX61_RS09985	COG2814	Major facilitator Superfamily
ACX61_RS10000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ACX61_RS10015	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS10020	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS10025	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ACX61_RS10030	COG2207	Transcriptional regulator
ACX61_RS10035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX61_RS10040	COG0776	regulation of translation
ACX61_RS10065	COG0822	iron-sulfur transferase activity
ACX61_RS10070	COG0316	Belongs to the HesB IscA family
ACX61_RS10100	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACX61_RS10120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACX61_RS10125	COG0702	epimerase
ACX61_RS10165	COG0601	transmembrane transport
ACX61_RS10170	COG0339	signal peptide processing
ACX61_RS10175	COG4166	transmembrane transport
ACX61_RS10215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACX61_RS10220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ACX61_RS10250	COG0776	regulation of translation
ACX61_RS10315	COG0084	hydrolase, TatD family'
ACX61_RS10335	COG1663	tetraacyldisaccharide 4'-kinase activity
ACX61_RS10340	COG1132	(ABC) transporter
ACX61_RS10350	COG0811	peptide transport
ACX61_RS10355	COG1475	DNA binding
ACX61_RS10360	COG1192	Involved in chromosome partitioning
ACX61_RS10370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX61_RS10385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACX61_RS10390	COG0191	fructose-bisphosphate aldolase activity
ACX61_RS10410	COG0424	maF-like protein
ACX61_RS10415	COG2850	peptidyl-arginine hydroxylation
ACX61_RS10425	COG0640	Transcriptional regulator
ACX61_RS10435	COG3619	membrane
ACX61_RS10440	COG3122	Protein conserved in bacteria
ACX61_RS10445	COG3328	transposase activity
ACX61_RS10450	COG1132	(ABC) transporter
ACX61_RS10470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ACX61_RS10475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACX61_RS10485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX61_RS10485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ACX61_RS10485	COG0506	proline dehydrogenase activity
ACX61_RS10490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ACX61_RS10505	COG3698	Phosphodiester glycosidase
ACX61_RS10515	COG2353	YceI-like domain
ACX61_RS10525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACX61_RS10570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACX61_RS10570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACX61_RS10595	COG3539	Fimbrial protein
ACX61_RS10600	COG3121	Chaperone
ACX61_RS10620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
ACX61_RS10630	COG0583	DNA-binding transcription factor activity
ACX61_RS10635	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS10655	COG1309	transcriptional regulator
ACX61_RS10670	COG1522	sequence-specific DNA binding
ACX61_RS10680	COG1126	abc transporter atp-binding protein
ACX61_RS10685	COG0765	amino acid transport
ACX61_RS10690	COG0765	amino acid transport
ACX61_RS10720	COG1464	Belongs to the NlpA lipoprotein family
ACX61_RS10730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACX61_RS10735	COG2011	ABC-type metal ion transport system permease component
ACX61_RS10740	COG0012	GTP binding
ACX61_RS10765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACX61_RS10805	COG0386	Belongs to the glutathione peroxidase family
ACX61_RS10815	COG0436	Aminotransferase
ACX61_RS10820	COG1301	dicarboxylic acid transport
ACX61_RS10855	COG3634	alkyl hydroperoxide reductase activity
ACX61_RS10870	COG0583	DNA-binding transcription factor activity
ACX61_RS10875	COG0798	PFAM Bile acid sodium symporter
ACX61_RS10880	COG0640	Transcriptional regulator
ACX61_RS10910	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ACX61_RS10920	COG0583	DNA-binding transcription factor activity
ACX61_RS10930	COG1953	Uracil, thiamine, allantoin
ACX61_RS10940	COG2175	clavaminate synthase activity
ACX61_RS10945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ACX61_RS10950	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ACX61_RS10955	COG4521	taurine ABC transporter
ACX61_RS10965	COG0477	Major facilitator Superfamily
ACX61_RS10985	COG1271	oxidase subunit
ACX61_RS10990	COG1294	oxidase, subunit
ACX61_RS11000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS11020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACX61_RS11040	COG3052	prosthetic group binding
ACX61_RS11045	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
ACX61_RS11055	COG2814	Major facilitator Superfamily
ACX61_RS11070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS11075	COG1346	cytolysis
ACX61_RS11085	COG0583	DNA-binding transcription factor activity
ACX61_RS11090	COG0625	glutathione transferase activity
ACX61_RS11095	COG0625	glutathione transferase activity
ACX61_RS11100	COG0583	DNA-binding transcription factor activity
ACX61_RS11105	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS11115	COG1045	serine acetyltransferase
ACX61_RS11120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACX61_RS11125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACX61_RS11130	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS11140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_RS11150	COG1126	abc transporter atp-binding protein
ACX61_RS11155	COG0765	amino acid transport
ACX61_RS11160	COG0765	amino acid transport
ACX61_RS11175	COG0784	Response regulator, receiver
ACX61_RS11175	COG2205	protein histidine kinase activity
ACX61_RS11195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACX61_RS11215	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS11265	COG0583	DNA-binding transcription factor activity
ACX61_RS11285	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_RS11290	COG1309	transcriptional regulator
ACX61_RS11295	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS11300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACX61_RS11305	COG1024	Enoyl-CoA hydratase
ACX61_RS11310	COG4770	biotin carboxylase activity
ACX61_RS11320	COG0583	DNA-binding transcription factor activity
ACX61_RS11335	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS11345	COG2814	Major facilitator Superfamily
ACX61_RS11355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACX61_RS11360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACX61_RS11365	COG2814	Major facilitator Superfamily
ACX61_RS11370	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS11375	COG1024	Enoyl-CoA hydratase
ACX61_RS11380	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS11385	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_RS11390	COG0183	Belongs to the thiolase family
ACX61_RS11400	COG2814	Major facilitator Superfamily
ACX61_RS11410	COG1024	Enoyl-CoA hydratase
ACX61_RS11425	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS11430	COG2814	Major facilitator Superfamily
ACX61_RS11435	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACX61_RS11440	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACX61_RS11455	COG3842	ATPase activity
ACX61_RS11460	COG1840	ABC-type Fe3 transport system, periplasmic component
ACX61_RS11475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_RS11480	COG1414	Transcriptional regulator
ACX61_RS11490	COG0583	DNA-binding transcription factor activity
ACX61_RS11495	COG3038	cytochrome b561
ACX61_RS11500	COG0753	catalase activity
ACX61_RS11535	COG0406	alpha-ribazole phosphatase activity
ACX61_RS11540	COG3328	transposase activity
ACX61_RS11550	COG2050	protein possibly involved in aromatic compounds catabolism
ACX61_RS11560	COG3327	negative regulation of DNA-templated transcription, initiation
ACX61_RS11565	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACX61_RS11570	COG0183	Belongs to the thiolase family
ACX61_RS11575	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_RS11580	COG1024	Enoyl-CoA hydratase
ACX61_RS11585	COG1024	Enoyl-CoA hydratase
ACX61_RS11590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_RS11595	COG2151	metal-sulfur cluster biosynthetic enzyme
ACX61_RS11600	COG3396	Phenylacetate-CoA oxygenase
ACX61_RS11605	COG3460	Phenylacetate-CoA oxygenase
ACX61_RS11610	COG3396	Phenylacetate-CoA oxygenase
ACX61_RS11615	COG2030	dehydratase
ACX61_RS11615	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS11620	COG1760	l-serine dehydratase
ACX61_RS11625	COG0531	amino acid
ACX61_RS11630	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS11675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_RS11690	COG0789	Transcriptional regulator
ACX61_RS11700	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ACX61_RS11715	COG2807	transmembrane transport
ACX61_RS11720	COG0590	tRNA wobble adenosine to inosine editing
ACX61_RS11885	COG1116	anion transmembrane transporter activity
ACX61_RS11890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACX61_RS11900	COG0864	Transcriptional regulator
ACX61_RS11915	COG1733	regulation of RNA biosynthetic process
ACX61_RS11920	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACX61_RS11925	COG0439	Biotin carboxylase
ACX61_RS11940	COG1063	alcohol dehydrogenase
ACX61_RS11950	COG1309	transcriptional regulator
ACX61_RS11955	COG3328	transposase activity
ACX61_RS11970	COG0038	chloride channel
ACX61_RS11975	COG4770	biotin carboxylase activity
ACX61_RS11995	COG1914	H( )-stimulated, divalent metal cation uptake system
ACX61_RS12000	COG0583	DNA-binding transcription factor activity
ACX61_RS12015	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS12035	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACX61_RS12055	COG2814	Major facilitator Superfamily
ACX61_RS12065	COG1560	Kdo2-lipid A biosynthetic process
ACX61_RS12075	COG5006	permease, DMT superfamily
ACX61_RS12080	COG1522	sequence-specific DNA binding
ACX61_RS12095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ACX61_RS12105	COG4122	O-methyltransferase activity
ACX61_RS12140	COG1137	ATPase activity
ACX61_RS12145	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ACX61_RS12155	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ACX61_RS12185	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS12210	COG2814	Major facilitator Superfamily
ACX61_RS12240	COG1278	Cold shock
ACX61_RS12245	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS12275	COG1570	exodeoxyribonuclease VII activity
ACX61_RS12325	COG0583	DNA-binding transcription factor activity
ACX61_RS12330	COG4638	Rieske (2fe-2S)
ACX61_RS12335	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
ACX61_RS12340	COG0543	2 iron, 2 sulfur cluster binding
ACX61_RS12340	COG0633	Ferredoxin
ACX61_RS12345	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS12350	COG3135	benzoate transporter
ACX61_RS12355	COG2814	Major facilitator Superfamily
ACX61_RS12370	COG1643	Atp-dependent helicase
ACX61_RS12375	COG0450	alkyl hydroperoxide reductase
ACX61_RS12385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ACX61_RS12395	COG3634	alkyl hydroperoxide reductase activity
ACX61_RS12415	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACX61_RS12435	COG0625	glutathione transferase activity
ACX61_RS12445	COG2885	chlorophyll binding
ACX61_RS12480	COG0542	response to heat
ACX61_RS12495	COG3328	transposase activity
ACX61_RS12500	COG1765	OsmC-like protein
ACX61_RS12510	COG0667	Aldo Keto reductase
ACX61_RS12525	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACX61_RS12535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACX61_RS12545	COG0582	viral genome integration into host DNA
ACX61_RS12555	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS12575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX61_RS12655	COG0592	DNA-directed DNA polymerase activity
ACX61_RS12835	COG3755	Protein conserved in bacteria
ACX61_RS12880	COG1484	DNA-dependent DNA replication
ACX61_RS12975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_RS13015	COG0527	aspartate kinase activity
ACX61_RS13025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACX61_RS13035	COG3038	cytochrome b561
ACX61_RS13040	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ACX61_RS13045	COG2252	PERMEase
ACX61_RS13055	COG2072	flavoprotein involved in K transport
ACX61_RS13070	COG1741	Belongs to the pirin family
ACX61_RS13075	COG1309	transcriptional regulator
ACX61_RS13085	COG0300	oxidoreductase activity
ACX61_RS13090	COG2072	flavoprotein involved in K transport
ACX61_RS13095	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACX61_RS13155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ACX61_RS13170	COG2814	Major facilitator Superfamily
ACX61_RS13175	COG1024	Enoyl-CoA hydratase
ACX61_RS13180	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS13190	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS13215	COG2186	Transcriptional regulator
ACX61_RS13220	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS13230	COG4948	Mandelate Racemase Muconate Lactonizing
ACX61_RS13235	COG2271	Major facilitator Superfamily
ACX61_RS13240	COG2721	sulfolactate sulfo-lyase activity
ACX61_RS13245	COG0697	spore germination
ACX61_RS13270	COG1113	amino acid transport
ACX61_RS13290	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS13320	COG1113	amino acid transport
ACX61_RS13350	COG4269	membrane
ACX61_RS13355	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS13385	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACX61_RS13385	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
ACX61_RS13410	COG0514	ATP-dependent DNA helicase (RecQ)
ACX61_RS13510	COG2161	toxin-antitoxin pair type II binding
ACX61_RS13520	COG3328	transposase activity
ACX61_RS13530	COG0582	viral genome integration into host DNA
ACX61_RS13540	COG0446	pyridine nucleotide-disulphide oxidoreductase
ACX61_RS13540	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS13550	COG2203	Gaf domain
ACX61_RS13550	COG3706	GGDEF domain
ACX61_RS13550	COG4251	negative regulation of phosphorylation
ACX61_RS13550	COG5001	Diguanylate cyclase
ACX61_RS13560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_RS13580	COG4172	Belongs to the ABC transporter superfamily
ACX61_RS13585	COG4239	(ABC) transporter, permease
ACX61_RS13590	COG4174	ABC transporter (Permease)
ACX61_RS13600	COG0741	lytic transglycosylase activity
ACX61_RS13600	COG1388	LysM domain
ACX61_RS13605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACX61_RS13645	COG0583	DNA-binding transcription factor activity
ACX61_RS13650	COG1279	arginine transmembrane transporter activity
ACX61_RS13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_RS13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_RS13680	COG0006	proline dipeptidase activity
ACX61_RS13705	COG2194	sulfuric ester hydrolase activity
ACX61_RS13820	COG3620	sequence-specific DNA binding
ACX61_RS13865	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACX61_RS13880	COG3384	dioxygenase
ACX61_RS13890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACX61_RS13895	COG2878	Part of a membrane complex involved in electron transport
ACX61_RS13900	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACX61_RS13920	COG0768	penicillin binding
ACX61_RS13925	COG0742	ribosomal rna small subunit methyltransferase
ACX61_RS13940	COG0830	nickel cation binding
ACX61_RS13950	COG0804	urea catabolic process
ACX61_RS13990	COG1253	flavin adenine dinucleotide binding
ACX61_RS13995	COG2851	Citrate transporter
ACX61_RS14040	COG1773	rubredoxin
ACX61_RS14045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACX61_RS14055	COG0583	DNA-binding transcription factor activity
ACX61_RS14080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ACX61_RS14085	COG4181	ATPase activity
ACX61_RS14130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ACX61_RS14150	COG0306	phosphate transporter
ACX61_RS14180	COG2223	nitrite transmembrane transporter activity
ACX61_RS14185	COG2207	Transcriptional regulator
ACX61_RS14190	COG2066	Belongs to the glutaminase family
ACX61_RS14195	COG0242	peptide deformylase activity
ACX61_RS14200	COG0477	Major facilitator Superfamily
ACX61_RS14210	COG0028	Belongs to the TPP enzyme family
ACX61_RS14225	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS14230	COG2267	carboxylic ester hydrolase activity
ACX61_RS14240	COG2271	Major facilitator Superfamily
ACX61_RS14255	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS14275	COG1414	Transcriptional regulator
ACX61_RS14290	COG1024	Enoyl-CoA hydratase
ACX61_RS14300	COG1215	transferase activity, transferring glycosyl groups
ACX61_RS14305	COG0726	polysaccharide deacetylase
ACX61_RS14305	COG1649	PFAM Uncharacterised BCR, COG1649
ACX61_RS14315	COG4681	YaeQ
ACX61_RS14325	COG0523	cobalamin synthesis protein
ACX61_RS14335	COG1607	acyl-coa hydrolase
ACX61_RS14345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_RS14350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACX61_RS14355	COG1309	transcriptional regulator
ACX61_RS14380	COG2040	homocysteine
ACX61_RS14385	COG0531	amino acid
ACX61_RS14440	COG1595	DNA-templated transcription, initiation
ACX61_RS14450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_RS14455	COG0477	Major facilitator Superfamily
ACX61_RS14465	COG0367	asparagine synthase
ACX61_RS14480	COG0405	Gamma-glutamyltransferase
ACX61_RS14485	COG2814	Major facilitator Superfamily
ACX61_RS14495	COG2050	protein possibly involved in aromatic compounds catabolism
ACX61_RS14510	COG1090	epimerase
ACX61_RS14530	COG0420	3'-5' exonuclease activity
ACX61_RS14555	COG0735	belongs to the Fur family
ACX61_RS14560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ACX61_RS14580	COG0121	glutamine amidotransferase
ACX61_RS14595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_RS14605	COG0210	DNA helicase
ACX61_RS14610	COG2885	chlorophyll binding
ACX61_RS14615	COG0204	Acyl-transferase
ACX61_RS14630	COG2894	cell division
ACX61_RS14645	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS14650	COG1674	ftsk spoiiie
ACX61_RS14650	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ACX61_RS14655	COG0492	ferredoxin-NADP+ reductase activity
ACX61_RS14660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ACX61_RS14670	COG0456	acetyltransferase
ACX61_RS14715	COG1981	membrane
ACX61_RS14730	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACX61_RS14730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX61_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS14770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX61_RS14795	COG0564	pseudouridine synthase activity
ACX61_RS14805	COG0358	DNA primase activity
ACX61_RS14820	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ACX61_RS14850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACX61_RS14880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACX61_RS14890	COG0351	phosphomethylpyrimidine kinase
ACX61_RS14890	COG0352	thiamine-phosphate diphosphorylase activity
ACX61_RS14890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACX61_RS14895	COG1652	LysM domain
ACX61_RS14920	COG1399	metal-binding, possibly nucleic acid-binding protein
ACX61_RS14925	COG3101	peptidyl-lysine hydroxylation
ACX61_RS14930	COG0009	L-threonylcarbamoyladenylate synthase
ACX61_RS14935	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACX61_RS14940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACX61_RS14955	COG4106	trans-aconitate 2-methyltransferase activity
ACX61_RS14970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_RS14970	COG0596	Alpha beta hydrolase
ACX61_RS14970	COG2226	methyltransferase
ACX61_RS14975	COG1877	trehalose-phosphatase activity
ACX61_RS14980	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
ACX61_RS14985	COG2223	nitrite transmembrane transporter activity
ACX61_RS15005	COG1196	nuclear chromosome segregation
ACX61_RS15015	COG0730	response to heat
ACX61_RS15030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACX61_RS15040	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX61_RS15090	COG0489	protein tyrosine kinase activity
ACX61_RS15100	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_RS15100	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_RS15130	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ACX61_RS15135	COG2081	HI0933 family
ACX61_RS15145	COG0668	transmembrane transport
ACX61_RS15165	COG0583	DNA-binding transcription factor activity
ACX61_RS15185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACX61_RS15190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX61_RS15220	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ACX61_RS15260	COG0745	RESPONSE REGULATOR receiver
ACX61_RS15280	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACX61_RS15295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ACX61_RS15310	COG0583	DNA-binding transcription factor activity
ACX61_RS15340	COG0583	DNA-binding transcription factor activity
ACX61_RS15355	COG0583	DNA-binding transcription factor activity
ACX61_RS15360	COG1053	succinate dehydrogenase
ACX61_RS15370	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACX61_RS15375	COG2814	Major facilitator Superfamily
ACX61_RS15380	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS15385	COG0583	DNA-binding transcription factor activity
ACX61_RS15390	COG1063	alcohol dehydrogenase
ACX61_RS15420	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACX61_RS15425	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ACX61_RS15430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX61_RS15445	COG3667	copper resistance
ACX61_RS15450	COG2132	Multicopper oxidase
ACX61_RS15460	COG0561	phosphatase activity
ACX61_RS15465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACX61_RS15475	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACX61_RS15490	COG1214	PFAM Peptidase M22, glycoprotease
ACX61_RS15515	COG3328	transposase activity
ACX61_RS15525	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACX61_RS15535	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACX61_RS15540	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACX61_RS15545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACX61_RS15605	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACX61_RS15615	COG1846	Transcriptional regulator
ACX61_RS15620	COG1764	response to oxidative stress
ACX61_RS15660	COG0037	tRNA processing
ACX61_RS15670	COG0248	Ppx GppA phosphatase
ACX61_RS15695	COG0072	phenylalanine-tRNA ligase activity
ACX61_RS15735	COG1238	metal cluster binding
ACX61_RS15740	COG0625	glutathione transferase activity
ACX61_RS15755	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_RS15760	COG3028	Belongs to the UPF0307 family
ACX61_RS15765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACX61_RS15785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACX61_RS15790	COG0617	tRNA 3'-terminal CCA addition
ACX61_RS15795	COG1555	photosystem II stabilization
ACX61_RS15800	COG3956	TIGRFAM MazG family protein
ACX61_RS15810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACX61_RS15830	COG2205	protein histidine kinase activity
ACX61_RS15830	COG0784	Response regulator, receiver
ACX61_RS15830	COG5002	protein histidine kinase activity
ACX61_RS15835	COG1024	Enoyl-CoA hydratase
ACX61_RS15840	COG2084	Dehydrogenase
ACX61_RS15845	COG3622	Belongs to the hyi family
ACX61_RS15875	COG0697	spore germination
ACX61_RS15885	COG2814	Major facilitator Superfamily
ACX61_RS15890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACX61_RS15900	COG0583	DNA-binding transcription factor activity
ACX61_RS15905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACX61_RS15915	COG0084	hydrolase, TatD family'
ACX61_RS15930	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACX61_RS15935	COG2801	Transposase and inactivated derivatives
ACX61_RS15955	COG2130	NADP-dependent
ACX61_RS15960	COG1309	transcriptional regulator
ACX61_RS15970	COG1902	pentaerythritol trinitrate reductase activity
ACX61_RS15980	COG1979	alcohol dehydrogenase
ACX61_RS15990	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ACX61_RS16005	COG0604	alcohol dehydrogenase
ACX61_RS16005	COG3321	synthase
ACX61_RS16010	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ACX61_RS16015	COG0583	DNA-binding transcription factor activity
ACX61_RS16020	COG4221	oxidoreductase activity
ACX61_RS16060	COG2826	transposase and inactivated derivatives, IS30 family
ACX61_RS16085	COG0440	acetolactate synthase activity
ACX61_RS16090	COG0028	Belongs to the TPP enzyme family
ACX61_RS16115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACX61_RS16120	COG1136	(ABC) transporter
ACX61_RS16120	COG0577	efflux transmembrane transporter activity
ACX61_RS16125	COG1538	Outer membrane efflux protein
ACX61_RS16140	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ACX61_RS16145	COG1162	GTPase activity
ACX61_RS16155	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ACX61_RS16195	COG1426	Protein conserved in bacteria
ACX61_RS16230	COG0793	Belongs to the peptidase S41A family
ACX61_RS16245	COG2267	carboxylic ester hydrolase activity
ACX61_RS16255	COG1012	belongs to the aldehyde dehydrogenase family
ACX61_RS16260	COG3265	gluconokinase activity
ACX61_RS16270	COG0800	Aldolase
ACX61_RS16280	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ACX61_RS16285	COG0857	belongs to the CobB CobQ family
ACX61_RS16285	COG0280	phosphate acetyltransferase
ACX61_RS16290	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX61_RS16290	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ACX61_RS16310	COG0740	serine-type endopeptidase activity
ACX61_RS16320	COG4774	siderophore transport
ACX61_RS16330	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACX61_RS16340	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACX61_RS16340	COG2813	Specifically methylates the guanine in position
ACX61_RS16445	COG0788	formyltetrahydrofolate deformylase activity
ACX61_RS16470	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX61_RS16470	COG4651	solute:proton antiporter activity
ACX61_RS16490	COG0724	RNA recognition motif
ACX61_RS16495	COG0210	DNA helicase
ACX61_RS16520	COG1733	regulation of RNA biosynthetic process
ACX61_RS16530	COG2900	Belongs to the SlyX family
ACX61_RS16535	COG0488	(ABC) transporter
ACX61_RS16540	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS16545	COG1560	Kdo2-lipid A biosynthetic process
ACX61_RS16555	COG1301	dicarboxylic acid transport
ACX61_RS16610	COG0473	3-isopropylmalate dehydrogenase activity
ACX61_RS16675	COG0583	DNA-binding transcription factor activity
ACX61_RS16685	COG0625	glutathione transferase activity
ACX61_RS16690	COG2378	regulation of single-species biofilm formation
ACX61_RS16695	COG0546	phosphoglycolate phosphatase activity
ACX61_RS16705	COG1530	ribonuclease E activity
ACX61_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_RS16725	COG0583	DNA-binding transcription factor activity
ACX61_RS16730	COG4221	oxidoreductase activity
ACX61_RS16735	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACX61_RS16745	COG0534	Mate efflux family protein
ACX61_RS16760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACX61_RS16785	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ACX61_RS16785	COG0493	'glutamate synthase
ACX61_RS16795	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ACX61_RS16800	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACX61_RS16815	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ACX61_RS16825	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACX61_RS16825	COG0644	oxidoreductase
ACX61_RS16835	COG0425	Belongs to the sulfur carrier protein TusA family
ACX61_RS16840	COG4535	Mg2 and Co2 transporter CorC
ACX61_RS16850	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACX61_RS16870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACX61_RS16875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ACX61_RS16875	COG0475	glutathione-regulated potassium exporter activity
ACX61_RS16890	COG0484	heat shock protein binding
ACX61_RS16895	COG0789	Transcriptional regulator
ACX61_RS16900	COG0598	Magnesium transport protein CorA
ACX61_RS16915	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ACX61_RS16920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ACX61_RS16925	COG1074	ATP-dependent DNA helicase activity
ACX61_RS16930	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ACX61_RS16950	COG2226	methyltransferase
ACX61_RS16965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ACX61_RS16970	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACX61_RS16985	COG2111	Na H antiporter
ACX61_RS16985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACX61_RS16990	COG1006	Multisubunit Na H antiporter MnhC subunit
ACX61_RS16995	COG0651	ATP synthesis coupled electron transport
ACX61_RS17000	COG1863	multisubunit Na H antiporter MnhE subunit
ACX61_RS17005	COG2212	antiporter activity
ACX61_RS17010	COG1320	monovalent cation:proton antiporter activity
ACX61_RS17025	COG0195	Participates in both transcription termination and antitermination
ACX61_RS17075	COG0237	dephospho-CoA kinase activity
ACX61_RS17085	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACX61_RS17100	COG0497	DNA recombination
ACX61_RS17110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ACX61_RS17140	COG2169	Transcriptional regulator
ACX61_RS17140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACX61_RS17145	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACX61_RS17205	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
ACX61_RS17220	COG0326	Molecular chaperone. Has ATPase activity
ACX61_RS17235	COG2056	Na+-H+ antiporter family
ACX61_RS17240	COG0596	Alpha beta hydrolase
ACX61_RS17255	COG3328	transposase activity
ACX61_RS17340	COG0546	phosphoglycolate phosphatase activity
ACX61_RS17345	COG1716	ATPase activity
ACX61_RS17390	COG0181	hydroxymethylbilane synthase activity
ACX61_RS17400	COG3275	phosphorelay sensor kinase activity
ACX61_RS17420	COG1538	Outer membrane efflux protein
ACX61_RS17425	COG0697	spore germination
ACX61_RS17450	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ACX61_RS17455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACX61_RS17460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACX61_RS17465	COG0772	Belongs to the SEDS family
ACX61_RS17490	COG4974	Belongs to the 'phage' integrase family
ACX61_RS17495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_RS17505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACX61_RS17515	COG2197	response regulator
ACX61_RS17530	COG0793	Belongs to the peptidase S41A family
ACX61_RS17535	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACX61_RS17540	COG0795	lipopolysaccharide-transporting ATPase activity
ACX61_RS17580	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX61_RS17580	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACX61_RS17590	COG0004	ammonium transporteR
ACX61_RS17595	COG0347	Belongs to the P(II) protein family
ACX61_RS17605	COG0606	chelatase, subunit chli
ACX61_RS17635	COG1061	Type III restriction enzyme res subunit
ACX61_RS17655	COG0659	secondary active sulfate transmembrane transporter activity
ACX61_RS17660	COG0589	response to stress
ACX61_RS17700	COG0606	chelatase, subunit chli
ACX61_RS17705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACX61_RS17710	COG0235	Class ii aldolase
ACX61_RS17715	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACX61_RS17730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ACX61_RS17745	COG0318	PFAM AMP-dependent synthetase and ligase
ACX61_RS17755	COG0477	Major facilitator Superfamily
ACX61_RS17760	COG2860	membrane
ACX61_RS17765	COG3012	SEC-C Motif Domain Protein
ACX61_RS17770	COG1253	flavin adenine dinucleotide binding
ACX61_RS17780	COG2814	Major facilitator Superfamily
ACX61_RS17790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ACX61_RS17825	COG0655	NAD(P)H dehydrogenase (quinone) activity
ACX61_RS17835	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACX61_RS17870	COG1309	transcriptional regulator
ACX61_RS17905	COG0758	DNA mediated transformation
ACX61_RS17915	COG0697	spore germination
ACX61_RS17920	COG1309	transcriptional regulator
ACX61_RS17935	COG0386	Belongs to the glutathione peroxidase family
ACX61_RS18005	COG1121	(ABC) transporter
ACX61_RS18010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACX61_RS18015	COG1280	lysine exporter protein (LysE YggA)
ACX61_RS18020	COG2837	iron assimilation
ACX61_RS18030	COG0281	malic enzyme
ACX61_RS18075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACX61_RS18075	COG0519	Catalyzes the synthesis of GMP from XMP
ACX61_RS18080	COG4399	Belongs to the UPF0754 family
ACX61_RS18085	COG2259	Doxx family
ACX61_RS18090	COG0586	Pfam SNARE associated Golgi protein
ACX61_RS18105	COG1192	Involved in chromosome partitioning
ACX61_RS18115	COG0271	Belongs to the BolA IbaG family
ACX61_RS18130	COG0477	Major facilitator Superfamily
ACX61_RS18135	COG1024	Enoyl-CoA hydratase
ACX61_RS18140	COG1024	Enoyl-CoA hydratase
ACX61_RS18145	COG1960	acyl-CoA dehydrogenase activity
ACX61_RS18150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACX61_RS18170	COG1113	amino acid transport
ACX61_RS18175	COG1113	amino acid transport
ACX61_RS18180	COG0251	oxidation-reduction process
ACX61_RS18220	COG0564	pseudouridine synthase activity
ACX61_RS18290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACX61_RS18305	COG1802	Transcriptional regulator
ACX61_RS18310	COG1448	Aminotransferase
ACX61_RS18315	COG0277	FAD linked oxidase domain protein
ACX61_RS18325	COG2186	Transcriptional regulator
ACX61_RS18335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACX61_RS18340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ACX61_RS18355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ACX61_RS18360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACX61_RS18365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACX61_RS18410	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS18415	COG1083	cytidylyl-transferase
ACX61_RS18420	COG0673	inositol 2-dehydrogenase activity
ACX61_RS18425	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACX61_RS18430	COG1045	serine acetyltransferase
ACX61_RS18435	COG2089	acid synthase
ACX61_RS18440	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACX61_RS18445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACX61_RS18455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACX61_RS18460	COG1596	polysaccharide export
ACX61_RS18485	COG0728	peptidoglycan biosynthetic process
ACX61_RS18490	COG3023	N-Acetylmuramoyl-L-alanine amidase
ACX61_RS18545	COG0546	phosphoglycolate phosphatase activity
ACX61_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
ACX61_RS18570	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_RS18575	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ACX61_RS18580	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACX61_RS18590	COG1116	anion transmembrane transporter activity
ACX61_RS18595	COG1309	transcriptional regulator
ACX61_RS18600	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACX61_RS18610	COG0196	riboflavin kinase activity
ACX61_RS18615	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACX61_RS18625	COG1047	Peptidyl-prolyl cis-trans
ACX61_RS18665	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACX61_RS18670	COG0657	acetylesterase activity
ACX61_RS18690	COG0583	DNA-binding transcription factor activity
ACX61_RS18720	COG2951	lytic endotransglycosylase activity
ACX61_RS18725	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACX61_RS18745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACX61_RS18755	COG3328	transposase activity
ACX61_RS18765	COG0671	phosphoesterase, PA-phosphatase related
ACX61_RS18770	COG0861	Integral membrane protein TerC family
ACX61_RS18780	COG0754	glutathionylspermidine amidase activity
ACX61_RS18790	COG0402	S-adenosylhomocysteine deaminase activity
ACX61_RS18810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACX61_RS18815	COG1230	cation diffusion facilitator family transporter
ACX61_RS18830	COG0706	membrane insertase activity
ACX61_RS19165	COG2133	pyrroloquinoline quinone binding
ACX61_RS19255	COG1113	amino acid transport
ACX61_RS20005	COG2233	PERMEase