locus-tag	class	description
CTZ19_RS00010	COG0592	DNA-directed DNA polymerase activity
CTZ19_RS00020	COG0187	DNA topoisomerase II activity
CTZ19_RS00030	COG0586	Pfam SNARE associated Golgi protein
CTZ19_RS00035	COG0488	(ABC) transporter
CTZ19_RS00060	COG0596	Alpha beta hydrolase
CTZ19_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ19_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ19_RS00165	COG2233	PERMEase
CTZ19_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS00215	COG2814	Major facilitator Superfamily
CTZ19_RS00220	COG0656	L-ascorbic acid biosynthetic process
CTZ19_RS00225	COG0583	DNA-binding transcription factor activity
CTZ19_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_RS00245	COG1064	alcohol dehydrogenase
CTZ19_RS00250	COG2818	Glycosylase
CTZ19_RS00265	COG1194	a g-specific adenine glycosylase
CTZ19_RS00285	COG2983	Belongs to the UPF0260 family
CTZ19_RS00290	COG2133	pyrroloquinoline quinone binding
CTZ19_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ19_RS00300	COG2116	formate transmembrane transporter activity
CTZ19_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_RS00325	COG1335	isochorismatase
CTZ19_RS00330	COG0385	Bile acid
CTZ19_RS00335	COG0534	Mate efflux family protein
CTZ19_RS00340	COG1683	Conserved Protein
CTZ19_RS00360	COG0625	glutathione transferase activity
CTZ19_RS00370	COG1113	amino acid transport
CTZ19_RS00380	COG0523	cobalamin synthesis protein
CTZ19_RS00390	COG2188	Transcriptional regulator
CTZ19_RS00420	COG0010	Belongs to the arginase family
CTZ19_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ19_RS00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ19_RS00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ19_RS00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTZ19_RS00560	COG0534	Mate efflux family protein
CTZ19_RS00565	COG0436	Aminotransferase
CTZ19_RS00570	COG2733	membrane
CTZ19_RS00585	COG2918	glutathione biosynthetic process
CTZ19_RS00600	COG1388	LysM domain
CTZ19_RS00600	COG0791	NLP P60 protein
CTZ19_RS00615	COG3150	esterase
CTZ19_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ19_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_RS00650	COG2233	PERMEase
CTZ19_RS00655	COG2351	hydroxyisourate hydrolase activity
CTZ19_RS00690	COG3706	GGDEF domain
CTZ19_RS00705	COG1393	Belongs to the ArsC family
CTZ19_RS00710	COG0708	Exodeoxyribonuclease III
CTZ19_RS00730	COG0189	ligase activity
CTZ19_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ19_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ19_RS00775	COG4942	peptidase
CTZ19_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ19_RS00795	COG2119	membrane
CTZ19_RS00800	COG4774	siderophore transport
CTZ19_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_RS00805	COG0426	domain, Protein
CTZ19_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ19_RS00850	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_RS00855	COG1519	Transferase
CTZ19_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ19_RS00865	COG0668	transmembrane transport
CTZ19_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_RS00885	COG1335	isochorismatase
CTZ19_RS00890	COG1522	sequence-specific DNA binding
CTZ19_RS00895	COG3328	transposase activity
CTZ19_RS00920	COG2198	Histidine kinase
CTZ19_RS00920	COG2205	protein histidine kinase activity
CTZ19_RS00920	COG0784	Response regulator, receiver
CTZ19_RS00925	COG3162	membrane
CTZ19_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ19_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_RS00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ19_RS00965	COG1309	transcriptional regulator
CTZ19_RS00985	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_RS00985	COG0351	phosphomethylpyrimidine kinase
CTZ19_RS00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ19_RS00995	COG2814	Major facilitator Superfamily
CTZ19_RS01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ19_RS01020	COG1113	amino acid transport
CTZ19_RS01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ19_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS01045	COG1335	isochorismatase
CTZ19_RS01075	COG2814	Major facilitator Superfamily
CTZ19_RS01080	COG0583	DNA-binding transcription factor activity
CTZ19_RS01100	COG0667	Aldo Keto reductase
CTZ19_RS01135	COG1733	regulation of RNA biosynthetic process
CTZ19_RS01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_RS01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ19_RS01225	COG2329	Antibiotic biosynthesis monooxygenase
CTZ19_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ19_RS01285	COG0427	acetyl-CoA hydrolase
CTZ19_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_RS01315	COG4221	oxidoreductase activity
CTZ19_RS01320	COG2873	o-acetylhomoserine
CTZ19_RS01325	COG0488	(ABC) transporter
CTZ19_RS01410	COG0833	amino acid
CTZ19_RS01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ19_RS01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ19_RS01475	COG2226	methyltransferase
CTZ19_RS01525	COG0067	glutamate synthase
CTZ19_RS01525	COG0070	glutamate synthase
CTZ19_RS01525	COG0069	glutamate synthase activity
CTZ19_RS01530	COG0493	'glutamate synthase
CTZ19_RS01540	COG1704	LemA family
CTZ19_RS01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ19_RS01565	COG3307	-O-antigen
CTZ19_RS01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ19_RS01595	COG0194	GDP metabolic process
CTZ19_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ19_RS01665	COG5380	lipid catabolic process
CTZ19_RS01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ19_RS01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ19_RS01700	COG0277	FAD linked oxidase domain protein
CTZ19_RS01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTZ19_RS01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_RS01730	COG1289	transmembrane transporter activity
CTZ19_RS01740	COG0628	permease
CTZ19_RS01745	COG1192	Involved in chromosome partitioning
CTZ19_RS01775	COG0833	amino acid
CTZ19_RS01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ19_RS01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ19_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS01835	COG0583	DNA-binding transcription factor activity
CTZ19_RS01880	COG0517	IMP dehydrogenase activity
CTZ19_RS01885	COG1983	PspC domain protein
CTZ19_RS01895	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS01910	COG0408	coproporphyrinogen oxidase activity
CTZ19_RS01930	COG0513	Belongs to the DEAD box helicase family
CTZ19_RS01935	COG1127	ABC transporter
CTZ19_RS01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ19_RS01950	COG2854	intermembrane phospholipid transfer
CTZ19_RS01960	COG0598	Magnesium transport protein CorA
CTZ19_RS01970	COG0494	nUDIX hydrolase
CTZ19_RS01975	COG1040	competence protein
CTZ19_RS01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ19_RS02000	COG1946	Acyl-CoA thioesterase
CTZ19_RS02005	COG1301	dicarboxylic acid transport
CTZ19_RS02020	COG1959	2 iron, 2 sulfur cluster binding
CTZ19_RS02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_RS02025	COG1017	nitric oxide dioxygenase activity
CTZ19_RS02030	COG0433	COG0433 Predicted ATPase
CTZ19_RS02035	COG0626	cystathionine gamma-synthase activity
CTZ19_RS02190	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ19_RS02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ19_RS02230	COG0339	signal peptide processing
CTZ19_RS02235	COG0557	exoribonuclease II activity
CTZ19_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ19_RS02285	COG2169	Transcriptional regulator
CTZ19_RS02290	COG0697	spore germination
CTZ19_RS02295	COG1295	ribonuclease BN
CTZ19_RS02330	COG1702	phosphate starvation-inducible protein PhoH
CTZ19_RS02340	COG0739	heme binding
CTZ19_RS02340	COG1196	nuclear chromosome segregation
CTZ19_RS02340	COG0741	lytic transglycosylase activity
CTZ19_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ19_RS02375	COG1183	phosphatidylcholine synthase activity
CTZ19_RS02420	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS02425	COG1309	transcriptional regulator
CTZ19_RS02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ19_RS02445	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS02465	COG2969	positive regulation of protein catabolic process
CTZ19_RS02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ19_RS02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ19_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ19_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ19_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ19_RS02530	COG1408	metallophosphoesterase
CTZ19_RS02540	COG2199	diguanylate cyclase activity
CTZ19_RS02600	COG1607	acyl-coa hydrolase
CTZ19_RS02630	COG2350	Protein conserved in bacteria
CTZ19_RS02640	COG0613	PHP domain protein
CTZ19_RS02645	COG3781	membrane
CTZ19_RS02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ19_RS02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ19_RS02670	COG1862	Preprotein translocase
CTZ19_RS02720	COG0629	single-stranded DNA binding
CTZ19_RS02790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ19_RS02930	COG4695	Portal protein
CTZ19_RS02940	COG2205	protein histidine kinase activity
CTZ19_RS02945	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ19_RS02965	COG0726	polysaccharide deacetylase
CTZ19_RS02970	COG0463	Glycosyl transferase, family 2
CTZ19_RS02975	COG0438	transferase activity, transferring glycosyl groups
CTZ19_RS03040	COG0625	glutathione transferase activity
CTZ19_RS03045	COG0583	DNA-binding transcription factor activity
CTZ19_RS03050	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS03055	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS03065	COG2205	protein histidine kinase activity
CTZ19_RS03070	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS03075	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ19_RS03095	COG2096	Adenosyltransferase
CTZ19_RS03145	COG0285	dihydrofolate synthase activity
CTZ19_RS03165	COG0450	alkyl hydroperoxide reductase
CTZ19_RS03180	COG0477	Major facilitator Superfamily
CTZ19_RS03185	COG1272	protein, Hemolysin III
CTZ19_RS03215	COG0183	Belongs to the thiolase family
CTZ19_RS03220	COG2207	Transcriptional regulator
CTZ19_RS03240	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_RS03260	COG0183	Belongs to the thiolase family
CTZ19_RS03270	COG2885	chlorophyll binding
CTZ19_RS03270	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTZ19_RS03280	COG1690	Belongs to the RtcB family
CTZ19_RS03285	COG0833	amino acid
CTZ19_RS03295	COG2233	PERMEase
CTZ19_RS03300	COG1217	gtp-binding protein TYPA
CTZ19_RS03325	COG2094	Belongs to the DNA glycosylase MPG family
CTZ19_RS03330	COG4772	TonB-dependent receptor
CTZ19_RS03345	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_RS03350	COG0679	Auxin Efflux Carrier
CTZ19_RS03360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_RS03365	COG0354	folic acid binding
CTZ19_RS03375	COG3189	MarR family transcriptional regulator
CTZ19_RS03380	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ19_RS03385	COG3422	double-strand break repair
CTZ19_RS03425	COG0840	transmembrane signaling receptor activity
CTZ19_RS03445	COG5510	response to toxic substance
CTZ19_RS03455	COG2832	Protein of unknown function (DUF454)
CTZ19_RS03460	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ19_RS03500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ19_RS03510	COG1289	transmembrane transporter activity
CTZ19_RS03515	COG2814	Major facilitator Superfamily
CTZ19_RS03535	COG1115	amino acid carrier protein
CTZ19_RS03540	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ19_RS03545	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ19_RS03550	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ19_RS03580	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ19_RS03590	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ19_RS03595	COG1077	Cell shape determining protein MreB Mrl
CTZ19_RS03600	COG1792	Involved in formation and maintenance of cell shape
CTZ19_RS03605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ19_RS03610	COG0424	maF-like protein
CTZ19_RS03615	COG1530	ribonuclease E activity
CTZ19_RS03625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_RS03635	COG0560	Phosphoserine phosphatase
CTZ19_RS03645	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_RS03670	COG2207	Transcriptional regulator
CTZ19_RS03690	COG1113	amino acid transport
CTZ19_RS03695	COG2828	Protein conserved in bacteria
CTZ19_RS03700	COG0142	geranyltranstransferase activity
CTZ19_RS03705	COG2315	Protein conserved in bacteria
CTZ19_RS03720	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ19_RS03740	COG2194	sulfuric ester hydrolase activity
CTZ19_RS03745	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS03750	COG0642	Histidine kinase
CTZ19_RS03760	COG0004	ammonium transporteR
CTZ19_RS03770	COG0583	DNA-binding transcription factor activity
CTZ19_RS03790	COG0525	valine-tRNA ligase activity
CTZ19_RS03800	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS03810	COG0393	Putative heavy-metal-binding
CTZ19_RS03815	COG0393	Putative heavy-metal-binding
CTZ19_RS03820	COG1538	Outer membrane efflux protein
CTZ19_RS03830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS03835	COG0671	phosphoesterase, PA-phosphatase related
CTZ19_RS03865	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ19_RS03880	COG1648	precorrin-2 dehydrogenase activity
CTZ19_RS03880	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ19_RS03885	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ19_RS03890	COG1733	regulation of RNA biosynthetic process
CTZ19_RS03900	COG0531	amino acid
CTZ19_RS03915	COG0321	lipoyl(octanoyl) transferase activity
CTZ19_RS03920	COG2921	Belongs to the UPF0250 family
CTZ19_RS03960	COG2009	succinate dehydrogenase
CTZ19_RS03965	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ19_RS03970	COG1053	succinate dehydrogenase
CTZ19_RS03975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ19_RS04000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_RS04020	COG2354	Protein conserved in bacteria
CTZ19_RS04025	COG2321	neutral zinc metallopeptidase
CTZ19_RS04070	COG2843	Capsule synthesis protein
CTZ19_RS04085	COG0589	response to stress
CTZ19_RS04105	COG0505	Belongs to the CarA family
CTZ19_RS04130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ19_RS04135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ19_RS04185	COG0477	Major facilitator Superfamily
CTZ19_RS04190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ19_RS04205	COG1597	lipid kinase activity
CTZ19_RS04210	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ19_RS04240	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ19_RS04260	COG0741	lytic transglycosylase activity
CTZ19_RS04285	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ19_RS04300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_RS04330	COG0778	Nitroreductase
CTZ19_RS04345	COG1929	Belongs to the glycerate kinase type-1 family
CTZ19_RS04350	COG0243	molybdopterin cofactor binding
CTZ19_RS04355	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTZ19_RS04360	COG3339	Conserved Protein
CTZ19_RS04370	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ19_RS04385	COG1113	amino acid transport
CTZ19_RS04395	COG0019	diaminopimelate decarboxylase activity
CTZ19_RS04405	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS04410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ19_RS04440	COG0463	Glycosyl transferase, family 2
CTZ19_RS04460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS04490	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ19_RS04495	COG1136	(ABC) transporter
CTZ19_RS04500	COG2333	competence protein COMEC
CTZ19_RS04500	COG0658	competence protein
CTZ19_RS04510	COG0616	signal peptide processing
CTZ19_RS04510	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ19_RS04515	COG0596	Alpha beta hydrolase
CTZ19_RS04520	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ19_RS04530	COG0628	permease
CTZ19_RS04565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ19_RS04585	COG0823	Involved in the tonB-independent uptake of proteins
CTZ19_RS04605	COG0824	Thioesterase
CTZ19_RS04610	COG1473	amidohydrolase
CTZ19_RS04630	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ19_RS04630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ19_RS04635	COG2814	Major facilitator Superfamily
CTZ19_RS04645	COG1024	Enoyl-CoA hydratase
CTZ19_RS04650	COG1051	belongs to the nudix hydrolase family
CTZ19_RS04650	COG1056	cytidyltransferase-related domain
CTZ19_RS04660	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ19_RS04675	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ19_RS04690	COG4625	pathogenesis
CTZ19_RS04695	COG0583	DNA-binding transcription factor activity
CTZ19_RS04700	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ19_RS04705	COG4208	sulfate ABC transporter
CTZ19_RS04710	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTZ19_RS04720	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ19_RS04725	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTZ19_RS04730	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ19_RS04750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ19_RS04765	COG0681	Belongs to the peptidase S26 family
CTZ19_RS04780	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ19_RS04790	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ19_RS04795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ19_RS04805	COG4221	oxidoreductase activity
CTZ19_RS04835	COG0436	Aminotransferase
CTZ19_RS04855	COG0556	nucleotide-excision repair
CTZ19_RS05050	COG5410	chromosome segregation
CTZ19_RS05240	COG2070	2-Nitropropane dioxygenase
CTZ19_RS05270	COG1215	transferase activity, transferring glycosyl groups
CTZ19_RS05285	COG0415	Belongs to the DNA photolyase family
CTZ19_RS05295	COG1252	NADH dehydrogenase
CTZ19_RS05300	COG1686	Belongs to the peptidase S11 family
CTZ19_RS05315	COG1187	pseudouridine synthase activity
CTZ19_RS05340	COG0477	Major facilitator Superfamily
CTZ19_RS05345	COG0583	DNA-binding transcription factor activity
CTZ19_RS05350	COG1823	symporter activity
CTZ19_RS05360	COG0612	Peptidase, M16
CTZ19_RS05385	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_RS05420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_RS05435	COG1309	transcriptional regulator
CTZ19_RS05445	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ19_RS05450	COG0076	glutamate decarboxylase activity
CTZ19_RS05460	COG1522	sequence-specific DNA binding
CTZ19_RS05465	COG3961	Belongs to the TPP enzyme family
CTZ19_RS05470	COG1113	amino acid transport
CTZ19_RS05475	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ19_RS05480	COG0573	inorganic phosphate transmembrane transporter activity
CTZ19_RS05490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ19_RS05495	COG0616	signal peptide processing
CTZ19_RS05530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ19_RS05535	COG1686	Belongs to the peptidase S11 family
CTZ19_RS05560	COG0583	DNA-binding transcription factor activity
CTZ19_RS05565	COG1067	ATP-dependent peptidase activity
CTZ19_RS05610	COG1966	Carbon starvation protein
CTZ19_RS05615	COG2879	small protein
CTZ19_RS05650	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTZ19_RS05650	COG2508	Transcriptional regulator
CTZ19_RS05670	COG1113	amino acid transport
CTZ19_RS05675	COG0583	DNA-binding transcription factor activity
CTZ19_RS05680	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_RS05685	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_RS05695	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS05700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_RS05705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_RS05705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTZ19_RS05740	COG2814	Major facilitator Superfamily
CTZ19_RS05745	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ19_RS05755	COG1309	transcriptional regulator
CTZ19_RS05775	COG1741	Belongs to the pirin family
CTZ19_RS05785	COG2964	Protein conserved in bacteria
CTZ19_RS05800	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_RS05805	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ19_RS05810	COG4605	iron ion homeostasis
CTZ19_RS05815	COG4604	ABC transporter, ATP-binding protein
CTZ19_RS05820	COG4607	ABC-type enterochelin transport system periplasmic component
CTZ19_RS05825	COG4774	siderophore transport
CTZ19_RS05835	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ19_RS05840	COG1021	2,3-dihydroxybenzoate-AMP ligase
CTZ19_RS05845	COG3433	isochorismatase activity
CTZ19_RS05845	COG1535	isochorismatase
CTZ19_RS05860	COG1132	(ABC) transporter
CTZ19_RS05865	COG1132	(ABC) transporter
CTZ19_RS05870	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTZ19_RS05880	COG1169	isochorismate synthase
CTZ19_RS05895	COG3739	integral membrane protein
CTZ19_RS05920	COG0302	gtp cyclohydrolase
CTZ19_RS05930	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ19_RS05960	COG0308	aminopeptidase N
CTZ19_RS05965	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ19_RS05980	COG0174	glutamine synthetase
CTZ19_RS05990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ19_RS06025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ19_RS06030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ19_RS06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ19_RS06055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ19_RS06060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ19_RS06065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ19_RS06080	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS06085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ19_RS06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_RS06100	COG2223	nitrite transmembrane transporter activity
CTZ19_RS06110	COG0024	Methionine aminopeptidase
CTZ19_RS06115	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ19_RS06130	COG2207	Transcriptional regulator
CTZ19_RS06155	COG2951	lytic endotransglycosylase activity
CTZ19_RS06160	COG0772	Belongs to the SEDS family
CTZ19_RS06175	COG0842	Transport permease protein
CTZ19_RS06180	COG1131	(ABC) transporter
CTZ19_RS06225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS06240	COG4215	(ABC) transporter
CTZ19_RS06245	COG4160	amino acid transport
CTZ19_RS06250	COG4598	ABC transporter
CTZ19_RS06260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ19_RS06265	COG0826	peptidase U32
CTZ19_RS06270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_RS06285	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ19_RS06295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTZ19_RS06310	COG0642	Histidine kinase
CTZ19_RS06320	COG0494	nUDIX hydrolase
CTZ19_RS06330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ19_RS06335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ19_RS06340	COG3139	Protein of unknown function (DUF1315)
CTZ19_RS06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ19_RS06355	COG1301	dicarboxylic acid transport
CTZ19_RS06360	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS06365	COG2819	hydrolase of the alpha beta superfamily
CTZ19_RS06375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ19_RS06385	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTZ19_RS06390	COG1234	tRNA 3'-trailer cleavage
CTZ19_RS06420	COG2363	Small membrane protein
CTZ19_RS06440	COG0513	Belongs to the DEAD box helicase family
CTZ19_RS06450	COG0778	Nitroreductase
CTZ19_RS06480	COG1286	toxin biosynthetic process
CTZ19_RS06505	COG4783	chaperone-mediated protein folding
CTZ19_RS06510	COG1610	YqeY-like protein
CTZ19_RS06610	COG3111	PFAM Bacterial OB fold (BOF) protein
CTZ19_RS06635	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTZ19_RS06640	COG0786	glutamate:sodium symporter activity
CTZ19_RS06650	COG2186	Transcriptional regulator
CTZ19_RS06700	COG0477	Major facilitator Superfamily
CTZ19_RS06730	COG2985	domain, Protein
CTZ19_RS06740	COG2995	paraquat-inducible protein a
CTZ19_RS06765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_RS06770	COG2011	ABC-type metal ion transport system permease component
CTZ19_RS06775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ19_RS06780	COG1464	Belongs to the NlpA lipoprotein family
CTZ19_RS06785	COG0151	Belongs to the GarS family
CTZ19_RS06790	COG0138	bifunctional purine biosynthesis protein purh
CTZ19_RS06795	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ19_RS06825	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ19_RS06835	COG1305	Transglutaminase-like
CTZ19_RS06845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ19_RS06850	COG0305	Participates in initiation and elongation during chromosome replication
CTZ19_RS06875	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ19_RS06885	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ19_RS06890	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ19_RS06915	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ19_RS06915	COG0726	polysaccharide deacetylase
CTZ19_RS06920	COG1215	transferase activity, transferring glycosyl groups
CTZ19_RS06935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_RS06955	COG0583	DNA-binding transcription factor activity
CTZ19_RS06975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_RS06980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_RS06995	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS07000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_RS07005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_RS07030	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTZ19_RS07035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ19_RS07045	COG2205	protein histidine kinase activity
CTZ19_RS07050	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS07055	COG0174	glutamine synthetase
CTZ19_RS07075	COG0729	surface antigen
CTZ19_RS07105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ19_RS07110	COG2814	Major facilitator Superfamily
CTZ19_RS07125	COG0583	DNA-binding transcription factor activity
CTZ19_RS07140	COG1187	pseudouridine synthase activity
CTZ19_RS07160	COG0802	atpase or kinase
CTZ19_RS07165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ19_RS07175	COG1923	regulation of RNA biosynthetic process
CTZ19_RS07180	COG0697	spore germination
CTZ19_RS07195	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_RS07205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ19_RS07210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ19_RS07210	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ19_RS07215	COG4302	ethanolamine ammonia-lyase activity
CTZ19_RS07220	COG4303	Ethanolamine ammonia lyase large subunit
CTZ19_RS07225	COG0531	amino acid
CTZ19_RS07245	COG1454	alcohol dehydrogenase
CTZ19_RS07250	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ19_RS07260	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTZ19_RS07280	COG0308	aminopeptidase N
CTZ19_RS07290	COG4221	oxidoreductase activity
CTZ19_RS07300	COG1605	Chorismate mutase
CTZ19_RS07320	COG1309	transcriptional regulator
CTZ19_RS07330	COG0668	transmembrane transport
CTZ19_RS07365	COG4773	Receptor
CTZ19_RS07385	COG0488	(ABC) transporter
CTZ19_RS07390	COG0589	response to stress
CTZ19_RS07410	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ19_RS07420	COG3135	benzoate transporter
CTZ19_RS07425	COG1522	sequence-specific DNA binding
CTZ19_RS07435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ19_RS07440	COG0583	DNA-binding transcription factor activity
CTZ19_RS07450	COG0183	Belongs to the thiolase family
CTZ19_RS07460	COG2030	dehydratase
CTZ19_RS07465	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ19_RS07480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTZ19_RS07490	COG0824	Thioesterase
CTZ19_RS07495	COG1454	alcohol dehydrogenase
CTZ19_RS07505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ19_RS07525	COG0069	glutamate synthase activity
CTZ19_RS07685	COG5410	chromosome segregation
CTZ19_RS07810	COG0739	heme binding
CTZ19_RS07880	COG2814	Major facilitator Superfamily
CTZ19_RS07895	COG0511	ligase activity, forming carbon-carbon bonds
CTZ19_RS07915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_RS07915	COG1116	anion transmembrane transporter activity
CTZ19_RS07920	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS07930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_RS07930	COG2146	nitrite reductase [NAD(P)H] activity
CTZ19_RS07935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_RS07940	COG0243	molybdopterin cofactor binding
CTZ19_RS07950	COG0243	molybdopterin cofactor binding
CTZ19_RS07955	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ19_RS07970	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ19_RS07970	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ19_RS07975	COG0303	'Molybdopterin
CTZ19_RS07985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_RS07990	COG0697	spore germination
CTZ19_RS08010	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ19_RS08015	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ19_RS08075	COG2204	response regulator
CTZ19_RS08080	COG3852	Histidine kinase
CTZ19_RS08100	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ19_RS08105	COG0575	Belongs to the CDS family
CTZ19_RS08140	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_RS08155	COG2137	regulation of response to DNA damage stimulus
CTZ19_RS08165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ19_RS08170	COG1011	Hydrolase
CTZ19_RS08195	COG1522	sequence-specific DNA binding
CTZ19_RS08205	COG1113	amino acid transport
CTZ19_RS08225	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_RS08230	COG2135	peptidase activity
CTZ19_RS08245	COG3300	MHYT domain
CTZ19_RS08245	COG5001	Diguanylate cyclase
CTZ19_RS08265	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTZ19_RS08265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ19_RS08265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ19_RS08270	COG1105	Belongs to the carbohydrate kinase PfkB family
CTZ19_RS08275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ19_RS08275	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ19_RS08305	COG0024	Methionine aminopeptidase
CTZ19_RS08310	COG0583	DNA-binding transcription factor activity
CTZ19_RS08320	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ19_RS08325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ19_RS08330	COG0516	GMP reductase activity
CTZ19_RS08330	COG0517	IMP dehydrogenase activity
CTZ19_RS08355	COG0552	protein localization to endoplasmic reticulum
CTZ19_RS08365	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTZ19_RS08380	COG4890	Cyd operon protein YbgT
CTZ19_RS08385	COG1294	oxidase, subunit
CTZ19_RS08405	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ19_RS08415	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ19_RS08420	COG4774	siderophore transport
CTZ19_RS08435	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ19_RS08440	COG0569	domain protein
CTZ19_RS08445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ19_RS08475	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ19_RS08480	COG0542	response to heat
CTZ19_RS08505	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_RS08505	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_RS08550	COG2323	membrane
CTZ19_RS08555	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTZ19_RS08565	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_RS08570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_RS08575	COG0183	Belongs to the thiolase family
CTZ19_RS08580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ19_RS08585	COG0596	Alpha beta hydrolase
CTZ19_RS08590	COG2271	Major facilitator Superfamily
CTZ19_RS08595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ19_RS08600	COG3485	protocatechuate 3,4-dioxygenase
CTZ19_RS08605	COG3485	protocatechuate 3,4-dioxygenase
CTZ19_RS08610	COG0710	3-dehydroquinate dehydratase activity
CTZ19_RS08615	COG3420	alginic acid biosynthetic process
CTZ19_RS08620	COG3659	wide pore channel activity
CTZ19_RS08625	COG4993	Dehydrogenase
CTZ19_RS08635	COG2391	methyltransferase activity
CTZ19_RS08650	COG1414	Transcriptional regulator
CTZ19_RS08655	COG0583	DNA-binding transcription factor activity
CTZ19_RS08660	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS08685	COG2814	Major facilitator Superfamily
CTZ19_RS08695	COG0154	amidase activity
CTZ19_RS08715	COG4638	Rieske (2fe-2S)
CTZ19_RS08725	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS08735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_RS08745	COG3733	amine oxidase
CTZ19_RS08755	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS08765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_RS08770	COG0183	Belongs to the thiolase family
CTZ19_RS08775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_RS08780	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_RS08790	COG4829	muconolactone delta-isomerase
CTZ19_RS08795	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ19_RS08800	COG0583	DNA-binding transcription factor activity
CTZ19_RS08810	COG2186	Transcriptional regulator
CTZ19_RS08830	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS08850	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS08855	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS08860	COG3829	transcription factor binding
CTZ19_RS08870	COG3162	membrane
CTZ19_RS08885	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS08900	COG0753	catalase activity
CTZ19_RS08925	COG1846	Transcriptional regulator
CTZ19_RS08930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_RS08930	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_RS08940	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTZ19_RS08970	COG1309	transcriptional regulator
CTZ19_RS08980	COG1335	isochorismatase
CTZ19_RS08985	COG0583	DNA-binding transcription factor activity
CTZ19_RS08995	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_RS08995	COG0475	glutathione-regulated potassium exporter activity
CTZ19_RS09005	COG1473	amidohydrolase
CTZ19_RS09020	COG2831	hemolysin activation secretion protein
CTZ19_RS09025	COG3210	domain, Protein
CTZ19_RS09055	COG2188	Transcriptional regulator
CTZ19_RS09070	COG0583	DNA-binding transcription factor activity
CTZ19_RS09100	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ19_RS09120	COG1566	PFAM secretion protein HlyD family protein
CTZ19_RS09135	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS09140	COG0129	dihydroxy-acid dehydratase activity
CTZ19_RS09150	COG0583	DNA-binding transcription factor activity
CTZ19_RS09155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ19_RS09165	COG2084	Dehydrogenase
CTZ19_RS09170	COG2207	Transcriptional regulator
CTZ19_RS09185	COG1064	alcohol dehydrogenase
CTZ19_RS09195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ19_RS09200	COG1120	ATPase activity
CTZ19_RS09220	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ19_RS09340	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ19_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS09410	COG2207	Transcriptional regulator
CTZ19_RS09420	COG2205	protein histidine kinase activity
CTZ19_RS09425	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS09435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS09440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ19_RS09445	COG1538	Outer membrane efflux protein
CTZ19_RS09455	COG2072	flavoprotein involved in K transport
CTZ19_RS09475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_RS09495	COG3539	Fimbrial protein
CTZ19_RS09525	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ19_RS09535	COG0753	catalase activity
CTZ19_RS09550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ19_RS09615	COG3433	isochorismatase activity
CTZ19_RS09615	COG1535	isochorismatase
CTZ19_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS09625	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ19_RS09630	COG4149	molybdate abc transporter
CTZ19_RS09635	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTZ19_RS09645	COG4638	Rieske (2fe-2S)
CTZ19_RS09650	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ19_RS09655	COG0543	2 iron, 2 sulfur cluster binding
CTZ19_RS09655	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS09695	COG2207	Transcriptional regulator
CTZ19_RS09705	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS09710	COG2610	gluconate transmembrane transporter activity
CTZ19_RS09720	COG0583	DNA-binding transcription factor activity
CTZ19_RS09730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_RS09735	COG2031	fatty acid transporter
CTZ19_RS09740	COG0183	Belongs to the thiolase family
CTZ19_RS09745	COG0583	DNA-binding transcription factor activity
CTZ19_RS09750	COG0583	DNA-binding transcription factor activity
CTZ19_RS09765	COG1027	Aspartate ammonia-lyase
CTZ19_RS09775	COG0477	Major facilitator Superfamily
CTZ19_RS09795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_RS09800	COG4521	taurine ABC transporter
CTZ19_RS09815	COG2188	Transcriptional regulator
CTZ19_RS09825	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ19_RS09830	COG1733	regulation of RNA biosynthetic process
CTZ19_RS09835	COG3708	Transcriptional regulator
CTZ19_RS09835	COG2207	Transcriptional regulator
CTZ19_RS09850	COG0730	response to heat
CTZ19_RS09860	COG3453	Protein conserved in bacteria
CTZ19_RS09860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_RS09870	COG3781	membrane
CTZ19_RS09875	COG1063	alcohol dehydrogenase
CTZ19_RS09885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ19_RS09890	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ19_RS09895	COG0022	dehydrogenase e1 component
CTZ19_RS09900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTZ19_RS09905	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ19_RS09920	COG3706	GGDEF domain
CTZ19_RS09935	COG0133	tryptophan synthase activity
CTZ19_RS09945	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ19_RS09980	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ19_RS10005	COG2226	methyltransferase
CTZ19_RS10060	COG0842	Transport permease protein
CTZ19_RS10065	COG0842	Transport permease protein
CTZ19_RS10070	COG1131	(ABC) transporter
CTZ19_RS10085	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ19_RS10090	COG4773	Receptor
CTZ19_RS10110	COG0730	response to heat
CTZ19_RS10115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ19_RS10135	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ19_RS10195	COG4264	IucA IucC family
CTZ19_RS10200	COG4264	IucA IucC family
CTZ19_RS10220	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTZ19_RS10235	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS10240	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS10245	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ19_RS10250	COG2207	Transcriptional regulator
CTZ19_RS10255	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ19_RS10260	COG0776	regulation of translation
CTZ19_RS10285	COG0822	iron-sulfur transferase activity
CTZ19_RS10290	COG0316	Belongs to the HesB IscA family
CTZ19_RS10320	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ19_RS10340	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ19_RS10345	COG0702	epimerase
CTZ19_RS10380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ19_RS10390	COG0339	signal peptide processing
CTZ19_RS10435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ19_RS10440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ19_RS10470	COG0776	regulation of translation
CTZ19_RS10535	COG0084	hydrolase, TatD family'
CTZ19_RS10555	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ19_RS10560	COG1132	(ABC) transporter
CTZ19_RS10570	COG0811	peptide transport
CTZ19_RS10575	COG1475	DNA binding
CTZ19_RS10580	COG1192	Involved in chromosome partitioning
CTZ19_RS10590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ19_RS10605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ19_RS10610	COG0191	fructose-bisphosphate aldolase activity
CTZ19_RS10630	COG0424	maF-like protein
CTZ19_RS10635	COG2850	peptidyl-arginine hydroxylation
CTZ19_RS10645	COG0640	Transcriptional regulator
CTZ19_RS10655	COG3619	membrane
CTZ19_RS10660	COG3122	Protein conserved in bacteria
CTZ19_RS10665	COG1132	(ABC) transporter
CTZ19_RS10685	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ19_RS10690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ19_RS10700	COG0506	proline dehydrogenase activity
CTZ19_RS10700	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ19_RS10700	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ19_RS10705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTZ19_RS10720	COG3698	Phosphodiester glycosidase
CTZ19_RS10730	COG2353	YceI-like domain
CTZ19_RS10740	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ19_RS10785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ19_RS10785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ19_RS10810	COG3539	Fimbrial protein
CTZ19_RS10815	COG3121	Chaperone
CTZ19_RS10845	COG0697	spore germination
CTZ19_RS10855	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ19_RS10865	COG0583	DNA-binding transcription factor activity
CTZ19_RS10885	COG1309	transcriptional regulator
CTZ19_RS10910	COG1522	sequence-specific DNA binding
CTZ19_RS10920	COG1126	abc transporter atp-binding protein
CTZ19_RS10925	COG0765	amino acid transport
CTZ19_RS10930	COG0765	amino acid transport
CTZ19_RS10960	COG1464	Belongs to the NlpA lipoprotein family
CTZ19_RS10970	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ19_RS10975	COG2011	ABC-type metal ion transport system permease component
CTZ19_RS10980	COG0012	GTP binding
CTZ19_RS11005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ19_RS11045	COG0386	Belongs to the glutathione peroxidase family
CTZ19_RS11055	COG0436	Aminotransferase
CTZ19_RS11095	COG3634	alkyl hydroperoxide reductase activity
CTZ19_RS11110	COG0583	DNA-binding transcription factor activity
CTZ19_RS11115	COG0798	PFAM Bile acid sodium symporter
CTZ19_RS11120	COG0640	Transcriptional regulator
CTZ19_RS11135	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTZ19_RS11145	COG0583	DNA-binding transcription factor activity
CTZ19_RS11155	COG1953	Uracil, thiamine, allantoin
CTZ19_RS11165	COG2175	clavaminate synthase activity
CTZ19_RS11170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_RS11175	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTZ19_RS11180	COG4521	taurine ABC transporter
CTZ19_RS11190	COG0477	Major facilitator Superfamily
CTZ19_RS11215	COG1271	oxidase subunit
CTZ19_RS11220	COG1294	oxidase, subunit
CTZ19_RS11230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_RS11250	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTZ19_RS11270	COG3052	prosthetic group binding
CTZ19_RS11275	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTZ19_RS11285	COG2814	Major facilitator Superfamily
CTZ19_RS11305	COG1346	cytolysis
CTZ19_RS11315	COG0583	DNA-binding transcription factor activity
CTZ19_RS11320	COG0625	glutathione transferase activity
CTZ19_RS11325	COG0625	glutathione transferase activity
CTZ19_RS11330	COG0583	DNA-binding transcription factor activity
CTZ19_RS11345	COG1045	serine acetyltransferase
CTZ19_RS11350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ19_RS11355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ19_RS11365	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS11380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_RS11385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_RS11390	COG1126	abc transporter atp-binding protein
CTZ19_RS11395	COG0765	amino acid transport
CTZ19_RS11400	COG0765	amino acid transport
CTZ19_RS11420	COG2205	protein histidine kinase activity
CTZ19_RS11420	COG0784	Response regulator, receiver
CTZ19_RS11440	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ19_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS11505	COG0583	DNA-binding transcription factor activity
CTZ19_RS11525	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_RS11530	COG1309	transcriptional regulator
CTZ19_RS11535	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS11540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ19_RS11545	COG1024	Enoyl-CoA hydratase
CTZ19_RS11550	COG4770	biotin carboxylase activity
CTZ19_RS11560	COG0583	DNA-binding transcription factor activity
CTZ19_RS11575	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS11585	COG2814	Major facilitator Superfamily
CTZ19_RS11595	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ19_RS11600	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ19_RS11605	COG2814	Major facilitator Superfamily
CTZ19_RS11610	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS11615	COG1024	Enoyl-CoA hydratase
CTZ19_RS11620	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS11625	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ19_RS11630	COG0183	Belongs to the thiolase family
CTZ19_RS11640	COG2814	Major facilitator Superfamily
CTZ19_RS11650	COG1024	Enoyl-CoA hydratase
CTZ19_RS11665	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS11670	COG2814	Major facilitator Superfamily
CTZ19_RS11675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ19_RS11680	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTZ19_RS11695	COG3842	ATPase activity
CTZ19_RS11700	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ19_RS11710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_RS11715	COG1414	Transcriptional regulator
CTZ19_RS11725	COG0583	DNA-binding transcription factor activity
CTZ19_RS11730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ19_RS11735	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS11745	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ19_RS11755	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS11760	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_RS11765	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_RS11770	COG2267	carboxylic ester hydrolase activity
CTZ19_RS11790	COG3038	cytochrome b561
CTZ19_RS11795	COG0753	catalase activity
CTZ19_RS11835	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ19_RS11845	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ19_RS11850	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ19_RS11855	COG0183	Belongs to the thiolase family
CTZ19_RS11860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ19_RS11865	COG1024	Enoyl-CoA hydratase
CTZ19_RS11870	COG1024	Enoyl-CoA hydratase
CTZ19_RS11875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ19_RS11880	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ19_RS11885	COG3396	Phenylacetate-CoA oxygenase
CTZ19_RS11890	COG3460	Phenylacetate-CoA oxygenase
CTZ19_RS11895	COG3396	Phenylacetate-CoA oxygenase
CTZ19_RS11900	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS11900	COG2030	dehydratase
CTZ19_RS11905	COG1760	l-serine dehydratase
CTZ19_RS11910	COG0531	amino acid
CTZ19_RS11915	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS11930	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_RS11940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ19_RS11960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_RS11975	COG0789	Transcriptional regulator
CTZ19_RS12000	COG1116	anion transmembrane transporter activity
CTZ19_RS12005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ19_RS12015	COG0864	Transcriptional regulator
CTZ19_RS12035	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ19_RS12040	COG0439	Biotin carboxylase
CTZ19_RS12055	COG1063	alcohol dehydrogenase
CTZ19_RS12065	COG1309	transcriptional regulator
CTZ19_RS12090	COG0038	chloride channel
CTZ19_RS12095	COG4770	biotin carboxylase activity
CTZ19_RS12115	COG1914	H( )-stimulated, divalent metal cation uptake system
CTZ19_RS12120	COG0583	DNA-binding transcription factor activity
CTZ19_RS12175	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ19_RS12195	COG2814	Major facilitator Superfamily
CTZ19_RS12205	COG1560	Kdo2-lipid A biosynthetic process
CTZ19_RS12215	COG5006	permease, DMT superfamily
CTZ19_RS12220	COG1522	sequence-specific DNA binding
CTZ19_RS12235	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ19_RS12245	COG4122	O-methyltransferase activity
CTZ19_RS12275	COG1538	Outer membrane efflux protein
CTZ19_RS12280	COG1137	ATPase activity
CTZ19_RS12285	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ19_RS12295	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ19_RS12300	COG0517	IMP dehydrogenase activity
CTZ19_RS12300	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ19_RS12340	COG2814	Major facilitator Superfamily
CTZ19_RS12380	COG1278	Cold shock
CTZ19_RS12385	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS12420	COG1570	exodeoxyribonuclease VII activity
CTZ19_RS12475	COG0583	DNA-binding transcription factor activity
CTZ19_RS12480	COG4638	Rieske (2fe-2S)
CTZ19_RS12485	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ19_RS12490	COG0543	2 iron, 2 sulfur cluster binding
CTZ19_RS12490	COG0633	Ferredoxin
CTZ19_RS12495	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS12500	COG3135	benzoate transporter
CTZ19_RS12505	COG2814	Major facilitator Superfamily
CTZ19_RS12520	COG1643	Atp-dependent helicase
CTZ19_RS12525	COG0450	alkyl hydroperoxide reductase
CTZ19_RS12535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ19_RS12545	COG3634	alkyl hydroperoxide reductase activity
CTZ19_RS12565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ19_RS12570	COG0625	glutathione transferase activity
CTZ19_RS12580	COG2885	chlorophyll binding
CTZ19_RS12615	COG0542	response to heat
CTZ19_RS12630	COG1765	OsmC-like protein
CTZ19_RS12645	COG0667	Aldo Keto reductase
CTZ19_RS12660	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ19_RS12670	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ19_RS12680	COG0527	aspartate kinase activity
CTZ19_RS12690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ19_RS12700	COG3038	cytochrome b561
CTZ19_RS12705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ19_RS12795	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ19_RS12835	COG1113	amino acid transport
CTZ19_RS12855	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS12875	COG0531	amino acid
CTZ19_RS12885	COG1113	amino acid transport
CTZ19_RS12930	COG3209	COG3209 Rhs family protein
CTZ19_RS12955	COG4269	membrane
CTZ19_RS12970	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_RS12970	COG1902	pentaerythritol trinitrate reductase activity
CTZ19_RS12980	COG3706	GGDEF domain
CTZ19_RS12980	COG2203	Gaf domain
CTZ19_RS12980	COG5001	Diguanylate cyclase
CTZ19_RS12980	COG4251	negative regulation of phosphorylation
CTZ19_RS12990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_RS13010	COG4172	Belongs to the ABC transporter superfamily
CTZ19_RS13015	COG4239	(ABC) transporter, permease
CTZ19_RS13020	COG4174	ABC transporter (Permease)
CTZ19_RS13030	COG1388	LysM domain
CTZ19_RS13030	COG0741	lytic transglycosylase activity
CTZ19_RS13030	COG0741	lytic transglycosylase activity
CTZ19_RS13030	COG1388	LysM domain
CTZ19_RS13035	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_RS13075	COG0583	DNA-binding transcription factor activity
CTZ19_RS13080	COG1279	arginine transmembrane transporter activity
CTZ19_RS13100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_RS13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_RS13110	COG0006	proline dipeptidase activity
CTZ19_RS13145	COG2194	sulfuric ester hydrolase activity
CTZ19_RS13190	COG0739	heme binding
CTZ19_RS13555	COG0739	heme binding
CTZ19_RS13555	COG0741	lytic transglycosylase activity
CTZ19_RS13555	COG1196	nuclear chromosome segregation
CTZ19_RS13610	COG4695	Portal protein
CTZ19_RS13705	COG0305	Participates in initiation and elongation during chromosome replication
CTZ19_RS13725	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ19_RS13785	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ19_RS13810	COG3384	dioxygenase
CTZ19_RS13820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ19_RS13825	COG2878	Part of a membrane complex involved in electron transport
CTZ19_RS13830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ19_RS13855	COG0768	penicillin binding
CTZ19_RS13860	COG0742	ribosomal rna small subunit methyltransferase
CTZ19_RS13875	COG0830	nickel cation binding
CTZ19_RS13885	COG0804	urea catabolic process
CTZ19_RS13925	COG1253	flavin adenine dinucleotide binding
CTZ19_RS13935	COG2851	Citrate transporter
CTZ19_RS13985	COG1773	rubredoxin
CTZ19_RS13990	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ19_RS14000	COG0583	DNA-binding transcription factor activity
CTZ19_RS14030	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ19_RS14035	COG4181	ATPase activity
CTZ19_RS14080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ19_RS14100	COG0306	phosphate transporter
CTZ19_RS14110	COG3958	Transketolase
CTZ19_RS14115	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ19_RS14120	COG2271	Major facilitator Superfamily
CTZ19_RS14125	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS14130	COG0583	DNA-binding transcription factor activity
CTZ19_RS14150	COG2223	nitrite transmembrane transporter activity
CTZ19_RS14155	COG2207	Transcriptional regulator
CTZ19_RS14160	COG2066	Belongs to the glutaminase family
CTZ19_RS14165	COG0242	peptide deformylase activity
CTZ19_RS14170	COG0477	Major facilitator Superfamily
CTZ19_RS14180	COG0028	Belongs to the TPP enzyme family
CTZ19_RS14195	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS14200	COG2267	carboxylic ester hydrolase activity
CTZ19_RS14210	COG2271	Major facilitator Superfamily
CTZ19_RS14215	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ19_RS14225	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS14245	COG1414	Transcriptional regulator
CTZ19_RS14260	COG1024	Enoyl-CoA hydratase
CTZ19_RS14270	COG1215	transferase activity, transferring glycosyl groups
CTZ19_RS14275	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ19_RS14275	COG0726	polysaccharide deacetylase
CTZ19_RS14285	COG4681	YaeQ
CTZ19_RS14295	COG0523	cobalamin synthesis protein
CTZ19_RS14305	COG1607	acyl-coa hydrolase
CTZ19_RS14315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_RS14320	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ19_RS14325	COG1309	transcriptional regulator
CTZ19_RS14350	COG2040	homocysteine
CTZ19_RS14355	COG0531	amino acid
CTZ19_RS14410	COG1595	DNA-templated transcription, initiation
CTZ19_RS14420	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_RS14425	COG0477	Major facilitator Superfamily
CTZ19_RS14560	COG0592	DNA-directed DNA polymerase activity
CTZ19_RS14600	COG2026	Addiction module toxin, RelE StbE family
CTZ19_RS14750	COG3755	Protein conserved in bacteria
CTZ19_RS14795	COG1484	DNA-dependent DNA replication
CTZ19_RS14905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ19_RS14935	COG0405	Gamma-glutamyltransferase
CTZ19_RS14940	COG2814	Major facilitator Superfamily
CTZ19_RS14950	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ19_RS14965	COG1090	epimerase
CTZ19_RS14985	COG0420	3'-5' exonuclease activity
CTZ19_RS15015	COG0735	belongs to the Fur family
CTZ19_RS15020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ19_RS15055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ19_RS15065	COG0210	DNA helicase
CTZ19_RS15070	COG2885	chlorophyll binding
CTZ19_RS15075	COG0204	Acyl-transferase
CTZ19_RS15090	COG2894	cell division
CTZ19_RS15115	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS15120	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ19_RS15120	COG1674	ftsk spoiiie
CTZ19_RS15125	COG0492	ferredoxin-NADP+ reductase activity
CTZ19_RS15130	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ19_RS15140	COG0456	acetyltransferase
CTZ19_RS15185	COG1981	membrane
CTZ19_RS15200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ19_RS15200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ19_RS15220	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS15230	COG0657	acetylesterase activity
CTZ19_RS15240	COG0473	3-isopropylmalate dehydrogenase activity
CTZ19_RS15245	COG0583	DNA-binding transcription factor activity
CTZ19_RS15265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ19_RS15290	COG0564	pseudouridine synthase activity
CTZ19_RS15300	COG0358	DNA primase activity
CTZ19_RS15315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ19_RS15345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ19_RS15375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ19_RS15385	COG0352	thiamine-phosphate diphosphorylase activity
CTZ19_RS15385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ19_RS15385	COG0351	phosphomethylpyrimidine kinase
CTZ19_RS15390	COG1652	LysM domain
CTZ19_RS15415	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ19_RS15420	COG3101	peptidyl-lysine hydroxylation
CTZ19_RS15425	COG0009	L-threonylcarbamoyladenylate synthase
CTZ19_RS15430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ19_RS15435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ19_RS15450	COG4106	trans-aconitate 2-methyltransferase activity
CTZ19_RS15465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_RS15465	COG0596	Alpha beta hydrolase
CTZ19_RS15465	COG2226	methyltransferase
CTZ19_RS15470	COG1877	trehalose-phosphatase activity
CTZ19_RS15475	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ19_RS15480	COG2223	nitrite transmembrane transporter activity
CTZ19_RS15500	COG1196	nuclear chromosome segregation
CTZ19_RS15510	COG0730	response to heat
CTZ19_RS15525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ19_RS15535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ19_RS15595	COG0489	protein tyrosine kinase activity
CTZ19_RS15605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_RS15605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_RS15635	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ19_RS15640	COG2081	HI0933 family
CTZ19_RS15650	COG0668	transmembrane transport
CTZ19_RS15670	COG0583	DNA-binding transcription factor activity
CTZ19_RS15690	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ19_RS15695	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ19_RS15725	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ19_RS15765	COG0745	RESPONSE REGULATOR receiver
CTZ19_RS15785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ19_RS15795	COG2205	protein histidine kinase activity
CTZ19_RS15865	COG4993	Dehydrogenase
CTZ19_RS15885	COG0384	phenazine biosynthesis protein PhzF
CTZ19_RS15915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ19_RS15930	COG0583	DNA-binding transcription factor activity
CTZ19_RS15960	COG0583	DNA-binding transcription factor activity
CTZ19_RS15980	COG0583	DNA-binding transcription factor activity
CTZ19_RS15985	COG1053	succinate dehydrogenase
CTZ19_RS15995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ19_RS16000	COG2814	Major facilitator Superfamily
CTZ19_RS16005	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS16010	COG0583	DNA-binding transcription factor activity
CTZ19_RS16015	COG1063	alcohol dehydrogenase
CTZ19_RS16045	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ19_RS16050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ19_RS16055	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ19_RS16070	COG3667	copper resistance
CTZ19_RS16075	COG2132	Multicopper oxidase
CTZ19_RS16085	COG0561	phosphatase activity
CTZ19_RS16090	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ19_RS16115	COG1214	PFAM Peptidase M22, glycoprotease
CTZ19_RS16165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTZ19_RS16175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ19_RS16180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ19_RS16185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ19_RS16245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ19_RS16255	COG1846	Transcriptional regulator
CTZ19_RS16260	COG1764	response to oxidative stress
CTZ19_RS16300	COG0037	tRNA processing
CTZ19_RS16310	COG0248	Ppx GppA phosphatase
CTZ19_RS16340	COG0072	phenylalanine-tRNA ligase activity
CTZ19_RS16380	COG1238	metal cluster binding
CTZ19_RS16385	COG0625	glutathione transferase activity
CTZ19_RS16405	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_RS16410	COG3028	Belongs to the UPF0307 family
CTZ19_RS16415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ19_RS16435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ19_RS16440	COG0617	tRNA 3'-terminal CCA addition
CTZ19_RS16445	COG1555	photosystem II stabilization
CTZ19_RS16450	COG3956	TIGRFAM MazG family protein
CTZ19_RS16460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ19_RS16480	COG2205	protein histidine kinase activity
CTZ19_RS16480	COG0784	Response regulator, receiver
CTZ19_RS16480	COG5002	protein histidine kinase activity
CTZ19_RS16485	COG1024	Enoyl-CoA hydratase
CTZ19_RS16490	COG2084	Dehydrogenase
CTZ19_RS16495	COG3622	Belongs to the hyi family
CTZ19_RS16525	COG0697	spore germination
CTZ19_RS16535	COG2814	Major facilitator Superfamily
CTZ19_RS16540	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ19_RS16550	COG0583	DNA-binding transcription factor activity
CTZ19_RS16560	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ19_RS16575	COG0084	hydrolase, TatD family'
CTZ19_RS16590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ19_RS16625	COG0440	acetolactate synthase activity
CTZ19_RS16630	COG0028	Belongs to the TPP enzyme family
CTZ19_RS16655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ19_RS16660	COG0577	efflux transmembrane transporter activity
CTZ19_RS16660	COG1136	(ABC) transporter
CTZ19_RS16665	COG1538	Outer membrane efflux protein
CTZ19_RS16680	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ19_RS16685	COG1162	GTPase activity
CTZ19_RS16695	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ19_RS16715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ19_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS16760	COG2986	histidine ammonia-lyase
CTZ19_RS16775	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_RS16785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ19_RS16830	COG1426	Protein conserved in bacteria
CTZ19_RS16865	COG0793	Belongs to the peptidase S41A family
CTZ19_RS16880	COG2267	carboxylic ester hydrolase activity
CTZ19_RS16890	COG1012	belongs to the aldehyde dehydrogenase family
CTZ19_RS16895	COG3265	gluconokinase activity
CTZ19_RS16905	COG0800	Aldolase
CTZ19_RS16920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ19_RS16925	COG0857	belongs to the CobB CobQ family
CTZ19_RS16925	COG0280	phosphate acetyltransferase
CTZ19_RS16930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ19_RS16930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ19_RS16950	COG0740	serine-type endopeptidase activity
CTZ19_RS16960	COG4774	siderophore transport
CTZ19_RS16970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ19_RS16980	COG2813	Specifically methylates the guanine in position
CTZ19_RS16980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ19_RS17080	COG0788	formyltetrahydrofolate deformylase activity
CTZ19_RS17105	COG4651	solute:proton antiporter activity
CTZ19_RS17105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_RS17125	COG0724	RNA recognition motif
CTZ19_RS17130	COG0210	DNA helicase
CTZ19_RS17155	COG1733	regulation of RNA biosynthetic process
CTZ19_RS17165	COG2900	Belongs to the SlyX family
CTZ19_RS17170	COG0488	(ABC) transporter
CTZ19_RS17175	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS17180	COG1560	Kdo2-lipid A biosynthetic process
CTZ19_RS17190	COG1301	dicarboxylic acid transport
CTZ19_RS17245	COG0473	3-isopropylmalate dehydrogenase activity
CTZ19_RS17310	COG0583	DNA-binding transcription factor activity
CTZ19_RS17320	COG0625	glutathione transferase activity
CTZ19_RS17325	COG2378	regulation of single-species biofilm formation
CTZ19_RS17330	COG0546	phosphoglycolate phosphatase activity
CTZ19_RS17345	COG1530	ribonuclease E activity
CTZ19_RS17350	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_RS17365	COG0583	DNA-binding transcription factor activity
CTZ19_RS17370	COG4221	oxidoreductase activity
CTZ19_RS17375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ19_RS17385	COG0534	Mate efflux family protein
CTZ19_RS17400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ19_RS17440	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ19_RS17445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ19_RS17460	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ19_RS17470	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ19_RS17470	COG0644	oxidoreductase
CTZ19_RS17475	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ19_RS17480	COG4535	Mg2 and Co2 transporter CorC
CTZ19_RS17490	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ19_RS17510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ19_RS17515	COG0475	glutathione-regulated potassium exporter activity
CTZ19_RS17515	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ19_RS17520	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ19_RS17530	COG0484	heat shock protein binding
CTZ19_RS17535	COG0789	Transcriptional regulator
CTZ19_RS17540	COG0598	Magnesium transport protein CorA
CTZ19_RS17555	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ19_RS17560	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ19_RS17565	COG1074	ATP-dependent DNA helicase activity
CTZ19_RS17570	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ19_RS17590	COG2226	methyltransferase
CTZ19_RS17605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ19_RS17610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ19_RS17625	COG2111	Na H antiporter
CTZ19_RS17625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ19_RS17630	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ19_RS17635	COG0651	ATP synthesis coupled electron transport
CTZ19_RS17640	COG1863	multisubunit Na H antiporter MnhE subunit
CTZ19_RS17645	COG2212	antiporter activity
CTZ19_RS17650	COG1320	monovalent cation:proton antiporter activity
CTZ19_RS17665	COG0195	Participates in both transcription termination and antitermination
CTZ19_RS17715	COG0237	dephospho-CoA kinase activity
CTZ19_RS17725	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ19_RS17740	COG0497	DNA recombination
CTZ19_RS17750	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ19_RS17780	COG2169	Transcriptional regulator
CTZ19_RS17780	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ19_RS17785	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ19_RS17860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ19_RS17875	COG0326	Molecular chaperone. Has ATPase activity
CTZ19_RS17890	COG2056	Na+-H+ antiporter family
CTZ19_RS17895	COG0596	Alpha beta hydrolase
CTZ19_RS17990	COG0546	phosphoglycolate phosphatase activity
CTZ19_RS17995	COG1716	ATPase activity
CTZ19_RS18040	COG0181	hydroxymethylbilane synthase activity
CTZ19_RS18050	COG3275	phosphorelay sensor kinase activity
CTZ19_RS18070	COG1538	Outer membrane efflux protein
CTZ19_RS18080	COG0697	spore germination
CTZ19_RS18105	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ19_RS18110	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ19_RS18115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ19_RS18120	COG0772	Belongs to the SEDS family
CTZ19_RS18145	COG4974	Belongs to the 'phage' integrase family
CTZ19_RS18150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_RS18160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ19_RS18170	COG2197	response regulator
CTZ19_RS18185	COG0793	Belongs to the peptidase S41A family
CTZ19_RS18190	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ19_RS18195	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ19_RS18235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ19_RS18235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ19_RS18245	COG0004	ammonium transporteR
CTZ19_RS18250	COG0347	Belongs to the P(II) protein family
CTZ19_RS18260	COG0606	chelatase, subunit chli
CTZ19_RS18270	COG0659	secondary active sulfate transmembrane transporter activity
CTZ19_RS18275	COG0589	response to stress
CTZ19_RS18305	COG0606	chelatase, subunit chli
CTZ19_RS18310	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ19_RS18320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ19_RS18335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ19_RS18350	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ19_RS18360	COG0477	Major facilitator Superfamily
CTZ19_RS18365	COG2860	membrane
CTZ19_RS18375	COG1253	flavin adenine dinucleotide binding
CTZ19_RS18395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ19_RS18430	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTZ19_RS18440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ19_RS18475	COG1309	transcriptional regulator
CTZ19_RS18510	COG0758	DNA mediated transformation
CTZ19_RS18520	COG0697	spore germination
CTZ19_RS18525	COG1309	transcriptional regulator
CTZ19_RS18540	COG0386	Belongs to the glutathione peroxidase family
CTZ19_RS18605	COG1121	(ABC) transporter
CTZ19_RS18610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ19_RS18615	COG1280	lysine exporter protein (LysE YggA)
CTZ19_RS18620	COG2837	iron assimilation
CTZ19_RS18625	COG0281	malic enzyme
CTZ19_RS18670	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ19_RS18670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ19_RS18675	COG4399	Belongs to the UPF0754 family
CTZ19_RS18680	COG2259	Doxx family
CTZ19_RS18685	COG0586	Pfam SNARE associated Golgi protein
CTZ19_RS18700	COG1192	Involved in chromosome partitioning
CTZ19_RS18710	COG0271	Belongs to the BolA IbaG family
CTZ19_RS18750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ19_RS18750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ19_RS18750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTZ19_RS18750	COG3321	synthase
CTZ19_RS18755	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS18770	COG2197	response regulator
CTZ19_RS18780	COG3916	Acyl-homoserine-lactone synthase
CTZ19_RS18785	COG0477	Major facilitator Superfamily
CTZ19_RS18790	COG1024	Enoyl-CoA hydratase
CTZ19_RS18795	COG1024	Enoyl-CoA hydratase
CTZ19_RS18800	COG1960	acyl-CoA dehydrogenase activity
CTZ19_RS18805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ19_RS18830	COG1113	amino acid transport
CTZ19_RS18835	COG1113	amino acid transport
CTZ19_RS18840	COG0251	oxidation-reduction process
CTZ19_RS18880	COG0564	pseudouridine synthase activity
CTZ19_RS18950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTZ19_RS18965	COG1802	Transcriptional regulator
CTZ19_RS18975	COG1448	Aminotransferase
CTZ19_RS18980	COG0277	FAD linked oxidase domain protein
CTZ19_RS18990	COG2186	Transcriptional regulator
CTZ19_RS19000	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ19_RS19005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ19_RS19020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ19_RS19025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ19_RS19030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTZ19_RS19090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ19_RS19095	COG1596	polysaccharide export
CTZ19_RS19120	COG0728	peptidoglycan biosynthetic process
CTZ19_RS19125	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ19_RS19185	COG0546	phosphoglycolate phosphatase activity
CTZ19_RS19190	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ19_RS19210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_RS19215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ19_RS19220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ19_RS19225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ19_RS19230	COG1116	anion transmembrane transporter activity
CTZ19_RS19235	COG1309	transcriptional regulator
CTZ19_RS19240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTZ19_RS19250	COG0196	riboflavin kinase activity
CTZ19_RS19255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ19_RS19265	COG1047	Peptidyl-prolyl cis-trans
CTZ19_RS19305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ19_RS19310	COG0657	acetylesterase activity
CTZ19_RS19360	COG2951	lytic endotransglycosylase activity
CTZ19_RS19365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ19_RS19385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ19_RS19395	COG0671	phosphoesterase, PA-phosphatase related
CTZ19_RS19400	COG0861	Integral membrane protein TerC family
CTZ19_RS19410	COG0754	glutathionylspermidine amidase activity
CTZ19_RS19420	COG0402	S-adenosylhomocysteine deaminase activity
CTZ19_RS19435	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ19_RS19440	COG1230	cation diffusion facilitator family transporter
CTZ19_RS19455	COG0706	membrane insertase activity