locus-tag	class	description
CTZ20_RS00010	COG0592	DNA-directed DNA polymerase activity
CTZ20_RS00020	COG0187	DNA topoisomerase II activity
CTZ20_RS00030	COG0586	Pfam SNARE associated Golgi protein
CTZ20_RS00035	COG0488	(ABC) transporter
CTZ20_RS00060	COG0596	Alpha beta hydrolase
CTZ20_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CTZ20_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CTZ20_RS00165	COG2233	PERMEase
CTZ20_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS00215	COG2814	Major facilitator Superfamily
CTZ20_RS00220	COG0656	L-ascorbic acid biosynthetic process
CTZ20_RS00225	COG0583	DNA-binding transcription factor activity
CTZ20_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_RS00245	COG1064	alcohol dehydrogenase
CTZ20_RS00250	COG2818	Glycosylase
CTZ20_RS00265	COG1194	a g-specific adenine glycosylase
CTZ20_RS00285	COG2983	Belongs to the UPF0260 family
CTZ20_RS00290	COG2133	pyrroloquinoline quinone binding
CTZ20_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CTZ20_RS00300	COG2116	formate transmembrane transporter activity
CTZ20_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_RS00325	COG1335	isochorismatase
CTZ20_RS00330	COG0385	Bile acid
CTZ20_RS00335	COG0534	Mate efflux family protein
CTZ20_RS00340	COG1683	Conserved Protein
CTZ20_RS00360	COG0625	glutathione transferase activity
CTZ20_RS00370	COG1113	amino acid transport
CTZ20_RS00380	COG0523	cobalamin synthesis protein
CTZ20_RS00390	COG2188	Transcriptional regulator
CTZ20_RS00420	COG0010	Belongs to the arginase family
CTZ20_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ20_RS00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CTZ20_RS00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CTZ20_RS00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CTZ20_RS00560	COG0534	Mate efflux family protein
CTZ20_RS00565	COG0436	Aminotransferase
CTZ20_RS00570	COG2733	membrane
CTZ20_RS00585	COG2918	glutathione biosynthetic process
CTZ20_RS00600	COG0791	NLP P60 protein
CTZ20_RS00600	COG1388	LysM domain
CTZ20_RS00615	COG3150	esterase
CTZ20_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CTZ20_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_RS00650	COG2233	PERMEase
CTZ20_RS00655	COG2351	hydroxyisourate hydrolase activity
CTZ20_RS00690	COG3706	GGDEF domain
CTZ20_RS00705	COG1393	Belongs to the ArsC family
CTZ20_RS00710	COG0708	Exodeoxyribonuclease III
CTZ20_RS00730	COG0189	ligase activity
CTZ20_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CTZ20_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CTZ20_RS00775	COG4942	peptidase
CTZ20_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ20_RS00795	COG2119	membrane
CTZ20_RS00800	COG4774	siderophore transport
CTZ20_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_RS00805	COG0426	domain, Protein
CTZ20_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CTZ20_RS00850	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_RS00855	COG1519	Transferase
CTZ20_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ20_RS00865	COG0668	transmembrane transport
CTZ20_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_RS00885	COG1335	isochorismatase
CTZ20_RS00890	COG1522	sequence-specific DNA binding
CTZ20_RS00895	COG3328	transposase activity
CTZ20_RS00920	COG0784	Response regulator, receiver
CTZ20_RS00920	COG2205	protein histidine kinase activity
CTZ20_RS00920	COG2198	Histidine kinase
CTZ20_RS00925	COG3162	membrane
CTZ20_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ20_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_RS00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CTZ20_RS00965	COG1309	transcriptional regulator
CTZ20_RS00985	COG0351	phosphomethylpyrimidine kinase
CTZ20_RS00985	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_RS00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ20_RS00995	COG2814	Major facilitator Superfamily
CTZ20_RS01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ20_RS01020	COG1113	amino acid transport
CTZ20_RS01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ20_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS01045	COG1335	isochorismatase
CTZ20_RS01075	COG2814	Major facilitator Superfamily
CTZ20_RS01080	COG0583	DNA-binding transcription factor activity
CTZ20_RS01100	COG0667	Aldo Keto reductase
CTZ20_RS01135	COG1733	regulation of RNA biosynthetic process
CTZ20_RS01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_RS01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CTZ20_RS01225	COG2329	Antibiotic biosynthesis monooxygenase
CTZ20_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CTZ20_RS01285	COG0427	acetyl-CoA hydrolase
CTZ20_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_RS01315	COG4221	oxidoreductase activity
CTZ20_RS01320	COG2873	o-acetylhomoserine
CTZ20_RS01325	COG0488	(ABC) transporter
CTZ20_RS01410	COG0833	amino acid
CTZ20_RS01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CTZ20_RS01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CTZ20_RS01475	COG2226	methyltransferase
CTZ20_RS01525	COG0070	glutamate synthase
CTZ20_RS01525	COG0069	glutamate synthase activity
CTZ20_RS01525	COG0067	glutamate synthase
CTZ20_RS01530	COG0493	'glutamate synthase
CTZ20_RS01540	COG1704	LemA family
CTZ20_RS01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CTZ20_RS01565	COG3307	-O-antigen
CTZ20_RS01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ20_RS01595	COG0194	GDP metabolic process
CTZ20_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CTZ20_RS01665	COG5380	lipid catabolic process
CTZ20_RS01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CTZ20_RS01695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CTZ20_RS01700	COG0277	FAD linked oxidase domain protein
CTZ20_RS01710	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CTZ20_RS01715	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_RS01730	COG1289	transmembrane transporter activity
CTZ20_RS01740	COG0628	permease
CTZ20_RS01745	COG1192	Involved in chromosome partitioning
CTZ20_RS01775	COG0833	amino acid
CTZ20_RS01780	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ20_RS01785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ20_RS01795	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS01835	COG0583	DNA-binding transcription factor activity
CTZ20_RS01880	COG0517	IMP dehydrogenase activity
CTZ20_RS01885	COG1983	PspC domain protein
CTZ20_RS01895	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS01910	COG0408	coproporphyrinogen oxidase activity
CTZ20_RS01930	COG0513	Belongs to the DEAD box helicase family
CTZ20_RS01935	COG1127	ABC transporter
CTZ20_RS01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CTZ20_RS01950	COG2854	intermembrane phospholipid transfer
CTZ20_RS01960	COG0598	Magnesium transport protein CorA
CTZ20_RS01970	COG0494	nUDIX hydrolase
CTZ20_RS01975	COG1040	competence protein
CTZ20_RS01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CTZ20_RS02000	COG1946	Acyl-CoA thioesterase
CTZ20_RS02005	COG1301	dicarboxylic acid transport
CTZ20_RS02020	COG1959	2 iron, 2 sulfur cluster binding
CTZ20_RS02025	COG1017	nitric oxide dioxygenase activity
CTZ20_RS02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_RS02030	COG0433	COG0433 Predicted ATPase
CTZ20_RS02035	COG0626	cystathionine gamma-synthase activity
CTZ20_RS02190	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CTZ20_RS02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CTZ20_RS02230	COG0339	signal peptide processing
CTZ20_RS02235	COG0557	exoribonuclease II activity
CTZ20_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
CTZ20_RS02285	COG2169	Transcriptional regulator
CTZ20_RS02290	COG0697	spore germination
CTZ20_RS02295	COG1295	ribonuclease BN
CTZ20_RS02330	COG1702	phosphate starvation-inducible protein PhoH
CTZ20_RS02340	COG1196	nuclear chromosome segregation
CTZ20_RS02340	COG0741	lytic transglycosylase activity
CTZ20_RS02340	COG0739	heme binding
CTZ20_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CTZ20_RS02375	COG1183	phosphatidylcholine synthase activity
CTZ20_RS02420	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS02425	COG1309	transcriptional regulator
CTZ20_RS02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ20_RS02445	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS02465	COG2969	positive regulation of protein catabolic process
CTZ20_RS02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CTZ20_RS02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CTZ20_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CTZ20_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CTZ20_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ20_RS02530	COG1408	metallophosphoesterase
CTZ20_RS02540	COG2199	diguanylate cyclase activity
CTZ20_RS02600	COG1607	acyl-coa hydrolase
CTZ20_RS02630	COG2350	Protein conserved in bacteria
CTZ20_RS02640	COG0613	PHP domain protein
CTZ20_RS02645	COG3781	membrane
CTZ20_RS02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CTZ20_RS02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CTZ20_RS02670	COG1862	Preprotein translocase
CTZ20_RS02700	COG2205	protein histidine kinase activity
CTZ20_RS02705	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CTZ20_RS02725	COG0726	polysaccharide deacetylase
CTZ20_RS02730	COG0463	Glycosyl transferase, family 2
CTZ20_RS02735	COG0438	transferase activity, transferring glycosyl groups
CTZ20_RS02800	COG0625	glutathione transferase activity
CTZ20_RS02805	COG0583	DNA-binding transcription factor activity
CTZ20_RS02810	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS02815	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS02825	COG2205	protein histidine kinase activity
CTZ20_RS02830	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CTZ20_RS02855	COG2096	Adenosyltransferase
CTZ20_RS02905	COG0285	dihydrofolate synthase activity
CTZ20_RS02925	COG0450	alkyl hydroperoxide reductase
CTZ20_RS02940	COG0477	Major facilitator Superfamily
CTZ20_RS02945	COG1272	protein, Hemolysin III
CTZ20_RS02975	COG0183	Belongs to the thiolase family
CTZ20_RS02980	COG2207	Transcriptional regulator
CTZ20_RS03000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_RS03020	COG0183	Belongs to the thiolase family
CTZ20_RS03030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CTZ20_RS03030	COG2885	chlorophyll binding
CTZ20_RS03040	COG1690	Belongs to the RtcB family
CTZ20_RS03045	COG0833	amino acid
CTZ20_RS03055	COG2233	PERMEase
CTZ20_RS03060	COG1217	gtp-binding protein TYPA
CTZ20_RS03085	COG2094	Belongs to the DNA glycosylase MPG family
CTZ20_RS03090	COG4772	TonB-dependent receptor
CTZ20_RS03105	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_RS03120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_RS03125	COG0354	folic acid binding
CTZ20_RS03135	COG3189	MarR family transcriptional regulator
CTZ20_RS03140	COG2824	Alkylphosphonate utilization operon protein PhnA
CTZ20_RS03145	COG3422	double-strand break repair
CTZ20_RS03185	COG0840	transmembrane signaling receptor activity
CTZ20_RS03205	COG5510	response to toxic substance
CTZ20_RS03215	COG2832	Protein of unknown function (DUF454)
CTZ20_RS03220	COG1376	ErfK ybiS ycfS ynhG family protein
CTZ20_RS03260	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CTZ20_RS03270	COG1289	transmembrane transporter activity
CTZ20_RS03275	COG2814	Major facilitator Superfamily
CTZ20_RS03295	COG1115	amino acid carrier protein
CTZ20_RS03300	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ20_RS03305	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ20_RS03310	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CTZ20_RS03340	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ20_RS03350	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CTZ20_RS03355	COG1077	Cell shape determining protein MreB Mrl
CTZ20_RS03360	COG1792	Involved in formation and maintenance of cell shape
CTZ20_RS03365	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CTZ20_RS03370	COG0424	maF-like protein
CTZ20_RS03375	COG1530	ribonuclease E activity
CTZ20_RS03385	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_RS03395	COG0560	Phosphoserine phosphatase
CTZ20_RS03405	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_RS03430	COG2207	Transcriptional regulator
CTZ20_RS03450	COG1113	amino acid transport
CTZ20_RS03455	COG2828	Protein conserved in bacteria
CTZ20_RS03460	COG0142	geranyltranstransferase activity
CTZ20_RS03465	COG2315	Protein conserved in bacteria
CTZ20_RS03480	COG1752	Esterase of the alpha-beta hydrolase superfamily
CTZ20_RS03500	COG2194	sulfuric ester hydrolase activity
CTZ20_RS03505	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS03510	COG0642	Histidine kinase
CTZ20_RS03520	COG0004	ammonium transporteR
CTZ20_RS03530	COG0583	DNA-binding transcription factor activity
CTZ20_RS03550	COG0525	valine-tRNA ligase activity
CTZ20_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS03570	COG0393	Putative heavy-metal-binding
CTZ20_RS03575	COG0393	Putative heavy-metal-binding
CTZ20_RS03580	COG1538	Outer membrane efflux protein
CTZ20_RS03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS03595	COG0671	phosphoesterase, PA-phosphatase related
CTZ20_RS03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CTZ20_RS03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CTZ20_RS03640	COG1648	precorrin-2 dehydrogenase activity
CTZ20_RS03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CTZ20_RS03650	COG1733	regulation of RNA biosynthetic process
CTZ20_RS03660	COG0531	amino acid
CTZ20_RS03675	COG0321	lipoyl(octanoyl) transferase activity
CTZ20_RS03680	COG2921	Belongs to the UPF0250 family
CTZ20_RS03720	COG2009	succinate dehydrogenase
CTZ20_RS03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CTZ20_RS03730	COG1053	succinate dehydrogenase
CTZ20_RS03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CTZ20_RS03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_RS03780	COG2354	Protein conserved in bacteria
CTZ20_RS03785	COG2321	neutral zinc metallopeptidase
CTZ20_RS03830	COG2843	Capsule synthesis protein
CTZ20_RS03845	COG0589	response to stress
CTZ20_RS03865	COG0505	Belongs to the CarA family
CTZ20_RS03890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ20_RS03895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CTZ20_RS03945	COG0477	Major facilitator Superfamily
CTZ20_RS03950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CTZ20_RS03965	COG1597	lipid kinase activity
CTZ20_RS03970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ20_RS04000	COG0584	glycerophosphoryl diester phosphodiesterase
CTZ20_RS04020	COG0741	lytic transglycosylase activity
CTZ20_RS04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CTZ20_RS04060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_RS04090	COG0778	Nitroreductase
CTZ20_RS04105	COG1929	Belongs to the glycerate kinase type-1 family
CTZ20_RS04110	COG0243	molybdopterin cofactor binding
CTZ20_RS04115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CTZ20_RS04120	COG3339	Conserved Protein
CTZ20_RS04130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CTZ20_RS04145	COG1113	amino acid transport
CTZ20_RS04155	COG0019	diaminopimelate decarboxylase activity
CTZ20_RS04165	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS04170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CTZ20_RS04200	COG0463	Glycosyl transferase, family 2
CTZ20_RS04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS04250	COG4591	ABC-type transport system involved in lipoprotein release permease component
CTZ20_RS04255	COG1136	(ABC) transporter
CTZ20_RS04260	COG2333	competence protein COMEC
CTZ20_RS04260	COG0658	competence protein
CTZ20_RS04270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CTZ20_RS04270	COG0616	signal peptide processing
CTZ20_RS04275	COG0596	Alpha beta hydrolase
CTZ20_RS04280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CTZ20_RS04290	COG0628	permease
CTZ20_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ20_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
CTZ20_RS04365	COG0824	Thioesterase
CTZ20_RS04370	COG1473	amidohydrolase
CTZ20_RS04390	COG0047	phosphoribosylformylglycinamidine synthase activity
CTZ20_RS04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CTZ20_RS04395	COG2814	Major facilitator Superfamily
CTZ20_RS04405	COG1024	Enoyl-CoA hydratase
CTZ20_RS04410	COG1051	belongs to the nudix hydrolase family
CTZ20_RS04410	COG1056	cytidyltransferase-related domain
CTZ20_RS04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CTZ20_RS04435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CTZ20_RS04450	COG4625	pathogenesis
CTZ20_RS04455	COG0583	DNA-binding transcription factor activity
CTZ20_RS04460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CTZ20_RS04465	COG4208	sulfate ABC transporter
CTZ20_RS04470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CTZ20_RS04480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CTZ20_RS04485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CTZ20_RS04490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CTZ20_RS04510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ20_RS04525	COG0681	Belongs to the peptidase S26 family
CTZ20_RS04540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CTZ20_RS04550	COG1381	Involved in DNA repair and RecF pathway recombination
CTZ20_RS04555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CTZ20_RS04565	COG4221	oxidoreductase activity
CTZ20_RS04595	COG0436	Aminotransferase
CTZ20_RS04615	COG0556	nucleotide-excision repair
CTZ20_RS04810	COG5410	chromosome segregation
CTZ20_RS05000	COG2070	2-Nitropropane dioxygenase
CTZ20_RS05030	COG1215	transferase activity, transferring glycosyl groups
CTZ20_RS05045	COG0415	Belongs to the DNA photolyase family
CTZ20_RS05055	COG1252	NADH dehydrogenase
CTZ20_RS05060	COG1686	Belongs to the peptidase S11 family
CTZ20_RS05075	COG1187	pseudouridine synthase activity
CTZ20_RS05100	COG0477	Major facilitator Superfamily
CTZ20_RS05105	COG0583	DNA-binding transcription factor activity
CTZ20_RS05110	COG1823	symporter activity
CTZ20_RS05120	COG0612	Peptidase, M16
CTZ20_RS05145	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_RS05180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_RS05195	COG1309	transcriptional regulator
CTZ20_RS05205	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CTZ20_RS05210	COG0076	glutamate decarboxylase activity
CTZ20_RS05220	COG1522	sequence-specific DNA binding
CTZ20_RS05225	COG3961	Belongs to the TPP enzyme family
CTZ20_RS05230	COG1113	amino acid transport
CTZ20_RS05235	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CTZ20_RS05240	COG0573	inorganic phosphate transmembrane transporter activity
CTZ20_RS05250	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CTZ20_RS05255	COG0616	signal peptide processing
CTZ20_RS05290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CTZ20_RS05295	COG1686	Belongs to the peptidase S11 family
CTZ20_RS05320	COG0583	DNA-binding transcription factor activity
CTZ20_RS05325	COG1067	ATP-dependent peptidase activity
CTZ20_RS05370	COG1966	Carbon starvation protein
CTZ20_RS05375	COG2879	small protein
CTZ20_RS05410	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CTZ20_RS05410	COG2508	Transcriptional regulator
CTZ20_RS05430	COG1113	amino acid transport
CTZ20_RS05435	COG0583	DNA-binding transcription factor activity
CTZ20_RS05440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_RS05445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_RS05455	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS05460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_RS05465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_RS05465	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CTZ20_RS05500	COG2814	Major facilitator Superfamily
CTZ20_RS05505	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ20_RS05515	COG1309	transcriptional regulator
CTZ20_RS05535	COG1741	Belongs to the pirin family
CTZ20_RS05545	COG2964	Protein conserved in bacteria
CTZ20_RS05560	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CTZ20_RS05565	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ20_RS05570	COG4605	iron ion homeostasis
CTZ20_RS05575	COG4604	ABC transporter, ATP-binding protein
CTZ20_RS05605	COG3433	isochorismatase activity
CTZ20_RS05605	COG1535	isochorismatase
CTZ20_RS05620	COG1132	(ABC) transporter
CTZ20_RS05625	COG1132	(ABC) transporter
CTZ20_RS05630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CTZ20_RS05640	COG1169	isochorismate synthase
CTZ20_RS05655	COG3739	integral membrane protein
CTZ20_RS05680	COG0302	gtp cyclohydrolase
CTZ20_RS05690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CTZ20_RS05720	COG0308	aminopeptidase N
CTZ20_RS05725	COG0512	Glutamine amidotransferase of anthranilate synthase
CTZ20_RS05740	COG0174	glutamine synthetase
CTZ20_RS05750	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CTZ20_RS05785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CTZ20_RS05790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CTZ20_RS05795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CTZ20_RS05815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CTZ20_RS05820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CTZ20_RS05825	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CTZ20_RS05840	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS05845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ20_RS05850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_RS05860	COG2223	nitrite transmembrane transporter activity
CTZ20_RS05870	COG0024	Methionine aminopeptidase
CTZ20_RS05875	COG0052	Belongs to the universal ribosomal protein uS2 family
CTZ20_RS05890	COG2207	Transcriptional regulator
CTZ20_RS05915	COG2951	lytic endotransglycosylase activity
CTZ20_RS05920	COG0772	Belongs to the SEDS family
CTZ20_RS05935	COG0842	Transport permease protein
CTZ20_RS05940	COG1131	(ABC) transporter
CTZ20_RS05985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS06000	COG4215	(ABC) transporter
CTZ20_RS06005	COG4160	amino acid transport
CTZ20_RS06010	COG4598	ABC transporter
CTZ20_RS06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ20_RS06025	COG0826	peptidase U32
CTZ20_RS06030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_RS06045	COG1720	tRNA m6t6A37 methyltransferase activity
CTZ20_RS06055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CTZ20_RS06070	COG0642	Histidine kinase
CTZ20_RS06080	COG0494	nUDIX hydrolase
CTZ20_RS06090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CTZ20_RS06095	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CTZ20_RS06100	COG3139	Protein of unknown function (DUF1315)
CTZ20_RS06105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CTZ20_RS06115	COG1301	dicarboxylic acid transport
CTZ20_RS06120	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS06125	COG2819	hydrolase of the alpha beta superfamily
CTZ20_RS06135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CTZ20_RS06145	COG2195	Cleaves the N-terminal amino acid of tripeptides
CTZ20_RS06150	COG1234	tRNA 3'-trailer cleavage
CTZ20_RS06180	COG2363	Small membrane protein
CTZ20_RS06200	COG0513	Belongs to the DEAD box helicase family
CTZ20_RS06210	COG0778	Nitroreductase
CTZ20_RS06240	COG1286	toxin biosynthetic process
CTZ20_RS06265	COG4783	chaperone-mediated protein folding
CTZ20_RS06270	COG1610	YqeY-like protein
CTZ20_RS06370	COG3111	PFAM Bacterial OB fold (BOF) protein
CTZ20_RS06395	COG3243	poly(R)-hydroxyalkanoic acid synthase
CTZ20_RS06400	COG0786	glutamate:sodium symporter activity
CTZ20_RS06410	COG2186	Transcriptional regulator
CTZ20_RS06460	COG0477	Major facilitator Superfamily
CTZ20_RS06490	COG2985	domain, Protein
CTZ20_RS06500	COG2995	paraquat-inducible protein a
CTZ20_RS06515	COG2011	ABC-type metal ion transport system permease component
CTZ20_RS06520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_RS06545	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ20_RS06550	COG1464	Belongs to the NlpA lipoprotein family
CTZ20_RS06555	COG0151	Belongs to the GarS family
CTZ20_RS06560	COG0138	bifunctional purine biosynthesis protein purh
CTZ20_RS06565	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CTZ20_RS06595	COG2308	Evidence 4 Homologs of previously reported genes of
CTZ20_RS06605	COG1305	Transglutaminase-like
CTZ20_RS06615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CTZ20_RS06620	COG0305	Participates in initiation and elongation during chromosome replication
CTZ20_RS06645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CTZ20_RS06655	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CTZ20_RS06660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CTZ20_RS06685	COG0726	polysaccharide deacetylase
CTZ20_RS06685	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ20_RS06690	COG1215	transferase activity, transferring glycosyl groups
CTZ20_RS06705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_RS06725	COG0583	DNA-binding transcription factor activity
CTZ20_RS06745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_RS06750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_RS06765	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS06770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_RS06775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_RS06800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CTZ20_RS06805	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CTZ20_RS06815	COG2205	protein histidine kinase activity
CTZ20_RS06820	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS06825	COG0174	glutamine synthetase
CTZ20_RS06845	COG0729	surface antigen
CTZ20_RS06875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ20_RS06880	COG2814	Major facilitator Superfamily
CTZ20_RS06895	COG0583	DNA-binding transcription factor activity
CTZ20_RS06910	COG1187	pseudouridine synthase activity
CTZ20_RS06930	COG0802	atpase or kinase
CTZ20_RS06935	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CTZ20_RS06945	COG1923	regulation of RNA biosynthetic process
CTZ20_RS06950	COG0697	spore germination
CTZ20_RS06965	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_RS06975	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ20_RS06980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ20_RS06980	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ20_RS06985	COG4302	ethanolamine ammonia-lyase activity
CTZ20_RS06990	COG4303	Ethanolamine ammonia lyase large subunit
CTZ20_RS06995	COG0531	amino acid
CTZ20_RS07015	COG1454	alcohol dehydrogenase
CTZ20_RS07020	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ20_RS07030	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CTZ20_RS07050	COG0308	aminopeptidase N
CTZ20_RS07060	COG4221	oxidoreductase activity
CTZ20_RS07070	COG1605	Chorismate mutase
CTZ20_RS07090	COG1309	transcriptional regulator
CTZ20_RS07100	COG0668	transmembrane transport
CTZ20_RS07135	COG4773	Receptor
CTZ20_RS07155	COG0488	(ABC) transporter
CTZ20_RS07160	COG0589	response to stress
CTZ20_RS07180	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CTZ20_RS07190	COG3135	benzoate transporter
CTZ20_RS07195	COG1522	sequence-specific DNA binding
CTZ20_RS07205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CTZ20_RS07210	COG0583	DNA-binding transcription factor activity
CTZ20_RS07220	COG0183	Belongs to the thiolase family
CTZ20_RS07230	COG2030	dehydratase
CTZ20_RS07235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ20_RS07250	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CTZ20_RS07260	COG0824	Thioesterase
CTZ20_RS07265	COG1454	alcohol dehydrogenase
CTZ20_RS07275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CTZ20_RS07295	COG0069	glutamate synthase activity
CTZ20_RS07455	COG5410	chromosome segregation
CTZ20_RS07580	COG0739	heme binding
CTZ20_RS07650	COG2814	Major facilitator Superfamily
CTZ20_RS07665	COG0511	ligase activity, forming carbon-carbon bonds
CTZ20_RS07685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_RS07685	COG1116	anion transmembrane transporter activity
CTZ20_RS07690	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS07700	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_RS07700	COG2146	nitrite reductase [NAD(P)H] activity
CTZ20_RS07705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_RS07710	COG0243	molybdopterin cofactor binding
CTZ20_RS07720	COG0243	molybdopterin cofactor binding
CTZ20_RS07725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CTZ20_RS07740	COG0315	cyclic pyranopterin monophosphate synthase activity
CTZ20_RS07740	COG0521	Mo-molybdopterin cofactor biosynthetic process
CTZ20_RS07745	COG0303	'Molybdopterin
CTZ20_RS07755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_RS07760	COG0697	spore germination
CTZ20_RS07780	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CTZ20_RS07785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ20_RS07845	COG2204	response regulator
CTZ20_RS07850	COG3852	Histidine kinase
CTZ20_RS07870	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CTZ20_RS07875	COG0575	Belongs to the CDS family
CTZ20_RS07910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_RS07925	COG2137	regulation of response to DNA damage stimulus
CTZ20_RS07935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CTZ20_RS07940	COG1011	Hydrolase
CTZ20_RS07965	COG1522	sequence-specific DNA binding
CTZ20_RS07975	COG1113	amino acid transport
CTZ20_RS07995	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_RS08000	COG2135	peptidase activity
CTZ20_RS08015	COG3300	MHYT domain
CTZ20_RS08015	COG5001	Diguanylate cyclase
CTZ20_RS08035	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ20_RS08035	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CTZ20_RS08035	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CTZ20_RS08040	COG1105	Belongs to the carbohydrate kinase PfkB family
CTZ20_RS08045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CTZ20_RS08045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ20_RS08075	COG0024	Methionine aminopeptidase
CTZ20_RS08080	COG0583	DNA-binding transcription factor activity
CTZ20_RS08090	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CTZ20_RS08095	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CTZ20_RS08100	COG0516	GMP reductase activity
CTZ20_RS08100	COG0517	IMP dehydrogenase activity
CTZ20_RS08125	COG0552	protein localization to endoplasmic reticulum
CTZ20_RS08135	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CTZ20_RS08150	COG4890	Cyd operon protein YbgT
CTZ20_RS08155	COG1294	oxidase, subunit
CTZ20_RS08175	COG1585	Membrane protein implicated in regulation of membrane protease activity
CTZ20_RS08185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CTZ20_RS08190	COG4774	siderophore transport
CTZ20_RS08205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CTZ20_RS08210	COG0569	domain protein
CTZ20_RS08215	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CTZ20_RS08245	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CTZ20_RS08250	COG0542	response to heat
CTZ20_RS08275	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_RS08275	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_RS08320	COG2323	membrane
CTZ20_RS08325	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CTZ20_RS08335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_RS08340	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_RS08345	COG0183	Belongs to the thiolase family
CTZ20_RS08350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CTZ20_RS08355	COG0596	Alpha beta hydrolase
CTZ20_RS08360	COG2271	Major facilitator Superfamily
CTZ20_RS08365	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ20_RS08370	COG3485	protocatechuate 3,4-dioxygenase
CTZ20_RS08375	COG3485	protocatechuate 3,4-dioxygenase
CTZ20_RS08380	COG0710	3-dehydroquinate dehydratase activity
CTZ20_RS08385	COG3420	alginic acid biosynthetic process
CTZ20_RS08390	COG3659	wide pore channel activity
CTZ20_RS08395	COG4993	Dehydrogenase
CTZ20_RS08405	COG2391	methyltransferase activity
CTZ20_RS08420	COG1414	Transcriptional regulator
CTZ20_RS08425	COG0583	DNA-binding transcription factor activity
CTZ20_RS08430	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS08455	COG2814	Major facilitator Superfamily
CTZ20_RS08465	COG0154	amidase activity
CTZ20_RS08485	COG4638	Rieske (2fe-2S)
CTZ20_RS08495	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS08505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_RS08515	COG3733	amine oxidase
CTZ20_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS08535	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_RS08540	COG0183	Belongs to the thiolase family
CTZ20_RS08545	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_RS08550	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_RS08560	COG4829	muconolactone delta-isomerase
CTZ20_RS08565	COG4948	Mandelate Racemase Muconate Lactonizing
CTZ20_RS08570	COG0583	DNA-binding transcription factor activity
CTZ20_RS08580	COG2186	Transcriptional regulator
CTZ20_RS08600	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS08620	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS08625	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS08630	COG3829	transcription factor binding
CTZ20_RS08640	COG3162	membrane
CTZ20_RS08655	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS08670	COG0753	catalase activity
CTZ20_RS08695	COG1846	Transcriptional regulator
CTZ20_RS08700	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_RS08700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_RS08710	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CTZ20_RS08740	COG1309	transcriptional regulator
CTZ20_RS08750	COG1335	isochorismatase
CTZ20_RS08755	COG0583	DNA-binding transcription factor activity
CTZ20_RS08765	COG0475	glutathione-regulated potassium exporter activity
CTZ20_RS08765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_RS08775	COG1473	amidohydrolase
CTZ20_RS08790	COG2831	hemolysin activation secretion protein
CTZ20_RS08795	COG3210	domain, Protein
CTZ20_RS08825	COG2188	Transcriptional regulator
CTZ20_RS08840	COG0583	DNA-binding transcription factor activity
CTZ20_RS08870	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ20_RS08890	COG1566	PFAM secretion protein HlyD family protein
CTZ20_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS08910	COG0129	dihydroxy-acid dehydratase activity
CTZ20_RS08920	COG0583	DNA-binding transcription factor activity
CTZ20_RS08925	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CTZ20_RS08935	COG2084	Dehydrogenase
CTZ20_RS08940	COG2207	Transcriptional regulator
CTZ20_RS08955	COG1064	alcohol dehydrogenase
CTZ20_RS08965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CTZ20_RS08970	COG1120	ATPase activity
CTZ20_RS08990	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ20_RS09110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CTZ20_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS09180	COG2207	Transcriptional regulator
CTZ20_RS09190	COG2205	protein histidine kinase activity
CTZ20_RS09195	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS09205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS09210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ20_RS09215	COG1538	Outer membrane efflux protein
CTZ20_RS09225	COG2072	flavoprotein involved in K transport
CTZ20_RS09245	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_RS09265	COG3539	Fimbrial protein
CTZ20_RS09295	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CTZ20_RS09305	COG0753	catalase activity
CTZ20_RS09320	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CTZ20_RS09385	COG3433	isochorismatase activity
CTZ20_RS09385	COG1535	isochorismatase
CTZ20_RS09390	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS09395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CTZ20_RS09400	COG4149	molybdate abc transporter
CTZ20_RS09405	COG0725	ABC transporter, periplasmic molybdate-binding protein
CTZ20_RS09415	COG4638	Rieske (2fe-2S)
CTZ20_RS09420	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ20_RS09425	COG0543	2 iron, 2 sulfur cluster binding
CTZ20_RS09425	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS09465	COG2207	Transcriptional regulator
CTZ20_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS09480	COG2610	gluconate transmembrane transporter activity
CTZ20_RS09490	COG0583	DNA-binding transcription factor activity
CTZ20_RS09500	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_RS09505	COG2031	fatty acid transporter
CTZ20_RS09510	COG0183	Belongs to the thiolase family
CTZ20_RS09515	COG0583	DNA-binding transcription factor activity
CTZ20_RS09520	COG0583	DNA-binding transcription factor activity
CTZ20_RS09535	COG1027	Aspartate ammonia-lyase
CTZ20_RS09545	COG0477	Major facilitator Superfamily
CTZ20_RS09565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_RS09570	COG4521	taurine ABC transporter
CTZ20_RS09585	COG2188	Transcriptional regulator
CTZ20_RS09595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CTZ20_RS09600	COG1733	regulation of RNA biosynthetic process
CTZ20_RS09605	COG3708	Transcriptional regulator
CTZ20_RS09605	COG2207	Transcriptional regulator
CTZ20_RS09620	COG0730	response to heat
CTZ20_RS09630	COG3453	Protein conserved in bacteria
CTZ20_RS09630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_RS09640	COG3781	membrane
CTZ20_RS09645	COG1063	alcohol dehydrogenase
CTZ20_RS09655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CTZ20_RS09660	COG0508	dehydrogenase complex catalyzes the overall conversion of
CTZ20_RS09665	COG0022	dehydrogenase e1 component
CTZ20_RS09670	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CTZ20_RS09675	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CTZ20_RS09690	COG3706	GGDEF domain
CTZ20_RS09705	COG0133	tryptophan synthase activity
CTZ20_RS09715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CTZ20_RS09750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CTZ20_RS09775	COG2226	methyltransferase
CTZ20_RS09830	COG0842	Transport permease protein
CTZ20_RS09835	COG0842	Transport permease protein
CTZ20_RS09840	COG1131	(ABC) transporter
CTZ20_RS09855	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CTZ20_RS09860	COG4773	Receptor
CTZ20_RS09880	COG0730	response to heat
CTZ20_RS09885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CTZ20_RS09905	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CTZ20_RS09965	COG4264	IucA IucC family
CTZ20_RS09970	COG4264	IucA IucC family
CTZ20_RS09990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CTZ20_RS10005	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS10010	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS10015	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CTZ20_RS10020	COG2207	Transcriptional regulator
CTZ20_RS10025	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ20_RS10030	COG0776	regulation of translation
CTZ20_RS10055	COG0822	iron-sulfur transferase activity
CTZ20_RS10060	COG0316	Belongs to the HesB IscA family
CTZ20_RS10090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CTZ20_RS10110	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CTZ20_RS10115	COG0702	epimerase
CTZ20_RS10150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CTZ20_RS10160	COG0339	signal peptide processing
CTZ20_RS10205	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CTZ20_RS10210	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CTZ20_RS10240	COG0776	regulation of translation
CTZ20_RS10305	COG0084	hydrolase, TatD family'
CTZ20_RS10325	COG1663	tetraacyldisaccharide 4'-kinase activity
CTZ20_RS10330	COG1132	(ABC) transporter
CTZ20_RS10340	COG0811	peptide transport
CTZ20_RS10345	COG1475	DNA binding
CTZ20_RS10350	COG1192	Involved in chromosome partitioning
CTZ20_RS10360	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CTZ20_RS10375	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CTZ20_RS10380	COG0191	fructose-bisphosphate aldolase activity
CTZ20_RS10400	COG0424	maF-like protein
CTZ20_RS10405	COG2850	peptidyl-arginine hydroxylation
CTZ20_RS10415	COG0640	Transcriptional regulator
CTZ20_RS10425	COG3619	membrane
CTZ20_RS10430	COG3122	Protein conserved in bacteria
CTZ20_RS10435	COG1132	(ABC) transporter
CTZ20_RS10455	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CTZ20_RS10460	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CTZ20_RS10470	COG0506	proline dehydrogenase activity
CTZ20_RS10470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ20_RS10470	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CTZ20_RS10475	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CTZ20_RS10490	COG3698	Phosphodiester glycosidase
CTZ20_RS10500	COG2353	YceI-like domain
CTZ20_RS10510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CTZ20_RS10555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CTZ20_RS10555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CTZ20_RS10580	COG3539	Fimbrial protein
CTZ20_RS10585	COG3121	Chaperone
CTZ20_RS10615	COG0697	spore germination
CTZ20_RS10625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ20_RS10635	COG0583	DNA-binding transcription factor activity
CTZ20_RS10655	COG1309	transcriptional regulator
CTZ20_RS10680	COG1522	sequence-specific DNA binding
CTZ20_RS10690	COG1126	abc transporter atp-binding protein
CTZ20_RS10695	COG0765	amino acid transport
CTZ20_RS10700	COG0765	amino acid transport
CTZ20_RS10730	COG1464	Belongs to the NlpA lipoprotein family
CTZ20_RS10740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CTZ20_RS10745	COG2011	ABC-type metal ion transport system permease component
CTZ20_RS10750	COG0012	GTP binding
CTZ20_RS10775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CTZ20_RS10815	COG0386	Belongs to the glutathione peroxidase family
CTZ20_RS10825	COG0436	Aminotransferase
CTZ20_RS10865	COG3634	alkyl hydroperoxide reductase activity
CTZ20_RS10880	COG0583	DNA-binding transcription factor activity
CTZ20_RS10885	COG0798	PFAM Bile acid sodium symporter
CTZ20_RS10890	COG0640	Transcriptional regulator
CTZ20_RS10905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CTZ20_RS10915	COG0583	DNA-binding transcription factor activity
CTZ20_RS10925	COG1953	Uracil, thiamine, allantoin
CTZ20_RS10935	COG2175	clavaminate synthase activity
CTZ20_RS10940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_RS10945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CTZ20_RS10950	COG4521	taurine ABC transporter
CTZ20_RS10960	COG0477	Major facilitator Superfamily
CTZ20_RS10985	COG1271	oxidase subunit
CTZ20_RS10990	COG1294	oxidase, subunit
CTZ20_RS11000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_RS11020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CTZ20_RS11040	COG3052	prosthetic group binding
CTZ20_RS11045	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CTZ20_RS11055	COG2814	Major facilitator Superfamily
CTZ20_RS11075	COG1346	cytolysis
CTZ20_RS11085	COG0583	DNA-binding transcription factor activity
CTZ20_RS11090	COG0625	glutathione transferase activity
CTZ20_RS11095	COG0625	glutathione transferase activity
CTZ20_RS11100	COG0583	DNA-binding transcription factor activity
CTZ20_RS11115	COG1045	serine acetyltransferase
CTZ20_RS11120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CTZ20_RS11125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CTZ20_RS11135	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS11150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_RS11155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_RS11160	COG1126	abc transporter atp-binding protein
CTZ20_RS11165	COG0765	amino acid transport
CTZ20_RS11170	COG0765	amino acid transport
CTZ20_RS11190	COG0784	Response regulator, receiver
CTZ20_RS11190	COG2205	protein histidine kinase activity
CTZ20_RS11210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ20_RS11230	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS11275	COG0583	DNA-binding transcription factor activity
CTZ20_RS11295	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_RS11300	COG1309	transcriptional regulator
CTZ20_RS11305	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS11310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CTZ20_RS11315	COG1024	Enoyl-CoA hydratase
CTZ20_RS11320	COG4770	biotin carboxylase activity
CTZ20_RS11330	COG0583	DNA-binding transcription factor activity
CTZ20_RS11345	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS11355	COG2814	Major facilitator Superfamily
CTZ20_RS11365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CTZ20_RS11370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CTZ20_RS11375	COG2814	Major facilitator Superfamily
CTZ20_RS11380	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS11385	COG1024	Enoyl-CoA hydratase
CTZ20_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ20_RS11400	COG0183	Belongs to the thiolase family
CTZ20_RS11410	COG2814	Major facilitator Superfamily
CTZ20_RS11420	COG1024	Enoyl-CoA hydratase
CTZ20_RS11435	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS11440	COG2814	Major facilitator Superfamily
CTZ20_RS11445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CTZ20_RS11450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CTZ20_RS11465	COG3842	ATPase activity
CTZ20_RS11470	COG1840	ABC-type Fe3 transport system, periplasmic component
CTZ20_RS11480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_RS11485	COG1414	Transcriptional regulator
CTZ20_RS11495	COG0583	DNA-binding transcription factor activity
CTZ20_RS11500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CTZ20_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS11515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CTZ20_RS11525	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS11530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_RS11535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_RS11540	COG2267	carboxylic ester hydrolase activity
CTZ20_RS11560	COG3038	cytochrome b561
CTZ20_RS11565	COG0753	catalase activity
CTZ20_RS11605	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ20_RS11615	COG3327	negative regulation of DNA-templated transcription, initiation
CTZ20_RS11620	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CTZ20_RS11625	COG0183	Belongs to the thiolase family
CTZ20_RS11630	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ20_RS11635	COG1024	Enoyl-CoA hydratase
CTZ20_RS11640	COG1024	Enoyl-CoA hydratase
CTZ20_RS11645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CTZ20_RS11650	COG2151	metal-sulfur cluster biosynthetic enzyme
CTZ20_RS11655	COG3396	Phenylacetate-CoA oxygenase
CTZ20_RS11660	COG3460	Phenylacetate-CoA oxygenase
CTZ20_RS11665	COG3396	Phenylacetate-CoA oxygenase
CTZ20_RS11670	COG2030	dehydratase
CTZ20_RS11670	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS11675	COG1760	l-serine dehydratase
CTZ20_RS11680	COG0531	amino acid
CTZ20_RS11685	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS11700	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_RS11710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CTZ20_RS11730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_RS11745	COG0789	Transcriptional regulator
CTZ20_RS11770	COG1116	anion transmembrane transporter activity
CTZ20_RS11775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CTZ20_RS11785	COG0864	Transcriptional regulator
CTZ20_RS11805	COG2249	NAD(P)H dehydrogenase (quinone) activity
CTZ20_RS11810	COG0439	Biotin carboxylase
CTZ20_RS11825	COG1063	alcohol dehydrogenase
CTZ20_RS11835	COG1309	transcriptional regulator
CTZ20_RS11860	COG0038	chloride channel
CTZ20_RS11865	COG4770	biotin carboxylase activity
CTZ20_RS11885	COG1914	H( )-stimulated, divalent metal cation uptake system
CTZ20_RS11890	COG0583	DNA-binding transcription factor activity
CTZ20_RS11945	COG1250	3-hydroxyacyl-CoA dehydrogenase
CTZ20_RS11965	COG2814	Major facilitator Superfamily
CTZ20_RS11975	COG1560	Kdo2-lipid A biosynthetic process
CTZ20_RS11985	COG5006	permease, DMT superfamily
CTZ20_RS11990	COG1522	sequence-specific DNA binding
CTZ20_RS12005	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CTZ20_RS12015	COG4122	O-methyltransferase activity
CTZ20_RS12045	COG1538	Outer membrane efflux protein
CTZ20_RS12050	COG1137	ATPase activity
CTZ20_RS12055	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CTZ20_RS12065	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CTZ20_RS12070	COG0517	IMP dehydrogenase activity
CTZ20_RS12070	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CTZ20_RS12110	COG2814	Major facilitator Superfamily
CTZ20_RS12150	COG1278	Cold shock
CTZ20_RS12155	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS12190	COG1570	exodeoxyribonuclease VII activity
CTZ20_RS12245	COG0583	DNA-binding transcription factor activity
CTZ20_RS12250	COG4638	Rieske (2fe-2S)
CTZ20_RS12255	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CTZ20_RS12260	COG0543	2 iron, 2 sulfur cluster binding
CTZ20_RS12260	COG0633	Ferredoxin
CTZ20_RS12265	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS12270	COG3135	benzoate transporter
CTZ20_RS12275	COG2814	Major facilitator Superfamily
CTZ20_RS12290	COG1643	Atp-dependent helicase
CTZ20_RS12295	COG0450	alkyl hydroperoxide reductase
CTZ20_RS12305	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CTZ20_RS12315	COG3634	alkyl hydroperoxide reductase activity
CTZ20_RS12335	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CTZ20_RS12340	COG0625	glutathione transferase activity
CTZ20_RS12350	COG2885	chlorophyll binding
CTZ20_RS12385	COG0542	response to heat
CTZ20_RS12400	COG1765	OsmC-like protein
CTZ20_RS12415	COG0667	Aldo Keto reductase
CTZ20_RS12430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CTZ20_RS12440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CTZ20_RS12450	COG0527	aspartate kinase activity
CTZ20_RS12460	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CTZ20_RS12470	COG3038	cytochrome b561
CTZ20_RS12475	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CTZ20_RS12565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
CTZ20_RS12605	COG1113	amino acid transport
CTZ20_RS12625	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS12645	COG0531	amino acid
CTZ20_RS12655	COG1113	amino acid transport
CTZ20_RS12700	COG3209	COG3209 Rhs family protein
CTZ20_RS12725	COG4269	membrane
CTZ20_RS12740	COG1902	pentaerythritol trinitrate reductase activity
CTZ20_RS12740	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_RS12750	COG2203	Gaf domain
CTZ20_RS12750	COG3706	GGDEF domain
CTZ20_RS12750	COG4251	negative regulation of phosphorylation
CTZ20_RS12750	COG5001	Diguanylate cyclase
CTZ20_RS12760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_RS12780	COG4172	Belongs to the ABC transporter superfamily
CTZ20_RS12785	COG4239	(ABC) transporter, permease
CTZ20_RS12790	COG4174	ABC transporter (Permease)
CTZ20_RS12800	COG0741	lytic transglycosylase activity
CTZ20_RS12800	COG1388	LysM domain
CTZ20_RS12800	COG0741	lytic transglycosylase activity
CTZ20_RS12800	COG1388	LysM domain
CTZ20_RS12805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_RS12845	COG0583	DNA-binding transcription factor activity
CTZ20_RS12850	COG1279	arginine transmembrane transporter activity
CTZ20_RS12870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_RS12875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_RS12880	COG0006	proline dipeptidase activity
CTZ20_RS12915	COG2194	sulfuric ester hydrolase activity
CTZ20_RS12960	COG0739	heme binding
CTZ20_RS13325	COG0741	lytic transglycosylase activity
CTZ20_RS13325	COG0739	heme binding
CTZ20_RS13325	COG1196	nuclear chromosome segregation
CTZ20_RS13380	COG4695	Portal protein
CTZ20_RS13475	COG0305	Participates in initiation and elongation during chromosome replication
CTZ20_RS13495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CTZ20_RS13555	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CTZ20_RS13580	COG3384	dioxygenase
CTZ20_RS13590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CTZ20_RS13595	COG2878	Part of a membrane complex involved in electron transport
CTZ20_RS13600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CTZ20_RS13625	COG0768	penicillin binding
CTZ20_RS13630	COG0742	ribosomal rna small subunit methyltransferase
CTZ20_RS13645	COG0830	nickel cation binding
CTZ20_RS13655	COG0804	urea catabolic process
CTZ20_RS13695	COG1253	flavin adenine dinucleotide binding
CTZ20_RS13705	COG2851	Citrate transporter
CTZ20_RS13755	COG1773	rubredoxin
CTZ20_RS13760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CTZ20_RS13770	COG0583	DNA-binding transcription factor activity
CTZ20_RS13800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CTZ20_RS13805	COG4181	ATPase activity
CTZ20_RS13850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CTZ20_RS13870	COG0306	phosphate transporter
CTZ20_RS13880	COG3958	Transketolase
CTZ20_RS13885	COG3959	Transketolase, thiamine diphosphate binding domain
CTZ20_RS13890	COG2271	Major facilitator Superfamily
CTZ20_RS13895	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS13900	COG0583	DNA-binding transcription factor activity
CTZ20_RS13920	COG2223	nitrite transmembrane transporter activity
CTZ20_RS13925	COG2207	Transcriptional regulator
CTZ20_RS13930	COG2066	Belongs to the glutaminase family
CTZ20_RS13935	COG0242	peptide deformylase activity
CTZ20_RS13940	COG0477	Major facilitator Superfamily
CTZ20_RS13950	COG0028	Belongs to the TPP enzyme family
CTZ20_RS13965	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS13970	COG2267	carboxylic ester hydrolase activity
CTZ20_RS13980	COG2271	Major facilitator Superfamily
CTZ20_RS13985	COG0446	pyridine nucleotide-disulphide oxidoreductase
CTZ20_RS13995	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS14015	COG1414	Transcriptional regulator
CTZ20_RS14030	COG1024	Enoyl-CoA hydratase
CTZ20_RS14040	COG1215	transferase activity, transferring glycosyl groups
CTZ20_RS14045	COG0726	polysaccharide deacetylase
CTZ20_RS14045	COG1649	PFAM Uncharacterised BCR, COG1649
CTZ20_RS14055	COG4681	YaeQ
CTZ20_RS14065	COG0523	cobalamin synthesis protein
CTZ20_RS14075	COG1607	acyl-coa hydrolase
CTZ20_RS14085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_RS14090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CTZ20_RS14095	COG1309	transcriptional regulator
CTZ20_RS14120	COG2040	homocysteine
CTZ20_RS14125	COG0531	amino acid
CTZ20_RS14180	COG1595	DNA-templated transcription, initiation
CTZ20_RS14190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_RS14195	COG0477	Major facilitator Superfamily
CTZ20_RS14330	COG0592	DNA-directed DNA polymerase activity
CTZ20_RS14370	COG2026	Addiction module toxin, RelE StbE family
CTZ20_RS14520	COG3755	Protein conserved in bacteria
CTZ20_RS14565	COG1484	DNA-dependent DNA replication
CTZ20_RS14675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CTZ20_RS14705	COG0405	Gamma-glutamyltransferase
CTZ20_RS14710	COG2814	Major facilitator Superfamily
CTZ20_RS14720	COG2050	protein possibly involved in aromatic compounds catabolism
CTZ20_RS14735	COG1090	epimerase
CTZ20_RS14755	COG0420	3'-5' exonuclease activity
CTZ20_RS14780	COG0735	belongs to the Fur family
CTZ20_RS14785	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CTZ20_RS14810	COG0121	glutamine amidotransferase
CTZ20_RS14825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ20_RS14835	COG0210	DNA helicase
CTZ20_RS14840	COG2885	chlorophyll binding
CTZ20_RS14845	COG0204	Acyl-transferase
CTZ20_RS14860	COG2894	cell division
CTZ20_RS14885	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS14890	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CTZ20_RS14890	COG1674	ftsk spoiiie
CTZ20_RS14895	COG0492	ferredoxin-NADP+ reductase activity
CTZ20_RS14900	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CTZ20_RS14910	COG0456	acetyltransferase
CTZ20_RS14955	COG1981	membrane
CTZ20_RS14970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ20_RS14970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CTZ20_RS14990	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS15000	COG0657	acetylesterase activity
CTZ20_RS15010	COG0473	3-isopropylmalate dehydrogenase activity
CTZ20_RS15015	COG0583	DNA-binding transcription factor activity
CTZ20_RS15035	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CTZ20_RS15060	COG0564	pseudouridine synthase activity
CTZ20_RS15070	COG0358	DNA primase activity
CTZ20_RS15085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CTZ20_RS15115	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CTZ20_RS15145	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CTZ20_RS15155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CTZ20_RS15155	COG0351	phosphomethylpyrimidine kinase
CTZ20_RS15155	COG0352	thiamine-phosphate diphosphorylase activity
CTZ20_RS15160	COG1652	LysM domain
CTZ20_RS15185	COG1399	metal-binding, possibly nucleic acid-binding protein
CTZ20_RS15190	COG3101	peptidyl-lysine hydroxylation
CTZ20_RS15195	COG0009	L-threonylcarbamoyladenylate synthase
CTZ20_RS15200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CTZ20_RS15205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CTZ20_RS15220	COG4106	trans-aconitate 2-methyltransferase activity
CTZ20_RS15235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_RS15235	COG0596	Alpha beta hydrolase
CTZ20_RS15235	COG2226	methyltransferase
CTZ20_RS15240	COG1877	trehalose-phosphatase activity
CTZ20_RS15245	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CTZ20_RS15250	COG2223	nitrite transmembrane transporter activity
CTZ20_RS15270	COG1196	nuclear chromosome segregation
CTZ20_RS15280	COG0730	response to heat
CTZ20_RS15295	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CTZ20_RS15305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ20_RS15365	COG0489	protein tyrosine kinase activity
CTZ20_RS15375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_RS15375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_RS15405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CTZ20_RS15410	COG2081	HI0933 family
CTZ20_RS15420	COG0668	transmembrane transport
CTZ20_RS15440	COG0583	DNA-binding transcription factor activity
CTZ20_RS15460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CTZ20_RS15465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ20_RS15495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CTZ20_RS15535	COG0745	RESPONSE REGULATOR receiver
CTZ20_RS15555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CTZ20_RS15565	COG2205	protein histidine kinase activity
CTZ20_RS15635	COG4993	Dehydrogenase
CTZ20_RS15655	COG0384	phenazine biosynthesis protein PhzF
CTZ20_RS15685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CTZ20_RS15700	COG0583	DNA-binding transcription factor activity
CTZ20_RS15730	COG0583	DNA-binding transcription factor activity
CTZ20_RS15750	COG0583	DNA-binding transcription factor activity
CTZ20_RS15755	COG1053	succinate dehydrogenase
CTZ20_RS15765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CTZ20_RS15770	COG2814	Major facilitator Superfamily
CTZ20_RS15775	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS15780	COG0583	DNA-binding transcription factor activity
CTZ20_RS15785	COG1063	alcohol dehydrogenase
CTZ20_RS15815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CTZ20_RS15820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CTZ20_RS15825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ20_RS15840	COG3667	copper resistance
CTZ20_RS15845	COG2132	Multicopper oxidase
CTZ20_RS15855	COG0561	phosphatase activity
CTZ20_RS15860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CTZ20_RS15885	COG1214	PFAM Peptidase M22, glycoprotease
CTZ20_RS15935	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CTZ20_RS15945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CTZ20_RS15950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CTZ20_RS15955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CTZ20_RS16015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CTZ20_RS16025	COG1846	Transcriptional regulator
CTZ20_RS16030	COG1764	response to oxidative stress
CTZ20_RS16070	COG0037	tRNA processing
CTZ20_RS16080	COG0248	Ppx GppA phosphatase
CTZ20_RS16110	COG0072	phenylalanine-tRNA ligase activity
CTZ20_RS16150	COG1238	metal cluster binding
CTZ20_RS16155	COG0625	glutathione transferase activity
CTZ20_RS16175	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_RS16180	COG3028	Belongs to the UPF0307 family
CTZ20_RS16185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CTZ20_RS16205	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CTZ20_RS16210	COG0617	tRNA 3'-terminal CCA addition
CTZ20_RS16215	COG1555	photosystem II stabilization
CTZ20_RS16220	COG3956	TIGRFAM MazG family protein
CTZ20_RS16230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CTZ20_RS16250	COG0784	Response regulator, receiver
CTZ20_RS16250	COG2205	protein histidine kinase activity
CTZ20_RS16250	COG5002	protein histidine kinase activity
CTZ20_RS16255	COG1024	Enoyl-CoA hydratase
CTZ20_RS16260	COG2084	Dehydrogenase
CTZ20_RS16265	COG3622	Belongs to the hyi family
CTZ20_RS16295	COG0697	spore germination
CTZ20_RS16305	COG2814	Major facilitator Superfamily
CTZ20_RS16310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CTZ20_RS16320	COG0583	DNA-binding transcription factor activity
CTZ20_RS16330	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CTZ20_RS16345	COG0084	hydrolase, TatD family'
CTZ20_RS16360	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CTZ20_RS16395	COG0440	acetolactate synthase activity
CTZ20_RS16400	COG0028	Belongs to the TPP enzyme family
CTZ20_RS16425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CTZ20_RS16430	COG0577	efflux transmembrane transporter activity
CTZ20_RS16430	COG1136	(ABC) transporter
CTZ20_RS16435	COG1538	Outer membrane efflux protein
CTZ20_RS16450	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CTZ20_RS16455	COG1162	GTPase activity
CTZ20_RS16465	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CTZ20_RS16485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CTZ20_RS16490	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS16530	COG2986	histidine ammonia-lyase
CTZ20_RS16545	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_RS16555	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ20_RS16600	COG1426	Protein conserved in bacteria
CTZ20_RS16635	COG0793	Belongs to the peptidase S41A family
CTZ20_RS16650	COG2267	carboxylic ester hydrolase activity
CTZ20_RS16660	COG1012	belongs to the aldehyde dehydrogenase family
CTZ20_RS16665	COG3265	gluconokinase activity
CTZ20_RS16675	COG0800	Aldolase
CTZ20_RS16690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CTZ20_RS16695	COG0280	phosphate acetyltransferase
CTZ20_RS16695	COG0857	belongs to the CobB CobQ family
CTZ20_RS16700	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ20_RS16700	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CTZ20_RS16720	COG0740	serine-type endopeptidase activity
CTZ20_RS16730	COG4774	siderophore transport
CTZ20_RS16740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CTZ20_RS16750	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CTZ20_RS16750	COG2813	Specifically methylates the guanine in position
CTZ20_RS16850	COG0788	formyltetrahydrofolate deformylase activity
CTZ20_RS16875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_RS16875	COG4651	solute:proton antiporter activity
CTZ20_RS16895	COG0724	RNA recognition motif
CTZ20_RS16900	COG0210	DNA helicase
CTZ20_RS16925	COG1733	regulation of RNA biosynthetic process
CTZ20_RS16935	COG2900	Belongs to the SlyX family
CTZ20_RS16940	COG0488	(ABC) transporter
CTZ20_RS16945	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS16950	COG1560	Kdo2-lipid A biosynthetic process
CTZ20_RS16960	COG1301	dicarboxylic acid transport
CTZ20_RS17015	COG0473	3-isopropylmalate dehydrogenase activity
CTZ20_RS17080	COG0583	DNA-binding transcription factor activity
CTZ20_RS17090	COG0625	glutathione transferase activity
CTZ20_RS17095	COG2378	regulation of single-species biofilm formation
CTZ20_RS17100	COG0546	phosphoglycolate phosphatase activity
CTZ20_RS17115	COG1530	ribonuclease E activity
CTZ20_RS17120	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_RS17135	COG0583	DNA-binding transcription factor activity
CTZ20_RS17140	COG4221	oxidoreductase activity
CTZ20_RS17145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CTZ20_RS17155	COG0534	Mate efflux family protein
CTZ20_RS17170	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CTZ20_RS17210	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CTZ20_RS17215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CTZ20_RS17230	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CTZ20_RS17240	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CTZ20_RS17240	COG0644	oxidoreductase
CTZ20_RS17245	COG0425	Belongs to the sulfur carrier protein TusA family
CTZ20_RS17250	COG4535	Mg2 and Co2 transporter CorC
CTZ20_RS17260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CTZ20_RS17280	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CTZ20_RS17285	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CTZ20_RS17285	COG0475	glutathione-regulated potassium exporter activity
CTZ20_RS17290	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CTZ20_RS17300	COG0484	heat shock protein binding
CTZ20_RS17305	COG0789	Transcriptional regulator
CTZ20_RS17310	COG0598	Magnesium transport protein CorA
CTZ20_RS17325	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CTZ20_RS17330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CTZ20_RS17335	COG1074	ATP-dependent DNA helicase activity
CTZ20_RS17340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CTZ20_RS17360	COG2226	methyltransferase
CTZ20_RS17375	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CTZ20_RS17380	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CTZ20_RS17395	COG2111	Na H antiporter
CTZ20_RS17395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CTZ20_RS17400	COG1006	Multisubunit Na H antiporter MnhC subunit
CTZ20_RS17405	COG0651	ATP synthesis coupled electron transport
CTZ20_RS17410	COG1863	multisubunit Na H antiporter MnhE subunit
CTZ20_RS17415	COG2212	antiporter activity
CTZ20_RS17420	COG1320	monovalent cation:proton antiporter activity
CTZ20_RS17435	COG0195	Participates in both transcription termination and antitermination
CTZ20_RS17485	COG0237	dephospho-CoA kinase activity
CTZ20_RS17495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CTZ20_RS17510	COG0497	DNA recombination
CTZ20_RS17520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CTZ20_RS17550	COG2169	Transcriptional regulator
CTZ20_RS17550	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CTZ20_RS17555	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CTZ20_RS17630	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CTZ20_RS17645	COG0326	Molecular chaperone. Has ATPase activity
CTZ20_RS17660	COG2056	Na+-H+ antiporter family
CTZ20_RS17665	COG0596	Alpha beta hydrolase
CTZ20_RS17760	COG0546	phosphoglycolate phosphatase activity
CTZ20_RS17765	COG1716	ATPase activity
CTZ20_RS17810	COG0181	hydroxymethylbilane synthase activity
CTZ20_RS17820	COG3275	phosphorelay sensor kinase activity
CTZ20_RS17840	COG1538	Outer membrane efflux protein
CTZ20_RS17850	COG0697	spore germination
CTZ20_RS17875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CTZ20_RS17880	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CTZ20_RS17885	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CTZ20_RS17890	COG0772	Belongs to the SEDS family
CTZ20_RS17915	COG4974	Belongs to the 'phage' integrase family
CTZ20_RS17920	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_RS17930	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CTZ20_RS17940	COG2197	response regulator
CTZ20_RS17955	COG0793	Belongs to the peptidase S41A family
CTZ20_RS17960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CTZ20_RS17965	COG0795	lipopolysaccharide-transporting ATPase activity
CTZ20_RS18005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ20_RS18005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CTZ20_RS18015	COG0004	ammonium transporteR
CTZ20_RS18020	COG0347	Belongs to the P(II) protein family
CTZ20_RS18030	COG0606	chelatase, subunit chli
CTZ20_RS18040	COG0659	secondary active sulfate transmembrane transporter activity
CTZ20_RS18045	COG0589	response to stress
CTZ20_RS18075	COG0606	chelatase, subunit chli
CTZ20_RS18080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CTZ20_RS18090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CTZ20_RS18105	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CTZ20_RS18120	COG0318	PFAM AMP-dependent synthetase and ligase
CTZ20_RS18130	COG0477	Major facilitator Superfamily
CTZ20_RS18135	COG2860	membrane
CTZ20_RS18145	COG1253	flavin adenine dinucleotide binding
CTZ20_RS18165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CTZ20_RS18200	COG0655	NAD(P)H dehydrogenase (quinone) activity
CTZ20_RS18210	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CTZ20_RS18245	COG1309	transcriptional regulator
CTZ20_RS18280	COG0758	DNA mediated transformation
CTZ20_RS18290	COG0697	spore germination
CTZ20_RS18295	COG1309	transcriptional regulator
CTZ20_RS18310	COG0386	Belongs to the glutathione peroxidase family
CTZ20_RS18375	COG1121	(ABC) transporter
CTZ20_RS18380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CTZ20_RS18385	COG1280	lysine exporter protein (LysE YggA)
CTZ20_RS18390	COG2837	iron assimilation
CTZ20_RS18395	COG0281	malic enzyme
CTZ20_RS18440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CTZ20_RS18440	COG0519	Catalyzes the synthesis of GMP from XMP
CTZ20_RS18445	COG4399	Belongs to the UPF0754 family
CTZ20_RS18450	COG2259	Doxx family
CTZ20_RS18455	COG0586	Pfam SNARE associated Golgi protein
CTZ20_RS18470	COG1192	Involved in chromosome partitioning
CTZ20_RS18480	COG0271	Belongs to the BolA IbaG family
CTZ20_RS18520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CTZ20_RS18520	COG3321	synthase
CTZ20_RS18520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CTZ20_RS18520	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CTZ20_RS18525	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS18540	COG2197	response regulator
CTZ20_RS18550	COG3916	Acyl-homoserine-lactone synthase
CTZ20_RS18555	COG0477	Major facilitator Superfamily
CTZ20_RS18560	COG1024	Enoyl-CoA hydratase
CTZ20_RS18565	COG1024	Enoyl-CoA hydratase
CTZ20_RS18570	COG1960	acyl-CoA dehydrogenase activity
CTZ20_RS18575	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CTZ20_RS18600	COG1113	amino acid transport
CTZ20_RS18605	COG1113	amino acid transport
CTZ20_RS18610	COG0251	oxidation-reduction process
CTZ20_RS18650	COG0564	pseudouridine synthase activity
CTZ20_RS18720	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CTZ20_RS18735	COG1802	Transcriptional regulator
CTZ20_RS18745	COG1448	Aminotransferase
CTZ20_RS18750	COG0277	FAD linked oxidase domain protein
CTZ20_RS18760	COG2186	Transcriptional regulator
CTZ20_RS18770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CTZ20_RS18775	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CTZ20_RS18790	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CTZ20_RS18795	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CTZ20_RS18800	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CTZ20_RS18860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CTZ20_RS18865	COG1596	polysaccharide export
CTZ20_RS18890	COG0728	peptidoglycan biosynthetic process
CTZ20_RS18895	COG3023	N-Acetylmuramoyl-L-alanine amidase
CTZ20_RS18955	COG0546	phosphoglycolate phosphatase activity
CTZ20_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
CTZ20_RS18980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_RS18985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CTZ20_RS18990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CTZ20_RS18995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CTZ20_RS19000	COG1116	anion transmembrane transporter activity
CTZ20_RS19005	COG1309	transcriptional regulator
CTZ20_RS19010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CTZ20_RS19020	COG0196	riboflavin kinase activity
CTZ20_RS19025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CTZ20_RS19035	COG1047	Peptidyl-prolyl cis-trans
CTZ20_RS19075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CTZ20_RS19080	COG0657	acetylesterase activity
CTZ20_RS19130	COG2951	lytic endotransglycosylase activity
CTZ20_RS19135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CTZ20_RS19155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CTZ20_RS19165	COG0671	phosphoesterase, PA-phosphatase related
CTZ20_RS19170	COG0861	Integral membrane protein TerC family
CTZ20_RS19180	COG0754	glutathionylspermidine amidase activity
CTZ20_RS19190	COG0402	S-adenosylhomocysteine deaminase activity
CTZ20_RS19205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CTZ20_RS19210	COG1230	cation diffusion facilitator family transporter
CTZ20_RS19225	COG0706	membrane insertase activity