locus-tag	class	description
F9K57_RS00055	COG0772	Belongs to the SEDS family
F9K57_RS00060	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9K57_RS00065	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9K57_RS00070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_RS00075	COG0494	nUDIX hydrolase
F9K57_RS00095	COG0697	spore germination
F9K57_RS00100	COG1538	Outer membrane efflux protein
F9K57_RS00120	COG3275	phosphorelay sensor kinase activity
F9K57_RS00130	COG0181	hydroxymethylbilane synthase activity
F9K57_RS00175	COG1716	ATPase activity
F9K57_RS00180	COG0546	phosphoglycolate phosphatase activity
F9K57_RS00280	COG2056	Na+-H+ antiporter family
F9K57_RS00295	COG0326	Molecular chaperone. Has ATPase activity
F9K57_RS00310	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F9K57_RS00370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F9K57_RS00375	COG2169	Transcriptional regulator
F9K57_RS00375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9K57_RS00405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F9K57_RS00415	COG0497	DNA recombination
F9K57_RS00430	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9K57_RS00490	COG0195	Participates in both transcription termination and antitermination
F9K57_RS00510	COG2212	antiporter activity
F9K57_RS00520	COG0651	ATP synthesis coupled electron transport
F9K57_RS00525	COG1006	Multisubunit Na H antiporter MnhC subunit
F9K57_RS00530	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9K57_RS00530	COG2111	Na H antiporter
F9K57_RS00545	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F9K57_RS00565	COG2226	methyltransferase
F9K57_RS00585	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F9K57_RS00590	COG1074	ATP-dependent DNA helicase activity
F9K57_RS00595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9K57_RS00620	COG0789	Transcriptional regulator
F9K57_RS00640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9K57_RS00640	COG0475	glutathione-regulated potassium exporter activity
F9K57_RS00645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F9K57_RS00665	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_RS00675	COG4535	Mg2 and Co2 transporter CorC
F9K57_RS00680	COG0425	Belongs to the sulfur carrier protein TusA family
F9K57_RS00690	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F9K57_RS00690	COG0644	oxidoreductase
F9K57_RS00700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F9K57_RS00715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_RS00720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F9K57_RS00760	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F9K57_RS00775	COG0534	Mate efflux family protein
F9K57_RS00785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F9K57_RS00790	COG4221	oxidoreductase activity
F9K57_RS00795	COG0583	DNA-binding transcription factor activity
F9K57_RS00815	COG1530	ribonuclease E activity
F9K57_RS00825	COG0546	phosphoglycolate phosphatase activity
F9K57_RS00830	COG2378	regulation of single-species biofilm formation
F9K57_RS00835	COG0625	glutathione transferase activity
F9K57_RS00845	COG0583	DNA-binding transcription factor activity
F9K57_RS00910	COG0473	3-isopropylmalate dehydrogenase activity
F9K57_RS00965	COG1301	dicarboxylic acid transport
F9K57_RS00975	COG1560	Kdo2-lipid A biosynthetic process
F9K57_RS00980	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS01000	COG1733	regulation of RNA biosynthetic process
F9K57_RS01025	COG0210	DNA helicase
F9K57_RS01030	COG0724	RNA recognition motif
F9K57_RS01050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F9K57_RS01050	COG4651	solute:proton antiporter activity
F9K57_RS01055	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F9K57_RS01060	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F9K57_RS01075	COG0788	formyltetrahydrofolate deformylase activity
F9K57_RS01175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_RS01175	COG2813	Specifically methylates the guanine in position
F9K57_RS01185	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9K57_RS01195	COG4774	siderophore transport
F9K57_RS01205	COG0740	serine-type endopeptidase activity
F9K57_RS01225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F9K57_RS01225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F9K57_RS01230	COG0857	belongs to the CobB CobQ family
F9K57_RS01230	COG0280	phosphate acetyltransferase
F9K57_RS01235	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F9K57_RS01245	COG0800	Aldolase
F9K57_RS01255	COG3265	gluconokinase activity
F9K57_RS01260	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS01270	COG2267	carboxylic ester hydrolase activity
F9K57_RS01285	COG0793	Belongs to the peptidase S41A family
F9K57_RS01320	COG1426	Protein conserved in bacteria
F9K57_RS01360	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F9K57_RS01370	COG1162	GTPase activity
F9K57_RS01375	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F9K57_RS01390	COG1538	Outer membrane efflux protein
F9K57_RS01395	COG0577	efflux transmembrane transporter activity
F9K57_RS01395	COG1136	(ABC) transporter
F9K57_RS01400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS01425	COG0028	Belongs to the TPP enzyme family
F9K57_RS01430	COG0440	acetolactate synthase activity
F9K57_RS01460	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F9K57_RS01475	COG0084	hydrolase, TatD family'
F9K57_RS01490	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F9K57_RS01500	COG0583	DNA-binding transcription factor activity
F9K57_RS01510	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9K57_RS01515	COG2814	Major facilitator Superfamily
F9K57_RS01530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F9K57_RS01535	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F9K57_RS01540	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F9K57_RS01555	COG3622	Belongs to the hyi family
F9K57_RS01560	COG2084	Dehydrogenase
F9K57_RS01565	COG1024	Enoyl-CoA hydratase
F9K57_RS01570	COG5002	protein histidine kinase activity
F9K57_RS01570	COG0784	Response regulator, receiver
F9K57_RS01570	COG2205	protein histidine kinase activity
F9K57_RS01590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9K57_RS01600	COG3956	TIGRFAM MazG family protein
F9K57_RS01605	COG1555	photosystem II stabilization
F9K57_RS01610	COG0617	tRNA 3'-terminal CCA addition
F9K57_RS01615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F9K57_RS01635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9K57_RS01640	COG3028	Belongs to the UPF0307 family
F9K57_RS01645	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_RS01660	COG0625	glutathione transferase activity
F9K57_RS01665	COG1238	metal cluster binding
F9K57_RS01680	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F9K57_RS01700	COG0072	phenylalanine-tRNA ligase activity
F9K57_RS01730	COG0248	Ppx GppA phosphatase
F9K57_RS01740	COG0037	tRNA processing
F9K57_RS01780	COG1764	response to oxidative stress
F9K57_RS01785	COG1846	Transcriptional regulator
F9K57_RS01795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9K57_RS01855	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F9K57_RS01860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F9K57_RS01865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F9K57_RS01925	COG1214	PFAM Peptidase M22, glycoprotease
F9K57_RS01950	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F9K57_RS01955	COG0561	phosphatase activity
F9K57_RS01965	COG2132	Multicopper oxidase
F9K57_RS01970	COG3667	copper resistance
F9K57_RS01985	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F9K57_RS01990	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F9K57_RS01995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F9K57_RS02025	COG1063	alcohol dehydrogenase
F9K57_RS02030	COG0583	DNA-binding transcription factor activity
F9K57_RS02035	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS02040	COG2814	Major facilitator Superfamily
F9K57_RS02045	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F9K57_RS02050	COG1309	transcriptional regulator
F9K57_RS02065	COG1053	succinate dehydrogenase
F9K57_RS02070	COG0583	DNA-binding transcription factor activity
F9K57_RS02085	COG0583	DNA-binding transcription factor activity
F9K57_RS02115	COG1473	amidohydrolase
F9K57_RS02135	COG0583	DNA-binding transcription factor activity
F9K57_RS02145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F9K57_RS02150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS02180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F9K57_RS02200	COG0745	RESPONSE REGULATOR receiver
F9K57_RS02205	COG2205	protein histidine kinase activity
F9K57_RS02240	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F9K57_RS02270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F9K57_RS02275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F9K57_RS02295	COG0583	DNA-binding transcription factor activity
F9K57_RS02315	COG0668	transmembrane transport
F9K57_RS02325	COG2081	HI0933 family
F9K57_RS02330	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F9K57_RS02360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_RS02360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F9K57_RS02370	COG0489	protein tyrosine kinase activity
F9K57_RS02420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F9K57_RS02430	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F9K57_RS02445	COG0730	response to heat
F9K57_RS02455	COG1196	nuclear chromosome segregation
F9K57_RS02475	COG2223	nitrite transmembrane transporter activity
F9K57_RS02480	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F9K57_RS02485	COG1877	trehalose-phosphatase activity
F9K57_RS02490	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_RS02490	COG0596	Alpha beta hydrolase
F9K57_RS02490	COG2226	methyltransferase
F9K57_RS02505	COG4106	trans-aconitate 2-methyltransferase activity
F9K57_RS02520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F9K57_RS02525	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F9K57_RS02530	COG0009	L-threonylcarbamoyladenylate synthase
F9K57_RS02535	COG3101	peptidyl-lysine hydroxylation
F9K57_RS02540	COG1399	metal-binding, possibly nucleic acid-binding protein
F9K57_RS02565	COG1652	LysM domain
F9K57_RS02570	COG0351	phosphomethylpyrimidine kinase
F9K57_RS02570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9K57_RS02570	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_RS02580	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F9K57_RS02610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9K57_RS02640	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F9K57_RS02655	COG0358	DNA primase activity
F9K57_RS02665	COG0564	pseudouridine synthase activity
F9K57_RS02690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9K57_RS02710	COG0583	DNA-binding transcription factor activity
F9K57_RS02715	COG0473	3-isopropylmalate dehydrogenase activity
F9K57_RS02735	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS02755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F9K57_RS02755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F9K57_RS02815	COG0456	acetyltransferase
F9K57_RS02825	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F9K57_RS02830	COG0492	ferredoxin-NADP+ reductase activity
F9K57_RS02835	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F9K57_RS02835	COG1674	ftsk spoiiie
F9K57_RS02840	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS02860	COG2894	cell division
F9K57_RS02875	COG0204	Acyl-transferase
F9K57_RS02880	COG2885	chlorophyll binding
F9K57_RS02885	COG0210	DNA helicase
F9K57_RS02910	COG0121	glutamine amidotransferase
F9K57_RS02930	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9K57_RS02935	COG0735	belongs to the Fur family
F9K57_RS02960	COG0420	3'-5' exonuclease activity
F9K57_RS02980	COG1090	epimerase
F9K57_RS02995	COG2050	protein possibly involved in aromatic compounds catabolism
F9K57_RS03005	COG2814	Major facilitator Superfamily
F9K57_RS03255	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9K57_RS03260	COG0582	viral genome integration into host DNA
F9K57_RS03315	COG0084	hydrolase, TatD family'
F9K57_RS03335	COG0477	Major facilitator Superfamily
F9K57_RS03340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_RS03350	COG1595	DNA-templated transcription, initiation
F9K57_RS03405	COG0531	amino acid
F9K57_RS03410	COG2040	homocysteine
F9K57_RS03435	COG1309	transcriptional regulator
F9K57_RS03440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_RS03445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_RS03455	COG1607	acyl-coa hydrolase
F9K57_RS03465	COG0523	cobalamin synthesis protein
F9K57_RS03475	COG4681	YaeQ
F9K57_RS03485	COG0726	polysaccharide deacetylase
F9K57_RS03485	COG1649	PFAM Uncharacterised BCR, COG1649
F9K57_RS03490	COG1215	transferase activity, transferring glycosyl groups
F9K57_RS03500	COG1024	Enoyl-CoA hydratase
F9K57_RS03515	COG1414	Transcriptional regulator
F9K57_RS03535	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS03545	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_RS03550	COG2271	Major facilitator Superfamily
F9K57_RS03560	COG2267	carboxylic ester hydrolase activity
F9K57_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS03580	COG0028	Belongs to the TPP enzyme family
F9K57_RS03590	COG0477	Major facilitator Superfamily
F9K57_RS03595	COG0242	peptide deformylase activity
F9K57_RS03600	COG2066	Belongs to the glutaminase family
F9K57_RS03605	COG2207	Transcriptional regulator
F9K57_RS03610	COG2223	nitrite transmembrane transporter activity
F9K57_RS03625	COG0583	DNA-binding transcription factor activity
F9K57_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS03635	COG2271	Major facilitator Superfamily
F9K57_RS03640	COG3959	Transketolase, thiamine diphosphate binding domain
F9K57_RS03645	COG3958	Transketolase
F9K57_RS03675	COG0306	phosphate transporter
F9K57_RS03695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F9K57_RS03740	COG4181	ATPase activity
F9K57_RS03745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F9K57_RS03775	COG0583	DNA-binding transcription factor activity
F9K57_RS03785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_RS03790	COG1773	rubredoxin
F9K57_RS03840	COG2851	Citrate transporter
F9K57_RS03845	COG1253	flavin adenine dinucleotide binding
F9K57_RS03885	COG0804	urea catabolic process
F9K57_RS03895	COG0830	nickel cation binding
F9K57_RS03910	COG0742	ribosomal rna small subunit methyltransferase
F9K57_RS03915	COG0768	penicillin binding
F9K57_RS03940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F9K57_RS03945	COG2878	Part of a membrane complex involved in electron transport
F9K57_RS03950	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9K57_RS03960	COG3384	dioxygenase
F9K57_RS03980	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F9K57_RS04140	COG5410	chromosome segregation
F9K57_RS04245	COG0739	heme binding
F9K57_RS04245	COG0741	lytic transglycosylase activity
F9K57_RS04245	COG1196	nuclear chromosome segregation
F9K57_RS04345	COG0006	proline dipeptidase activity
F9K57_RS04350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_RS04355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_RS04375	COG1279	arginine transmembrane transporter activity
F9K57_RS04380	COG0583	DNA-binding transcription factor activity
F9K57_RS04420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9K57_RS04425	COG0741	lytic transglycosylase activity
F9K57_RS04425	COG1388	LysM domain
F9K57_RS04425	COG0741	lytic transglycosylase activity
F9K57_RS04425	COG1388	LysM domain
F9K57_RS04435	COG4174	ABC transporter (Permease)
F9K57_RS04440	COG4239	(ABC) transporter, permease
F9K57_RS04445	COG4172	Belongs to the ABC transporter superfamily
F9K57_RS04470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F9K57_RS04480	COG5001	Diguanylate cyclase
F9K57_RS04480	COG4251	negative regulation of phosphorylation
F9K57_RS04480	COG3706	GGDEF domain
F9K57_RS04480	COG2203	Gaf domain
F9K57_RS04490	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_RS04490	COG1902	pentaerythritol trinitrate reductase activity
F9K57_RS04510	COG3501	Rhs element vgr protein
F9K57_RS04515	COG3209	COG3209 Rhs family protein
F9K57_RS04555	COG1113	amino acid transport
F9K57_RS04585	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS04605	COG1113	amino acid transport
F9K57_RS04610	COG2831	hemolysin activation secretion protein
F9K57_RS04650	COG0697	spore germination
F9K57_RS04655	COG2721	sulfolactate sulfo-lyase activity
F9K57_RS04660	COG2271	Major facilitator Superfamily
F9K57_RS04665	COG4948	Mandelate Racemase Muconate Lactonizing
F9K57_RS04675	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS04680	COG2186	Transcriptional regulator
F9K57_RS04705	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS04715	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS04720	COG1024	Enoyl-CoA hydratase
F9K57_RS04725	COG2814	Major facilitator Superfamily
F9K57_RS04740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_RS04785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F9K57_RS04790	COG2072	flavoprotein involved in K transport
F9K57_RS04795	COG0300	oxidoreductase activity
F9K57_RS04805	COG1309	transcriptional regulator
F9K57_RS04810	COG1741	Belongs to the pirin family
F9K57_RS04825	COG2072	flavoprotein involved in K transport
F9K57_RS04835	COG2252	PERMEase
F9K57_RS04840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F9K57_RS04845	COG3038	cytochrome b561
F9K57_RS04855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F9K57_RS04875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F9K57_RS04885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F9K57_RS04900	COG0667	Aldo Keto reductase
F9K57_RS04910	COG1765	OsmC-like protein
F9K57_RS04960	COG2885	chlorophyll binding
F9K57_RS04970	COG0625	glutathione transferase activity
F9K57_RS04975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F9K57_RS04995	COG3634	alkyl hydroperoxide reductase activity
F9K57_RS05005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F9K57_RS05015	COG0450	alkyl hydroperoxide reductase
F9K57_RS05020	COG1643	Atp-dependent helicase
F9K57_RS05035	COG2814	Major facilitator Superfamily
F9K57_RS05040	COG3135	benzoate transporter
F9K57_RS05045	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS05050	COG0543	2 iron, 2 sulfur cluster binding
F9K57_RS05050	COG0633	Ferredoxin
F9K57_RS05055	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9K57_RS05060	COG4638	Rieske (2fe-2S)
F9K57_RS05065	COG0583	DNA-binding transcription factor activity
F9K57_RS05150	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS05155	COG1278	Cold shock
F9K57_RS05190	COG2814	Major facilitator Superfamily
F9K57_RS05195	COG1733	regulation of RNA biosynthetic process
F9K57_RS05275	COG5410	chromosome segregation
F9K57_RS05395	COG0739	heme binding
F9K57_RS05470	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F9K57_RS05470	COG0517	IMP dehydrogenase activity
F9K57_RS05475	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F9K57_RS05485	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F9K57_RS05490	COG1137	ATPase activity
F9K57_RS05495	COG1538	Outer membrane efflux protein
F9K57_RS05535	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F9K57_RS05550	COG1522	sequence-specific DNA binding
F9K57_RS05555	COG5006	permease, DMT superfamily
F9K57_RS05605	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_RS05630	COG3501	Rhs element vgr protein
F9K57_RS05675	COG0583	DNA-binding transcription factor activity
F9K57_RS05680	COG1914	H( )-stimulated, divalent metal cation uptake system
F9K57_RS05700	COG4770	biotin carboxylase activity
F9K57_RS05710	COG2831	hemolysin activation secretion protein
F9K57_RS05715	COG3210	domain, Protein
F9K57_RS05735	COG1309	transcriptional regulator
F9K57_RS05745	COG1063	alcohol dehydrogenase
F9K57_RS05760	COG0439	Biotin carboxylase
F9K57_RS05765	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS05770	COG1733	regulation of RNA biosynthetic process
F9K57_RS05785	COG0864	Transcriptional regulator
F9K57_RS05795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9K57_RS05800	COG1116	anion transmembrane transporter activity
F9K57_RS05865	COG2885	chlorophyll binding
F9K57_RS05865	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9K57_RS05905	COG0583	DNA-binding transcription factor activity
F9K57_RS05915	COG0590	tRNA wobble adenosine to inosine editing
F9K57_RS05920	COG2807	transmembrane transport
F9K57_RS05935	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F9K57_RS05945	COG0789	Transcriptional regulator
F9K57_RS05955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_RS06000	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS06005	COG0531	amino acid
F9K57_RS06010	COG1760	l-serine dehydratase
F9K57_RS06015	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS06015	COG2030	dehydratase
F9K57_RS06020	COG3396	Phenylacetate-CoA oxygenase
F9K57_RS06025	COG3460	Phenylacetate-CoA oxygenase
F9K57_RS06030	COG3396	Phenylacetate-CoA oxygenase
F9K57_RS06035	COG2151	metal-sulfur cluster biosynthetic enzyme
F9K57_RS06040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_RS06045	COG1024	Enoyl-CoA hydratase
F9K57_RS06050	COG1024	Enoyl-CoA hydratase
F9K57_RS06055	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_RS06060	COG0183	Belongs to the thiolase family
F9K57_RS06065	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F9K57_RS06070	COG3327	negative regulation of DNA-templated transcription, initiation
F9K57_RS06080	COG2050	protein possibly involved in aromatic compounds catabolism
F9K57_RS06090	COG0406	alpha-ribazole phosphatase activity
F9K57_RS06135	COG1278	Cold shock
F9K57_RS06145	COG2207	Transcriptional regulator
F9K57_RS06165	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F9K57_RS06170	COG2271	Major facilitator Superfamily
F9K57_RS06175	COG0753	catalase activity
F9K57_RS06180	COG3038	cytochrome b561
F9K57_RS06200	COG2267	carboxylic ester hydrolase activity
F9K57_RS06205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS06210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_RS06215	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS06225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F9K57_RS06235	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS06240	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9K57_RS06245	COG0583	DNA-binding transcription factor activity
F9K57_RS06255	COG1414	Transcriptional regulator
F9K57_RS06260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_RS06270	COG1840	ABC-type Fe3 transport system, periplasmic component
F9K57_RS06275	COG3842	ATPase activity
F9K57_RS06290	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F9K57_RS06295	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F9K57_RS06300	COG2814	Major facilitator Superfamily
F9K57_RS06305	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS06320	COG1024	Enoyl-CoA hydratase
F9K57_RS06330	COG2814	Major facilitator Superfamily
F9K57_RS06340	COG0183	Belongs to the thiolase family
F9K57_RS06345	COG1250	3-hydroxyacyl-CoA dehydrogenase
F9K57_RS06350	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS06355	COG1024	Enoyl-CoA hydratase
F9K57_RS06360	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS06365	COG2814	Major facilitator Superfamily
F9K57_RS06370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_RS06375	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9K57_RS06385	COG2814	Major facilitator Superfamily
F9K57_RS06395	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS06410	COG0583	DNA-binding transcription factor activity
F9K57_RS06425	COG1024	Enoyl-CoA hydratase
F9K57_RS06430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9K57_RS06435	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS06440	COG1309	transcriptional regulator
F9K57_RS06445	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_RS06510	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS06530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F9K57_RS06570	COG0765	amino acid transport
F9K57_RS06575	COG0765	amino acid transport
F9K57_RS06580	COG1126	abc transporter atp-binding protein
F9K57_RS06590	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F9K57_RS06605	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS06610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F9K57_RS06615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9K57_RS06620	COG1045	serine acetyltransferase
F9K57_RS06635	COG0583	DNA-binding transcription factor activity
F9K57_RS06640	COG0625	glutathione transferase activity
F9K57_RS06645	COG0625	glutathione transferase activity
F9K57_RS06650	COG0583	DNA-binding transcription factor activity
F9K57_RS06660	COG1346	cytolysis
F9K57_RS06680	COG2814	Major facilitator Superfamily
F9K57_RS06690	COG0583	DNA-binding transcription factor activity
F9K57_RS06700	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
F9K57_RS06705	COG3052	prosthetic group binding
F9K57_RS06725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F9K57_RS06745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_RS06755	COG1294	oxidase, subunit
F9K57_RS06760	COG1271	oxidase subunit
F9K57_RS06780	COG0477	Major facilitator Superfamily
F9K57_RS06790	COG4521	taurine ABC transporter
F9K57_RS06795	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F9K57_RS06800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_RS06805	COG2175	clavaminate synthase activity
F9K57_RS06815	COG1953	Uracil, thiamine, allantoin
F9K57_RS06825	COG0583	DNA-binding transcription factor activity
F9K57_RS06835	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F9K57_RS06850	COG0640	Transcriptional regulator
F9K57_RS06855	COG0798	PFAM Bile acid sodium symporter
F9K57_RS06860	COG0583	DNA-binding transcription factor activity
F9K57_RS06875	COG3634	alkyl hydroperoxide reductase activity
F9K57_RS06910	COG1301	dicarboxylic acid transport
F9K57_RS06915	COG0436	Aminotransferase
F9K57_RS06965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F9K57_RS06990	COG0012	GTP binding
F9K57_RS06995	COG2011	ABC-type metal ion transport system permease component
F9K57_RS07000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9K57_RS07010	COG1464	Belongs to the NlpA lipoprotein family
F9K57_RS07040	COG0765	amino acid transport
F9K57_RS07045	COG0765	amino acid transport
F9K57_RS07050	COG1126	abc transporter atp-binding protein
F9K57_RS07060	COG1522	sequence-specific DNA binding
F9K57_RS07075	COG1309	transcriptional regulator
F9K57_RS07145	COG0583	DNA-binding transcription factor activity
F9K57_RS07155	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F9K57_RS07165	COG0697	spore germination
F9K57_RS07185	COG3121	Chaperone
F9K57_RS07190	COG3539	Fimbrial protein
F9K57_RS07215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F9K57_RS07215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F9K57_RS07260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F9K57_RS07270	COG2353	YceI-like domain
F9K57_RS07280	COG3698	Phosphodiester glycosidase
F9K57_RS07295	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F9K57_RS07300	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9K57_RS07300	COG0506	proline dehydrogenase activity
F9K57_RS07300	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F9K57_RS07310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9K57_RS07315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F9K57_RS07335	COG1132	(ABC) transporter
F9K57_RS07340	COG3122	Protein conserved in bacteria
F9K57_RS07345	COG3619	membrane
F9K57_RS07355	COG0640	Transcriptional regulator
F9K57_RS07365	COG2850	peptidyl-arginine hydroxylation
F9K57_RS07370	COG0424	maF-like protein
F9K57_RS07390	COG0191	fructose-bisphosphate aldolase activity
F9K57_RS07395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9K57_RS07410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F9K57_RS07420	COG1192	Involved in chromosome partitioning
F9K57_RS07425	COG1475	DNA binding
F9K57_RS07430	COG0811	peptide transport
F9K57_RS07440	COG1132	(ABC) transporter
F9K57_RS07445	COG1663	tetraacyldisaccharide 4'-kinase activity
F9K57_RS07465	COG0084	hydrolase, TatD family'
F9K57_RS07480	COG2165	general secretion pathway protein
F9K57_RS07510	COG0590	tRNA wobble adenosine to inosine editing
F9K57_RS07530	COG0776	regulation of translation
F9K57_RS07560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F9K57_RS07565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F9K57_RS07615	COG0339	signal peptide processing
F9K57_RS07625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F9K57_RS07660	COG0702	epimerase
F9K57_RS07665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9K57_RS07685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F9K57_RS07715	COG0316	Belongs to the HesB IscA family
F9K57_RS07720	COG0822	iron-sulfur transferase activity
F9K57_RS07745	COG0776	regulation of translation
F9K57_RS07750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F9K57_RS07755	COG2207	Transcriptional regulator
F9K57_RS07760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9K57_RS07765	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS07770	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS07785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F9K57_RS07805	COG4264	IucA IucC family
F9K57_RS07810	COG4264	IucA IucC family
F9K57_RS07820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F9K57_RS07865	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F9K57_RS07870	COG0406	alpha-ribazole phosphatase activity
F9K57_RS07885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9K57_RS07890	COG0730	response to heat
F9K57_RS07910	COG4773	Receptor
F9K57_RS07915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9K57_RS07930	COG1131	(ABC) transporter
F9K57_RS07935	COG0842	Transport permease protein
F9K57_RS07940	COG0842	Transport permease protein
F9K57_RS07995	COG2226	methyltransferase
F9K57_RS08020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F9K57_RS08055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9K57_RS08065	COG0133	tryptophan synthase activity
F9K57_RS08080	COG3706	GGDEF domain
F9K57_RS08095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9K57_RS08100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F9K57_RS08105	COG0022	dehydrogenase e1 component
F9K57_RS08110	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9K57_RS08115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_RS08125	COG1063	alcohol dehydrogenase
F9K57_RS08130	COG3781	membrane
F9K57_RS08150	COG0730	response to heat
F9K57_RS08165	COG2207	Transcriptional regulator
F9K57_RS08165	COG3708	Transcriptional regulator
F9K57_RS08170	COG1733	regulation of RNA biosynthetic process
F9K57_RS08175	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F9K57_RS08200	COG4521	taurine ABC transporter
F9K57_RS08205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_RS08225	COG0477	Major facilitator Superfamily
F9K57_RS08235	COG1027	Aspartate ammonia-lyase
F9K57_RS08250	COG0583	DNA-binding transcription factor activity
F9K57_RS08255	COG0583	DNA-binding transcription factor activity
F9K57_RS08260	COG0183	Belongs to the thiolase family
F9K57_RS08280	COG0583	DNA-binding transcription factor activity
F9K57_RS08290	COG2610	gluconate transmembrane transporter activity
F9K57_RS08295	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08300	COG2207	Transcriptional regulator
F9K57_RS08310	COG0412	Dienelactone hydrolase
F9K57_RS08315	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08325	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS08340	COG0543	2 iron, 2 sulfur cluster binding
F9K57_RS08340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_RS08345	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F9K57_RS08350	COG4638	Rieske (2fe-2S)
F9K57_RS08360	COG0725	ABC transporter, periplasmic molybdate-binding protein
F9K57_RS08365	COG4149	molybdate abc transporter
F9K57_RS08370	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F9K57_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08380	COG1535	isochorismatase
F9K57_RS08380	COG3433	isochorismatase activity
F9K57_RS08445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9K57_RS08460	COG0753	catalase activity
F9K57_RS08470	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F9K57_RS08500	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F9K57_RS08505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS08510	COG0745	RESPONSE REGULATOR receiver
F9K57_RS08515	COG2205	protein histidine kinase activity
F9K57_RS08525	COG2207	Transcriptional regulator
F9K57_RS08545	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08560	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F9K57_RS08595	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F9K57_RS08645	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F9K57_RS08665	COG1120	ATPase activity
F9K57_RS08680	COG1064	alcohol dehydrogenase
F9K57_RS08685	COG2207	Transcriptional regulator
F9K57_RS08690	COG2084	Dehydrogenase
F9K57_RS08700	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F9K57_RS08705	COG0583	DNA-binding transcription factor activity
F9K57_RS08715	COG0129	dihydroxy-acid dehydratase activity
F9K57_RS08720	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS08735	COG1566	PFAM secretion protein HlyD family protein
F9K57_RS08750	COG0583	DNA-binding transcription factor activity
F9K57_RS08810	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_RS08820	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS08830	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS08845	COG0583	DNA-binding transcription factor activity
F9K57_RS08850	COG1309	transcriptional regulator
F9K57_RS08895	COG1902	pentaerythritol trinitrate reductase activity
F9K57_RS08895	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_RS08910	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS08930	COG2186	Transcriptional regulator
F9K57_RS08940	COG0583	DNA-binding transcription factor activity
F9K57_RS08945	COG4948	Mandelate Racemase Muconate Lactonizing
F9K57_RS08950	COG4829	muconolactone delta-isomerase
F9K57_RS08960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_RS08965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F9K57_RS08970	COG0183	Belongs to the thiolase family
F9K57_RS08975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F9K57_RS08985	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS09005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS09025	COG4638	Rieske (2fe-2S)
F9K57_RS09045	COG0154	amidase activity
F9K57_RS09055	COG2814	Major facilitator Superfamily
F9K57_RS09080	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS09085	COG0583	DNA-binding transcription factor activity
F9K57_RS09090	COG1414	Transcriptional regulator
F9K57_RS09105	COG2391	methyltransferase activity
F9K57_RS09115	COG4993	Dehydrogenase
F9K57_RS09120	COG3659	wide pore channel activity
F9K57_RS09125	COG3420	alginic acid biosynthetic process
F9K57_RS09130	COG0710	3-dehydroquinate dehydratase activity
F9K57_RS09135	COG3485	protocatechuate 3,4-dioxygenase
F9K57_RS09140	COG3485	protocatechuate 3,4-dioxygenase
F9K57_RS09145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F9K57_RS09150	COG2271	Major facilitator Superfamily
F9K57_RS09155	COG0596	Alpha beta hydrolase
F9K57_RS09160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F9K57_RS09165	COG0183	Belongs to the thiolase family
F9K57_RS09175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F9K57_RS09185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F9K57_RS09190	COG2323	membrane
F9K57_RS09235	COG0446	pyridine nucleotide-disulphide oxidoreductase
F9K57_RS09235	COG1902	pentaerythritol trinitrate reductase activity
F9K57_RS09250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F9K57_RS09260	COG0542	response to heat
F9K57_RS09265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F9K57_RS09295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9K57_RS09300	COG0569	domain protein
F9K57_RS09305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F9K57_RS09320	COG4774	siderophore transport
F9K57_RS09325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F9K57_RS09335	COG1585	Membrane protein implicated in regulation of membrane protease activity
F9K57_RS09350	COG1294	oxidase, subunit
F9K57_RS09355	COG4890	Cyd operon protein YbgT
F9K57_RS09365	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F9K57_RS09375	COG0552	protein localization to endoplasmic reticulum
F9K57_RS09400	COG0516	GMP reductase activity
F9K57_RS09400	COG0517	IMP dehydrogenase activity
F9K57_RS09405	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9K57_RS09410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F9K57_RS09420	COG0583	DNA-binding transcription factor activity
F9K57_RS09425	COG0024	Methionine aminopeptidase
F9K57_RS09455	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F9K57_RS09455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F9K57_RS09465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9K57_RS09465	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F9K57_RS09465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F9K57_RS09485	COG3300	MHYT domain
F9K57_RS09485	COG5001	Diguanylate cyclase
F9K57_RS09505	COG0659	secondary active sulfate transmembrane transporter activity
F9K57_RS09520	COG1113	amino acid transport
F9K57_RS09530	COG1522	sequence-specific DNA binding
F9K57_RS09555	COG1011	Hydrolase
F9K57_RS09560	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F9K57_RS09570	COG2137	regulation of response to DNA damage stimulus
F9K57_RS09585	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F9K57_RS09605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F9K57_RS09620	COG0575	Belongs to the CDS family
F9K57_RS09625	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F9K57_RS09645	COG3852	Histidine kinase
F9K57_RS09650	COG2204	response regulator
F9K57_RS09710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F9K57_RS09735	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_RS09745	COG0303	'Molybdopterin
F9K57_RS09750	COG0315	cyclic pyranopterin monophosphate synthase activity
F9K57_RS09750	COG0521	Mo-molybdopterin cofactor biosynthetic process
F9K57_RS09765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F9K57_RS09770	COG0243	molybdopterin cofactor binding
F9K57_RS09780	COG0243	molybdopterin cofactor binding
F9K57_RS09785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_RS09790	COG2146	nitrite reductase [NAD(P)H] activity
F9K57_RS09790	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_RS09800	COG0745	RESPONSE REGULATOR receiver
F9K57_RS09805	COG1116	anion transmembrane transporter activity
F9K57_RS09805	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_RS09825	COG0511	ligase activity, forming carbon-carbon bonds
F9K57_RS09860	COG0069	glutamate synthase activity
F9K57_RS09900	COG1454	alcohol dehydrogenase
F9K57_RS09905	COG0824	Thioesterase
F9K57_RS09915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F9K57_RS09945	COG0183	Belongs to the thiolase family
F9K57_RS09955	COG0583	DNA-binding transcription factor activity
F9K57_RS09970	COG1522	sequence-specific DNA binding
F9K57_RS09975	COG3135	benzoate transporter
F9K57_RS09985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F9K57_RS10000	COG0589	response to stress
F9K57_RS10005	COG0488	(ABC) transporter
F9K57_RS10025	COG4773	Receptor
F9K57_RS10055	COG0668	transmembrane transport
F9K57_RS10065	COG1309	transcriptional regulator
F9K57_RS10080	COG1605	Chorismate mutase
F9K57_RS10120	COG0308	aminopeptidase N
F9K57_RS10145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F9K57_RS10150	COG1454	alcohol dehydrogenase
F9K57_RS10170	COG0531	amino acid
F9K57_RS10175	COG4303	Ethanolamine ammonia lyase large subunit
F9K57_RS10180	COG4302	ethanolamine ammonia-lyase activity
F9K57_RS10185	COG0519	Catalyzes the synthesis of GMP from XMP
F9K57_RS10185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9K57_RS10215	COG0697	spore germination
F9K57_RS10220	COG1923	regulation of RNA biosynthetic process
F9K57_RS10230	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F9K57_RS10235	COG0802	atpase or kinase
F9K57_RS10270	COG0583	DNA-binding transcription factor activity
F9K57_RS10285	COG2814	Major facilitator Superfamily
F9K57_RS10290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F9K57_RS10315	COG0729	surface antigen
F9K57_RS10335	COG0174	glutamine synthetase
F9K57_RS10340	COG0745	RESPONSE REGULATOR receiver
F9K57_RS10345	COG2205	protein histidine kinase activity
F9K57_RS10350	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F9K57_RS10355	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F9K57_RS10360	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F9K57_RS10385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS10390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_RS10395	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS10410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_RS10415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_RS10435	COG0583	DNA-binding transcription factor activity
F9K57_RS10450	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_RS10460	COG3658	cytochrome
F9K57_RS10465	COG1215	transferase activity, transferring glycosyl groups
F9K57_RS10470	COG0726	polysaccharide deacetylase
F9K57_RS10470	COG1649	PFAM Uncharacterised BCR, COG1649
F9K57_RS10495	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F9K57_RS10500	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F9K57_RS10510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F9K57_RS10535	COG0305	Participates in initiation and elongation during chromosome replication
F9K57_RS10540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F9K57_RS10550	COG1305	Transglutaminase-like
F9K57_RS10560	COG2308	Evidence 4 Homologs of previously reported genes of
F9K57_RS10590	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F9K57_RS10595	COG0138	bifunctional purine biosynthesis protein purh
F9K57_RS10600	COG0151	Belongs to the GarS family
F9K57_RS10605	COG1464	Belongs to the NlpA lipoprotein family
F9K57_RS10610	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F9K57_RS10615	COG2011	ABC-type metal ion transport system permease component
F9K57_RS10620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_RS10630	COG1301	dicarboxylic acid transport
F9K57_RS10660	COG1794	racemase activity, acting on amino acids and derivatives
F9K57_RS10685	COG0642	Histidine kinase
F9K57_RS10690	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9K57_RS10700	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F9K57_RS10740	COG2351	hydroxyisourate hydrolase activity
F9K57_RS10750	COG3008	intermembrane lipid transfer
F9K57_RS10750	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F9K57_RS10755	COG2995	paraquat-inducible protein a
F9K57_RS10835	COG2186	Transcriptional regulator
F9K57_RS10850	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS10860	COG0583	DNA-binding transcription factor activity
F9K57_RS10875	COG3243	poly(R)-hydroxyalkanoic acid synthase
F9K57_RS10900	COG3111	PFAM Bacterial OB fold (BOF) protein
F9K57_RS10970	COG2815	serine threonine protein kinase
F9K57_RS10970	COG0515	serine threonine protein kinase
F9K57_RS10995	COG0828	Belongs to the bacterial ribosomal protein bS21 family
F9K57_RS11000	COG1610	YqeY-like protein
F9K57_RS11005	COG4783	chaperone-mediated protein folding
F9K57_RS11030	COG1286	toxin biosynthetic process
F9K57_RS11060	COG0778	Nitroreductase
F9K57_RS11070	COG0513	Belongs to the DEAD box helicase family
F9K57_RS11090	COG2363	Small membrane protein
F9K57_RS11120	COG1234	tRNA 3'-trailer cleavage
F9K57_RS11125	COG2195	Cleaves the N-terminal amino acid of tripeptides
F9K57_RS11135	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F9K57_RS11145	COG2819	hydrolase of the alpha beta superfamily
F9K57_RS11150	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS11155	COG1301	dicarboxylic acid transport
F9K57_RS11165	COG3139	Protein of unknown function (DUF1315)
F9K57_RS11170	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F9K57_RS11175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F9K57_RS11185	COG0494	nUDIX hydrolase
F9K57_RS11195	COG0642	Histidine kinase
F9K57_RS11200	COG0745	RESPONSE REGULATOR receiver
F9K57_RS11220	COG1720	tRNA m6t6A37 methyltransferase activity
F9K57_RS11235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_RS11245	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F9K57_RS11255	COG4598	ABC transporter
F9K57_RS11260	COG4160	amino acid transport
F9K57_RS11265	COG4215	(ABC) transporter
F9K57_RS11280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS11290	COG1538	Outer membrane efflux protein
F9K57_RS11325	COG1131	(ABC) transporter
F9K57_RS11330	COG0842	Transport permease protein
F9K57_RS11345	COG0772	Belongs to the SEDS family
F9K57_RS11350	COG2951	lytic endotransglycosylase activity
F9K57_RS11375	COG2207	Transcriptional regulator
F9K57_RS11390	COG0052	Belongs to the universal ribosomal protein uS2 family
F9K57_RS11395	COG0024	Methionine aminopeptidase
F9K57_RS11405	COG2223	nitrite transmembrane transporter activity
F9K57_RS11415	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_RS11420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F9K57_RS11425	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS11440	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F9K57_RS11445	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F9K57_RS11450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9K57_RS11470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9K57_RS11475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9K57_RS11480	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F9K57_RS11515	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F9K57_RS11530	COG3104	oligopeptide transport
F9K57_RS11540	COG0512	Glutamine amidotransferase of anthranilate synthase
F9K57_RS11545	COG0308	aminopeptidase N
F9K57_RS11575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F9K57_RS11605	COG3739	integral membrane protein
F9K57_RS11630	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F9K57_RS11635	COG5265	(ABC) transporter
F9K57_RS11640	COG1132	(ABC) transporter
F9K57_RS11655	COG3433	isochorismatase activity
F9K57_RS11655	COG1535	isochorismatase
F9K57_RS11660	COG1021	2,3-dihydroxybenzoate-AMP ligase
F9K57_RS11665	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9K57_RS11675	COG4774	siderophore transport
F9K57_RS11680	COG4607	ABC-type enterochelin transport system periplasmic component
F9K57_RS11685	COG4604	ABC transporter, ATP-binding protein
F9K57_RS11690	COG4605	iron ion homeostasis
F9K57_RS11695	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F9K57_RS11715	COG2964	Protein conserved in bacteria
F9K57_RS11725	COG1741	Belongs to the pirin family
F9K57_RS11760	COG2879	small protein
F9K57_RS11765	COG1966	Carbon starvation protein
F9K57_RS11785	COG4943	cyclic-guanylate-specific phosphodiesterase activity
F9K57_RS11810	COG1067	ATP-dependent peptidase activity
F9K57_RS11815	COG0583	DNA-binding transcription factor activity
F9K57_RS11840	COG1686	Belongs to the peptidase S11 family
F9K57_RS11845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F9K57_RS11880	COG0616	signal peptide processing
F9K57_RS11885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F9K57_RS11895	COG0573	inorganic phosphate transmembrane transporter activity
F9K57_RS11900	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F9K57_RS11905	COG1113	amino acid transport
F9K57_RS11910	COG3961	Belongs to the TPP enzyme family
F9K57_RS11915	COG1522	sequence-specific DNA binding
F9K57_RS11925	COG0076	glutamate decarboxylase activity
F9K57_RS11930	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9K57_RS11945	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS11955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_RS11990	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_RS12015	COG0612	Peptidase, M16
F9K57_RS12030	COG0583	DNA-binding transcription factor activity
F9K57_RS12035	COG0477	Major facilitator Superfamily
F9K57_RS12060	COG1187	pseudouridine synthase activity
F9K57_RS12075	COG1686	Belongs to the peptidase S11 family
F9K57_RS12080	COG1252	NADH dehydrogenase
F9K57_RS12090	COG0415	Belongs to the DNA photolyase family
F9K57_RS12105	COG1215	transferase activity, transferring glycosyl groups
F9K57_RS12135	COG2070	2-Nitropropane dioxygenase
F9K57_RS12190	COG0556	nucleotide-excision repair
F9K57_RS12250	COG4221	oxidoreductase activity
F9K57_RS12260	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F9K57_RS12265	COG1381	Involved in DNA repair and RecF pathway recombination
F9K57_RS12275	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F9K57_RS12290	COG0681	Belongs to the peptidase S26 family
F9K57_RS12305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F9K57_RS12325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F9K57_RS12330	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F9K57_RS12335	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F9K57_RS12345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F9K57_RS12350	COG4208	sulfate ABC transporter
F9K57_RS12355	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F9K57_RS12360	COG0583	DNA-binding transcription factor activity
F9K57_RS12365	COG4625	pathogenesis
F9K57_RS12380	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F9K57_RS12395	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F9K57_RS12405	COG1056	cytidyltransferase-related domain
F9K57_RS12405	COG1051	belongs to the nudix hydrolase family
F9K57_RS12410	COG1024	Enoyl-CoA hydratase
F9K57_RS12415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F9K57_RS12420	COG2814	Major facilitator Superfamily
F9K57_RS12425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F9K57_RS12425	COG0047	phosphoribosylformylglycinamidine synthase activity
F9K57_RS12445	COG1473	amidohydrolase
F9K57_RS12450	COG0824	Thioesterase
F9K57_RS12470	COG0823	Involved in the tonB-independent uptake of proteins
F9K57_RS12490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F9K57_RS12525	COG0628	permease
F9K57_RS12535	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F9K57_RS12540	COG0596	Alpha beta hydrolase
F9K57_RS12545	COG0616	signal peptide processing
F9K57_RS12545	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F9K57_RS12555	COG2333	competence protein COMEC
F9K57_RS12555	COG0658	competence protein
F9K57_RS12560	COG1136	(ABC) transporter
F9K57_RS12565	COG4591	ABC-type transport system involved in lipoprotein release permease component
F9K57_RS12595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS12615	COG0463	Glycosyl transferase, family 2
F9K57_RS12645	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F9K57_RS12650	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS12655	COG2267	carboxylic ester hydrolase activity
F9K57_RS12665	COG0019	diaminopimelate decarboxylase activity
F9K57_RS12675	COG1113	amino acid transport
F9K57_RS12690	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F9K57_RS12700	COG3339	Conserved Protein
F9K57_RS12705	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F9K57_RS12710	COG0243	molybdopterin cofactor binding
F9K57_RS12715	COG1929	Belongs to the glycerate kinase type-1 family
F9K57_RS12730	COG0778	Nitroreductase
F9K57_RS12750	COG3811	Belongs to the UPF0386 family
F9K57_RS12795	COG0741	lytic transglycosylase activity
F9K57_RS12815	COG0584	glycerophosphoryl diester phosphodiesterase
F9K57_RS12820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_RS12845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_RS12870	COG0477	Major facilitator Superfamily
F9K57_RS12880	COG2264	protein methyltransferase activity
F9K57_RS12920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F9K57_RS12925	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F9K57_RS12950	COG0505	Belongs to the CarA family
F9K57_RS12965	COG1309	transcriptional regulator
F9K57_RS12970	COG0251	oxidation-reduction process
F9K57_RS12980	COG0589	response to stress
F9K57_RS12995	COG2843	Capsule synthesis protein
F9K57_RS13015	COG2321	neutral zinc metallopeptidase
F9K57_RS13020	COG2354	Protein conserved in bacteria
F9K57_RS13040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F9K57_RS13065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F9K57_RS13070	COG1053	succinate dehydrogenase
F9K57_RS13075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F9K57_RS13080	COG2009	succinate dehydrogenase
F9K57_RS13125	COG2921	Belongs to the UPF0250 family
F9K57_RS13130	COG0321	lipoyl(octanoyl) transferase activity
F9K57_RS13145	COG0531	amino acid
F9K57_RS13160	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F9K57_RS13165	COG1648	precorrin-2 dehydrogenase activity
F9K57_RS13165	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F9K57_RS13180	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F9K57_RS13210	COG0671	phosphoesterase, PA-phosphatase related
F9K57_RS13215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS13225	COG1538	Outer membrane efflux protein
F9K57_RS13230	COG0393	Putative heavy-metal-binding
F9K57_RS13235	COG0393	Putative heavy-metal-binding
F9K57_RS13245	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS13255	COG0525	valine-tRNA ligase activity
F9K57_RS13280	COG0583	DNA-binding transcription factor activity
F9K57_RS13285	COG0004	ammonium transporteR
F9K57_RS13295	COG0642	Histidine kinase
F9K57_RS13300	COG0745	RESPONSE REGULATOR receiver
F9K57_RS13305	COG2194	sulfuric ester hydrolase activity
F9K57_RS13325	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9K57_RS13340	COG2315	Protein conserved in bacteria
F9K57_RS13345	COG0142	geranyltranstransferase activity
F9K57_RS13350	COG2828	Protein conserved in bacteria
F9K57_RS13355	COG1113	amino acid transport
F9K57_RS13375	COG2207	Transcriptional regulator
F9K57_RS13400	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS13420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F9K57_RS13430	COG1530	ribonuclease E activity
F9K57_RS13435	COG0424	maF-like protein
F9K57_RS13440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F9K57_RS13445	COG1792	Involved in formation and maintenance of cell shape
F9K57_RS13450	COG1077	Cell shape determining protein MreB Mrl
F9K57_RS13455	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9K57_RS13465	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F9K57_RS13495	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F9K57_RS13500	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F9K57_RS13505	COG1752	Esterase of the alpha-beta hydrolase superfamily
F9K57_RS13510	COG1115	amino acid carrier protein
F9K57_RS13535	COG1289	transmembrane transporter activity
F9K57_RS13585	COG1376	ErfK ybiS ycfS ynhG family protein
F9K57_RS13590	COG2832	Protein of unknown function (DUF454)
F9K57_RS13600	COG5510	response to toxic substance
F9K57_RS13620	COG0840	transmembrane signaling receptor activity
F9K57_RS13660	COG3422	double-strand break repair
F9K57_RS13665	COG2824	Alkylphosphonate utilization operon protein PhnA
F9K57_RS13670	COG3189	MarR family transcriptional regulator
F9K57_RS13680	COG0354	folic acid binding
F9K57_RS13685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_RS13695	COG0679	Auxin Efflux Carrier
F9K57_RS13700	COG1902	pentaerythritol trinitrate reductase activity
F9K57_RS13705	COG4772	TonB-dependent receptor
F9K57_RS13710	COG2094	Belongs to the DNA glycosylase MPG family
F9K57_RS13740	COG2233	PERMEase
F9K57_RS13750	COG0833	amino acid
F9K57_RS13755	COG1690	Belongs to the RtcB family
F9K57_RS13760	COG2885	chlorophyll binding
F9K57_RS13760	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F9K57_RS13770	COG0183	Belongs to the thiolase family
F9K57_RS13790	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F9K57_RS13810	COG2207	Transcriptional regulator
F9K57_RS13815	COG0183	Belongs to the thiolase family
F9K57_RS13845	COG1272	protein, Hemolysin III
F9K57_RS13850	COG0477	Major facilitator Superfamily
F9K57_RS13865	COG0450	alkyl hydroperoxide reductase
F9K57_RS13885	COG0285	dihydrofolate synthase activity
F9K57_RS13920	COG0133	tryptophan synthase activity
F9K57_RS13930	COG4206	TonB-dependent receptor
F9K57_RS13935	COG2096	Adenosyltransferase
F9K57_RS13940	COG0584	glycerophosphoryl diester phosphodiesterase
F9K57_RS13955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F9K57_RS13960	COG0745	RESPONSE REGULATOR receiver
F9K57_RS13965	COG2205	protein histidine kinase activity
F9K57_RS13975	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS13980	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS13985	COG3223	Belongs to the PsiE family
F9K57_RS14045	COG0438	transferase activity, transferring glycosyl groups
F9K57_RS14050	COG0463	Glycosyl transferase, family 2
F9K57_RS14055	COG0726	polysaccharide deacetylase
F9K57_RS14075	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F9K57_RS14080	COG2205	protein histidine kinase activity
F9K57_RS14115	COG1862	Preprotein translocase
F9K57_RS14125	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F9K57_RS14130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F9K57_RS14140	COG3781	membrane
F9K57_RS14145	COG0613	PHP domain protein
F9K57_RS14155	COG2350	Protein conserved in bacteria
F9K57_RS14185	COG1607	acyl-coa hydrolase
F9K57_RS14200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F9K57_RS14200	COG3453	Protein conserved in bacteria
F9K57_RS14255	COG1408	metallophosphoesterase
F9K57_RS14260	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F9K57_RS14270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F9K57_RS14290	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F9K57_RS14295	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F9K57_RS14310	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F9K57_RS14320	COG2969	positive regulation of protein catabolic process
F9K57_RS14340	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS14345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F9K57_RS14365	COG1309	transcriptional regulator
F9K57_RS14370	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS14415	COG1183	phosphatidylcholine synthase activity
F9K57_RS14420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F9K57_RS14450	COG0739	heme binding
F9K57_RS14450	COG1196	nuclear chromosome segregation
F9K57_RS14450	COG0741	lytic transglycosylase activity
F9K57_RS14460	COG1702	phosphate starvation-inducible protein PhoH
F9K57_RS14495	COG1295	ribonuclease BN
F9K57_RS14500	COG0697	spore germination
F9K57_RS14505	COG2169	Transcriptional regulator
F9K57_RS14510	COG0179	Fumarylacetoacetate (FAA) hydrolase
F9K57_RS14555	COG0557	exoribonuclease II activity
F9K57_RS14560	COG0339	signal peptide processing
F9K57_RS14565	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F9K57_RS14595	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F9K57_RS14600	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS14625	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F9K57_RS14635	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F9K57_RS14755	COG0626	cystathionine gamma-synthase activity
F9K57_RS14760	COG0433	COG0433 Predicted ATPase
F9K57_RS14770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F9K57_RS14770	COG1017	nitric oxide dioxygenase activity
F9K57_RS14775	COG1959	2 iron, 2 sulfur cluster binding
F9K57_RS14790	COG1301	dicarboxylic acid transport
F9K57_RS14795	COG1946	Acyl-CoA thioesterase
F9K57_RS14815	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F9K57_RS14820	COG1040	competence protein
F9K57_RS14825	COG0494	nUDIX hydrolase
F9K57_RS14835	COG0598	Magnesium transport protein CorA
F9K57_RS14845	COG2854	intermembrane phospholipid transfer
F9K57_RS14855	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F9K57_RS14860	COG1127	ABC transporter
F9K57_RS14865	COG0513	Belongs to the DEAD box helicase family
F9K57_RS14885	COG0408	coproporphyrinogen oxidase activity
F9K57_RS14900	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS14915	COG0517	IMP dehydrogenase activity
F9K57_RS14965	COG0583	DNA-binding transcription factor activity
F9K57_RS15005	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS15015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F9K57_RS15020	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F9K57_RS15025	COG0833	amino acid
F9K57_RS15055	COG1192	Involved in chromosome partitioning
F9K57_RS15060	COG0628	permease
F9K57_RS15070	COG1289	transmembrane transporter activity
F9K57_RS15085	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS15090	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F9K57_RS15100	COG0277	FAD linked oxidase domain protein
F9K57_RS15105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F9K57_RS15130	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F9K57_RS15135	COG5380	lipid catabolic process
F9K57_RS15155	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F9K57_RS15210	COG0194	GDP metabolic process
F9K57_RS15225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F9K57_RS15255	COG4969	Belongs to the N-Me-Phe pilin family
F9K57_RS15265	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F9K57_RS15270	COG1704	LemA family
F9K57_RS15280	COG0493	'glutamate synthase
F9K57_RS15285	COG0070	glutamate synthase
F9K57_RS15285	COG0069	glutamate synthase activity
F9K57_RS15285	COG0067	glutamate synthase
F9K57_RS15335	COG2226	methyltransferase
F9K57_RS15350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F9K57_RS15355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F9K57_RS15400	COG0833	amino acid
F9K57_RS15465	COG0488	(ABC) transporter
F9K57_RS15475	COG4221	oxidoreductase activity
F9K57_RS15480	COG0659	secondary active sulfate transmembrane transporter activity
F9K57_RS15495	COG0745	RESPONSE REGULATOR receiver
F9K57_RS15510	COG0427	acetyl-CoA hydrolase
F9K57_RS15540	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F9K57_RS15580	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F9K57_RS15650	COG2249	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS15655	COG1733	regulation of RNA biosynthetic process
F9K57_RS15690	COG0667	Aldo Keto reductase
F9K57_RS15715	COG0583	DNA-binding transcription factor activity
F9K57_RS15720	COG2814	Major facilitator Superfamily
F9K57_RS15750	COG1335	isochorismatase
F9K57_RS15760	COG1012	belongs to the aldehyde dehydrogenase family
F9K57_RS15765	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F9K57_RS15775	COG1113	amino acid transport
F9K57_RS15800	COG2814	Major facilitator Superfamily
F9K57_RS15810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F9K57_RS15810	COG0352	thiamine-phosphate diphosphorylase activity
F9K57_RS15810	COG0351	phosphomethylpyrimidine kinase
F9K57_RS15830	COG1309	transcriptional regulator
F9K57_RS15850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F9K57_RS15860	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F9K57_RS15865	COG3162	membrane
F9K57_RS15870	COG2198	Histidine kinase
F9K57_RS15870	COG2205	protein histidine kinase activity
F9K57_RS15870	COG0784	Response regulator, receiver
F9K57_RS15895	COG1522	sequence-specific DNA binding
F9K57_RS15900	COG1335	isochorismatase
F9K57_RS15905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_RS15915	COG0668	transmembrane transport
F9K57_RS15920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F9K57_RS15925	COG1519	Transferase
F9K57_RS15930	COG1902	pentaerythritol trinitrate reductase activity
F9K57_RS15950	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F9K57_RS15975	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F9K57_RS15975	COG0426	domain, Protein
F9K57_RS15985	COG2119	membrane
F9K57_RS15995	COG0508	dehydrogenase complex catalyzes the overall conversion of
F9K57_RS16005	COG4942	peptidase
F9K57_RS16030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F9K57_RS16050	COG0189	ligase activity
F9K57_RS16070	COG0708	Exodeoxyribonuclease III
F9K57_RS16075	COG1393	Belongs to the ArsC family
F9K57_RS16090	COG3706	GGDEF domain
F9K57_RS16125	COG2351	hydroxyisourate hydrolase activity
F9K57_RS16130	COG2233	PERMEase
F9K57_RS16140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F9K57_RS16150	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F9K57_RS16160	COG3150	esterase
F9K57_RS16185	COG2918	glutathione biosynthetic process
F9K57_RS16200	COG2733	membrane
F9K57_RS16205	COG0436	Aminotransferase
F9K57_RS16210	COG0534	Mate efflux family protein
F9K57_RS16295	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F9K57_RS16300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F9K57_RS16310	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F9K57_RS16335	COG0010	Belongs to the arginase family
F9K57_RS16365	COG2188	Transcriptional regulator
F9K57_RS16375	COG0523	cobalamin synthesis protein
F9K57_RS16385	COG1113	amino acid transport
F9K57_RS16395	COG0625	glutathione transferase activity
F9K57_RS16415	COG1683	Conserved Protein
F9K57_RS16420	COG0534	Mate efflux family protein
F9K57_RS16425	COG0385	Bile acid
F9K57_RS16430	COG1335	isochorismatase
F9K57_RS16435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_RS16455	COG2116	formate transmembrane transporter activity
F9K57_RS16460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F9K57_RS16475	COG3188	usher protein
F9K57_RS16480	COG3121	Chaperone
F9K57_RS16490	COG2983	Belongs to the UPF0260 family
F9K57_RS16510	COG1194	a g-specific adenine glycosylase
F9K57_RS16525	COG2818	Glycosylase
F9K57_RS16530	COG1064	alcohol dehydrogenase
F9K57_RS16535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_RS16550	COG0583	DNA-binding transcription factor activity
F9K57_RS16555	COG0656	L-ascorbic acid biosynthetic process
F9K57_RS16560	COG2814	Major facilitator Superfamily
F9K57_RS16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F9K57_RS16610	COG2233	PERMEase
F9K57_RS16615	COG0583	DNA-binding transcription factor activity
F9K57_RS16640	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F9K57_RS16650	COG0733	neurotransmitter:sodium symporter activity
F9K57_RS16690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F9K57_RS16695	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F9K57_RS16700	COG0596	Alpha beta hydrolase
F9K57_RS16725	COG0488	(ABC) transporter
F9K57_RS16730	COG0586	Pfam SNARE associated Golgi protein
F9K57_RS16740	COG0187	DNA topoisomerase II activity
F9K57_RS16750	COG0592	DNA-directed DNA polymerase activity
F9K57_RS16760	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F9K57_RS16775	COG0706	membrane insertase activity
F9K57_RS16795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_RS16810	COG0402	S-adenosylhomocysteine deaminase activity
F9K57_RS16820	COG0754	glutathionylspermidine amidase activity
F9K57_RS16830	COG0861	Integral membrane protein TerC family
F9K57_RS16835	COG0671	phosphoesterase, PA-phosphatase related
F9K57_RS16845	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F9K57_RS16860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F9K57_RS16865	COG2951	lytic endotransglycosylase activity
F9K57_RS16920	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F9K57_RS16960	COG1047	Peptidyl-prolyl cis-trans
F9K57_RS16975	COG0196	riboflavin kinase activity
F9K57_RS16985	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F9K57_RS16995	COG1116	anion transmembrane transporter activity
F9K57_RS17000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F9K57_RS17005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F9K57_RS17015	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F9K57_RS17035	COG1028	Short-chain dehydrogenase reductase Sdr
F9K57_RS17040	COG0546	phosphoglycolate phosphatase activity
F9K57_RS17095	COG3023	N-Acetylmuramoyl-L-alanine amidase
F9K57_RS17100	COG0728	peptidoglycan biosynthetic process
F9K57_RS17130	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F9K57_RS17175	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F9K57_RS17180	COG0297	glycogen (starch) synthase activity
F9K57_RS17185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F9K57_RS17195	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F9K57_RS17205	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F9K57_RS17220	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F9K57_RS17230	COG2186	Transcriptional regulator
F9K57_RS17240	COG0277	FAD linked oxidase domain protein
F9K57_RS17245	COG1448	Aminotransferase
F9K57_RS17255	COG1802	Transcriptional regulator
F9K57_RS17270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F9K57_RS17295	COG1051	belongs to the nudix hydrolase family
F9K57_RS17320	COG0564	pseudouridine synthase activity
F9K57_RS17345	COG1522	sequence-specific DNA binding
F9K57_RS17360	COG0251	oxidation-reduction process
F9K57_RS17365	COG1113	amino acid transport
F9K57_RS17370	COG1113	amino acid transport
F9K57_RS17390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F9K57_RS17395	COG1960	acyl-CoA dehydrogenase activity
F9K57_RS17400	COG1024	Enoyl-CoA hydratase
F9K57_RS17405	COG1024	Enoyl-CoA hydratase
F9K57_RS17410	COG0477	Major facilitator Superfamily
F9K57_RS17415	COG2197	response regulator
F9K57_RS17440	COG0271	Belongs to the BolA IbaG family
F9K57_RS17450	COG1192	Involved in chromosome partitioning
F9K57_RS17465	COG0586	Pfam SNARE associated Golgi protein
F9K57_RS17470	COG2259	Doxx family
F9K57_RS17475	COG4399	Belongs to the UPF0754 family
F9K57_RS17480	COG0519	Catalyzes the synthesis of GMP from XMP
F9K57_RS17480	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F9K57_RS17525	COG0281	malic enzyme
F9K57_RS17530	COG2837	iron assimilation
F9K57_RS17535	COG1280	lysine exporter protein (LysE YggA)
F9K57_RS17540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F9K57_RS17545	COG1121	(ABC) transporter
F9K57_RS17610	COG0386	Belongs to the glutathione peroxidase family
F9K57_RS17625	COG1309	transcriptional regulator
F9K57_RS17630	COG0697	spore germination
F9K57_RS17640	COG0758	DNA mediated transformation
F9K57_RS17675	COG1309	transcriptional regulator
F9K57_RS17710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F9K57_RS17720	COG0655	NAD(P)H dehydrogenase (quinone) activity
F9K57_RS17755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F9K57_RS17765	COG0477	Major facilitator Superfamily
F9K57_RS17775	COG1253	flavin adenine dinucleotide binding
F9K57_RS17780	COG3012	SEC-C Motif Domain Protein
F9K57_RS17785	COG2860	membrane
F9K57_RS17790	COG0477	Major facilitator Superfamily
F9K57_RS17800	COG0318	PFAM AMP-dependent synthetase and ligase
F9K57_RS17815	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F9K57_RS17830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F9K57_RS17840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F9K57_RS17845	COG0606	chelatase, subunit chli
F9K57_RS17855	COG0347	Belongs to the P(II) protein family
F9K57_RS17860	COG0004	ammonium transporteR
F9K57_RS17870	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9K57_RS17870	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F9K57_RS17910	COG0795	lipopolysaccharide-transporting ATPase activity
F9K57_RS17915	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F9K57_RS17920	COG0793	Belongs to the peptidase S41A family
F9K57_RS17935	COG2197	response regulator
F9K57_RS17945	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F9K57_RS17955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F9K57_RS17985	COG0772	Belongs to the SEDS family
F9K57_RS17990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F9K57_RS17995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F9K57_RS18000	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F9K57_RS18005	COG0494	nUDIX hydrolase